5(6) rox

5(6)-ROX, a nucleic acid fluorescent label, serves as a reference dye in real-time polymerase chain reaction (PCR) applications.

ROX dyes have a strong red fluorescence.Their excitation and emission wavelengths are longer than those of traditional rhodamine dyes.They are used as labels for peptides, proteins, and other biological ligands.5-ROX, 6-ROx, and their mixture of 5(6) -RoX

5(6)-ROX, SE is an amine-reactive fluorescent probe that is widely used for oligonucleotide labeling and automated DNA sequencing applications.

5-ROX, SE ([5-Carboxy-X-rhodamine, succinimidyl ester] *Single isomer*) 是一种标记试剂，用于制备电荷修饰的染料标记的双脱氧核苷酸三磷酸 (ddNTP) 以“直接加载”DNA 测序。

5(6)-TAMRA SE (5(6)-Carboxytetramethylrhodamine N-succinimidyl ester) 是荧光染料，能够结合寡聚核苷酸，并用于DNA 测序。

5(6)-FITC（Fluorescein isothiocyanate）是一种多功能的氨基反应性荧光素染料衍生物。它作为一种有效的标签用于抗体和其他探针，在荧光显微镜检查、流式细胞术以及基于免疫荧光的检测如ELISA和Western blotting中具有实用价值。

6-ROX (6-Carboxy-X-rhodamine) 是寡核苷酸的荧光标记物，其激发波长和发射波长均为568nm。它是耦合至5-FAM 的受体，在FRET 成像中作为供体。

5(6)-Aminofluorescein (5(6)-AFM) 是一种合成 5(6)-FITC 的前体。其中5(6)-FITC 是胺活性衍生物的荧光染料。

5(6)-FAM SE (5(6)-Carboxyfluorescein N-hydroxysuccinimide ester) 是绿色荧光染料，普遍用于标记蛋白质。

5(6)-Carboxyfluorescein (5-(and-6)-Carboxyfluorescein mixed isomers) 是一种胺反应性 pH 敏感的绿色荧光标记物，能够标记蛋白质、多肽和氨基酸，可用于体内实验检测肿瘤位置。

5-ROX (5-Carboxy-X-rhodamine) 是罗丹明染料的一种，λexit 为 580 nm (ε=3.6×104M-1cm-1)，λemit 为 604 nm (ϕ=0.94)。

6-ROX (6-Carboxy-X-rhodamine) hydrochloride 用作寡核苷酸的荧光标记物，并在FRET成像中充当与5-FAM耦合的受体的供体。它的激发波长和发射波长均为568 nm。

5(6)-TAMRA contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid. This bright, orange-fluorescent dye produces conjugates with absorption/emission maxima of ~555/580 nm.

HKSOX-1m (5 6-mixture) serves as a mitochondria-targeting O2 fluorescent probe with an excitation emission wavelength of 509 534nm (green), showcasing exceptional selectivity and sensitivity for O2 across a wide pH spectrum and in the presence of strong oxidants and prevalent reductants within cells.

HKSOX-1r (5 6-mixture) 为用于成像及检测活细胞和体内内源性超氧化物的荧光探针，对超氧阴离子自由基展现出极佳的选择性与敏感性。储存方式：避光。

Flutax-2 (5/6-mixture)为紫杉醇的一种活性荧光衍生物，能与α,β微管蛋白二聚体发生结合。其激发/发射波长分别为496/524 nm。紫杉醇作为红豆杉属植物产生的二萜类次生代谢物，在多种癌症研究中有应用。Flutax-2的储存应避光处理。

5(6)-Carboxyeosin-diacetate是一种多功能染料，广泛用于生物实验中，帮助研究人员观察和分析细胞结构、追踪生物分子、评估细胞功能、区分细胞类型、检测生物分子、研究组织病理及监测微生物。其应用范围从基础科学研究到临床诊断，并在传统领域如纺织品染色和新兴领域如功能性纺织品处理、食品色素及染料敏化太阳能电池等均有广泛应用。

5(6)-Carboxynaphthofluorescein diacetate serves as a fluorescent substrate in esterase assays, where it is cleaved by intracellular esterases, resulting in red fluorescence for enzyme activity measurement (Ex = 590 nm; Em = 645 nm) [1].

5(6)-SFX, SE (Compound SFX-SE) 是一种荧光染料，用于标记伯胺和新生蛋白。

5(6)-TRITC [Tetramethylrhodamine-5-(and-6) -Isothiocyanate] *Mixed isomers* is used to label antibodies with strong fluorescent dyes

5-(6)-Carboxy RhodFluor is a cell-impermeant pH indicator.

The cell-permeant pH indicator, carboxy SNARF-1, acetoxymethyl ester, acetate (CAS #126208-13-7) has a pKa of ~7.5 after de-esterification, thus is useful for measuring pH changes between pH 7 and pH 8. Carboxy-SNARF-1 exhibits a significant pH-dependent

5(6)-Carboxy-eosin是一种多功能染料，在生物实验中的应用广泛，可帮助研究人员观察和分析细胞结构、追踪生物分子、评估细胞功能、区分细胞类型、检测生物分子、研究组织病理及监测微生物，涵盖从基础科学研究到临床诊断；此外，染料还广泛用于传统领域如纺织品染色，新兴领域如功能性纺织品处理、食品色素和染料敏化太阳能电池等。

5(6)-Carboxy-2’,7’-dichlorofluorescein diacetate is an oxidant-sensitive and cell-permeable fluorescent probe.1Base hydrolysis of the ester bonds by intracellular esterases releases the acetate groups and the resulting compound, 5(6)-carboxy-2’,7’,-dichlorofluorescein, is oxidized by reactive oxygen species (ROS) and nitric oxide (NO) and displays excitation emission maxima of 504 and 530 nm, respectively, which can be quantified as a measure of oxidant production. 1.Hempel, S.L., Buettner, G.R., O’Malley, Y.Q., et al.Dihydrofluorescein diacetate is superior for detecting intracellular oxidants: Comparison with 2’,7’-dichlorodihydrofluorescein diacetate, 5(and 6)-carboxy-2’,7’-dichlorodihydrofluorescein diacetate, and dihydrorhodamine 123Free Radic. Biol. Med.27(1-2)146-159(1999)

5(6)-CR110 [5-(and 6)-Carboxyrhodamine 110] *Mixed isomers* is a Fluorescein for peptide and oligonucleotide labeling. Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength. They are photostable alternative reagents superior to FITC and FAM.

HKSOX-1m (5/6-mixture) hydrobromide 是靶向线粒体的 O2•−荧光探针(Ex/Em=509/534 nm; 绿色)，具有极好的选择性，且在较大范围的 pH 值区间，细胞中即使有大量强氧化剂和还原剂的时候依然有效。

Sodium 2,2',2'',2'''-((((1,1-dioxido-3H-benzo[c][1,2]oxathiole-3,3-diyl)bis(6-hydroxy-5-isopropyl-2-methyl-3,1-phenylene))bis(methylene))bis(azanetriyl))tetraacetate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65315，CAS号为 1945-77-3。

5(6)-CFDA (5-(6)-Carboxyfluorescein diacetate) 是具有细胞渗透性的胺反应型绿色荧光探针(λex: 492 nm; λem: 517 nm)，可用于细胞染色分析。

Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) TFA 为基于荧光共振能量转移的多肽底物，通过裂解引起的荧光强度变化来确定其活性。

5(6)-Carboxyfluorescein diisobutyrate, a protected form of 5(6)-carboxyfluorescein, serves as a fluorescence pH indicator [1].

ROX NHS酯，6-异构体，是一种具有高荧光和光稳定性的罗丹明染料，适用于各种应用。ROX标记的寡核苷酸探针常用于qPCR，[qPCR仪器具有ROX通道]。这种活性染料用于标记肽、蛋白质和氨基寡核苷酸中的氨基，且为纯单一异构体。

5(6)-Carboxy-2',7'-dichlorofluorescein diacetate N-succinimidyl ester (cDCFDASE) 是一种用于检测细胞内 pH (pHin) 的荧光探针，特别适用于评估活细胞在中等 pH (pHex) 环境中的 pH 值。

HKSOX-1 是一种荧光探针，用于成像和检测活细胞以及体内的内源性超氧化物。 HKSOX-1 对超氧阴离子自由基具有极好的选择性和敏感性。储存方式：避光。

5(6)-CR110, SE [5-(and 6)-Carboxyrhodamine 110, succinimidyl ester] *Mixed isomers* is a Fluorescein for peptide and oligonucleotide labeling. Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength. They are photostable alternative reagents superior to FITC and FAM.

5(6)-TAMRA (5(6)-Carboxytetramethylrhodamine) 是一种荧光染料分子，广泛地被用作多肽和蛋白质的标记。

NHS-5(6)Carboxyrhodamine is a fluorescent dye employed for precise labeling of proteins through fluorescence. This compound enables the achievement of accurate ratios of dye to protein, even when used under native conditions.

(5)6-Carboxytetramethylrhodamine 是一种广泛用于多肽和蛋白质标记的荧光染料分子 (Ex=~555 nm; Em=580 nm)。

5(6)-Carboxy-2',7'-dichlorofluorescein，作为一种荧光素，被广泛应用于MRP2囊泡转运实验中，由于其出色的检测和转运特性，成为实验中的理想底物。

5(6)-Carboxynaphthofluorescein 是一种 pH 依赖的荧光团，在碱性 pH 范围内显示良好灵敏度，适用于光纤 pH 传感器的构建，并可用作荧光 pH 指示剂。

5-ROX-alkyne 是一种罗丹明染料，可用于标记 DNA 片段，使毛细管电泳的基因分型实验和凝胶迁移实验的结果可视化。

The isomeric 6-ROX, SE is an amine-reactive form of carboxy-X-rhodamine and is widely used for oligonucleotide labeling and automated DNA sequencing applications.