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Targets Recommended: Opioid Receptor

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Cat. No. Product Name
L7810 高溶解性多官能团片段化合物库

1159 compounds
高溶解性多官能团片段库包含1159 种片段分子

化合物库

高溶解性多官能团片段化合物库
Cat.No: L7810
Compounds: 1159
Cat. No. Product Name Target Signaling Pathways
TP1254 [Met5]-Enkephalin, amide TFA

5-Methionine-enkephalin amide (TFA)

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
[Met5]-Enkephalin, amide TFA (5-Methionine-enkephalin amide (TFA)) (60117-17-1 free base) 是一种 δ 阿片受体激动剂以及推定的 ζ (zeta) opioid 受体。
TP1113L [Leu5]-Enkephalin, amide acetate

[Leu5]-Enkephalin, amide acetate(60117-24-0 free base)

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
[Leu5]-Enkephalin, amide acetate 是一种 δ 阿片受体激动剂。
TP1250L Acetyl-PHF6 amide acetate

Acetyl-PHF6 amide acetate(878663-43-5 free base),AcPHF6 acetate,Ac-VQIVYK-NH2 acetate

Others Others
Acetyl-PHF6 amide acetate(878663-43-5 freebase) (AcPHF6 acetate) 是一种 tau 衍生的六肽。
TP1378 2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base)

2-Furoyl-LIGRLO-amide

Protease-activated Receptor GPCR/G Protein
2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base) 是一种有效的选择性蛋白酶激活受体 2 (PAR2) 激动剂。
T21983L PKI 14-22 amide, myristoylated Acetate

PKI 14-22 amide, myristoylated Acetate(201422-03-9 Free base)

PKA Tyrosine Kinase/Adaptors
PKI 14-22 amide, myristoylated Acetate 抑制 cAMP 依赖性蛋白激酶 (PKA) 并阻断脊髓给药 8-溴-cAMP 产生的痛觉过敏。
T3984 GLP-1(7-36), amide

MKC 253,胰高血糖素样肽-1,Human GLP-1-(7-36)-amide,Glucagon-like Peptide 1 (7-36) amide,Glucagon-Like Peptide (GLP) I (7-36), amide, human,GLP-1(7-36),GLP-1-(7-36)-amide

Glucagon Receptor GPCR/G Protein
GLP-1(7-36), amide (MKC 253) 是一种生理性肠降血糖素,能够刺激胰岛素分泌。
TP1002L γ-1-MSH, amide acetate (72629-65-3 free base)

γ-1-MSH, amide acetate

Others Others
γ-1-MSH, amide acetate (72629-65-3 free base) 是 ACTH/β-内啡肽 (β-EP) 前体蛋白 N 末端区域的一种推定激素,RIA 使用抗 γ-3-MSH 抗血清对产生 ACTH 的小鼠进行了研究垂体肿瘤细胞,AtT-20/D16v。
TP2446L Angiotensin amide acetate

血管紧张素胺,Angiotensin amide acetate(53-73-6 Free base)

Others Others
Angiotensin amide acetate 是Angiotensin amide 的衍生物。Angiotensin amide 是一种八肽酰胺,可以通过血管收缩来提高血压。
TP1858L Phe-Met-Arg-Phe, amide acetate

Phe-Met-Arg-Phe, amide acetate(64190-70-1 freebase)

Potassium Channel Membrane transporter/Ion channel
Phe-Met-Arg-Phe, amide acetate(64190-70-1 freebase) 剂量依赖性 (ED50=23 nM) 激活肽能尾背神经元中的 K+ 电流。这种肽似乎在大脑的某些区域与神经肽 Y 一起定位。
T0643 Diclofenac Amide

Others Others
Diclofenac Amide 用作Diclofenac 的中间体。
T37891L GLP-1(32-36)amide acetate

GLP-1(32-36)amide 醋酸盐,GLP-1(32-36)amide acetate(1417302-71-6 Free base)

Others Others
GLP-1(32-36)amide acetate 是一种五肽,衍生自糖调节激素 GLP-1 的 C 末端。GLP-1(32-36)amide acetate 可抑制糖尿病小鼠的体重增加并调节全身葡萄糖代谢。
T38852L TRAP-6 amide acetate

Protease-activated Receptor GPCR/G Protein
TRAP-6 amide acetate 是一种 PAR-1 凝血酶受体激动剂肽。
T75888 PKA Inhibitor Fragment (6-22) amide TFA

PKI-(6-22)-amide TFA,PKA Inhibitor Fragment (6-22) amide TFA(121932-06-7 Free base)

PKA Tyrosine Kinase/Adaptors
PKA Inhibitor Fragment (6-22) amide TFA (PKA Inhibitor Fragment (6-22) amide TFA) 是抑制高效 cAMP 依赖性蛋白激酶 A (PKA)抑制剂(Ki:2.8 nM)。PKA Inhibitor Fragment (6-22) amide TFA 可逆转小鼠低水平的吗啡缓解疼痛的作用。
T37890L GLP-1(28-36)amide acetate

GLP-1(28-36)amide acetate(1225021-13-5 Free base)

Antioxidant; Glucagon Receptor GPCR/G Protein; oxidation-reduction
GLP-1(28-36)amide acetate 抑制线粒体通透性转变,具有抗氧化、抗糖尿病和心脏保护活性。
TP1793L Nociceptin (1-13) amide TFA

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
Nociceptin (1-13) amide TFA (178064-02-3 free base) 是一种有效的 Opioid receptor-like1 (ORL1) receptor 激动剂,对小鼠输精管的 pEC50 为 7.9,与大鼠前脑膜结合的 Ki 为 0.75 nM。
T21674L PKA inhibitor fragment (6-22) amide Acetate

PKA inhibitor fragment (6-22) amide Acetate(121932-06-7 Free base)

PKA Tyrosine Kinase/Adaptors
PKA inhibitor fragment (6-22) amide Acetate 是一种通过结合底物位点选择性抑制PKA 活性的合成肽(IC50 < 2 nM)。
T9417L gamma-preprotachykinin amide (72-92) acetate

gamma-preprotachykinin amide (72-92) acetate (114882-65-4 Free base)

Others Others
gamma-preprotachykinin amide (72-92) acetate 是一种 21 个氨基酸的肽,属于速激肽 (TK) 家族,在其 C 末端序列中包括神经激肽 A (NKA)。它对中枢 NK-2 受体的亲和力高于 NKA;它对 NK-1 受体的亲和力较低,但是,它有效地刺激唾液分泌,这是由 NK-1 受体激活介导的。
T5518 N-acetylcysteine amide

Reactive Oxygen Species; ROS Immunology/Inflammation; Metabolism; NF-κB
N-Acetylcysteine amide 是一种硫醇抗氧化剂,也是一种神经保护剂,能够透过细胞膜和血脑屏障的,可降低ROS 的产生。
T38063 N-Acetyl lysyltyrosylcysteine amide

Glutathione Peroxidase Metabolism
N-Acetyl lysyltyrosylcysteine amide 是一种无毒的髓过氧化物酶 (MPO) 三肽抑制剂,具有有效性,可逆性和特异性。N-Acetyl lysyltyrosylcysteine amide 在体内可有效抑制 MPO 产生。N-Acetyl lysyltyrosylcysteine amide 减轻中风后大脑的神经元损伤,并保留脑组织和神经功能。N-Acetyl lysyltyrosylcysteine amide 抑制MPO依赖性次氯酸 (HOCl) 的生成,蛋白质硝化和 LDL 氧化。N-Acetyl lysyltyrosylcysteine amide 可用于研究支气管发育不良。
T37588L GIP (1-30) amide, porcine acetate

IGF-1R Tyrosine Kinase/Adaptors
GIP (1-30) amide, porcine acetate 是完全葡萄糖依赖性促胰岛素多肽 (GIP) 受体的激动剂。它可弱抑制胃酸分泌,强烈刺激胰岛素。
TP2252 GLP-1 (9-36) amide

Glucagon Receptor GPCR/G Protein
GLP-1(9-36)amide 是胰高血糖素样肽-1 (7-36) amide 的主要代谢产物,对人胰腺 GLP-1受体具有拮抗作用。
TP1140L Neuropeptide Y (29-64), amide, human acetate

Neuropeptide Y Receptor GPCR/G Protein; Neuroscience
Neuropeptide Y (29-64), amide, human acetate 参与阿尔茨海默病 (AD) 并保护大鼠皮质神经元免受 β-淀粉样蛋白毒性。
TP2212L a-MSH, amide Acetate(581-05-5 free base)

Melanocortin Receptor GPCR/G Protein; Neuroscience
a-MSH, amide Acetate(581-05-5 free base) 是一种内源性黑皮质素受体 4 (MC4R) 激动剂,具有抗炎和解热活性。 α-MSH 是阿片黑皮质素原 (POMC) 的翻译后衍生物。
TP1065 PAR-4 Agonist Peptide, amide TFA

PAR-4-AP (TFA),AY-NH2 (TFA)

Protease-activated Receptor GPCR/G Protein
PAR-4 Agonist Peptide, amide TFA (PAR-4-AP (TFA)) 是一种蛋白酶激活受体 4 (PAR-4) 激动剂,对 PAR-1 或 PAR-2 均无影响,其作用可被 PAR-4 拮抗剂阻断。
T17580 Biotin-PEG4-Amide-C6-Azide

生物素-四聚乙二醇-氨基-C6-叠氮

Others; PROTAC Linker Others; PROTAC
Biotin-PEG4-Amide-C6-Azide 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。
T7513 Protease-Activated Receptor-2, amide

蛋白酶活化的受体-2,酰胺,SLIGKV-NH2,H-丝氨酰亮氨酰异亮氨酰甘氨酰赖氨酰缬氨酰NH2

Protease-activated Receptor GPCR/G Protein
Protease-Activated Receptor-2, amide (SLIGKV-NH2) 是 PAR2 的激动剂,IC50为 10.4 M。
T85009 Betulinic glycine amide

Betulinic glycine amide

Others Others
Betulinic glycine amide, a pentacyclic triterpenoid derivative of betulinic acid, serves as a precursor for synthesizing derivatives with anticancer and antiviral activity.
T35326 Labetalone hydrochloride

Labetalone hydrochloride,Benzoic amide

Others; Adrenergic Receptor GPCR/G Protein; Neuroscience; Others
Labetalone hydrochloride 是一种口服有效的肾上腺素能受体阻断药物,对 α 和 β 受体部位都有竞争性拮抗作用。
T25474 GW-Amide

Glycyl-tryptophanamide,GW Amide

Others Others
GW-Amide is a molluscan neuropeptide that exhibits potent modulatory effects on molluscan muscles.
TP1183 Amylin, amide, human

DAP amide, human

Amylin, a 37-amino acid polypeptide that is structurally related to calcitonin, is secreted from the B cells of the pancreas. Amylin has anoretic effects in rats. Amylin may be responsible for the etiology of insulin resistance of type II diabetes mellitu
T9691L (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate

Thyroid hormone receptor(THR) Endocrinology/Hormones
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate 是一种高效的甲状旁腺激素 (PTH) 拮抗剂,在牛肾皮质膜中的 Ki 值为 69 nM。
TP1255 [Met5]-Enkephalin, amide

5-Methionine-enkephalin amide

[Met5]-Enkephalin, amide is an agonist for δ opioid receptors as well as putative ζ (zeta) opioid receptors.Met-enkephalin circulates in several forms, some of which may be derived from proteins other than proenkephalin A, and plasma levels of both free n
T35473 A 410099.1 amide-PEG5-amine

A 410099.1 amide-PEG5-amine

Others Others
Functionalized IAP ligand for PROTAC research and development; incorporates an IAP ligand plus an amide-PEG5 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T35471 A 410099.1 amide-PEG3-amine

A 410099.1 amide-PEG3-amine

Others Others
Functionalized IAP ligand for PROTAC research and development; incorporates an IAP ligand plus a short amide-PEG linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T35469 A 410099.1 amide-alkylC4-amine

A 410099.1 amide-alkylC4-amine

Others Others
Functionalized IAP ligand for PROTAC research and development; incorporates an IAP ligand plus an amide-alkylC4 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T37618 Leukotriene B4 dimethyl amide

Leukotriene B4 dimethyl amide

Others Others
LTB4 dimethyl amide is a moderate inhibitor of LTB4-induced degranulation of human neutrophils (Ki = 130 nM) and lysozyme release from rat PMNL. LTB4 dimethyl amide appears to be an antagonist of the LTB4 receptor on guinea pig lung membranes.
T36278 VH 032 amide-alkylC3-acid

VH 032 amide-alkylC3-acid

Others Others
Functionalized von-Hippel-Lindau protein ligand (VHL) for research and development; incorporates an E3 ligase ligand plus alkylC3 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules.
T36277 VH 032 amide-alkylC2-acid

VH 032 amide-alkylC2-acid

Others Others
Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus alkylC2 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T38784 Histone H3 (1-25), amide

Histone H3 (1-25), amide

Histone H3 (1-25), amide is a N-terminal peptide fragment of histone H3 that serves as a substrate for histone methyltransferases (HMTs). It can be utilized to identify the substrate for HMTs. Compared to histone H3 (15-39) and full-length histone H3, Histone H3 (1-25), amide proves to be more efficient as a substrate for HMT G9a.
T36282 VH 032 amide-alkylC7-amine

VH 032 amide-alkylC7-amine

Others Others
Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36283 VH 032 amide-alkylC8-acid

VH 032 amide-alkylC8-acid

Others Others
Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus alkylC8 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36266 VH 032 amide-PEG3-amine

VH 032 amide-PEG3-amine

Others Others
Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 1 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T38756 Thiol-C10-amide-PEG8

Thiol-C10-amide-PEG8

Others Others
Thiol-C10-amide-PEG8 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T38999 Biotin-C4-amide-C5-NH2

Biotin-C4-amide-C5-NH2

Others; ADC Linker Antibody-drug Conjugate/ADC Related; Others
Biotin-C4-amide-C5-NH2 is a cleavable linker employed for the synthesis of antibody-drug conjugates (ADCs).
T84652 Prostaglandin F2α ethyl amide

Dinoprost ethyl amide

Others Others
Prostaglandin F2αethyl amide (PGF2α-NEt), a PGF2α analog featuring an N-ethyl amide modification at the C-1 carboxyl group, possesses ocular hypotensive activity similar to PG esters. Introduced as alternative prostaglandin ocular hypotensive prodrugs, PGF2α-NEt and other PG N-ethyl amides, contrary to claims of not converting to free acids in vivo, have been demonstrated by our laboratory studies to undergo conversion by bovine and human corneal tissue into the respective free acids at a rate o...
T7813 α-MSH

MSH, amide,CZEN-002,美拉诺坦,α-Melanocyte-Stimulating Hormone (MSH), amide

Melanocortin Receptor; Adenylyl cyclase GPCR/G Protein; Neuroscience
α-MSH (MSH, amide) 是一种内源性神经肽,是一种内源性黑皮质素受体 4 (MC4R) 激动剂,具有抗炎和解热活性。
T36280 VH 032 amide-alkylC4-acid

VH 032 amide-alkylC4-acid

Others Others
Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus alkylC4 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 5 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36285 VH 032 amide-PEG1-acid

VH 032 amide-PEG1-acid

Others Others
Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG1 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36267 VH 032 amide-PEG4-amine

VH 032 amide-PEG4-amine

Others Others
Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 2 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T39900 Thalidomide-O-amide-C5-NH2

Thalidomide-O-amide-C5-NH2

Others Others
Thalidomide-O-amide-C5-NH2 is a chemically synthesized conjugate, serving as an E3 ligase ligand-linker, which combines a cereblon ligand derived from Thalidomide with a linker that is commonly employed in PROTAC technology.

化合物

[Met5]-Enkephalin, amide TFA
Cat.No: TP1254
Synonym: 5-Methionine-enkephalin amide (TFA)
Target: Opioid Receptor
[Leu5]-Enkephalin, amide acetate
Cat.No: TP1113L
Synonym: [Leu5]-Enkephalin, amide acetate(60117-24-0 free base)
Target: Opioid Receptor
Acetyl-PHF6 amide acetate
Cat.No: TP1250L
Synonym: Acetyl-PHF6 amide acetate(878663-43-5 free base),AcPHF6 acetate,Ac-VQIVYK-NH2 acetate
Target: Others
2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base)
Cat.No: TP1378
Synonym: 2-Furoyl-LIGRLO-amide
Target: Protease-activated Receptor
PKI 14-22 amide, myristoylated Acetate
Cat.No: T21983L
Synonym: PKI 14-22 amide, myristoylated Acetate(201422-03-9 Free base)
Target: PKA
GLP-1(7-36), amide
Cat.No: T3984
Synonym: MKC 253,胰高血糖素样肽-1,Human GLP-1-(7-36)-amide,Glucagon-like Peptide 1 (7-36) amide,Glucagon-Like Peptide (GLP) I (7-36), amide, human,GLP-1(7-36),GLP-1-(7-36)-amide
Target: Glucagon Receptor
γ-1-MSH, amide acetate (72629-65-3 free base)
Cat.No: TP1002L
Synonym: γ-1-MSH, amide acetate
Target: Others
Angiotensin amide acetate
Cat.No: TP2446L
Synonym: 血管紧张素胺,Angiotensin amide acetate(53-73-6 Free base)
Target: Others
Phe-Met-Arg-Phe, amide acetate
Cat.No: TP1858L
Synonym: Phe-Met-Arg-Phe, amide acetate(64190-70-1 freebase)
Target: Potassium Channel
Diclofenac Amide
Cat.No: T0643
Synonym:
Target: Others
GLP-1(32-36)amide acetate
Cat.No: T37891L
Synonym: GLP-1(32-36)amide 醋酸盐,GLP-1(32-36)amide acetate(1417302-71-6 Free base)
Target: Others
TRAP-6 amide acetate
Cat.No: T38852L
Synonym:
Target: Protease-activated Receptor
PKA Inhibitor Fragment (6-22) amide TFA
Cat.No: T75888
Synonym: PKI-(6-22)-amide TFA,PKA Inhibitor Fragment (6-22) amide TFA(121932-06-7 Free base)
Target: PKA
GLP-1(28-36)amide acetate
Cat.No: T37890L
Synonym: GLP-1(28-36)amide acetate(1225021-13-5 Free base)
Target: Antioxidant, Glucagon Receptor
Nociceptin (1-13) amide TFA
Cat.No: TP1793L
Synonym:
Target: Opioid Receptor
PKA inhibitor fragment (6-22) amide Acetate
Cat.No: T21674L
Synonym: PKA inhibitor fragment (6-22) amide Acetate(121932-06-7 Free base)
Target: PKA
gamma-preprotachykinin amide (72-92) acetate
Cat.No: T9417L
Synonym: gamma-preprotachykinin amide (72-92) acetate (114882-65-4 Free base)
Target: Others
N-acetylcysteine amide
Cat.No: T5518
Synonym:
Target: Reactive Oxygen Species, ROS
N-Acetyl lysyltyrosylcysteine amide
Cat.No: T38063
Synonym:
Target: Glutathione Peroxidase
GIP (1-30) amide, porcine acetate
Cat.No: T37588L
Synonym:
Target: IGF-1R
GLP-1 (9-36) amide
Cat.No: TP2252
Synonym:
Target: Glucagon Receptor
Neuropeptide Y (29-64), amide, human acetate
Cat.No: TP1140L
Synonym:
Target: Neuropeptide Y Receptor
a-MSH, amide Acetate(581-05-5 free base)
Cat.No: TP2212L
Synonym:
Target: Melanocortin Receptor
PAR-4 Agonist Peptide, amide TFA
Cat.No: TP1065
Synonym: PAR-4-AP (TFA),AY-NH2 (TFA)
Target: Protease-activated Receptor
Biotin-PEG4-Amide-C6-Azide
Cat.No: T17580
Synonym: 生物素-四聚乙二醇-氨基-C6-叠氮
Target: Others, PROTAC Linker
Protease-Activated Receptor-2, amide
Cat.No: T7513
Synonym: 蛋白酶活化的受体-2,酰胺,SLIGKV-NH2,H-丝氨酰亮氨酰异亮氨酰甘氨酰赖氨酰缬氨酰NH2
Target: Protease-activated Receptor
Betulinic glycine amide
Cat.No: T85009
Synonym: Betulinic glycine amide
Target: Others
Labetalone hydrochloride
Cat.No: T35326
Synonym: Labetalone hydrochloride,Benzoic amide
Target: Others, Adrenergic Receptor
GW-Amide
Cat.No: T25474
Synonym: Glycyl-tryptophanamide,GW Amide
Target: Others
Amylin, amide, human
Cat.No: TP1183
Synonym: DAP amide, human
Target:
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate
Cat.No: T9691L
Synonym:
Target: Thyroid hormone receptor(THR)
[Met5]-Enkephalin, amide
Cat.No: TP1255
Synonym: 5-Methionine-enkephalin amide
Target:
A 410099.1 amide-PEG5-amine
Cat.No: T35473
Synonym: A 410099.1 amide-PEG5-amine
Target: Others
A 410099.1 amide-PEG3-amine
Cat.No: T35471
Synonym: A 410099.1 amide-PEG3-amine
Target: Others
A 410099.1 amide-alkylC4-amine
Cat.No: T35469
Synonym: A 410099.1 amide-alkylC4-amine
Target: Others
Leukotriene B4 dimethyl amide
Cat.No: T37618
Synonym: Leukotriene B4 dimethyl amide
Target: Others
VH 032 amide-alkylC3-acid
Cat.No: T36278
Synonym: VH 032 amide-alkylC3-acid
Target: Others
VH 032 amide-alkylC2-acid
Cat.No: T36277
Synonym: VH 032 amide-alkylC2-acid
Target: Others
Histone H3 (1-25), amide
Cat.No: T38784
Synonym: Histone H3 (1-25), amide
Target:
VH 032 amide-alkylC7-amine
Cat.No: T36282
Synonym: VH 032 amide-alkylC7-amine
Target: Others
VH 032 amide-alkylC8-acid
Cat.No: T36283
Synonym: VH 032 amide-alkylC8-acid
Target: Others
VH 032 amide-PEG3-amine
Cat.No: T36266
Synonym: VH 032 amide-PEG3-amine
Target: Others
Thiol-C10-amide-PEG8
Cat.No: T38756
Synonym: Thiol-C10-amide-PEG8
Target: Others
Biotin-C4-amide-C5-NH2
Cat.No: T38999
Synonym: Biotin-C4-amide-C5-NH2
Target: Others, ADC Linker
Prostaglandin F2α ethyl amide
Cat.No: T84652
Synonym: Dinoprost ethyl amide
Target: Others
α-MSH
Cat.No: T7813
Synonym: MSH, amide,CZEN-002,美拉诺坦,α-Melanocyte-Stimulating Hormone (MSH), amide
Target: Melanocortin Receptor, Adenylyl cyclase
VH 032 amide-alkylC4-acid
Cat.No: T36280
Synonym: VH 032 amide-alkylC4-acid
Target: Others
VH 032 amide-PEG1-acid
Cat.No: T36285
Synonym: VH 032 amide-PEG1-acid
Target: Others
VH 032 amide-PEG4-amine
Cat.No: T36267
Synonym: VH 032 amide-PEG4-amine
Target: Others
Thalidomide-O-amide-C5-NH2
Cat.No: T39900
Synonym: Thalidomide-O-amide-C5-NH2
Target: Others
Cat. No. Product Name Target Signaling Pathways
TP1232L Amylin, amide, rat acetate(124447-81-0,free base)

Amylin Receptor GPCR/G Protein
Amylin, amide, rat acetate(124447-81-0,free base) 是 AMY1 和 AMY3 受体以及 AMY2 受体的强效和高亲和力配体。
T13802 Oleamide

Oleic acid amide

Others; Endogenous Metabolite Metabolism; Others
Oleamide (Oleic acid amide) 是一种内源性脂肪酸酰胺,可用于哺乳动物神经系统的从头合成。
T7445 Acetamide

ethanamide,乙酰胺,Acetic acid amide

Endogenous Metabolite Metabolism
Acetamide (ethanamide) 是一种合成甲胺,是硫代乙酰胺和杀虫剂中间体。它可用作皮革、布料、涂料中的增塑剂。它具有致癌作用。
T22455 Vindesine sulfate

DVA,Desacetylvinblastine amide,硫酸长春地辛,DAVA,Desacetyl Vinblastine amide,VDS

Others Others
Vindesine sulfate (Desacetyl Vinblastine amide) 是一种长春花生物碱,它是长春碱的合成衍生物,与有丝分裂纺锤体的微管蛋白结合,导致微管结晶和有丝分裂停滞或细胞死亡。
T1426 Pyrazinamide

Pyrazinoic acid amide,Pyrazinecarboxamide,吡嗪酰胺

Antibacterial; Antibiotic; Autophagy; Fatty Acid Synthase Autophagy; Metabolism; Microbiology/Virology
Pyrazinamide (Pyrazinecarboxamide) 是一种口服抗结核类抗生素。它是一种前药,通过结核分枝杆菌pncA 基因编码的 PZase/烟酰胺酶转化为活性吡嗪酸形式。
T20091 Stearamide

Stearic acid amide,NSC 66462,NSC66462,NSC-66462

Stearamide(Stearic acid amide)是一种初级脂肪酸酰胺,具有细胞毒性和鱼类毒性,可用于增加纳米颗粒的性能。
T0326L L-Glutamine

L-Glutamic acid 5-amide,L-谷氨酰胺

Ferroptosis; Endogenous Metabolite; GluR Apoptosis; Metabolism; Neuroscience
L-Glutamine (L-Glutamic acid 5-amide) 是在人体中大量存在的一种非必需氨基酸,由谷氨酸和氨合成。它为某些细胞中的氧化提供了碳源。
T0934 Nicotinamide

Nicotinic acid amide,Vitamin B3,Niacinamide,烟酰胺,Vitamin PP

Sirtuin; Endogenous Metabolite Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
Nicotinamide 是维生素 B3 的吡啶核苷形式,可作为烟酰胺腺嘌呤二核苷酸或 NAD+ 的前体,可通过膳食摄入来补充,能预防或治疗黑舌病和糙皮病。
T39007 3,4-Dimethoxybenzamide

Others Others
3,4-Dimethoxybenzamide 是分离自Streptoverticillium morookaense 固体培养物的酰胺。它是制备盐酸伊托必利的起始原料。
TN2085 Piperlonguminine

Anti-infection; Antibacterial; Antifungal Microbiology/Virology
Piperlonguminine 是一种从 Piper 中分离出的生物碱酰胺。它具有多种生物活性,如神经保护、抗炎、抗肿瘤、抗血小板、抗黑素生成、抗真菌和抗菌活性。
TN1965 N-​Benzyllinolenamide

N-苄基-(9Z,12Z,15Z)-十八碳三烯酰胺,N-Benzyllinolenamide

FAAH; Autophagy Autophagy; Metabolism; Neuroscience
N-​Benzyllinolenamide 是从玛卡中得到的一种生物碱,是脂肪酰胺水解酶抑制剂,IC50 为 41.8 μM。
T2859 Biochanin A

4-Methylgenistein,鹰嘴豆芽素A,Olmelin

EGFR; FAAH; Autophagy Angiogenesis; Autophagy; JAK/STAT signaling; Metabolism; Neuroscience; Tyrosine Kinase/Adaptors
Biochanin A (4-Methylgenistein) 是一种从红三叶车轴草中分离出来的异黄酮衍生物,具有抗癌特性。它是脂肪酸酰胺水解酶抑制剂,作用于小鼠、大鼠和人 FAAH,IC50分别为 1.8、1.4 和 2.4 μM。
T12139 N-(3-Methoxybenzyl)Palmitamide

N-(3-甲氧基苄基)十六碳酰胺,玛卡酰胺杂质5

FAAH Metabolism; Neuroscience
N-(3-Methoxybenzyl)Palmitamide 是FAAH 抑制剂,可用于研究疼痛,炎症和中枢神经系统退行性疾病。
T3S2105 N-Benzylpalmitamide

Macamide 1,玛卡酰胺 B,N-苄基十六烷酰胺,N-Benzylhexadecanamide

Others; FAAH; Autophagy Autophagy; Metabolism; Neuroscience; Others
N-Benzylpalmitamide (Macamide 1) 是从玛卡中得到的一种生物碱,可以时间依赖性方式抑制脂肪酸酰胺水解酶,有治疗疼痛、炎症和中枢神经系统退行性疾病的研究潜力。
T4859 1-Monomyristin

rac-Glycerol 1-myristate,Glyceryl myristate,1-肉豆蔻酸单甘油酯,肉豆寇酸单甘油酯,Monomyristin,2,3-Dihydroxypropyl tetradecanoate

Others; FAAH; Endogenous Metabolite; Antibacterial; Autophagy; Antifungal Autophagy; Metabolism; Microbiology/Virology; Neuroscience; Others
1-Monomyristin (2,3-Dihydroxypropyl tetradecanoate) 是从 Serenoa repens 中提取的,抑制脂肪酸酰胺水解酶活性(IC50=18 μM) 和 2-油酰甘油的水解 (IC50=32 μM)。它对白色念珠菌有抗真菌活性,对金黄色葡萄球菌和聚集性放线菌有抗菌活性。
T1321 Nonivamide

Nonanoic acid vanillylamide,Pelargonic acid vanillylamide,辣椒素,Vanillyl-N-nonylamide,Pseudocapsaicin

TRP/TRPV Channel Membrane transporter/Ion channel
Nonivamide (Nonanoic acid vanillylamide) 具有激动活性,在静态毒性检测中,4d-EC50为 5.1 mg/L。
T6926 Palmitoylethanolamide

Mackpeart DR 14V,帕米醇,N-palmitoylethanolamine,Loramine P 256,Impulsin,AM 3112,Palmidrol

Influenza Virus; Endogenous Metabolite; PPAR DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
Palmitoylethanolamide (Impulsin) 是一种内源性脂肪酸酰胺。它有消炎药、降压药、神经保护剂和抗惊厥药的作用。在给药后,Palmitoylethanolamide 可抑制促炎介质从活化肥大细胞的释放。
TN4171 Grossamide

NO Synthase Immunology/Inflammation
Grossamide (GSE) 是一种来自虎杖的木脂酰胺。Grossamide 具有抗炎症活性,可通过上调精氨酸酶和下调诱导型一氧化氮合酶来抑制精氨酸产生一氧化氮(NO),抑制NO对OXPHOS的抑制作用。
T0769 Aceglutamide

N-乙酰-L-谷氨酰胺,N2-Acetylglutamine,α-N-Acetyl-L-glutamine,乙酰谷酰胺

Amino Acids and Derivatives; Endogenous Metabolite; Autophagy Autophagy; Metabolism
Aceglutamide (N2-Acetylglutamine) 是一种精神激活剂和促智剂,是氨基酸 L-谷氨酰胺的乙酰衍生物,用于改善记忆和集中注意力。
T32614 L-Clausenamide

(-)-Clausenamide

Microtubule Associated Cytoskeletal Signaling
L-Clausenamide 是从黄皮 (Clausena lansium (Lour) skeels) 的树叶中提取出来的生物碱,可用于提高认知功能。L-Clausenamide 对β-淀粉样蛋白 (Aβ) 毒性有抑制作用,通过抑制 tau 蛋白磷酸化阻止神经纤维缠结的形成。L-Clausenamide 具有神经保护活性,可用于调节 Aβ25-35 引发的刺激。L-Clausenamide 可用于研究阿尔兹海默症类的神经系统疾病。
T5222 N-(5-Aminopentyl)acetamide

Monoacetylcadaverine,N-(5-氨基戊基)乙酰胺,N-Acetylcadaverine,N-Acetyl-1,5-pentanediamine

Others; Endogenous Metabolite Metabolism; Others
N-(5-Aminopentyl)acetamide (N-Acetylcadaverine) 是用作多胺尸胺的乙酰化形式。尸胺是有机体中的氨基酸分解产生的,大剂量时有毒。
TN6794 N-(3-methoxybenzyl)-octadecanamide

Others Others
N-(3-methoxybenzyl)-octadecanamide 从玛卡 (Lepidium meyenii Walp.) 转化而来。
T13903 Stearoylethanolamide

N-(2-Hydroxyethyl)octadecanamide

Apoptosis Apoptosis
Stearoylethanolamide(N-(2-Hydroxyethyl)octadecanamide) 是一种存在于人、大鼠和小鼠大脑中的大麻素类化合物,具有促细胞凋亡活性。
T8150 Nudifloramide

1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide,1-甲基-6-氧代吡啶-3-甲酰胺

PARP; Endogenous Metabolite Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
Nudifloramide 是烟酰胺-腺嘌呤二核苷酸 (NAD) 降解的一种最终产物,可显著抑制PARP-1活性。
T4721 β-Nicotinamide mononucleotide

NMN,β-NM,β烟酰胺单核苷酸,烟酰胺单核苷酸

Others; Endogenous Metabolite Metabolism; Others
β-nicotinamide mononucleotide 是烟酰胺磷酸核糖转移酶 (NAMPT) 反应的产物。β-nicotinamide mononucleotide的作用包括其在细胞生化功能、心脏保护、糖尿病、肥胖相关并发症和阿尔茨海默病中的作用。
T14046 Anandamide

花生四烯酸乙醇胺,(5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide

Cannabinoid Receptor; Endogenous Metabolite GPCR/G Protein; Metabolism
Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide) 是一种免疫调节剂,通过大麻素受体 CB1 和 CB2 起作用,还通过中枢神经系统中的其他靶点起作用,如 GPR18/GPR55。
T14193 α-Galactosylceramide

KRN7000,α-GalCer

Others Others
α-Galactosylceramide (KRN7000) 是一种具有抗肿瘤和免疫刺激作用的合成糖脂。它是一种高效的 NKT 细胞激动剂,可与 CD1d 有效结合。它与 CD1d 的复合物可与 NKT 细胞的 T 细胞抗原受体结合。
TN1643 Ferulamide

4-Hydroxy-3-methoxycinnamide,阿魏酸酰胺

PAFR; AChR GPCR/G Protein; Neuroscience
Ferulamide (4-Hydroxy-3-methoxycinnamide) 是从巴豆中分离的阿魏酸衍生物,具有抗胆碱酯酶活性。
TN1457 Bryonamide B

Bryonamide B 是一种可从 Bryonia aspera 中提取得到一种葫芦类三萜。
T66582 6-Methylnicotinamide

Endogenous Metabolite Metabolism
6-Methylnicotinamide 是烟酰胺的衍生物,是一种内源性代谢物。在脑出血 (ICH) 急性期, 6-Methylnicotinamide 突然增加会加剧神经损伤。6-Methylnicotinamide 可用于制作共晶体/盐。
T13669 (E)-Cinnamamide

trans-Cinnamamide,肉桂酰胺

Others Others
(E)-Cinnamamide (trans-Cinnamamide) 是 Cinnamamide 的活性较低的异构体,Cinnamamide 是一种有效的非致命化学驱虫剂,适用于减少鸟类害虫的损害。
T0004 Salicylamide

水杨酰胺,Salamide,2-Hydroxybenzamide

COX Immunology/Inflammation; Neuroscience
Salicylamide(2-Hydroxybenzamide) 是一种止痛剂和抗热解药剂,是一种微粒体 UDP-葡糖醛酸基转移酶抑制剂。
TN1558 N-Vanillyldecanamide

癸酸香草酰胺,Decylic acid vanillylamide

Others Others
N-Vanillyldecanamide (Decylic acid vanillylamide) 分离自辣椒果实,以剂量依赖的方式显著减小紫花苜蓿幼苗的自由基长度。
TN7034 N-benzyl-heptadecanamide

N-Benzylheptadecanamide,N-苄基十七烷酰胺

Others Others
N-benzyl-heptadecanamide (N-Benzylheptadecanamide) 是玛咖中的一种玛卡酰胺。
TN7157 (+/-)-Longamide

Pyrrolo[1,2-a]pyrazin-1(2H)-one, 6,7-dibromo-3,4-dihydro-4-hydroxy-,6,7-dibromo-4-hydroxy-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one,6,7-dibromo-4-hydroxy-1H,2H,3H,4H-pyrrolo[1,2-a]pyrazin-1-one

Others Others
(+/-)-Longamide (6,7-dibromo-4-hydroxy-1H,2H,3H,4H-pyrrolo[1,2-a]pyrazin-1-one) 是一种海洋来源的天然产物,存在于Agelas flabelliformis。
TQ0131 Rocaglamide

Rocaglamide A,楝酰胺,Roc-A

HSP; NF-κB; PERK Apoptosis; Cytoskeletal Signaling; Metabolism; NF-κB
Rocaglamide (Roc-A) 是从米仔兰中分离出来的一种天然产物,具有抗癌特性,可用于咳嗽,受伤,哮喘和炎症性皮肤病。它是一种有效的选择性热休克因子 1 活化抑制剂,IC50约为 50 nM。它是 T 细胞中 NF-κB 活化的有效抑制剂,还抑制翻译起始因子eIF4A 的功能。
TN7061 yuanamide

Others Others
yuanamide 是一种天然化合物,属于生物碱类。
T26288 Clovamide

trans-Clovamide,N-trans-Caffeoy-L-dopa

Apoptosis; Influenza Virus; ROS; Antibacterial Apoptosis; Immunology/Inflammation; Microbiology/Virology
Clovamide (trans-Clovamide) 是一种天然存在的咖啡酰结合物,具有抗菌、抗炎、抗氧化和神经保护作用。它是一种极好的活性氧和氧自由基清除剂。
TN7036 N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide

(9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide,间-甲氧基苄基-亚麻酰胺,Macamide Impurity 14

Wnt/beta-catenin Cytoskeletal Signaling; Stem Cells
N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide (Macamide Impurity 14) 是一种从玛卡中分离得到的玛卡酰胺。它能够激活典型的Wnt/β‐catenin 信号通路,诱导间充质干细胞成骨分化和随后的骨形成,可用于研究骨质疏松症。
T1165 Ethionamide

Bayer 5312,乙硫异烟胺,2-ethylthioisonicotinamide,Ethinamide

Dehydrogenase; CAT; Antibacterial; Antibiotic Metabolism; Microbiology/Virology; oxidation-reduction
Ethionamide (2-ethylthioisonicotinamide) 是一种抗结核抗生素。
T6780 Benzamide

Amid kyseliny benzoove,苯甲酰胺,Phenylcarboxyamide,Benzoylamide

PARP; Endogenous Metabolite Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
Benzamide (Amid kyseliny benzoove) 是聚(ADP-核糖)聚合酶的抑制剂,是苯甲酸的衍生物。
TN7126 N-Vanillyloctanamide

Others Others
N-Vanillyloctanamide 是一种来自 Capsicum annuum L. var. 果实的辣椒素。年鉴。 N-Vanillyloctanamide 减少 Lactuca sativa 幼苗的自由基长度,这种抑制是剂量依赖性的。
TJS2216 Aurantiamide acetate

金色酰胺醇酯,Asperglaucide

Cysteine Protease Proteases/Proteasome
Aurantiamide acetate (Asperglaucide) 是抑制口服有活性的 cathepsin 选择性抑制剂,分离自 Portulaca oleracea L。它具有抗炎作用,可用于研究炎性相关疾病。
T5704 Entadamide-A-β-D-glucopyranoside

(E)-N-[2-(β-D-Glucopyranosyloxy)ethyl]-,榼藤子酰胺A-Β-D-吡喃葡萄糖苷,榼藤子酰胺A-β-D-吡喃葡萄糖

Others Others
Entadamide-A-β-D-glucopyranoside ((E)-N-[2-(β-D-Glucopyranosyloxy)ethyl]-) 是一种菜豆虫种子的主要成分,具有抗补体作用。
T5233 N-Methylnicotinamide

N'-Methylnicotinamide,Nicotinic Acid Methylamide,N-Methylpyridine-3-carboxamide,N-甲基烟酰胺

Others; Endogenous Metabolite Metabolism; Others
N-Methylnicotinamide 是内源性代谢产物的一种,可改善内皮功能障碍。
T13795 Nicotinamide riboside

Sirtuin Chromatin/Epigenetic; DNA Damage/DNA Repair
Nicotinamide riboside 是维生素 B3 的来源,可以增强氧化代谢并防止高脂肪饮食诱导的代谢异常。它是具有口服活性的 NAD+的前体,增加 NAD+水平并激活SIRT1和SIRT3,可用于研究阿尔茨海默氏病的认知退化。
T6220 Nicotinamide riboside chloride

烟酰胺核糖氯酸盐,烟酰胺核苷

Sirtuin; Endogenous Metabolite Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
Nicotinamide riboside Chloride 是维生素 B3 的来源,可以增强氧化代谢并防止高脂肪饮食诱导的代谢异常。它是具有口服活性的 NAD+的前体,增加 NAD+水平并激活SIRT1和SIRT3,可用于研究阿尔茨海默氏病的认知退化。
TN7158 2-(4-methoxyphenyl)-N-methyl-2-oxoacetamide

N-Methyl-2-(4-methoxyphenyl)-2-oxoacetamide,2-(4-methoxy-phenyl)-N-methyl-2-oxo-acetamide

Others Others
2-(4-methoxyphenyl)-N-methyl-2-oxoacetamide (2-(4-methoxy-phenyl)-N-methyl-2-oxo-acetamide) 是一种海洋来源的天然产物,存在于Polycarpa aurata。
TN2239 Strictosamide

异长春花苷内酰胺

ATPase; Potassium Channel; Sodium Channel; Parasite; Antifungal Membrane transporter/Ion channel; Microbiology/Virology
Strictosamide 具有抗炎、抗疟原虫和抗真菌活性。
T22644 C2 Ceramide

Ceramide

Others Others
A potent modulator of cell proliferation and differentiation.
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天然产物

Amylin, amide, rat acetate(124447-81-0,free base)
Cat.No: TP1232L
Synonym:
Target: Amylin Receptor
Oleamide
Cat.No: T13802
Synonym: Oleic acid amide
Target: Others, Endogenous Metabolite
Acetamide
Cat.No: T7445
Synonym: ethanamide,乙酰胺,Acetic acid amide
Target: Endogenous Metabolite
Vindesine sulfate
Cat.No: T22455
Synonym: DVA,Desacetylvinblastine amide,硫酸长春地辛,DAVA,Desacetyl Vinblastine amide,VDS
Target: Others
Pyrazinamide
Cat.No: T1426
Synonym: Pyrazinoic acid amide,Pyrazinecarboxamide,吡嗪酰胺
Target: Antibacterial, Antibiotic, Autophagy, Fatty Acid Synthase
Stearamide
Cat.No: T20091
Synonym: Stearic acid amide,NSC 66462,NSC66462,NSC-66462
Target:
L-Glutamine
Cat.No: T0326L
Synonym: L-Glutamic acid 5-amide,L-谷氨酰胺
Target: Ferroptosis, Endogenous Metabolite, GluR
Nicotinamide
Cat.No: T0934
Synonym: Nicotinic acid amide,Vitamin B3,Niacinamide,烟酰胺,Vitamin PP
Target: Sirtuin, Endogenous Metabolite
3,4-Dimethoxybenzamide
Cat.No: T39007
Synonym:
Target: Others
Piperlonguminine
Cat.No: TN2085
Synonym:
Target: Anti-infection, Antibacterial, Antifungal
N-​Benzyllinolenamide
Cat.No: TN1965
Synonym: N-苄基-(9Z,12Z,15Z)-十八碳三烯酰胺,N-Benzyllinolenamide
Target: FAAH, Autophagy
Biochanin A
Cat.No: T2859
Synonym: 4-Methylgenistein,鹰嘴豆芽素A,Olmelin
Target: EGFR, FAAH, Autophagy
N-(3-Methoxybenzyl)Palmitamide
Cat.No: T12139
Synonym: N-(3-甲氧基苄基)十六碳酰胺,玛卡酰胺杂质5
Target: FAAH
N-Benzylpalmitamide
Cat.No: T3S2105
Synonym: Macamide 1,玛卡酰胺 B,N-苄基十六烷酰胺,N-Benzylhexadecanamide
Target: Others, FAAH, Autophagy
1-Monomyristin
Cat.No: T4859
Synonym: rac-Glycerol 1-myristate,Glyceryl myristate,1-肉豆蔻酸单甘油酯,肉豆寇酸单甘油酯,Monomyristin,2,3-Dihydroxypropyl tetradecanoate
Target: Others, FAAH, Endogenous Metabolite, Antibacterial, Autophagy, Antifungal
Nonivamide
Cat.No: T1321
Synonym: Nonanoic acid vanillylamide,Pelargonic acid vanillylamide,辣椒素,Vanillyl-N-nonylamide,Pseudocapsaicin
Target: TRP/TRPV Channel
Palmitoylethanolamide
Cat.No: T6926
Synonym: Mackpeart DR 14V,帕米醇,N-palmitoylethanolamine,Loramine P 256,Impulsin,AM 3112,Palmidrol
Target: Influenza Virus, Endogenous Metabolite, PPAR
Grossamide
Cat.No: TN4171
Synonym:
Target: NO Synthase
Aceglutamide
Cat.No: T0769
Synonym: N-乙酰-L-谷氨酰胺,N2-Acetylglutamine,α-N-Acetyl-L-glutamine,乙酰谷酰胺
Target: Amino Acids and Derivatives, Endogenous Metabolite, Autophagy
L-Clausenamide
Cat.No: T32614
Synonym: (-)-Clausenamide
Target: Microtubule Associated
N-(5-Aminopentyl)acetamide
Cat.No: T5222
Synonym: Monoacetylcadaverine,N-(5-氨基戊基)乙酰胺,N-Acetylcadaverine,N-Acetyl-1,5-pentanediamine
Target: Others, Endogenous Metabolite
N-(3-methoxybenzyl)-octadecanamide
Cat.No: TN6794
Synonym:
Target: Others
Stearoylethanolamide
Cat.No: T13903
Synonym: N-(2-Hydroxyethyl)octadecanamide
Target: Apoptosis
Nudifloramide
Cat.No: T8150
Synonym: 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide,1-甲基-6-氧代吡啶-3-甲酰胺
Target: PARP, Endogenous Metabolite
β-Nicotinamide mononucleotide
Cat.No: T4721
Synonym: NMN,β-NM,β烟酰胺单核苷酸,烟酰胺单核苷酸
Target: Others, Endogenous Metabolite
Anandamide
Cat.No: T14046
Synonym: 花生四烯酸乙醇胺,(5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide
Target: Cannabinoid Receptor, Endogenous Metabolite
α-Galactosylceramide
Cat.No: T14193
Synonym: KRN7000,α-GalCer
Target: Others
Ferulamide
Cat.No: TN1643
Synonym: 4-Hydroxy-3-methoxycinnamide,阿魏酸酰胺
Target: PAFR, AChR
Bryonamide B
Cat.No: TN1457
Synonym:
Target:
6-Methylnicotinamide
Cat.No: T66582
Synonym:
Target: Endogenous Metabolite
(E)-Cinnamamide
Cat.No: T13669
Synonym: trans-Cinnamamide,肉桂酰胺
Target: Others
Salicylamide
Cat.No: T0004
Synonym: 水杨酰胺,Salamide,2-Hydroxybenzamide
Target: COX
N-Vanillyldecanamide
Cat.No: TN1558
Synonym: 癸酸香草酰胺,Decylic acid vanillylamide
Target: Others
N-benzyl-heptadecanamide
Cat.No: TN7034
Synonym: N-Benzylheptadecanamide,N-苄基十七烷酰胺
Target: Others
(+/-)-Longamide
Cat.No: TN7157
Synonym: Pyrrolo[1,2-a]pyrazin-1(2H)-one, 6,7-dibromo-3,4-dihydro-4-hydroxy-,6,7-dibromo-4-hydroxy-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one,6,7-dibromo-4-hydroxy-1H,2H,3H,4H-pyrrolo[1,2-a]pyrazin-1-one
Target: Others
Rocaglamide
Cat.No: TQ0131
Synonym: Rocaglamide A,楝酰胺,Roc-A
Target: HSP, NF-κB, PERK
yuanamide
Cat.No: TN7061
Synonym:
Target: Others
Clovamide
Cat.No: T26288
Synonym: trans-Clovamide,N-trans-Caffeoy-L-dopa
Target: Apoptosis, Influenza Virus, ROS, Antibacterial
N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide
Cat.No: TN7036
Synonym: (9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide,间-甲氧基苄基-亚麻酰胺,Macamide Impurity 14
Target: Wnt/beta-catenin
Ethionamide
Cat.No: T1165
Synonym: Bayer 5312,乙硫异烟胺,2-ethylthioisonicotinamide,Ethinamide
Target: Dehydrogenase, CAT, Antibacterial, Antibiotic
Benzamide
Cat.No: T6780
Synonym: Amid kyseliny benzoove,苯甲酰胺,Phenylcarboxyamide,Benzoylamide
Target: PARP, Endogenous Metabolite
N-Vanillyloctanamide
Cat.No: TN7126
Synonym:
Target: Others
Aurantiamide acetate
Cat.No: TJS2216
Synonym: 金色酰胺醇酯,Asperglaucide
Target: Cysteine Protease
Entadamide-A-β-D-glucopyranoside
Cat.No: T5704
Synonym: (E)-N-[2-(β-D-Glucopyranosyloxy)ethyl]-,榼藤子酰胺A-Β-D-吡喃葡萄糖苷,榼藤子酰胺A-β-D-吡喃葡萄糖
Target: Others
N-Methylnicotinamide
Cat.No: T5233
Synonym: N'-Methylnicotinamide,Nicotinic Acid Methylamide,N-Methylpyridine-3-carboxamide,N-甲基烟酰胺
Target: Others, Endogenous Metabolite
Nicotinamide riboside
Cat.No: T13795
Synonym:
Target: Sirtuin
Nicotinamide riboside chloride
Cat.No: T6220
Synonym: 烟酰胺核糖氯酸盐,烟酰胺核苷
Target: Sirtuin, Endogenous Metabolite
2-(4-methoxyphenyl)-N-methyl-2-oxoacetamide
Cat.No: TN7158
Synonym: N-Methyl-2-(4-methoxyphenyl)-2-oxoacetamide,2-(4-methoxy-phenyl)-N-methyl-2-oxo-acetamide
Target: Others
Strictosamide
Cat.No: TN2239
Synonym: 异长春花苷内酰胺
Target: ATPase, Potassium Channel, Sodium Channel, Parasite, Antifungal
C2 Ceramide
Cat.No: T22644
Synonym: Ceramide
Target: Others
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Cat. No. Product Name Species Expression System
TMPH-01325 FAAH2 Protein, Human, Recombinant (His)

Amidase domain-containing protein,Anandamide amidoh...

Human E. coli
Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatty amides, to their corresponding fatty acids, thereby regulating the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates. FAAH2 Protein, Human, Recombinant (His) is expressed in E. coli e...
TMPH-02561 CES1C Protein, Mouse, Recombinant (GST)

Liver carboxylesterase N,Es1,Lung surfactant convertase,Carb...

Mouse E. coli
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant.
TMPH-02563 CES1C Protein, Mouse, Recombinant

Es1,PES-N,Liver carboxylesterase N,Carboxylesterase 1C,Lung ...

Mouse E. coli
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant. CES1C Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 58.6 kDa and the accession number is P23953.
TMPH-02562 CES1C Protein, Mouse, Recombinant (His & Myc)

Ces1c,Liver carboxylesterase N,Es1,Lung surfactant convertas...

Mouse HEK293 Cells
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant.
TMPY-01189 GFPT1 Protein, Human, Recombinant

GFAT1,CMSTA1,GFAT,glutamine--fructose-6-phosphate transamina...

Human E. coli
Glutamine:fructose-6-phosphate amidotransferase 1 (GFAT), also known as GFPT1, is a member of the N-terminal nucleophile aminotransferases and the first rate-limiting enzyme for the entry of glucose into the hexosamine biosynthesis pathway (HBP) in mammals. GFAT transfers the amino group from the L-glutamine amide to the D-fructose 6-phosphate, producing glutamic acid and glucosamine 6-phosphate. GFAT exists as a homotetramer in cytoplasm, and is proposed to be most likely involved in re...
TMPH-03260 Carboxypeptidase A1 Protein, Rat, Recombinant (His & Myc)

Cpa1,Carboxypeptidase A1,Cpa

Rat E. coli
Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro. Catalyzes the conversion of leukotriene C4 to leukotriene F4 via the hydrolysis of an amide bond. Carboxypeptidase A1 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.6 kDa and the accession number is P00731.
TMPH-02778 Mcpt4 Protein, Mouse, Recombinant (E. coli, His)

MSMCP,Mast cell protease 4,Myonase,Serosal mast cell proteas...

Mouse E. coli
Has chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4-|-Ile-5' bond of angiotensin I and the 'Phe-20-|-Ala-21' bond of amyloid beta-protein, and is less active towards the 'Phe-8-|-His-9' bond of angiotensin I and the 'Phe-4-|-Ala-5' and 'Tyr-10-|-Glu-11' bonds of amyloid beta-protein. Involved in thrombin regulation and fibronectin processing. Mcpt4 Protein, Mouse, Recombinant (E. c...
TMPJ-00474 CPA1 Protein, Human, Recombinant (His)

CPA,Carboxypeptidase A1,CPA1

Human HEK293 Cells
Carboxypeptidase A1 (CPA1) is secreted as a pancreatic peptidase that comes from the precursor form of inactive procarboxypeptidase. CPA1 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. It has a free C-terminal carboxyl group, with the preference of residues with aromatic or branched aliphatic side chains. CPA1 cleaves the C-terminal amide or ester bond of peptides and involves in zymogen inhibition. Three different forms of hu...
TMPJ-00602 CPA2 Protein, Human, Recombinant (His)

CPA2,Carboxypeptidase A2

Human HEK293 Cells
Carboxypeptidase A2 (CPA) is a secreted pancreatic procarboxy-peptidase that cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group. The hydrolytic action of CPA2 was identified with a preference towards long substrates with aromatic amino acids in their C-terminal end, particularly tryptophan. CPA2 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. Three different forms of human pancreat...

重组蛋白

FAAH2 Protein, Human, Recombinant (His)
Cat.No: TMPH-01325
Species: Human
Expression System: E. coli
CES1C Protein, Mouse, Recombinant (GST)
Cat.No: TMPH-02561
Species: Mouse
Expression System: E. coli
CES1C Protein, Mouse, Recombinant
Cat.No: TMPH-02563
Species: Mouse
Expression System: E. coli
CES1C Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02562
Species: Mouse
Expression System: HEK293 Cells
GFPT1 Protein, Human, Recombinant
Cat.No: TMPY-01189
Species: Human
Expression System: E. coli
Carboxypeptidase A1 Protein, Rat, Recombinant (His & Myc)
Cat.No: TMPH-03260
Species: Rat
Expression System: E. coli
Mcpt4 Protein, Mouse, Recombinant (E. coli, His)
Cat.No: TMPH-02778
Species: Mouse
Expression System: E. coli
CPA1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00474
Species: Human
Expression System: HEK293 Cells
CPA2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00602
Species: Human
Expression System: HEK293 Cells
Cat. No. Product Name Target Signaling Pathways
T69395 Nicotinamide-d4

Nicotinamide-d4 is intended for use as an internal standard for the quantification of nicotinamide by GC- or LC-MS. Nicotinamide is an amide form of niacin, which is also known as vitamin B3, that can be biosynthesized in vivo or obtained through the diet. It is a precursor in the synthesis of the metabolic cofactor NAD+ and an inhibitor of sirtuin 1 (SIRT1; IC50 = <50 µM). Nicotinamide (10 µM) increases the activity of serine palmitoyltransferase (SPT) and the biosynthesis of ceramide, glucosyl...
TMIJ-0310 Pyrazinamide-d3

Pyrazinamide-d3 是 Pyrazinamide 的氘代化合物。Pyrazinamide 的 CAS 号为 98-96-4。Pyrazinamide是一种口服抗结核类抗生素。它是一种前药,通过结核分枝杆菌pncA基因编码的 PZase/烟酰胺酶转化为活性吡嗪酸形式。
T11208 Enzalutamide-d3

MDV3100 D3

Others Others
Enzalutamide D3 is a deuterium labeled Enzalutamide . Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells.
T70186 Methazolamide-d6

Methazolamide-d6 is intended for use as an internal standard for the quantification of methazolamide by GC- or LC-MS. Methazolamide is a carbonic anhydrase inhibitor. It reduces intraocular pressure and cerebrospinal fluid flow in a rat model of glaucoma. Methazolamide reduces electroshock-induced seizures in rats with an ED50 value of 19.2 mg/kg. It also inhibits production of reactive oxygen species (ROS) in a primary cortical neuron (PCN) cellular model of subarachnoid hemorrhage (SAH) and re...
TMIJ-0240 Lacosamide-d3 (Acetyl-d3)

Lacosamide-d3 (Acetyl-d3) 是 Lacosamide 的氘代化合物。Lacosamide 的 CAS 号为 175481-36-4。Lacosamide是一种功能化氨基酸。Lacosamide以一种新的方式调节钠通道:它选择性地增强钠通道缓慢失活,而对快速失活没有影响Lacosamine在不同的啮齿类动物癫痫发作模型中显示出抗癫痫作用,在反映神经性疼痛和慢性炎性疼痛的不同类型和症状的实验动物模型中显示了抗伤害潜力。
TMID-0204 Cyclophosphamide-d4

Cyclophosphamide-d4 是 Cyclophosphamide 的氘代化合物。Cyclophosphamide 的 CAS 号为 50-18-0。Cyclophosphamide 是一种烷化剂,具有抗肿瘤及免疫抑制活性,用于治疗多种癌症。
TMIJ-0278 4,6-Dichloro-N-(methyl-d3)-3-pyridazinecarboxamide

4,6-Dichloro-N-(methyl-d3)-3-pyridazinecarboxamide 是 4,6-Dichloro-N-(methyl)-3-pyridazinecarboxamide 的氘代化合物。4,6-Dichloro-N-(methyl)-3-pyridazinecarboxamide 的 CAS 号为 1609394-78-6。
TMIJ-0391 Acrylamide-2,3,3-d3

Acrylamide-2,3,3-d3 是 Acrylamide 的氘代化合物。Acrylamide 的 CAS 号为 79-06-1。Acrylamide monomer 是丙烯酰胺类的成员。它具有致癌剂、神经毒素、诱变剂、烷化剂和美拉德反应产物的作用。
T69758 Flutamide-d7

Flutamide-d7 is intended for use as an internal standard for the quantification of flutamide by GC- or LC-MS. Flutamide is an androgen receptor antagonist and prodrug form of 2-hydroxy flutamide. Flutamide is converted to 2-hydroxy flutamide by the cytochrome P450 (CYP) isoform CYP1A2 in human liver microsomes. It is cytotoxic to PC3 and LNCaP prostate cancer cells with IC50 values of 98.8 and 81.8 µM, respectively. Flutamide (50 mg/kg per day) reduces tumor growth in a PC-82 mouse xenograft mo...
T36059 Dichlorphenamide-13C6

Dichlorphenamide-13C6

Dichlorphenamide-13C6is intended for use as an internal standard for the quantification of dichlorphenamide by GC- or LC-MS. Dichlorphenamide is a sulfonamide and an orally bioavailable carbonic anhydrase (CA) inhibitor (Kis = 1.20, 38, 50, and 50 nM for the human CA isoforms CAI, CAII, CAIX, and CAXII, respectively).1It lowers intraocular pressure in rabbits when 50 μl of a 10% solution is applied topically to the eye.2Dichlorphenamide rescues the potassium deficiency and prevents insulin-induc...
T10231 Acetazolamide-d3

醋氮酰胺 D3

Others Others
Acetazolamide D3 is a deuterium-labeled Acetazolamide. Acetazolamide is a potent carbonic anhydrase inhibitor.
TMIH-0307 Loperamide-d6

Loperamide-d6 是 Loperamide 的氘代化合物。Loperamide 的 CAS 号为 53179-11-6。
T19449 N-desmethyl Enzalutamide D6

N-desmethyl MDV 3100 D6

Androgen Receptor Endocrinology/Hormones
N-desmethyl Enzalutamide D6 is a deuterium labeled N-desmethyl Enzalutamide.
TMIH-0093 Apalutamide-d4

Apalutamide-d4 是 Apalutamide 的氘代化合物。
TMIH-0134 C24:1 Ceramide-d7

C24:1 Ceramide-d7 是 C24:1 Ceramide 的氘代化合物。
TMIH-0176 Darolutamide-d4

Darolutamide-d4 是 Darolutamide 的氘代化合物。
TMIH-0131 C16 Ceramide-d7

C16 Ceramide-d7 是 C16 Ceramide 的氘代化合物。
TMID-0299 Zonisamide-d4

Zonisamide-d4 是 Zonisamide 的氘代化合物。Zonisamide 的 CAS 号为 68291-97-4。Zonisamide 是锌酶碳酸酐酶 (carbonic anhydrase) 的有效抑制剂,对人类线粒体同工酶 hCA II 和 hCA V 作用的Ki值分别为 35.2 nM 和 20.6 nM。Zonisamide 具有抗癫痫活性,在癫痫、癫痫发作和帕金森病的研究中具有价值。
TMID-0192 Procainamide-d10

Procainamide-d10 是 Procainamide 的氘代化合物。Procainamide 的 CAS 号为 51-06-9。Procainamide 是一种特异性强效的 DNA 甲基转移酶 1 (DNMT1) 抑制剂。普鲁卡因胺是一种 1A 类抗心律失常药物。Procainamide 具有研究癌症和心律失常的潜力。
T11867 Loperamide-d6 hydrochloride

R-18553 D6 hydrochloride

Others Others
Loperamide D6 hydrochloride, a deuterium-labeled variant of Loperamide hydrochloride, acts as an opioid receptor agonist utilized for diarrhea treatment.
T13204 Trimethobenzamide D6

Others Others
Trimethobenzamide D6 is deuterium labeled Trimethobenzamide. Trimethobenzamide is a the D2 receptor blocker. Trimethobenzamide is an antiemetic.
TMID-0247 LacosaMide-d3

LacosaMide-d3 是 LacosaMide 的氘代化合物。LacosaMide 的 CAS 号为 175481-36-4。Lacosamide是一种功能化氨基酸。Lacosamide以一种新的方式调节钠通道:它选择性地增强钠通道缓慢失活,而对快速失活没有影响Lacosamine在不同的啮齿类动物癫痫发作模型中显示出抗癫痫作用,在反映神经性疼痛和慢性炎性疼痛的不同类型和症状的实验动物模型中显示了抗伤害潜力。
TMID-0066 rac-Lacosamide-d6

rac-Lacosamide-d6 是 rac-Lacosamide 的氘代化合物。rac-Lacosamide 的 CAS 号为 175481-36-4。
TMIJ-0390 N,N-Dimethylformamide-d7

N,N-Dimethylformamide-d7 是 N,N-Dimethylformamide 的氘代化合物。N,N-Dimethylformamide 的 CAS 号为 68-12-2。
TMIH-0034 2-Ethyl-2-phenylmalonamide-d5

2-Ethyl-2-phenylmalonamide-d5 是 2-Ethyl-2-phenylmalonamide 的氘代化合物。
TMIH-0132 C18 Ceramide-d7

C18 Ceramide-d7 是 C18 Ceramide 的氘代化合物。
TMIH-0092 Apalutamide-13C-d3

Apalutamide-13C-d3 是 Apalutamide 的 13C 和氘代化合物。Apalutamide 的 CAS 号为 956104-40-8。Apalutamide 是一种有效、竞争性的雄激素受体 (AR) 拮抗剂(IC50:16 nM)。
TMIH-0133 C24 Ceramide-d7

C24 Ceramide-d7 是 C24 Ceramide 的氘代化合物。
TMIJ-0264 Cyclophosphamide-d8

Cyclophosphamide-d8 是 Cyclophosphamide 的氘代化合物。Cyclophosphamide 的 CAS 号为 50-18-0。Cyclophosphamide 是一种烷化剂,具有抗肿瘤及免疫抑制活性,用于治疗多种癌症。
T19311 Enzalutamide carboxylic acid D6

MDV3100 carboxylic acid D6

Others Others
Enzalutamide carboxylic acid is an inactive metabolite of Enzalutamide. Enzalutamide carboxylic acid D6 is the deuterium labeled Enzalutamide carboxylic acid (MDV3100 carboxylic acid).
T37847 Zonisamide-13C2,15N

Zonisamide-13C2,15N

Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels (IC50 = 2 μg/ml) in mouse embryo spinal cord neurons and inhibits spontaneous channel firing when used at concentrations greater than 10 μg/ml.2 In rat cerebral cortex neurons, zonisamide (1-1,000 μM) inhibits T-type calcium channels with a maximum reduction of 60% of the calcium...
T40394 Benzamide-15N

Phenylamide-15N,Benzenecarboxamide-15N,NSC-3114-15N,Benzamide-15N

Benzamide-15N (NSC-3114-15N) is a 15N-labeled Benzamide. Benzamide inhibits poly(ADP-ribose) polymerase (PARP).
TMIH-0620 Arachidonoyl Ethanolamide-d4

AEA-d4

Deuterated anandamide, a synthetically modified version of anandamide where hydrogen atoms are replaced with deuterium (D), exhibits enhanced stability against oxidative degradation. This modification conserves the compound's pharmacological properties while prolonging its shelf life and efficacy in research applications, particularly in analytical and biochemical studies to elucidate the complex mechanisms of the endocannabinoid system.
TMIH-0372 N-desmethyl Apalutamide-d4

N-desmethyl Apalutamide-d4 是 N-desmethyl Apalutamide 的氘代化合物。N-desmethyl Apalutamide 的 CAS 号为 1332391-11-3。N-Desmethyl Apalutamide 是一种 Apalutamide 的活性代谢产物,主要由 CYP2C8 和 CYP3A4 介导形成。它是一种低活性的雄激素受体拮抗剂,其作用力是 Apalutamide 活性的三分之一。它是中等至强的CYP3A4和CYP2B6诱导剂,并具有优异的血浆蛋白结合浓度。
TMIH-0094 Apalutamide-d7

Apalutamide-d7 是 Apalutamide 的氘代化合物。Apalutamide 的 CAS 号为 956104-40-8。Apalutamide 是一种有效、竞争性的雄激素受体 (AR) 拮抗剂(IC50:16 nM)。
TMIH-0053 4-amino-N-(4-nitrophenyl)benzenesulfonamide-d4

4-amino-N-(4-nitrophenyl)benzenesulfonamide-d4 是 4-amino-N-(4-nitrophenyl)benzenesulfonamide 的氘代化合物。
TMIH-0035 2-Furamide-3,4,5-d3

2-Furamide-3,4,5-d3 是 2-Furamide-3,4,5 的氘代化合物。
TMIH-0218 Enzalutamide-d6 Carboxylic Acid

Enzalutamide-d6 Carboxylic Acid 是 Enzalutamide Carboxylic Acid 的氘代化合物。Enzalutamide Carboxylic Acid 的 CAS 号为 1242137-15-0。Enzalutamide carboxylic acid 是 Enzalutamide 非活性代谢物。Enzalutamide 是雄激素受体 (AR) 拮抗剂。
TMID-0185 (±)-Ropivacaine-d7

(±)-Ropivacaine-d7 是 (±)-Ropivacaine 的氘代化合物。(±)-Ropivacaine 的 CAS 号为 84057-95-4。Ropivacaine 是有效的钠通道阻断剂,通过可逆地抑制钠离子内流从而引起神经纤维脉冲传导阻滞。Ropivacaine 也是一种 K2P(双孔钾通道)TREK-1的抑制剂,在 COS-7 细胞膜上的 IC50值为 402.7 μM。Ropivacaine 可以用于神经性疼痛的缓解的相关研究。
TMIJ-0102 Ropivacaine-d7

Ropivacaine-d7 是 Ropivacaine 的氘代化合物。Ropivacaine 的 CAS 号为 84057-95-4。Ropivacaine 是有效的钠通道阻断剂,通过可逆地抑制钠离子内流从而引起神经纤维脉冲传导阻滞。Ropivacaine 也是一种 K2P(双孔钾通道)TREK-1的抑制剂,在 COS-7 细胞膜上的 IC50值为 402.7 μM。Ropivacaine 可以用于神经性疼痛的缓解的相关研究。
TMID-0262 Lidocaine-d10 (N,N-diethyl-d10)

Lidocaine-d10 (N,N-diethyl-d10) 是 Lidocaine 的氘代化合物。Lidocaine 的 CAS 号为 137-58-6。Lidocaine是一种酰胺衍生物,抑制涉及复杂电压和依赖性的钠通道,可用于研究室性心律失常。它通过调节 miR-145 表达和进一步抑制MEK/ERK和NF-κB信号通路来减少胃癌细胞的生长,迁移和侵袭。
T70882 Orlistat-d3

Orlistat-d3 is intended for use as an internal standard for the quantification of orlistat by GC- or LC-MS. Orlistat is a digestive lipase inhibitor. It inhibits diacylglycerol lipase α (DAGLα), DAGLβ, α/β-hydrolase domain-containing protein 12 (ABHD12), ABHD16A, and platelet-activating factor acetylhydrolase (PAF-AH; IC50s = 0.06, 0.1, 0.08, 0.03, and 0.05 µM, respectively), as well as pancreatic lipase and hormone-sensitive lipase (IC50s = 0.65 and 2.1 µg/ml, respectively) but does not inhibit...

同位素标记化合物

Nicotinamide-d4
Cat.No: T69395
Synonym:
Target:
Pyrazinamide-d3
Cat.No: TMIJ-0310
Synonym:
Target:
Enzalutamide-d3
Cat.No: T11208
Synonym: MDV3100 D3
Target: Others
Methazolamide-d6
Cat.No: T70186
Synonym:
Target:
Lacosamide-d3 (Acetyl-d3)
Cat.No: TMIJ-0240
Synonym:
Target:
Cyclophosphamide-d4
Cat.No: TMID-0204
Synonym:
Target:
4,6-Dichloro-N-(methyl-d3)-3-pyridazinecarboxamide
Cat.No: TMIJ-0278
Synonym:
Target:
Acrylamide-2,3,3-d3
Cat.No: TMIJ-0391
Synonym:
Target:
Flutamide-d7
Cat.No: T69758
Synonym:
Target:
Dichlorphenamide-13C6
Cat.No: T36059
Synonym: Dichlorphenamide-13C6
Target:
Acetazolamide-d3
Cat.No: T10231
Synonym: 醋氮酰胺 D3
Target: Others
Loperamide-d6
Cat.No: TMIH-0307
Synonym:
Target:
N-desmethyl Enzalutamide D6
Cat.No: T19449
Synonym: N-desmethyl MDV 3100 D6
Target: Androgen Receptor
Apalutamide-d4
Cat.No: TMIH-0093
Synonym:
Target:
C24:1 Ceramide-d7
Cat.No: TMIH-0134
Synonym:
Target:
Darolutamide-d4
Cat.No: TMIH-0176
Synonym:
Target:
C16 Ceramide-d7
Cat.No: TMIH-0131
Synonym:
Target:
Zonisamide-d4
Cat.No: TMID-0299
Synonym:
Target:
Procainamide-d10
Cat.No: TMID-0192
Synonym:
Target:
Loperamide-d6 hydrochloride
Cat.No: T11867
Synonym: R-18553 D6 hydrochloride
Target: Others
Trimethobenzamide D6
Cat.No: T13204
Synonym:
Target: Others
LacosaMide-d3
Cat.No: TMID-0247
Synonym:
Target:
rac-Lacosamide-d6
Cat.No: TMID-0066
Synonym:
Target:
N,N-Dimethylformamide-d7
Cat.No: TMIJ-0390
Synonym:
Target:
2-Ethyl-2-phenylmalonamide-d5
Cat.No: TMIH-0034
Synonym:
Target:
C18 Ceramide-d7
Cat.No: TMIH-0132
Synonym:
Target:
Apalutamide-13C-d3
Cat.No: TMIH-0092
Synonym:
Target:
C24 Ceramide-d7
Cat.No: TMIH-0133
Synonym:
Target:
Cyclophosphamide-d8
Cat.No: TMIJ-0264
Synonym:
Target:
Enzalutamide carboxylic acid D6
Cat.No: T19311
Synonym: MDV3100 carboxylic acid D6
Target: Others
Zonisamide-13C2,15N
Cat.No: T37847
Synonym: Zonisamide-13C2,15N
Target:
Benzamide-15N
Cat.No: T40394
Synonym: Phenylamide-15N,Benzenecarboxamide-15N,NSC-3114-15N,Benzamide-15N
Target:
Arachidonoyl Ethanolamide-d4
Cat.No: TMIH-0620
Synonym: AEA-d4
Target:
N-desmethyl Apalutamide-d4
Cat.No: TMIH-0372
Synonym:
Target:
Apalutamide-d7
Cat.No: TMIH-0094
Synonym:
Target:
4-amino-N-(4-nitrophenyl)benzenesulfonamide-d4
Cat.No: TMIH-0053
Synonym:
Target:
2-Furamide-3,4,5-d3
Cat.No: TMIH-0035
Synonym:
Target:
Enzalutamide-d6 Carboxylic Acid
Cat.No: TMIH-0218
Synonym:
Target:
(±)-Ropivacaine-d7
Cat.No: TMID-0185
Synonym:
Target:
Ropivacaine-d7
Cat.No: TMIJ-0102
Synonym:
Target:
Lidocaine-d10 (N,N-diethyl-d10)
Cat.No: TMID-0262
Synonym:
Target:
Orlistat-d3
Cat.No: T70882
Synonym:
Target:
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