1166
197
2
55
34
Cat. No. | Product Name | ||
---|---|---|---|
L2550 | 谷氨酰胺代谢化合物库 | 565 compounds | |
565 种谷氨酰胺代谢相关的分子,可以用于高通量和高内涵筛选; | |||
L3300 | 组胺&褪黑色素化合物库 | 153 compounds | |
153 种生物活性小分子化合物,用于高通量、高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T20967 |
Methyltetrazine-Amine
Methyltetrazine amine |
PROTACs | PROTAC |
Methyltetrazine-Amine 是甲基取代的四嗪胺,可用于合成 PROTAC 分子。 | |||
T23535L |
Xanthine amine congener trihydrochloride
Xanthine amine congener trihydrochloride (96865-92-8 Free base) |
Adenosine Receptor | GPCR/G Protein; Neuroscience |
Xanthine amine congener trihydrochloride 是一种有效的腺苷拮抗剂,可逆转由腺苷激动剂 N6-环己基腺苷产生的尿流量、钠排泄和心率的减少。 | |||
T36020 |
Florfenicol amine hydrochloride
|
Antibiotic | Microbiology/Virology |
Florfenicol amine hydrochloride 是一种人工合成的兽用抗生素,具有抗菌活性。Florfenicol amine hydrochloride 在水产养殖业和牧业养殖业中应用广泛,可以用来研究巴氏杆菌、爱德华氏菌、大肠杆菌和沙门氏杆菌引起的疾病。 | |||
T15058 |
DBCO-amine
|
ADC Linker | Antibody-drug Conjugate/ADC Related |
DBCO-amine 是一种可切割的 ADC 接头,用于合成抗体-药物偶联物。 | |||
TP1545L1 |
FFAGLDD amine salt
|
Others | Others |
FFAGLDD amine salt 是MMP9选择性裂解肽,用于多柔比星(DOX)的胞浆递送,实现时间和空间可控的缓慢药物递送和释放。 | |||
T17595 |
Biotin-PEG8-amine
|
PROTACs | PROTAC |
Biotin-PEG8-amine 是一种属于 PEG 类的 PROTAC linker,可用于合成 PROTAC 分子。 | |||
T14220 |
Amine-PEG3-Biotin
|
Others | Others |
Amine-PEG3-Biotin 可用作信号放大标记。 | |||
T15839 |
m-PEG12-amine
|
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
m-PEG12-amine是一种基于PEG的PROTAC连接器,同时也是一种在PROTACs[1]和抗体药物偶联物(ADCs)[2]的合成中使用的不可切割的12单位PEG ADC连接器。 | |||
T14250 |
Amino-PEG8-amine
|
Others | Others |
Amino-PEG8-amine 是一种以聚乙二醇为基础的 PROTAC 连接剂,可用于PROTACs 的合成,是一种含有两个氨基(NH2)基团的共轭PEG 衍生物。 | |||
T17411 |
Amino-PEG13-amine
H2N-PEG13-CH2CH2NH2 |
Others; PROTAC Linker | Others; PROTAC |
Amino-PEG13-amine (H2N-PEG13-CH2CH2NH2) 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T7683 |
Adenosine amine congener
ADAC |
Adenosine Receptor | GPCR/G Protein; Neuroscience |
Adenosine amine congener (ADAC) 是一种选择性的 A1 腺苷受体激动剂,具有神经保护作用,可以改善噪音和顺铂引起的耳蜗损伤。 | |||
T35478 |
cis VH 032, amine dihydrochloride
(S,S,S)-AHPC |
||
cis VH 032, amine dihydrochloride ((S,S,S)-AHPC) 是 功能性 VHL ligand VH 032, amine 的阴性对照. | |||
T14226 |
Amino-PEG11-amine
氨基-十二聚乙二醇-氨基 |
Others; PROTAC Linker | Others; PROTAC |
Amino-PEG11-amine 是一种基于 PEG(12 个单位)的 PROTAC 接头,能够结合两种基于单乙基雌酚的配体,是制备用于乳腺癌内分泌治疗的更具选择性和活性的 ER 拮抗剂的替代策略。 | |||
T17397 |
Amine-PEG-CH2COOH (MW 2000)
|
Others; PROTAC Linker | Others; PROTAC |
Amine-PEG-CH2COOH (MW 2000) 是一种基于 PEG 的 PROTAC 接头,可用于合成 PROTAC。 | |||
T50052 |
1,2-diphenylpropan-2-amine
|
Others | Others |
1,2-diphenylpropan-2-amine 是Remacemide 的(S,R)-异构体单盐酸盐代谢产物。1,2-diphenylpropan-2-amine 具有抗惊厥作用。 | |||
T0565 |
Bis(2-chloroethyl)amine hydrochloride
|
Others | Others |
Bis(2-chloroethyl)amine hydrochloride 用作医药中间体。 | |||
T17407 |
Amino-PEG12-amine
H2N-PEG12-CH2CH2NH2,PEODA13,氨基十三聚乙二醇氨基 |
Others; PROTAC Linker | Others; PROTAC |
Amino-PEG12-amine (H2N-PEG12-CH2CH2NH2) 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T7086 |
Tris(benzyltriazolylmethyl)amine
三[(1-苄基-1H-1,2,3-三唑-4-基)甲基]胺,TBTA |
Others | Others |
Tris(benzyltriazolylmethyl)amine (TBTA) 是一种能作为生化工具的配体,可用于标记蛋白质和酶。 | |||
T19507 |
Perfluamine
FTPA,Tris(perfluoropropyl)amine,Perfluorotripropylamine |
Others | Others |
Perfluamine (FTPA) 是一种疏水性载液,可用作血液替代品。 | |||
T3295 |
1-Methyl-1H-pyrazol-3-amine
|
Others | Others |
1-Methyl-1H-pyrazol-3-amine 是一种吡唑类化合物。它已被用于合成各种化合物,如药物、染料和聚合物。它也是合成某些药物的重要中间体。它还被用于新药的开发,以及酶抑制剂和受体调节剂的研究。 | |||
T50096 |
Neramexane HCl
1,3,3,5,5-pentamethylcyclohexan-1-amine HCl |
Others | Others |
1,3,3,5,5-pentamethylcyclohexan-1-amine hydrochloride,又称PAC,是一种环胺,通常用作不对称合成中的手性助剂,包括Diels-Alder 反应、羟醛反应和Michael 加成。 | |||
T40818 |
Folate-PEG3-amine
Folate-PEG3-amine |
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
Folate-PEG3-amine is a three-unit polyethylene glycol (PEG) linker, which is cleavable. This linker is specifically employed in the synthesis of antibody-drug conjugates (ADCs). | |||
T39832 |
Amine-PEG4-Desthiobiotin
Amine-PEG4-Desthiobiotin |
Others | Others |
Amine-PEG4-Desthiobiotin is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T40983 |
Benzyl-PEG4-amine
Benzyl-PEG4-amine |
Others | Others |
Benzyl-PEG4-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T40030 |
Thalidomide 4'-ether-alkylC2-amine hydrochloride
halidomide-linker 6 |
E3 Ligase Ligand-Linker Conjugate | PROTAC |
Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) 包含基于 Thalidomide 的 cereblon 配体和 linker,是合成的 E3 连接酶配体-linker 偶联物,可应用于 PROTAC 技术。 | |||
T38492 |
Folate-PEG2-amine
Folate-PEG2-amine |
Others | Others |
Folate-PEG2-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T40986 |
Benzyl-PEG7-amine
Benzyl-PEG7-amine |
Others | Others |
Benzyl-PEG7-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T18391 |
N-Boc-4-pentyne-1-amine
|
Others; PROTAC Linker | Others; PROTAC |
N-Boc-4-pentyne-1-amine 是一种基于烷基链的PROTAC连结剂,用于PROTAC MG-277[1]的合成。 | |||
T50042 |
5-phenylthieno[2,3-d]pyrimidin-4-amine
|
ALK | Angiogenesis; Tyrosine Kinase/Adaptors |
5-phenylthieno[2,3-d]pyrimidin-4-amine 是一种杂环化合物,可抑制激酶和磷酸二酯酶等多种酶,对多种疾病具有潜在治疗活性。 | |||
T39509 |
DBCO-PEG3-amine
DBCO-PEG3-amine |
Others | Others |
DBCO-PEG3-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T39728 |
Amine-PEG3-Desthiobiotin
Amine-PEG3-Desthiobiotin |
Others | Others |
Amine-PEG3-Desthiobiotin is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T13601 |
CDD3506
1-TRITYL-1H-IMIDAZOL-4-AMINE |
P450 | Metabolism |
CDD3506 (1-TRITYL-1H-IMIDAZOL-4-AMINE) 能够诱导肝CYP3A 的活动,增强高密度脂蛋白胆固醇的水平。 | |||
T39454 |
Methyltetrazine-PEG4-amine hydrochloride
Methyltetrazine-PEG4-amine hydrochloride |
Others | Others |
Methyltetrazine-PEG4-amine (hydrochloride) is a PEG-based PROTAC linker utilized for PROTAC synthesis. | |||
T36259 |
Lenalidomide 4'-PEG3-amine
Lenalidomide 4'-PEG3-amine |
Others | Others |
Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG3 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license. | |||
T36258 |
Lenalidomide 4'-PEG2-amine
Lenalidomide 4'-PEG2-amine |
Others | Others |
Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG2 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license. | |||
T38833 |
S-acetyl-PEG4-amine
S-acetyl-PEG4-amine |
Others | Others |
S-acetyl-PEG4-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T36257 |
Lenalidomide 4'-PEG1-amine
Lenalidomide 4'-PEG1-amine |
Others | Others |
Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG1 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license. | |||
T39387 |
Xanthine amine congener dihydrochloride
XAC dihydrochloride,Xanthine amine congener dihydrochloride |
Others | Others |
Xanthine amine congener dihydrochloride (XAC dihydrochloride), a potent antagonist for both Adenosine A1 and A2 receptors, exhibits IC50 values of 1.8 nM for A1 and 114 nM for A2 receptors. Additionally, it functions as a convulsant agent in mouse models. | |||
T35470 |
A 410099.1 amide-PEG2-amine
A 410099.1 amide-PEG2-amine |
Others | Others |
Functionalized IAP ligand for PROTAC research and development; incorporates an IAP ligand plus a short amide-PEG linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license. | |||
T36279 |
VH 032 amide-alkylC3-amine
VH 032 amide-alkylC3-amine |
Others | Others |
Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl C3 linker and terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license. | |||
T36281 |
VH 032 amide-alkylC5-amine
VH 032 amide-alkylC5-amine |
Others | Others |
Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 13 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license. | |||
T36249 |
Thalidomide 4'-ether-PEG3-amine
Thalidomide 4'-ether-PEG3-amine |
Others | Others |
Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a short PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Thalidomide - linker 11 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license. | |||
T35473 |
A 410099.1 amide-PEG5-amine
A 410099.1 amide-PEG5-amine |
Others | Others |
Functionalized IAP ligand for PROTAC research and development; incorporates an IAP ligand plus an amide-PEG5 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license. | |||
T35471 |
A 410099.1 amide-PEG3-amine
A 410099.1 amide-PEG3-amine |
Others | Others |
Functionalized IAP ligand for PROTAC research and development; incorporates an IAP ligand plus a short amide-PEG linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license. | |||
T36276 |
Thalidomide 4'-oxyacetamide-alkylC8-amine
Thalidomide 4'-oxyacetamide-alkylC8-amine |
Others | Others |
Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Thalidomide amide-alkylC8-amine PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license. | |||
T36273 |
VH 101 phenol-alkylC4-amine
VH 101 phenol-alkylC4-amine |
Others | Others |
Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC4 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license. | |||
T35472 |
A 410099.1 amide-PEG4-amine
A 410099.1 amide-PEG4-amine |
Others | Others |
Functionalized IAP ligand for PROTAC research and development; incorporates an IAP ligand plus an amide-PEG4 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license. | |||
T39838 |
(S,R,S)-AHPC-C7-amine
VH032-C7-amine,(S,R,S)-AHPC-C7-amine |
Others | Others |
(S,R,S)-AHPC-C7-amine, also known as VH032-C7-amine, is a chemically synthesized conjugate that functions as an E3 ligase ligand-linker. This compound combines the VH032-based VHL ligand with a specific linker designed for the degradation of estrogen-related receptor α (ERRα) PROTAC. | |||
T36274 |
VH 101 phenol-alkylC6-amine
VH 101 phenol-alkylC6-amine |
Others | Others |
Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC6 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license. | |||
T36267 |
VH 032 amide-PEG4-amine
VH 032 amide-PEG4-amine |
Others | Others |
Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 2 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN1444 |
Bis(dihydrochelerythrinyl)amine
bis[6-(5,6-dihydrochelerythrinyl)]amine |
Antifection | Microbiology/Virology |
BIS-[6-(5,6-dihydro-chelerythrinyl)] ether shows strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus (MRSA). | |||
TN1243 |
3-Aminocoumarin
3-Amino-2-benzopyrone,3-aminochromen-2-one,Coumarin amine |
Others | Others |
3-Aminocoumarin (3-aminochromen-2-one) 是金属配合物的关键中间体。 | |||
TN7191 |
4-Amino-5-Bromopyrrolo[2,3-D]Pyrimidine
4-氨基-5-溴吡咯并[2,3-D]嘧啶,5-bromo-1H-pyrrolo[2,3-d]pyrimidin-4-amine,5-bromo-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
Others | Others |
4-Amino-5-Bromopyrrolo[2,3-D]Pyrimidine (5-bromo-1H-pyrrolo[2,3-d]pyrimidin-4-amine) 是一种海洋来源的天然产物,存在于Echinodictyum sp.。 | |||
TN7137 |
2-Isobutoxyaniline
(2-isobutoxyphenyl)amine,2-(2-甲基丙氧基)苯胺,2-(2-methylpropoxy)aniline |
Others | Others |
2-Isobutoxyaniline ((2-isobutoxyphenyl)amine) 是一种海洋来源的天然产物,存在于 Brevibacterium sp.。 | |||
TN7193 |
2,4,6-Triphenylaniline
2,4,6-Triphenyl-anilin,2,4,6-三苯基苯胺,5'-Phenyl-[1,1':3',1''-terphenyl]-2'-amine |
Others | Others |
2,4,6-Triphenylaniline (5'-Phenyl-[1,1':3',1''-terphenyl]-2'-amine) 是一种海洋来源的天然产物,存在于Alternaria longipes。 | |||
T13487 |
1-Methylhistamine
2-(1-Methyl-1H-imidazol-4-yl)ethan-1-amine |
Others | Others |
2-(1-Methyl-1H-imidazol-4-yl)ethan-1-amine is a histamine metabolite. | |||
T4895 |
Pentane-1,5-diamine dihydrochloride
5-diamine dihydrochloride,Cadaverine dihydrochloride,1,5-戊二胺盐酸盐,Pentane-1 |
Endogenous Metabolite | Metabolism |
Pentane-1,5-diamine dihydrochloride (Cadaverine dihydrochloride) 是内源性代谢产物的一种。 | |||
T7851 |
Tyramine hydrochloride
盐酸酪胺,酪胺盐酸盐 |
Others; Endogenous Metabolite | Metabolism; Others |
Tyramine hydrochloride 是一种氨基酸,有助于调节血压。其中 Tyramine 天然存在于体内,并存在于某些食物中。 | |||
T0965 |
Histamine
Ergamine,组胺 |
5-HT Receptor; Endogenous Metabolite; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience |
Histamine (Ergamine) 是通过组胺的酶促脱羧衍生的胺。它是一种强大的胃分泌兴奋剂、支气管平滑肌的收缩剂、血管扩张剂以及中枢作用的神经递质。 | |||
T1045 |
Trimipramine maleate
Surmontil maleate,马来酸三甲丙咪嗪,三甲丙咪嗪马来酸盐 |
Dopamine Receptor; 5-HT Receptor; Antibacterial; Adrenergic Receptor; Norepinephrine; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience |
Trimipramine maleate (Surmontil maleate) 是一种 5-HT 受体拮抗剂,对 5-HT1C、5-HT2和 5-HT1A 受体的 pKi 值分别为 6.39、8.10和 4.66。 | |||
T4710 |
3-Methoxytyramine hydrochloride
3-O-methyl Dopamine hydrochloride,3-O-methyl Dopamine hydrochloride),3-O-甲基多巴胺盐酸盐 |
Others; Endogenous Metabolite; Drug Metabolite | Metabolism; Others |
3-Methoxytyramine hydrochloride (3-O-methyl Dopamine hydrochloride) 是多巴胺的无活性代谢物,能够活化痕量胺相关受体1 。 | |||
T41245 |
Trimethylamine N-oxide
|
Reactive Oxygen Species; NOD-like Receptor (NLR); TGF-beta/Smad | Immunology/Inflammation; Metabolism; NF-κB; Stem Cells |
Trimethylamine N-oxide (TMAO) 是由胆碱、甜菜碱和肉碱通过肠道微生物代谢产生的一种无色氧化胺,积聚在海洋动物的组织中,可预防尿素对蛋白质的破坏作用。Trimethylamine N-oxide 通过激活 ROS/NLRP3 炎性体诱导炎症,可诱导纤维细胞的分化和心脏纤维化。 | |||
T37341 |
N-Acetyltyramine
|
Antibacterial | Microbiology/Virology |
N-Acetyltyramine 是一种群体感应抑制剂,由溶藻弧菌 M3-10 产生。N-Acetyltyramine 可以抑制C. violaceumATCC 12472 的群体感应。它可以逆转阿霉素耐药白血病 P388 细胞的耐药性。 | |||
TN1970 |
N-trans-p-coumaroyloctopamine
N-p-Coumaroyloctopamine,N-对香豆酰真蛸胺,p-coumaroylnoradrenaline |
Others | Others |
N-trans-p-coumaroyloctopamine (p-coumaroylnoradrenaline) 来源于马铃薯的块茎组织。 | |||
T4708 |
D-N-Acetylgalactosamine
D-GalNAc,N-Acetyl-D-galactosamine,N-乙酰-D-半乳糖胺 |
Others; Endogenous Metabolite | Metabolism; Others |
D-N-Acetylgalactosamine (N-Acetyl-D-galactosamine) 是脑杂多糖(糖蛋白)的重要组成部分。 | |||
T5S0803 |
Columbamine
非洲防己碱,Columbamin,Dehydroisocorypalmine |
Others | Others |
Columbamine (Columbamin) 是一种从植物中提取的季异喹啉生物碱。 | |||
T14865 |
Carboprost tromethamine
|
Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
Carboprost tromethamine 是合成的前列腺素 F2α的15-甲基类似物,能有效促进子宫的规律收缩,显着减少产中及产后出血量。 | |||
T3364 |
Veratramine
NSC17821,黎芦碱,NSC23880,藜芦胺 |
Sodium Channel | Membrane transporter/Ion channel |
Veratramine (NSC-23880) 是一种信号转导抑制剂,可作用于肿瘤。 | |||
T4874 |
Thiamine pyrophosphate
Cocarboxylase,焦磷酸硫胺素,Aneurinepyrophosphoric acid,Thiamine pyrophosphate chloride |
Endogenous Metabolite | Metabolism |
Thiamine pyrophosphate (Cocarboxylase) 是维生素 B1 的辅酶形式,是丙酮酸脱氢酶复合物和酮戊二酸脱氢酶复合物的必需中间体,能够用于研究评估生物系统中的脱羧机制。 | |||
T4514 |
N-Acetyl-D-Glucosamine
N-乙酰-D-氨基葡萄糖,NAG,N-Acetyl-2-amino-2-deoxyglucose,Marine Sweet,N-Acetyl-2-amino-2-deoxy-D-glucose,N-乙酰氨基葡萄糖,GlcNAc |
Endogenous Metabolite | Metabolism |
N-Acetyl-D-Glucosamine (NAG) 是葡萄糖的单糖衍生物。 | |||
T8048 |
Diphenylamine Hydrochloride
|
Others | Others |
Diphenylamine hydrochloride 分离自 coriander ,具有抗氧化作用。在农业中,它可用作杀菌剂及抗菌剂;在工业中,它可用作抗氧化剂及染料媒染剂。 | |||
T4881 |
Phosphorylethanolamine
O-Phosphorylethanolamine,乙醇胺磷酸酯 |
Others; Endogenous Metabolite | Metabolism; Others |
Phosphorylethanolamine (O-Phosphorylethanolamine) 是磷脂代谢的一种磷酸单酯代谢物。Phosphorylethanolamine 是磷脂合成的前体,也是磷脂分解的产物。与其他器官相比,大脑中磷酸单酯的含量要高得多。在大脑发育过程中,磷单酯通常在神经增生期间升高。这也与大脑发育过程中正常的程序性细胞死亡和突触修剪的发生相吻合。这些发现与磷酸单酯在膜生物合成中的作用是一致的。Phosphorylethanolamine 与抑制性神经递质GABA和GABAB受体部分激动剂 3-氨基丙基膦酸具有很强的结构相似性。Phosphorylethanolamine 是一种磷单酯,在阿尔茨海默病患者的大脑中减少。 | |||
T0647 |
Tryptamine
|
Dehydrogenase; 5-HT Receptor; Endogenous Metabolite; TRP/TRPV Channel | GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Neuroscience |
Tryptamine 是一种在动物、植物和真菌中发现的单胺生物碱。它含有吲哚环结构,结构类似于色氨酸。在哺乳动物的大脑中发现了微量这种物质,并被认为是一种神经递质或神经调节剂。 | |||
T4860 |
5-Hydroxytryptamine creatinine sulfate monohydrate
Serotonin creatinine sulfate monohydrate,5-Hydroxytryptamine creatinine sulfate complex,5-五羟色胺肌酸酐 |
Others; Endogenous Metabolite | Metabolism; Others |
5-Hydroxytryptamine creatinine sulfate monohydrate (Serotonin creatinine sulfate monohydrate) 是内源性代谢产物的一种。 | |||
T4S1619 |
L-Hyoscyamine sulfate
Hyoscyamine sulfate hydrate,Levsin Sulfate,Hyoscyamine Sulphate,硫酸天仙子胺水合物,L-莨菪碱硫酸盐 |
AChR | Neuroscience |
L-Hyoscyamine sulfate (Levsin Sulfate) 是来自山莨菪的一种托烷生物碱,是竞争性的毒蕈碱受体拮抗剂。它是 Atropine 的左旋异构体。 | |||
T41358 |
2-Hydroxybenzylamine
|
Others | Others |
2-Hydroxybenzylamine 是一种有效的 IsoLG 小分子清除剂,可将活性物质作为惰性加合物螯合。 2-Hydroxybenzylamine 可用于通过减少具有天然生物分子的 IsoLG 加合物来减少心房颤动消融后心房颤动和其他心房心律失常的早期复发。 | |||
T8016 |
N-Methylbenzylamine
N-甲基苄胺,N-Benzylmethylamine |
Others | Others |
N-Methylbenzylamine (N-Benzylmethylamine) 是一种存在于胡萝卜中的苯基甲基胺化合物,可用作潜在的生物标记。 | |||
T0983 |
Penicillamine
青霉胺,d-penicillamin,Dimethyl Cysteine,D-青霉胺,Artamine,D-(-)-Penicillamine |
Antibiotic | Microbiology/Virology |
Penicillamine (Artamine) 是一种 penicillin 的代谢降解产物,是一种螯合剂,可作用于威尔逊氏病。 | |||
T5543 |
TriacetonaMine
四甲基哌啶酮,Odoratine,tempidon,tmpone,Vincubine,2,2,6,6-Tetramethyl-4-piperidinone |
Others | Others |
TriacetonaMine (Vincubine) 是一种合成医药产品、农药和聚合物光稳定剂的中间体。它是热解油的主要组分。它是植物和真菌提取物的人工制品,使用丙酮和氢氧化铵,或在分离过程的不同步骤中天然出现铵盐。 | |||
TN6786 |
O-Desmethyl Galanthamine
Sanguinine,O-去甲基加兰他敏 |
AChE | Neuroscience |
O-Desmethyl Galanthamine (Sanguinine) 是一种加兰他敏型生物碱,是一种乙酰胆碱酯酶 (AChE) 抑制剂,其IC50=1.83 μM。 | |||
T41031 |
Protamine sulfate
|
Thrombin | Proteases/Proteasome |
Protamine sulfate是一种多阳离子肽类,作为一种抗肝素剂。该化合物能中和肝素的抗凝作用并增强脂质介导的基因转移。 | |||
T5238 |
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine
1,2-Dipalmitoyl-sn-glycero-3-PE,L-磷脂酰乙醇胺,1,2-Dipalmitoyl-sn-glycerol-3-Phosphoethanolamine,1,2-DPPE |
Others; Endogenous Metabolite | Metabolism; Others |
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE) 是内源性代谢产物的一种。 | |||
T35455 |
N-Nitrosodiethylamine
Diethylnitrosamine,NDEA |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
N-Nitrosodiethylamine (NDEA) 是致癌物质二烷基硝胺。它主要存在于水、烟草烟雾、腌制食品、油炸食品以及许多酒精饮料中。它与 DNA 修复/复制相关的核酶的变化相关。 | |||
T5249 |
1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine
1,2-DSPE,1,2-二硬酯酰-SN-甘油-3-磷酰乙醇胺,1,2-Distearoyl-sn-glycero-3-phosphoethan |
Others; Endogenous Metabolite | Metabolism; Others |
1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (1,2-DSPE) 是一种磷脂酸乙醇胺 (PE) ,能够用于合成脂质体。 | |||
T8304 |
Anisodamine Hydrobromide
6-Hydroxyhyoscyamine,氢溴酸山莨菪碱 |
Adrenergic Receptor; AChR | GPCR/G Protein; Neuroscience |
Anisodamine Hydrobromide (6-Hydroxyhyoscyamine) 是来自颠茄的一种生物碱,具有抗氧化、抗炎活性。它也是一种非亚型的选择性毒蕈碱和烟碱类胆碱受体拮抗剂。 | |||
TN3497 |
Benzylamine hydrochloride
|
Others | Others |
Benzylamine hydrochloride 由卞胺和盐酸制的, 可用于治疗晕动病和蛔虫病,具有止吐特性。 | |||
T2825 |
Cyclopamine
环巴胺,11-Deoxojervine |
Hedgehog/Smoothened; Endogenous Metabolite; Smo | GPCR/G Protein; Metabolism; Stem Cells |
Cyclopamine (11-Deoxojervine) 是Hedgehog 通路的拮抗剂,细胞实验中IC50=46 nM。它还是选择性Smo 抑制剂。 | |||
T0469 |
Octopamine hydrochloride
章鱼胺盐酸盐,(±)-p-Octopamine hydrochlorid,(+,-)-Octopamine HCl,章胺盐酸盐 |
Dopamine Receptor; Endogenous Metabolite; Adrenergic Receptor | GPCR/G Protein; Metabolism; Neuroscience |
Octopamine hydrochloride ((±)-p-Octopamine hydrochlorid) 是一种与去甲肾上腺素结构相关的生物单胺类物质,在无脊椎动物中起着神经调节剂、神经激素和神经递质的作用。它对转染人 alpha2-肾上腺素受体(ARs)的中国仓鼠卵巢细胞 α2-ARs 有刺激作用。它提高糖原分解、糖酵解、糖异生、摄氧量和门脉灌注压。 | |||
T1354 |
N-Acetyl-5-hydroxytryptamine
Normelatonin,N-乙酰-5-羟色胺,O-Demethylmelatonin,N-Acetylserotonin |
Trk receptor; Endogenous Metabolite | Metabolism; Tyrosine Kinase/Adaptors |
N-Acetyl-5-hydroxytryptamine (O-Demethylmelatonin) 是褪黑激素的直接前体,能够有效激活TrkB 受体。 | |||
TN1968 |
N-Feruloyloctopamine
N-Feruloyloctopamine,N-阿魏酰章鱼胺 |
p38 MAPK; Akt | Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling |
N-Feruloyloctopamine 是从木本曼陀罗提取的一种天然产物,有抗氧化作用,可显著降低Akt 和p38 MAPK 磷酸化水平。 | |||
T2S2335 |
Dehydroevodiamine
DHED,去氢吴茱萸碱 |
Others; NF-κB; COX; PGE Synthase; NO Synthase | Immunology/Inflammation; Neuroscience; NF-κB; Others |
Dehydroevodiamine (DHED) 是从吴茱萸中分离出的一种喹唑啉生物碱,可抑制 LPS 诱导的小鼠巨噬细胞中iNOS、COX-2、PGE2和NF-κB 的表达,对豚鼠心室肌细胞具有抗心律失常作用。 | |||
TN7232 |
Pegamine
|
||
pegamine 是一种在Peganum harmala 和Peganum nigellastrum 中发现的天然产品,是一种新型的生物碱。 | |||
T0894 |
Thiamine hydrochloride
盐酸硫胺素,Vitamin B1,Vitamin B1 hydrochloride,Thiamine HCl,盐酸硫胺(维生素B1),Thiamine chloride hydrochloride |
Apoptosis; HBV; Endogenous Metabolite | Apoptosis; Metabolism; Microbiology/Virology |
Thiamine hydrochloride (Vitamin B1) 是一种必需的微量营养素,是许多中枢代谢酶的辅因子。 | |||
T4925 |
Thiamine monophosphate chloride (dihydrate)
Thiamine monophosphate chloride dihydrat,胺氯化亚磷酸酯,Aneurine monophosphate chloride |
Others; Endogenous Metabolite | Metabolism; Others |
Thiamine monophosphate chloride dihydrate (Aneurine monophosphate chloride) 是内源性代谢产物的一种。 | |||
T0330 |
Diphenhydramine hydrochloride
盐酸苯海拉明,Diphenhydramine HCl,DPH |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Diphenhydramine hydrochloride (DPH) 是一种组胺 H1 拮抗剂,用作镇咳药和止吐药。它还用于治疗瘙痒和皮肤病、过敏反应、抗帕金森病、催眠药和普通感冒制剂的成分。 | |||
T22327 |
Ethanolamine hydrochloride
甲基氧氯酸,2-Aminoethanol hydrochloride,乙醇胺盐酸盐 |
Others | Others |
Ethanolamine hydrochloride (2-Aminoethanol hydrochloride) 是一种具有氨气味的粘性、吸湿性氨基醇,广泛分布于生物组织中,是卵磷脂的一种成分。 | |||
T21095 |
4-Hydroxybenzylamine
4-(Aminomethyl)phenol,4-HOBA,4-羟基苄胺 |
Endogenous Metabolite | Metabolism |
4-Hydroxybenzylamine (4-HOBA) 是内源性代谢产物的一种。 | |||
T4238 |
Glycocyamine
乙酸胍,2-Guanidinoacetic acid,Guanidoacetic acid |
Others; Endogenous Metabolite | Metabolism; Others |
Glycocyamine (2-Guanidinoacetic acid) 是一种肌酸的前体,能够为鸟类的体内平衡提供能量,也能够成为食用精氨酸的替代物。 | |||
TN6457 |
N-trans-caffeoyltyramine
Trans-N-Caffeoyltyramine,N-(E)-Caffeoyl-lambda-tyramine,N-cis-Caffeoyltyramine,Typheramide |
Immunology/Inflammation related | Immunology/Inflammation |
N-trans-caffeoyltyramine (Trans-N-Caffeoyltyramine) 是炎症反应的调节剂,可用于慢性炎症性疾病治疗的研究。 | |||
T13681 |
Epi-galantamine
|
AChE | Neuroscience |
Epi-galantamine 是 Galantamine 的非对映异构体,是从高加索雪花莲的鳞茎和花朵中分离出来的生物碱。它能够抑制AChE,EC50=45.7 μM 。 | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00379 |
AOC3 Protein, Human, Recombinant (hFc)
SSAO,AOC3,Membrane primary amine oxidase,Copper |
Human | HEK293 Cells |
Membrane primary amine oxidase(AOC3), also known as vascular adhesion protein (VAP-1) and HPAO, this protein is a member of the semicarbazide-sensitive amine oxidase (SSAO) family. VAP-1 is a type 1 membrane-bound glycoprotein that has a distal adhesion domain and an enzymatically active amine oxidase site outside of the membrane, VAP-1 has adhesive properties, functional monoamine oxidase activity, and possibly plays a role in glucose handling, leukocyte trafficking, and migration during inflam... | |||
TMPJ-00380 |
AOC3 Protein, Human, Recombinant (His)
Membrane primary amine oxidase,HPAO,VAP-1,Semicarba... |
Human | HEK293 Cells |
Vascular adhesion protein-1(VAP-1) is a copper amine oxidase with a topaquinone cofactor.VAP-1 is a type II integral membrane protein, but a soluble form of the enzyme is present in human serum, and its level increases in diabetes and some inflammatory liver diseases. VAP-1 catalyzes the oxidative deamination of small primary amines such as methylamine, benzylamine, and aminoacetone in a reaction that produces an aldehyde, ammonia, and H2O2. VAP-1 vascular expression is regulated at sites of inf... | |||
TMPY-00140 |
ABP1/AOC1 Protein, Human, Recombinant (His)
amine oxidase, copper containing 1,DAO,ABP1,ABP,KAO... |
Human | HEK293 Cells |
Amine oxidase copper-containing 1 (AOC1; formerly known as amiloride-binding protein 1) is a secreted glycoprotein that catalyzes the degradation of putrescine and histamine. Polyamines and their diamine precursor putrescine are ubiquitous to all organisms and fulfill pivotal functions in cell growth and proliferation. That the Wilms tumor protein, WT1, which is necessary for normal kidney development, activates transcription of the AOC1 gene. Expression of a firefly luciferase reporter under co... | |||
TMPH-00926 |
MAOB Protein, Human, Recombinant (His)
Amine oxidase [flavin-containing] B,Monoamine |
Human | E. coli |
MAOB Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPK-00371 |
PSMA Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
NAALADase I,FOLH1,GCPIImGCP,FGCP,GCP2,PSM,mGCP,NAALAdase,FOL... |
Mouse | HEK293 Cells |
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein (Primary Amine Labeling), Mouse, Recombinant (His), Bi... | |||
TMPK-00482 |
TSLP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
thymic stromal lymphopoietin,TSLP |
Cynomolgus | HEK293 Cells |
Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells. TSLP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated is expressed in... | |||
TMPK-00522 |
PSMA Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
PSMAFGCP,PSM,NAALAdase,NAALADase I,FOLHNAALADase I,GCPIImGCP... |
Cynomolgus | HEK293 Cells |
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His... | |||
TMPK-00096 |
FGF-10 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated
FGF-10,KGF2 |
Human | E. coli |
Fibroblast growth factor 10 (FGF10) regulates multiple stages of structural lung morphogenesis, cellular differentiation, and the response to injury. As a driver of lung airway branching morphogenesis, FGF10 signaling defects during development lead to neonatal lung disease. Lung diseases impact patients across the lifespan, from infants in the first minutes of life through the aged population. Congenital abnormalities of lung structure can cause lung disease at birth or make adults more suscept... | |||
TMPK-00341 |
ALCAM Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
ALCAM,KG-CAM,MEMD,CD166,CD6L |
Human | HEK293 Cells |
Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression promote BM formation in NSCLC through increased tumor cell dissemination and interaction with the brain endothelial cells. Therefore, ALCAM could be targeted to reduce the occurrence of BM. ALCAM Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed ... | |||
TMPK-01210 |
DLL3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
DLL3,SCDO1δ3,SCDO1,Pudgy,δ3,SCDO1delta3,Delta3 |
Human | HEK293 Cells |
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with N-His tag. The predicted mo... | |||
TMPK-01238 |
PADI4 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
PDI5,Protein-arginine deiminase type-4,HL-60,PAD4,HL-60 PAD,... |
Human | E. coli |
Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes. PADI4 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinyla... | |||
TMPK-00410 |
AXL Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
ARK,EC 2.7.10.1,EC 2.7.10,Axl,JTK11,AXL oncogene,UFO,AI32364... |
Human | HEK293 Cells |
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein (Primary Amine Labeling), Human, Rec... | |||
TMPK-00204 |
FGL1 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
Hepassocin,Lag3 ligand,HP-041,LFIRE-1,HFREP1,FGL1,HFREP-1,FG... |
Human | HEK293 Cells |
Fibrinogen-like protein 1 (FGL-1) is a protein that is structurally related to fibrinogen. In humans, FLG-1 is encoded by the FGL1 gene.Fibrinogen-like protein 1 is a member of the fibrinogen family of proteins, which also includes fibrinogen, fibrinogen-like protein 2, and clotting factors V, VIII, and XIII.Fibrinogen-like Protein 1 is a major immune inhibitory ligand of LAG-3. | |||
TMPK-00582 |
MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated
MASP1P1,MAP19,sMap,MASP-2 |
Rat | E. coli |
MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.7 kDa and the accession number is A2VCV7. | |||
TMPK-00406 |
TLR3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
IIAE2,TLR3,CD283 |
Human | HEK293 Cells |
TLR3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 78.7 kDa and the accession number is Q6PCD4. | |||
TMPK-00502 |
PADI4 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
PDI5,HL-60,PAD,PADI5,Protein-arginine deiminase type-4,HL60 ... |
Cynomolgus | E. coli |
Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes. PADI4 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biot... | |||
TMPK-00675 |
CD24 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated
MGC75043,FLJ43543,CD24 molecule,FLJ22950,CD 24,CD24A |
Cynomolgus | HEK293 Cells |
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers. CD24 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 30.2 kDa... | |||
TMPK-00100 |
CD7 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated
TP41,CD7,CD7 molecule,Tp40,LEU-9,GP40 |
Mouse | HEK293 Cells |
CD7, also known as Leu-9, is an approximately 40 kDa glycosylated and palmitoylated transmembrane protein in the immunoglobulin superfamily.CD7 is expressed on T cells, NK cells , myeloid progenitor cells, and CD19 B progenitor cells. Among CD8 T cells, the CD7-bright population preferentially contains naïve and memory cells, while more weak expressors are primarily effector cells. CD7 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells... | |||
TMPK-01224 |
CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
P130,BILL-cadherin,LI-cadherin,MGC138218,FLJ26931,CDH16,Cadh... |
Mouse | HEK293 Cells |
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant ... | |||
TMPK-01026 |
MSLN/Mesothelin Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
MPFSMRP,SMR,MSLN,CAK1,Mesothelin,MPF |
Mouse | HEK293 Cells |
MSLN/Mesothelin Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 35.2 kDa and the accession number is Q61468-1. | |||
TMPK-00300 |
CD5 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
T1,CD5,LEU1,CD5 antigen,CD5 molecule |
Mouse | HEK293 Cells |
CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; expressed in B-cell chronic lymphocytic leukemia and T-cell lymphoma. CD5 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 38.9 kDa and the accession number is P13379. | |||
TMPK-00006 |
CD24 Protein (Primary Amine Labeling), Human, Recombinant (mFc), Biotinylated
CD 24,CD24A,FLJ43543,CD24 molecule,MGC75043,FLJ22950 |
Human | HEK293 Cells |
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers. CD24 Protein (Primary Amine Labeling), Human, Recombinant (mFc), Biotinylated is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 29.5 kDa and ... | |||
TMPK-00076 |
IL-18 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated
白介素,IL-18,白细胞介素,IL18,IL-1F4,IL-1g,IL1F4,IL-1 gamma,Interleuk... |
Human | E. coli |
Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation. | |||
TMPK-00104 |
HMGB1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
HMG3,HMG-1,HMGB1,SBP-1,HMG1 |
Human | HEK293 Cells |
High-mobility group box 1 (HMGB1) is a ubiquitous nuclear protein that promotes inflammation when released extracellularly after cellular activation, stress, damage or death. HMGB1 operates as one of the most intriguing molecules in inflammatory disorders via recently elucidated signal and molecular transport mechanisms. Treatments based on antagonists specifically targeting extracellular HMGB1 have generated encouraging results in a wide number of experimental models of infectious and sterile i... | |||
TMPK-00664 |
GDF-15 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated
Placental TGF-beta,PTGFBPTGF-β,PLAB,MIC-1,GDF15,NAG-1,RG-1,P... |
Cynomolgus | HEK293 Cells |
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am... | |||
TMPK-00198 |
GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
MIC-1,PTGFBPTGF-β,GDF15,PTGF-β,GDF-15,PTGF-beta,Placental TG... |
Human | HEK293 Cells |
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am... | |||
TMPK-01397 |
MSLN/Mesothelin Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
MPFSMRP,Mesothelin,MPF,SMR,MSLN,CAK1 |
Cynomolgus | HEK293 Cells |
MSLN/Mesothelin Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 33 kDa and the accession number is A0A2K5TW94-1. | |||
TMPK-00937 |
CKAP4 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
p63,CLIMP-63,ERGIC-63 |
Human | E. coli |
Cytoskeleton-associated protein 4 (CKAP4) is located in the rough endoplasmic reticulum (ER) and plays an important role in stabilizing the structure of ER. Meanwhile, CKAP4 is also found to act as an activated receptor at the cell surface. CKAP4 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 53.66 kDa and the accession number is Q07065. | |||
TMPK-00005 |
CD24 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
CD24A,FLJ22950,CD24 molecule,CD 24,FLJ43543,MGC75043 |
Human | HEK293 Cells |
CD24 is a sialoglycoprotein expressed at the surface of most B lymphocytes and differentiating neuroblasts. It is also expressed on neutrophils and neutrophil precursors from the myelocyte stage onwards. The potential for targeting CD24 in cancer therapy seems promising, as CD24 is overexpressed in many human cancers. CD24 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 29.9 kDa and ... | |||
TMPK-00492 |
IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
Igifbp,Interleukin-18-binding protein,IL-18BP |
Cynomolgus | HEK293 Cells |
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy receptor, is frequently upregulated in diverse human and mouse tumours and limits the anti-tumour activity of IL-18 in mice. IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombi... | |||
TMPK-00231 |
Siglec-15 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
CD33 molecule-like 3,Siglec15,CD33L3,HsT1361,CD33 antigen-li... |
Mouse | HEK293 Cells |
Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates. Siglec-15 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylate... | |||
TMPK-00181 |
PD-1 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated
SLEB2,PD-1,PDCD1,PD1,CD279 |
Mouse | HEK293 Cells |
Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity. PD-1 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 42.9 kDa and the accessio... | |||
TMPK-01245 |
GDF-15 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated
RG-1,GDF15,Placental TGF-beta,GDF-15,PTGFBPTGF-beta,NAG-1,PT... |
Mouse | HEK293 Cells |
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am... | |||
TMPK-00720 |
Siglec-5 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
CD170,CD33 antigen-like 2,OBBP2,SIGLEC5,OB-BP2,CD33L2 |
Human | HEK293 Cells |
Group B Streptococcus (GBS) causes invasive infections in human newborns. the GBS β-protein attenuates innate immune responses by binding to sialic acid-binding immunoglobulin-like lectin 5 (Siglec-5), an inhibitory receptor on phagocytes.the polymorphism could influence the risk of prematurity among human fetuses of mothers colonized with GBS. This first functionally proven example of a paired receptor system in the Siglec family has multiple implications for regulation of host immunity. | |||
TMPY-04955 |
HER2/ERBB2 Protein, Human, Recombinant (His), Amine-Labeled Biotinylated
HER2,MLN 19,HERVW,NEU,ERVWE1,EGFR2,HERV-7q,ENV,ENVW,TKR1,HER... |
Human | HEK293 Cells |
HER2/ERBB2 Protein, Human, Recombinant (His), Amine-Labeled Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71 kDa and the accession number is P04626-1. | |||
TMPK-00081 |
FGF-7/KGF Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
FGF-7,成纤维细胞生长因子,HBGF-7,KGF |
Human | E. coli |
The expression patterns of mRNAs encoding Fibroblast Growth Factor-7 (FGF-7) and its high affinity receptor suggested that FGF-7 signaling may play a role in regulating ureteric bud growth.t Results of these studies demonstrate that the developing ureteric bud and mature collecting system of FGF-7-null kidneys is markedly smaller than wild type. FGF-7 levels modulate the extent of ureteric bud growth during development and the number of nephrons that eventually form in the kidney. | |||
TMPK-00169 |
OX40/TNFRSF4 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
IMD16,ACT-135,OX40 homologue,Ly-70, TXGP1L,TNFRSF4,OX40,OX40... |
Human | HEK293 Cells |
Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. OX40/TNFRSF4 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular wei... | |||
TMPK-00615 |
NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
CD335,NCR1,NKp46,NKP46FLJ99094,Ly94,MAR-1 |
Human | HEK293 Cells |
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells. NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular we... | |||
TMPK-00619 |
FcRH5/FcRL5 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
IFGP5,CD307,FCRH5MGC119593,FLJ00397,DKFZp667E2019,BXMAS1MGC1... |
Human | HEK293 Cells |
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. FcRH5/FcRL5 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 92.38 kDa and the accession number is AAK93971. | |||
TMPK-00154 |
CD40 Ligand Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
IMD3,TNFSF5IMD3,TRAP,CD40LIGM,CD40 Ligand,HIGM1,gp39,IGM,TNF... |
Human | HEK293 Cells |
CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells. CD40 Ligand Prote... | |||
TMPK-00763 |
Apolipoprotein E/APOE3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
APOE3,Apo-E,apolipo E,Apolipoprotein E,APOE |
Human | HEK293 Cells |
Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD). Apolipoprotein E/APOE3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated i... | |||
TMPK-00259 |
Latent TGF beta 3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
TGF-beta3,TGFβ,TGF-β,TGF-β3,TGFB3,ARVD,TGFβ3,转化生长因子,Latent T... |
Human | HEK293 Cells |
Transforming growth factor-betas (TGF-βs) are multifunctional cytokines that have been implicated in the regulation of a broad range of biological processes, including cell proliferation, cell survival, and cell differentiation. And transforming growth factor beta3 (TGFbeta3) is a key protein involved in scar-free healing observed in embryos. Latent TGF beta 3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with N-His tag. The predi... | |||
TMPK-00142 |
APRIL/TNFSF13 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
TALL-2,CD256,TRDL1,APRILFLJ57090,APRIL,TNFSF13,2310026N09Rik... |
Human | HEK293 Cells |
The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily receptors TACI and BCMA, while BAFF additionally functions through BAFF R. APRIL/TNFSF13 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecular weight is 49.9 kDa and... | |||
TMPK-00197 |
GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (H202D, hFc), Biotinylated
Placental TGF-β,GDF15,RG-1,MIC-1,PTGFB,PTGF-beta,PDF,PTGF-β,... |
Human | HEK293 Cells |
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am... | |||
TMPK-00951 |
CDH17 Domain 5-7 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
FLJ26931,CDH16,LI-cadherin,MGC138218,cadherin-16,Cadherin-17... |
Human | HEK293 Cells |
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 5-7 Protein (Primary Amine Labeling), Human, R... | |||
TMPK-00054 |
GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
TL6,GITR Ligand,TNFSF18,AITRL,GITRL |
Human | HEK293 Cells |
Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept. GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated is expressed in HEK293 mammalian cells with... | |||
TMPK-01136 |
CD3 epsilon/CD3e Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
TCRE,CD3e,CD3-epsilon,FLJ18683,CD3-ε,CD3E/CD3 ε,IMD18,T3E |
Cynomolgus | HEK293 Cells |
CD3E, is a single-pass type I membrane protein.CD3 (cluster of differentiation 3) T cell co-receptor helps to activate both the cytotoxic T cell (CD8 naive T cells) and also T helper cells (CD4 naive T cells). It consists of a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. CD3 epsilon/CD3e Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells ... | |||
TMPK-00080 |
CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
CD27-L,CD70 molecule,TNFSF7G,CD70,CD27LG,CD27 Ligand,TNFSF7,... |
Human | HEK293 Cells |
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with N-His tag. The predicted molecula... | |||
TMPK-00321 |
IL-2 R beta/CD122 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
IL-2 R beta,IL-2R subunit beta,IL-2 R β,IL-2R subunit β,IL-1... |
Cynomolgus | HEK293 Cells |
IL-2 R beta/CD122 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 25.6 kDa and the accession number is Q38J85. | |||
TMPK-00662 |
PD-L1 Protein (Primary Amine Labeling), Cynomolgus/Rhesus macaque, Recombinant (His), Biotinylated
PDCD1LG1,B7-H1,B7H1,CD274,B7-H,PDCD1L1,PD-L1B7 homolog 1,PDL... |
Cynomolgus,Rhesus | HEK293 Cells |
B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1 Protein (Primary Amine Labeling), Cynomolgus/Rhesus macaque, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His t... | |||
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Cat. No. | Product Name | Target | Signaling Pathways |
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TMIH-0238 |
Florfenicol Amine-d3
|
||
Florfenicol Amine-d3 是 Florfenicol Amine 的氘代化合物。Florfenicol Amine 的 CAS 号为 108656-33-3。 | |||
TMIH-0247 |
Furfuryl-d5-amine HCl
|
||
Furfuryl-d5-amine HCl 是 Furfuryl-amine HCl 的氘代化合物。Furfuryl-amine HCl 的 CAS 号为 1219799-26-4。 | |||
T64769 |
Propan-d7-2-amine hydrochloride
|
||
Propan-d7-2-amine hydrochloride 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64769。 | |||
TMIJ-0106 |
Isopropyl-d7-amine HCl
|
||
Isopropyl-d7-amine HCl 是 Isopropyl-amine HCl 的氘代化合物。Isopropyl-amine HCl 的 CAS 号为 15572-56-2。 | |||
TMIH-0028 |
2-(1-(methyl-d3)-1H-imidazol-4-yl)ethan-1-amine 2HCl
1-Methylhistamine-d3 Dihydrochloride |
||
2-(1-(methyl-d3)-1H-imidazol-4-yl)ethan-1-amine 2HCl 是 2-(1-(methyl)-1H-imidazol-4-yl)ethan-1-amine 2HCl 的氘代化合物。2-(1-(methyl)-1H-imidazol-4-yl)ethan-1-amine 2HCl 的 CAS 号为 6481-48-7。1-Methylhistamine dihydrochloride 是组胺代谢物。 | |||
TMIH-0184 |
Desipramine-d3 HCl
|
||
Desipramine-d3 HCl 是 Desipramine HCl 的氘代化合物。Desipramine HCl 的 CAS 号为 58-28-6。Desipramine hydrochloride 是一种二苯并氮杂类衍生物三环类抗抑郁药,可作为选择性去甲肾上腺素再摄取抑制剂。 它还显示出较弱的 5-羟色胺再摄取抑制、α1 阻断、抗组胺和抗胆碱能作用。 | |||
T10842L |
Clomipramine D3 hydrochloride
|
Others | Others |
Clomipramine D3 hydrochloride is the deuterium-labeled Clomipramine. Clomipramine is a serotonin transporter, norepinephrine transporter dopamine transporter blocker (Ki: 0.14, 54 and 3 nM). | |||
T10842 |
Clomipramine D3
氯米帕明 D3 |
Others | Others |
Clomipramine D3 is the deuterium-labeled Clomipramine. Clomipramine is a serotonin transporter, norepinephrine transporter dopamine transporter blocker (Ki: 0.14, 54 and 3 nM). | |||
TMIH-0401 |
Octopamine-d3
|
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Octopamine-d3 是 Octopamine 的氘代化合物。 | |||
TMIH-0484 |
Ractopamine-d6 Hydrochloride (Mixture of Diastereomers)
|
||
Ractopamine-d6 Hydrochloride (Mixture of Diastereomers) 是 Ractopamine Hydrochloride (Mixture of Diastereomers) 的氘代化合物。 | |||
TMIJ-0440 |
N-Methyltryptamine-d3
|
||
N-Methyltryptamine-d3 是 N-Methyltryptamine 的氘代化合物。N-Methyltryptamine 的 CAS 号为 61-49-4。 | |||
TMID-0243 |
(±)-sibutramine hydrochloride-d6 monohydrate
|
||
(±)-sibutramine hydrochloride-d6 monohydrate 是 (±)-sibutramine hydrochloride monohydrate 的氘代化合物。(±)-sibutramine hydrochloride monohydrate 的 CAS 号为 125494-59-9。 | |||
TMID-0287 |
Galanthamine-O-methyl-d3
|
||
Galanthamine-O-methyl-d3 是 Galanthamine-O-methyl 的氘代化合物。Galanthamine-O-methyl 的 CAS 号为 357-70-0。Galanthamine 是一种乙酰胆碱酯酶抑制剂,IC50为 500 nM。 | |||
TMIH-0465 |
Pyridoxamine-d3 dihydrochloride
|
||
Pyridoxamine-d3 dihydrochloride 是 Pyridoxamine dihydrochloride 的氘代化合物。 | |||
TMIH-0482 |
Ractopamine-d5 Hydrochloride
|
||
Ractopamine-d5 Hydrochloride 是 Ractopamine Hydrochloride 的氘代化合物。 | |||
TMID-0186 |
Fluvoxamine-d3 Maleate
|
||
Fluvoxamine-d3 Maleate 是 Fluvoxamine Maleate 的氘代化合物。Fluvoxamine Maleate 的 CAS 号为 61718-82-9。Fluvoxamine maleate 是一种5-羟色胺再吸收抑制剂,有抗抑郁作用。 | |||
TMIJ-0377 |
Thiamine Hydrochloride-13C4
|
||
Thiamine Hydrochloride-13C4 是 Thiamine Hydrochloride 的 13C 的标记化合物。Thiamine Hydrochloride 的 CAS 号为 67-03-8。Thiamine hydrochloride 是一种必需的微量营养素,是许多中枢代谢酶的辅因子。 | |||
TMIJ-0494 |
Higenamine-d4 HCl
|
||
Higenamine-d4 HCl 是 Higenamine HCl 的氘代化合物。Higenamine HCl 的 CAS 号为 11041-94-4。Higenamine hydrochloride 是一种 β2-AR 激动剂,是用于心力衰竭相关研究的中药乌头的关键成分,具有抗凋亡活性。 | |||
TMID-0020 |
N-Nitrosodimethylamine-d6
|
||
N-Nitrosodimethylamine-d6 是 N-Nitrosodimethylamine 的氘代化合物。N-Nitrosodimethylamine 的 CAS 号为 62-75-9。 | |||
TMID-0019 |
Ractopamine-d3 hydrochloride
|
||
Ractopamine-d3 hydrochloride 是 Ractopamine hydrochloride 的氘代化合物。Ractopamine hydrochloride 的 CAS 号为 90274-24-1。 | |||
TMIH-0481 |
Ractopamine-d5
|
||
Ractopamine-d5 是 Ractopamine 的氘代化合物。Ractopamine 的 CAS 号为 97825-25-7。 | |||
TMID-0259 |
1,4-Butane-2,2,3,3-d4-diamine 2HCl
|
||
1,4-Butane-2,2,3,3-d4-diamine 2HCl 是 1,4-Butane-diamine 2HCl 的氘代化合物。 | |||
TMID-0074 |
Fluvoxamine-d4 maleate
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Fluvoxamine-d4 maleate 是 Fluvoxamine maleate 的氘代化合物。Fluvoxamine maleate 的 CAS 号为 61718-82-9。Fluvoxamine maleate 是一种5-羟色胺再吸收抑制剂,有抗抑郁作用。 | |||
TMIJ-0524 |
Triethanolamine-d15
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Triethanolamine-d15 是 Triethanolamine 的氘代化合物。Triethanolamine 的 CAS 号为 102-71-6。 | |||
TMIH-0483 |
Ractopamine-d6 (Mixture of Diastereomers)
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Ractopamine-d6 (Mixture of Diastereomers) 是 Ractopamine (Mixture of Diastereomers) 的氘代化合物。 | |||
T12447 |
Phenylacetylglutamine-D5
NSC 203800-D5,Phenylacetyl-L-glutamine-D5 |
Others | Others |
Phenylacetylglutamine-D5 is a deuterated form of Phenylacetylglutamine. | |||
T19448 |
N-Desmethyl Clomipramine-d3
Desmethylclomipramine D3 hydrochloride |
Others | Others |
N-Desmethyl Clomipramine-d is the deuterium labeled N-Desmethyl Clomipramine. | |||
TMIH-0047 |
3-Methoxy Dopamine-d4 Hydrochloride
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3-Methoxy Dopamine-d4 Hydrochloride 是 3-Methoxy Dopamine Hydrochloride 的氘代化合物。 | |||
TMIJ-0229 |
Mesalamine-d3
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Mesalamine-d3 是 Mesalamine 的氘代化合物。Mesalamine 的 CAS 号为 89-57-6。5-Aminosalicylic Acid 是一种特异性的PPARγ激动剂,还抑制 p21-激活激酶1 (PAK1) 和NF-κB,具有抗炎活性。 | |||
TMIJ-0350 |
N-Nitroso-Di-n-Butylamine-d18
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N-Nitroso-Di-n-Butylamine-d18 是 N-Nitroso-Di-n-Butylamine 的氘代化合物。N-Nitroso-Di-n-Butylamine 的 CAS 号为 924-16-3。 | |||
TMIJ-0439 |
N-Nitrosodiisobutylamine-d4
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N-Nitrosodiisobutylamine-d4 是 N-Nitrosodiisobutylamine 的氘代化合物。N-Nitrosodiisobutylamine 的 CAS 号为 997-95-5。 | |||
TMID-0174 |
N-Nitrosodiphenylamine-d6
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N-Nitrosodiphenylamine-d6 是 N-Nitrosodiphenylamine 的氘代化合物。N-Nitrosodiphenylamine 的 CAS 号为 86-30-6。 | |||
TMIJ-0402 |
N-Nitrosodiethylamine-d10
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N-Nitrosodiethylamine-d10 是 N-Nitrosodiethylamine 的氘代化合物。N-Nitrosodiethylamine 的 CAS 号为 55-18-5。N-Nitrosodiethylamine 是致癌物质二烷基硝胺。它主要存在于水、烟草烟雾、腌制食品、油炸食品以及许多酒精饮料中。它与DNA修复/复制相关的核酶的变化相关。 | |||
TMID-0153 |
MELATONIN(ACETYL-d3)
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MELATONIN(ACETYL-d3) 是 MELATONIN 的氘代化合物。MELATONIN 的 CAS 号为 73-31-4。Melatonin 是一种由松果体制成的激素,可激活褪黑激素受体。它在睡眠中起作用,有抗氧化和抗炎特性。它是新型选择性ATF-6抑制剂,可诱导细胞凋亡。 |