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Search Results for " cell membrane "
Targets Recommended: Hippo pathway

204

抑制剂 & 化合物

44

天然产物

13

化合物库

1

TargetMol 试剂盒

351

重组蛋白

8

同位素标记化合物

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Cat. No. Product Name
L1310 细胞骨架化合物库

759 compounds
759 种细胞骨架相关的化合物,可以用于高通量和高内涵筛选;
L8700 铁死亡化合物库

779 compounds
779 种与铁死亡通路相关的化合物,可用于高通量和高内涵筛选;
L7000 活性脂质化合物库

385 compounds
385 种生物活性小分子化合物,用于高通量、高内涵筛选;
L1500 GPCR靶点分子库

1940 compounds
1940 种与 G 蛋白及其耦联受体相关的生物活性小分子化合物,所有小分子都具有良好的生物和药理活性,部分是 FDA 批准的上市药物;
L1510 核受体化合物库

531 compounds
531 个核受体作用化合物的独特集合,可用于高通量筛选和高内涵筛选;
L8720 细胞焦亡化合物库

1066 compounds
1066 种细胞焦亡相关的化合物,可以用于细胞焦亡相关研究。
L2610 神经递质受体化合物库

1513 compounds
1513 种与神经递质受体相关的化合物,用于高通量、高内涵筛选;
L8110 细胞重编程化合物库

1813 compounds
1813 种重编程信号通路相关的生物活性小分子化合物的特有集合,可用于高通量、高内涵筛选
L7400 钠通道分子库

118 compounds
118 种钠通道相关化合物的独特集合,可用于高通量筛选和高内涵筛选;
L1300 PI3K/Akt/mTOR 化合物库

420 compounds
420 种与PI3K/Akt/mTOR 相关的生物活性小分子化合物的特有集合,用于PI3K/Akt/mTOR 相关研究以及高通量、高内涵筛选;
L1580 GPCR库Plus

338 compounds
338 种GPCR 靶向、结构新颖的化合物;
L8600 泛素化化合物库

210 compounds
210 种泛素化相关的小分子,用于高通量和高内涵筛选;
L5300 线粒体靶向库

812 compounds
812 种具有潜在或确定线粒体靶向活性的化合物,以促进针对线粒体的药物研究;

化合物库

细胞骨架化合物库
Cat.No: L1310
Compounds: 759
铁死亡化合物库
Cat.No: L8700
Compounds: 779
活性脂质化合物库
Cat.No: L7000
Compounds: 385
GPCR靶点分子库
Cat.No: L1500
Compounds: 1940
核受体化合物库
Cat.No: L1510
Compounds: 531
细胞焦亡化合物库
Cat.No: L8720
Compounds: 1066
神经递质受体化合物库
Cat.No: L2610
Compounds: 1513
细胞重编程化合物库
Cat.No: L8110
Compounds: 1813
钠通道分子库
Cat.No: L7400
Compounds: 118
PI3K/Akt/mTOR 化合物库
Cat.No: L1300
Compounds: 420
GPCR库Plus
Cat.No: L1580
Compounds: 338
泛素化化合物库
Cat.No: L8600
Compounds: 210
线粒体靶向库
Cat.No: L5300
Compounds: 812
Cat. No. Product Name Form Specificity Of Inhibition
C0052 Penicillin-Streptomycin-Amphotericin B Solution (100×), Sterile

青霉素-链霉素-两性霉素B三抗溶液(100×),灭菌

Solution in bottle

TargetMol 试剂盒

青霉素-链霉素-两性霉素B三抗溶液(100×),灭菌
Cat.No: C0052
Cat. No. Product Name Target Signaling Pathways
T8851 I3MT-3

HMPSNE

Hippo pathway Stem Cells
I3MT-3 (HMPSNE) 是一种有效的、具有细胞膜渗透性的、选择性的 3-巯基丙酮酸硫转移酶 (3MST)的抑制剂,IC50值为2.7 μM,对其他硫化氢/磺胺制硫酶没有活性。它靶向位于 3MST 活性位点的过硫半胱氨酸残基。
T10952 Dabuzalgron

达布扎琼,Ro 115-1240

Apoptosis; Adrenergic Receptor Apoptosis; GPCR/G Protein; Neuroscience
Dabuzalgron (Ro 115-1240) 是一种口服活性选择性 α-1A 肾上腺素受体激动剂,用于治疗尿失禁。它通过维持线粒体功能来预防多柔比星引起的心脏毒性。
T5827 BI-6C9

Apoptosis; Others; Mitochondrial Metabolism Apoptosis; Metabolism; Others
BI-6C9 是一种高特异性的 BH3 相互作用结构域抑制剂,可阻止线粒体外膜电位和线粒体分裂,并保护细胞免受线粒体凋亡诱导因子释放和不依赖 caspase 的细胞死亡。
T1000L Chlorhexidine diacetate

醋酸氯己定,Hibitane diacetate,Chlorhexidine Acetate,Bactigras

CAT; Antibacterial; Antibiotic; Antifection Microbiology/Virology; oxidation-reduction
Chlorhexidine diacetate (Bactigras) 是一种双胍类杀菌剂,能快速消灭革兰氏阳性菌和革兰氏阴性菌。它也用作漱口水以防止口腔菌斑。
T6658 SB-408124

N-(6,8-二氟-2-甲基-4-喹啉)- N-[4-(二甲氨基)苯基]尿素

OX Receptor GPCR/G Protein; Neuroscience
SB408124 是一种 OX1 受体的非肽拮抗剂,在全细胞和膜中的 Ki 值分别为 57 和 27 nM,其选择性是 OX2 受体的 50 倍。
T20843 Aplodan

Nergize,Creatinolfosfate,磷酸肌肉醇,creatinol-O-phosphate,Creatinolfosfate, Creatinol Phosphate

Others Others
Aplodan (creatinol-O-phosphate) 表现出抗缺血和抗心律失常的能力以及对细胞膜的保护作用。 Aplodan 可用于缺血性心脏病或伴有持续性室性早搏的缺血性心脏病的研究。
T6063 LY-411575

LY411575

Apoptosis; Gamma-secretase Apoptosis; Neuroscience; Proteases/Proteasome; Stem Cells
LY-411575 是一种高效的γ-secretase 抑制剂,能够抑制 Aβ40 蛋白的产生,在膜中的 IC50 为 0.078 nM,在细胞中为 0.082 nM。 它还抑制 Notch 切割,IC50 为 0.39 nM。
T1497 Liranaftate

Piritetrate,利拉萘酯,M-732

Antifungal Microbiology/Virology
Liranaftate (Piritetrate) 是一种具有抗真菌活性的硫代氨基甲酸酯和角鲨烯环氧酶抑制剂,可研究皮肤癣菌。
T1290 Oxiconazole nitrate

硝酸奥昔康唑,Ro 13-8996

Others; Antibiotic; Antifection; Antifungal Microbiology/Virology; Others
Oxiconazole nitrate (Ro 13-8996) 是广谱抗真菌药物,抑制T. tonsurans 和T.rubrum 的生长,MIC90值分别为 0.25 和 0.5 μg/mL。
T3934 Isavuconazonium sulfate

Antifungal Microbiology/Virology
Isavuconazonium sulfate 是一种口服活性抗真菌药,是活性三唑类抗真菌药物 Isavuconazole 的前药,可用于侵袭性曲霉菌病和毛霉菌病。
T1187 Bifonazole

联苯苄唑,Bay H-4502

P450; Antibiotic; Antifungal Metabolism; Microbiology/Virology
Bifonazole (Bay H-4502) 是咪唑类抗真菌剂。
T20642 Laurdan

6-十二酰基-N,N-二甲基-2-萘胺,6-Dodecanoyl-2-dimethylaminonaphthalene

Others Others
Laurdan (6-Dodecanoyl-2-dimethylaminonaphthalene) 是膜透性荧光探针。它的广义极化 (GP) 定量可用于磷脂相的鉴定,对与之结合的细胞膜磷脂相具有光谱敏感性。
T1005L Amoxicillin trihydrate

Amoxycillin trihydrate,Amoxil trihydrate,Amoxipen trihydrate,阿莫西林三水物,Moxaline trihydrate

Antibacterial; Antibiotic Microbiology/Virology
Amoxicillin trihydrate (Moxaline trihydrate) 是一种中谱β内酰胺抗菌素。
T15660 KHK-IN-1

KHK-IN-8,Ketohexokinase inhibitor 8

Others Others
KHK-IN-1 (KHK-IN-8) 是一种选择性的、细胞膜渗透性的己酮糖激酶 (KHK) 抑制剂 (IC50=12 nM; F=34%)。KHK-IN-1 抑制 HepG2 细胞裂解液中 F1P 生成,IC50为400 nM。KHK-IN-1 可用于研究糖尿病和肥胖症。
T6686 Sulconazole mononitrate

Exelderm,Sulconazole Nitrate,RS 44872,硝酸硫康唑

Antibacterial; Antibiotic; Antifungal Microbiology/Virology
Sulconazole mononitrate (Exelderm) 是一种咪唑类广谱杀菌剂。它可研究皮肤真菌病,花斑糠疹病,皮肤念珠菌病。
T12470 Picloxydine

Antibacterial Microbiology/Virology
Picloxydine 是一种杂环双胍,有抗细菌和牙菌斑活性。
T10601 BRCA1-IN-2

Others Others
BRCA1-IN-2 是一种可穿过细胞膜的 BRCA1 蛋白-蛋白相互作用(PPI)抑制剂,具有抗肿瘤活性,通过破坏 BRCA1 (BRCT)2 与蛋白质的相互作用来发挥作用。
T2661 TGX-221

TGX221

PI3K PI3K/Akt/mTOR signaling
TGX-221 是一种选择性的、高效的、细胞膜渗透的 PI3K p110β 抑制剂,常用于研究癌症。
T6437 Cefoperazone

头孢哌酮,Cefob,Medocef

Antibacterial; Antibiotic Microbiology/Virology
Cefoperazone (Medocef) 是一种半合成的头孢菌素,有抗菌活性。
T16798 RS 17053 hydrochloride

RS-17053

Others; Adrenergic Receptor GPCR/G Protein; Neuroscience; Others
RS 17053 hydrochloride 是有效的、选择性的 α1A 肾上腺素受体 (α1A adrenoceptor) 拮抗剂。RS 17053 hydrochloride 在细胞膜中测得的 pKi 值为 9.1,功能分析的 pA2 值为 9.8。
T17065 TFMB-(R)-2-HG

Others Others
TFMB-(R)-2-HG 是一种具有细胞膜渗透性的 (R)-2-HG,急性髓细胞性白血病的致癌因子。它能够响应雌激素戒断损害SCF ER-Hoxb8 细胞分化。
T2213 Terconazole

Gyno-Terazol,Terazol 3,Terazol 7,Triaconazole,特康唑,曲康唑,R42470

Antifection; Antifungal Microbiology/Virology
Terconazole (Terazol 7) 是一种广谱抗真菌药物,用于研究阴道酵母菌感染。
T77478 Milatuzumab

hLL1,MEDI-115

Others Others
Milatuzumab (MEDI-115) 是一种人源化抗 CD74 单克隆抗体。Milatuzumab 促使自由基氧的产生和线粒体膜电位的丧失,可降低 CD20/CD74 聚集体和细胞粘附,诱导细胞死亡。
T7866 Difenoconazole

Others; Antifungal Microbiology/Virology; Others
Difenoconazole 是一种广谱三唑类杀菌剂,通过抑制羊毛甾醇的细胞色素 P450 依赖性 14α-去甲基化来抑制麦角甾醇的生物合成,从而导致真菌细胞膜的破坏和细胞死亡。
T1228 Cefonicid sodium

Monocid sodium,头孢尼西钠,Cefonicid disodium salt

Antibacterial; Antibiotic Microbiology/Virology
Cefonicid sodium (Monocid sodium) 是一种广谱头孢类抗生素, 能抑制细菌细胞壁的形成。
T39027 PKH 26

PKH26,PKH-26

PKH 26 是一种有红荧光的膜染料,Ex/Em=551/567 nm。PKH 26 常用于流式细胞术,可测定 T 细胞介导的细胞毒性活性。
T1000 Chlorhexidine

氯己定,Chlorhexidinum,Nolvasan,Rotersept

CAT; Antibacterial; Antibiotic; Antifection Microbiology/Virology; oxidation-reduction
Chlorhexidine (Rotersept) 是一种抗菌剂和防腐剂。它可用于注射前、手术前或外伤后清洁皮肤。
T21992 Vacuolin-1

PI3K; Autophagy Autophagy; PI3K/Akt/mTOR signaling
Vacuolin-1 是一种细胞渗透性抑制剂,可抑制 Ca2+ 依赖性溶酶体与细胞膜的融合。它通过抑制溶酶体内容物的释放起作用。它是一种有效的选择性 PIKfyve 抑制剂,通过损害溶酶体成熟来抑制晚期自噬。
T1005 Amoxicillin

Amoxycillin,阿莫西林

Antibacterial; Antibiotic Microbiology/Virology
Amoxicillin (Amoxycillin) 是一种具有广谱抗菌活性和良好口服吸收的抗生素。
T18894 5(6)-CFDA

CFDA,5-(6)-Carboxyfluorescein diacetate,5(6)-羧基荧光素二乙酸酯

Others Others
5(6)-CFDA (5-(6)-Carboxyfluorescein diacetate) 是具有细胞渗透性的胺反应型绿色荧光探针(λex: 492 nm; λem: 517 nm),可用于细胞染色分析。
T5966 Hexaconazole

己唑醇,(-)-Hexaconazol

Reactive Oxygen Species; Antifungal Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
Hexaconazole ((-)-Hexaconazol) 是一种广谱三唑类杀菌剂,通过抑制羊毛甾醇的细胞色素 P450 依赖性 14α-去甲基化来抑制麦角甾醇的生物合成,从而导致真菌细胞膜的破坏和细胞死亡。
T15458 H2DCFDA

2',7'-二氯荧光素二乙酸酯,2',7'-Dichlorodihydrofluorescein diacetate,DCFH-DA

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
H2DCFDA (DCFH-DA) 属于绿色荧光染料,是一种检测细胞内活性氧 (ROS) 的探针 (Ex/Em=488/525 nm),具有细胞膜渗透性。
T84368 Caldaret HCl

MCC-135 HCl,Caldaret HCl(192509-24-3 Free base)

Calcium Channel Membrane transporter/Ion channel; Metabolism
Caldaret HCl 是一种细胞内 Ca2+ 调节剂,可调节肌浆网和细胞膜处的钙稳态,可用于研究急性心肌梗死和心力衰竭。
T1213 Piperacillin sodium

哌拉西林钠,Sodium piperacillin,CL227193,Piperacillin sodium salt

Antibacterial; Antibiotic Microbiology/Virology
Piperacillin sodium salt(CL227193) )是一种β-内酰胺类广谱抗生素。
T0104 Umifenovir hydrochloride

盐酸阿比朵尔,Arbidol hydrochloride,Arbidol HCl,盐酸阿比多尔

SARS-CoV; Influenza Virus Microbiology/Virology
Umifenovir hydrochloride (Arbidol HCl) 是一种口服有效的广谱抗病毒药物,对多种包膜和非包膜病毒均有活性。它被用作抗流感病毒剂,可通过阻断病毒与宿主细胞膜的融合来抑制包膜病毒的细胞侵袭。它是一种 SARS-CoV-2 抑制剂,具有抗炎活性。
T0953 Cefazolin sodium

Ancef,头孢唑啉钠,头孢唑林钠,Cefazolin sodium salt,Sodium cephazolin,cephazolin sodium,cefazoline sodium,Sodium cefazolin

Others; Antibacterial; Antibiotic Microbiology/Virology; Others
Cefazolin sodium (cephazolin sodium) salt 是一种头孢类抗生素, 可研究多种细菌感染。
T0187 Amorolfine hydrochloride

Amorolfin,盐酸阿莫洛芬,Amorolfine HCl,盐酸阿莫罗芬,Ro 14-4767/002

Antibiotic; Antifungal Microbiology/Virology
Amorolfine hydrochloride (Amorolfine HCl) 是一种抗真菌剂。
T78392 Zinquin ethyl ester

Zinquin ethyl ester是可穿透细胞膜且具有选择性的锌离子荧光探针,可测量Zn(2+)和Ca(2+)离子的细胞内水平,可对早期胚胎进行染色。
T6802 CFSE

5(6)-CFDA N-succinmidyl ester,Carboxyfluorescein succinimidyl ester,CFDA-SE,5(6)-羧基二乙酸荧光素琥珀酰亚胺酯,5(6)-Carboxyfluorescein diacetate succinimidyl ester

Others Others
CFSE (CFDA-SE) 属于荧光染料,具有细胞膜渗透性。CFSE 可在活细胞内与胞内蛋白进行不可逆的结合,用于检测细胞增殖,标记的细胞呈绿色荧光,激发波长为 488 nm,发射波长为 518 nm。
T8886 NITD-2

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
NITD-2 是一种登革病毒 (DENV) 聚合酶抑制剂,可抑制 DENV RdRp 介导的 RNA 延伸。
T1122 Cephalothin sodium

头孢噻吩钠,Cefalotin sodium,Cephalothin,Cefalotin

Antibacterial; Antibiotic Microbiology/Virology
Cephalothin sodium (Cefalotin) 是一种头孢类抗生素, 具有广泛的抗菌活性,抑制革兰氏阳性和阴性菌。
T8644 Elamipretide Triacetate

Elamipretide TriTFA

Others Others
Elamipretide Triacetate (Elamipretide TriTFA) 是一种芳香族阳离子四肽,可轻松穿透细胞膜并短暂定位于线粒体内膜,在此与心磷脂结合。它已用于研究 Leber 遗传性视神经病变治疗的试验。
T6929 Pantoprazole sodium

Pantecta,泮托拉唑钠盐,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),泮托拉唑钠,BY-1023 sodium,Pantoloc

Apoptosis; Others; Proton pump; HIF; Autophagy Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; Membrane transporter/Ion channel; Others
Pantoprazole sodium (Pantecta) 是一种具有口服活性的质子泵抑制剂,是一种取代的苯并咪唑,是H+/K+-ATPase 抑制剂,IC50为 6.8 μM。它可以改善 pH 值稳定性,具有抗分泌和抗溃疡的作用。它联合阿霉素可显著增加肿瘤生长延迟。
T1438 Butoconazole nitrate

RS 35887,硝酸布康唑

Estrogen/progestogen Receptor; Antifungal Endocrinology/Hormones; Microbiology/Virology
Butoconazole nitrate (RS 35887) 是一种咪唑类抗真菌药物,可治疗由白色念珠菌引起的阴道感染。它可通过抑制类固醇合成起到抗菌作用。
T2606 KN-93 Phosphate

CaMK Neuroscience
KN-93可以竞争性阻断钙调蛋白与对应激酶的结合,是一种钙离子/钙调蛋白依赖激酶 II(CaMKII)抑制剂,Ki 为370 nM。
TP1484L α2β1 Integrin Ligand Peptide acetate

α2β1 Integrin Ligand Peptide acetate (134580-64-6)

Integrin Cytoskeletal Signaling
α2β1 Integrin Ligand Peptide acetate (α2β1 Integrin Ligand Peptide acetate (134580-64-6)) 是 α2β1 整合素受体的潜在拮抗剂。它与细胞膜上的 α2β1 整合素受体相互作用,介导细胞外信号进入细胞。
T15176 DSS Crosslinker

Others; ADC Linker Antibody-drug Conjugate/ADC Related; Others
DSS Crosslinker 是一种不可切割的 ADC 连接剂,用于合成抗体-药物偶联物。
T22361 Mepivacaine

Carbocaine

Sodium Channel Membrane transporter/Ion channel
Mepivacaine (Carbocaine) 是一种可用于局部麻醉的酰胺类化合物,可使人或动物短暂的失去自知觉。Mepivacaine 通过与神经细胞膜上特定的电压门控钠离子通道结合,抑制钠离子内流和膜去极化来发挥作用。Mepivacaine 适用于神经阻滞和硬膜外麻醉。
T1627 Famotidine

MK-208,法莫替丁

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Famotidine (MK-208) 是一种具有抗酸活性的丙脒和组胺 H2 受体拮抗剂。
T15129 DiI

DiIC18(3)

Others Others
DiI (DiIC18(3)) 是一种亲脂性膜染料,通常用作神经元和其它细胞的长期示踪剂。它在进入细胞膜之前荧光非常弱,仅当进入到细胞膜后才可以被激发出很强的橙红色荧光 (λex=549 nm,λem=565 nm)。

化合物

I3MT-3
Cat.No: T8851
Synonym: HMPSNE
Target: Hippo pathway
Dabuzalgron
Cat.No: T10952
Synonym: 达布扎琼,Ro 115-1240
Target: Apoptosis, Adrenergic Receptor
BI-6C9
Cat.No: T5827
Synonym:
Target: Apoptosis, Others, Mitochondrial Metabolism
Chlorhexidine diacetate
Cat.No: T1000L
Synonym: 醋酸氯己定,Hibitane diacetate,Chlorhexidine Acetate,Bactigras
Target: CAT, Antibacterial, Antibiotic, Antifection
SB-408124
Cat.No: T6658
Synonym: N-(6,8-二氟-2-甲基-4-喹啉)- N-[4-(二甲氨基)苯基]尿素
Target: OX Receptor
Aplodan
Cat.No: T20843
Synonym: Nergize,Creatinolfosfate,磷酸肌肉醇,creatinol-O-phosphate,Creatinolfosfate, Creatinol Phosphate
Target: Others
LY-411575
Cat.No: T6063
Synonym: LY411575
Target: Apoptosis, Gamma-secretase
Liranaftate
Cat.No: T1497
Synonym: Piritetrate,利拉萘酯,M-732
Target: Antifungal
Oxiconazole nitrate
Cat.No: T1290
Synonym: 硝酸奥昔康唑,Ro 13-8996
Target: Others, Antibiotic, Antifection, Antifungal
Isavuconazonium sulfate
Cat.No: T3934
Synonym:
Target: Antifungal
Bifonazole
Cat.No: T1187
Synonym: 联苯苄唑,Bay H-4502
Target: P450, Antibiotic, Antifungal
Laurdan
Cat.No: T20642
Synonym: 6-十二酰基-N,N-二甲基-2-萘胺,6-Dodecanoyl-2-dimethylaminonaphthalene
Target: Others
Amoxicillin trihydrate
Cat.No: T1005L
Synonym: Amoxycillin trihydrate,Amoxil trihydrate,Amoxipen trihydrate,阿莫西林三水物,Moxaline trihydrate
Target: Antibacterial, Antibiotic
KHK-IN-1
Cat.No: T15660
Synonym: KHK-IN-8,Ketohexokinase inhibitor 8
Target: Others
Sulconazole mononitrate
Cat.No: T6686
Synonym: Exelderm,Sulconazole Nitrate,RS 44872,硝酸硫康唑
Target: Antibacterial, Antibiotic, Antifungal
Picloxydine
Cat.No: T12470
Synonym:
Target: Antibacterial
BRCA1-IN-2
Cat.No: T10601
Synonym:
Target: Others
TGX-221
Cat.No: T2661
Synonym: TGX221
Target: PI3K
Cefoperazone
Cat.No: T6437
Synonym: 头孢哌酮,Cefob,Medocef
Target: Antibacterial, Antibiotic
RS 17053 hydrochloride
Cat.No: T16798
Synonym: RS-17053
Target: Others, Adrenergic Receptor
TFMB-(R)-2-HG
Cat.No: T17065
Synonym:
Target: Others
Terconazole
Cat.No: T2213
Synonym: Gyno-Terazol,Terazol 3,Terazol 7,Triaconazole,特康唑,曲康唑,R42470
Target: Antifection, Antifungal
Milatuzumab
Cat.No: T77478
Synonym: hLL1,MEDI-115
Target: Others
Difenoconazole
Cat.No: T7866
Synonym:
Target: Others, Antifungal
Cefonicid sodium
Cat.No: T1228
Synonym: Monocid sodium,头孢尼西钠,Cefonicid disodium salt
Target: Antibacterial, Antibiotic
PKH 26
Cat.No: T39027
Synonym: PKH26,PKH-26
Target:
Chlorhexidine
Cat.No: T1000
Synonym: 氯己定,Chlorhexidinum,Nolvasan,Rotersept
Target: CAT, Antibacterial, Antibiotic, Antifection
Vacuolin-1
Cat.No: T21992
Synonym:
Target: PI3K, Autophagy
Amoxicillin
Cat.No: T1005
Synonym: Amoxycillin,阿莫西林
Target: Antibacterial, Antibiotic
5(6)-CFDA
Cat.No: T18894
Synonym: CFDA,5-(6)-Carboxyfluorescein diacetate,5(6)-羧基荧光素二乙酸酯
Target: Others
Hexaconazole
Cat.No: T5966
Synonym: 己唑醇,(-)-Hexaconazol
Target: Reactive Oxygen Species, Antifungal
H2DCFDA
Cat.No: T15458
Synonym: 2',7'-二氯荧光素二乙酸酯,2',7'-Dichlorodihydrofluorescein diacetate,DCFH-DA
Target: Reactive Oxygen Species
Caldaret HCl
Cat.No: T84368
Synonym: MCC-135 HCl,Caldaret HCl(192509-24-3 Free base)
Target: Calcium Channel
Piperacillin sodium
Cat.No: T1213
Synonym: 哌拉西林钠,Sodium piperacillin,CL227193,Piperacillin sodium salt
Target: Antibacterial, Antibiotic
Umifenovir hydrochloride
Cat.No: T0104
Synonym: 盐酸阿比朵尔,Arbidol hydrochloride,Arbidol HCl,盐酸阿比多尔
Target: SARS-CoV, Influenza Virus
Cefazolin sodium
Cat.No: T0953
Synonym: Ancef,头孢唑啉钠,头孢唑林钠,Cefazolin sodium salt,Sodium cephazolin,cephazolin sodium,cefazoline sodium,Sodium cefazolin
Target: Others, Antibacterial, Antibiotic
Amorolfine hydrochloride
Cat.No: T0187
Synonym: Amorolfin,盐酸阿莫洛芬,Amorolfine HCl,盐酸阿莫罗芬,Ro 14-4767/002
Target: Antibiotic, Antifungal
Zinquin ethyl ester
Cat.No: T78392
Synonym:
Target:
CFSE
Cat.No: T6802
Synonym: 5(6)-CFDA N-succinmidyl ester,Carboxyfluorescein succinimidyl ester,CFDA-SE,5(6)-羧基二乙酸荧光素琥珀酰亚胺酯,5(6)-Carboxyfluorescein diacetate succinimidyl ester
Target: Others
NITD-2
Cat.No: T8886
Synonym:
Target: DNA/RNA Synthesis
Cephalothin sodium
Cat.No: T1122
Synonym: 头孢噻吩钠,Cefalotin sodium,Cephalothin,Cefalotin
Target: Antibacterial, Antibiotic
Elamipretide Triacetate
Cat.No: T8644
Synonym: Elamipretide TriTFA
Target: Others
Pantoprazole sodium
Cat.No: T6929
Synonym: Pantecta,泮托拉唑钠盐,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),泮托拉唑钠,BY-1023 sodium,Pantoloc
Target: Apoptosis, Others, Proton pump, HIF, Autophagy
Butoconazole nitrate
Cat.No: T1438
Synonym: RS 35887,硝酸布康唑
Target: Estrogen/progestogen Receptor, Antifungal
KN-93 Phosphate
Cat.No: T2606
Synonym:
Target: CaMK
α2β1 Integrin Ligand Peptide acetate
Cat.No: TP1484L
Synonym: α2β1 Integrin Ligand Peptide acetate (134580-64-6)
Target: Integrin
DSS Crosslinker
Cat.No: T15176
Synonym:
Target: Others, ADC Linker
Mepivacaine
Cat.No: T22361
Synonym: Carbocaine
Target: Sodium Channel
Famotidine
Cat.No: T1627
Synonym: MK-208,法莫替丁
Target: Histamine Receptor
DiI
Cat.No: T15129
Synonym: DiIC18(3)
Target: Others
Cat. No. Product Name Target Signaling Pathways
T21164 Sulfentrazone

甲磺草胺,FP-846

Others Others
Sulfentrazone (FP-846) 是苯基三唑啉酮除草剂,能够抑制原卟啉原氧化酶,导致脂质细胞膜破裂,可用于控制某些阔叶和禾本科杂草。
T5080 Spermidine trihydrochloride

Spermidine hydrochloride,4-Azaoctamethylenediamine trihydrochloride,三盐酸亚精胺,亚精胺盐酸盐

NMDAR; Autophagy Autophagy; Neuroscience
Spermidine trihydrochloride (4-Azaoctamethylenediamine trihydrochloride) 能够维持细胞膜稳定性,提高抗氧化酶特性,改善光系统 II (PSII) 以及相关基因表达,也能够显著抑制 H2O2和 O2.-含量。
T4893 Spermidine

N-(3-Aminopropyl)-1,4-diaminobutane,亚精胺,N-(4-Aminobutyl)-1,3-diaminopropane

Endogenous Metabolite Metabolism
Spermidine (N-(3-Aminopropyl)-1,4-diaminobutane) 属于天然多胺,存在于核糖体和活组织中,在生物体内具有各种代谢功能。Spermidine 具有炎症减轻、调节脂质代谢、调节细胞生长和死亡的功能。
T5239 Cholesteryl sulfate sodium

Cholesterol 3-Sulfate Sodium Salt,胆固醇硫酸酯钠盐,Sodium Cholesteryl Sulfate

Endogenous Metabolite; PKC Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism
Cholesteryl sulfate sodium (Sodium Cholesteryl Sulfate) 是内源性代谢产物的一种。
TF0083 POPE

POPE 是从大肠杆菌中发现的化合物,是细胞膜的一部分,可用来研究改变细胞膜通透性。
T2905 5α-Cholestan-3-one

5-Α-胆甾烷-3-酮,Coprostanone,5alpha-Cholestan-3-one

Others; Endogenous Metabolite Metabolism; Others
5α-Cholestan-3-one (Coprostanone) 是内源性代谢产物的一种。
TN6912 1-Nonanol

Nonan-1-ol

Antifungal Microbiology/Virology
1-Nonanol (Nonan-1-ol) 是一种香料,具有抗真菌活性,通过破坏细胞膜的完整性和线粒体功能发挥作用。
T0146 Tioconazole

UK-20349,Vagistat,噻康唑

Antibiotic; Antifection; Antifungal Microbiology/Virology
Tioconazole (Vagistat) 是一种广谱性的抗真菌咪唑衍生物。它抑制几种皮肤真菌和几种酵母菌的 MIC50分别小于 3.12 mg/L 和 9 mg/L。
T3237 Lecithin

Phospholutein,卵磷脂,L-α-磷脂酰胆碱,L-α-Phosphatidylcholine,Phosphatidylcholines

Others; Endogenous Metabolite Metabolism; Others
Lecithin (L-α-Phosphatidylcholine) 被认为是安全的常规磷脂源。磷脂能够改变动物细胞膜的脂肪酸组成和微观结构。
T4889 2,6-Diaminoheptanedioic acid

Others; Endogenous Metabolite Metabolism; Others
2,6-Diaminoheptanedioic acid 是内源性代谢产物的一种。
T6702 Terbinafine

Terbinex,特比萘芬,SF 86-327,Lamisil,TDT 067

Antibacterial; Antibiotic; Antifungal Microbiology/Virology
Terbinafine (TDT 067) 是念珠菌属的角鲨烯环氧化酶有效的非竞争性抑制剂,Ki 值为 30 nM。它具有抗真菌感染活性。
T12451 PEP 3CHA

PEP 3 CHA,Phosphoenolpyruvic acid tricyclohexylammonium salt,磷酸烯醇丙酮酸三(环已胺)盐

Others Others
Phosphoenolpyruvic acid tricyclohexylammoniu​m salt (PEP 3 CHA) 是一种能够透过细胞膜的糖酵解代谢物,含有高能磷酸基团,具有细胞保护和抗氧化作用。
T2P2806 Hederacolchiside A1

黑海常春藤苷A1,革叶常春藤皂苷 A1,Raddeanoside R13

Apoptosis; ERK; MEK; Akt; PI3K; Parasite; mTOR Apoptosis; Cytoskeletal Signaling; MAPK; Microbiology/Virology; PI3K/Akt/mTOR signaling
Hederacolchiside A1 (Raddeanoside R13) 是从白头翁中分离的一种有抗利什曼原虫和抗肿瘤增殖活性的天然产物。
T21437 DSPS

DSPS (From soybeans),Phosphatidylserine(36:0),磷脂酰丝氨酸,Dioctadecanoylphosphatidylserine,Distearoyl phosphatidylserine

Others Others
DSPS (Dioctadecanoylphosphatidylserine) 是一种甘油磷脂,是重要的磷脂膜成分,在细胞周期信号传导中起关键作用。DSPS 可以调节细胞活性,介导细胞凋亡。DSPS 被广泛用作营养补充剂。
TN1624 Ethyl cinnamate

Calcium Channel; ROS; NO Synthase Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism
Ethyl cinnamate 是食品香料和化妆品添加剂,也是哺乳动物组织的优良清除剂。
T6564 Leupeptin Hemisulfate

亮肽素

Serine Protease; Cysteine Protease Proteases/Proteasome
Leupeptin hemisulfate 是一种蛋白酶抑制剂,具有细胞膜渗透性、可逆性、竞争性和口服活性。Leupeptin hemisulfate 可以抑制 Cathepsin B、Cathepsin H、Cathepsin L 的活性,阻断两性溶酶体的融合。Leupeptin hemisulfate 还具有抗炎活性。
TN2160 Roemerine

(-)-Roemerine

Antibiotic Microbiology/Virology
Roemerine ((-)-Roemerine) 是一种来自塞内加尔番荔枝的卟啉生物碱,具有抗真菌和抗癌活性,通过抑制 Bmr 来防止小檗碱外排。Roemerine 以浓度依赖性方式增加细胞膜通透性,可用于研究真菌感染和前列腺癌。
T3426 Bacoside A

MMP; Others; TNF; Dopamine Receptor; NOS; ROS Apoptosis; GPCR/G Protein; Immunology/Inflammation; Neuroscience; Others; Proteases/Proteasome
Bacoside A has a possible anticancer activity that could be inducing cell cycle arrest and apoptosis through Notch pathway in GBM in vitro. It exerts cytoprotective efficacy by attenuation of ROS generated through oxidative stress by an increase in the concentration of antioxidant enzymes and sustain membrane integrity which leads to restoring the damage caused by tBHP. Bacoside A can able to inhibit the progression of Experimental Autoimmune Encephalomyelitis (EAE) may be by the inhibition of i...
T0034 Cortisone acetate

醋酸可的松,Cortisone 21-acetate,NSC 49420

Glucocorticoid Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism
Cortisone acetate (NSC-49420) 是 Cortisol(一种糖皮质激素)的氧化代谢产物。它在高浓度下能够部分干预 Glucocorticoid 与Glucocorticoid-receptor 的结合。它具有免疫抑制和消炎的作用。
T38141 Glycerophospholipids, cephalins

Phosphatidylethanolamines (egg)

Glycerophospholipids, cephalins (Phosphatidylethanolamines (egg)) 是一种从鸡蛋中分离出来的磷脂酰乙醇胺的混合物,在 sn-1和 sn-2位置有各种脂肪酰基。Glycerophospholipids, cephalins 完全水解可得到1mol 的甘油、磷酸、乙醇胺和2mol 的脂肪酸。Phosphatidylethanolamines 在膜融合和细胞分裂过程中收缩环的拆卸中起作用,可调节膜的弯曲度。Phosphatidylethanolamines 能够在没有任何蛋白质或核酸的帮助下传播传染性朊病毒。Phosphatidylethanolamines 在细菌膜中的主要作用之一是分散由阴离子膜磷脂引起的负电荷。
TN6872 Trypsin

Protease-activated Receptor GPCR/G Protein
Trypsin 是一种可从鱼类分离出的丝氨酸蛋白酶,可水解赖氨酸或精氨酸羧基侧蛋白质。Trypsin 具有抗炎活性,可通过 PDCoV 的 S 糖蛋白与 pAPN 的相互作用诱导 PDCoV 感染的细胞膜融合,可激活 PAR2 和 PAR4,促进细胞增殖和分化。Trypsin 可用于促进伤口愈合和研究神经源性炎症。
T11855 Lipopolysaccharides

脂多糖,LPS

Others Others
Lipopolysaccharides (LPS) 是革兰氏阴性细菌细胞壁的一种特有成分,由脂质A、寡糖核心和 O -特异性多糖 (O-antigen) 3个区域组成。Lipopolysaccharides 有利于维持细胞外膜的完整性,保护细菌免受胆汁盐和脂类抗生素的破坏。Lipopolysaccharides 是一种高免疫原性抗原,可以增强免疫反应,可以用于炎症模型构建。
T3388 Calycosin-7-O-β-D-glucoside

毛蕊异黄酮苷,calycosin-7-O-beta-D-glucopyranoside,Calycosin-7-O-beta-D-glucoside

MMP; Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB; Proteases/Proteasome
Calycosin-7-O-β-D-glucoside (calycosin-7-O-beta-D-glucopyranoside) 是一种异黄酮,从黄芪中分离得到。它具有多种生物活性,包括心脏保护、神经保护、抗炎和抗氧化作用。
T41078 Lipopolysaccharides, Escherichiacoli

Lipopolysaccharide, E. coli O111:B4

Others Others
Lipopolysaccharides, Escherichiacoli (E. coli O111:B4) 是革兰氏阴性细菌细胞壁的一种特有成分,由脂质A、寡糖核心和 O -特异性多糖 (O-antigen) 3个区域组成。Lipopolysaccharides, Escherichiacoli 有利于维持细胞外膜的完整性,保护细菌免受胆汁盐和脂类抗生素的破坏。Lipopolysaccharides, Escherichiacoli 是一种高免疫原性抗原,可以增强免疫反应,可以用于炎症模型构建。
T5004 Hyaluronic acid sodium

透明质酸钠,Sodium Hyaluronate

Others Others
Hyaluronic acid sodium (Sodium Hyaluronate) 是一种生物聚合物,由二糖的重复单元组成,应用领域广泛。
T2S2362 Dehydrocorydaline nitrate

去氢延胡索甲素硝酸盐,硝酸脱氢紫堇碱

BCL; Others; PARP; p38 MAPK; Caspase; Parasite; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; MAPK; Microbiology/Virology; Others; Proteases/Proteasome
Dehydrocorydaline nitrate 是生物碱。Dehydrocorydaline 调节 Bax,Bcl-2蛋白表达,激活 caspase-7,caspase-8,并使 PARP 失活。它能增强 p38 MAPK 活化,具有抗炎、抗癌、抗疟疾等功效。
T0798 Triamcinolone

Fluoxyprednisolone,曲安西龙,Aristocort,Rodinolone

Glucocorticoid Receptor; COX Endocrinology/Hormones; Immunology/Inflammation; Neuroscience
Triamcinolone (Aristocort) 是一种皮质类固醇激素受体激动剂,也是一种合成的长效糖皮质激素,具有抗炎活性。
T4855 Tricosanoic acid

Tricosan-1-oic acid,二十三烷酸

Endogenous Metabolite Metabolism
Tricosanoic acid (Tricosan-1-oic acid) 是毛发生长激活剂,是长链脂肪酸。
T4881 Phosphorylethanolamine

O-Phosphorylethanolamine,乙醇胺磷酸酯

Others; Endogenous Metabolite Metabolism; Others
Phosphorylethanolamine (O-Phosphorylethanolamine) 是磷脂代谢的一种磷酸单酯代谢物。Phosphorylethanolamine 是磷脂合成的前体,也是磷脂分解的产物。与其他器官相比,大脑中磷酸单酯的含量要高得多。在大脑发育过程中,磷单酯通常在神经增生期间升高。这也与大脑发育过程中正常的程序性细胞死亡和突触修剪的发生相吻合。这些发现与磷酸单酯在膜生物合成中的作用是一致的。Phosphorylethanolamine 与抑制性神经递质GABA和GABAB受体部分激动剂 3-氨基丙基膦酸具有很强的结构相似性。Phosphorylethanolamine 是一种磷单酯,在阿尔茨海默病患者的大脑中减少。
T37876 Fengycin

Others Others
Fengycin is a cyclic lipopeptide used as an agricultural fungicide. Fengmycin has an anti-fungal infection effect by damaging the target’s cell membrane[1]. [1]. Sreyoshi Sur, et al. Selectivity and Mechanism of Fengycin, an Antimicrobial Lipopeptide, from Molecular Dynamics. J Phys Chem B. 2018 Mar 1;122(8):2219-2226.
TN4435 Licopyranocoumarin

P450; ROS; JNK Immunology/Inflammation; MAPK; Metabolism
Licopyranocoumarin could as a potent neuroprotective drug via markedly blocked MPP+-induced neuronal PC12D cell death and disappearance of mitochondrial membrane potential, which were mediated by JNK.
T40600 Iturin A

Others Others
Iturin A is a chemical compound with potent antifungal properties against pathogenic yeast and fungi. It interacts with the cytoplasmic membrane of the target cell, leading to the formation of ion conducting pores.
T15637 K-252b

PKC Chromatin/Epigenetic; Cytoskeletal Signaling
K-252b is an indolocarbazole isolated from the actinomycete Nocardiopsis and is a PKC inhibitor. K-252b can be used to inhibit extracellular kinases of cells in culture because it can’t pass through the cell membrane freely.
T73808 Zymosterol

Others Others
Zymosterol 是一种胆固醇Cholesterol 生物合成代谢物。Zymosterol 是胆固醇的前体,主要存在于质膜中。Zymosterol 在细胞内循环。
TN7555 Aspochracin

Aspochracin

Others Others
Aspochracin, a biochemical compound, exhibits potent antifungal activity by inhibiting the growth of various fungal species. This secondary metabolite, produced by Aspergillus spp., plays a crucial role in pharmaceutical applications, particularly in the development of antifungal agents. Its chemical structure enables the interference with the cell membrane of fungi, leading to disruption of essential biological processes and ultimately, fungal cell death.
T79982 2'-epi-2'-O-Acetylthevetin B

GHSC-74

Apoptosis Apoptosis
2'-epi-2'-O-Acetylthevetin B (GHSC-74) 为源自Cerbera manghas L种子的强心苷,其抑制HepG2细胞增殖并诱导细胞凋亡(apoptosis)及线粒体膜电位降低。
TN2445 Kuwanon B

Others Others
Kuwanon B belongs to the class of organic compounds known as 3-prenylated flavones. Within the cell, kuwanon B is primarily located in the membrane (predicted from logP). Outside of the human body, kuwanon b can be found in fruits. This makes kuwanon b a
T35577 Phosphatidylserines (bovine)

Others Others
Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on the inner leaflet of the cell membrane. It is biosynthesized from phosphatidylcholine or phosphatidylethanolamine by phosphatidyl synthase 1 (PSS1) or PSS2, respectively, in the endoplasmic reticulum and can be reversibly converted back by the same enzymes. It can also be irreversi...
TN3587 Capillarisin

MMP; ERK; IL Receptor; BCL; VEGFR; TNF; NOS; NF-κB; TLR; MAPK; COX; DNA/RNA Synthesis; Prostaglandin Receptor; JNK; STAT Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; JAK/STAT signaling; MAPK; Neuroscience; NF-κB; Proteases/Proteasome; Stem Cells; Tyrosine Kinase/Adaptors
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cells, it inhibits cancer cell growth of osteosarcoma cells by inducing apoptosis accompanied with
T75632 Ganoderic acid T1

Others Others
Ganoderic acid T1是Ganoderic acid T的去乙酰化衍生物,具有促进癌细胞凋亡(apoptosis)的功能。它通过降低线粒体膜电位以及激活caspase-9和caspase-3来引发细胞凋亡,并增加细胞内ROS的产生,从而表现出促氧化活性和细胞性毒作用,同时减弱抗氧化防御系统。
T4700 1,3,5-Trihydroxy-4-prenylxanthone

1,3,5-Trihydroxy-4-prenylxanthone is a relatively potent inhibitor of phosphodiesterase type 5 (PDE5), with an IC50 value of 3.0 μM; it shows in vitro inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with IC50 valu
T35751 Violacein

Others Others
Violacein is a bacterial metabolite originally isolated from C. violaceum that has antibacterial and antiprotozoal activities.[1] [2] It is produced by C. violaceum as a purple pigment in response to N-hexanoyl homoserine lactone , a property that has been modified to create a strain of C. violaceum used in detecting quorum-sensing molecules.[3] Violacein is active against Gram-positive bacteria, including B. subtilis and S. aureus (MICs = 0.8 and 1.6 &#181M, respectively). It is also active aga...
TN3323 Monomethyl lithospermate

Lithospermic acid monomethyl ester

Akt; PI3K Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
Monomethyl lithospermate (Lithospermic acid monomethyl ester) 具有潜在的抗病毒活性,通过激活PI5K/Akt信号传导,减轻体内大脑中动脉闭塞小鼠缺血性中风损伤,并在体外保护氧葡萄糖剥夺/复氧诱导的SHSY-3Y细胞。Monomethyl lithospermate 能提高 SHSY-5Y 细胞的生存能力,抑制线粒体膜电位 (MMOP) 崩溃,抑制细胞凋亡。Monomethyl lithospermate 还降低中动脉闭塞 (MCAO) 大鼠脑组织中的氧化应激水平,改善缺血性中风 (IS) 大鼠神经损伤。
T36954 Nemorosone

Others Others
Nemorosone is a polycyclic polyprenylated acylphloroglucinol (PPAP) originally isolated from C. rosea that has antiproliferative properties.1 Nemorosone inhibits growth of NB69, Kelly, SK-N-AS, and LAN-1 neuroblastoma cells (IC50s = 3.1-6.3 μM), including several drug-resistant clones, but not MRC-5 human embryonic fibroblasts (IC50 = >40 μM).2 It increases DNA fragmentation in LAN-1 cells in a dose-dependent manner, and decreases N-Myc protein levels and phosphorylation of ERK1/2 by MEK1/2. Nem...

天然产物

Sulfentrazone
Cat.No: T21164
Synonym: 甲磺草胺,FP-846
Target: Others
Spermidine trihydrochloride
Cat.No: T5080
Synonym: Spermidine hydrochloride,4-Azaoctamethylenediamine trihydrochloride,三盐酸亚精胺,亚精胺盐酸盐
Target: NMDAR, Autophagy
Spermidine
Cat.No: T4893
Synonym: N-(3-Aminopropyl)-1,4-diaminobutane,亚精胺,N-(4-Aminobutyl)-1,3-diaminopropane
Target: Endogenous Metabolite
Cholesteryl sulfate sodium
Cat.No: T5239
Synonym: Cholesterol 3-Sulfate Sodium Salt,胆固醇硫酸酯钠盐,Sodium Cholesteryl Sulfate
Target: Endogenous Metabolite, PKC
POPE
Cat.No: TF0083
Synonym:
Target:
5α-Cholestan-3-one
Cat.No: T2905
Synonym: 5-Α-胆甾烷-3-酮,Coprostanone,5alpha-Cholestan-3-one
Target: Others, Endogenous Metabolite
1-Nonanol
Cat.No: TN6912
Synonym: Nonan-1-ol
Target: Antifungal
Tioconazole
Cat.No: T0146
Synonym: UK-20349,Vagistat,噻康唑
Target: Antibiotic, Antifection, Antifungal
Lecithin
Cat.No: T3237
Synonym: Phospholutein,卵磷脂,L-α-磷脂酰胆碱,L-α-Phosphatidylcholine,Phosphatidylcholines
Target: Others, Endogenous Metabolite
2,6-Diaminoheptanedioic acid
Cat.No: T4889
Synonym:
Target: Others, Endogenous Metabolite
Terbinafine
Cat.No: T6702
Synonym: Terbinex,特比萘芬,SF 86-327,Lamisil,TDT 067
Target: Antibacterial, Antibiotic, Antifungal
PEP 3CHA
Cat.No: T12451
Synonym: PEP 3 CHA,Phosphoenolpyruvic acid tricyclohexylammonium salt,磷酸烯醇丙酮酸三(环已胺)盐
Target: Others
Hederacolchiside A1
Cat.No: T2P2806
Synonym: 黑海常春藤苷A1,革叶常春藤皂苷 A1,Raddeanoside R13
Target: Apoptosis, ERK, MEK, Akt, PI3K, Parasite, mTOR
DSPS
Cat.No: T21437
Synonym: DSPS (From soybeans),Phosphatidylserine(36:0),磷脂酰丝氨酸,Dioctadecanoylphosphatidylserine,Distearoyl phosphatidylserine
Target: Others
Ethyl cinnamate
Cat.No: TN1624
Synonym:
Target: Calcium Channel, ROS, NO Synthase
Leupeptin Hemisulfate
Cat.No: T6564
Synonym: 亮肽素
Target: Serine Protease, Cysteine Protease
Roemerine
Cat.No: TN2160
Synonym: (-)-Roemerine
Target: Antibiotic
Bacoside A
Cat.No: T3426
Synonym:
Target: MMP, Others, TNF, Dopamine Receptor, NOS, ROS
Cortisone acetate
Cat.No: T0034
Synonym: 醋酸可的松,Cortisone 21-acetate,NSC 49420
Target: Glucocorticoid Receptor, Endogenous Metabolite
Glycerophospholipids, cephalins
Cat.No: T38141
Synonym: Phosphatidylethanolamines (egg)
Target:
Trypsin
Cat.No: TN6872
Synonym:
Target: Protease-activated Receptor
Lipopolysaccharides
Cat.No: T11855
Synonym: 脂多糖,LPS
Target: Others
Calycosin-7-O-β-D-glucoside
Cat.No: T3388
Synonym: 毛蕊异黄酮苷,calycosin-7-O-beta-D-glucopyranoside,Calycosin-7-O-beta-D-glucoside
Target: MMP, Reactive Oxygen Species
Lipopolysaccharides, Escherichiacoli
Cat.No: T41078
Synonym: Lipopolysaccharide, E. coli O111:B4
Target: Others
Hyaluronic acid sodium
Cat.No: T5004
Synonym: 透明质酸钠,Sodium Hyaluronate
Target: Others
Dehydrocorydaline nitrate
Cat.No: T2S2362
Synonym: 去氢延胡索甲素硝酸盐,硝酸脱氢紫堇碱
Target: BCL, Others, PARP, p38 MAPK, Caspase, Parasite, Autophagy
Triamcinolone
Cat.No: T0798
Synonym: Fluoxyprednisolone,曲安西龙,Aristocort,Rodinolone
Target: Glucocorticoid Receptor, COX
Tricosanoic acid
Cat.No: T4855
Synonym: Tricosan-1-oic acid,二十三烷酸
Target: Endogenous Metabolite
Phosphorylethanolamine
Cat.No: T4881
Synonym: O-Phosphorylethanolamine,乙醇胺磷酸酯
Target: Others, Endogenous Metabolite
Fengycin
Cat.No: T37876
Synonym:
Target: Others
Licopyranocoumarin
Cat.No: TN4435
Synonym:
Target: P450, ROS, JNK
Iturin A
Cat.No: T40600
Synonym:
Target: Others
K-252b
Cat.No: T15637
Synonym:
Target: PKC
Zymosterol
Cat.No: T73808
Synonym:
Target: Others
Aspochracin
Cat.No: TN7555
Synonym: Aspochracin
Target: Others
2'-epi-2'-O-Acetylthevetin B
Cat.No: T79982
Synonym: GHSC-74
Target: Apoptosis
Kuwanon B
Cat.No: TN2445
Synonym:
Target: Others
Phosphatidylserines (bovine)
Cat.No: T35577
Synonym:
Target: Others
Capillarisin
Cat.No: TN3587
Synonym:
Target: MMP, ERK, IL Receptor, BCL, VEGFR, TNF, NOS, NF-κB, TLR, MAPK, COX, DNA/RNA Synthesis, Prostaglandin Receptor, JNK, STAT
Ganoderic acid T1
Cat.No: T75632
Synonym:
Target: Others
1,3,5-Trihydroxy-4-prenylxanthone
Cat.No: T4700
Synonym:
Target:
Violacein
Cat.No: T35751
Synonym:
Target: Others
Monomethyl lithospermate
Cat.No: TN3323
Synonym: Lithospermic acid monomethyl ester
Target: Akt, PI3K
Nemorosone
Cat.No: T36954
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPY-04139 MCEMP1 Protein, Human, Recombinant (mFc)

C19orf59,mast cell-expressed membrane prot...

Human HEK293 Cells
MCEMP1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 36 kDa and the accession number is A0A384NYE9.
TMPJ-00624 TIM-3/KIM-3/HAVCR2 Protein, Marmoset, Recombinant (His)

Tim3,HAVcr-2,Timd3,Hepatitis A virus cellular recep...

Marmoset HEK293 Cells
TIM-3/KIM-3/HAVCR2 Protein, Marmoset, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 30-45 KDa and the accession number is F7I881.
TMPH-03146 LAMP5 Protein, Pongo abelii, Recombinant (His & Myc)

Lysosome-associated membrane glycoprotein 5,LAMP5,B...

Pongo abelii E. coli
Plays a role in short-term synaptic plasticity in a subset of GABAergic neurons in the brain. LAMP5 Protein, Pongo abelii, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 30.4 kDa and the accession number is Q5R5V2.
TMPJ-00173 TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-191, His)

T-cell membrane protein 3,T-cell ...

Mouse HEK293 Cells
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-191, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 30-50 KDa and the accession number is Q8VIM0.
TMPH-03350 Pmp22 Protein, Rat, Recombinant (His)

Peripheral myelin protein 22,Schwann cell membr...

Rat E. coli
Might be involved in growth regulation, and in myelinization in the peripheral nervous system. Pmp22 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 23.4 kDa and the accession number is P25094.
TMPJ-00174 TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-193, His)

T-cell immunoglobulin mucin receptor 3,Hepatitis A ...

Mouse HEK293 Cells
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-193, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-55 KDa and the accession number is Q8VIM0.
TMPH-01299 EMC4 Protein, Human, Recombinant (His)

TMEM85,EMC4,ER membrane protein complex subunit 4,T...

Human E. coli
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues. Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spann...
TMPH-02192 Tetraspanin-7/TSPAN7 Protein, Human, Recombinant (E. coli, His)

Transmembrane 4 superfamily member 2,TSPAN7,Mem...

Human E. coli
May be involved in cell proliferation and cell motility. Tetraspanin-7/TSPAN7 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 15.6 kDa and the accession number is P41732.
TMPJ-00599 TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc & His)

TIM3,Hepatitis A virus cellular receptor 2,KIM-3,T-...

Human HEK293 Cells
Hepatitis A virus cellular receptor 2(HAVCR2)is a single-pass type I membrane protein and it contains 1 Ig-like V-type (immunoglobulin-like) domain. The protein belongs to the immunoglobulin superfamily, and TIM family of proteins. The protein regulates macrophage activation. It inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. It may be also involved in T-cell homing and it is receptor for LGALS9. CD4 (MIM 186940)-positive T ...
TMPJ-00206 TROP-2 Protein, Human, Recombinant (aa 27-274, hFc)

Membrane component chromosome 1 surface marker 1,TA...

Human HEK293 Cells
Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions. TROP-2 Protein, Human, Re...
TMPH-02193 Tetraspanin-7/TSPAN7 Protein, Human, Recombinant (His)

Cell surface glycoprotein A15,Membrane com...

Human P. pastoris (Yeast)
May be involved in cell proliferation and cell motility. Tetraspanin-7/TSPAN7 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 14.5 kDa and the accession number is P41732.
TMPJ-00205 TROP-2 Protein,Human,Recombinant (aa 88-274, hFc)

Tumor-associated calcium signal transducer 2,TROP2,Cell<...

Human HEK293 Cells
Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions. TROP-2 Protein,Human,Reco...
TMPJ-00204 TROP-2 Protein, Human, Recombinant (Avi & His), Biotinylated

TACSTD2,Cell surface glycoprotein Trop-2,Membra...

Human HEK293 Cells
Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions. TROP-2 Protein, Human, Re...
TMPJ-00423 TIM-1/KIM-1/HAVCR1 Protein, Mouse, Recombinant (His)

Hepatitis A virus cellular receptor 1 homolog,HAVcr...

Mouse HEK293 Cells
TIM-1/KIM-1/HAVCR belongs to the immunoglobulin superfamily that cosisits 305 amino acid (aa). It is expressed by stimulated T-cells. TIM-1/KIM-1/HAVCR may play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. And may have a role in kidney injury and repair. Belongs to the T-cell and airway phenotype regulator (Tapr) locus, a single chromosomal region that confers reduced T-helper type 2 responsiveness and protects against airway hypera...
TMPJ-00382 P-selectin Protein, Mouse, Recombinant (Avi & His), Biotinylated

PADGEM,CD62 antigen-like family member P,Granule membran...

Mouse HEK293 Cells
P-selectin/CD62P is a single-pass type I membrane protein which is a member of the Selectin family. It consists 768 amino acid (aa). P-selectin is a cell surface glycoprotein expressed by activated platelets and endothelial cells. It induced expression in lung, liver, kidney and heart after endotoxin treatment. Ca2+-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. It mediates the interaction of activated endothelial cells or platelets with leukocytes...
TMPJ-00097 NKG2D/CD314 Protein, Cynomolgus, Recombinant (hFc)

member 1,NK cell receptor D,NKG2-D-activating NK re...

Cynomolgus HEK293 Cells
NKG2D/CD314 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-Fc tag. The predicted molecular weight is 50-70 KDa and the accession number is P61252.
TMPJ-00122 NKG2D/CD314 Protein, Mouse, Recombinant (His)

KLR,NKG2-D type II integral membrane protein,CD314,...

Mouse HEK293 Cells
NKG2D/CD314 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 20-30 KDa and the accession number is O54709.
TMPH-01036 Caprin-1/CAPRIN1 Protein, Human, Recombinant (His)

GPI-anchored membrane protein 1,CAPRIN1,GPIP137,M11...

Human Baculovirus Insect Cells
May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs. Caprin-1/CAPRIN1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells ...
TMPJ-01323 NTAL Protein, Human, Recombinant (His)

Williams-Beuren Syndrome Chromosomal Region 5 P,Membrane...

Human HEK293 Cells
Linker for Activation of T-Cells Family Member 2 (LAT2) is a single-pass type III membrane protein. LAT2 is highly expressed in the spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. LAT2 is involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. It may also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. ...
TMPJ-01218 M-CSF/CSF1 Protein, Rat, Recombinant

CSF1,集落刺激因子,CSF-1,Macrophage colony-stimulating factor 1,M-C...

Rat HEK293 Cells
Rat Macrophage colony-stimulating factor 1(MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regu...
TMPY-03650 BirA Protein, E. coli, Recombinant (His & MBP)

BirA,dhbB,bioR

E. coli E. coli
The enzyme BirA is a key reagent because of its ability to biotinylate proteins at a specific residue in a recognition sequence. This enzyme is used to biotinylate the C termini of membrane proteins, allowing these proteins to be tetramerized by binding to streptavidin. Because of the specificity of the biotinylation at the C terminus, the orientation of the membrane proteins on the streptavidin is equivalent to that of the native protein on the cell surface. These tetrameric proteins can be use...
TMPY-00570 Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His)

ALPI,PALP,PLAP,PLAP-1,alkaline phosphatase, placental,IAP,AL...

Human P. pastoris (Yeast)
Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyrosine phosphates on the surface of the magnetic nanoparticle and enable the magnetic nanoparticles to adhere selectively to the cancer cells, such as HeLa cells. Placental alkaline phosphatase (PLAP), encoded by the ALPP gene, is produced by the fetal side of the placenta.
TMPY-04853 TSHR Protein, Human, Recombinant (His)

TSHR,hTSHR-I,TSH Receptor,LGR3,CHNG1

Human Baculovirus Insect Cells
Thyroid-stimulating hormone (TSH) is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated with hypothyroidism. Immunohistochemical analysis revealed predominantly nuclei/peri-nuclei localization of TSHR in cancerous tissues but cell membrane localization in non-cancerous parts. Overexpression of TSHR was found in a great majority of HCC tissues and associated with unfavorable prognosis.
TMPY-02204 LBP Protein, Human, Recombinant (His)

BPIFD2,lipopolysaccharide binding protein

Human HEK293 Cells
Lipopolysaccharide binding protein ( LBP ) is a glycoprotein that is synthesized principally by hepatocytes. LBP is a trace plasma protein that binds to the lipid A moiety of bacterial lipopolysaccharides ( LPSs ). LBP binds directly to the outer membrane of Gram-negative bacteria and purified aggregates of extracted endotoxin and catalyzes the delivery of endotoxin to the membrane ( mCD14, GPI-Linked ) and soluble ( sCD14 ) forms of CD14, thereby markedly increasing host cell sensitivity to end...
TMPJ-00327 M-CSF/CSF1 Protein, Human, Recombinant (His)

Lanimostim,M-CSF,CSF-1,MCSF,CSF1,集落刺激因子,Macrophage Colony-St...

Human HEK293 Cells
Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulatio...
TMPY-02292 IGSF11 Protein, Human, Recombinant (His)

CT119,immunoglobulin superfamily, member 11,BT-IgSF,Igsf13,C...

Human HEK293 Cells
Immunoglobulin superfamily member 11(IGSF11) is expressed on the plasma membrane in the testis and brain. These IGSF proteins undergo final modifications during capacitation and/or the acrosome reaction. IGSF proteins share significant homology with endothelial cell-selective adhesion molecule and coxsackievirus and adenovirus receptor, which mediates cell attachment and homotypic intercellular interactions. In clinical, the IGSF11 has been reported to overexpressed in colorectal cancers and hep...
TMPY-02245 SNAP-25 Protein, Human, Recombinant (His)

synaptosomal-associated protein, 25kDa,SEC9,SNAP,RIC-4,dJ106...

Human E. coli
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the sp...
TMPY-00369 LY6D Protein, Human, Recombinant (mFc)

E48,lymphocyte antigen 6 complex, locus D,Ly-6D

Human HEK293 Cells
LY6D (Lymphocyte Antigen 6 Family Member D) is a Protein Coding gene. It may act as a specification marker at the earliest stage specification of lymphocytes between B- and T-cell development. Marks the earliest stage of B-cell specification. The expression of LY6D is induced in MCF10A cells by X-ray irradiation. The induction of LY6D expression is triggered through a pathway regulated by ATM, CHK2, and p53. This method is a new Ab-directed proteomic strategy for the analysis of membrane protein...
TMPY-00817 Granzyme B/GZMB Protein, Human, Recombinant (His)

CGL1,CTLA1,CSP-B,CTSGL1,HLP,SECT,CSPB,granzyme B (granzyme 2...

Human HEK293 Cells
Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the target cells depending on another membrane-binding granule protein, perforin, results in the activation of effector caspases and mitochondrial depolarization through caspase-dependent and -independent pathways, and consequently induces rapid cell apoptosis. Over 3 substrates of G...
TMPY-02525 RGMA Protein, Human, Recombinant (His)

repulsive guidance molecule family member a,RGM

Human HEK293 Cells
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that form...
TMPY-01806 CD9 Protein, Human, Recombinant (His)

BTCC-1,DRAP-27,TSPAN29,MRP-1,CD9 molecule,MIC3,TSPAN-29

Human HEK293 Cells
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d...
TMPY-01648 TREML2 Protein, Human, Recombinant (His)

TLT2,dJ238O23.1,triggering receptor expressed on myeloid

Human HEK293 Cells
Trem-like transcript 2 protein, also known as Triggering receptor expressed on myeloid cells-like protein 2, TREML2 and TLT2, is a single-pass type I membrane protein that contains one Ig-like V-type (immunoglobulin-like) domain. TREML2 is detected in cultured B cells, T cell leukemia and monocyte leukemia. TREML2 is expressed constitutively on CD8 T-cells and induced on CD4 T-cells after activation. TREML2 is a cell surface receptor that may play a role in the innate and adaptive immune respons...
TMPY-03758 Vaccinia Virus B18R/B19R Protein (His)

VACV Baculovirus Insect Cells
B18R is a type I interferon (IFN)-binding protein, which is encoded by the B18R open reading frame in the WR (Western Reserve) strain of vaccinia virus. It is also known as B19R in the Copenhagen strain of Vaccinia. B18R exists in a soluble and a membrane-bound form. As a type I IFN receptor, B18R has a broad species specificity. It has high affinity for human IFN-alpha and also binds rabbit, bovine, rat, pig, and mouse IFN-alpha and IFN-beta. It has been shown that secreted B18R binds to un...
TMPY-02700 BCL2 Protein, Human, Recombinant (His)

Bcl-2,PPP1R50,B-cell CLL/lymphoma 2

Human E. coli
BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family and all members contain at least one of four BH (bcl-2 homology) domains. Certain members such as Bcl-2, Bcl-xl and Mcl1 are anti-apoptotic, whilst others are pro-apoptotic. Most Bcl-2 family members contain a C-terminal transmembrane domain that functions to target these proteins...
TMPY-02030 CD82 Protein, Human, Recombinant (His)

CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,TSPAN27,ST6,IA4,GR1...

Human HEK293 Cells
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud...
TMPY-04396 C-ABL/ABL1 Protein, Human, Recombinant (GST)

v-abl,ABL,JTK7,ABL proto-oncogene 1, non-receptor tyrosine k...

Human Baculovirus Insect Cells
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity an...
TMPY-01964 CD16a Protein, Human, Recombinant (F176V, His)

FCGRIII,Fc gamma RIIIa,FCR-10,FCRIII,FCRIIIA,FCGR3,CD16A,Fc...

Human HEK293 Cells
The Fc receptor with low affinity for IgG (FCGR3, or CD16) is encoded by 2 nearly identical genes, FCGR3A and FCGR3B, resulting in tissue-specific expression of alternative membrane-anchored isoforms. FCGR3A, it is also known as CD16a, encodes a transmembrane protein expressed on activated monocytes/macrophages, natural killer (NK) cells, and a subset of T cells. CD16a / FCGR3A is a receptor expressed on NK cells that facilitates antibody dependent cellular cytotoxicity (ADCC) by binding to the...
TMPY-02078 HtrA2/Omi Protein, Human, Recombinant (His)

PARK13,OMI,HtrA serine peptidase 2,PRSS25

Human E. coli
Serine protease HTRA2, also known as high-temperature requirement protein A2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI and HTRA2, is a single-pass membrane protein that belongs to the peptidase S1B family. HTRA2 contains one PDZ (DHR) domain. HTRA2 is a serine protease that shows proteolytic activity against a non-specific substrate beta-casein. It promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor...
TMPJ-00994 LTBR Protein, Mouse, Recombinant (hFc)

Tnfcr,Lymphotoxin-beta receptor,Tumor necrosis factor recept...

Mouse HEK293 Cells
It is a single-pass type I membrane protein and contains 4 TNFR-Cys repeats. The protein is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein is the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. It promotes apoptosis via TRAF3 and TRAF5 and may play a role in the development of lymphoid organs...
TMPH-02271 BTK Protein, Human, Recombinant (His)

BPK,AGMX1,ATK,B-cell progenitor kinase,Tyrosine-pro...

Human Baculovirus Insect Cells
Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in...
TMPH-02399 Pal Protein, Legionella pneumophila, Recombinant (E. coli, His)

pal,19 kDa surface antigen,Peptidoglycan-associated lipoprot...

Legionella pneumophila E. coli
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Very strongly associated with the peptidoglycan.
TMPH-00716 RzoR Protein, E. coli, Recombinant (Flag & His)

Prophage outer membrane lipoprotein RzoR,Spanin fro...

E. coli E. coli
Component of the spanin complex that disrupts the outer membrane and causes cell lysis during virus exit. The spanin complex conducts the final step in cell lysis by disrupting the outer membrane after holin and endolysin action have permeabilized the inner membrane and degraded the host peptidoglycans.
TMPH-03659 Vaccinia virus (strain Western Reserve) OPG094 Protein (His)

Protein F1,Myristoylated protein G9,Entry-fusion complex pro...

VACV P. pastoris (Yeast)
Envelope protein part of the entry-fusion complex responsible for the virus membrane fusion with host cell membrane during virus entry. Also plays a role in cell-cell fusion (syncytium formation). Vaccinia virus (strain Western Reserve) OPG094 Protein (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 37.8 kDa and the accession number is P07611.
TMPH-00703 Pal Protein, E. coli, Recombinant (His & Myc)

Peptidoglycan-associated lipoprotein,pal,Tol-Pal system lipo...

E. coli E. coli
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. The Tol-Pal system is also required for polar localization of chemoreceptors clusters. The system also appears to be required for the activity of several outer membrane-localized enzymes with cell wall remodeling activity.
TMPH-03036 Cytotoxin 2 Protein, Naja atra, Recombinant (His & Myc)

Cardiotoxin 2,CTX A2,Cardiotoxin 1A,Cardiotoxin A2,Cardiotox...

Naja atra E. coli
Basic protein that binds to cell membrane and depolarizes cardiomyocytes. It also shows lytic activities, but 2-fold less important than that of CTX-A4. It binds to the integrin alpha-V/beta-3 (ITGAV/ITGB3) with a moderate affinity. It may interact with sulfatides in the cell membrane which induces pore formation and cell internalization and is responsible for cytotoxicity in cardiomyocytes. It also may target the mitochondrial membrane and induce mitochondrial swelling and fragmentation.
TMPH-03086 Pal Protein, Pasteurella multocida, Recombinant (His & SUMO)

Peptidoglycan-associated lipoprotein,pal,Outer membrane<...

Pasteurella multocida E. coli
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Pal Protein, Pasteurella multocida, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 27.3 kDa and the accession number is Q51886.
TMPH-02400 Pal Protein, Legionella pneumophila, Recombinant (His)

19 kDa surface antigen,Peptidoglycan-associated lipoprotein,...

Legionella pneumophila P. pastoris (Yeast)
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Very strongly associated with the peptidoglycan.
TMPH-00552 Lpp Protein, Erwinia amylovora, Recombinant (His & SUMO)

Major outer membrane lipoprotein Lpp,lpp

Erwinia amylovora E. coli
A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
TMPH-01291 ERVK-7 Protein, Human, Recombinant (His)

Endogenous retrovirus group K member 7 Env polyprotein,HERV-...

Human E. coli
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution.; SU mediates receptor recognition.; TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane.
TMPH-00651 Lpp Protein, E. coli, Recombinant (His & KSI)

Major outer membrane lipoprotein Lpp,Braun lipoprot...

E. coli E. coli
An outer membrane lipoprotein that controls the distance between the inner and outer membranes; adding residues to Lpp increases the width of the periplasm. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to the maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane. The m...
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重组蛋白

MCEMP1 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-04139
Species: Human
Expression System: HEK293 Cells
TIM-3/KIM-3/HAVCR2 Protein, Marmoset, Recombinant (His)
Cat.No: TMPJ-00624
Species: Marmoset
Expression System: HEK293 Cells
LAMP5 Protein, Pongo abelii, Recombinant (His & Myc)
Cat.No: TMPH-03146
Species: Pongo abelii
Expression System: E. coli
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-191, His)
Cat.No: TMPJ-00173
Species: Mouse
Expression System: HEK293 Cells
Pmp22 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03350
Species: Rat
Expression System: E. coli
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-193, His)
Cat.No: TMPJ-00174
Species: Mouse
Expression System: HEK293 Cells
EMC4 Protein, Human, Recombinant (His)
Cat.No: TMPH-01299
Species: Human
Expression System: E. coli
Tetraspanin-7/TSPAN7 Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-02192
Species: Human
Expression System: E. coli
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-00599
Species: Human
Expression System: HEK293 Cells
TROP-2 Protein, Human, Recombinant (aa 27-274, hFc)
Cat.No: TMPJ-00206
Species: Human
Expression System: HEK293 Cells
Tetraspanin-7/TSPAN7 Protein, Human, Recombinant (His)
Cat.No: TMPH-02193
Species: Human
Expression System: P. pastoris (Yeast)
TROP-2 Protein,Human,Recombinant (aa 88-274, hFc)
Cat.No: TMPJ-00205
Species: Human
Expression System: HEK293 Cells
TROP-2 Protein, Human, Recombinant (Avi & His), Biotinylated
Cat.No: TMPJ-00204
Species: Human
Expression System: HEK293 Cells
TIM-1/KIM-1/HAVCR1 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00423
Species: Mouse
Expression System: HEK293 Cells
P-selectin Protein, Mouse, Recombinant (Avi & His), Biotinylated
Cat.No: TMPJ-00382
Species: Mouse
Expression System: HEK293 Cells
NKG2D/CD314 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPJ-00097
Species: Cynomolgus
Expression System: HEK293 Cells
NKG2D/CD314 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00122
Species: Mouse
Expression System: HEK293 Cells
Caprin-1/CAPRIN1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01036
Species: Human
Expression System: Baculovirus Insect Cells
NTAL Protein, Human, Recombinant (His)
Cat.No: TMPJ-01323
Species: Human
Expression System: HEK293 Cells
M-CSF/CSF1 Protein, Rat, Recombinant
Cat.No: TMPJ-01218
Species: Rat
Expression System: HEK293 Cells
BirA Protein, E. coli, Recombinant (His & MBP)
Cat.No: TMPY-03650
Species: E. coli
Expression System: E. coli
Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His)
Cat.No: TMPY-00570
Species: Human
Expression System: P. pastoris (Yeast)
TSHR Protein, Human, Recombinant (His)
Cat.No: TMPY-04853
Species: Human
Expression System: Baculovirus Insect Cells
LBP Protein, Human, Recombinant (His)
Cat.No: TMPY-02204
Species: Human
Expression System: HEK293 Cells
M-CSF/CSF1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00327
Species: Human
Expression System: HEK293 Cells
IGSF11 Protein, Human, Recombinant (His)
Cat.No: TMPY-02292
Species: Human
Expression System: HEK293 Cells
SNAP-25 Protein, Human, Recombinant (His)
Cat.No: TMPY-02245
Species: Human
Expression System: E. coli
LY6D Protein, Human, Recombinant (mFc)
Cat.No: TMPY-00369
Species: Human
Expression System: HEK293 Cells
Granzyme B/GZMB Protein, Human, Recombinant (His)
Cat.No: TMPY-00817
Species: Human
Expression System: HEK293 Cells
RGMA Protein, Human, Recombinant (His)
Cat.No: TMPY-02525
Species: Human
Expression System: HEK293 Cells
CD9 Protein, Human, Recombinant (His)
Cat.No: TMPY-01806
Species: Human
Expression System: HEK293 Cells
TREML2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01648
Species: Human
Expression System: HEK293 Cells
Vaccinia Virus B18R/B19R Protein (His)
Cat.No: TMPY-03758
Species: VACV
Expression System: Baculovirus Insect Cells
BCL2 Protein, Human, Recombinant (His)
Cat.No: TMPY-02700
Species: Human
Expression System: E. coli
CD82 Protein, Human, Recombinant (His)
Cat.No: TMPY-02030
Species: Human
Expression System: HEK293 Cells
C-ABL/ABL1 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04396
Species: Human
Expression System: Baculovirus Insect Cells
CD16a Protein, Human, Recombinant (F176V, His)
Cat.No: TMPY-01964
Species: Human
Expression System: HEK293 Cells
HtrA2/Omi Protein, Human, Recombinant (His)
Cat.No: TMPY-02078
Species: Human
Expression System: E. coli
LTBR Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00994
Species: Mouse
Expression System: HEK293 Cells
BTK Protein, Human, Recombinant (His)
Cat.No: TMPH-02271
Species: Human
Expression System: Baculovirus Insect Cells
Pal Protein, Legionella pneumophila, Recombinant (E. coli, His)
Cat.No: TMPH-02399
Species: Legionella pneumophila
Expression System: E. coli
RzoR Protein, E. coli, Recombinant (Flag & His)
Cat.No: TMPH-00716
Species: E. coli
Expression System: E. coli
Vaccinia virus (strain Western Reserve) OPG094 Protein (His)
Cat.No: TMPH-03659
Species: VACV
Expression System: P. pastoris (Yeast)
Pal Protein, E. coli, Recombinant (His & Myc)
Cat.No: TMPH-00703
Species: E. coli
Expression System: E. coli
Cytotoxin 2 Protein, Naja atra, Recombinant (His & Myc)
Cat.No: TMPH-03036
Species: Naja atra
Expression System: E. coli
Pal Protein, Pasteurella multocida, Recombinant (His & SUMO)
Cat.No: TMPH-03086
Species: Pasteurella multocida
Expression System: E. coli
Pal Protein, Legionella pneumophila, Recombinant (His)
Cat.No: TMPH-02400
Species: Legionella pneumophila
Expression System: P. pastoris (Yeast)
Lpp Protein, Erwinia amylovora, Recombinant (His & SUMO)
Cat.No: TMPH-00552
Species: Erwinia amylovora
Expression System: E. coli
ERVK-7 Protein, Human, Recombinant (His)
Cat.No: TMPH-01291
Species: Human
Expression System: E. coli
Lpp Protein, E. coli, Recombinant (His & KSI)
Cat.No: TMPH-00651
Species: E. coli
Expression System: E. coli
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Cat. No. Product Name Target Signaling Pathways
TMIJ-0157 Cefoperazone-d5

Cefoperazone-d5 是 Cefoperazone 的氘代化合物。Cefoperazone 的 CAS 号为 62893-19-0。Cefoperazone是一种半合成的头孢菌素,有抗菌活性。
T70808 Cabazitaxel-d6

Cabazitaxel-d6 is a deuterium labeled cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. Cabazitaxel binds to and stabilizes tubulin, resulting in the inhibition of microtubule depolymerization and cell division, cell cycle arrest in the G2/M phase, and the inhibition of tumor cell proliferation. Unlike other taxane compounds, this agent is a poor substrate for the membrane-associated, multidrug resistance...
TMID-0083 Arbidol-d6 Hydrochloride

Arbidol-d6 Hydrochloride 是 Arbidol Hydrochloride 的氘代化合物。Arbidol Hydrochloride 的 CAS 号为 131707-23-8。Umifenovir hydrochloride 是一种口服有效的广谱抗病毒药物,对多种包膜和非包膜病毒均有活性。它被用作抗流感病毒剂,可通过阻断病毒与宿主细胞膜的融合来抑制包膜病毒的细胞侵袭。它是一种 SARS-CoV-2 抑制剂,具有抗炎活性。
T71981 Gliclazide-d4

Gliclazide-d4 is intended for use as an internal standard for the quantification of gliclazide by GC- or LC-MS. Gliclazide is a sulfonylurea and an inhibitor of pancreatic β-cell ATP-sensitive potassium (KATP) channels. It is selective for pancreatic β-cell over cardiac and arterial smooth muscle cell KATP channels. Gliclazide (5 μM) increases insulin-induced glucose uptake and glucose transporter 4 (GLUT4) translocation to the plasma membrane in a differentiated 3T3L1 adipocyte model of insulin...
T35695 Oleic Acid-13C

Oleic acid-13C is intended for use as an internal standard for the quantification of oleic acid by GC- or LC-MS. Oleic acid is a monounsaturated fatty acid and a major component of membrane phospholipids that has been found in human plasma, cell membranes, and adipose tissue.1,2 It contributes approximately 17% of the total fatty acids esterified to phosphatidylcholine, the major phospholipid class in porcine platelets.1 Oleic acid inhibits collagen-stimulated platelet aggregation by approximate...
T35790 Palmitic acid-1,2,3,4-13C4

Palmitic Acid-13C (C1, C2, C3, and C4 labeled)

Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellula...
T35789 Palmitic acid-1-13C

Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.1 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.2 Palmitic acid is involved in the acylation of proteins to anchor membrane-bound proteins to the lipid bilayer.2,3,4,5,6 |1. Santos, M.J., López-Jurado, M., Llopis, J., et a...
T35791 Palmitic acid-13C

Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid-13C contains 13C at the C2 position and has been used in the study of free fatty acid incorporation into phospholipid fatty acids in soil microbes.1 Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.2 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.3 Palmitic ...

同位素标记化合物

Cefoperazone-d5
Cat.No: TMIJ-0157
Synonym:
Target:
Cabazitaxel-d6
Cat.No: T70808
Synonym:
Target:
Arbidol-d6 Hydrochloride
Cat.No: TMID-0083
Synonym:
Target:
Gliclazide-d4
Cat.No: T71981
Synonym:
Target:
Oleic Acid-13C
Cat.No: T35695
Synonym:
Target:
Palmitic acid-1,2,3,4-13C4
Cat.No: T35790
Synonym: Palmitic Acid-13C (C1, C2, C3, and C4 labeled)
Target:
Palmitic acid-1-13C
Cat.No: T35789
Synonym:
Target:
Palmitic acid-13C
Cat.No: T35791
Synonym:
Target:
TargetMol Loading
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