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Targets Recommended: Others

248

抑制剂 & 化合物

19

天然产物

2

化合物库

2

TargetMol 试剂盒

540

重组蛋白

6

同位素标记化合物

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Cat. No. Product Name
L9700 内质网应激化合物库

193 compounds
193 个内质网应激相关的化合物集合,可用于高通量和高内涵筛选;
L8500 HIF-1化合物库

1336 compounds
1336 个HIF-1相关小分子的独特集合,可用于缺血性疾病、癌症等相关领域的药物开发和药理研究;

化合物库

内质网应激化合物库
Cat.No: L9700
Compounds: 193
HIF-1化合物库
Cat.No: L8500
Compounds: 1336
Cat. No. Product Name Form Specificity Of Inhibition
C0051 Penicillin-Streptomycin Solution (100×), Sterile

青霉素-链霉素双抗溶液(100×),灭菌

Solution in bottle
C0052 Penicillin-Streptomycin-Amphotericin B Solution (100×), Sterile

青霉素-链霉素-两性霉素B三抗溶液(100×),灭菌

Solution in bottle

TargetMol 试剂盒

青霉素-链霉素双抗溶液(100×),灭菌
Cat.No: C0051
青霉素-链霉素-两性霉素B三抗溶液(100×),灭菌
Cat.No: C0052
Cat. No. Product Name Target Signaling Pathways
T50029 G6Pase catalytic subunit 1 inhibitor 1

2-((2,2-Dibenzylhydrazineylidene)methyl)pyridine,2-[(1E)-(dibenzylhydrazin-1-ylidene)methyl]pyridine

Others Others
2-((2,2-Dibenzylhydrazineylidene)methyl)pyridine (2-[(1E)-(dibenzylhydrazin-1-ylidene)methyl]pyridine) 是一种杂环化合物。它可以抑制单胺氧化酶,导致体内单胺水平升高;也可以抑制腺苷脱氨酶,导致体内腺苷水平升高;还可以可以增加某些神经递质的活性,包括血清素和多巴胺。
TP1056 Phosphorylase Kinase β-Subunit Fragment (420-436)

Phosphorylase Kinase β-Subunit(420-436),Phosphorylase Kinase β-Subunit Fragment 420-436

Phosphorylase Kinase β-Subunit Fragment (420-436) is a peptide fragment (430-436) derived from the β-Subunit of phosphorylase kinase. Phosphorylase kinase, a serine/threonine-specific protein kinase, plays a crucial role in the activation of glycogen phosphorylase for the release of glucose-1-phosphate from glycogen[1].
T9541 CTB

Cholera Toxin B subunit

Epigenetic Reader Domain Chromatin/Epigenetic
CTB (Cholera Toxin B subunit) 是一种 p300 组蛋白乙酰转移酶的激活剂,可诱导 MCF-7 细胞凋亡。
T64772 Morpholino C subunit

Others Others
Morpholino C subunit 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64772。
T83173 Activated T Subunit

Others Others
Activated T Subunit 用于合成可诱导外显子51跳跃的外显子跳跃寡聚物偶联物。该寡聚物偶联物与人类抗肌萎缩蛋白基因中选定靶位点互补,适用于肌肉萎缩症研究。
T64634 Morpholino A subunit

Others Others
Morpholino A subunit 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64634。
T83177 Activated A Subunit

Others Others
Activated A Subunit 适用于合成促进外显子跳跃的寡聚物偶联体。所合成的偶联体与人类抗肌萎缩蛋白基因内特定的序列配对互补,能够有效促进外显子51的跳跃,为肌萎缩疾病研究提供了一种工具。
T64595 Morpholino T subunit

Others Others
Morpholino T subunit 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64595。
T83176 Activated C Subunit

Others Others
Activated C Subunit 用于合成可诱导外显子51跳跃的外显子跳跃寡聚物偶联物。所得寡聚物偶联物与人类抗肌萎缩蛋白基因特定靶位点互补,有助于研究肌肉萎缩症。
T83175 Activated DPG Subunit

Others Others
Activated DPG Subunit 用于合成可诱导外显子 51 跳跃的外显子跳跃寡聚物偶联物。这些偶联物与人抗肌萎缩蛋白基因中选定的靶位点互补,有助于肌肉萎缩症的研究。
T76088 GSK3 Substrate, α, β subunit

GSK3 Substrate, α, β subunit 是糖原合酶激酶-3 (GSK-3) 的肽底物,可用于测量GSK-3活性。
T38889 Thailanstatin A

Others; ADC Cytotoxin Antibody-drug Conjugate/ADC Related; Others
Thailanstatin A 是真核 RNA 剪接抑制剂,IC50为650 nM,通过非共价结合到剪接体的 U2 snRNA 亚复合物的 SF3b 亚单位发挥作用。Thailanstatin A 对多种癌细胞系的抑制显示 nM 级别的 IC50。它与 Trastuzumab 上的赖氨酸结合,可产生“无连接子” ADC。
T22748 DQP 1105

NMDAR Neuroscience
DQP 1105 是一种高效非竞争性NMDA 受体拮抗剂。DQP-1105 抑制含有 GluN2C (IC50:7.0 Μm) 和 GluN2D (IC50:2.7 Μm) 的受体 。 IC50值至少比重组 GluN2B-、GluN2A-、GluA1- 或 GluK2 受体低 50 倍。
T3157 COH29

RNR Inhibitor COH29

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
COH29 (RNR Inhibitor COH29) 是一种口服可用的芳香族取代噻唑,是人类核糖核苷酸还原酶 (RNR) 的抑制剂,具有潜在的抗肿瘤活性。它抑制核糖核苷酸还原酶的IC50为 16 μM。
T7165 Basmisanil

RG1662,RO5186582,巴米沙尼

GABA Receptor Membrane transporter/Ion channel; Neuroscience
Basmisanil (RG1662) 是高度选择性GABAAα5负调节剂,用于治疗与唐氏综合症相关的认知障碍。
T5007 Benproperine phosphate

磷酸苯丙哌林,Blascorid,Pirexyl phosphate

Others; Microtubule Associated Cytoskeletal Signaling; Others
Benproperine phosphate (Pirexyl phosphate) 是一种具有口服活性的,肌动蛋白相关蛋白 2/3 复合亚基 2 (ARPC2) 抑制剂。它通过削弱 Arp2/3 功能来减弱肌动蛋白的聚合反应速率。它可抑制癌细胞迁移和肿瘤转移,有用于治疗止咳的潜力。
T6549 Isepamicin sulfate

Isepamicine (Isepamycin,硫酸异帕米星,Isepamicin Sulphate,Isepacin,sch21420) Sulphate

Antibacterial; Antibiotic Microbiology/Virology
Isepamicin sulfate (sch21420) Sulphate) 是一种广谱氨基糖苷类抗生素,对产生 I 型 6-乙酰转移酶的菌株具有良好的活性,通过靶向细菌 30S 核糖体亚基来抑制细菌蛋白质合成。
T15401 GNE-371

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
GNE-371 是一种选择性人类转录起始因子 TFIID 亚基 1 和转录起始因子 TFIID 亚基 1-like 第二溴结构域的探针。
T14971 CIQ

NMDAR Neuroscience
CIQ 是亚基选择性NMDA 受体增强剂,可作用于NR2C 或NR2D 亚基。
T9230 KM 91104

ATPase Membrane transporter/Ion channel
KM 91104 是一种细胞通透性 V-ATPase 抑制剂,选择性作用于 V-ATPase 的 a3-b2 亚单位。
T12733 Rislenemdaz

CERC-301,MK-0657

iGluR Membrane transporter/Ion channel; Neuroscience
Rislenemdaz (CERC-301) (CERC-301)是 N-methyl-D-aspartate (NMDA) receptor subunit 2B (GluN2B) 的拮抗剂。
TP1485L Calcineurin substrate acetate

Autophagy Autophagy
Calcineurin substrate acetate 来自 cAMP 依赖性蛋白激酶的调节 RII 亚基。
T22192 BMS 195614

BMS614

Retinoid Receptor Metabolism
BMS 195614 (BMS614)是一种选择性的RARα拮抗剂。BMS 195614可以与RARα亚基结合。
T1186L Ifenprodil

RC 61-91,RC-61-91,RC61-91,艾芬地尔,RC 6191

Adrenergic Receptor; NMDAR GPCR/G Protein; Neuroscience
Ifenprodil (RC61-91) 是 NMDA 受体抑制剂,特别是 GluN1(甘氨酸结合 NMDA 受体亚基 1)和 GluN2B(谷氨酸结合 NMDA 受体亚基 2)亚基的抑制剂。此外,它抑制 GIRK 通道并与 α1 肾上腺素能、血清素和 sigma 受体相互作用。
T8572 CL 218872

GABA Receptor Membrane transporter/Ion channel; Neuroscience
CL218872 是口服有活性的苯二氮卓类选择性激动剂,激动含有 α1 亚基的GABAA 受体(Ki:130 nM)。它在体内具有抗惊厥及抗焦虑效果。
T1982 3-AP

NSC663249,Triapine,PAN-811,OCX191

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
3-AP (Triapine) 是一种新型的核糖核苷酸还原酶 M2 亚基抑制剂,也是一种放射致敏剂。
T12758 Ro 25-6981

NMDAR Neuroscience
Ro 25-6981 是一种有效的选择性活性依赖性 NMDA 受体阻滞剂,含有 NR2B 亚基,对克隆受体亚基组合 NR1C/NR2B 和 NR1C/NR2A 的 IC50 分别为 0.009 和 52 μM。 Ro 25-6981 可用于帕金森病的研究。
T12758L Ro 25-6981 Maleate

Ro-25-6981 Maleate,Ro 256981 Maleate

NMDAR Neuroscience
Ro 25-6981 Maleate 是一种具有选择性的 NR2B 亚基特异性 NMDA 受体 拮抗剂,具有抗惊厥抗抑郁活性,可用于研究帕金森和癫痫等神经系统疾病。
T5400 Q203

IAP6,Telacebec

Antibacterial; Antibiotic Microbiology/Virology
Q203 (Telacebec)是一种中氮杂吡啶酰胺。 在培养基中抑制结核分枝杆菌H37Rv 活性的MIC50值为2.7 nM。
T13848 SMARCA-BD ligand 1 for Protac

Epigenetic Reader Domain Chromatin/Epigenetic
SMARCA-BD ligand 1 for Protac 能够与 BAF ATPase 亚基 SMARCA2 结合,可用于 PROTAC 技术,用于降解 SMARCA2。
T3265 Azathramycin

Desmethyl Azithromycin,阿奇霉素 A,6-Demethylazithromycin,去甲基阿奇霉素,Azaerythromycin A,Azaerythromycin

Antibacterial; Antibiotic Microbiology/Virology
Azathramycin (Desmethyl Azithromycin) 是一种可靶向核糖体的抗生素。
T4377 Pimodivir

VX-787

Influenza Virus Microbiology/Virology
Pimodivir (VX-787) 是一种通过口服的甲型流感病毒聚合酶抑制剂,与病毒 PB2 亚基相互作用。
T7870 TCN 201

TCN-201

NMDAR; iGluR Membrane transporter/Ion channel; Neuroscience
TCN 201 是选择性的、有效的,非竞争性的GluN1/GluN2A NMDA 受体拮抗剂,pIC50值为 6.8。与 GluN1/GluN2B NMDA 受体 (pIC50<4.3) 相比,它对 GluN1/GluN2A NMDA 受体具有选择性。
T13411 ZLN024

AMPK Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
ZLN024 是有效的 AMPK 变构激活剂,直接激活重组 AMPK α1β1γ1,AMPK α2β1γ1,AMPK α1β2γ1 和 AMPK α2β2γ1 异源三聚体,EC50分别为 0.42 μM,0.95 μM,1.1 μM 和 0.13 μM。
T2661 TGX-221

TGX221

PI3K PI3K/Akt/mTOR signaling
TGX-221 是一种选择性的、高效的、细胞膜渗透的 PI3K p110β 抑制剂,常用于研究癌症。
T36711 FM19G11

FM19G11,HIF-1alpha/2alpha Inhibitor

HIF Angiogenesis; Chromatin/Epigenetic
FM19G11 是一种低氧诱导因子 (HIF) α-亚基抑制剂(在低氧诱导的荧光素酶试验中 IC50 为 80 nM)。
T9262 MAT2A inhibitor 4

Others; Methionine Adenosyltransferase (MAT) Chromatin/Epigenetic; Others
MAT2A inhibitor 4 是一种甲硫氨酸 S- 腺苷转移酶 -2 催化亚基的抑制剂,可用于研究癌症。
TQ0023 Lorediplon

GABA Receptor Membrane transporter/Ion channel; Neuroscience
Lorediplon 是一种新型催眠药物,作为 GABAA 受体调节剂,在 α1 亚基上具有差异活性,与促进睡眠有关。
T5396 Letermovir

AIC246,MK-8828,莱莫维韦

Others; HCV Protease Microbiology/Virology; Others; Proteases/Proteasome
Letermovir (AIC246) 是一种新型抗 CMV 抑制剂,靶向病毒末端酶,抑制其活性。
T9542 NS3861

AChR Neuroscience
NS3861 是烟碱型乙酰胆碱受体的激动剂,对α3β4 nAChR 具有高亲和力。能够分别与α3β4 (Ki:0.62 nM)、α3β2 (Ki:25 nM)、α4β4 (Ki:7.8 nM)、α4β2 (Ki:55 nM) 结合。
T1894 Idelalisib

艾代拉里斯,GS-1101,CAL-101

PI3K; Autophagy Autophagy; PI3K/Akt/mTOR signaling
Idelalisib (GS-1101) 是 PI3K 催化亚基 p110δ 的小分子抑制剂,IC50为 2.5 nM,对 p110δ 的选择性是 p110α/β/γ 的 40 到 300 倍。
T21824 Sephin1

NSC 65390,IFB-088

Phosphatase Metabolism
Sephin1 (IFB-088) 是 GADD34 (PPP1R15A) 的选择性抑制剂,这是一种应激诱导的蛋白磷酸酶 1 复合物调节亚基,可将 eIF2α 去磷酸化。
T5375 Loreclezole

GABA Receptor Membrane transporter/Ion channel; Neuroscience
Loreclezole 是一种选择性 GABAA 受体调节剂,可作为含有 β2 或 β3 亚基的受体的正变构调节剂,有抗癫痫作用。
T0353 Osalmid

Oxaphenamide,4'-Hydroxysalicylanilide,羟苯水杨胺,柳胺酚

HBV; DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
Osalmid (Oxaphenamide) 是一种利胆药物,通过靶向核糖核苷酸还原酶小亚基 M2 来抑制核糖核苷酸还原酶的活性,IC50值为8.23 μM。
T37088L pep2m aceate

Others Others
pep2m aceate 是 GluR2 亚基 C 端与 N-乙基马来酰亚胺敏感融合蛋白相互作用的肽抑制剂。
T11277 FG 7142

ZK 39106,LSU-65

GABA Receptor Membrane transporter/Ion channel; Neuroscience
FG 7142 (LSU-65) 是一种非选择性苯二氮卓类反向激动剂,对含 α1 亚基的 GABAA 受体具有高亲和力,Ki 为 91 nM。它还调节 GABA 诱导的 GABAA 受体上的氯离子通量,表达 α1 亚基,EC50为 137 nM。它可增加酪氨酸羟基化并导致小鼠大脑皮层中 β-肾上腺素受体的上调。
T79835 Aneratrigine hydrochloride

Sodium Channel Membrane transporter/Ion channel
Aneratrigine hydrochloride 是一种钠通道蛋白9型亚基阻断剂,可用于预防或治疗钠通道阻断剂相关疾病。
T5189 Omadacycline

PTK 0796,Amadacycline

ribosome; Antibacterial; Antibiotic Microbiology/Virology
Omadacycline (Amadacycline) 是一种具有口服活性的氨基甲基环素抗菌剂,是四环素类抗生素。它与 30S 核糖体亚基结合,抑制细菌蛋白质合成。它可用于研究急性细菌性皮肤和皮肤结构感染,感染性肺炎和尿路感染。
T39630 Zandatrigine

NBI-921352,XEN901

Sodium Channel Membrane transporter/Ion channel
Zandatrigine (NBI-921352) 是钠通道蛋白 8 型亚基 α 的阻断剂,可用于癫痫治疗的神经系统病理学研究。
T30188L Atagabalin HCl

PD-0200390 HCl,Atagabalin HCl(223445-75-8 Free base)

Calcium Channel Membrane transporter/Ion channel; Metabolism
Atagabalin HCl 是一种新型电压依赖性钙通道(VDCC)α2δ亚基(1 和 2)配体,会影响慢波睡眠,可用于治疗失眠。

化合物

G6Pase catalytic subunit 1 inhibitor 1
Cat.No: T50029
Synonym: 2-((2,2-Dibenzylhydrazineylidene)methyl)pyridine,2-[(1E)-(dibenzylhydrazin-1-ylidene)methyl]pyridine
Target: Others
Phosphorylase Kinase β-Subunit Fragment (420-436)
Cat.No: TP1056
Synonym: Phosphorylase Kinase β-Subunit(420-436),Phosphorylase Kinase β-Subunit Fragment 420-436
Target:
CTB
Cat.No: T9541
Synonym: Cholera Toxin B subunit
Target: Epigenetic Reader Domain
Morpholino C subunit
Cat.No: T64772
Synonym:
Target: Others
Activated T Subunit
Cat.No: T83173
Synonym:
Target: Others
Morpholino A subunit
Cat.No: T64634
Synonym:
Target: Others
Activated A Subunit
Cat.No: T83177
Synonym:
Target: Others
Morpholino T subunit
Cat.No: T64595
Synonym:
Target: Others
Activated C Subunit
Cat.No: T83176
Synonym:
Target: Others
Activated DPG Subunit
Cat.No: T83175
Synonym:
Target: Others
GSK3 Substrate, α, β subunit
Cat.No: T76088
Synonym:
Target:
Thailanstatin A
Cat.No: T38889
Synonym:
Target: Others, ADC Cytotoxin
DQP 1105
Cat.No: T22748
Synonym:
Target: NMDAR
COH29
Cat.No: T3157
Synonym: RNR Inhibitor COH29
Target: DNA/RNA Synthesis
Basmisanil
Cat.No: T7165
Synonym: RG1662,RO5186582,巴米沙尼
Target: GABA Receptor
Benproperine phosphate
Cat.No: T5007
Synonym: 磷酸苯丙哌林,Blascorid,Pirexyl phosphate
Target: Others, Microtubule Associated
Isepamicin sulfate
Cat.No: T6549
Synonym: Isepamicine (Isepamycin,硫酸异帕米星,Isepamicin Sulphate,Isepacin,sch21420) Sulphate
Target: Antibacterial, Antibiotic
GNE-371
Cat.No: T15401
Synonym:
Target: DNA/RNA Synthesis
CIQ
Cat.No: T14971
Synonym:
Target: NMDAR
KM 91104
Cat.No: T9230
Synonym:
Target: ATPase
Rislenemdaz
Cat.No: T12733
Synonym: CERC-301,MK-0657
Target: iGluR
Calcineurin substrate acetate
Cat.No: TP1485L
Synonym:
Target: Autophagy
BMS 195614
Cat.No: T22192
Synonym: BMS614
Target: Retinoid Receptor
Ifenprodil
Cat.No: T1186L
Synonym: RC 61-91,RC-61-91,RC61-91,艾芬地尔,RC 6191
Target: Adrenergic Receptor, NMDAR
CL 218872
Cat.No: T8572
Synonym:
Target: GABA Receptor
3-AP
Cat.No: T1982
Synonym: NSC663249,Triapine,PAN-811,OCX191
Target: DNA/RNA Synthesis
Ro 25-6981
Cat.No: T12758
Synonym:
Target: NMDAR
Ro 25-6981 Maleate
Cat.No: T12758L
Synonym: Ro-25-6981 Maleate,Ro 256981 Maleate
Target: NMDAR
Q203
Cat.No: T5400
Synonym: IAP6,Telacebec
Target: Antibacterial, Antibiotic
SMARCA-BD ligand 1 for Protac
Cat.No: T13848
Synonym:
Target: Epigenetic Reader Domain
Azathramycin
Cat.No: T3265
Synonym: Desmethyl Azithromycin,阿奇霉素 A,6-Demethylazithromycin,去甲基阿奇霉素,Azaerythromycin A,Azaerythromycin
Target: Antibacterial, Antibiotic
Pimodivir
Cat.No: T4377
Synonym: VX-787
Target: Influenza Virus
TCN 201
Cat.No: T7870
Synonym: TCN-201
Target: NMDAR, iGluR
ZLN024
Cat.No: T13411
Synonym:
Target: AMPK
TGX-221
Cat.No: T2661
Synonym: TGX221
Target: PI3K
FM19G11
Cat.No: T36711
Synonym: FM19G11,HIF-1alpha/2alpha Inhibitor
Target: HIF
MAT2A inhibitor 4
Cat.No: T9262
Synonym:
Target: Others, Methionine Adenosyltransferase (MAT)
Lorediplon
Cat.No: TQ0023
Synonym:
Target: GABA Receptor
Letermovir
Cat.No: T5396
Synonym: AIC246,MK-8828,莱莫维韦
Target: Others, HCV Protease
NS3861
Cat.No: T9542
Synonym:
Target: AChR
Idelalisib
Cat.No: T1894
Synonym: 艾代拉里斯,GS-1101,CAL-101
Target: PI3K, Autophagy
Sephin1
Cat.No: T21824
Synonym: NSC 65390,IFB-088
Target: Phosphatase
Loreclezole
Cat.No: T5375
Synonym:
Target: GABA Receptor
Osalmid
Cat.No: T0353
Synonym: Oxaphenamide,4'-Hydroxysalicylanilide,羟苯水杨胺,柳胺酚
Target: HBV, DNA/RNA Synthesis
pep2m aceate
Cat.No: T37088L
Synonym:
Target: Others
FG 7142
Cat.No: T11277
Synonym: ZK 39106,LSU-65
Target: GABA Receptor
Aneratrigine hydrochloride
Cat.No: T79835
Synonym:
Target: Sodium Channel
Omadacycline
Cat.No: T5189
Synonym: PTK 0796,Amadacycline
Target: ribosome, Antibacterial, Antibiotic
Zandatrigine
Cat.No: T39630
Synonym: NBI-921352,XEN901
Target: Sodium Channel
Atagabalin HCl
Cat.No: T30188L
Synonym: PD-0200390 HCl,Atagabalin HCl(223445-75-8 Free base)
Target: Calcium Channel
Cat. No. Product Name Target Signaling Pathways
T2S1992 Perillartine

Perilla sugar,Peryllartine,紫苏葶,DL-Perillartine

Others; Endogenous Metabolite Metabolism; Others
Perillartine (DL-Perillartine) 是甜味剂,能够激活味觉受体 1 型成员 2 。
T16552 Pleuromutilin

Mutilin 14-glycolate,Drosophilin B,截短侧耳素

Antibacterial; Antibiotic Microbiology/Virology
Pleuromutilin (Drosophilin B) 通过与细菌的 50S 核糖体亚基结合来抑制细菌蛋白质的合成。
T8162 Cannabidivarin

Cannabidivarin,GWP-42006,GWP42006,GWP 42006

GABA Receptor Membrane transporter/Ion channel; Neuroscience
Cannabidivarin (GWP42006) 是一种非拟精神病药大麻素。 它具有缓解多种神经系统疾病 (包括癫痫和自闭症谱系障碍) 的研究潜力。
T2856 (-)-Epicatechin

L-Epicatechin,表儿茶素,Epicatechin,(-)-Epicatechol,表儿茶精

Ferroptosis; COX; Endogenous Metabolite Apoptosis; Immunology/Inflammation; Metabolism; Neuroscience
(-)-Epicatechin (Epicatechin) 是一种 COX-1 的抑制剂,通过阻断 NF-κB 的 p65 亚基的核定位来抑制 IL-1β 诱导的 iNOS 表达。
T6S1657 Paeonolide

Others Others
Paeonolide 是一种广泛存在于 Paeonia 属植物根中的植物糖苷,是骨形成细胞中核心结合因子亚基 α-1 的新型调节剂。
T4839 Ac-Ala-OH

N-Acetylalanine,N-Acetyl-L-alanine,N-乙酰-L-丙氨酸

Others; Endogenous Metabolite Metabolism; Others
Ac-Ala-OH (N-Acetyl-L-alanine) 是鸟嘌呤核苷酸结合蛋白G(I)/G(S)/G(O) γ -2亚基、髓鞘碱性蛋白、GTP-结合核蛋白 Ran、原肌球蛋白 α - 4链、HIV-1 Rev 结合蛋白2、Xaa-Pro 二肽酶、胸腺酶 β -10、肌动蛋白样蛋白3、丙氨酸转氨酶、丝氨酸/苏氨酸蛋白磷酸酶PP1 - β催化亚基、10 kda 热休克蛋白(线粒体)、钙调蛋白和 β -1-syntrophin 的底物。
T0909 Nalidixic acid

萘啶酸,NSC-82174

Topoisomerase; Antibacterial; Antibiotic DNA Damage/DNA Repair; Microbiology/Virology
Nalidixic acid (NSC-82174) 是一种喹诺酮类抗生素,对革兰氏阳性和革兰氏阴性细菌有效。它在较低浓度下有抑菌作用,而在较高浓度下有杀菌作用。它抑制 DNA 促旋酶和拓扑异构酶 IV 的亚基,并可逆地阻止易感细菌中的 DNA 复制。
T13857 (R,S)-Anatabine

Others; AChR Neuroscience; Others
(R,S)-Anatabine 是一种茄科植物中发现的次要烟草生物碱,可用于烟草使用中特定标记物的检测。(R,S)-Anatabine 是α4β2 和 α6/α3β2β4 亚基烟碱乙酰胆碱受体 (nAChRs)激动剂。
T1304 Chlortetracycline hydrochloride

Isphamycin,Chlortetracycline HCl,7-Chlorotetracycline hydrochloride,盐酸金霉素

ribosome; Antibacterial; Antibiotic Microbiology/Virology
Chlortetracycline hydrochloride (Isphamycin) 是一种特异性钙离子载体抗生素, 抑制氨酰 tRNA 结合到核糖体。
T2S1008 Oxysophoridine

Sophoridine N-oxide,氧化槐定碱

Apoptosis; Antioxidant Apoptosis; oxidation-reduction
Oxysophoridine (Sophoridine N-oxide) 是从苦豆子中提取的一种生物碱,具有抗发炎,抗氧化应激和抗凋亡的作用。
T27191 D-Mannuronic Acid

D-Mannuronic Acid is a blocker of the TLR2 and TLR4 downstream signaling pathway. D-Mannuronic Acid effectively inhibits mRNA expression of MyD88 and p65, major subunit of nuclear factor-kappaB.
T15467 Helenalin

Others Others
Helenalin is a selective inhibitor of transcription factor NF-κB by direct targeting of p65. It is an anti-inflammatory sesquiterpene lactone compound with alkylating activity. Through its ability to target the cysteine sulfhydryl groups in the p65 subunit of NF-κB, helenalin effectively inhibits its DNA binding.
T13053 T-2 Toxin

T-2 Mycotoxin

Apoptosis; ROS; DNA/RNA Synthesis Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation
T-2 Toxin (T-2 Mycotoxin) 是饲料和谷物中的各种镰刀菌种产生的真菌次生代谢产物,具有很强的生殖毒性,可诱发多种心血管毒性。T-2 Toxin 是一种抑制肽基转移酶 (60s ribosomal 亚基) 结合和蛋白质合成的抑制剂,通过ROS诱导的细胞凋亡诱导TM4细胞功能障碍,抑制 DNA 和 RNA 的合成,增加肝脏脂质过氧化物的水平。
T36068 Brevetoxin B

Others Others
Brevetoxin B is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. It binds to site 5 on the alpha subunit of voltage-gated sodium channels (IC50 = 15 nM) on neurons at the neuromuscular junction, causing the channel to open irreversibly at potentials more negative than normal, discharging action potentials repetitively. Brevetoxin B is ichthyotoxic at nanomolar concentrations and is responsible for an illness described as neurotoxic shellfish poisoning.
T37055 Cytostatin

Others Others
Cytostatin is a natural antitumor inhibitor of cell adhesion to extracellular matrix, blocking adhesion of B16 melanoma cells to laminin and collagen type IV in vitro (IC50s = 1.3 and 1.4 μg/ml, respectively) and B16 cells metastatic activity in mice. It induces apoptosis of FS3 mouse fibrosarcoma cells (IC50 = 3.1 μg/ml). Cytostatin potently and selectively inhibits protein phosphatase 2A (PP2A; IC50 = 29 nM against the catalytic subunit), while having no effect against PP1, PP2B, or PP5.
TN1009 Epimagnolin B

NF-κB; NO Synthase; Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation; NF-κB
Epimagnolin B 是一种双环氧木质素,分离自木兰中。它能够抑制 LPS 激活的小胶质细胞中 NO 的产生。它具有抗过敏以及抗炎作用。
TN4490 Manassantin B

ERK; BCL; p38 MAPK; TNF; NF-κB; JNK; STAT; Antifection Apoptosis; JAK/STAT signaling; MAPK; Microbiology/Virology; NF-κB; Stem Cells
Manassantin B is a potent inhibitor of NF-κB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-κB. It also possesses anti-EBV lytic replication activity. Manassantin B inhibits interleukin-6-induced signal transducer and activator of transcription 3 activation in Hep3B cells, it has potential as a potent anti-inflammatory drug for use in pathological processes such as sepsis or acute lung injury. Manassantin B exerts antifibrotic activity in HSC-T6 cells, in pa...
T75540 Ipomoeassin F

Others Others
Ipomoeassin F 是一种高效且具有选择性的内质网(ER)蛋白转位抑制剂,它通过作用于ER膜上的Sec61复合物(Sec61α)的成孔亚基来实现其功能。此化合物能特异性抑制SARS-CoV-2蛋白在ER膜上的转位,同时阻碍分泌蛋白和I型跨膜蛋白(TMP)的ER转运,但对III型TMP的转运不产生影响。
T36749 Herboxidiene

Others Others
Herboxidiene is a polyketide originally isolated from S. chromofuscus that has diverse biological activities.[1],[2,][3],[4],[5] It inhibits growth of HeLa S3, SK-MEL-2, PC3, A549, and EBC-1 cells with GI50 values ranging from 7.4 to 62 nM.3 Herboxidiene is cytostatic against human umbilical vein endothelial cells (HUVECs; (IC50 = 26 nM)) and inhibits VEGF-induced invasion and tube formation of serum-starved HUVECs in a concentration-dependent manner, indicating antiangiogenic activity.[4] Herbo...

天然产物

Perillartine
Cat.No: T2S1992
Synonym: Perilla sugar,Peryllartine,紫苏葶,DL-Perillartine
Target: Others, Endogenous Metabolite
Pleuromutilin
Cat.No: T16552
Synonym: Mutilin 14-glycolate,Drosophilin B,截短侧耳素
Target: Antibacterial, Antibiotic
Cannabidivarin
Cat.No: T8162
Synonym: Cannabidivarin,GWP-42006,GWP42006,GWP 42006
Target: GABA Receptor
(-)-Epicatechin
Cat.No: T2856
Synonym: L-Epicatechin,表儿茶素,Epicatechin,(-)-Epicatechol,表儿茶精
Target: Ferroptosis, COX, Endogenous Metabolite
Paeonolide
Cat.No: T6S1657
Synonym:
Target: Others
Ac-Ala-OH
Cat.No: T4839
Synonym: N-Acetylalanine,N-Acetyl-L-alanine,N-乙酰-L-丙氨酸
Target: Others, Endogenous Metabolite
Nalidixic acid
Cat.No: T0909
Synonym: 萘啶酸,NSC-82174
Target: Topoisomerase, Antibacterial, Antibiotic
(R,S)-Anatabine
Cat.No: T13857
Synonym:
Target: Others, AChR
Chlortetracycline hydrochloride
Cat.No: T1304
Synonym: Isphamycin,Chlortetracycline HCl,7-Chlorotetracycline hydrochloride,盐酸金霉素
Target: ribosome, Antibacterial, Antibiotic
Oxysophoridine
Cat.No: T2S1008
Synonym: Sophoridine N-oxide,氧化槐定碱
Target: Apoptosis, Antioxidant
D-Mannuronic Acid
Cat.No: T27191
Synonym:
Target:
Helenalin
Cat.No: T15467
Synonym:
Target: Others
T-2 Toxin
Cat.No: T13053
Synonym: T-2 Mycotoxin
Target: Apoptosis, ROS, DNA/RNA Synthesis
Brevetoxin B
Cat.No: T36068
Synonym:
Target: Others
Cytostatin
Cat.No: T37055
Synonym:
Target: Others
Epimagnolin B
Cat.No: TN1009
Synonym:
Target: NF-κB, NO Synthase, Prostaglandin Receptor
Manassantin B
Cat.No: TN4490
Synonym:
Target: ERK, BCL, p38 MAPK, TNF, NF-κB, JNK, STAT, Antifection
Ipomoeassin F
Cat.No: T75540
Synonym:
Target: Others
Herboxidiene
Cat.No: T36749
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPJ-00154 IL-15RA Protein, Mouse, Recombinant (hFc, Human Cells)

sIL-15 receptor subunit α,Il15ra,Interleukin-15 rec...

Mouse HEK293 Cells
Mouse interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il...
TMPH-00002 PSMD3 Protein, Human, Recombinant (His)

PSMD3,26S proteasome regulatory subunit S3,26S prot...

Human P. pastoris (Yeast)
PSMD3 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 63 kDa; 70 kDa, reducing conditions and the accession number is O43242.
TMPH-00226 ATPase subunit g Protein, Bovine, Recombinant (His & Myc)

ATP synthase subunit g, mitochondrial,ATP5MG,ATP sy...

Bovine E. coli
ATPase subunit g Protein, Bovine, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.7 kDa and the accession number is Q28852.
TMPH-00495 Lutropin subunit beta Protein, Canine, Recombinant (His)

Luteinizing hormone subunit beta,Lutropin subun...

Canine E. coli
Lutropin subunit beta Protein, Canine, Recombinant (His) is expressed in E. coli.
TMPH-00283 Lutropin subunit beta Protein, Bovine, Recombinant (His)

LHB,Lutropin subunit beta,Lutropin beta chain,Lutei...

Bovine E. coli
Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. Lutropin subunit beta Protein, Bovine, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.0 kDa and the accession number is P04651.
TMPH-00322 Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His)

Snaclec rhodocytin subunit beta,Aggretin beta chain...

Calloselasma rhodostoma P. pastoris (Yeast)
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLCgamma2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostom...
TMPH-00208 Serotype 3 fimbrial subunit Protein, Bordetella pertussis, Recombinant (His)

fim3,Serotype 3 fimbrial subunit

Bordetella pertussis E. coli
Bordetella pertussis is the causative agent of whooping cough. An essential step in the disease process is the attachment of the bacteria to the ciliated epithelium of the respiratory tract, enabling the organism to resist normal host-clearance mechanisms. It is unclear which bacterial cell surface component are responsible for adherence but the fimbriae of B.pertussis are prime candidates for being involved in this process. Serotype 3 fimbrial subunit Protein, Bordetella pertussis, Recombinant ...
TMPH-00320 Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His)

Rhodoaggretin subunit alpha,Aggretin alpha chain,Sn...

Calloselasma rhodostoma P. pastoris (Yeast)
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodo...
TMPH-00321 Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His & SUMO)

Rhodoaggretin subunit alpha,Aggretin alpha chain,Sn...

Calloselasma rhodostoma E. coli
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodo...
TMPH-00360 DNA polymerase II large subunit Protein, Cenarchaeum symbiosum, Recombinant

Exodeoxyribonuclease large subunit,DNA polymerase I...

Cenarchaeum symbiosum E. coli
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. DNA polymerase II large subunit Protein, Cenarchaeum symbiosum, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 59.0 kDa and the accession number is A0RYM0.
TMPH-00323 Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His & Myc)

Aggretin beta chain,Rhodoaggretin subunit beta,Snac...

Calloselasma rhodostoma E. coli
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLCgamma2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostom...
TMPH-00671 Major curlin subunit Protein, E. coli O157:H7, Recombinant (His)

csgA,Major curlin subunit

E. coli P. pastoris (Yeast)
Curlin is the structural subunit of the curli. Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. Major curlin subunit Protein, E. coli O157:H7, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 14.6 kDa and the accession number is Q93U24.
TMPH-03562 Leukocidin-F subunit/LukF Protein, S. aureus, Recombinant (His & Myc & SUMO)

Gamma-hemolysin, H-gamma-I subunit,Leukocidin-F

Staphylococcus aureus E. coli
Leukocidin causes cytotoxic changes in polymorphonuclear leukocytes. Gamma-hemolysin causes hemolysis in red blood cells. Leukocidin-F subunit/LukF Protein, S. aureus, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 54.0 kDa and the accession number is P31715.
TMPH-02597 C1QA Protein, Mouse, Recombinant (His)

Complement C1q subcomponent subunit A,C1QA

Mouse P. pastoris (Yeast)
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
TMPY-01462 IL-11R alpha/IL-11RA Protein, Human, Recombinant (His)

interleukin 11 receptor subunit alpha,hCG_2011440,C...

Human HEK293 Cells
IL-11R alpha/IL-11RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.6 kDa and the accession number is Q14626-1.
TMPH-00601 CS6 fimbrial subunit B Protein, E. coli, Recombinant (His & SUMO)

CS6 fimbrial subunit B,cssB

E. coli E. coli
CS6 fimbrial subunit B Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-00009 OGT Protein, Human, Recombinant (His & SUMO)

OGT,O-GlcNAc transferase subunit p110,O-linked N-ac...

Human E. coli
OGT Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 62.5 kDa and the accession number is O15294.
TMPY-02447 Shiga toxin II subunit B Protein, E. coli, Recombinant (His)

E. coli E. coli
E. Coli STX2B is a subunit of Stx2. Stx2, together with Stx1, formed a family of related toxins which are known as shiga toxins. Shiga toxins are mainly produced by the bacteria S. dysenteriae and the Shigatoxigenic group of Escherichia coli, which includes serotypes O157:H7, O104:H4, and other enterohemorrhagic E. coli (EHEC). A total of 3222 outbreak cases (including 39 deaths) have been reported in northern Germany in May through June 2011. The outbreak strain was typed as an enteroaggregativ...
TMPY-04874 IL-23 P19/IL23A Protein, Human, Recombinant (hFc)

IL-23A,IL-23,interleukin 23, alpha subunit p19,SGRF...

Human HEK293 Cells
IL-23 P19/IL23A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.4 kDa and the accession number is Q9NPF7.
TMPJ-01099 IL-15RA Protein, Human, Recombinant (hFc, Human Cells)

interleukin-15 receptor subunit α,IL15RA,interleuki...

Human HEK293 Cells
Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-boun...
TMPH-01434 Hemoglobin subunit delta/HBD Protein, Human, Recombinant (GST & His)

HBD,Hemoglobin delta chain,Hemoglobin subunit delta...

Human E. coli
Involved in oxygen transport from the lung to the various peripheral tissues. Hemoglobin subunit delta/HBD Protein, Human, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 47.5 kDa and the accession number is P02042.
TMPY-03441 SAE1 Protein, Human, Recombinant

SUA1,SUMO1 activating enzyme subunit 1,HSPC140,UBLE...

Human Baculovirus Insect Cells
SAE1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 38.6 kDa and the accession number is Q9UBE0.
TMPY-01250 IL-11R alpha/IL-11RA Protein, Mouse, Recombinant (His)

AI314697,Il11ra1,interleukin 11 receptor subunit al...

Mouse HEK293 Cells
IL-11R alpha/IL-11RA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.2 kDa and the accession number is Q64385.
TMPJ-00387 IL-4R alpha Protein, Mouse, Recombinant (hFc)

Soluble IL-4R-alpha,Interleukin-4 receptor subunit ...

Mouse HEK293 Cells
Interleukin-4 receptor subunit alpha(IL-4RA), alos known as Soluble IL-4 receptor subunit alpha, belongs to the type I cytokine receptor family and type 4 subfamily. It expressed in both Th1 and Th2 cells. It functions as receptor for both interleukin 4 and interleukin 13 and couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and chemokine and mucus production at sites of allergic ...
TMPH-01029 CAPN1 Protein, Human, Recombinant (His)

CANPL1,CAPN1,Calpain-1 catalytic subunit,Micromolar...

Human E. coli
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-387' and 'His-409'. CAPN1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 85.9 kDa and the accession number is P07384.
TMPH-01435 Hemoglobin subunit gamma-1/HBG1 Protein, Human, Recombinant (His & Myc)

Hemoglobin gamma-1 chain,Hemoglobin subunit gamma-1...

Human E. coli
Gamma chains make up the fetal hemoglobin F, in combination with alpha chains. Hemoglobin subunit gamma-1/HBG1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 23.0 kDa and the accession number is P69891.
TMPH-01031 CAPN2 Protein, Human, Recombinant (His)

Calpain-2 catalytic subunit,Millimolar-calpain,Calp...

Human E. coli
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs. CAPN2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 82...
TMPY-02260 HEXA Protein, Human, Recombinant (Subunit A, His)

hexosaminidase A (alpha polypeptide),hexosaminidase A (α pol...

Human Baculovirus Insect Cells
HEXA Protein, Human, Recombinant (Subunit A, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.7 kDa and the accession number is AAD13932.1.
TMPJ-01054 PAFAHB Protein, Human, Recombinant (His)

PAFAH Subunit Beta,PAF-AH 30 kDa Subunit,P...

Human E. coli
Platelet-Activating Factor Acetylhydrolase IB Subunit β (PAFAHB) is a cytoplasmic hydrolase. PAFAHB is a member of the GDSL lipolytic enzyme family. It also belongs to Platelet-activating factor acetylhydrolase IB beta/gamma subunits subfamily. Cytosolic PAF-AH IB is formed of three subunits of 45 kDa (alpha), 30 kDa (beta) and 29 kDa (gamma), PAFAHB is a catalytic subunit. PAFAHB inactivates PAF by removing the acetyl group at the sn-2 position.
TMPH-01253 DCTN3 Protein, Human, Recombinant (His & SUMO)

DCTN22,Dynactin complex subunit 22 kDa subunit<...

Human E. coli
Together with dynein may be involved in spindle assembly and cytokinesis. DCTN3 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.3 kDa and the accession number is O75935.
TMPJ-00639 CD123 Protein, Cynomolgus, Recombinant (His)

Interleukin-3 receptor subunit α,IL-3R subunit<...

Cynomolgus HEK293 Cells
CD123 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 50-65 KDa and the accession number is G8F3K3.
TMPJ-00251 IL-3R alpha/CD123 Protein, Mouse, Recombinant (aa 17-331, His)

IL-3 receptor subunit alpha,IL-3R subunit ...

Mouse HEK293 Cells
IL-3R alpha/CD123 Protein, Mouse, Recombinant (aa 17-331, His) is expressed in HEK293 mammalian cells with C-8xHis tag. The predicted molecular weight is 50-65 KDa and the accession number is P26952.
TMPY-00312 Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein/NP Protein (His)

Sec61 α1 subunit (S. cerevisiae),Sec61 alpha 1 ...

EBOV E. coli
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 15.6 kDa and the accession number is X5GXS8.
TMPJ-01424 IL-10R alpha/IL-10RA Protein, Macaca mulatta, Recombinant (His)

IL-10RA,Interleukin-10 receptor subunit 1,IL-10R

Macaca Mulatta HEK293 Cells
Interleukin-10 Receptor alpha (IL-10 R alpha), also known as IL-10 R1, is transmembrane glycoprotein member of the class II cytokine receptor family. Interleukin-10 (IL10) is a key anti-inflammatory cytokine that is produced predominantly by leukocytes including T cells, B cells, monocytes, macrophages, and dendritic cells (DCs), as well as by some epithelial cells. The receptor for IL10 is a heterotetramer complex comprising two IL10Ra (also referred to as IL10R1) molecules and two IL10Rb (also...
TMPH-00838 LAMB1 Protein, Human, Recombinant (His & SUMO)

LAMB1,Laminin-1 subunit beta,Laminin-12 subunit...

Human E. coli
LAMB1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.3 kDa and the accession number is P07942.
TMPH-01602 LAMA5 Protein, Human, Recombinant (His & SUMO)

LAMA5,Laminin subunit alpha-5,Laminin-15 subuni...

Human E. coli
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
TMPH-00801 UreB Protein, Helicobacter pylori, Recombinant (His)

Urease subunit beta,Urea amidohydrolase subunit...

Helicobacter pylori E. coli
Ammonia produced by ureolysis increases the gastric pH thereby providing an environment permissive for colonization of the stomach. UreB Protein, Helicobacter pylori, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 65.7 kDa and the accession number is P69996.
TMPH-00799 UreA Protein, Helicobacter pylori, Recombinant (E. coli, His)

Urea amidohydrolase subunit alpha,ureA,Urease s...

Helicobacter pylori E. coli
Ammonia produced by ureolysis increases the gastric pH thereby providing an environment permissive for colonization of the stomach. UreA Protein, Helicobacter pylori, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 30.5 kDa and the accession number is P14916.
TMPY-04097 IL-11R alpha/IL-11RA Protein, Canine, Recombinant (His)

interleukin 11 receptor subunit α,IL11RA,interleuki...

Canine HEK293 Cells
IL-11R alpha/IL-11RA Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.4 kDa and the accession number is A0A8C0MDY4.
TMPJ-00244 IL-3R alpha/CD123 Protein, Human, Recombinant (aa 19-305, hFc & Avi), Biotinylated

IL-3R subunit α,IL-3RA,Interleukin-3 receptor s...

Human HEK293 Cells
IL-3R alpha/CD123 Protein, Human, Recombinant (aa 19-305, hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 80-100 KDa and the accession number is P26951.
TMPY-00308 Ebola virus EBOV (Sudan ebolavirus, strain Gulu) Nucleoprotein/NP Protein (His)

Sec61 alpha 1 subunit (S. cerevisiae),Sec61 α1 ...

EBOV E. coli
Ebola virus EBOV (Sudan ebolavirus, strain Gulu) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 14.8 kDa and the accession number is A0A2U8KL52.
TMPH-00569 atoD Protein, E. coli, Recombinant (His & Myc)

AA-CoA transferase subunit alpha,Acetyl-CoA:acetoac...

E. coli E. coli
N/A. atoD Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 30.5 kDa and the accession number is P76458.
TMPY-04526 Ebola virus EBOV (Sudan ebolavirus, strain Gulu) Nucleoprotein/NP Protein (aa 361-738, His)

Sec61 α1 subunit (S. cerevisiae),Sec61 alpha 1 ...

EBOV E. coli
Ebola virus EBOV (Sudan ebolavirus, strain Gulu) Nucleoprotein/NP Protein (aa 361-738, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 44.1 kDa and the accession number is A0A2U8KL52.
TMPJ-00326 CD122/IL2RB Protein, Human, Recombinant (aa 27-239, His & Avi), Biotinylated

IL-2R subunit beta,High affinity IL-2 receptor ...

Human HEK293 Cells
Human IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit c...
TMPJ-01120 KPNB1 Protein, Human, Recombinant (His)

Nuclear factor p97,Importin subunit β-1,NTF97,Karyo...

Human E. coli
Importin subunit beta-1(KPNB1) is a member of the importin beta family. KPNB1 contains 1 importin N-terminal domain and 19 HEAT repeats. It is involved in nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. Its functions in nuclear protein import, either in association with an adapter protein, like an importin-alpha subunit, which binds to nuclear localization signals (NLS) in cargo substrates, or by ac...
TMPH-00779 IL-23 P19/IL23A Protein, Guinea Pig, Recombinant (His & Myc)

Interleukin-23 subunit p19,Interleukin-23 subun...

Guinea pig E. coli
Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible fo...
TMPH-00519 StxB Protein, Enterobacteria phage H19B, Recombinant (His)

stxB,Verocytotoxin 1 subunit B,Shiga-like toxin 1 <...

Enterobacteria phage H19B E. coli
The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli.
TMPH-00518 StxB2 Protein, Enterobacteria phage 933W, Recombinant (His & SUMO)

Shiga-like toxin 2 subunit B,Verocytotoxin 2 su...

Enterobacteria phage 933W E. coli
The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli.
TMPH-00800 UreA Protein, Helicobacter pylori, Recombinant (His)

ureA,Urea amidohydrolase subunit alpha,Urease s...

Helicobacter pylori P. pastoris (Yeast)
Ammonia produced by ureolysis increases the gastric pH thereby providing an environment permissive for colonization of the stomach.
TMPY-03396 PFDN2 Protein, Human, Recombinant (His)

PFD2,prefoldin subunit 2

Human E. coli
PFD2, also known as PFDN2, belongs to the prefoldin beta subunit family. PFD2 is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. PFD2 binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. PFD2 also binds to a nascent pol...
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重组蛋白

IL-15RA Protein, Mouse, Recombinant (hFc, Human Cells)
Cat.No: TMPJ-00154
Species: Mouse
Expression System: HEK293 Cells
PSMD3 Protein, Human, Recombinant (His)
Cat.No: TMPH-00002
Species: Human
Expression System: P. pastoris (Yeast)
ATPase subunit g Protein, Bovine, Recombinant (His & Myc)
Cat.No: TMPH-00226
Species: Bovine
Expression System: E. coli
Lutropin subunit beta Protein, Canine, Recombinant (His)
Cat.No: TMPH-00495
Species: Canine
Expression System: E. coli
Lutropin subunit beta Protein, Bovine, Recombinant (His)
Cat.No: TMPH-00283
Species: Bovine
Expression System: E. coli
Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His)
Cat.No: TMPH-00322
Species: Calloselasma rhodostoma
Expression System: P. pastoris (Yeast)
Serotype 3 fimbrial subunit Protein, Bordetella pertussis, Recombinant (His)
Cat.No: TMPH-00208
Species: Bordetella pertussis
Expression System: E. coli
Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His)
Cat.No: TMPH-00320
Species: Calloselasma rhodostoma
Expression System: P. pastoris (Yeast)
Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His & SUMO)
Cat.No: TMPH-00321
Species: Calloselasma rhodostoma
Expression System: E. coli
DNA polymerase II large subunit Protein, Cenarchaeum symbiosum, Recombinant
Cat.No: TMPH-00360
Species: Cenarchaeum symbiosum
Expression System: E. coli
Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His & Myc)
Cat.No: TMPH-00323
Species: Calloselasma rhodostoma
Expression System: E. coli
Major curlin subunit Protein, E. coli O157:H7, Recombinant (His)
Cat.No: TMPH-00671
Species: E. coli
Expression System: P. pastoris (Yeast)
Leukocidin-F subunit/LukF Protein, S. aureus, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-03562
Species: Staphylococcus aureus
Expression System: E. coli
C1QA Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02597
Species: Mouse
Expression System: P. pastoris (Yeast)
IL-11R alpha/IL-11RA Protein, Human, Recombinant (His)
Cat.No: TMPY-01462
Species: Human
Expression System: HEK293 Cells
CS6 fimbrial subunit B Protein, E. coli, Recombinant (His & SUMO)
Cat.No: TMPH-00601
Species: E. coli
Expression System: E. coli
OGT Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-00009
Species: Human
Expression System: E. coli
Shiga toxin II subunit B Protein, E. coli, Recombinant (His)
Cat.No: TMPY-02447
Species: E. coli
Expression System: E. coli
IL-23 P19/IL23A Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04874
Species: Human
Expression System: HEK293 Cells
IL-15RA Protein, Human, Recombinant (hFc, Human Cells)
Cat.No: TMPJ-01099
Species: Human
Expression System: HEK293 Cells
Hemoglobin subunit delta/HBD Protein, Human, Recombinant (GST & His)
Cat.No: TMPH-01434
Species: Human
Expression System: E. coli
SAE1 Protein, Human, Recombinant
Cat.No: TMPY-03441
Species: Human
Expression System: Baculovirus Insect Cells
IL-11R alpha/IL-11RA Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01250
Species: Mouse
Expression System: HEK293 Cells
IL-4R alpha Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00387
Species: Mouse
Expression System: HEK293 Cells
CAPN1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01029
Species: Human
Expression System: E. coli
Hemoglobin subunit gamma-1/HBG1 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01435
Species: Human
Expression System: E. coli
CAPN2 Protein, Human, Recombinant (His)
Cat.No: TMPH-01031
Species: Human
Expression System: E. coli
HEXA Protein, Human, Recombinant (Subunit A, His)
Cat.No: TMPY-02260
Species: Human
Expression System: Baculovirus Insect Cells
PAFAHB Protein, Human, Recombinant (His)
Cat.No: TMPJ-01054
Species: Human
Expression System: E. coli
DCTN3 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01253
Species: Human
Expression System: E. coli
CD123 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-00639
Species: Cynomolgus
Expression System: HEK293 Cells
IL-3R alpha/CD123 Protein, Mouse, Recombinant (aa 17-331, His)
Cat.No: TMPJ-00251
Species: Mouse
Expression System: HEK293 Cells
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein/NP Protein (His)
Cat.No: TMPY-00312
Species: EBOV
Expression System: E. coli
IL-10R alpha/IL-10RA Protein, Macaca mulatta, Recombinant (His)
Cat.No: TMPJ-01424
Species: Macaca Mulatta
Expression System: HEK293 Cells
LAMB1 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-00838
Species: Human
Expression System: E. coli
LAMA5 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01602
Species: Human
Expression System: E. coli
UreB Protein, Helicobacter pylori, Recombinant (His)
Cat.No: TMPH-00801
Species: Helicobacter pylori
Expression System: E. coli
UreA Protein, Helicobacter pylori, Recombinant (E. coli, His)
Cat.No: TMPH-00799
Species: Helicobacter pylori
Expression System: E. coli
IL-11R alpha/IL-11RA Protein, Canine, Recombinant (His)
Cat.No: TMPY-04097
Species: Canine
Expression System: HEK293 Cells
IL-3R alpha/CD123 Protein, Human, Recombinant (aa 19-305, hFc & Avi), Biotinylated
Cat.No: TMPJ-00244
Species: Human
Expression System: HEK293 Cells
Ebola virus EBOV (Sudan ebolavirus, strain Gulu) Nucleoprotein/NP Protein (His)
Cat.No: TMPY-00308
Species: EBOV
Expression System: E. coli
atoD Protein, E. coli, Recombinant (His & Myc)
Cat.No: TMPH-00569
Species: E. coli
Expression System: E. coli
Ebola virus EBOV (Sudan ebolavirus, strain Gulu) Nucleoprotein/NP Protein (aa 361-738, His)
Cat.No: TMPY-04526
Species: EBOV
Expression System: E. coli
CD122/IL2RB Protein, Human, Recombinant (aa 27-239, His & Avi), Biotinylated
Cat.No: TMPJ-00326
Species: Human
Expression System: HEK293 Cells
KPNB1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01120
Species: Human
Expression System: E. coli
IL-23 P19/IL23A Protein, Guinea Pig, Recombinant (His & Myc)
Cat.No: TMPH-00779
Species: Guinea pig
Expression System: E. coli
StxB Protein, Enterobacteria phage H19B, Recombinant (His)
Cat.No: TMPH-00519
Species: Enterobacteria phage H19B
Expression System: E. coli
StxB2 Protein, Enterobacteria phage 933W, Recombinant (His & SUMO)
Cat.No: TMPH-00518
Species: Enterobacteria phage 933W
Expression System: E. coli
UreA Protein, Helicobacter pylori, Recombinant (His)
Cat.No: TMPH-00800
Species: Helicobacter pylori
Expression System: P. pastoris (Yeast)
PFDN2 Protein, Human, Recombinant (His)
Cat.No: TMPY-03396
Species: Human
Expression System: E. coli
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Cat. No. Product Name Target Signaling Pathways
T40376 L-Phenylalanine-15N

L-苯丙氨酸 15N,(S)-2-Amino-3-phenylpropionic acid-15N,L-Phenylalanine-15N

Calcium Channel Membrane transporter/Ion channel; Metabolism
L-Phenylalanine-15N ((S)-2-Amino-3-phenylpropionic acid-15N) 是 15N 标记的 L-Phenylalanine。L-Phenylalanine 是从大肠杆菌中分离出来的一种必需氨基酸。 L-Phenylalanine 广泛用于食品香精和药物的生产。
TMIH-0298 Letermovir-d8

Letermovir-d8 是 Letermovir 的氘代化合物。Letermovir 的 CAS 号为 917389-32-3。Letermovir是一种新型抗 CMV 抑制剂,靶向病毒末端酶,抑制其活性。
TMIH-0105 Baloxavir-d4

Baloxavir-d4 是 Baloxavir 的氘代化合物。Baloxavir 的 CAS 号为 1985605-59-1。Baloxavir 是衍生自前药 Baloxavir marboxil,是流感病毒聚合酶 PA 亚基的一流帽依赖性核酸内切酶抑制剂。它抑制病毒 RNA 的转录和复制,具有强大的抗病毒活性。
TMID-0084 Tigecycline-d9

Tigecycline-d9 是 Tigecycline 的氘代化合物。Tigecycline 的 CAS 号为 220620-09-7。Tigecycline是甘氨酰环素抗生素,对Acinetobacter baumannii(A. baumannii) 的 MIC50和 MIC90分别为 1 和 2 mg/L。它对E. coli(MG1655 菌株) 的平均抑制浓度 (MIC) 约 125 ng/ mL。
T71306 Gemfibrozil-d6

Gemfibrozil-d6 is intended for use as an internal standard for the quantification of gemfibrozil by GC- or LC-MS. Gemfibrozil is a peroxisome proliferator-activated reporter α and PPARγ agonist. In vivo, gemfibrozil reduces serum total cholesterol, triglyceride, and LDL levels in a rat model of high-cholesterol diet-induced hyperlipidemia. Gemfibrozil reduces atherosclerotic plaque area, superoxide production, and expression of the genes encoding the NF-κB subunit p65 and chemokine (C-C) motif l...
TMID-0286 Rifaximin-d6

Rifaximin-d6 是 Rifaximin 的氘代化合物。Rifaximin 的 CAS 号为 80621-81-4。Rifaximin是一种胃肠道选择性抗生素,与细菌 DNA 依赖性 RNA 聚合酶的 β 亚基结合,抑制细菌 RNA 合成。与革兰氏阴性菌(MIC:8-50 毫克/毫升)相比,它对革兰氏阳性菌株(MIC:0.03-5 毫克/毫升)的敏感性更高。

同位素标记化合物

L-Phenylalanine-15N
Cat.No: T40376
Synonym: L-苯丙氨酸 15N,(S)-2-Amino-3-phenylpropionic acid-15N,L-Phenylalanine-15N
Target: Calcium Channel
Letermovir-d8
Cat.No: TMIH-0298
Synonym:
Target:
Baloxavir-d4
Cat.No: TMIH-0105
Synonym:
Target:
Tigecycline-d9
Cat.No: TMID-0084
Synonym:
Target:
Gemfibrozil-d6
Cat.No: T71306
Synonym:
Target:
Rifaximin-d6
Cat.No: TMID-0286
Synonym:
Target:
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