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Search Results for " dose-dependent "

Targets Recommended: Others

261

抑制剂 & 化合物

86

天然产物

9

重组蛋白

4

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T22282	Brr2-IN-3 Brr2 Inhibitor 9,Brr2 Inhibitor C9	Others	Others
	Brr2-IN-3 (Brr2 Inhibitor C9) 是选择性 Brr2解旋酶变构抑制剂。它呈剂量依赖性地抑制解旋酶(IC50:1.3 μM)。
T77662	DJ4	Apoptosis	Apoptosis
	DJ4 在微摩尔范围内以剂量依赖性诱导促凋亡作用。
T31675	Esaprazole C/63	Others	Others
	Esaprazole (C/63) 对人胃黏膜具有剂量依赖性的细胞保护作用。
T30819	CGP 20376 CGP-20376,CGP20376	Others	Others
	CGP 20376 是一种苯并噻唑化合物，是一种驱虫剂，对嗜酸性粒细胞呼吸爆发的双重剂量依赖性调节体外作用，具有抗纤特性。
T68174	Sergliflozin A	SGLT	GPCR/G Protein
	Sergliflozin A 是一种选择型SGLT2抑制剂，以剂量依赖性方式诱导糖尿。可降低高血糖。
T6464	Detomidine hydrochloride 盐酸地托咪定,MPV-253 AII,Domosedan,Detomidine HCl	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Detomidine hydrochloride (MPV-253 AII) 是咪唑衍生物，是有效的 α2-肾上腺素能 (α2-adrenergic) 激动剂，可用于促进安定、缓解疼痛的研究。
T71746	Pincainide	Others	Others
	Pincainide 是一种新型β-氨基苯胺，以剂量依赖的方式抑制去甲肾上腺素血管平滑肌功能异常引起的疾病。
T16740	RH1 NSC 697726	Apoptosis	Apoptosis
	RH1 (NSC 697726) 是一种生物还原性抗癌化合物，在体外表现出剂量依赖性双相效应，在较高剂量下诱导细胞凋亡，在较低剂量下诱导衰老。
T10276	AKT Kinase Inhibitor	Akt	Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	AKT Kinase Inhibitor 是一种具有抗肿瘤活性的 Akt 抑制剂，以剂量依赖的方式选择性抑制细胞增殖。
T29955	AMC-01 AMC01,AMC 01	Antiviral; PERK	Apoptosis; Immunology/Inflammation
	AMC-01 具有潜在的抗病毒活，可通过丝氨酸残基 51 的磷酸化诱导 eIF2-α 失活，这种作用具有剂量和时间依赖性。AMC-01 可用来研究动脉粥样硬化和帕金森综合征。
T6982	SGI-7079	FLT; c-Met/HGFR; c-RET; TAM Receptor; Src	Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
	SGI7079 是 ATP-竞争性 Axl 抑制剂，能够显著抑制 SUM149 (IC50:0.43 μM)和 KPL-4 (IC50:0.16 μM)细胞增殖。
T38562	AKN-028	FLT	Angiogenesis; Tyrosine Kinase/Adaptors
	AKN-028 是酪氨酸激酶 FLT3的抑制剂，可剂量依赖性的诱导 FLT3的自磷酸化。
T3042	JAK2 Inhibitor V JAK2 Inhibitor V Z3,Z3,NSC42834	JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	JAK2 Inhibitor V (JAK2 Inhibitor V Z3) 是一种新型的 Jak2 特异性抑制剂，以剂量依赖性方式抑制 Jak2-V617F 和 Jak2-WT 自磷酸化。
T2299	BMS-833923 XL-139	Apoptosis; Hedgehog/Smoothened; Smo	Apoptosis; GPCR/G Protein; Stem Cells
	BMS-833923 (XL-139) 是一种口服生物可利用的 Smoothened 拮抗剂，以剂量依赖性方式抑制 BODIPY cyclopamine 与 SMO 的结合，IC50为21 nM。
T36478	BI-6901	CCR	Immunology/Inflammation; Microbiology/Virology
	BI-6901 是一种选择性 CCR10 拮抗剂。在DNFB接触超敏反应的小鼠模型中，BI 6901 以剂量依赖的方式显示其抗炎反应。
T15006	Dirlotapide CP742033,Slentrol	Others; CETP	Metabolism; Others
	Dirlotapide (CP742033) 是一种肠道选择性微粒体甘油三酯转移蛋白(MTP)抑制剂。它可以减轻糖尿病狗的体重。Dirlotapide 以剂量依赖性方式减少食物摄入量，可能是通过增加肽YY 释放到循环中。
T68162	Tiflucarbine Tiflucarbina	5-HT Receptor; PDE	GPCR/G Protein; Metabolism; Neuroscience
	Tiflucarbine 是一种潜在的非选择性5-HT激动剂，具有抗抑郁活性。Tiflucarbine 剂量依赖性的增加了大鼠脑中可溶性钙调蛋白（CaM）依赖性磷酸二酯酶的比活性。
T16687	Pyr3	TRP/TRPV Channel	Membrane transporter/Ion channel
	Pyr3 是一种选择性瞬时受体电位经典通道 3 抑制剂。 Pyr3 以剂量依赖性方式抑制 TRPC3 介导的 Ca2+ 内流 (IC50 = 700 nM)。
T77506	1-vinylpyrene 1-Ethenylpyrene	Others	Others
	1-vinylpyrene (1-Ethenylpyrene) 具有抗肿瘤活性，以剂量依赖性方式强烈抑制由DMBA 或B[]P 引发的皮肤肿瘤的形成，可用于预防肿瘤形成。
T3564	SHP099 SHP099 free base,SHP 099,SHP-099	Phosphatase; PERK	Apoptosis; Metabolism
	SHP099 (SHP099 free base) free base 是一种选择性的，有效的，有口服活性的 SHP2抑制剂，IC50=70 nM。
T21432	Molindone (±)-Molindone,Moban,Molindonum,SPN-810M	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Molindone ((±)-Molindone) 是一种治疗性抗精神病药物，通过阻断大脑中多巴胺的作用而用于治疗精神分裂症。Molindone 常与羟色胺联合使用，以剂量依赖性方式增加错误并降低反应率。
T3465	Vesnarinone 维司力农,OPC-8212,Arkin,Piteranometozine	HIV Protease; PDE	Metabolism; Microbiology/Virology; Proteases/Proteasome
	Vesnarinone (Arkin) 是一种喹啉酮衍生物，可抑制磷酸二酯酶III 活性，增加钙通量和减小钾通量。
T37538	Amifostine thiol WR-1065	p53	Apoptosis
	Amifostine thiol (WR-1065) 是放射保护剂，可保护 DNA 免受快速中子诱导的链断裂。Amifostine thiol 以剂量依赖性方式改善（P<0.001） 6-OHDA 诱导的僵滞，通过 JNK 依赖的信号通路激活 p53。
T72057	H1k	CDK	Cell Cycle/Checkpoint
	H1k 是一种 eudistomin Y 荧光衍生物和溶酶体靶向抗增殖剂。它可以剂量依赖性地增加自噬信号，下调细胞周期蛋白依赖性激酶(cyclin-dependent kinase, CDK1)和细胞周期蛋白 B1的表达。
T38470	Obestatin (human)
	Obestatin (human) 是一种由 preproghrelin 经过剪切形成的G蛋白欧联实体39的内源性配体，可以剂量依赖的方式抑制进食，可用于研究肥胖。
T24131	HDAC3-IN-T247 HDAC3 inhibitor T247,HDAC3 inhibitor-T247,HDAC3 IN T247,T247	Histone Demethylase; Antiviral	Chromatin/Epigenetic; Immunology/Inflammation
	HDAC3-IN-T247 (HDAC3 inhibitor T247) 是一种具有选择性和有效性的组蛋白去乙酰化酶 3（HDAC3）抑制剂，具有抗癌和抗病毒活性。HDAC3-IN-T247 以剂量依赖的方式诱导人结肠癌 HCT116 细胞中 NF-κB 乙酰化。HDAC3-IN-T247 抑制癌细胞增殖。
T64359	Anti-inflammatory agent 36	Immunology/Inflammation related	Immunology/Inflammation
	Anti-inflammatory agent 36 是一种抗炎剂。它对LPS 诱导的RAW 264.7细胞释放TNF-a 和IL-6具有剂量依赖性的抑制作用，IC50分别为3.69uM 和3.68uM。
T61349	HIF-1α-IN-2	HIF	Angiogenesis; Chromatin/Epigenetic
	HIF-1α-IN-2 是一种新型高效的 HIF-1α 抑制剂，具有抗癌抗肿瘤活性，以剂量依赖的方式抑制 HIF-1α 和 VEGF 的表达，抑制细胞迁移。
T2606	KN-93 Phosphate	CaMK	Neuroscience
	KN-93可以竞争性阻断钙调蛋白与对应激酶的结合，是一种钙离子/钙调蛋白依赖激酶 II（CaMKII）抑制剂，Ki 为370 nM。
T73440	ccc_R08	HBV	Microbiology/Virology
	ccc_R08 是一种可口服的 HBV cccDNA 抑制剂，以剂量依赖的方式降低细胞外 HBV DNA、HBsAg 和 HBeAg 水平。ccc_R08 可用于研究HBV感染。
T7294	Aramchol C20-FABAC	Others	Others
	Aramchol (C20-FABAC) 是一种胆酸和花生酸的结合物，能够降低硬脂酰辅酶 A 去饱和酶 1 (SCD1) 的活性。它具有用于非酒精性脂肪性肝病 (NAFLD) 和非酒精性脂肪性肝炎 (NASH) 的潜能。
T9878	Croconazole	Lipoxygenase; LTR	Immunology/Inflammation; Metabolism
	Croconazole 对中性粒细胞的 5-脂氧合酶 (5-LOX) 表现出剂量依赖性抑制活性。Croconazole 是一种抗真菌剂。Croconazole 对合成白三烯 B4 (LTB4) 和 5-羟基二十碳四烯酸 (5-HETE) 的 IC50 分别为 7.8 ± 1.7 和 7.6 ± 0.3 μM。
T16510	PF-915275	Dehydrogenase	Metabolism
	PF-915275 是口服有效的人 11β-羟基类固醇脱氢酶1型选择性抑制剂，Ki 为 2.3 nM，在 HEK293 细胞中的EC50为 15 nM 。它对人和猴原代肝细胞中可的松向皮质醇的转化具有剂量依赖性，EC50分别为 20 nM 和 100 nM。
T16007	MALAT1-IN-1	Others	Others
	MALAT1-IN-1 是Malat1(转移相关的肺腺癌转录本 1) 的特异性抑制剂。它能够以剂量依赖性方式调节Malat1下游基因，但对Neat1(富核丰富转录本 1) 的表达无影响。
T14341	ATN-224 四硫钼酸二胆碱,Bis(choline)tetrathiomolybdate	Others	Others
	ATN-224 (Bis(choline)tetrathiomolybdate) 抑制内皮细胞中的 SOD1 活性，这种作用呈剂量依赖性，IC50 为 17.5±3.7 nM。 ATN-224 是一种口服 Cu2+/Zn2+-超氧化物歧化酶 1 (SOD1) 抑制剂。
T21527	HBX 41108 HBX-41108,7-氯-9-氧代-9H-茚并[1,2-B]吡嗪-2,3-二甲腈	DUB; p53	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination
	HBX 41108 (HBX-41108) 是一种泛素特异性蛋白酶 7 的非竞争性抑制剂，IC50为 424 nM。它诱导 p53 依赖的凋亡，抑制 USP7 介导的 p53 去泛素化以稳定 p53 并抑制癌细胞生长。
T22821	GSK J5 GSK-J5,GSKJ5	Histone Demethylase	Chromatin/Epigenetic
	GSK J5 对血吸虫和蠕虫具有抑制作用，常被当作一种吸血虫杀虫剂。GSK J5 以剂量和时间依赖的方式促进血吸虫死亡。GSK J5 可提高血吸虫死亡率、减低成虫活力。
T4062	CAY10602	Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair
	CAY10602 是一种SIRT1激活剂，可剂量依赖性地抑制 THP-1 细胞中脂多糖对 TNF-α 的 NF-κB 依赖性诱导。
T15378L	Gemcitabine elaidate hydrochloride CO-101 hydrochloride,Gemcitabine elaidate hydrochloride(210829-30-4(free base)),Gemcitabine 5'-elaidate hydrochloride,CP-4126 hydrochloride	Others	Others
	Gemcitabine elaidate (CP-4126) hydrochloride 是 Gemcitabine 的亲脂性前药。Gemcitabine elaidate hydrochloride 通过酯酶转化为 Gemcitabine 以被磷酸化。Gemcitabine elaidate hydrochloride 可以口服给药，具有抗肿瘤活性。
T11174	(R)-Elagolix 恶拉戈利,NBI-56418	GNRH Receptor	GPCR/G Protein
	(R)-Elagolix (NBI-56418) 是口服具有活性的、选择性高的非肽类促性腺激素释放激素受体短期有效拮抗剂 (KD = 54 pM)。
T68016	Spiroglumide CR-2194	cholecystokinin	GPCR/G Protein
	Spiroglumide 是一种CCKB-胃泌素拮抗剂，能够抑制剂量依赖性五肽胃泌素诱导的酸分泌过多，其ID50为20.1（8.67-46.4）mg / kg，可用于探索胃泌素在调节人类胃酸分泌中的生理作用。
T68316	GAC0003A4 GAC0001E5	Liver X Receptor	Metabolism
	GAC0003A4 是一种有效的 LXR 反向激动剂，具有抗肿瘤活性，能抑制 LXR 蛋白的转录。GAC0003A4 可降解 LXRβ 蛋白，以剂量依赖性方式抑制PDAC细胞增殖。GAC0003A4 有用于研究晚期胰腺癌和其他顽固性恶性肿瘤。
T35941	DC-Chol hydrochloride Cholesteryl 3β-N-(dimethylaminoethyl)carbamate hydrochloride,DC-Chol (hydrochloride),DC-Cholesterol hydrochloride,Cholesteryl 3β-N-(dimethylaminoethyl)carbamate	Beta Amyloid	Neuroscience
	DC-Chol hydrochloride(DC-Cholesterol hydrochloride) 在适当的实验条件下能抑制 Aβ40 纤维的形成且以剂量依赖性的方式显著抑制氧化hCT的淀粉样蛋白形成。DC-Chol hydrochloride可诱导改善和平衡的免疫力，能够促进乙型肝炎疫苗的研究。
T40413	SW157765	transporter	Metabolism
	SW157765 是一种选择性葡萄糖转运体 GLUT8（SLC2A8）抑制剂，是很多化合物的前药，以剂量依赖性方式选择性地抑制SW157765敏感细胞中荧光 2-脱氧葡萄糖（2DG）的摄取，可用于研究肺癌。
TP1220L	ANP(1-28) Acetate (human, porcine) 醋酸卡培立肽,Carperitide acetate (89213-87-6 Free base),Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate	Endothelin Receptor	GPCR/G Protein
	Carperitide acetate (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate) 是一种由 28 个氨基酸组成的激素，由心脏产生并分泌，以响应心脏损伤和机械拉伸。Carperitide acetate 抑制内皮素-1 (endothelin-1) 分泌。
T67828	Enerisant TS-091	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Enerisant (TS-091) 是一种具有口服活性、选择性和高效性的组胺 H3 受体拮抗剂，在小鼠体内以剂量依赖的方式调节组胺H3受体。Enerisant 可促进促认知作，可逆转东莨菪碱诱导的认知障碍。
T9032	MGH-CP1	Others	Others
	MGH-CP1 是 TEAD2 (IC50:710 nM) 及 TEAD4 (IC50:672 nM) 自棕榈酰化抑制剂，口服有活性，可降低细胞内源性或异位表达的 TEAD 蛋白棕榈酰化水平。MGH-CP1 与 Lats1/2 缺失，是 Myc 的表达受到抑制，阻碍上皮细胞过度增殖，诱导细胞凋亡。
T77761	BMS-502	Others	Others
	BMS-502 是一种二酰基甘油激酶 (DGK) α 和 ζ 的强效双重抑制剂，诱导人和小鼠T细胞的免疫反应，阻断 T 细胞中细胞内检查点信号传导。BMS-502 以剂量依赖的方式刺激免疫反应，可用于研究与免疫相关的疾病。
T16868	SEC inhibitor KL-2 KL-2	Others	Others
	SEC inhibitor KL-2 (KL-2) (KL-2) 是一种拟肽先导化合物，有效的选择性 SEC 抑制剂，通过破坏 SEC 支架蛋白 AFF4 和 P-TEFb 之间的相互作用，导致 Pol II 从启动子近端暂停位点的释放受损并且进行性转录延伸的平均速率降低。SEC inhibitor KL-2 剂量依赖性地抑制 AFF4-CCNT1 相互作用，Ki 值为 1.50 μM。
T8527	CPYPP	Others	Others
	CPYPP 是DOCK2-Rac1相互作用的抑制剂。它能够结合DOCK2DHR-2结构域，并以剂量依赖性方式抑制 DOCK2DHR-2 (IC50:22.8 µM) 对 Rac1 的鸟嘌呤核苷酸交换因子活性。它还抑制DOCK180和DOCK5，对 DOCK9 的抑制作用较小。

化合物

Cat.No: T22282

Synonym: Brr2 Inhibitor 9,Brr2 Inhibitor C9

Target: Others

Cat.No: T77662

Target: Apoptosis

Cat.No: T31675

Synonym: C/63

Target: Others

Cat.No: T30819

Synonym: CGP-20376,CGP20376

Target: Others

Cat.No: T68174

Target: SGLT

Detomidine hydrochloride

Cat.No: T6464

Synonym: 盐酸地托咪定,MPV-253 AII,Domosedan,Detomidine HCl

Target: Adrenergic Receptor

Cat.No: T71746

Target: Others

Cat.No: T16740

Synonym: NSC 697726

Target: Apoptosis

AKT Kinase Inhibitor

Cat.No: T10276

Target: Akt

Cat.No: T29955

Synonym: AMC01,AMC 01

Target: Antiviral, PERK

Cat.No: T6982

Target: FLT, c-Met/HGFR, c-RET, TAM Receptor, Src

Cat.No: T38562

Target: FLT

JAK2 Inhibitor V

Cat.No: T3042

Synonym: JAK2 Inhibitor V Z3,Z3,NSC42834

Target: JAK

Cat.No: T2299

Synonym: XL-139

Target: Apoptosis, Hedgehog/Smoothened, Smo

Cat.No: T36478

Target: CCR

Cat.No: T15006

Synonym: CP742033,Slentrol

Target: Others, CETP

Cat.No: T68162

Synonym: Tiflucarbina

Target: 5-HT Receptor, PDE

Cat.No: T16687

Target: TRP/TRPV Channel

Cat.No: T77506

Synonym: 1-Ethenylpyrene

Target: Others

Cat.No: T3564

Synonym: SHP099 free base,SHP 099,SHP-099

Target: Phosphatase, PERK

Cat.No: T21432

Synonym: (±)-Molindone,Moban,Molindonum,SPN-810M

Target: Dopamine Receptor

Cat.No: T3465

Synonym: 维司力农,OPC-8212,Arkin,Piteranometozine

Target: HIV Protease, PDE

Amifostine thiol

Cat.No: T37538

Synonym: WR-1065

Target: p53

Cat.No: T72057

Target: CDK

Obestatin (human)

Cat.No: T38470

Cat.No: T24131

Synonym: HDAC3 inhibitor T247,HDAC3 inhibitor-T247,HDAC3 IN T247,T247

Target: Histone Demethylase, Antiviral

Anti-inflammatory agent 36

Cat.No: T64359

Target: Immunology/Inflammation related

Cat.No: T61349

Target: HIF

KN-93 Phosphate

Cat.No: T2606

Target: CaMK

Cat.No: T73440

Target: HBV

Cat.No: T7294

Synonym: C20-FABAC

Target: Others

Cat.No: T9878

Target: Lipoxygenase, LTR

Cat.No: T16510

Target: Dehydrogenase

Cat.No: T16007

Target: Others

Cat.No: T14341

Synonym: 四硫钼酸二胆碱,Bis(choline)tetrathiomolybdate

Target: Others

Cat.No: T21527

Synonym: HBX-41108,7-氯-9-氧代-9H-茚并[1,2-B]吡嗪-2,3-二甲腈

Target: DUB, p53

Cat.No: T22821

Synonym: GSK-J5,GSKJ5

Target: Histone Demethylase

Cat.No: T4062

Target: Sirtuin

Gemcitabine elaidate hydrochloride

Cat.No: T15378L

Synonym: CO-101 hydrochloride,Gemcitabine elaidate hydrochloride(210829-30-4(free base)),Gemcitabine 5'-elaidate hydrochloride,CP-4126 hydrochloride

Target: Others

Cat.No: T11174

Synonym: 恶拉戈利,NBI-56418

Target: GNRH Receptor

Cat.No: T68016

Synonym: CR-2194

Target: cholecystokinin

Cat.No: T68316

Synonym: GAC0001E5

Target: Liver X Receptor

DC-Chol hydrochloride

Cat.No: T35941

Synonym: Cholesteryl 3β-N-(dimethylaminoethyl)carbamate hydrochloride,DC-Chol (hydrochloride),DC-Cholesterol hydrochloride,Cholesteryl 3β-N-(dimethylaminoethyl)carbamate

Target: Beta Amyloid

Cat.No: T40413

Target: transporter

ANP(1-28) Acetate (human, porcine)

Cat.No: TP1220L

Synonym: 醋酸卡培立肽,Carperitide acetate (89213-87-6 Free base),Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate

Target: Endothelin Receptor

Cat.No: T67828

Synonym: TS-091

Target: Histamine Receptor

Cat.No: T9032

Target: Others

Cat.No: T77761

Target: Others

SEC inhibitor KL-2

Cat.No: T16868

Synonym: KL-2

Target: Others

Cat.No: T8527

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN1182	11-Keto-beta-boswellic acid 11-Keto-beta-boswellic acid,11-酮基-BETA-乳香酸	Leukotriene Receptor; NF-κB; Lipoxygenase	GPCR/G Protein; Metabolism; NF-κB
	11-Keto-beta-boswellic acid 是来自乳香的一种五环三萜酸，具有抗炎活性和剂量依赖性心脏保护作用，主要是由于抑制5-脂氧合酶、白三烯、NF-κB 的激活和肿瘤坏死因子 α 的产生。
T6985	Benzo[a]pyrene 苯并[a]芘,3,4-Benzopyrene,苯并(a)芘	Others	Others
	Benzo[a]pyrene (3,4-Benzopyrene) 在动物模型中显示肺致癌性，可用于化学预防研究。
TN1071	Ophiopogonin D'	Sirtuin; UGT	Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
	Ophiopogonin D'可以以剂量依赖性方式激活 SIRT1。 Ophiopogonin D'也非竞争性地抑制 UGT1A6 和 UGT1A10。
TN7126	N-Vanillyloctanamide	Others	Others
	N-Vanillyloctanamide 是一种来自 Capsicum annuum L. var. 果实的辣椒素。年鉴。 N-Vanillyloctanamide 减少 Lactuca sativa 幼苗的自由基长度，这种抑制是剂量依赖性的。
T4241	Rubiadin 1,3-Dihydroxy-2-Methylanthracene-9,10-Dione,茜根定,茜草素	Free radical scavengers; PARP; Caspase	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; oxidation-reduction; Proteases/Proteasome
	Rubiadin (1,3-Dihydroxy-2-Methylanthracene-9,10-Dione) 是一种二羟基蒽醌，提取自茜草，具有抗氧化剂作用。
TN1558	N-Vanillyldecanamide 癸酸香草酰胺,Decylic acid vanillylamide	Others	Others
	N-Vanillyldecanamide (Decylic acid vanillylamide) 分离自辣椒果实，以剂量依赖的方式显著减小紫花苜蓿幼苗的自由基长度。
T6S1843	Tenacissoside I 通关藤苷I,Tenacissimoside B	Others	Others
	Tenacissoside I (Tenacissimoside B) 是一种 C21 甾体，来自于Marsdenia tenacissima 中，在M. tenacissima 含量较高。
TN2058	Persicogenin	Anti-infection	Microbiology/Virology
	Persicogenin 是分离自 Rhus retinorrhoea 中，具有抗癌作用。
T4S0590	Columbin	Phospholipase; COX; Parasite	Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience
	Columbin 是有口服活性的二萜呋喃内酯，选择性抑制COX-1和COX-2，EC50值为 327 μM 和 53.1 μM，具有抗炎和抗锥虫体作用。
TN1258	3-Acetyl-beta-boswellic acid 3-O-Acetyl-beta-boswellic acid,3-乙酰基-BETA-乳香酸	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	3-Acetyl-beta-boswellic acid 是一种乳香酸，分离自乳香锯缘胶树脂。
T4S1718	Punicalin	HBV; HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Punicalin 是从Punica granatumL. 或Terminalia catappaL. 的叶子中分离的，一种可水解的单宁，具有抗炎活性。它是一种抗乙型肝炎病毒药物。
T7090	Jionoside A1 焦地黄苯乙醇甙A1,焦地黄苯乙醇苷A1	Others	Others
	Jionoside A1 分离自Radix Rehmanniae Praeparata 中，具有剂量依赖性免疫增强作用，并对 H2O2处理的 SH-SY5Y 细胞具有中等保护活性。
TN7236	Cephalandole B	IL Receptor	Immunology/Inflammation
	cephalandole B 是一种从青黛中分离出两种吲哚生物碱，能明显地抑制了IL-17A 基因的表达，以剂量依赖的方式抑制了Jukat 细胞的IL-17A 荧光素酶报告。
T4S1540	Myrislignan	Apoptosis; NF-κB	Apoptosis; NF-κB
	Myrislignan 是一种木酚素，从Myristica fragransHoutt 分离得到，具有抗炎作用。它通过抑制NF-kB 信号通路的激活，减轻LPS 诱导的小鼠巨噬细胞炎症反应。
T3729	Ethyl gallate Nipagallin A,Phyllemblin,gallic acid ethyl ester,没食子酸乙酯	MMP; NF-κB; Akt; Antibacterial	Cytoskeletal Signaling; Microbiology/Virology; NF-κB; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Ethyl gallate (gallic acid ethyl ester) 是一种非类黄酮酚过氧化氢清除剂。
T6S1256	Ruscogenin	NOS; NF-κB; NOD-like Receptor (NLR)	Immunology/Inflammation; NF-κB
	Ruscogenin 是一种重要甾体皂苷元，提取自麦冬。它能够抑制 TXNIP/NLRP3炎症体激活和 MAPK 途径，改善脑缺血诱导的血脑屏障功能障碍，具有显著抗血栓、抗炎作用。
T5120	Rhamnose 6-Deoxyhexopyranose,L-鼠李糖,6-Deoxy-L-mannose,alpha-L-Rhamnose	Calcium Channel; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism
	alpha-L-Rhamnose (6-Deoxy-L-mannose) 是存在植物和细菌中的一种单糖。Rhamnose- 免疫原连接物能被用于免疫疗法。Rhamnose 能通过胞外途径穿过上皮细胞，能够作为肠吸收的标志。
TN4761	Phellamurin	P-gp	Membrane transporter/Ion channel; Neuroscience
	Phellamurin 是一种来自黄檗叶的黄酮糖苷，可诱导细胞凋亡，具有抗肿瘤活性。它抑制肠道 P-糖蛋白，还抑制凤蝶的产卵。
T36473	trans-Nerolidol	Antifungal	Microbiology/Virology
	trans-Nerolidol 是从撒哈拉瓦莲属植物的地上部分分离出来的倍半萜醇，具有抗真菌活性。trans-Nerolidol 以剂量依赖性方式抑制细胞增殖，诱导细胞周期停滞在 G1 期
T5S0106	Peimisine 贝母辛,Ebeiensine	RAAS; AChR	Endocrinology/Hormones; Neuroscience
	Peimisine (Ebeiensine) 非竞争性拮抗气管平滑肌 M 受体，抑制 Ach 引起的平滑肌收缩。它兴奋 β 受体和拮抗内钙释放，促进一氧化氮释放，可舒张气管平滑肌，有平喘作用。
T5S0761	Nitidine chloride	Apoptosis; ERK; FAK; p38 MAPK; NF-κB; Topoisomerase; STAT; Parasite	Angiogenesis; Apoptosis; Cytoskeletal Signaling; DNA Damage/DNA Repair; JAK/STAT signaling; MAPK; Microbiology/Virology; NF-κB; Stem Cells; Tyrosine Kinase/Adaptors
	Nitidine chloride 是从Zanthoxylum nitidum (Roxb) DC 中分离得到的，具有抗疟疾活性。它通过多个靶点通路，起抗癌作用，抑制STAT3、DNA 拓扑异构酶1和2A、ERK 和c-Src/FAK 相关信号通路。它通过MAPK 和NF-kB 途径抑制Lps 诱导的炎性细胞因子的产生。
TCS1372	Atraric acid	Phosphatase; Androgen Receptor	Endocrinology/Hormones; Metabolism
	Atraric acid 衍生物作为一种新的化学先导结构，用于作为 AR 拮抗剂的新型治疗化合物，可用于预防或治疗前列腺疾病。它以剂量依赖性方式抑制 PTP1B 活性，IC50 值为 51.5 uM，表明阿特拉酸具有治疗糖尿病的潜力。
TN1742	Homovanillyl alcohol 高香草醇,4-羟基-3-甲氧基苯乙醇	TNF; Drug Metabolite	Apoptosis; Metabolism
	Homovanillyl alcohol 是羟基酪醇的生物代谢物。Hydroxytyrosol 是存在于原始橄榄油和葡萄酒中的酚类化合物。它能够保护红细胞免受氧化损伤，并对心血管具有保护作用。
TN1674	Garcinone D 伽升沃 D	Reactive Oxygen Species; Nrf2; STAT	Immunology/Inflammation; JAK/STAT signaling; Metabolism; NF-κB; Stem Cells
	Garcinone D 是来自山竹的一种呫吨酮，可促进 C17.2 神经干细胞的增殖。它以浓度和时间依赖的方式增加磷酸化信号转导和转录激活因子 3 (p-STAT3)、Cyclin D1 和核因子红细胞 2 相关因子 (Nrf2)、以及血红素加氧酶-1 (HO-1) 的蛋白质水平。
T3S0645	N-trans-Feruloyltyramine Feruloyltyramine,N-Feruloyltyramine,Moupinamide,N-反式阿魏酰酪胺	Others; COX	Immunology/Inflammation; Neuroscience; Others
	N-trans-Feruloyltyramine (Feruloyltyramine) 是从大麻中分离得到的一种生物碱，是COX1和COX2的抑制剂，具有抗氧化和抗炎活性。
T2S1837	Steviol 甜菊醇,NSC 226902,Hydroxydehydrostevic acid	Others	Others
	Steviol (NSC-226902) 是一种甜菊糖甙的主要代谢物。它能降低 AQP2 的表达，并促进 AQP2 的降解，从而减缓肾囊肿的生长。
TN3972	Epimedokoreanin B	Apoptosis; Others; Antibacterial	Apoptosis; Microbiology/Virology; Others
	Epimedokoreanin B （EKB）是一种从韩国淫羊藿中分离出的异戊烯化类黄酮，在人非小细胞肺癌（NSCLC）A549和NCI-H292细胞中展现出抗癌活性。Epimedokoreanin B 还具有抗炎和抗菌活性，可有清除 DPPH 自由基的活性，能以剂量依赖的方式抑制 MCF-7 和 HepG2 的增殖。Epimedokoreanin B 能显著抑制 N (δ) -（羧甲基）赖氨酸（CML）和 N (Ï) -（羧甲基）精氨酸（CMA）的形成，可通过抑制高级糖化终产物（AGEs）预防糖尿病的临床并发症。
TWO2727	Propane-1,2,3-triyl tripalmitate Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate,三棕榈酸甘油酯	Others; Endogenous Metabolite	Metabolism; Others
	Propane-1,2,3-triyl tripalmitate (Glycerol Tripalmitate) 是内源性代谢产物的一种。
T3S2312	Poncirin 枸橘苷,Isosakuranetin-7-neohesperidoside	Apoptosis; Others	Apoptosis; Others
	Poncirin (Isosakuranetin-7-neohesperidoside) 是从三叶草中分离出来的一种天然产物，具有抗炎活性。它防止脂肪生成，增强间充质干细胞中的成骨细胞分化，增加骨矿物质密度，改善小梁微结构，可能反映 GIO 小鼠的骨形成增加和骨吸收减少。
T7027	EURYCOMANONE 东革阿里提取物,Pasakbumin A	Others	Others
	Eurycomanone (Pasakbumin A) 能够抑制雌激素生成过程中磷酸二酯酶和芳香酶的活性，促进精子生成。它对 HepG2 细胞具有细胞毒性，能够上调 p53 和 Bax 以及下调 Bcl-2 ，诱导细胞凋亡。它具有抗癌活性，在浓度范围内以剂量依赖性方式抑制 A549 肺癌细胞增殖从 5 到 20 微克/毫升。
T2S2043	Dracorhodin perchlorate Dracorhodin perochlorate,血竭素高氯酸盐,Dracohodin perochlorate	Apoptosis; Others	Apoptosis; Others
	Dracorhodin perchlorate 是来源于中药血竭的一种天然产物。它抑制细胞生长，并以剂量和时间依赖性方式诱导成纤维细胞凋亡，将细胞周期阻滞在 G1 期，可作为抗乳腺癌的候选药物。
T6S0653	Linarin Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine,蒙花苷	TNF; AChE	Apoptosis; Neuroscience
	Linarin (Acacetin-7-O-rutinoside) 是一种选择性的乙酰胆碱酯酶 (AChE) 抑制剂，从薄荷花提取物中分离得到。
T5S1097	Neferine (R)-1,2-Dimethoxyaporphine,(-)-Neferine,甲基莲心碱	Apoptosis; NF-κB; Autophagy	Apoptosis; Autophagy; NF-κB
	Neferine ((-)-Neferine) 是一种双苄基异喹啉类生物碱，可强效抑制NF-κB 激活，具有抗肿瘤活性。
TN6926	Paeonoside	Others	Others
	Paeonoside 发现与P. suffruticosa 中，具有生物活性，可以促进成骨细胞分化过程中的伤口愈合和迁移。Paeonoside 具有一定的抗糖尿病活性，可防止脓毒症和败血症引起的死亡。Paeonoside 对 MC3T3-E1细胞的前成骨细胞没有细胞毒性作用，以剂量依赖性的方式显著恢复伤口区域并促进细胞迁移和促进碱性磷酸酶（ALP）染色及其活性。
T6S1917	Schisandrol B Gomisin A,TJN-101,Besigomsin,五味子醇乙,Gamma-Schisandrin,戈米辛A,Schizandrol B,Wuweizi alcohol-B	P450; Reactive Oxygen Species; Autophagy	Autophagy; Immunology/Inflammation; Metabolism; NF-κB
	Schisandrol B (Besigomsin) 是华中五味子的主要活性成分，具有保肝、抗炎、抗糖尿病和抗氧化的作用。它抑制活性氧的产生，也抑制 P-糖蛋白和CYP3A 的活性。
T4S0498	Glaucocalyxin A 蓝萼甲素,Wangzaozin B,Leukamenin F	Apoptosis; Akt; Caspase; PI3K	Apoptosis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Glaucocalyxin A (Leukamenin F) 是来自日本黑纹病菌的一种对映型月桂基二萜，具有抗肿瘤作用。它通过调节PI3K/Akt 信号通路抑制 GLI1 的核易位，诱导骨肉瘤凋亡。
T0256	Citric acid trilithium salt tetrahydrate Lithium citrate tribasic tetrahydrate,柠檬酸三锂盐四水合物,Trilithium citrate tetrahydrate	Dehydrogenase; GSK-3; HIF/HIF Prolyl-Hydroxylase; Antibacterial; GluR	Chromatin/Epigenetic; Metabolism; Microbiology/Virology; Neuroscience; PI3K/Akt/mTOR signaling; Stem Cells
	Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) 是一种用于治疗精神疾病的药物。它也是一种医药和建筑材料, 可用于氨基酸定量分析时的梯度洗脱。
T3794	Pentagalloylglucose Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose,1,2,3,4,6-五没食子酰葡萄糖	Influenza Virus	Microbiology/Virology
	1,2,3,4,6-O-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) 存在于多种植物中，具有重要的药理作用。Pentagalloylglucose 表现出显著的抗狂犬病病毒 (RABV) 活性。
TN3973	Epinodosin	Others	Others
	Epinodosin induces significant DNA damage to HepG2 cells in a time- and dose-dependent manner.Epinodosin has a biphasic, dose-dependent effect on root growth and a strong inhibitory effect on root hair development in Lactuca sativa L. seedlings.
TN4513	Meliasenin B	Others	Others
	Meliasenin B may cause hepatotoxicity, it displays dose-dependent toxicity on HepG2 cells.
TN6527	(R)-O-isobutyroyllomatin
	(R)-O-isobutyroyllomatin shows significant dose-dependent protection against oxidative stress, it also exhibits cell proliferative effects.
T13618	Citreoviridin	Others	Others
	Citreoviridin, a toxin from Penicillium citreoviride NRRL 2579, inhibits brain synaptosomal Na+/K+-ATPase whereas, in microsomes, both Na+/K+-ATPase and Mg2+-ATPase activities are significantly stimulated in a dose-dependent manner.
TN2990	3alpha-dihydrocadambine	Others	Others
	3alpha-Dihydrocadambine exhibits dose-dependent hypotensive and anti-hypertensive effects in anesthetized normotensive rats and in conscious spontaneously hypertensive rats.
TN2747	2-Acetoxy-3-deacetoxycaesaldekarin E	Antifection	Microbiology/Virology
	2-Acetoxy-3-deacetoxycaesaldekarin E shows significant dose-dependent inhibitory effects on Plasmodium falciparum FCR-3/A2 growth in vitro.
TN5192	Tuberosin	NOS; Glucokinase	Immunology/Inflammation; Metabolism
	Tuberosin shows anti-inflammatory and antioxidant activities.It demonstrated a significantly potent inhibition on yeast α-glucosidase in a dose dependent manner.
TN3653	Cimidahurinine	BCL; ROS	Apoptosis; Immunology/Inflammation
	Cimidahurinine can attenuate Doxorubicin (DOX)-induced cardiotoxicity in a dose-dependent manner with EC50 values of 45.79 uM; it protects against cardiotoxicity by decreasing reactive oxygen species (ROS) accumulation and downregulating apoptosis-related Bax/Bcl-2 proteins.
TN3563	Caesalmin B	Antifection	Microbiology/Virology
	Caesalmin B shows significant dose-dependent inhibitory effects on Plasmodium falciparum FCR-3/A2 growth in vitro.
TN3621	Centrolobol	Caspase	Apoptosis; Proteases/Proteasome
	(-)-Centrolobol has antifibrotic activity, it can significantly inhibit the proliferation of HSC-T6 cells in a dose-dependent manner. Centrolobol exhibits strong cytotoxic activity against KB cell line.
TN4443	Lipiferolide	Telomerase; Antifection	DNA Damage/DNA Repair; Microbiology/Virology
	Lipiferolide is an inhibitor of farnesyl protein transferase(FPTase), it inhibits the FPTase activity in a dose-dependent manner, and shows cell growth inhibitory activity against several tumor cells, it possesses cytotoxic activity against KB cells. Liriodenine also has antiplasmodial activity.
T82055	Ipalbidine
	Ipalbidine为自ipomoea Hardwickii Hemsl中提炼的生物碱，显示出剂量依赖性镇痛效果。
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天然产物

11-Keto-beta-boswellic acid

Cat.No: TN1182

Synonym: 11-Keto-beta-boswellic acid,11-酮基-BETA-乳香酸

Target: Leukotriene Receptor, NF-κB, Lipoxygenase

Cat.No: T6985

Synonym: 苯并[a]芘,3,4-Benzopyrene,苯并(a)芘

Target: Others

Ophiopogonin D'

Cat.No: TN1071

Target: Sirtuin, UGT

N-Vanillyloctanamide

Cat.No: TN7126

Target: Others

Cat.No: T4241

Synonym: 1,3-Dihydroxy-2-Methylanthracene-9,10-Dione,茜根定,茜草素

Target: Free radical scavengers, PARP, Caspase

N-Vanillyldecanamide

Cat.No: TN1558

Synonym: 癸酸香草酰胺,Decylic acid vanillylamide

Target: Others

Tenacissoside I

Cat.No: T6S1843

Synonym: 通关藤苷I,Tenacissimoside B

Target: Others

Cat.No: TN2058

Target: Anti-infection

Cat.No: T4S0590

Target: Phospholipase, COX, Parasite

3-Acetyl-beta-boswellic acid

Cat.No: TN1258

Synonym: 3-O-Acetyl-beta-boswellic acid,3-乙酰基-BETA-乳香酸

Target: DNA/RNA Synthesis

Cat.No: T4S1718

Target: HBV, HIV Protease

Cat.No: T7090

Synonym: 焦地黄苯乙醇甙A1,焦地黄苯乙醇苷A1

Target: Others

Cat.No: TN7236

Target: IL Receptor

Cat.No: T4S1540

Target: Apoptosis, NF-κB

Cat.No: T3729

Synonym: Nipagallin A,Phyllemblin,gallic acid ethyl ester,没食子酸乙酯

Target: MMP, NF-κB, Akt, Antibacterial

Cat.No: T6S1256

Target: NOS, NF-κB, NOD-like Receptor (NLR)

Cat.No: T5120

Synonym: 6-Deoxyhexopyranose,L-鼠李糖,6-Deoxy-L-mannose,alpha-L-Rhamnose

Target: Calcium Channel, Endogenous Metabolite

Cat.No: TN4761

Target: P-gp

trans-Nerolidol

Cat.No: T36473

Target: Antifungal

Cat.No: T5S0106

Synonym: 贝母辛,Ebeiensine

Target: RAAS, AChR

Nitidine chloride

Cat.No: T5S0761

Target: Apoptosis, ERK, FAK, p38 MAPK, NF-κB, Topoisomerase, STAT, Parasite

Cat.No: TCS1372

Target: Phosphatase, Androgen Receptor

Homovanillyl alcohol

Cat.No: TN1742

Synonym: 高香草醇,4-羟基-3-甲氧基苯乙醇

Target: TNF, Drug Metabolite

Cat.No: TN1674

Synonym: 伽升沃 D

Target: Reactive Oxygen Species, Nrf2, STAT

N-trans-Feruloyltyramine

Cat.No: T3S0645

Synonym: Feruloyltyramine,N-Feruloyltyramine,Moupinamide,N-反式阿魏酰酪胺

Target: Others, COX

Cat.No: T2S1837

Synonym: 甜菊醇,NSC 226902,Hydroxydehydrostevic acid

Target: Others

Epimedokoreanin B

Cat.No: TN3972

Target: Apoptosis, Others, Antibacterial

Propane-1,2,3-triyl tripalmitate

Cat.No: TWO2727

Synonym: Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate,三棕榈酸甘油酯

Target: Others, Endogenous Metabolite

Cat.No: T3S2312

Synonym: 枸橘苷,Isosakuranetin-7-neohesperidoside

Target: Apoptosis, Others

Cat.No: T7027

Synonym: 东革阿里提取物,Pasakbumin A

Target: Others

Dracorhodin perchlorate

Cat.No: T2S2043

Synonym: Dracorhodin perochlorate,血竭素高氯酸盐,Dracohodin perochlorate

Target: Apoptosis, Others

Cat.No: T6S0653

Synonym: Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine,蒙花苷

Target: TNF, AChE

Cat.No: T5S1097

Synonym: (R)-1,2-Dimethoxyaporphine,(-)-Neferine,甲基莲心碱

Target: Apoptosis, NF-κB, Autophagy

Cat.No: TN6926

Target: Others

Cat.No: T6S1917

Synonym: Gomisin A,TJN-101,Besigomsin,五味子醇乙,Gamma-Schisandrin,戈米辛A,Schizandrol B,Wuweizi alcohol-B

Target: P450, Reactive Oxygen Species, Autophagy

Glaucocalyxin A

Cat.No: T4S0498

Synonym: 蓝萼甲素,Wangzaozin B,Leukamenin F

Target: Apoptosis, Akt, Caspase, PI3K

Citric acid trilithium salt tetrahydrate

Cat.No: T0256

Synonym: Lithium citrate tribasic tetrahydrate,柠檬酸三锂盐四水合物,Trilithium citrate tetrahydrate

Target: Dehydrogenase, GSK-3, HIF/HIF Prolyl-Hydroxylase, Antibacterial, GluR

Pentagalloylglucose

Cat.No: T3794

Synonym: Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose,1,2,3,4,6-五没食子酰葡萄糖

Target: Influenza Virus

Cat.No: TN3973

Target: Others

Cat.No: TN4513

Target: Others

(R)-O-isobutyroyllomatin

Cat.No: TN6527

Cat.No: T13618

Target: Others

3alpha-dihydrocadambine

Cat.No: TN2990

Target: Others

2-Acetoxy-3-deacetoxycaesaldekarin E

Cat.No: TN2747

Target: Antifection

Cat.No: TN5192

Target: NOS, Glucokinase

Cat.No: TN3653

Target: BCL, ROS

Cat.No: TN3563

Target: Antifection

Cat.No: TN3621

Target: Caspase

Cat.No: TN4443

Target: Telomerase, Antifection

Cat.No: T82055

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02853	FAM3B Protein, Mouse, Recombinant (hFc) Fam3b,Cytokine-like protein 2-21,Protein FAM3B,Pancreatic-de...	Mouse	HEK293 Cells
	Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner.
TMPH-02852	FAM3B Protein, Mouse, Recombinant (His & Myc) Fam3b,Cytokine-like protein 2-21,Protein FAM3B,Pancreatic-de...	Mouse	Baculovirus Insect Cells
	Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner.
TMPH-02885	SOSTDC1 Protein, Mouse, Recombinant (His & Myc) Sclerostin-like protein,Sostdc1,Sclerostin domain-containing...	Mouse	E. coli
	May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction. Enhances Wnt signaling and inhibits TGF-beta signaling. Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner.
TMPH-03367	SOSTDC1 Protein, Rat, Recombinant (His & Myc) Sostdc1,Sclerostin domain-containing protein 1,Wnt-signaling...	Rat	HEK293 Cells
	Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner. May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction. Enhances Wnt signaling and inhibits TGF-beta signaling. SOSTDC1 Protein, Rat, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 24.6 kDa and the accession number is Q642G2.
TMPJ-00019	CCL28 Protein, Human, Recombinant Small-Inducible Cytokine A28,Protein CCK1,CCL28,SCYA28,C-C M...	Human	E. coli
	Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCR10 (GPR2 orphan receptor) is also the receptor for CCL27/CTACK. CCL28 is preferentially expressed by epithelial cells of diverse tissues, with highest expression level in normal and pathological colon. It is also expresse...
TMPY-02499	Cofilin 2 Protein, Human, Recombinant (His) cofilin 2 (muscle),NEM7	Human	E. coli
	Cofilin 2 (muscle), also known as CFL2, is a member of cofilin family of the actin-binding protein superfamily. Cofilin2 shows significant homology to the other two members: cofilin 1 and DSTN, through its entire sequence, and contains residues conserved among the cofilin family that are responsible for actin-binding. Cofilin 2 (CFL2) is an important regulator of striated myocyte function. Purified cofilin 2 depolymerized actin filaments in a dose- and pH-dependent manner and reduced the apparen...
TMPY-02891	PSG6 Protein, Human, Recombinant (His) PSG12,PSG6,PSBG-6,pregnancy specific β-1-glycoprotein 6,PSG1...	Human	Baculovirus Insect Cells
	PSG6 is a pregnancy-specific glycoprotein(PSG). PSGs are secreted proteins produced by the rodent and primate placenta and play a critical role in pregnancy success. The levels of PSGs are highest during the third trimester of pregnancy, a time marked by the most profound suppression of MS disease attacks. PSGs regulate T-cell function. The regulation of T-cell function during pregnancy is likely the result of significant hormonal changes and may well involve immunoregulatory proteins derived fr...
TMPY-01033	IL-32 Protein, Human, Recombinant (isoform alpha, His) IL-32δ,IL-32beta,IL32,TAIFc,IL-32γ,白介素,IL-32 Protein(isoform...	Human	HEK293 Cells
	IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathways. It is regulated robustly by other major proinflammatory cytokines and is crucial to inflammation and immune responses. Four of the IL-32 isoforms (alpha, beta, gamma, and delta) are the most representative IL-32 transcripts, and the gamma isoform of IL-32 is the most active,...
TMPY-02246	HB-EGF Protein, Human, Recombinant DTSF,DTR,HEGFL,heparin-binding EGF-like growth factor,DTS	Human	Baculovirus Insect Cells
	Heparin-binding EGF-like growth factor (HBEGF), a member of the EGF family of growth factors, exerts its biological activity through activation of the EGFR and other ErbB receptors. Soluble mature HBEGF is proteolytically processed from a larger membrane-anchored precursor and is a potent mitogen and chemotactic factor for fibroblasts, smooth muscle cells but not endothelial cells. HBEGF activates two EGF receptor subtypes, HER1 and HER4, and binds to cell surface HSPG. The transmembrane form of...

重组蛋白

FAM3B Protein, Mouse, Recombinant (hFc)

Cat.No: TMPH-02853

Species: Mouse

Expression System: HEK293 Cells

FAM3B Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02852

Species: Mouse

Expression System: Baculovirus Insect Cells

SOSTDC1 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02885

Species: Mouse

Expression System: E. coli

SOSTDC1 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03367

Species: Rat

Expression System: HEK293 Cells

CCL28 Protein, Human, Recombinant

Cat.No: TMPJ-00019

Species: Human

Expression System: E. coli

Cofilin 2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02499

Species: Human

Expression System: E. coli

PSG6 Protein, Human, Recombinant (His)

Cat.No: TMPY-02891

Species: Human

Expression System: Baculovirus Insect Cells

IL-32 Protein, Human, Recombinant (isoform alpha, His)

Cat.No: TMPY-01033

Species: Human

Expression System: HEK293 Cells

HB-EGF Protein, Human, Recombinant

Cat.No: TMPY-02246

Species: Human

Expression System: Baculovirus Insect Cells

Cat. No.	Product Name	Target	Signaling Pathways
T37928	13C6 Glucosylsphingosine (d18:1)
	13C6 Glucosylsphingosine (d18:1) is an isotopically enriched form of 1-β-D-glucosylsphingosine (d18:1) that is intended for use as an internal standard for the quantification of 1-β-D-glucosylsphingosine by GC- or LC-MS. 1-β-D-Glucosylsphingosine is a lysolipid derivative of glucosylcerebroside that decreases activity of glucocerebrosidase in LA-N-2 cells in a dose-dependent manner.
T71328	Theobromine-d6
	Theobromine-d6 is intended for use as an internal standard for the quantification of theobromine by GC- or LC-MS. Theobromine is a methylxanthine alkaloid and derivative of caffeine that has been found in cocoa beans and has diverse biological activities. It is an adenosine A1 receptor antagonist. Theobromine increases AMPK phosphorylation and inhibits adipocyte differentiation, ERK and JNK phosphorylation, and IL-6 and TNF-α production in 3T3-L1 preadipocytes cultured in differentiation medium....
T35591	Guanfacine-13C,15N3 Guanfacine-13C,15N3
	Guanfacine-13C,15N3is intended for us as an internal standard for the quantification of guanfacine by GC- or LC-MS. Guanfacine is an α2-adrenergic receptor (α2-AR) agonist with Kivalues of 93, 1,380, and 3,890 nM for α2A-, α2B-, and α2C-ARs, respectively, in a radioligand binding assay.1It has EC50values of 52, 288, and 602 nM for α2A-, α2B-, and α2C-ARs, respectively, for stimulated [35S]GTPγS binding. It also binds to imidazoline receptor 1 (Ki= 19 nM in a radioligand binding assay).2Guanfacin...
T36537	Nitrofurantoin-13C3 Nitrofurantoin-13C3
	Nitrofurantoin-13C3is intended for use as an internal standard for the quantification of nitrofurantoin by GC- or LC-MS. Nitrofurantoin is a nitrofuran antibiotic.1In vivo, nitrofurantoin (25-100 mg/kg) reducesE. colireplication and abscess formation in the renal medulla of infected rats in a dose-dependent manner. It prevents kidney and bladder infection in rats following bladder inoculation with clinical isolates ofP. mirabilis. Nitrofurantoin also prevents alkalization of urine, as well as ca...

同位素标记化合物

13C6 Glucosylsphingosine (d18:1)

Cat.No: T37928

Cat.No: T71328

Guanfacine-13C,15N3

Cat.No: T35591

Synonym: Guanfacine-13C,15N3

Nitrofurantoin-13C3

Cat.No: T36537

Synonym: Nitrofurantoin-13C3

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