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TMPJ-00263
|
VSIG8 Protein, Human, Recombinant (His)
C1orf204,V-set and immunoglobulin domain-containing protein ...
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Human
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HEK293 Cells
|
|
V-set and immunoglobulin domain-containing protein 8(VSIG8) is a single-pass type I membrane protein.The human VSIG8 cDNA encodes 414 amino acids (aa) including a 21 aa signal sequence, a 242 aa extracellular domain (ECD) containing 2 Ig-like V-type (immunoglobulin-like) domains, a 21 aa transmembrane domain and a 130 aa cytoplasmic domain.The funtion of VSIG8 is not clear. |
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TMPJ-01180
|
VSIG8 Protein, Mouse, Recombinant (His)
Vsig8,V-set and immunoglobulin domain-containing protein 8
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Mouse
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HEK293 Cells
|
|
V-set and immunoglobulin domain-containing protein 8(VSIG8) is a single-pass type I membrane protein.The mouse VSIG8 cDNA encodes 417 amino acids (aa) including a 21 aa signal sequence, a 241 aa extracellular domain (ECD) containing 2 Ig-like V-type (immunoglobulin-like) domains, a 21 aa transmembrane domain and a 134 aa cytoplasmic domain. The function of VSIG8 is not clear. |
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TMPJ-01033
|
NXPH1 Protein, Human, Recombinant (His)
NXPH1,Neurexophilin-1,NPH1
|
Human
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HEK293 Cells
|
|
Neurexophilin-1 (NXPH1) is a member of Neurexophilin family. NXPH1 consist of 271 amino acis. It contains a 21 amino acid signal peptide, 86 amino acid propeptide, and 164 amino acid mature protein. NXPH1 is expressed in subpopulations of neurons within the cerebral cortex, cerebellum and olfactory bulb that are thought to be inhibitory interneurons. In humans, NXPH2 and NXPH3 are most similar to NXPH1, sharing 84% and 64% aa identity within the mature region, respectively. By contrast, NXPH4 d... |
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TMPJ-00056
|
AG-2 Protein, Human, Recombinant (His)
HPC8,AG2,AG-2,hAG-2,Anterior Gradient Protein 2 Homolog,AGR2...
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Human
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HEK293 Cells
|
|
Anterior Gradient 2 (AGR2) is an 18-21 kDa member of the PDI family of enzymes. AGR2 is widely expressed in secretory cells, such as small intestine goblet, prostate epithelium, enteroendocrine cells, and multiple carcinoma cell types. AGR2 forms transient disulfide linkages with molecules destined for secretion, possibly aiding protein folding. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of E... |
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TMPJ-01224
|
FGFRL1 Protein, Human, Recombinant (His)
FGFR5,FGFR-5,FGFRL1,FGFR-Like Protein,FHFR,FGF Homologous Fa...
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Human
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HEK293 Cells
|
|
Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consists of a 354 amino acid extracellular domain (ECD) with 3 Ig-like C2-type domains, a 21 amino acid transmembrane segment, and a 134 amino acid cytoplasmic domain. FGFR1 expressed in various tissues, preferentially in cartilaginous tissues and pancreas. It highly expressed in the liver, kidney, heart, brain and skeletal muscle, weakly exp... |
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TMPK-00217
|
Siglec-15 Protein, Human, Recombinant (His & Avi)
Siglec15,CD33 molecule-like 3,HsT1361,CD33L3,CD33 antigen-li...
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Human
|
HEK293 Cells
|
|
Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.. |
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TMPK-01295
|
Siglec-15 Protein, Cynomolgus, Recombinant (His & Avi)
CD33 molecule-like 3,Siglec15,CD33 antigen-like 3,HsT1361,SI...
|
Cynomolgus
|
HEK293 Cells
|
|
Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates. Siglec-15 Protein, Cynomolgus, Recombinant (His & Avi) is expressed in HEK293 mam... |
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TMPK-01111
|
LILRB1/CD85j/ILT2 Domain1 & 2 Protein, Human, Recombinant (His)
CD85J,XXbac-BCX85G21.4,LILRB1,ILT2,ILT2FLJ37515,LIR...
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Human
|
HEK293 Cells
|
|
LILRB1, also known as CD85j and IL-T2, is a 110 kDa transmembrane glycoprotein in the LILR immunoregulatory protein family. Mature human LILRB1 consists of a 438 amino acid (aa) extracellular domain (ECD) with 4 tandem Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 4 inhibitory ITIM motifs.LILRB1 is a receptor for class I MHC antigens. LILRB1/CD85j/ILT2 Domain1 & 2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The p... |
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TMPK-00296
|
LILRA1/LIR-6/CD85i Protein, Human, Recombinant (His & Avi)
CD85i,LIR6MGC126563,LIR6,LILRA1,LIR-6
|
Human
|
HEK293 Cells
|
|
LILRA1, also known as CD85i and LIR-6, is an approximately 70 kDa variably glycosylated transmembrane protein that regulates immune cell activation. Mature human LILRA1 consists of a 445 amino acid (aa) extracellular domain (ECD) with 4 Ig-like domains, a 21 aa transmembrane segment, and a 7 aa cytoplasmic tail. LILRA1 may act as receptor for class I MHC antigens. LILRA1/LIR-6/CD85i Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted m... |
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TMPJ-00052
|
Leptin Protein, Mouse, Recombinant
OB,Obesity Factor,OBS,LEP,Obese Protein,Leptin
|
Mouse
|
E. coli
|
|
Leptin is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance. Leptin functions via signaling pathways involving OB-R in hypothalamus. Animal models have revealed the influence of Leptin in reducing body weight and regulating blood glucose level. When mutations are introduced in obese gene, mice with impaired function of leptin are massively obese and in high risk of diabetes. Leptin deficiency reduces metablic rate. Leptin defici... |
|
TMPK-01110
|
LILRB1/CD85j/ILT2 Protein, Human, Recombinant (aa 116-461, His)
ILT-2,XXbac-BCX85G21.4,MIR7,ILT2FLJ37515,LILRB1,LIR...
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Human
|
HEK293 Cells
|
|
LILRB1, also known as CD85j and IL-T2, is a 110 kDa transmembrane glycoprotein in the LILR immunoregulatory protein family. Mature human LILRB1 consists of a 438 amino acid (aa) extracellular domain (ECD) with 4 tandem Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 4 inhibitory ITIM motifs.LILRB1 is a receptor for class I MHC antigens. LILRB1/CD85j/ILT2 Protein, Human, Recombinant (aa 116-461, His) is expressed in HEK293 mammalian cells with C-His tag. The p... |
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TMPK-00297
|
LILRA1/LIR-6/CD85i Protein, Human, Recombinant (His & Avi), Biotinylated
LILRA1,LIR-6,LIR6MGC126563,LIR6,CD85i
|
Human
|
HEK293 Cells
|
|
LILRA1, also known as CD85i and LIR-6, is an approximately 70 kDa variably glycosylated transmembrane protein that regulates immune cell activation. Mature human LILRA1 consists of a 445 amino acid (aa) extracellular domain (ECD) with 4 Ig-like domains, a 21 aa transmembrane segment, and a 7 aa cytoplasmic tail. LILRA1 may act as receptor for class I MHC antigens. LILRA1/LIR-6/CD85i Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. T... |
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TMPJ-00218
|
SLAMF6 Protein, Human, Recombinant (His & Avi), Biotinylated
CD352,SLAM Family Member 6,Activating NK Receptor,NTB-A,KALI...
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Human
|
HEK293 Cells
|
|
SLAM Family Member 6 (SLAMF6) is a 60 kD single-pass type I membrane protein that belongs to the SLAM subgroup of the CD2 family. Human SLAMF6/ NTB-A contains a 205 amino acid extracellular domain (ECD) with one Ig-like V-set and one Ig-like C2-set domain, a 21 amino acid transmembrane segment and an 84 amino acid cytoplasmic domain, with two immunoreceptor tyrosine-based switch motifs. SLAMF6 is a homodimer. SLAMF6 can interact with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. Pho... |
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TMPJ-00552
|
LILRB2/CD85d/ILT4 Protein, Human, Recombinant (Avi & His), Biotinylated
Leukocyte Immunoglobulin-Like Receptor 2,Monocyte/Macrophage...
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Human
|
HEK293 Cells
|
|
Members of the immunoglobulin-like transcript (ILT) family are activating and inhibitory immunoreceptors whose genes are located same locus that encodes killer cell Ig-like receptors (KIR). Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2 (LIR-2) is a type I transmembrane protein. LIR-2 is expressed primarily on monocytes and dendritic cells (DC). Human LIR-2 is produced as a 598 amino acino acid precursor including a 21 aa signal sequence, a 440 aa extracellular domain (ECD), a 21 aa... |
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TMPJ-00610
|
hFcRL1 Protein, Mouse, Recombinant (His)
FcR-like protein 1,BXMAS1-like protein 1,mIFGP1,Fc receptor ...
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Mouse
|
HEK293 Cells
|
|
Mouse Fc receptor-like protein 1 (FCRL1) is a single-pass type I membrane protein. It is expressed in B-cells at the various stages of differentiation. Mouse FCRL1 consists of a 203 amino acid (aa) extracellular domain (ECD) with two Ig‑like domains, a 21 aa transmembrane segment, and a 103 aa cytoplasmic domain with two immunotyrosine activation motifs (ITAMs). FCRL1 is likely not a receptor for immunoglobulin. It may function as an activating coreceptor in B-cells and B-cells differentiation. |
|
TMPK-00295
|
LILRA2/CD85h/ILT1 Protein, Human, Recombinant (His & Avi), Biotinylated
LIR7,ILT-1,ILT1,LILRA2,CD85h,ILT1CD85H
|
Human
|
HEK293 Cells
|
|
LILRA2, also known as ILT1, CD85h, and LIR7, is an approximately 70 kDa variably glycosylated transmembrane protein that regulates immune cell activation. Mature human LILRA2 consists of a 426 amino acid (aa) extracellular domain (ECD) with 4 Ig-like domains, a 21 aa transmembrane segment, and a 13 aa cytoplasmic tail. LILRA2 is part of the innate immune responses against microbial infection. LILRA2/CD85h/ILT1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian... |
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TMPK-00294
|
LILRA2/CD85h/ILT1 Protein, Human, Recombinant (His & Avi)
LILRA2,ILT1,LIR7,CD85h,ILT1CD85H,ILT-1
|
Human
|
HEK293 Cells
|
|
LILRA2, also known as ILT1, CD85h, and LIR7, is an approximately 70 kDa variably glycosylated transmembrane protein that regulates immune cell activation. Mature human LILRA2 consists of a 426 amino acid (aa) extracellular domain (ECD) with 4 Ig-like domains, a 21 aa transmembrane segment, and a 13 aa cytoplasmic tail. LILRA2 is part of the innate immune responses against microbial infection. LILRA2/CD85h/ILT1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-... |
|
TMPK-00318
|
Nectin-3 Protein, Human, Recombinant (His & Avi)
PVRR3,PRR3,CDw113,FLJ90624,PVRL3,PPR3,CD113
|
Human
|
HEK293 Cells
|
|
The Nectin family has at least four members (Nectin-1‑4), all of which show alternate splicing, a transmembrane (TM) region (except for Nectin-1 gamma), and three extracellular Ig-domains. Nectins are highly homologous to the human receptor for poliovirus, and as such, have been alternatively-named poliovirus receptor-related proteins. They do not, however, appear to bind poliovirus. Nectin-3 (also named PRR3, CD113, and PVRL3) is an 83 kDa, type I TM glycoprotein. Its precursor is 549 amino aci... |
|
TMPK-00344
|
LILRB5/CD85c Protein, Human, Recombinant (His & Avi)
CD85C,LIR8,LIR-8
|
Human
|
HEK293 Cells
|
|
LILRB5, also known as CD85c andLIR-8, belongs to a family of transmembrane glycoproteins that negatively regulate immune cell activation. Mature human LIR-8 consists of a 435 amino acid (aa) extracellular domain with four Ig-like domains, a 21 aa transmembrane segment, and a 111 aa cytoplasmic domain with two immunoreceptor tyrosine-based inhibitory motifs (ITIM). LILRB5 may act as receptor for class I MHC antigens. LILRB5/CD85c Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mamm... |
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TMPK-01296
|
Siglec-15 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
CD33 molecule-like 3,CD33L3,Siglec15,SIGLEC-15,CD33 antigen-...
|
Cynomolgus
|
HEK293 Cells
|
|
Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates. Siglec-15 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated is expressed... |
|
TMPK-00345
|
LILRB5/CD85c Protein, Human, Recombinant (His & Avi), Biotinylated
LIR-8,CD85C,LIR8
|
Human
|
HEK293 Cells
|
|
LILRB5, also known as CD85c andLIR-8, belongs to a family of transmembrane glycoproteins that negatively regulate immune cell activation. Mature human LIR-8 consists of a 435 amino acid (aa) extracellular domain with four Ig-like domains, a 21 aa transmembrane segment, and a 111 aa cytoplasmic domain with two immunoreceptor tyrosine-based inhibitory motifs (ITIM). LILRB5 may act as receptor for class I MHC antigens. LILRB5/CD85c Protein, Human, Recombinant (His & Avi), Biotinylated is expressed ... |
|
TMPK-00185
|
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His & Avi)
ILT11CD85f,LIR-9,ILT11,LILRA5,CD85,LILRB7,LIR9,ILT-11,CD85f
|
Human
|
HEK293 Cells
|
|
The leukocyte immunoglobulin-like receptors (LILR) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIRs). Human LILRA5, also known as ILT11, LIR-9, and CD85f, consists of a 227 amino acid (aa) extracellular domain (ECD), a 21 aa transmembrane segment, and a 10 aa cytoplasmic tail. LILRA5 may play a role in triggering innate immune responses. Does not seem to play a role for any class I MHC a... |
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TMPJ-00120
|
NKp80/KLRF1 Protein, Human, Recombinant (His)
Lectin-like receptor F1,C-type lectin domain family 5 member...
|
Human
|
HEK293 Cells
|
|
Killer cell lectin-like receptor subfamily F member 1 (KLRF1) is known as NKp80. Human NKp80, a member of the C-type lectin family of proteins (1 - 3), is 231 aa in length with a 38 amino acid (aa) cytoplasmic region, a 21 aa transmembrane region, and a 172 aa extracellular domain (ECD). The protein strongly expressed in peripheral blood leukocytes and spleen, with weaker expression in lymph node and adult liver, and no expression detected in bone marrow, thymus, and fetal liver. Its' function i... |
|
TMPK-00231
|
Siglec-15 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
CD33 molecule-like 3,Siglec15,CD33L3,HsT1361,CD33 antigen-li...
|
Mouse
|
HEK293 Cells
|
|
Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates. Siglec-15 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylate... |
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TMPK-00607
|
LILRB4/CD85k/ILT3 SR & Domain 2 Protein, Human, Recombinant (His & Avi), Biotinylated
ILT-3,ILT3,LILRB4,HM18,LIR5,CD85K
|
Human
|
HEK293 Cells
|
|
LILRB4,also known as CD85k and LIR-5, ILT3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB4/CD85k... |
|
TMPK-01312
|
LILRB4/CD85k/ILT3 Protein, Cynomolgus, Recombinant (His)
LIR5,CD85K,HM18,LILRB4,ILT3,ILT-3
|
Cynomolgus
|
HEK293 Cells
|
|
LILRB4,also known as CD85k and LIR-5, ILT3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB4/CD85k... |
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TMPK-00086
|
ICOS Protein, Human, Recombinant (aa 21-134, His)
CRP-1,ICOS,AILIM,CVID1,CD278,MGC39850
|
Human
|
HEK293 Cells
|
|
Inducible co-stimulator (ICOS), also called AILIM (activiation-inducible lymphocyte immunomediatory molecule) and CRP-1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. Human ICOS is a homodimeric type I transmembrane protein consisting of 199 amino acids (aa) with a putative 20 aa signal sequence, a 121 aa extracellular domain, a 23 aa transmembrane region, and a 35 aa cytoplasmic domain. ICOS Pro... |
|
TMPK-00507
|
TREM2 Protein, Cynomolgus, Recombinant (His)
TREM2,Trem2a,PLOSL2,TREM-2,Trem2c,Trem2b
|
Cynomolgus
|
HEK293 Cells
|
|
TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a 35 kDa type I transmembrane member of the TREM family and Ig superfamily. Mature human TREM-2 consists of a 156 amino acid (aa) extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail. TREM-2 forms a receptor signaling complex with TYROBP which mediates signaling and cell activation following ligand binding (PubMed:10799849). Acts as a receptor for amyloid-beta prote... |
|
TMPK-00608
|
LILRB4/CD85k/ILT3 Domain 1 Protein, Human, Recombinant (His & Avi), Biotinylated
CD85K,HM18,ILT-3,ILT3,LILRB4,LIR5
|
Human
|
HEK293 Cells
|
|
LILRB4,also known as CD85k and LIR-5, ILT-3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT-3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB4/CD8... |
|
TMPK-00606
|
LILRB4/CD85k/ILT3 Domain 1+hinge Protein, Human, Recombinant (His & Avi), Biotinylated
LIR5,HM18,CD85K,ILT-3,LILRB4,ILT3
|
Human
|
HEK293 Cells
|
|
LILRB4,also known as CD85k and LIR-5, ILT3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB4/CD85k... |
|
TMPK-00603
|
LILRB4/CD85k/ILT3 Protein, Human, Recombinant (hFc)
ILT-3,CD85K,HM18,ILT3,LIR5,LILRB4
|
Human
|
HEK293 Cells
|
|
LILRB4,also known as CD85k and LIR-5, ILT3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB4/CD85k... |
|
TMPK-00605
|
LILRB4/CD85k/ILT3 Domain 1 Protein, Human, Recombinant (His & Avi)
LILRB4,ILT-3,HM18,LIR5,CD85K,ILT3
|
Human
|
HEK293 Cells
|
|
LILRB4,also known as CD85k and LIR-5, ILT-3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT-3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB4/CD8... |
|
TMPK-00601
|
LILRB4/CD85k/ILT3 Protein, Human, Recombinant (His & Avi)
ILT3,ILT-3,HM18,LILRB4,CD85K,LIR5
|
Human
|
HEK293 Cells
|
|
LILRB4,also known as CD85k and LIR-5, ILT-3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT-3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB4/CD8... |
|
TMPK-00604
|
LILRB4/CD85k/ILT3 Domain 1+hinge Protein, Human, Recombinant (His & Avi)
HM18,ILT3,LIR5,CD85K,ILT-3,LILRB4
|
Human
|
HEK293 Cells
|
|
LILRB4,also known as CD85k and LIR-5, ILT3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB4/CD85k... |
|
TMPK-00602
|
LILRB4/CD85k/ILT3 Protein, Human, Recombinant (His & Avi), Biotinylated
ILT-3,LIR5,LILRB4,HM18,ILT3,CD85K
|
Human
|
HEK293 Cells
|
|
LILRB4,also known as CD85k and LIR-5, ILT3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB4/CD85k... |
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TMPJ-00136
|
MBL2 Protein, Human, Recombinant (His)
Collectin-1,Mannose-Binding Lectin,COLEC1,Mannan-Binding Pro...
|
Human
|
HEK293 Cells
|
|
Mannose-Binding Protein C (MBP-C) belongs to the Collectin family of innate immune defense proteins. MBL binds to an array of carbohydrate patterns on pathogen surfaces. Collectin family members share common structural features: a cysteine rich amino-terminal domain, a collagen-like region, an α-helical coiled-coil neck domain and a carboxy terminal C-type Lectin or carbohydrate recognition domain (CRD). MBL homotrimerizes to form a structural unit joined by N-terminal disulfide bridges. These h... |
|
TMPJ-00189
|
TIM-3/KIM-3/HAVCR2 Protein, Cynomolgus, Recombinant (His)
HAVCR2,Tim-3,TIM3,T cell immunoglobulin and mucin domain3
|
Cynomolgus
|
HEK293 Cells
|
|
T cell immunoglobulin and mucin domain 3 is a member of the TIM family of immune regulating molecules. Mature cynomolgus TIM3 consists of a 182 amino acid (aa)extracellular domain (ECD), a 21 aa transmembrane segment, and a 78 aa cytoplasmic tail. TIM3 is up-regulated on several populations of activated myeloid cells (macrophage, monocyte, dendritic cell, microglia, mast cell) and T cells (Th1, CD8+, NK, Treg). Its binding to Galectin9 induces a range of immunosuppressive functions which enhance... |
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TMPJ-01452
|
Notch 1 Protein, Mouse, Recombinant (aa 18-526, His)
mT14,Neurogenic locus notch homolog protein 1,Motch A,Notch ...
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Mouse
|
HEK293 Cells
|
|
Mouse Notch1 is a 300 kDa type I transmembrane glycoprotein and it functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Mouse Notch1 is synthesized as a 2531 amino acid (aa) precursor that contains an 18 aa signal sequence, a 1707 aa extracellular domain (ECD) with 36 EGFlike repeats and three Lin12/notch repeats, a 21 aa transmembrane segment and a 785 aa cytoplasmic domain that contains six ankyrin repeats, a glutamine-rich domain ... |
|
TMPJ-01206
|
Sting Protein, Human, Recombinant (Sumo & His)
TMEM173,Mediator of IRF3 activation,Stimulator of interferon...
|
Human
|
E. coli
|
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Stimulator of Interferon Gene(Sting,TMEM173) belongs to the TMEM173 family. STING is 379 amino acids (aa) in length. It contains an N-terminal cytoplasmic region (aa 1-20), four transmembrane segments (aa 21-173), and a C-terminal cytoplasmic domain (aa 174-379). It ubiquitously expressed in skin endothelial cells, alveolar type 2 pneumocytes, bronchial epithelium and alveolar macrophagesand. Its subunit structure associated with the MHC-II complex and Interacts with DDX58/RIG-I, MAVS and SSR2,... |
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TMPJ-00176
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B7-H4 Protein, Human, Recombinant (hFc & Avi), Biotinylated
B7H4T-cell costimulatory molecule B7x,FLJ22418,B7XPRO1291,B7...
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Human
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HEK293 Cells
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B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins. Mature human B7-H4 consists of a 235 amino acid (aa) extracellular domain (ECD) with two Ig-like V-type domains, a 21 aa transmembrane segment, and a 2 aa cytoplasmic tail. It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine ... |
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TMPJ-01199
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BTN2A1 Protein, Human, Recombinant (His)
BT2.1,BTN2A1,Butyrophilin subfamily 2 member A1,BTF1
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Human
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HEK293 Cells
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Butyrophilin 2A1 (BTN2A1) is an approximately widely expressed and variably glycosylated type I transmembrane glycoprotein. Mature human Butyrophilin 2A1 consisits of a 220 amino acid (aa) extracellular domain with two immunoglobulin-like domains, a 21 aa transmembrane segment, and a 258 aa cytoplasmic domain. Alternative splicing generates additional isoforms of human Butyrophilin 2A1 that lack the first Ig like domain or transmembrane segment as well as isoforms with substitutions and deletion... |
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TMPJ-00225
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Siglec-15 Protein, Mouse, Recombinant (His)
Siglec-15,Sialic acid-binding Ig-like lectin 15,CD33L3,CD33 ...
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Mouse
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HEK293 Cells
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Human Siglec-15 is a transmembrane glycoprotein in the Siglec family. Siglecs are type I transmembrane proteins where the NH3+-terminus is in the extracellular space and the COO−-terminus is cytosolic. Each Siglec contains an N-terminal V-type immunoglobulin domain (Ig domain) which acts as the binding receptor for sialic acid. These lectins are placed into the group of I-type lectins because the lectin domain is an immunoglobulin fold. All Siglecs are extended from the cell surface by C2-type I... |
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TMPJ-00055
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Podoplanin Protein, Mouse, Recombinant (hFc)
T1-alpha,PA2.26 antigen,T1A,Podoplanin,T1-α,Glycoprotein 38,...
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Mouse
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HEK293 Cells
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Podoplanin belongs to the podoplanin family, also known as Glycoprotein 38. Podoplanin is synthesized as a 172 amino acid (aa) precursor with a 22 aa signal sequence, a 119 aa extracellular domain (ECD), a 21 aa transmembrane region, and a short, 10 aa cytoplasmic tail. Detected at high levels in lung and brain, at lower levels in kidney, stomach, liver, spleen and esophagus, and not detected in skin and small intestine. Expressed in epithelial cells of choroid plexus, ependyma, glomerulus and ... |
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TMPJ-01361
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Siglec-8 Protein, Human, Recombinant (mFc)
CD329 antigen,Siglec-8,SAF2SAF-2,CDw329,Siglec8,SAF-2,SAF2
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Human
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HEK293 Cells
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Siglec-8 is also known as SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L and sialic acid binding Ig like lectin 8, is an approximately 75 kDa transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Siglec-8 is expressed on eosinophils, basophils, and mast cells, and it shows a binding preference for the carbohydrate 6-O sulfated sLex. At the tissue level, Siglec-8 mRNA was found to be most highly expressed in lung, PBMCs, spleen, and kidney. Mature human Siglec-8 c... |
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TMPJ-01086
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CD244 Protein, Mouse, Recombinant (His)
NK cell type I receptor protein 2B4,Natural killer cell rece...
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Mouse
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HEK293 Cells
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Natural killer cell receptor 2B4 (2B4/CD244)is a 66 kDa type I transmembrane glycoprotein in the SLAM subgroup of the CD2 protein family. SLAM family proteins have an extracellular domain (ECD) with two or four Ig-like domains and at least two cytoplasmic immunoreceptor tyrosine-based switch motifs (ITSMs). 2B4 interacts with CD48, while other SLAM family proteins interact in a homophilic manner. The mouse 2B4 cDNA encodes a 397 amino acid (aa) precursor that includes a 19 aa signal sequence, a ... |
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TMPY-01926
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S100A10 Protein, Human, Recombinant (His)
ANX2L,S100 calcium binding protein A10,p10,CLP11,MGC111133,G...
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Human
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E. coli
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S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S1 proteins have been implicated in a variety of int... |
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TMPY-00351
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FGFR2 Protein, Human, Recombinant (beta IIIc, His)
fibroblast growth factor receptor 2,TK14,FGFR2 Protein,CD332...
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Human
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HEK293 Cells
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FGFR2 Protein, Human, Recombinant (beta IIIc, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.2 kDa and the accession number is P21802-21. |
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