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Search Results for " nucleoside "

Targets Recommended: Nucleoside Antimetabolite/Analog Others

1757

抑制剂 & 化合物

63

天然产物

1

化合物库

32

重组蛋白

12

同位素标记化合物

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Cat. No.	Product Name
L1720	核苷类化合物库		334 compounds
	334 种核苷类化合物，包括核苷酸、核苷酸类似物及衍生物等，适用于抗病毒、抗肿瘤、抗真菌、抗抑郁等药物的研发；

化合物库

核苷类化合物库

Cat.No: L1720

Compounds: 334

Cat. No.	Product Name	Target	Signaling Pathways
T39334	Remdesivir nucleoside monophosphate	Others	Others
	Remdesivir nucleoside monophosphate, a metabolite of Remdesivir, is a potent antiviral compound with nucleoside analogue characteristics. It exhibits effective antiviral activity against both SARS-CoV and MERS-CoV.
T19485	Nucleoside-Analog-1	Others	Others
	Nucleoside-Analog-1 is a 4′-Azidocytidine analogue, used to against Hepatitis C virus replication.
T24385	L-Acosamine nucleoside	Others	Others
	L-Acosamine nucleoside has antiviral activity against HIV and HSV-1.
T25759	L-Ristosamine nucleoside	Others	Others
	L-Ristosamine nucleoside shows antiviral activity.
T19486	Nucleoside-Analog-2	Others	Others
	Nucleoside-Analog-2 is a 4'-Azidocytidine analogue, used to against Hepatitis C virus (HCV) replication.
T6065	Triciribine VD-0002,Tricyclic nucleoside,NSC 154020,曲西立滨,API-2,TCN	Akt; HIV Protease; DNA/RNA Synthesis	Cell Cycle/Checkpoint; Cytoskeletal Signaling; DNA Damage/DNA Repair; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Triciribine (NSC-154020) 是一种 DNA 合成抑制剂，也抑制 Akt 和 HIV-1/2，IC50分别为 130 nM 和 0.02-0.46 μM。
TNU1281	P-2'-deoxyribose 6-(β-D-2-Deoxyribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one,P-Nucleoside	Others	Others
	P-2'-deoxyribose (P-Nucleoside) 是一种脱氧核糖，广泛存在于生物体内。
T76096	Purine nucleoside phosphorylase	Others	Others
	Purine nucleoside phosphorylase 是嘌呤代谢中的关键酶，参与嘌呤挽救途径。Purine nucleoside phosphorylase 缺乏导致 T 细胞功能受损。在无机正磷酸盐作为第二底物的存在下，Purine nucleoside phosphorylase 催化核糖和脱氧核糖核苷的糖苷键断裂，生成嘌呤碱和核糖（脱氧核糖）-1-磷酸。
T75409	Nucleoside hydrolase (IAGNH)	Others	Others
	Nucleoside hydrolase (IAGNH)为一种糖苷酶，专门催化核苷中N-糖苷键的裂解，从而促进核碱基与Rib的循环利用。
T9727	2'-Fluoro-2'-Deoxyadenosine	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	2′-Deoxy-2′-fluoroadenosine 可用于合成2 ' -脱氧-2 ' -氟修饰的寡核苷酸。它能被大肠杆菌嘌呤核苷磷酸化酶（PNP）有效地分解成毒性物 2-氟腺嘌呤，对表达大肠杆菌 PNP 的肿瘤表现出良好的体内活性。
T8354	Triazavirin	Nucleoside Antimetabolite/Analog; Influenza Virus; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Triazavirin 是一种核酸的核苷类似物和抗病毒剂，通过抑制病毒 RNA 和 DNA 的合成以及基因组片段的复制而起作用。在流感传播阶段，它可作为保护剂。
T13621	CNDAC hydrochloride	Nucleoside Antimetabolite/Analog; Others; Drug Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	CNDAC hydrochloride 是一种核苷类似物，是沙帕他滨的代谢物。
T7351	3-Methylcytidine	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	3-Methylcytidine 是一种尿核苷，作为四种不同类型癌症的生物标志物：肺癌、胃癌、结肠癌和乳腺癌。
T0297	Clofarabine Clofarex,氯法拉滨,克罗拉滨,Evoltra,Clolar	Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis; Autophagy	Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Clofarabine (Clofarex) 是一种核糖核苷酸还原酶抑制剂，IC50值为65 nM。它是核苷类似物，可用于癌症研究。
T12399	Peldesine BCX 34	Nucleoside Antimetabolite/Analog; HIV Protease	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	Peldesine (BCX 34) 是一种有效的、竞争性的、可逆的和口服活性的嘌呤核苷磷酸化酶抑制剂。 Peldesine 抑制 T 细胞增殖，IC50 为 800 nM。 Peldesine 可用于皮肤 T 细胞淋巴瘤、牛皮癣和 HIV 感染的研究。
T9726	2’-OMe-Guanosine	Apoptosis; Nucleoside Antimetabolite/Analog	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	2'-O-Methylguanosine 是一种修饰核苷，是tRNA 上的核苷在 tRNA 鸟苷-2’-o-甲基转移酶作用下产生的。2'-O-Methylguanosine 具有一定的促凋亡作用。
T7491	6-O-Methyl Guanosine	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	6-O-Methyl Guanosine 是一种修饰核苷，有抑制恶性干皮病细胞系的集落形成能力。
T15235	Enocitabine	Nucleoside Antimetabolite/Analog; HCV Protease; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	Enocitabine 是一种核苷类似物，抑制 DNA 复制剂。Enocitabine 抑制人巨细胞病毒的复制，显示出抗白血病和抗病毒活性。
T38237	2′-O-Methylcytidine	Nucleoside Antimetabolite/Analog; HCV Protease	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	2'-O-Methylcytidine 是 2'-代核苷，可抑制 HCV 复制。它在体外抑制 NS5B 催化的 RNA 合成，其抑制方式是与底物核苷三磷酸竞争。
T13659	DMTr-LNA-5MeU-3-CED-phosphoramidite	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	DMTr-LNA-5MeU-3-CED-phosphoramidite 是核苷的衍生物。
T3658	Trifluridine/tipiracil hydrochloride mixture Trifluridine-tipiracil hydrochloride mixture,TAS102,TAS-102,TAS 102	Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Trifluridine/tipiracil hydrochloride mixture (TAS-102) 是一种新型口服组合药物，含有摩尔比为 2:1 的曲氟尿苷(TFT) 和盐酸替吡嘧啶 (TTP)。它主要通过抑制胸苷酸合酶 (TS) 和掺入 DNA 来显示抗肿瘤活性。
T9103	BVDV-IN-1	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	BVDV-IN-1 是一种牛病毒性腹泻病毒 (BVDV) 的非核苷抑制剂 (NNI)，EC50 为 1.8 μM。它直接与 BVDV RdRp 的疏水口袋结合，对耐 NNI 氨基硫脲 (TSC) 的 BVDV 具有抗病毒活性。
T38238	2'-Deoxy-2'-fluorocytidine	Nucleoside Antimetabolite/Analog; Influenza Virus	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	2'-Deoxy-2'-fluorocytidine 是一种核苷类似物，可有效抑制刚果出血热病毒的复制。2'-Deoxy-2'-fluorocytidine 与 T705 的协同作用会增强对CCHFV 复制的抵抗效力。
T1404	Stavudine d4T,Sanilvudine,BMY-27857,NSC 163661,司他夫定	Apoptosis; Nucleoside Antimetabolite/Analog; HIV Protease; NOD-like Receptor (NLR); Reverse Transcriptase; Autophagy	Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Stavudine (BMY-27857) 是一种口服活性核苷逆转录酶抑制剂，还抑制线粒体 DNA 的复制，具有抗HIV-1和HIV-2的活性。它降低 NLRP3 炎症小体激活，调节淀粉样 β 自噬，诱导细胞凋亡。
T7518	Deoxycytidine triphosphate trisodium salt 2'-脱氧胞苷-5'-三磷酸三钠盐,2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI	Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis; Endogenous Metabolite; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) 是可用于 DNA 合成的核苷三磷酸，可用于实时荧光定量 PCR、cDNA 合成和 DNA 测序。
T1307	Carmofur HCFU,卡莫氟	Nucleoside Antimetabolite/Analog; Virus Protease; SARS-CoV; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Carmofur (HCFU) 是 5-氟尿嘧啶的衍生物，是一种抗肿瘤药物。它是一种酸性神经酰胺酶抑制剂，用于治疗乳腺癌和结直肠癌。它抑制 SARS-CoV-2主要蛋白酶，还抑制 Vero E6 细胞 SARS-CoV-2，EC50为 24.3 μM。
T8648	6-AZATHYMINE	Nucleoside Antimetabolite/Analog; Influenza Virus; DNA/RNA Synthesis; Antibacterial	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	6-Azathymine 是胸腺嘧啶的 6-氮类似物，是 D-3-氨基异丁酸酯-丙酮酸氨基转移酶抑制剂，具有抗菌和抗病毒活性，可抑制DNA 的生物合成。
T36756	DMT-dG(ib) Phosphoramidite	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	DMT-dG(ib) Phosphoramidite 可用于 DNA 的合成。
T40686	Tiazofurin NSC 286193,Riboxamide,噻唑呋林	Dehydrogenase	Metabolism
	Tiazofurin (NSC-286193) 是一种合成的核苷类似物，显示出抗肿瘤活性。它在细胞内合成为 tiazole-4-carboxamide adenine dinucleotide (TAD)，TAD 可有效抑制 IMP 脱氢酶。
T38236	2′-Deoxy-2′-fluoroguanosine	Nucleoside Antimetabolite/Analog; Influenza Virus	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	2′-Deoxy-2′-fluoroguanosine 是一种核苷类似物，有效抑制流感病毒，抑制A 型和B 型流感病毒的EC90值 <0.35 μM。2′-Deoxy-2′-fluoroguanosine 显著抑制流感病毒在上呼吸道中的复制，从而改善鼻腔炎症和发烧。
T19464	N6,N6-Dimethyladenosine N6,N6-二甲基腺苷	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	N6,N6-Dimethyladenosine 是存在于牛分枝杆菌 tRNA 中的一种修饰核糖核苷
T4061	LY2334737	Nucleoside Antimetabolite/Analog; Others; Virus Protease	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	LY2334737 是一种具有口服活性的 Gemcitabine 的前药，也是核苷类似物。它抑制肠道病毒 A71 感染，有抗病毒和抗癌活性。
T16911	Sorivudine BV-araU,索立夫定	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Sorivudine (BV-araU) 是口服有效的，嘧啶核苷抗代谢药物。它的抗病毒活性来自某些 DNA 病毒中存在的特定胸苷激酶选择性转化为核苷酸，从而反过来会干扰病毒 DNA 合成。
T2366	Tipiracil hydrochloride MA-1 hydrochloride,盐酸替吡嘧啶	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Tipiracil hydrochloride (MA-1 hydrochloride) 是一种胸苷磷酸化酶抑制剂，是抗癌候选药物 TAS-102 中的活性成分之一，用于癌症研究。
T38958	DMT-2′Fluoro-dU Phosphoramidite 2'-F-dU Phosphoramidite	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) 可用于核苷修饰。
T10066	2',5'-Dideoxyadenosine	Adenylyl cyclase; Adrenergic Receptor; AChR	GPCR/G Protein; Neuroscience
	2',5'-Dideoxyadenosine 是一种非竞争性腺苷酸环化酶抑制剂，通过结合 P 位点，IC50为 3 µM。它是核苷类似物，在心脏中发挥强大的抗肾上腺素作用。
T7621	6-Thioinosine 6-Mercaptopurine riboside,6-疏基嘌呤核苷,6TI	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	6-Thioinosine (6TI) 是一种嘌呤抗代谢物，是抗脂肪形成剂，能降低PPAR γ和C/EBPα及其目标基因 aP2、CD36、LPL 和 LXRα 的 mRNA 水平。
T1120	Dacarbazine Imidazole Carboxamide,达卡巴嗪,DTIC-Dome	Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Dacarbazine (DTIC-Dome) 是一种抗肿瘤剂，对黑色素瘤具有显着的活性。
T6446	Clevudine L-FMAU,克拉夫定,Levovir	HBV; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Clevudine (Levovir) 是一种非自然 L-构型的核苷类似物，是一种与聚合酶结合的非竞争性抑制剂，具有较强的抗 HBV 活性，半衰期长，毒性低的特点。
T6603	Nelarabine GW 506U78,Nelzarabine,奈拉滨,506U78	Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Nelarabine (GW 506U78) 是一种嘌呤核苷酸类似物，为DNA 合成抑制剂，对肿瘤细胞的IC50为0.067-2.15 μM，可作用于T 细胞急性淋巴细胞白血病。
T1408	Capecitabine Xeloda,卡培他滨,Capecitibine,Capiibine,RO 09-1978	Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Capecitabine (Capecitibine) 是一种可口服的前药，可由胸苷磷酸化酶催化转变为其活性代谢物 Fluorouracil。
T0251	Gemcitabine 吉西他滨,NSC 613327,LY188011	Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis; Autophagy	Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Gemcitabine (LY188011) 是一种人工合成的胞嘧啶核苷衍生物，一种 DNA 合成抑制剂。Gemcitabine 具有抗肿瘤活性和抗代谢活性。Gemcitabine 可以引起细胞自噬和凋亡。
T0010	6-Mercaptopurine 6-巯基嘌呤,乐疾宁,6-MP,Mercaptopurine,6-巯基嘌呤	Nucleoside Antimetabolite/Analog; Others; Dehydrogenase; Endogenous Metabolite; Autophagy	Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	6-Mercaptopurine (6-MP) 是一种具有免疫抑制特性的抗代谢物抗肿瘤剂。它通过抑制嘌呤代谢来干扰核酸合成，通常与其他药物联合用于白血病的治疗或缓解维持计划。
T0075	Nicorandil SG-75,尼可地尔	Potassium Channel	Membrane transporter/Ion channel
	Nicorandil (SG-75) 是一种有效的钾通道激活剂，靶向血管核苷二磷酸依赖性 K+通道和心脏 ATP 敏感 K+通道 (KATP)。Nicorandil 是一种烟酰胺酯，具有血管舒张和心脏保护作用，并具有治疗心绞痛和缺血性心脏病的潜力。
T1646	Famciclovir 泛昔洛韦,BRL 42810	DNA/RNA Synthesis; HSV	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Famciclovir (BRL 42810) 是一种单纯疱疹病毒核苷类似物 DNA 聚合酶抑制剂。
T6729	Lomibuvir VX-222,VCH-222	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Lomibuvir (VCH-222) (VX-222) 是丙型肝炎病毒 NS5B 聚合酶的一种非核苷变构抑制剂，Kd 值为 17 nM，已证明具有临床疗效。Lomibuvir 抑制 1b/Con1 型 HCV 亚基因组复制子，EC50为 5.2 nM。Lomibuvir 优先抑制延长的 RNA 合成，而非从头合成的 RNA。
T19459	N1-Methylpseudouridine N1-甲基-假尿苷,1-Methylpseudouridine	Others	Others
	N1-Methylpseudouridine (1-Methylpseudouridine) 是一种甲基假尿苷，翻译性能比 5 mC 和 5 mC/N1-Methylpseudouridine 高。通过提高核糖体密度，mRNA 中的 N1-Methylpseudouridine 以 eIF2α 依赖性和独立机制增强翻译。
T16813	RX-3117 fluorocyclopentenylcytosine,TV-1360	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	RX-3117 (fluorocyclopentenylcytosine) 是一种新型的胞苷类似物，在几种癌细胞系中显示出抗癌活性，包括对吉西他滨耐药的变体。
T1378	Tegafur Fluorafur,替加氟,FT-207,NSC 148958,FT 207	Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Tegafur (FT 207) 是一种前药，在肝脏中被细胞色素 P-450 酶逐渐转化为氟尿嘧啶。它是抗代谢物氟尿嘧啶的同源物，具有抗肿瘤活性。
T40192	dGTP 2′-脱氧鸟苷 5′-(四氢三磷酸酯),2'-Deoxyguanosine-5'-triphosphate	Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	dGTP（2'-Deoxyguanosine-5'-triphosphate）作为脱氧核糖核酸（DNA）合成的基本单元，属于鸟苷核苷酸，对8-O-GDP、8-O-dGTP、8-O-GTP及8-O-dGTP的氧化损伤具有高度敏感性。

化合物

Remdesivir nucleoside monophosphate

Cat.No: T39334

Target: Others

Nucleoside-Analog-1

Cat.No: T19485

Target: Others

L-Acosamine nucleoside

Cat.No: T24385

Target: Others

L-Ristosamine nucleoside

Cat.No: T25759

Target: Others

Nucleoside-Analog-2

Cat.No: T19486

Target: Others

Cat.No: T6065

Synonym: VD-0002,Tricyclic nucleoside,NSC 154020,曲西立滨,API-2,TCN

Target: Akt, HIV Protease, DNA/RNA Synthesis

P-2'-deoxyribose

Cat.No: TNU1281

Synonym: 6-(β-D-2-Deoxyribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one,P-Nucleoside

Target: Others

Purine nucleoside phosphorylase

Cat.No: T76096

Target: Others

Nucleoside hydrolase (IAGNH)

Cat.No: T75409

Target: Others

2'-Fluoro-2'-Deoxyadenosine

Cat.No: T9727

Target: Nucleoside Antimetabolite/Analog

Cat.No: T8354

Target: Nucleoside Antimetabolite/Analog, Influenza Virus, DNA/RNA Synthesis

CNDAC hydrochloride

Cat.No: T13621

Target: Nucleoside Antimetabolite/Analog, Others, Drug Metabolite

3-Methylcytidine

Cat.No: T7351

Target: Nucleoside Antimetabolite/Analog

Cat.No: T0297

Synonym: Clofarex,氯法拉滨,克罗拉滨,Evoltra,Clolar

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Autophagy

Cat.No: T12399

Synonym: BCX 34

Target: Nucleoside Antimetabolite/Analog, HIV Protease

2’-OMe-Guanosine

Cat.No: T9726

Target: Apoptosis, Nucleoside Antimetabolite/Analog

6-O-Methyl Guanosine

Cat.No: T7491

Target: Nucleoside Antimetabolite/Analog

Cat.No: T15235

Target: Nucleoside Antimetabolite/Analog, HCV Protease, DNA/RNA Synthesis

2′-O-Methylcytidine

Cat.No: T38237

Target: Nucleoside Antimetabolite/Analog, HCV Protease

DMTr-LNA-5MeU-3-CED-phosphoramidite

Cat.No: T13659

Target: Nucleoside Antimetabolite/Analog

Trifluridine/tipiracil hydrochloride mixture

Cat.No: T3658

Synonym: Trifluridine-tipiracil hydrochloride mixture,TAS102,TAS-102,TAS 102

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Cat.No: T9103

Target: DNA/RNA Synthesis

2'-Deoxy-2'-fluorocytidine

Cat.No: T38238

Target: Nucleoside Antimetabolite/Analog, Influenza Virus

Cat.No: T1404

Synonym: d4T,Sanilvudine,BMY-27857,NSC 163661,司他夫定

Target: Apoptosis, Nucleoside Antimetabolite/Analog, HIV Protease, NOD-like Receptor (NLR), Reverse Transcriptase, Autophagy

Deoxycytidine triphosphate trisodium salt

Cat.No: T7518

Synonym: 2'-脱氧胞苷-5'-三磷酸三钠盐,2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Endogenous Metabolite, Antibiotic

Cat.No: T1307

Synonym: HCFU,卡莫氟

Target: Nucleoside Antimetabolite/Analog, Virus Protease, SARS-CoV, DNA/RNA Synthesis

Cat.No: T8648

Target: Nucleoside Antimetabolite/Analog, Influenza Virus, DNA/RNA Synthesis, Antibacterial

DMT-dG(ib) Phosphoramidite

Cat.No: T36756

Target: DNA/RNA Synthesis

Cat.No: T40686

Synonym: NSC 286193,Riboxamide,噻唑呋林

Target: Dehydrogenase

2′-Deoxy-2′-fluoroguanosine

Cat.No: T38236

Target: Nucleoside Antimetabolite/Analog, Influenza Virus

N6,N6-Dimethyladenosine

Cat.No: T19464

Synonym: N6,N6-二甲基腺苷

Target: Nucleoside Antimetabolite/Analog

Cat.No: T4061

Target: Nucleoside Antimetabolite/Analog, Others, Virus Protease

Cat.No: T16911

Synonym: BV-araU,索立夫定

Target: DNA/RNA Synthesis

Tipiracil hydrochloride

Cat.No: T2366

Synonym: MA-1 hydrochloride,盐酸替吡嘧啶

Target: Nucleoside Antimetabolite/Analog

DMT-2′Fluoro-dU Phosphoramidite

Cat.No: T38958

Synonym: 2'-F-dU Phosphoramidite

Target: Nucleoside Antimetabolite/Analog

2',5'-Dideoxyadenosine

Cat.No: T10066

Target: Adenylyl cyclase, Adrenergic Receptor, AChR

Cat.No: T7621

Synonym: 6-Mercaptopurine riboside,6-疏基嘌呤核苷,6TI

Target: Nucleoside Antimetabolite/Analog

Cat.No: T1120

Synonym: Imidazole Carboxamide,达卡巴嗪,DTIC-Dome

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Cat.No: T6446

Synonym: L-FMAU,克拉夫定,Levovir

Target: HBV, DNA/RNA Synthesis

Cat.No: T6603

Synonym: GW 506U78,Nelzarabine,奈拉滨,506U78

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Cat.No: T1408

Synonym: Xeloda,卡培他滨,Capecitibine,Capiibine,RO 09-1978

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Cat.No: T0251

Synonym: 吉西他滨,NSC 613327,LY188011

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Autophagy

6-Mercaptopurine

Cat.No: T0010

Synonym: 6-巯基嘌呤,乐疾宁,6-MP,Mercaptopurine,6-巯基嘌呤

Target: Nucleoside Antimetabolite/Analog, Others, Dehydrogenase, Endogenous Metabolite, Autophagy

Cat.No: T0075

Synonym: SG-75,尼可地尔

Target: Potassium Channel

Cat.No: T1646

Synonym: 泛昔洛韦,BRL 42810

Target: DNA/RNA Synthesis, HSV

Cat.No: T6729

Synonym: VX-222,VCH-222

Target: HCV Protease

N1-Methylpseudouridine

Cat.No: T19459

Synonym: N1-甲基-假尿苷,1-Methylpseudouridine

Target: Others

Cat.No: T16813

Synonym: fluorocyclopentenylcytosine,TV-1360

Target: Nucleoside Antimetabolite/Analog

Cat.No: T1378

Synonym: Fluorafur,替加氟,FT-207,NSC 148958,FT 207

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Cat.No: T40192

Synonym: 2′-脱氧鸟苷 5′-(四氢三磷酸酯),2'-Deoxyguanosine-5'-triphosphate

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Cat. No.	Product Name	Target	Signaling Pathways
T16674	Pseudouridine	Endogenous Metabolite	Metabolism
	Pseudouridine 是非编码 RNA 中丰富的修饰核苷，通过稳定 RNA 结构增强核糖体 RNA 和的转移 RNA 功能。
T7520	Deoxycytidine triphosphate	Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Deoxycytidine triphosphate 是一种核苷三磷酸，是合成 DNA 的原料，可用于实时荧光定量 PCR、cDNA 合成和 DNA 测序。
T5912	5-Methylcytidine	Endogenous Metabolite	Metabolism
	5-Methylcytidine 是一种位于多种体液中的嘧啶核苷。
T7319	7-Methylguanosine	Nucleoside Antimetabolite/Analog; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	7-Methylguanosine 是一种新型 cNIIIB 核苷酸酶抑制剂，IC50值为 87.8 ± 7.5 µM。
T9605	Sangivamycin BA-90912,桑霉素,NSC 65346	Nucleoside Antimetabolite/Analog; PKC	Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair
	Sangivamycin (NSC-65346) 是蛋白激酶 C (PKC) 的有效抑制剂 (Ki = 10 μM)。 Sangivamycin 对多种人类癌症细胞具有抗增殖活性。
T1591L	Cytidine Cytosine-1-β-D-ribofuranoside,胞苷,Cytosine β-D-riboside	Nucleoside Antimetabolite/Analog; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Cytidine (Cytosine-1-β-D-ribofuranoside) 是一种嘧啶核苷，由通过 β-N1-糖苷键与核糖结合的胞嘧啶组成。它是尿苷的前体，用于 RNA 合成。
T19382	Isoguanine 2-羟基-6-氨基嘌呤,异鸟嘌呤	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Isoguanine 是一种嘌呤碱基，是鸟嘌呤的异构体，可作为有机合成的砌块。
T7514	N2-Methylguanosine 2-甲鳥苷	Nucleoside Antimetabolite/Analog; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	N2-Methylguanosine 是一种修饰核苷，出现在许多 tRNA 的几个特定位点。
T2221	Uridine Uridin,β-Uridine,NSC 20256,尿苷	Others; Endogenous Metabolite	Metabolism; Others
	Uridine (Uridin) 是一种核苷化合物, 由核糖环和尿嘧啶组成, 两者通过β-N1-配糖键链接。
T0853	Adenosine 腺苷,D-Adenosine,Adenine riboside	Apoptosis; Nucleoside Antimetabolite/Analog; Endogenous Metabolite; Autophagy	Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Adenosine (D-Adenosine) 是一种核糖核苷，由与核糖结合的腺嘌呤组成，具有血管扩张、抗心律失常和镇痛作用。
T0437	Inosine INO 495,NSC 20262,肌苷	ROS; Endogenous Metabolite; Adenosine Receptor	GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
	Inosine (NSC-20262) 是由腺苷分解代谢产生的一种内源性嘌呤核苷，是腺苷受体A1R 和A2AR 的激动剂，具有抗炎免疫调节，抗伤害和神经保护作用。
T19083	1-Methylinosine N1-Methylinosine,Inosine, 1-methyl,1-甲基肌苷	Nucleoside Antimetabolite/Analog; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	1-Methylinosine (N1-Methylinosine) 是在真核生物 tRNA 反密码子 3' 位 tRNA 的 37 位上发现的修饰核苷酸，具有代谢物的作用。
T0746	Orotic acid 乳清酸,Vitamin B13,6-Carboxyuracil	Nucleoside Antimetabolite/Analog; Dehydrogenase; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Orotic acid (Vitamin B13) 是一种嘧啶核苷酸和 RNA 生物合成的前体，从线粒体二氢乳清酸脱氢酶 (DHODH) 中释放，通过细胞质 UMP 合酶转化为 UMP。它可引起大鼠肝脂肪变性和肝肿大，是尿素循环异常的常规新生儿筛查中的一种测量指标。
T9086	Deoxythymidine-5'-triphosphate trisodium dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),胸苷-5'-三磷酸三钠盐,脱氧胸苷三磷酸三钠盐,Deoxythymidine-5'-triphosphate (dTTP) trisodium salt	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Deoxythymidine-5'-triphosphate trisodium (Deoxythymidine-5'-triphosphate(dTTP) trisodium salt) 是四种天然脱氧核苷酸之一，用于通过 DNA 聚合酶和逆转录酶生物合成脱氧核糖核酸。
T1188	Mizoribine Bredinin,NSC 289637,咪唑立宾,HE 69	HCV Protease; SARS-CoV; Tyrosinase	Microbiology/Virology; Proteases/Proteasome
	Mizoribine (NSC-289637) 是一种免疫抑制剂，抑制HCVRNA 复制，有抗 HCV 活性，IC50约为 100 μM。它抑制SARS-CoV 复制，对 SARS-CoV Frankfurt-1 和 SARS-CoV HKU39849 的 IC50分别为 3.5 μg/mL 和 16 μg/mL。
T1508	Decitabine Dacogen,NSC 127716,地西他滨,Deoxycytidine,5-Aza-2'-deoxycytidine	Apoptosis; Nucleoside Antimetabolite/Analog; DNA Methyltransferase	Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Decitabine (Deoxycytidine) 是脱氧胞苷类似物，一种 DNA 甲基转移酶抑制剂，具有口服活性。Decitabine 具有抗肿瘤活性和抗代谢活性。Decitabine 诱导细胞周期阻滞和凋亡。
T2218	8-Azaguanine Azaguanine-8,SK 1150,8-氮鸟嘌呤,NSC-749,SF-337	Nucleoside Antimetabolite/Analog; Others; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	8-Azaguanine (SK 1150) 是一种具有潜在抗肿瘤活性的嘌呤类似物。它易于掺入核糖核酸中，干扰正常的生物合成途径，从而抑制细胞生长，可作为抗代谢药。
T1339	5-Azacytidine 阿托胞苷,Azacitidine,NSC 102816,Mylosar,Ladakamycin,5-氮杂胞苷,5-AzaC	Nucleoside Antimetabolite/Analog; DNA Methyltransferase; Antibacterial; Antibiotic; Autophagy	Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; Microbiology/Virology
	5-Azacytidine (Ladakamycin) 是一种胞苷核苷类似物，一种 DNA 甲基化抑制剂，具有特异性。5-Azacytidine 通过降低 DNA 甲基化水平调节基因表达。5-Azacytidine 可以诱导细胞自噬，具有抗肿瘤活性。
T3271	Orotic acid zinc 乳清酸锌二水合物,Orotic acid zinc salt dihydrate,Zinc Orotate	Nucleoside Antimetabolite/Analog; Others; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	Orotic acid zinc (Zinc Orotate) 是一种嘧啶核苷酸和 RNA 生物合成的前体，从线粒体二氢乳清酸脱氢酶 (DHODH) 中释放，通过细胞质 UMP 合酶转化为 UMP。它可引起大鼠肝脂肪变性和肝肿大，是尿素循环异常的常规新生儿筛查中的一种测量指标。
T1272	Cytarabine 阿糖胞苷,Ara-C,Cytosine Arabinoside,Cytosine β-D-arabinofuranoside,Arabinocytidine	Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis; Endogenous Metabolite; Autophagy; HSV	Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Cytarabine (Ara-C) 是一种核苷类似物，一种 DNA 合成抑制剂 (IC50=16 nM)。Cytarabine 可以抑制 DNA 聚合酶，诱导细胞周期阻滞、细胞自噬和凋亡。Cytarabine 具有抗肿瘤活性。
T1506	Vidarabine Adenine Arabinoside,阿糖腺苷,9-β-D-Arabinofuranosyladenine,Vira-A,Arabinosyladenine,Ara-A	Nucleoside Antimetabolite/Analog; Tyrosine Kinases; DNA/RNA Synthesis; Antibiotic; HSV	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Tyrosine Kinase/Adaptors
	Vidarabine (Adenine Arabinoside) 是从链霉菌分离的核苷类抗生素，能抗单纯性疱疹和水痘-带状疱疹病毒。它对 HSV-1 和 HSV-2 的 IC50值分别为 9.3 μg/ml 和 11.3 μg/ml。
T8227	5'-Methylthioadenosine Methylthioadenosine,5-脱氧-5-甲硫腺苷,5'-(Methylthio)-5'-deoxyadenosine,5'-Deoxy-5'-(methylthio)adenosine,5'-S-Methyl-5'-thioadenosine	Endogenous Metabolite	Metabolism
	5'-Methylthioadenosine 是由 S-腺苷蛋氨酸在多胺合成过程中生成的核苷，通过抑制肿瘤细胞增殖、侵袭和诱导细胞凋亡来抑制肿瘤，同时控制肿瘤组织的炎症微环境。
T4456	N4-Acetylcytidine N4-乙酰胞苷,N-Acetylcytidine	Others; Endogenous Metabolite	Metabolism; Others
	N4-Acetylcytidine (N-Acetylcytidine) 是内源性代谢产物的一种。
T13791	N2-methylguanine 6-羟基-2-氨甲基嘌呤	DNA/RNA Synthesis; Endogenous Metabolite; Antibacterial	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	N2-methylguanine (N2-methylguanine) 是一种在人体体液中发现的内源性甲基化核苷，是一种修饰的核苷。
TNU0157	3’-O-Methyl guanosine	Endogenous Metabolite	Metabolism
	核苷衍生物 – 3’-改性核苷：该化合物属于核苷衍生物类，特点是在其3’位置上进行了化学修饰。这种修饰赋予了化合物特殊的生物学活性或增强了其原有功能，常见于药物研发及生物医学研究中。
T20041	2'-Deoxyadenosine 2'-脱氧腺苷,NSC-141848,NSC141848,NSC 141848	Endogenous Metabolite	Metabolism
	2'-Deoxyadenosine (NSC-141848) 是核苷腺苷的一种衍生物，能够与双链 DNA 中的脱氧胸苷配对。
T13499	3-Methyluridine	Endogenous Metabolite	Metabolism
	3-Methyluridine 是一种修饰的细胞 RNA 的核苷(RNA nucleoside)。它通常以 RNA 修饰的形式出现，能够在古菌的 23S rRNA、真细菌的 16S 和 23S rRNA 以及真核核糖体 18S、25S 和 28SRNA 的中检测到。
T38251	L-Uridine	Nucleoside Antimetabolite/Analog; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	L-Uridine 是从Polyporaceae fungus Poria cocos (Schw.)分离得到的正常 RNA 成分中的 D-尿苷的对映异构体，属于一种核苷，可充当核苷磷酸转移酶的磷酸受体。L-Uridine 具有潜在的抗病毒活性。
T4972	2'-Deoxycytidine-5'-diphosphate trisodium dCDP,2'-脱氧胞苷-5'-二磷酸三钠盐	Endogenous Metabolite	Metabolism
	2'-Deoxycytidine-5'-diphosphate trisodium (dCDP) 是内源性代谢产物的一种。
T4715	2'-Deoxyguanosine monohydrate 2'-脱氧鸟苷一水合物,Guanine-2'-deoxyriboside	Others; Endogenous Metabolite	Metabolism; Others
	2'-Deoxyguanosine monohydrate (Guanine-2'-deoxyriboside) 是内源性代谢产物的一种。
T7961	N4-Benzoyl-2′-deoxycytidine N-苯甲酰-2'-脱氧胞苷	Others	Others
	N4-Benzoyl-2′-deoxycytidine 是天然核苷脱氧胞苷（dC）的合成核苷类似物，是一种DNA 聚合酶的竞争性抑制剂。体外研究表明，它可以抑制病毒、细菌和真核细胞的复制。在动物模型中，它也被证明可以抑制肿瘤细胞的生长。
T22218	2'-Deoxyguanosine Deoxyguanosine,Guanine deoxyriboside	Endogenous Metabolite	Metabolism
	2'-Deoxyguanosine (Guanine deoxyriboside) 是一种嘌呤核苷，可被2'-dG-II家族的成员识别。2'-Deoxyguanosine 与衰老、突变和致癌有关，可被分子氧氧化。
TMO2681	Xanthosine 9-Beta-D-Ribofuranosylxanthine,黄嘌呤核苷,Xanthine riboside	Others; Endogenous Metabolite	Metabolism; Others
	Xanthosine (9-Beta-D-Ribofuranosylxanthine) 是黄嘌呤核苷，它能够提高山羊和牛的乳腺干细胞数量和产奶量。
T1709	2'-Deoxyinosine Guanine deoxyriboside,Deoxyinosine,2'-脱氧肌苷	Others; Endogenous Metabolite	Metabolism; Others
	2'-Deoxyinosine (Guanine deoxyriboside) 具有抑制人癌细胞株生长的活性，并发现其与嘌呤核苷磷酸化酶缺乏有关。
TQ0193	N2,N2-Dimethylguanosine N2,N2-二甲基鸟苷	Endogenous Metabolite	Metabolism
	N2,N2-Dimethylguanosine 是尿核苷，是 tRNA 的初级代谢产物。
T7457	5-Methyl-2'-deoxycytidine 5-Methyldeoxycytidine,5-甲基-2'-脱氧胞苷,5MedCyd	DNA Methyltransferase; Endogenous Metabolite	Chromatin/Epigenetic; Metabolism
	5-Methyl-2'-deoxycytidine (5MedCyd) 是嘧啶核苷，当掺入到单链 DNA 中时，可以顺式作用以从头发出信号。
T2752	2'-Deoxyadenosine monohydrate	Others; Endogenous Metabolite	Metabolism; Others
	2'-Deoxyadenosine monohydrate 是化学合成中的砌块，是一种脱氧核糖核苷。
T6523	Guanosine 鸟苷,DL-Guanosine,Vernine,Guanozin	Endogenous Metabolite; HSV	Metabolism; Microbiology/Virology
	Guanosine (DL-Guanosine) 是由鸟嘌呤与核糖环组成的一种核苷，两者之间由 β-N9-配糖键相连，具有抗HSV 的活性。
T7548	1-Methylguanosine 1-甲基鸟苷,N1-Methylguanosine,1-甲基鸟酐	Endogenous Metabolite	Metabolism
	1-Methylguanosine (N1-Methylguanosine) 是 RNA 降解产生的甲基化核苷，可作为肿瘤标志物。
T2993	Cordycepin 3'-Deoxyadenosine,虫草素	MMP; TNF; Antibacterial; Antibiotic; Autophagy	Apoptosis; Autophagy; Microbiology/Virology; Proteases/Proteasome
	Cordycepin (3'-Deoxyadenosine) 是一种核苷衍生物，在类风湿性关节炎滑膜成纤维细胞中，剂量依赖性抑制 IL-1β 诱导的 MMP-1和 MMP-3表达。它也抑制细菌的腺苷激酶从而抗结核分枝杆菌。
T5282	5-Methyluridine Ribothymidine,5-甲基尿甙,Thymine riboside	Others; Endogenous Metabolite	Metabolism; Others
	5-Methyluridine (Thymine riboside) 是发现于人体液中的内源性甲基化核苷。
T7004	Tubercidin 结核菌素,杀结核菌素,Sparsomycin A,7-Deazaadenosine	Influenza Virus; DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Tubercidin (Sparsomycin A) 是从Streptomyces tubercidicus 得到的抗生素，抑制粪链球菌生长的IC50值为 0.02 μM。它是腺苷磷酸化酶的弱抑制剂，并干扰腺苷和 AMP 的磷酸化。它有抗病毒作用。
T13539	Allopurinol riboside	Others; Endogenous Metabolite; Parasite; Drug Metabolite	Metabolism; Microbiology/Virology; Others
	Allopurinol riboside 是别嘌醇的代谢产物，具有抗寄生虫作用。 Allopurinol riboside 竞争性抑制嘌呤核苷磷酸化酶对肌苷的作用，Ki 为 277 μM。
T2812	ATP disodium salt hydrate ATP disodium,ATP disodium salt,Adenosine disodium triphosphate,三磷酸腺苷二钠盐	Others; Endogenous Metabolite	Metabolism; Others
	ATP disodium salt hydrate (Adenosine disodium triphosphate) 是体内能量储存和代谢的重要物质，为代谢提供能量，同时在细胞中作为辅酶发挥作用。同时，它是也是免疫和炎症中重要的内源性信号分子。
T64911	Blasticidin S HCl	Antibiotic	Microbiology/Virology
	Blasticidin S HCl 是从 Streptomyces griseochromogenes 中分离的肽基核苷类抗生素 (antibiotic)，主要通过干扰核糖体中肽键的形成从而抑制原核细胞和真核细胞蛋白的合成。
T6220	Nicotinamide riboside chloride 烟酰胺核糖氯酸盐,烟酰胺核苷	Sirtuin; Endogenous Metabolite	Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
	Nicotinamide riboside Chloride 是维生素 B3 的来源，可以增强氧化代谢并防止高脂肪饮食诱导的代谢异常。它是具有口服活性的 NAD+的前体，增加 NAD+水平并激活SIRT1和SIRT3，可用于研究阿尔茨海默氏病的认知退化。
TNU0052	Nebularine 9-(beta-D-Ribofuranosyl)-9H-purine	Apoptosis	Apoptosis
	Nebularine (9-(beta-D-Ribofuranosyl)-9H-purine)，是一种嘌呤核苷类似物，具有广谱的抗肿瘤活性，针对惰性淋巴恶性肿瘤并诱导凋亡。Nebularine的抗癌机制依赖于抑制DNA合成。
T4897	Inosine-5'-triphosphate trisodium salt ITP,肌苷-5'-三磷酸三钠盐,三磷酸肌苷三钠盐,Inosine 5'-triphosphate trisodium salt	Others; Endogenous Metabolite	Metabolism; Others
	Inosine-5'-triphosphate trisodium salt (ITP) 是三磷酸核苷，能够作为 ATPases 和 GTPases 的底物。
T0853L	Adenosine 5'-monophosphate monohydrate 5'-AMP,腺苷-5'-单磷酸一水合物,5'-AMP monohydrate,5'-Adenylic acid	AMPK; Adenosine Receptor; HSV	Chromatin/Epigenetic; GPCR/G Protein; Microbiology/Virology; Neuroscience; PI3K/Akt/mTOR signaling
	Adenosine 5'-monophosphate monohydrate (5'-AMP) 是一种核苷酸，用作 RNA 中的单体。它是一个腺苷 A1受体激动剂，对HSV-1和HSV-2具有显著的抗病毒活性。
T4718	Uridine 5'-monophosphate Uridylic acid,尿苷5-单磷酸,UMP,Uridine phosphate,Uridine 5'-phosphoric acid,5'-Uridylic acid	Others; Endogenous Metabolite	Metabolism; Others
	Uridine 5'-monophosphate (Uridylic acid) 是一种单磷酸盐形式的尿嘧啶核苷酸，能够由从头途径或体内核苷酸和核酸的降解产物获得，是哺乳动物乳中的主要核苷酸类似物。
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天然产物

Cat.No: T16674

Target: Endogenous Metabolite

Deoxycytidine triphosphate

Cat.No: T7520

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Endogenous Metabolite

5-Methylcytidine

Cat.No: T5912

Target: Endogenous Metabolite

7-Methylguanosine

Cat.No: T7319

Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite

Cat.No: T9605

Synonym: BA-90912,桑霉素,NSC 65346

Target: Nucleoside Antimetabolite/Analog, PKC

Cat.No: T1591L

Synonym: Cytosine-1-β-D-ribofuranoside,胞苷,Cytosine β-D-riboside

Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite

Cat.No: T19382

Synonym: 2-羟基-6-氨基嘌呤,异鸟嘌呤

Target: Nucleoside Antimetabolite/Analog

N2-Methylguanosine

Cat.No: T7514

Synonym: 2-甲鳥苷

Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite

Cat.No: T2221

Synonym: Uridin,β-Uridine,NSC 20256,尿苷

Target: Others, Endogenous Metabolite

Cat.No: T0853

Synonym: 腺苷,D-Adenosine,Adenine riboside

Target: Apoptosis, Nucleoside Antimetabolite/Analog, Endogenous Metabolite, Autophagy

Cat.No: T0437

Synonym: INO 495,NSC 20262,肌苷

Target: ROS, Endogenous Metabolite, Adenosine Receptor

1-Methylinosine

Cat.No: T19083

Synonym: N1-Methylinosine,Inosine, 1-methyl,1-甲基肌苷

Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite

Cat.No: T0746

Synonym: 乳清酸,Vitamin B13,6-Carboxyuracil

Target: Nucleoside Antimetabolite/Analog, Dehydrogenase, Endogenous Metabolite

Deoxythymidine-5'-triphosphate trisodium

Cat.No: T9086

Synonym: dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),胸苷-5'-三磷酸三钠盐,脱氧胸苷三磷酸三钠盐,Deoxythymidine-5'-triphosphate (dTTP) trisodium salt

Target: DNA/RNA Synthesis

Cat.No: T1188

Synonym: Bredinin,NSC 289637,咪唑立宾,HE 69

Target: HCV Protease, SARS-CoV, Tyrosinase

Cat.No: T1508

Synonym: Dacogen,NSC 127716,地西他滨,Deoxycytidine,5-Aza-2'-deoxycytidine

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA Methyltransferase

Cat.No: T2218

Synonym: Azaguanine-8,SK 1150,8-氮鸟嘌呤,NSC-749,SF-337

Target: Nucleoside Antimetabolite/Analog, Others, Endogenous Metabolite

Cat.No: T1339

Synonym: 阿托胞苷,Azacitidine,NSC 102816,Mylosar,Ladakamycin,5-氮杂胞苷,5-AzaC

Target: Nucleoside Antimetabolite/Analog, DNA Methyltransferase, Antibacterial, Antibiotic, Autophagy

Orotic acid zinc

Cat.No: T3271

Synonym: 乳清酸锌二水合物,Orotic acid zinc salt dihydrate,Zinc Orotate

Target: Nucleoside Antimetabolite/Analog, Others, Endogenous Metabolite

Cat.No: T1272

Synonym: 阿糖胞苷,Ara-C,Cytosine Arabinoside,Cytosine β-D-arabinofuranoside,Arabinocytidine

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Endogenous Metabolite, Autophagy, HSV

Cat.No: T1506

Synonym: Adenine Arabinoside,阿糖腺苷,9-β-D-Arabinofuranosyladenine,Vira-A,Arabinosyladenine,Ara-A

Target: Nucleoside Antimetabolite/Analog, Tyrosine Kinases, DNA/RNA Synthesis, Antibiotic, HSV

5'-Methylthioadenosine

Cat.No: T8227

Synonym: Methylthioadenosine,5-脱氧-5-甲硫腺苷,5'-(Methylthio)-5'-deoxyadenosine,5'-Deoxy-5'-(methylthio)adenosine,5'-S-Methyl-5'-thioadenosine

Target: Endogenous Metabolite

N4-Acetylcytidine

Cat.No: T4456

Synonym: N4-乙酰胞苷,N-Acetylcytidine

Target: Others, Endogenous Metabolite

N2-methylguanine

Cat.No: T13791

Synonym: 6-羟基-2-氨甲基嘌呤

Target: DNA/RNA Synthesis, Endogenous Metabolite, Antibacterial

3’-O-Methyl guanosine

Cat.No: TNU0157

Target: Endogenous Metabolite

2'-Deoxyadenosine

Cat.No: T20041

Synonym: 2'-脱氧腺苷,NSC-141848,NSC141848,NSC 141848

Target: Endogenous Metabolite

3-Methyluridine

Cat.No: T13499

Target: Endogenous Metabolite

Cat.No: T38251

Target: Nucleoside Antimetabolite/Analog, Antibiotic

2'-Deoxycytidine-5'-diphosphate trisodium

Cat.No: T4972

Synonym: dCDP,2'-脱氧胞苷-5'-二磷酸三钠盐

Target: Endogenous Metabolite

2'-Deoxyguanosine monohydrate

Cat.No: T4715

Synonym: 2'-脱氧鸟苷一水合物,Guanine-2'-deoxyriboside

Target: Others, Endogenous Metabolite

N4-Benzoyl-2′-deoxycytidine

Cat.No: T7961

Synonym: N-苯甲酰-2'-脱氧胞苷

Target: Others

2'-Deoxyguanosine

Cat.No: T22218

Synonym: Deoxyguanosine,Guanine deoxyriboside

Target: Endogenous Metabolite

Cat.No: TMO2681

Synonym: 9-Beta-D-Ribofuranosylxanthine,黄嘌呤核苷,Xanthine riboside

Target: Others, Endogenous Metabolite

2'-Deoxyinosine

Cat.No: T1709

Synonym: Guanine deoxyriboside,Deoxyinosine,2'-脱氧肌苷

Target: Others, Endogenous Metabolite

N2,N2-Dimethylguanosine

Cat.No: TQ0193

Synonym: N2,N2-二甲基鸟苷

Target: Endogenous Metabolite

5-Methyl-2'-deoxycytidine

Cat.No: T7457

Synonym: 5-Methyldeoxycytidine,5-甲基-2'-脱氧胞苷,5MedCyd

Target: DNA Methyltransferase, Endogenous Metabolite

2'-Deoxyadenosine monohydrate

Cat.No: T2752

Target: Others, Endogenous Metabolite

Cat.No: T6523

Synonym: 鸟苷,DL-Guanosine,Vernine,Guanozin

Target: Endogenous Metabolite, HSV

1-Methylguanosine

Cat.No: T7548

Synonym: 1-甲基鸟苷,N1-Methylguanosine,1-甲基鸟酐

Target: Endogenous Metabolite

Cat.No: T2993

Synonym: 3'-Deoxyadenosine,虫草素

Target: MMP, TNF, Antibacterial, Antibiotic, Autophagy

5-Methyluridine

Cat.No: T5282

Synonym: Ribothymidine,5-甲基尿甙,Thymine riboside

Target: Others, Endogenous Metabolite

Cat.No: T7004

Synonym: 结核菌素,杀结核菌素,Sparsomycin A,7-Deazaadenosine

Target: Influenza Virus, DNA/RNA Synthesis, Antibacterial, Antibiotic

Allopurinol riboside

Cat.No: T13539

Target: Others, Endogenous Metabolite, Parasite, Drug Metabolite

ATP disodium salt hydrate

Cat.No: T2812

Synonym: ATP disodium,ATP disodium salt,Adenosine disodium triphosphate,三磷酸腺苷二钠盐

Target: Others, Endogenous Metabolite

Blasticidin S HCl

Cat.No: T64911

Target: Antibiotic

Nicotinamide riboside chloride

Cat.No: T6220

Synonym: 烟酰胺核糖氯酸盐,烟酰胺核苷

Target: Sirtuin, Endogenous Metabolite

Cat.No: TNU0052

Synonym: 9-(beta-D-Ribofuranosyl)-9H-purine

Target: Apoptosis

Inosine-5'-triphosphate trisodium salt

Cat.No: T4897

Synonym: ITP,肌苷-5'-三磷酸三钠盐,三磷酸肌苷三钠盐,Inosine 5'-triphosphate trisodium salt

Target: Others, Endogenous Metabolite

Adenosine 5'-monophosphate monohydrate

Cat.No: T0853L

Synonym: 5'-AMP,腺苷-5'-单磷酸一水合物,5'-AMP monohydrate,5'-Adenylic acid

Target: AMPK, Adenosine Receptor, HSV

Uridine 5'-monophosphate

Cat.No: T4718

Synonym: Uridylic acid,尿苷5-单磷酸,UMP,Uridine phosphate,Uridine 5'-phosphoric acid,5'-Uridylic acid

Target: Others, Endogenous Metabolite

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02279	Nucleoside phosphorylase/PNP Protein, Human, Recombinant (His) PUNP,PRO1837,purine nucleoside phosphorylase,NP	Human	E. coli
	Purine nucleoside phosphorylase (PNP) is a purine-metabolizing enzyme that catalyzes the reversible phosphorolysis of 6-oxypurine (deoxy)nucleosides to their respective bases and (deoxy)ribose-1-phosphate. It is a key enzyme in the purine salvage pathway of mammalian cells. Purine nucleoside phosphorylase is a transferase that catalyzes the addition of phosphate and removal of a purine base from guanosine and similar nucleosides.PNP defects result in metabolic abnormalities and fatal T cell immu...
TMPH-00099	NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) Nucleoside diphosphate kinase 1,NDK1,Nucleoside...	Arabidopsis thaliana	P. pastoris (Yeast)
	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Plays a role in response to reactive oxygen species (ROS) stress. NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in yeast with N-10xHis and C-Myc tag. The predicted molecular weight is 20.5 kDa and the accession number is P39207.
TMPH-01802	NME4 Protein, Human, Recombinant (GST) Nucleoside diphosphate kinase D,Nucleoside...	Human	E. coli
	NME4 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 44.3 kDa and the accession number is O00746.
TMPH-03452	NDPK Protein, S. cerevisiae, Recombinant (His) Nucleoside diphosphate kinase,YNK1	Saccharomyces cerevisiae	P. pastoris (Yeast)
	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Required for repair of UV radiation- and etoposide-induced DNA damage. NDPK Protein, S. cerevisiae, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 19.2 kDa and the accession number is P36010.
TMPH-03451	NDPK Protein, S. cerevisiae, Recombinant (E. coli, His) YNK1,Nucleoside diphosphate kinase	Saccharomyces cerevisiae	E. coli
	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Required for repair of UV radiation- and etoposide-induced DNA damage. NDPK Protein, S. cerevisiae, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.2 kDa and the accession number is P36010.
TMPH-00477	NDK, cytosolic Protein, Dictyostelium discoideum, Recombinant (His & V5) ndkC-1,ndkC-2,Nucleoside diphosphate kinase, cytoso...	Dictyostelium discoideum	E. coli
	NDK, cytosolic Protein, Dictyostelium discoideum, Recombinant (His & V5) is expressed in E. coli.
TMPJ-01308	ITPase Protein, Human, Recombinant (His) Nucleoside-Triphosphate Diphosphatase,Nucleosid...	Human	E. coli
	Inosine Triphosphate Pyrophosphatase (ITPase) is a cytoplasmic enzyme that belongs to the HAM1 NTPase family. ITPase hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP) and deoxyinosine triphosphate (dITP) to the monophosphate nucleotide (IMP) and diphosphate. The ITPase enzyme acts as a homodimer and does not distinguish between the deoxy- and ribose forms. ITPase probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation...
TMPY-00116	MTH1 Protein, Human, Recombinant (His) MTH1,nudix (nucleoside diphosphate linked moiety X)...	Human	E. coli
	NUDT1 (Nudix Hydrolase 1) is a Protein Coding gene. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates to monophosphates, thereby preventing misincorporation. The NUDT1 protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Cancers can survive the oxidative conditions by upregulating nucleoside diphosphate lin...
TMPY-02278	NUDT2 Protein, Human, Recombinant (His) APAH1,nudix (nucleoside diphosphate linked moiety X...	Human	E. coli
	NUDT2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 18.3 kDa and the accession number is P50583.
TMPH-02964	UMP-CMP kinase/CMPK1 Protein, Mouse, Recombinant (His & SUMO) Cmpk1,UMP-CMP kinase,Nucleoside-diphosphate kinase,...	Mouse	E. coli
	Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity. UMP-CMP kinase/CMPK1 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 38.2 kDa and the accession number is Q9DBP5.
TMPY-03849	NUDT5 Protein, Human, Recombinant (His) hYSAH1,YSAH1,nudix (nucleoside diphosphate linked m...	Human	E. coli
	NUDT5 (Nudix Hydrolase 5) is a Protein Coding gene. This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates. ADP-sugar Pyrophosphatase, also known as NUDT5, eliminates toxic nucleotide derivatives from the cell and regulates the levels of important signaling nucleotides and their metabolites. It is widely expressed in the liver, skin, and other tissues. NUDT5 functions as a MutT...
TMPY-04467	NME1 Protein, Human, Recombinant (His) NME/NM23 nucleoside diphosphate kinase 1,NB,NDPK-A,...	Human	E. coli
	NME1, also known as Nucleoside Diphosphate Kinase A (NDK-A), or NM23-H1, belongs to the NDK family. NM23-H1 is known to have a metastasis suppressive activity in many tumor cells. Recent studies have shown that the interacting proteins with NM23-H1 which mediate cell proliferation, may act as modulators of the metastasis suppressor activity. The interacting proteins with NM23-H1 can be classified into 3 groups. The first group of proteins can be classified as upstream kinases of NM23-H1 such as ...
TMPH-01801	NME2 Protein, Human, Recombinant (His & Myc) NME2,nm23-H2,Histidine protein kinase NDKB,Nucleoside	Human	E. coli
	NME2 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 24.2 kDa and the accession number is P22392.
TMPH-01631	DCP2 Protein, Human, Recombinant (His) m7GpppN-mRNA hydrolase,mRNA-decapping enzyme 2,Nucleosid...	Human	E. coli
	DCP2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 48.4 kDa and the accession number is Q8IU60.
TMPH-03283	CD39 Protein, Rat, Recombinant (His) ATP diphosphohydrolase,Entpd1,Nucleoside triphospha...	Rat	Baculovirus Insect Cells
	In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well.
TMPH-03284	CD39 Protein, Rat, Recombinant (E. coli, His) Entpd1,ATP-DPH,Ecto-ATP diphosphohydrolase 1,CD39,Ecto-ATPas...	Rat	E. coli
	In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well.
TMPY-02929	ENTPD2 Protein, Human, Recombinant (aa 29-460, His) ectonucleoside triphosphate diphosphohydrolase 2,NT...	Human	Baculovirus Insect Cells
	NTPDase 2, also known as ENTPD2, belongs to the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). Members of E-NTPDase family are nucleotidases able to hydrolyze 5′-nucleoside tri- and/or diphosphates; the main role of these enzymes is the termination of purinergic signaling. NTPDases are ubiquitous and were previously shown in other parasites including the trypanosomatides of genus Leishmania and in T. brucei. NTPase activity would act as a timer and is crucial to T. gondii in...
TMPH-00156	Ribonuclease Protein, Bacillus amyloliquefaciens, Recombinant (His) Barnase,Ribonuclease,RNase Ba	Bacillus amyloliquefaciens	E. coli
	Hydrolyzes phosphodiester bonds in RNA, poly- and oligoribonucleotides resulting in 3'-nucleoside monophosphates via 2',3'-cyclophosphate intermediates. Ribonuclease Protein, Bacillus amyloliquefaciens, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 13.3 kDa and the accession number is P00648.
TMPK-00852	ENPP1 Protein, Human, Recombinant (His & Avi), Biotinylated E-NPP 1,NPPase,PC1,NPP1,PCA1,ENPP1,Ly-41 Antigen,PCA1ARHR2,M...	Human	HEK293 Cells
	Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (ePPi). Mechanical stimulation regulates ENPP-1 expression. ENPP1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 98.29 kDa and the accession number is P22413.
TMPK-00854	ENPP1 Protein, Human, Recombinant (C-His) M6S1,E-NPP 1,PCA1,PDNP1,ENPP1,NPPase,NPPS,M6S1NPP1,PCA1ARHR2...	Human	HEK293 Cells
	Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (ePPi). Mechanical stimulation regulates ENPP-1 expression. ENPP1 Protein, Human, Recombinant (C-His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 96.5 kDa and the accession number is P22413.
TMPH-01211	DGUOK Protein, Human, Recombinant (His & SUMO) Deoxyguanosine kinase, mitochondrial,Deoxyadenosine kinase, ...	Human	E. coli
	Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine. In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on DGUOK and TK2. Phosphorylates certain nucleoside analogs. Widely used as target of antiviral and chemotherapeutic agents.
TMPK-00853	ENPP1 Protein, Human, Recombinant (N-His) PDNP1,NPP1,NPPase,PCA1ARHR2,PCA1,M6S1,Ly-41 Antigen,ENPP1,E-...	Human	HEK293 Cells
	Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (ePPi). Mechanical stimulation regulates ENPP-1 expression. ENPP1 Protein, Human, Recombinant (N-His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 96.5 kDa and the accession number is P22413.
TMPK-00781	ENPP1 Protein, Mouse, Recombinant (His) ENPP1,PC1,PCA1ARHR2,PCA1,NPP1,M6S1NPP1,PDNP1,NPPS,Ly-41 Anti...	Mouse	HEK293 Cells
	Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (ePPi). Mechanical stimulation regulates ENPP-1 expression. ENPP1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 95.99 kDa and the accession number is P06802-1.
TMPY-03617	GMPR Protein, Human, Recombinant (His) GMPR1,guanosine monophosphate reductase	Human	E. coli
	GMPR, also known as GMPR1, belongs to the IMPDH/GMPR family.This familyofenzymesincludesIMP dehydrogenaseandGMP reductase. These enzymes are involved inpurine metabolism and adopt aTIM barrelstructure. GMPR is an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. GMPR functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
TMPJ-01406	MOB4 Protein, Human, Recombinant (His) PREI3,MOBKL3,Mps One Binder Kinase Activator-Like 3,Mob1 Hom...	Human	E. coli
	MOB-Like Protein Phocein is a member of the MOB1/Phocein Family. MOB-Like Protein Phocein is associated with membranes and the Golgi stacks. It is present in the cytosol, where it behaves as a protein complex. It has been shown that MOB-Like Protein Phocein interacts with DNM1, EPS15 and Nucleoside Diphosphate Kinase. MOB-Like Protein Phocein is the major partner of Striatin Family members and may play a important role in membrane trafficking, specifically in membrane budding reactions.
TMPY-04480	UMP-CMP kinase/CMPK1 Protein, Human, Recombinant (His) CMPK,UMPK,UMK,CK,UMP-CMPK,CMK,cytidine monophosphate (UMP-CM...	Human	Baculovirus Insect Cells
	CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), resulting in the formation of ADP and the corresponding nucleoside diphosphate. CMPK1 also has a significant role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. In the meanwhile, CMPK1 functions in cellular nucleic acid bi...
TMPJ-00922	DCK Protein, Human, Recombinant (His & T7) DCK,Deoxycytidine Kinase	Human	E. coli
	Deoxycytidine Kinase (DCK) is a member of the DCK/DGK family. DCK exists as a homodimer and is localized to the nucleus. DCK is required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG), and deoxyadenosine (dA). DCK has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. In addition, DCK is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and c...
TMPY-03330	BPHL Protein, Human, Recombinant (His) biphenyl hydrolase-like (serine hydrolase),VACVASE,MCNAA,BPH...	Human	E. coli
	BPHL is a member of the serine protease family. BPHL is expressed large quantities in liver and kidney and in minor quantities in heart, intestine and skeletal muscle. BPHL is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol. It catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir ...
TMPJ-00496	PGM2 Protein, Human, Recombinant (His) Phosphopentomutase,Phosphodeoxyribomutase,Glucose phosphomut...	Human	E. coli
	Phosphoglucomutase-2 (PGM2) is a member of PGM family, which catalyzes the inter-conversion of sugar phosphates and participates in anabolic and catabolic reactions. When cells are grown in glucose, PGM catalyzes the conversion of glucose-6-phosphate to glucose-1-phosphate an important precursor required for the synthesis of UDP glucose and trehalose. PGM2 catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphope...
TMPY-03508	XTP3TPA Protein, Human, Recombinant (His) XTP3TPA,dCTP pyrophosphatase 1,RS21C6,CDA03	Human	E. coli
	DCTPP1 hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. It has a strong preference for modified dCTP. DCTPP1’s activity is highest with 5-iodo-dCTP, followed by 5-bromo-dCTP, unmodified dCTP, 5-methyl-dCTP and 5-chloro-dCTP. DCTPP1 also hydrolyzes 2-chloro-dATP and 2-hydroxy-dATP with lower efficiency, and has even lower activity with unmodified dATP, dTTP and dUTP (in vitro). DCTPP1 does not hydrolyze ATP, UTP, ITP, GTP, dADP, dCDP or dGTP....
TMPY-02893	NT5C3A/NT5C3 Protein, Human, Recombinant P5N1,P5N-1,hUMP1,NT5C3,cN-III,PSN1,UMPH1,UMPH,POMP,5'-nucleo...	Human	E. coli
	NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. NT5C3A expression required both an intronic IFN-stimulated response element and the IFN-stimulated transcription factor IRF1. Overexpression of NT5C3A, but...
TMPJ-00682	CD39L1 Protein, Mouse, Recombinant (His) Ectonucleoside triphosphate diphosphohydrolase 2,En...	Mouse	HEK293 Cells
	CD39L1 protein (ENTPD2 or NTPDase2) is a member of the ecto-nucleoside triphosphate diphosphohydrolase family which the main role is termination of purinergic signaling. CD39L1 gene encodes a precursor protein with 495 amino acid residues which generates a 437 amino acid residues mature protein after processing. It is an ecto-nucleotidase that found on the surface of vascular adventitial cells and accessory vascular cells. CD39L1 is a Ca2+- and Mg2+-dependent enzyme that activates platelets by p...

重组蛋白

Nucleoside phosphorylase/PNP Protein, Human, Recombinant (His)

Cat.No: TMPY-02279

Species: Human

Expression System: E. coli

NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc)

Cat.No: TMPH-00099

Species: Arabidopsis thaliana

Expression System: P. pastoris (Yeast)

NME4 Protein, Human, Recombinant (GST)

Cat.No: TMPH-01802

Species: Human

Expression System: E. coli

NDPK Protein, S. cerevisiae, Recombinant (His)

Cat.No: TMPH-03452

Species: Saccharomyces cerevisiae

Expression System: P. pastoris (Yeast)

NDPK Protein, S. cerevisiae, Recombinant (E. coli, His)

Cat.No: TMPH-03451

Species: Saccharomyces cerevisiae

Expression System: E. coli

NDK, cytosolic Protein, Dictyostelium discoideum, Recombinant (His & V5)

Cat.No: TMPH-00477

Species: Dictyostelium discoideum

Expression System: E. coli

ITPase Protein, Human, Recombinant (His)

Cat.No: TMPJ-01308

Species: Human

Expression System: E. coli

MTH1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00116

Species: Human

Expression System: E. coli

NUDT2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02278

Species: Human

Expression System: E. coli

UMP-CMP kinase/CMPK1 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02964

Species: Mouse

Expression System: E. coli

NUDT5 Protein, Human, Recombinant (His)

Cat.No: TMPY-03849

Species: Human

Expression System: E. coli

NME1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04467

Species: Human

Expression System: E. coli

NME2 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01801

Species: Human

Expression System: E. coli

DCP2 Protein, Human, Recombinant (His)

Cat.No: TMPH-01631

Species: Human

Expression System: E. coli

CD39 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03283

Species: Rat

Expression System: Baculovirus Insect Cells

CD39 Protein, Rat, Recombinant (E. coli, His)

Cat.No: TMPH-03284

Species: Rat

Expression System: E. coli

ENTPD2 Protein, Human, Recombinant (aa 29-460, His)

Cat.No: TMPY-02929

Species: Human

Expression System: Baculovirus Insect Cells

Ribonuclease Protein, Bacillus amyloliquefaciens, Recombinant (His)

Cat.No: TMPH-00156

Species: Bacillus amyloliquefaciens

Expression System: E. coli

ENPP1 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00852

Species: Human

Expression System: HEK293 Cells

ENPP1 Protein, Human, Recombinant (C-His)

Cat.No: TMPK-00854

Species: Human

Expression System: HEK293 Cells

DGUOK Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01211

Species: Human

Expression System: E. coli

ENPP1 Protein, Human, Recombinant (N-His)

Cat.No: TMPK-00853

Species: Human

Expression System: HEK293 Cells

ENPP1 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00781

Species: Mouse

Expression System: HEK293 Cells

GMPR Protein, Human, Recombinant (His)

Cat.No: TMPY-03617

Species: Human

Expression System: E. coli

MOB4 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01406

Species: Human

Expression System: E. coli

UMP-CMP kinase/CMPK1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04480

Species: Human

Expression System: Baculovirus Insect Cells

DCK Protein, Human, Recombinant (His & T7)

Cat.No: TMPJ-00922

Species: Human

Expression System: E. coli

BPHL Protein, Human, Recombinant (His)

Cat.No: TMPY-03330

Species: Human

Expression System: E. coli

PGM2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00496

Species: Human

Expression System: E. coli

XTP3TPA Protein, Human, Recombinant (His)

Cat.No: TMPY-03508

Species: Human

Expression System: E. coli

NT5C3A/NT5C3 Protein, Human, Recombinant

Cat.No: TMPY-02893

Species: Human

Expression System: E. coli

CD39L1 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00682

Species: Mouse

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
T60016	VV116 GS-621763-d1,JT001	SARS-CoV; RSV	Microbiology/Virology
	VV116 (JT001) 是一种针对呼吸道合胞病毒和 SARS-CoV-2 感染的选择性和口服活性核苷抗病毒剂。
TMIH-0555	Telbivudine-d3
	Telbivudine-d3 是 Telbivudine 的氘代化合物。Telbivudine 的 CAS 号为 3424-98-4。Telbivudine 是一种乙型肝炎病毒复制的抗病毒抑制剂，是一种具有口服活性的胸腺嘧啶核苷类似物。
T12702	Remdesivir-D5 GS-5734-D5	Others	Others
	Remdesivir-D5 is a deuterium labeled Remdesivir. Remdesivir is a nucleoside analogue, with effective antiviral activity.
T11247	Etravirine D4 R-165335 D4,TMC-125 D4,依曲韦林 D4	Others	Others
	Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV. Etravirine D4 is the deuterium labeled Etravirine.
T11814	Lamivudine 13C,15N2	Others	Others
	Lamivudine 13C,15N2, an impurity of Lamivudine (BCH-189), functions as an inhibitor of both HIV-1/2 reverse transcriptase and hepatitis B virus reverse transcriptase, classifying it as a nucleoside reverse transcriptase inhibitor (NRTIs).
TMID-0266	Stavudine-α,α,α,6-d4
	Stavudine-α,α,α,6-d4 是 Stavudine 的氘代化合物。Stavudine 的 CAS 号为 3056-17-5。Stavudine 是一种口服活性核苷逆转录酶抑制剂，还抑制线粒体 DNA 的复制，具有抗HIV-1和HIV-2的活性。它降低 NLRP3 炎症小体激活，调节淀粉样 β 自噬，诱导细胞凋亡。
TMIJ-0217	Abacavir-d4
	Abacavir-d4 是 Abacavir 的氘代化合物。Abacavir 的 CAS 号为 136470-78-5。Abacavir是一种核苷类似物逆转录酶抑制剂。
TMIJ-0254	Remdesivir-d4
	Remdesivir-d4 是 Remdesivir 的氘代化合物。Remdesivir 的 CAS 号为 1809249-37-3。Remdesivir是一种核苷类似物，具有抗病毒活性，在 HAE 细胞中，对SARS-CoV和MERS-CoV的EC50值为 74 nM，有潜力用于 2019-nCoV (COVID-19) 研究。
TMID-0206	Nevirapine-d3
	Nevirapine-d3 是 Nevirapine 的氘代化合物。Nevirapine 的 CAS 号为 129618-40-2。Nevirapine 是一种HIV-1逆转录酶非核苷抑制剂，Ki值为 270 μM，可用于研究 HIV/AIDS。
TMIJ-0013	Acyclovir-d4
	Acyclovir-d4 是 Acyclovir 的氘代化合物。Acyclovir 的 CAS 号为 59277-89-3。Acyclovir是鸟嘌呤类似物和具有口服活性的抗病毒剂。它对HSV-1(IC50为 0.85 μM)，HSV-2(IC50为 0.86 μM) 和水痘带状疱疹病毒有活性。
TMID-0205	Nevirapine-d4
	Nevirapine-d4 是 Nevirapine 的氘代化合物。Nevirapine 的 CAS 号为 129618-40-2。Nevirapine 是一种HIV-1逆转录酶非核苷抑制剂，Ki值为 270 μM，可用于研究 HIV/AIDS。
T38297	Ribavirin-13C5 Ribavirin-13C5
	Ribavirin-13C5is intended for use as an internal standard for the quantification of ribavirin by GC- or LC-MS. Ribavirin is an antiviral guanosine nucleoside analog.1,2Upon entry into cells, ribavirin is metabolized to an active triphosphate form that induces viral RNA chain termination and inhibits viral polymerases. It reduces replication in a panel of seven RNA and four DNA viruses in Vero cells (EC50s = 2-95 μg/ml).3Ribavirin also reduces replication of severe acute respiratory syndrome coro...

同位素标记化合物

Cat.No: T60016

Synonym: GS-621763-d1,JT001

Target: SARS-CoV, RSV

Cat.No: TMIH-0555

Cat.No: T12702

Synonym: GS-5734-D5

Target: Others

Cat.No: T11247

Synonym: R-165335 D4,TMC-125 D4,依曲韦林 D4

Target: Others

Lamivudine 13C,15N2

Cat.No: T11814

Target: Others

Stavudine-α,α,α,6-d4

Cat.No: TMID-0266

Cat.No: TMIJ-0217

Cat.No: TMIJ-0254

Cat.No: TMID-0206

Cat.No: TMIJ-0013

Cat.No: TMID-0205

Cat.No: T38297

Synonym: Ribavirin-13C5

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