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TMPH-03699
|
VSIV (strain 94GUB Central America) L Protein (His)
RNA-directed RNA polymerase L,Replicase,Transcriptase,L,Larg...
|
VSIV
|
E. coli
|
|
VSIV (strain 94GUB Central America) L Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25.4 kDa and the accession number is Q8B0H0. |
|
TMPY-05054
|
Notch 4 Protein, Human, Recombinant (His)
INT3,notch 4
|
Human
|
Baculovirus Insect Cells
|
|
NOTCH4 (Notch Receptor 4) is a Protein Coding gene. Notch4 belongs to a family of transmembrane receptors that play an important role in vascular development and maintenance. The NOTCH4 gene is located at 6p21.3 and is involved in the development and patterning of the central nervous systems. It regulates signaling pathways associated with neuronal maturation, a process involved in the development and patterning of the central nervous system. The NOTCH4 gene has also been identified as a possibl... |
|
TMPK-01150
|
Beta Klotho Protein, Mouse, Recombinant (His)
Klotho beta,β-klotho,MGC142213,βKlotho,β Klotho,KLB,beta-klo...
|
Mouse
|
HEK293 Cells
|
|
Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites. Beta Klotho Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 109.91 kDa and the acce... |
|
TMPK-00369
|
HGF Protein, Human, Recombinant (hFc)
HGF,F-TCF,HGFB,SF,F-TCFB,肝细胞生长因子,DFNB39,Hepatopoietin-A,HPTA
|
Human
|
HEK293 Cells
|
|
Hepatocyte growth factor (HGF) is an important component of the pathophysiology of IR, with increased levels in most common IR conditions, including obesity. HGF has a role in the metabolic flux of glucose in different insulin sensitive cell types; plays a key role in β-cell homeostasis; and is capable of modulating the inflammatory response.HGF plays a central role in these metabolic disorders,HGF levels could be employed as a biomarker for disease status/progression, and HGF/c-Met signaling pa... |
|
TMPY-02525
|
RGMA Protein, Human, Recombinant (His)
repulsive guidance molecule family member a,RGM
|
Human
|
HEK293 Cells
|
|
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that form... |
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TMPJ-00651
|
CD155/PVR Protein, Human, Recombinant (aa 21-343, His)
Poliovirus Receptor,PVS,Nectin-Like Protein 5,NECL-5,CD155,P...
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Human
|
HEK293 Cells
|
|
Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains, a transmembrane segment, and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension be... |
|
TMPJ-00562
|
PDGF-BB Protein, Mouse, Recombinant (His)
PDGFBB,PDGF-BB,血小板源生长因子
|
Mouse
|
E. coli
|
|
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. As growth factor，it plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival... |
|
TMPY-04329
|
Vimentin Protein, Human, Recombinant (His)
CTRCT30,HEL113,vimentin
|
Human
|
Baculovirus Insect Cells
|
|
Vimentin is a type III intermediate filament (IF) protein found in various non-epithelial cells, especially mesenchymal cells. A vimentin monomer, has a central α-helical domain and carboxyl (tail) domains. Two monomers compose the basic subunit of vimentin assembly. Vimentin is crucial for supporting and anchoring the position of the organelles in the cytosol. Vimentin provided cells with a resilience absent from the microtubule or actin filament networks, when under mechanical stress in vivo. ... |
|
TMPJ-01430
|
NovoNectin Protein, Human, Recombinant
NovoNectin,Cold-insoluble globulin,FN,CIG,Fibronectin,Fibron...
|
Human
|
E. coli
|
|
Fibronectin1(FN1) is a secreted protein and contains 12 fibronectin type-I domains,fibronectin type-II domains and 16 fibronectin type-III domains.Recombinant human fibronectin fragment, is a protein of ~63 kDa containing a central cell-binding domain, a high affinity heparin-binding domain II,and CS1 site within the alternatively spliced III CS region of human fibronectin. Cells bind to a VLA-4 ligand, a CS-I site, and a VLA-5 ligand, a cell attachment domain, and virus vectors binds to a hepar... |
|
TMPY-03425
|
Tau Protein, Human, Recombinant (His)
PPND,FTDP-17,MTBT1,DDPAC,MAPTL,MTBT2,microtubule-associated ...
|
Human
|
E. coli
|
|
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP... |
|
TMPY-02603
|
STAT6 Protein, Human, Recombinant (His)
STAT6C,IL-4-STAT,STAT6B,signal transducer and activator of t...
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Human
|
Baculovirus Insect Cells
|
|
Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6 plays a central role in exerting interleukin-4 (IL-4) mediated biological responses and is found to induce the expression of BCL2L1/BCL-XL, which is responsible for the anti-apoptotic activity of IL4. Transcriptional activation by STAT6 requires the interaction with coactivators... |
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TMPY-02580
|
Histone H1 Protein, Human, Recombinant (His)
HSP60,HSP65,CPN60,H1 histone family, member 0,H10,HLD4,HSPD1...
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Human
|
E. coli
|
|
H1 histone family, member 0 (H1F0) is a member of the H1 histone family of nuclear proteins which are a component of chromatin in eukaryotic cells. It's involved in maintaining the structure of chromatin by packing the "beads on a string" sub-structure into a high order structure. The lysine-rich H1 histone family in mammals includes eleven members. In higher eukaryotes, all H1 variants have the same general structure, consisting of a central conserved globular domain and less conserved N-termin... |
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TMPY-05510
|
BDNF Protein, Mouse, Recombinant (His)
brain-derived neurotrophic factor
|
Mouse
|
HEK293 Cells
|
|
BDNF is a member of thenerve growth factorfamily. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. It participates in axonal growth,... |
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TMPJ-01466
|
Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)
OPG,Tumor Necrosis Factor Receptor Superfamily Member 11B,OC...
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Human
|
HEK293 Cells
|
|
TNFRSF11B is a secreted protein, containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits nuclear kappa B (NF-κB) which is a central and rapid acting transcription factor for immune-related genes, and a key regulator of inflammation, innate immunity, and cell survival and differentiation. TNFRSF11B levels are influenced by voltage-dependent calcium channelsCav1.2. TNF... |
|
TMPY-02543
|
PCNA Protein, Human, Recombinant (His)
ATLD2,proliferating cell nuclear antigen
|
Human
|
Baculovirus Insect Cells
|
|
Proliferating Cell Nuclear Antigen (PCNA) is a protein only expressed in normal proliferate cells and cancer cells. It is central to both DNA replication and repair. One of the well-established functions for PCNA is its role as the processivity factor for DNA polymerase delta and epsilon. PCNA tethers the polymerase catalytic unit to the DNA template for rapid and processive DNA synthesis. Two forms of PCNA exist in cells: (i) a detergent-insoluble trimeric form stably associated with the replic... |
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TMPY-02030
|
CD82 Protein, Human, Recombinant (His)
CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,TSPAN27,ST6,IA4,GR1...
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Human
|
HEK293 Cells
|
|
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud... |
|
TMPJ-01065
|
Noggin/NOG Protein, Mouse, Recombinant (His)
Nog,Noggin
|
Mouse
|
HEK293 Cells
|
|
Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal peptide that is cleaved to generate the 213 aa residue mature protein which is secreted as a homodimeric glycoprotein. Secreted Noggin probably remains close to the cell surface due to its binding of heparin-containing proteoglycans. Noggin binds some BMPs such as BMP4 with high affi... |
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TMPJ-00375
|
HGF Protein, Human, Recombinant (His)
Scatter factor,Hepatocyte growth factor,HGF,SF,Hepatopoietin...
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Human
|
HEK293 Cells
|
|
HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases and contains 4 kringle domains, 1 PAN domain and 1 peptidase S1 domain. HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. It is cleaved after the fourth Kringle domain by a serine protease to form bioactive disulfide-linked HGF with a 60 kDa alpha and 30 kDa beta chain. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelia... |
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TMPY-01813
|
ACRV1 Protein, Human, Recombinant (His)
SP-10,SPACA2,D11S4365,acrosomal vesicle protein 1
|
Human
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HEK293 Cells
|
|
Acrosomal protein SP-1, also known as Acrosomal vesicle protein 1 and ACRV1, is a testis-specific, differentiation antigen, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. Regulation of cell type-specific gene transcription is central to cellular differentiation and development. During spermatogenesis, a number of testis-specific genes are expressed in a precise spatiotemporal order. The longest tr... |
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TMPY-01442
|
DMBT1 Protein, Human, Recombinant (His)
GP340,deleted in malignant brain tumors 1,muclin
|
Human
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HEK293 Cells
|
|
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are invo... |
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TMPY-01101
|
Coagulation factor X/F10 Protein, Human, Recombinant (His)
FXA,FX,coagulation factor X,coagulation factor 10
|
Human
|
Baculovirus Insect Cells
|
|
Coagulation factor X, also known as FX, F10, Eponym Stuart-Prower factor, and thrombokinase, is an enzyme of the coagulation cascade. It is one of the vitamin K-dependent serine proteases, and plays a crucial role in the coagulation cascade and blood clotting, as the first enzyme in the common pathway of thrombus formation. Factor X deficiency is one of the rarest of the inherited coagulation disorders. FX deficiency among the most severe of the rare coagulation defects, typically including hema... |
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TMPH-00508
|
Pro-resilin Protein, Drosophila melanogaster, Recombinant (His & Myc)
Pro-resilin,resilin
|
Fruit fly
|
E. coli
|
|
Plays a central role in insect flight by providing low stiffness, high strain and efficient energy storage. |
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TMPH-02530
|
ATP5B Protein, Mouse, Recombinant (His & Myc & SUMO)
ATP synthase F1 subunit beta,Atp5b,Atp5f1b,ATP synthase subu...
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Mouse
|
E. coli
|
|
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain ... |
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TMPH-02653
|
FGF-20 Protein, Mouse, Recombinant
Fgf20,Fibroblast growth factor 20
|
Mouse
|
E. coli
|
|
Neurotrophic factor that regulates central nervous development and function. FGF-20 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 23.6 kDa and the accession number is Q9ESL9. |
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TMPY-00561
|
Neurotensin Protein, Human, Recombinant (hFc)
NMN-125,NTS1,NN,NT/N,neurotensin,NT
|
Human
|
HEK293 Cells
|
|
NTS (Neurotensin) is a Protein Coding gene. This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. NTS is a neuropeptide distributed in the central nervous and digestive systems. It belongs to the neurotensin family. NTS is an endogenous tridecapeptide of the central nervous system and the gastrointestinal tract of different mammalian species including the human. The human gene encoding neurotensin has previously been assigned to chromosome 12 but no regional locali... |
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TMPH-01622
|
KDM3B Protein, Human, Recombinant (His & Myc & SUMO)
[histone H3]-dimethyl-L-lysine(9) demethylase 3B,Lysine-spec...
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Human
|
E. coli
|
|
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. |
|
TMPH-02685
|
GPHB5 Protein, Mouse, Recombinant (His & Myc)
Glycoprotein hormone beta-5,Thyrostimulin subunit beta,Gphb5
|
Mouse
|
E. coli
|
|
Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid cell metabolism. |
|
TMPH-00073
|
ADH2 Protein, Arabidopsis thaliana, Recombinant (His)
GSH-FDH,Glutathione-dependent formaldehyde dehydrogenase,Alc...
|
Arabidopsis thaliana
|
E. coli
|
|
Plays a central role in formaldehyde detoxification. ADH2 Protein, Arabidopsis thaliana, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 44.7 kDa and the accession number is Q96533. |
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TMPH-02674
|
GFAP Protein, Mouse, Recombinant
Gfap,Glial fibrillary acidic protein
|
Mouse
|
Baculovirus Insect Cells
|
|
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. |
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TMPH-02673
|
GFAP Protein, Mouse, Recombinant (His & SUMO)
Glial fibrillary acidic protein,Gfap
|
Mouse
|
E. coli
|
|
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. |
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TMPH-02988
|
UGPA Protein, Musa acuminata, Recombinant (His & Myc)
UGPA,UDP-glucose pyrophosphorylase,UTP--glucose-1-phosphate ...
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Musa acuminata
|
E. coli
|
|
Plays a central role as a glucosyl donor in cellular metabolic pathways. UGPA Protein, Musa acuminata, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 58.8 kDa and the accession number is Q9SDX3. |
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TMPJ-00295
|
NgR Protein, Mouse, Recombinant (hFc)
Nogo-66 Receptor,Nogo Receptor,NgR,RTN4R,NOGOR,Reticulon-4 R...
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Mouse
|
HEK293 Cells
|
|
Nogo Receptor (NgR) is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family. Human NgR is predominantly expressed in neurons and their axons in the central nervous systems. As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG) and myelin oligodendrocyte glycoprotein (OMG), NgR mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. NgR may be prop... |
|
TMPK-01381
|
CSPG4/MCSP Protein, Cynomolgus, Recombinant (His)
MCSPG,CSPG4,MCSP,NG2
|
Cynomolgus
|
HEK293 Cells
|
|
The chondroitin sulfate proteoglycan-4 (CSPG4) is a cell surface proteoglycan overexpressed in a huge range of human and canine neoplastic lesions by tumor cells, tumor microenvironment and cancer initiating cells. CSPG4 plays a central role in the oncogenic pathways required for malignant progression and metastatization. |
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TMPH-02861
|
Wnt7b Protein, Mouse, Recombinant (His & Myc & SUMO)
Wnt7b,Protein Wnt-7b
|
Mouse
|
E. coli
|
|
Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal fusion of the chorion and the allantois during placenta development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation. |
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TMPH-02684
|
GPHB5 Protein, Mouse, Recombinant (His)
Thyrostimulin subunit beta,Glycoprotein hormone beta-5,Gphb5
|
Mouse
|
P. pastoris (Yeast)
|
|
Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid cell metabolism. GPHB5 Protein, Mouse, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 13.3 kDa and the accession number is Q812B2. |
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TMPY-00286
|
Neuropeptide Y Protein, Human, Recombinant (hFc)
PYY4,neuropeptide Y
|
Human
|
HEK293 Cells
|
|
NPY (Neuropeptide Y) is a Protein Coding gene. This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. NPY is a neuromodulator that is widely expressed throughout the central nervous system (CNS) and is consecrated with classic neurotransmitters including GABA and glutamate. NPY/Agouti-related protein (AgRP) ne... |
|
TMPJ-00846
|
GFAP Protein, Human, Recombinant (His)
Glial Fibrillary Acidic Protein,GFAP
|
Human
|
E. coli
|
|
Glial Fibrillary Acidic Protein (GFAP) is an intermediate filament (IF) protein which belongs to the intermediate filament family. GFAP is expressed in numerous cell types of the central nervous system (CNS), ependymal cells and phosphorylated by PKN1. GFAP, a class-III intermediate filament, is a cell-specific marker during the development of the central nervous system and distinguishes astrocytes from other glial cells. It is closely related to its non-epithelial family members, vimentin, desm... |
|
TMPH-01859
|
PISD Protein, Human, Recombinant (His & SUMO)
PISD,Phosphatidylserine decarboxylase proenzyme, mitochondri...
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Human
|
E. coli
|
|
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. PISD Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 56.0 kDa and the accession number is Q9UG56. |
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TMPH-01504
|
HAPLN2 Protein, Human, Recombinant (His)
Hyaluronan and proteoglycan link protein 2,HAPLN2,Brain link...
|
Human
|
E. coli
|
|
Mediates a firm binding of versican V2 to hyaluronic acid. May play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS) which facilitates neuronal conduction and general structural stabilization. Binds to hyaluronic acid. |
|
TMPH-03292
|
FGF-20 Protein, Rat, Recombinant (His & Myc)
Fibroblast growth factor 20,Fgf20
|
Rat
|
E. coli
|
|
Neurotrophic factor that regulates central nervous development and function. May play an important role in dopaminergic neurons in the substantia nigra. FGF-20 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 31.0 kDa and the accession number is Q9EST9. |
|
TMPH-01722
|
PLP1 Protein, Human, Recombinant (His)
Lipophilin,Myelin proteolipid protein,PLP1
|
Human
|
E. coli
|
|
This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin. PLP1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 35.5 kDa and the accession number is P60201. |
|
TMPH-02489
|
ASCL2 Protein, Mouse, Recombinant (His & Myc)
mASH2,Achaete-scute homolog 2,ASH-2,mASH-2,Ascl2,Mash2
|
Mouse
|
E. coli
|
|
AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. ASCL2 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 32.8 kDa and the accession number is O35885. |
|
TMPH-02380
|
RPB5 Protein, Kluyveromyces marxianus, Recombinant (His)
RPB5,DNA-directed RNA polymerases I, II, and III subunit RPA...
|
Kluyveromyces marxianus
|
E. coli
|
|
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol... |
|
TMPH-01646
|
MMP-20 Protein, Human, Recombinant (His & Myc)
Enamel metalloproteinase,Matrix metalloproteinase-20,MMP20,E...
|
Human
|
Baculovirus Insect Cells
|
|
Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation. Cleaves aggrecan at the '360-Asn-|-Phe-361' site. |
|
TMPH-01647
|
MMP-20 Protein, Human, Recombinant (E. coli, His & Myc)
Matrix metalloproteinase-20,Enamelysin,Enamel metalloprotein...
|
Human
|
E. coli
|
|
Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation. Cleaves aggrecan at the '360-Asn-|-Phe-361' site. |
|
TMPH-01404
|
PYGL Protein, Human, Recombinant (GST)
Glycogen phosphorylase, liver form,PYGL
|
Human
|
E. coli
|
|
Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis. PYGL Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 123.9 kDa and the accession number is P06737. |
|
TMPY-01120
|
VPAC2 Protein, Human, Recombinant (mFc)
VPCAP2R,PACAP-R-3,VIP-R-2,vasoactive intestinal peptide rece...
|
Human
|
HEK293 Cells
|
|
VIP and PACAP receptor 2, or VIPR2 encodes the VPAC2 receptor, which binds both VIP and PACAP. VPAC2 is expressed throughout the central nervous system and the periphery. Mutations in the VIPR2 homolog in the mouse cause hypoactivity, as well as disruptions in circadian rhythm. Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia. |
|
TMPH-02252
|
TPM3 Protein, Human, Recombinant (GST)
Gamma-tropomyosin,Tropomyosin alpha-3 chain,Tropomyosin-3,TP...
|
Human
|
E. coli
|
|
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. |
|
TMPK-00279
|
RGMA Protein, Human, Recombinant (His & Avi), Biotinylated
RGM,RGMA
|
Human
|
HEK293 Cells
|
|
Repulsive guidance molecule (RGM) is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that has diverse functions in the developing and pathological central nervous system (CNS). The binding of RGM to its receptor neogenin regulates axon guidance, neuronal differentiation, and survival during the development of the CNS. RGMa induces T cell activation in experimental autoimmune encephalomyelitis (EAE), which is the animal model of multiple sclerosis (MS). |
|
TMPK-00861
|
A2AR Protein-VLP, Human, Recombinant
RDC8,Adenosine A2a R,ADORA2,ADORA 2,ADORA2A,A2aR
|
Human
|
HEK293 Cells
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Adenosine is a neuromodulator in the adult central nervous system. Membrane-bound receptors for adenosine have been identified and cDNAs for A1, A2a, A2b, and A3 adenosine receptor subtypes have been cloned recently.Expression of A2a adenosine receptor mRNA in cranial ganglia, carotid body, and intermediate lobe of the pituitary gland similarly suggests novel sites of adenosine action during development and in the adult. |
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