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Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity.
Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥ 17,200 | 10-14周 | |
50 mg | ¥ 22,800 | 10-14周 | |
100 mg | ¥ 29,500 | 10-14周 |
产品描述 | Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity. |
体外活性 | Squalamine lactate has a more general effect on the cell signaling cascade, which is common to VEGF and other growth factors[1]. Squalamine blocks the action of VEGF and integrin expression, thereby inhibiting angiogenesis, when bound to calmodulin[2]. |
体内活性 | When administered intravitreally and therefore requires intravenous dosing, Squalamine is ineffective . However, systemic dosing has yielded promising results in rats as well as humans[2]. |
别名 | MSI-1256F |
分子量 | 718.04 |
分子式 | C37H71N3O8S |
CAS No. | 320725-47-1 |
密度 | no data available |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 36.66 mg/mL (51.06 mM) | ||||||||||||||||||||||||||||||
溶液配制表 | |||||||||||||||||||||||||||||||
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