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Search Results for " histone methyltransferase "

Targets Recommended: Histone Methyltransferase Histone Methyltransferase Antifolate Histamine Receptor

114

抑制剂 & 化合物

2

天然产物

12

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T8548	Metoprine	Histone Methyltransferase; Antifolate; Histamine Receptor	Cell Cycle/Checkpoint; Chromatin/Epigenetic; GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Metoprine 是一种有效的组胺 N-甲基转移酶抑制剂，具有抗肿瘤活性。它是一种二氨基嘧啶衍生物，可以透过血脑屏障，并通过抑制 HMT 增加脑组胺水平。
T8381	Amodiaquine	Others; Histone Methyltransferase; Parasite	Chromatin/Epigenetic; Microbiology/Virology; Others
	Amodiaquine 是一种合成的4-氨基喹啉类抗疟剂，是一种有口服活性的组胺 N-甲基转移酶抑制剂。它也是一种Nurr1激动剂，有抗炎活性，可特异性结合Nurr1的配体结合域，EC50约为20 μM。
T2097	C-7280948 C7280948	Histone Methyltransferase	Chromatin/Epigenetic
	C-7280948 是一种选择性有效的PRMT1抑制剂，IC50值 12.75 μM。
T5322	BCI-121	Histone Methyltransferase	Chromatin/Epigenetic
	BCI-121是一种底物竞争性 SMYD3 抑制剂，可抑制癌细胞的增殖。
T3084	SGC707	Histone Methyltransferase	Chromatin/Epigenetic
	SGC707 是 PRMT3化学探针，是一种有效的、选择性的、细胞活性的 PRMT3 变构抑制剂，IC50值为 31 nM。
T1775	GSK503	Histone Methyltransferase	Chromatin/Epigenetic
	GSK503是一种高效特异性EZH2甲基转移酶抑制剂，Ki 值为3到27 nM，具有潜在的抗肿瘤活性。
T4021	UNC3866	Histone Methyltransferase	Chromatin/Epigenetic
	UNC3866 CBX7-H3 相互作用的有效拮抗剂，IC50为 66±1.2 nM。
T1905	EPZ005687	Histone Methyltransferase	Chromatin/Epigenetic
	EPZ005687 是一种选择性EZH2抑制剂，Ki 值为 24 nM，对其选择性是对 EZH1 的 50 倍，对其他 15 种甲基转移酶的 500 倍。
T9584	UNC6934	Others; Histone Methyltransferase	Chromatin/Epigenetic; Others
	UNC6934 是一种针对 NSD2 的 N 端 PWWP (PWWP1) 结构域的化学探针，可定位核仁。
T2435	EPZ011989	Histone Methyltransferase	Chromatin/Epigenetic
	EPZ011989是一种高选择性可口服的 EZH2抑制剂，对wt EZH2以及EZH2突变型Ki 值<3nM。
T15624	JNJ-64619178	Histone Methyltransferase	Chromatin/Epigenetic
	JNJ-64619178 是一种选择性的、口服活性的、假不可逆的蛋白质精氨酸甲基转移酶 5 抑制剂，IC50为 0.14 nM，有用于肺癌的研究潜力。
TQ0100	AZ505	Histone Methyltransferase	Chromatin/Epigenetic
	AZ505 是一种选择性SMYD2抑制剂，IC50值为 0.12 μM。
T15194	EBI-2511	Histone Methyltransferase	Chromatin/Epigenetic
	EBI-2511 是一种高效且具有口服活性的 EZH2 抑制剂，在 Pfeffiera 细胞系中的 IC50值为 6 nM。
T7403	BAY-598	Histone Methyltransferase	Chromatin/Epigenetic
	BAY-598 是SMYD2的选择性抑制剂，IC50值为 27 nM。
T13780	MS1943	Apoptosis; Histone Methyltransferase	Apoptosis; Chromatin/Epigenetic
	MS1943 是一种具有口服生物活性的 EZH2选择性降解剂，IC50为 120 nM。它显著降低了许多三阴性乳腺癌和其他癌及非癌细胞系中的 EZH2蛋白水平，能有效阻止多个三阴性乳腺癌和其他癌细胞系的增殖。
T15201	MAK683	Histone Methyltransferase	Chromatin/Epigenetic
	MAK683 是胚胎外胚层发育 (EED) 抑制剂。在 EED Alphascreen 结合、LC-MS 和 ELISA 测定中，IC50值为 59、89 和 26 nM。
T6900	MS023	Histone Methyltransferase	Chromatin/Epigenetic
	MS023 是一种有效的、选择性的、细胞活性的 I 型 PRMT 抑制剂，对 PRMT1、PRMT3、PRMT4、PRMT6和 PRMT8的 IC50分别为 30、119、83、4 和 5 nM。
T7089	SGC2085	Histone Methyltransferase	Chromatin/Epigenetic
	SGC2085是一种高效选择性CARM1抑制剂，IC50值为50 nM。
T10205	A-395	Histone Methyltransferase	Chromatin/Epigenetic
	A-395 是一种多梳抑制复合物 2 (PRC2) 蛋白质-蛋白质相互作用的拮抗剂，可有效抑制三聚体 PRC2 复合物 (EZH2-EED-SUZ12)，IC50为 18 nM。
T3057	UNC1999	Histone Methyltransferase; Autophagy	Autophagy; Chromatin/Epigenetic
	UNC1999 是一种可口服的，选择性和 SAM-竞争性的 EZH2和 EZH1抑制剂，IC50分别为 <10 nM 和 45 nM。
T1841	UNC0379	Histone Methyltransferase	Chromatin/Epigenetic
	UNC0379 是一种选择性的、底物竞争性的赖氨酸甲基转移酶 SETD8 抑制剂，IC50值为 7.3 μM，也选择性抑制其他 15 种甲基转移酶。
T4343	A-196 A 196	Histone Methyltransferase	Chromatin/Epigenetic
	A-196 是一种选择性有效的 SUV420H1和 SUV420H2抑制剂，IC50值分别为 0.025 和 0.144 μM。它是一种 SUV4-20的化学探针，以底物竞争性方式抑制 SUV4-20，用于研究组蛋白甲基转移酶在基因组完整性中的作用。
T3081	EPZ004777	Apoptosis; Histone Methyltransferase	Apoptosis; Chromatin/Epigenetic
	EPZ004777 是一种选择性 DOT1L 抑制剂，IC50为 0.4 nM。
T6879	LLY-507 LLY507,LLY 507	Histone Methyltransferase	Chromatin/Epigenetic
	LLY-507 是一种有效的、细胞活性的、特异性的蛋白质赖氨酸甲基转移酶 SMYD2 抑制剂。它是一种化学探针，用于解析 SMYD2 在癌症和其他生物过程中的功能。它有抑制 SMYD2 甲基化 p53 肽的能力，IC50小于 15 nM。
T6059	GSK343	Histone Methyltransferase; Autophagy	Autophagy; Chromatin/Epigenetic
	GSK343 是一种特异性且有效的 EZH2 抑制剂，IC50为 4 nM。它对 EZH1 的特异性活性是 60 倍。
T36631	BAY-6035	MEK; Histone Methyltransferase	Chromatin/Epigenetic; MAPK
	BAY-6035 是 SET 和 MYND 结构域蛋白 3 (SMYD3) 的抑制剂。 BAY-6035 的选择性比其他组蛋白甲基转移酶高 100 倍以上。
T3099	Pinometostat EPZ-5676	Histone Methyltransferase	Chromatin/Epigenetic
	Pinometostat (EPZ-5676) 是有效的DOT1L 组蛋白甲基转移酶抑制剂，Ki 为 80 pM。它可用于研究多种白血病治疗的实验。
T3257	UNC0638	Influenza Virus; Histone Methyltransferase; Autophagy	Autophagy; Chromatin/Epigenetic; Microbiology/Virology
	UNC0638 是 β-蛋白赖氨酸甲基转移酶 G9a 和 GLP 的抑制剂，选择性抑制表观遗传和非表观遗传靶标。
T3458	EED226	Histone Methyltransferase	Chromatin/Epigenetic
	EED226 是多梳抑制复合物 2 抑制剂，是一种有效的、选择性的、可口服的胚胎外胚层发育 (EED) 抑制剂，IC50 为 22 nM，具有强抗肿瘤活性。当 H3K27me0 肽用作体外酶法测定的底物时，它抑制 PRC2的 IC50为 23.4 nM。
T14841	BVT948	Phosphatase; P450; Histone Methyltransferase	Chromatin/Epigenetic; Metabolism
	BVT948 是一种蛋白酪氨酸磷酸酶抑制剂，还可以抑制赖氨酸甲基转移酶 SETD8 (KMT5A) 和几种细胞色素 P450 (P450) 同工型。
T4166	UNC0642 UNC-0642,UNC 0642	Histone Methyltransferase	Chromatin/Epigenetic
	UNC0642是有效选择性赖氨酸甲基转移酶G9a 和GLP 抑制剂，抑制G9a 的IC50值小于2.5 nM。
T40254	MRTX-1719	Histone Methyltransferase	Chromatin/Epigenetic
	MRTX-1719 是有效的PRMT5/MTA 复合体选择性抑制剂，其对PRMT5/MTAMTAPDELSDMA 细胞系的IC50值为 <10 nM。
T13954	UNC6852	Histone Methyltransferase; Ligands for Target Protein for PROTAC; PROTACs	Chromatin/Epigenetic; PROTAC
	UNC6852 包含一个 EED 配体 (IC50 = 247 nM) 和一个 von Hippel-Lindau 配体，是一种基于 PROTAC 的特异性多梳抑制复合物 2 (PRC2) 降解剂。
T7378	BRD9539	Histone Methyltransferase	Chromatin/Epigenetic
	BRD9539 是一种组蛋白甲基转移酶G9a 抑制剂，IC50为 6.3 μM，还抑制PRC2活性。
T27133	DCLX069 DCLX 069,DCLX-069	Histone Methyltransferase	Chromatin/Epigenetic
	DCLX069 是一种选择性蛋白精氨酸甲基转移酶 1 抑制剂，IC50值为 17.9 µM，对 PRMT4 和 PRMT6 的活性较低。它可有效阻断乳腺癌、肝癌和急性髓性白血病细胞系中的细胞增殖。
T7305	JQEZ5	Histone Methyltransferase	Chromatin/Epigenetic
	JQEZ5 是一种选择性EZH2赖氨酸甲基转移酶抑制剂，具有抗肿瘤作用。它以 SAM 竞争性方式抑制PRC2的酶功能，IC50为 80 nM。
T2379	UNC1215	Apoptosis; Epigenetic Reader Domain; Histone Methyltransferase	Apoptosis; Chromatin/Epigenetic
	UNC1215 是一种选择性 L3MBTL3甲基赖氨酸结构域的拮抗剂，IC50为40 nM，Kd 为 120 nM。它可研究恶性脑瘤。
T7194	CM-272	Apoptosis; DNA Methyltransferase; Histone Methyltransferase	Apoptosis; Chromatin/Epigenetic
	CM-272 是一种可逆底物竞争性双重G9a/DNA 甲基转移酶选择性抑制剂，具有抗肿瘤活性。它抑制细胞增殖并促进细胞凋亡，诱导干扰素刺激的基因和免疫原性细胞死亡。它抑制G9a、DNMT1、DNMT3A、DNMT3B 和GLP，IC50分别为 8 nM、382 nM、85 nM、1200 nM 和 2 nM。
T12428L	PF-06726304	Histone Methyltransferase	Chromatin/Epigenetic
	PF-06726304 是选择性EZH2有效抑制剂，具有强抗肿瘤生长活性。它抑制野生型和 Y641N 突变型 EZH2，Ki 分别为 0.7 和 3.0 nM。
T28996	TP-064 TP 064	Histone Methyltransferase	Chromatin/Epigenetic
	TP-064 是选择性蛋白精氨酸甲基转移酶 4 抑制剂，IC50小于10 nM，具有抗癌活性。它抑制 BAF155 和 MED12 的二甲基化，IC50为 340 和 43 nM。它对于 PRMT6 的 IC50为 1.3 μM。
T13279L	Valemetostat DS-3201	Histone Methyltransferase	Chromatin/Epigenetic
	Valemetostat (DS-3201) 是一种EZH1/2抑制剂，可用于研究复发/难治性周围 T 细胞淋巴瘤。
T5605	EZM 2302 GSK3359088	Histone Methyltransferase	Chromatin/Epigenetic
	EZM 2302 (GSK3359088) 是选择性口服精氨酸甲基转移酶 CARM1 抑制剂，IC50值为 6 nM。
T4378	MS049	Histone Methyltransferase	Chromatin/Epigenetic
	MS049 是一种有效的、选择性的和细胞活性的 PRMT4 和 PRMT6 双重抑制剂，IC50 分别为 34 和 43 nM。它可降低 HEK293 细胞的 Med12me2a 和 H3R2me2a 水平。
T11486	GSK2807 Trifluoroacetate	Histone Methyltransferase	Chromatin/Epigenetic
	GSK2807 Trifluoroacetate 是一种选择性和 SAM 竞争性的 SMYD3 抑制剂，IC50为 130 nM，Ki 值为 14 nM。
T2352	AMI-1	Histone Methyltransferase	Chromatin/Epigenetic
	AMI1 是一种有效的、可逆的、细胞渗透性的蛋白精氨酸 N-甲基转移酶 (PRMTs) 抑制剂，对人 PRMT1 和酵母 Hmt1p 作用的 IC50值分别为 8.8 和 3.0 μM。它通过阻断肽-底物结合对 PRMTs 发挥抑制作用。
T17204	UNC0321	Histone Methyltransferase	Chromatin/Epigenetic
	UNC0321 是一种有效的组蛋白甲基转移酶 G9a 抑制剂，在 ECSD 和 CLOT 测定中，Ki 为 63 pM，IC50 分别为 9 nM 和 6 nM。 UNC0321 抑制 GLP，在 ECSD 和 CLOT 试验中 IC50 分别为 15 nM 和 23 nM。
T2079	GSK126 GSK2816126A,EZH2 inhibitor	Histone Methyltransferase	Chromatin/Epigenetic
	GSK126 (GSK2816126A) 是一种 EZH2 甲基转移酶抑制剂 (IC50=9.9 nM)，具有有效性和选择性。GSK126 具有抗肿瘤活性，可以抑制肿瘤细胞增殖、抑制血管生成。
T2354	UNC 0631 UNC0631	Histone Methyltransferase	Chromatin/Epigenetic
	UNC 0631 是一种有效的组蛋白甲基转移酶 G9a 抑制剂，IC50值为 4 nM。它有效降低 MDA-MB-231 细胞中 H3K9me2的水平，IC50为 25 nM。
T6333	MM-102 MM102,HMTase Inhibitor IX	Histone Methyltransferase	Chromatin/Epigenetic
	MM-102 (HMTase Inhibitor IX) 是一种有效的 WDR5/MLL 相互作用抑制剂，在 WDR5 结合检测中，IC50为 2.4 nM，Ki 小于 1 nM。
T6360	3-deazaneplanocin A HCl	Others; Histone Methyltransferase	Chromatin/Epigenetic; Others
	3-deazaneplanocin A HCl 是组蛋白甲基转移酶 (EZH2) 和 S-腺苷同型半胱氨酸水解酶 (AHCY) 抑制剂。

化合物

Cat.No: T8548

Target: Histone Methyltransferase, Antifolate, Histamine Receptor

Cat.No: T8381

Target: Others, Histone Methyltransferase, Parasite

Cat.No: T2097

Synonym: C7280948

Target: Histone Methyltransferase

Cat.No: T5322

Target: Histone Methyltransferase

Cat.No: T3084

Target: Histone Methyltransferase

Cat.No: T1775

Target: Histone Methyltransferase

Cat.No: T4021

Target: Histone Methyltransferase

Cat.No: T1905

Target: Histone Methyltransferase

Cat.No: T9584

Target: Others, Histone Methyltransferase

Cat.No: T2435

Target: Histone Methyltransferase

Cat.No: T15624

Target: Histone Methyltransferase

Cat.No: TQ0100

Target: Histone Methyltransferase

Cat.No: T15194

Target: Histone Methyltransferase

Cat.No: T7403

Target: Histone Methyltransferase

Cat.No: T13780

Target: Apoptosis, Histone Methyltransferase

Cat.No: T15201

Target: Histone Methyltransferase

Cat.No: T6900

Target: Histone Methyltransferase

Cat.No: T7089

Target: Histone Methyltransferase

Cat.No: T10205

Target: Histone Methyltransferase

Cat.No: T3057

Target: Histone Methyltransferase, Autophagy

Cat.No: T1841

Target: Histone Methyltransferase

Cat.No: T4343

Synonym: A 196

Target: Histone Methyltransferase

Cat.No: T3081

Target: Apoptosis, Histone Methyltransferase

Cat.No: T6879

Synonym: LLY507,LLY 507

Target: Histone Methyltransferase

Cat.No: T6059

Target: Histone Methyltransferase, Autophagy

Cat.No: T36631

Target: MEK, Histone Methyltransferase

Cat.No: T3099

Synonym: EPZ-5676

Target: Histone Methyltransferase

Cat.No: T3257

Target: Influenza Virus, Histone Methyltransferase, Autophagy

Cat.No: T3458

Target: Histone Methyltransferase

Cat.No: T14841

Target: Phosphatase, P450, Histone Methyltransferase

Cat.No: T4166

Synonym: UNC-0642,UNC 0642

Target: Histone Methyltransferase

Cat.No: T40254

Target: Histone Methyltransferase

Cat.No: T13954

Target: Histone Methyltransferase, Ligands for Target Protein for PROTAC, PROTACs

Cat.No: T7378

Target: Histone Methyltransferase

Cat.No: T27133

Synonym: DCLX 069,DCLX-069

Target: Histone Methyltransferase

Cat.No: T7305

Target: Histone Methyltransferase

Cat.No: T2379

Target: Apoptosis, Epigenetic Reader Domain, Histone Methyltransferase

Cat.No: T7194

Target: Apoptosis, DNA Methyltransferase, Histone Methyltransferase

Cat.No: T12428L

Target: Histone Methyltransferase

Cat.No: T28996

Synonym: TP 064

Target: Histone Methyltransferase

Cat.No: T13279L

Synonym: DS-3201

Target: Histone Methyltransferase

Cat.No: T5605

Synonym: GSK3359088

Target: Histone Methyltransferase

Cat.No: T4378

Target: Histone Methyltransferase

GSK2807 Trifluoroacetate

Cat.No: T11486

Target: Histone Methyltransferase

Cat.No: T2352

Target: Histone Methyltransferase

Cat.No: T17204

Target: Histone Methyltransferase

Cat.No: T2079

Synonym: GSK2816126A,EZH2 inhibitor

Target: Histone Methyltransferase

Cat.No: T2354

Synonym: UNC0631

Target: Histone Methyltransferase

Cat.No: T6333

Synonym: MM102,HMTase Inhibitor IX

Target: Histone Methyltransferase

3-deazaneplanocin A HCl

Cat.No: T6360

Target: Others, Histone Methyltransferase

Cat. No.	Product Name	Target	Signaling Pathways
T8201	Gambogenic acid	Histone Methyltransferase	Chromatin/Epigenetic
	Gambogenic acid 是黄藤中的一种有效成分，具有抗癌活性。它是特异性EZH2抑制剂，与 EZH2-SET 结构域的 Cys668 位点共价结合，诱导 EZH2 泛素化。
T6803	Chaetocin 毛壳素	Histone Methyltransferase; Antibacterial; Antibiotic	Chromatin/Epigenetic; Microbiology/Virology
	Chaetocin 特异性抑制组蛋白甲基转移酶(HMT) SU(VAR)3-9，IC50值为0.6 μM。它还可抑制硫氧还蛋白还原酶，IC50值为4 μM。

天然产物

Gambogenic acid

Cat.No: T8201

Target: Histone Methyltransferase

Cat.No: T6803

Synonym: 毛壳素

Target: Histone Methyltransferase, Antibacterial, Antibiotic

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01708	DOT1L Protein, Human, Recombinant DOT1,KMT4,DOT1-like histone H3K79 methyltransfe...	Human	E. coli
	Histone-lysine N-methyltransferase, H3 lysine-79 specific, also known as Histone H3-K79 methyltransferase, DOT1-like protein, Lysine N-methyltransferase 4 and DOT1L, is a nucleus protein which belongs to theDOT1 family. In contrast to other lysine histone methyltransferase, DOT1L does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones. DOT1L is an histone methyltransferase. It methylates 'Lys-79' of histone H3. Nucleosome...
TMPH-02105	ASH2L Protein, Human, Recombinant (His & SUMO) ASH2-like protein,ASH2L,ASH2L1,Set1/Ash2 histone	Human	E. coli
	Transcriptional regulator. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters. Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May p...
TMPH-01526	KMT2E Protein, Human, Recombinant (His & Myc) Inactive histone-lysine N-methyltransferase	Human	E. coli
	Associates with chromatin regions downstream of transcriptional start sites of active genes and thus regulates gene transcription. Chromatin interaction is mediated via the binding to tri-methylated histone H3 at 'Lys-4' (H3K4me3). Key regulator of hematopoiesis involved in terminal myeloid differentiation and in the regulation of hematopoietic stem cell (HSCs) self-renewal by a mechanism that involves DNA methylation. Also acts as an important cell cycle regulator, participating in cell cycle r...
TMPH-01484	SMYD3 Protein, Human, Recombinant (His & Myc) Zinc finger MYND domain-containing protein 1,SMYD3,SET and M...	Human	E. coli
	SMYD3 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPY-01229	SETD7 Protein, Human, Recombinant (His) SET7/9,SET domain containing (lysine methyltransferase	Human	E. coli
	Histone-lysine N-methyltransferase SETD7, also known as SET domain containing (lysine methyltransferase) 7, SET7/9, Histone H3-K4 methyltransferase SETD7, H3-K4-HMTase SETD7, and SETD7, is a member of the histone-lysine methyltransferase family and SET7 subfamily. SETD7 is widely expressed and expressed in pancreatic islets. SETD7 contains three MORN repeats and one SET domain. SETD7 plays a central role in the transcriptional activation of genes such as collagenase or insulin. As a protein lysi...
TMPY-01657	SUV420H2 Protein, Human, Recombinant (His & GST) suppressor of variegation 4-20 homolog 2 (Drosophila),KMT5C	Human	E. coli
	Histone-lysine N-methyltransferase SUV42H2, also known as Suppressor of variegation 4-2 homolog 2, Su(var)4-2 homolog 2, Lysine N-methyltransferase 5C, SUV42H2 and KMT5C, is nucleus protein that belongs to the histone-lysine methyltransferase family and Suvar4-2 subfamily. SUV42H2 is a histone methyltransferase that specifically trimethylates 'Lys-2' of histone H4. H4 'Lys-2' trimethylation represents a specific tag for epigenetic transcriptional repression. SUV42H2 mainly functions in pericentr...
TMPH-02227	ERG Protein, Human, Recombinant (His) Transcriptional regulator ERG,Transforming protein ERG,ERG	Human	P. pastoris (Yeast)
	Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure. ERG Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 56.6 kDa and the accession number is P11308.
TMPY-01383	PRMT6 Protein, Human, Recombinant (His & Flag) protein arginine methyltransferase 6,HRMT1L6	Human	HEK293 Cells
	Protein arginine N-methyltransferase 6, also known as Histone-arginine N-methyltransferase PRMT6, PRMT6, and HRMT1L6, is a member of the protein arginine N-methyltransferase family and PRMT6 subfamily. PRMT6 is highly expressed in kidney and testes. PRMT6 is known to catalyze the generation of asymmetric dimethylarginine in polypeptides. It has been implicated in human immunodeficiency virus pathogenesis, DNA repair, and transcriptional regulation. PRMT6 is known to methylate histone H3 Arg-2 (H...
TMPY-01268	SMYD3 Protein, Human, Recombinant (GST) SET and MYND domain containing 3,ZMYND1,KMT3E,ZNFN3A1,bA74P1...	Human	Baculovirus Insect Cells
	SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger and one SET domain. SMYD3 is a histone H3 lysine-4-specific methyltransferase. It is expressed in skeletal muscles and testis. It is overexpressed in a majority of colorectal carcinoma (CRC) and hepatocellular carcinoma (HCC). SMYD3 plays an important role in transcriptional reg...
TMPY-04403	NLK/Nemo Like Kinase Protein, Human, Recombinant (His & GST) nemo-like kinase,LAK1	Human	Baculovirus Insect Cells
	Nemo-like kinase contains 1 protein kinase domain and belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, and MAP kinase subfamily. It also contains a TQE activation loop motif in which autophosphorylation of the threonine residue (Thr-298) is sufficient for kinase activation. As a serine/threonine-protein kinase, Nemo-like kinase regulates some transcription factors with key roles in cell fate determination. It is a positive effector of the non-canonical Wnt signaling...
TMPJ-01040	MAX Protein, Human, Recombinant (His) Protein Max,MAX,bHLHd4,Myc-Associated Factor X,Class D Basic...	Human	E. coli
	Myc-Associated Factor X (MAX) is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It contains 1 basic helix-loop-helix (bHLH) domain. It is found in the brain, heart, and lung at high levels while lower levels are seen in the liver, kidney, and skeletal muscle. MAX forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC-MAX complex is a transcriptional activator, whereas the MA...
TMPY-02888	MAX Protein, Human, Recombinant (His & GST) MYC associated factor X,bHLHd4	Human	Baculovirus Insect Cells
	MYC associated factor X contains 1 basic helix-loop-helix (bHLH) domain and belongs to the MAX family. It is highly expressed in the brain, heart, and lung while lower levels are seen in the liver, kidney, and skeletal muscle. MYC associated factor X can form homodimers and heterodimers with other family members, which include Mad, Mxi1, and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation, and apoptosis. The homodimers and heterodimers compete for a common DNA target...

重组蛋白

DOT1L Protein, Human, Recombinant

Cat.No: TMPY-01708

Species: Human

Expression System: E. coli

ASH2L Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02105

Species: Human

Expression System: E. coli

KMT2E Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01526

Species: Human

Expression System: E. coli

SMYD3 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01484

Species: Human

Expression System: E. coli

SETD7 Protein, Human, Recombinant (His)

Cat.No: TMPY-01229

Species: Human

Expression System: E. coli

SUV420H2 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-01657

Species: Human

Expression System: E. coli

ERG Protein, Human, Recombinant (His)

Cat.No: TMPH-02227

Species: Human

Expression System: P. pastoris (Yeast)

PRMT6 Protein, Human, Recombinant (His & Flag)

Cat.No: TMPY-01383

Species: Human

Expression System: HEK293 Cells

SMYD3 Protein, Human, Recombinant (GST)

Cat.No: TMPY-01268

Species: Human

Expression System: Baculovirus Insect Cells

NLK/Nemo Like Kinase Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04403

Species: Human

Expression System: Baculovirus Insect Cells

MAX Protein, Human, Recombinant (His)

Cat.No: TMPJ-01040

Species: Human

Expression System: E. coli

MAX Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02888

Species: Human

Expression System: Baculovirus Insect Cells

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