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265

抑制剂 & 化合物

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240

重组蛋白

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同位素标记化合物

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Cat. No. Product Name
L3200 自噬库

1248 compounds
1248 种细胞自噬相关的生物活性小分子化合物的特有集合,用于自噬相关的研究,用于高通量、高内涵筛选;
L1580 GPCR库Plus

338 compounds
338 种GPCR 靶向、结构新颖的化合物;
L1500 GPCR靶点分子库

1940 compounds
1940 种与 G 蛋白及其耦联受体相关的生物活性小分子化合物,所有小分子都具有良好的生物和药理活性,部分是 FDA 批准的上市药物;
L2150 抗癌药物库

3080 compounds
3080 个具有抗癌活性小分子的独特集合,生物活性已经临床前实验证实,可用于高通量、高内涵筛选;
L2160 抗癌活性化合物库

3188 compounds
3188 种具有抗肿瘤活性的化合物的特有集合,用于高通量、高内涵筛选;
L3600 细胞因子抑制剂库

604 compounds
604 个与细胞因子紧密相关的化合物集合,是高通量、高内涵筛选的良好载体;
L2120 抗癌临床化合物库

2545 compounds
2545 个具有抗癌活性小分子的独特集合,可用于高通量高内涵筛选。
L2110 抗癌上市药物库

1779 compounds
1779 个具有抗癌活性小分子的独特集合,所有化合物都经过了严格的临床前研究和临床试验,由FDA、EMA 或NMPA 批准上市,可用于高通量、高内涵筛选。
L2100 抗癌化合物库

7234 compounds
7234 种肿瘤相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L2180 抗肿瘤库Plus

1468 compounds
1468 种抗肿瘤相关、结构新颖的化合物;
L4010 已知活性化合物库

22555 compounds
22555 个已知活性化合物的集合,可用于高通量筛选、高内涵筛选、细胞诱导和靶点确认;
L4700 免疫/炎症分子化合物库

4720 compounds
4720 种具有抗炎症活性的化合物的特有集合,可用于高通量筛选和高内涵筛选;
L2540 肠道微生物代谢化合物库

614 compounds
614 种肠道微生物代谢物的集合,可以用于高通量和高内涵筛选;
L3800 NF-κB 通路分子库

729 compounds
729 个 NF-κB 信号通路相关的小分子化合物的特有集合,用于高通量、高内涵筛选;
L9420 外泌体相关化合物库

76 compounds
76 种外泌体相关的化合物,可以用于高通量和高内涵筛选;
L2190 抗肺癌化合物库

1702 compounds
1702 种与肺癌相关的化合物,可以用于抗肺癌药物研发和药理研究;
L2170 肿瘤免疫治疗小分子化合物库

449 compounds
449 种靶向肿瘤免疫治疗靶点的小分子,可用于高通量和高内涵筛选,是研究肿瘤免疫治疗的有力工具;

化合物库

自噬库
Cat.No: L3200
Compounds: 1248
GPCR库Plus
Cat.No: L1580
Compounds: 338
GPCR靶点分子库
Cat.No: L1500
Compounds: 1940
抗癌药物库
Cat.No: L2150
Compounds: 3080
抗癌活性化合物库
Cat.No: L2160
Compounds: 3188
细胞因子抑制剂库
Cat.No: L3600
Compounds: 604
抗癌临床化合物库
Cat.No: L2120
Compounds: 2545
抗癌上市药物库
Cat.No: L2110
Compounds: 1779
抗癌化合物库
Cat.No: L2100
Compounds: 7234
抗肿瘤库Plus
Cat.No: L2180
Compounds: 1468
已知活性化合物库
Cat.No: L4010
Compounds: 22555
免疫/炎症分子化合物库
Cat.No: L4700
Compounds: 4720
肠道微生物代谢化合物库
Cat.No: L2540
Compounds: 614
NF-κB 通路分子库
Cat.No: L3800
Compounds: 729
外泌体相关化合物库
Cat.No: L9420
Compounds: 76
抗肺癌化合物库
Cat.No: L2190
Compounds: 1702
肿瘤免疫治疗小分子化合物库
Cat.No: L2170
Compounds: 449
Cat. No. Product Name Target Signaling Pathways
T83705 BING TFA

Blocker of Inter-membrane Stress Responses of Gram-negative Bacteria

BING是一种来源于日本稻田鱼(O. laptipes)的抗菌肽,由液泡蛋白质分选相关蛋白13D样(Vps13D)衍生而来。对包括耐甲氧西林的金黄色葡萄球菌(MRSA; MICs = 4-64 µg/ml)在内的各种革兰氏阴性和革兰氏阳性细菌都有活性。与氨苄西林、阿莫西林和新霉素共同使用时,对抗铜绿假单胞菌(P. aeruginosa)表现出协同效应,并能抑制大肠杆菌(E. coli)对卡那霉素和氨苄西林的抗药性发展。在体内,BING提高了被鳗弧菌(E. tarda)感染的O. laptipes的生存率。
T7954 YM976

PDE Metabolism
YM976 是磷酸二酯酶 4 抑制剂(IC50:2.2 nM)。它能够抑制抗原诱导的气道反应,并有抗炎的作用。
T38361 GSK717

IL Receptor; NOD Immunology/Inflammation; NF-κB
GSK717 是 NOD2(核苷酸结合寡聚结构域 2) 的选择性抑制剂。它抑制壁酰二肽 (MDP) 诱导的 NOD2 介导的信号转导,抑制 MDP 刺激的 HEK293/hNOD2 细胞分泌 IL-8 (IC50为 400 nM)。
T7123 AMG-47a

VEGFR; p38 MAPK; JAK; Src Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; MAPK; Stem Cells; Tyrosine Kinase/Adaptors
AMG-47a 是具有口服活性的 Lck 抑制剂,IC50值为 0.2 nM。它具有抗炎作用,对 VEGF2、p38α、p38α、Jak3、MLR 和 IL-2的 IC50值分别为 1、3、72、30 和 21 nM。
T3189 B7/CD28 interaction inhibitor 1

CTLA-4 inhibitor

Others Others
B7/CD28 interaction inhibitor 1 (CTLA-4 inhibitor) 是B7.1-CD28相互作用抑制剂(IC50:50 nM)。
T7511 Cyclo(his-pro)

NF-κB; Endogenous Metabolite Metabolism; NF-κB
Cyclo(his-pro) 是一种口服具有活力的,结构上与促甲状腺激素释放激素相关的环状二肽。它能够抑制NF-κB 核积累,也能够穿越脑血屏障并影响多种炎症和应激反应。
T9079 Apostatin-1

Apt-1

Others Others
Apostatin-1 (Apt-1) 是一种新型 TRADD 抑制剂。 Apostatin-1 可以与 TRADD 的 N 末端 TRAF2 结合域上的口袋结合。
T3461 Losartan Carboxylic Acid

EXP-3174,E-3174

RAAS Endocrinology/Hormones
Losartan Carboxylic Acid (E-3174) 是 Losartan 的活性羧酸代谢产物,是血管紧张素Ⅱ受体 1 型(AT1)拮抗剂。它能够阻断血管紧张素 II 诱导的血管平滑肌细胞反应,可以提高血浆肾素活性,降低平均动脉压。
T4686 Simeprevir

TMC435,西咪匹韦,TMC-435350,Olysio

HCV Protease; SARS-CoV Microbiology/Virology; Proteases/Proteasome
Simeprevir (TMC435) 是一种有效的 HCV NS3/4A 蛋白酶抑制剂,抑制 HCV 复制,EC50 为 7.8 nM。它也是 SARS-CoV-2 3CLpro 抑制剂。
T21608L β-Interleukin I (163-171), human Acetate

β-Interleukin I (163-171), human Acetate(106021-96-9 Free base)

Others Others
β-Interleukin I (163-171), human Acetate 是一种参与调节免疫反应、炎症反应和造血的肽。
T77761 BMS-502

Others Others
BMS-502 是一种二酰基甘油激酶 (DGK) α 和 ζ 的强效双重抑制剂, 诱导人和小鼠T细胞的免疫反应,阻断 T 细胞中细胞内检查点信号传导。BMS-502 以剂量依赖的方式刺激免疫反应,可用于研究与免疫相关的疾病。
T20571 cis-PDA

哌啶-2,3-二羧酸,cis PDA

GluR; NMDAR; iGluR Membrane transporter/Ion channel; Neuroscience
cis-PDA (cis PDA) 是一种通用的离子型受体拮抗剂。 cis-PDA 通过阻断 NMDA、AMPA 和红藻氨酸介导的反应发挥作用。
T28540 Ripisartan

UP 269-6,UP-2696,UP 2696,UP-269-6,UP269-6

RAAS Endocrinology/Hormones
Ripisartan (UP-269-6) 是一种强效的特异性血管紧张素 II 受体拮抗剂,对血管紧张素 II 介导的交感神经性心动过速反应有抑制作用。
T78082 Supercinnamaldehyde

NF-κB; Antibacterial; TRP/TRPV Channel Membrane transporter/Ion channel; Microbiology/Virology; NF-κB
Supercinnamaldehyde 是一种瞬时受体电位锚蛋白1(TRPA1)激活剂,具有千的抗癌和抗菌活性。Supercinnamaldehyde 抑制NF-κB信号传导,通过Nrf2诱导诱导细胞保护反应和抑制炎症反应。
T11877 LR-90

Others Others
LR-90, 作为一种高级糖基化终产品(AGE)抑制剂,在糖尿病动物模型研究中被广泛使用。LR-90 有效地抑制了人类单核细胞中的炎症反应。
T9292 ALE-0540

ALE0540

Others; Trk receptor Others; Tyrosine Kinase/Adaptors
ALE-0540是一种非肽类杂环分子,可抑制NGF 与p75和TrkA 的结合,以及TrkA 受体介导的信号转导和生物反应。
T11492 GSK2983559 free acid

Others; RIP kinase Apoptosis; NF-κB; Others
GSK2983559 free acid 是一种有效的特异性受体相互作用蛋白 2 (RIP2) 抑制剂。 GSK2983559 free acid 在阻断人类炎症性肠病外植体样品和体内的许多促炎细胞因子反应方面表现出优异的活性。
T12241 Norbinaltorphimine dihydrochloride

nor-BNI dihydrochloride,Nor-BNI dihydrochloride,nor-Binaltorphimine dihydrochloride,Nor-Binaltorphimine dihydrochloride

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
Norbinaltorphimine dihydrochloride是一种具有选择性和有效性的κ阿片受体 (κ opioid receptor) 拮抗剂,可在小鼠中诱导瘙痒相关反应。
T13932 TLR1

N-[(1S)-2-甲基-1-(1-吡咯烷羰基)丙基]-苯丙酰胺

Others; MyD88 Immunology/Inflammation; Others
TLR1 是细胞穿透 Toll/IL-1 receptor/resistance (TIR) domain/BB-Loop 的小分子模拟物,能够阻碍 IL-1 受体介导的反应。
T36716 RO0270608

Integrin Cytoskeletal Signaling
RO0270608,是 R411 的活性代谢物,是一种具有口服活性的双重 α4β1/α4β7 整合素拮抗剂,具有抗炎活性,可调节炎症,可用于研究过敏性炎症反应。
T1076 Dexamethasone

MK 125,Prednisolone F,NSC 34521,Hexadecadrol,地塞米松

Glucocorticoid Receptor; Mitophagy; IL Receptor; SARS-CoV; Antibacterial; Antibiotic; Autophagy; Complement System; ADC Cytotoxin Antibody-drug Conjugate/ADC Related; Autophagy; Endocrinology/Hormones; Immunology/Inflammation; Microbiology/Virology
Dexamethasone (Hexadecadrol) 是一种糖皮质激素受体激动剂和一种 IL 受体调节剂。Dexamethasone 具有抗炎和免疫抑制活性,可诱导自噬。Dexamethasone 抑制 LPS 诱导的巨噬细胞炎症反应。
T35258 YM 16638

YM 638,YM-16638,YM16638

LTR Immunology/Inflammation
YM 16638 是一种具有口服活性的白三烯(LT)拮抗剂,具有降低甘油三酯和增加过氧化物酶体的作用,可用于研究抗原诱导过敏性绵羊早期和晚期气道反应。
T78181 MMP-7-IN-2

MMP; Others Others; Proteases/Proteasome
MMP-7-IN-2 可作为一种具有选择性和有效性的 MMP7 抑制剂,可用于研究炎症反应和与血管相关的疾病。
T2069L TH287 hydrochloride

DNA/RNA Synthesis; MTH1 Cell Cycle/Checkpoint; DNA Damage/DNA Repair
TH287 hydrochloride 是一种选择性MTH1抑制剂,IC50值为 0.8 nM。它可用于治疗癌症的研究。
T11630 IFN alpha-IFNAR-IN-1 hydrochloride

Others; IFNAR Immunology/Inflammation; Others
IFN alpha-IFNAR-IN-1 hydrochloride 是 IFN-α 和 IFNAR 相互作用的抑制剂。 IFN alpha-IFNAR-IN-1 hydrochloride 抑制 BM-pDCs 的 MVA 诱导的 IFN-α 反应,IC50 为 2-8 μM。
T9119 SU0268

Others Others
SU0268 是有效的 8-8-氧鸟嘌呤 DNA 糖基化酶1的选择性抑制剂,具有调控铜绿假单胞杆菌感染免疫反应的能力。
T19051 Reactive Blue 4

活性艳蓝X-ARL,活性蓝4

Others Others
Reactive Blue 4 是蒽醌类染料,具有植物毒性、细胞毒性和基因毒性。它可作为单一的比色化学传感器,用于在水介质中连续测定具有不同光学响应的多种分析物。
T14377 AZD5423

Glucocorticoid Receptor Endocrinology/Hormones
AZD5423 是可吸入的非甾体糖皮质激素受体选择性调节剂,能够有效降改善轻度过敏性哮喘患者的过敏原诱导反应。
T22414 RBN012759

PARP Chromatin/Epigenetic; DNA Damage/DNA Repair
RBN012759 是选择性和具有口服活性的 PARP14抑制剂,IC50值小于3 nM,可降低促肿瘤巨噬细胞功能并在肿瘤外植体中引发炎症反应,比对 monoPARPs 的选择性高 300 倍,比对 polyPARPs 的选择性高 1000 倍。
T4613 Arg-Gly-Asp TFA (99896-85-2(free base))

RGD Trifluoroacetate,RGD

Integrin Cytoskeletal Signaling
Arg-Gly-Asp TFA (99896-85-2(free base)) (RGD Trifluoroacetate) 是一种三肽,可有效触发细胞粘附、定位某些细胞系并引发特定的细胞反应;与整合素结合。
T2401 Alogliptin Benzoate

苯甲酸阿格列汀,SYR 322,Alogliptin(SYR-322)benzoate

Ferroptosis; Proteasome; DPP-4 Apoptosis; Proteases/Proteasome; Ubiquitination
Alogliptin Benzoate (SYR 322) 是一种有效且特异性的 DPP-4 抑制剂 ,IC50值小于 10 nM,其选择性比 DPP-8/9 高 10,000 倍以上,可用于研究 2 型糖尿病。
T5489 Tryptophan, N-indol-3-ylacetyl- (6CI)

N-(3-吲哚乙酰基)-L-色氨酸,N-(3-Indolylacetyl)-L-tryptophan,Indole-3-acetyl-L-tryptophan

Glucosidase Metabolism
Tryptophan, N-indol-3-ylacetyl- (6CI) (Indole-3-acetyl-L-tryptophan) 参与调节生理和病理生理反应过程中生长素活性的调节机制。还可用于合成β-D-半乳糖苷酶和β-D-葡萄糖苷酶抑制剂。
T14513 BBIQ

TLR Immunology/Inflammation
BBIQ 是一种有效且选择性的 toll 样受体 7 (TLR7) 激动剂,对人 TLR7 的 EC50 为 59.1 nM。BBIQ 还是一种功能强大的疫苗佐剂,可增强机体的先天免疫应答。
T3977L Lifitegrast sodium

SAR-1118-023,SAR1118-023,SAR 1118-023,Xiidra

Others Others
Lifitegrast sodium (SAR-1118) is an LFA-1 antagonist for the therapy of vascular complications of the eye. It inhibits T cell-mediated inflammation by blocking the binding of two cell surface proteins (lymphocyte function-associated antigen 1 and intercel
T19930 Nitrosoglutathione

S-Nitrosoglutathione,S-亚硝基谷胱甘肽,SNOG,Glutathione thionitrite,GSNO

RAAS; NO Synthase Endocrinology/Hormones; Immunology/Inflammation
Nitrosoglutathione (GSNO) 是一种外源性的 NO 供体,是大鼠酒精脱氢酶III 类同工酶的底物,能够减少脑血管紧张素II 依赖性及非依赖型的 AT1 受体反应。
TP2209L Xenin 8 acetate

Xenin 8 acetate (117442-28-1 Free base)

IGF-1R Tyrosine Kinase/Adaptors
Xenin 8 acetate 是神经降压素/异视素家族中 Xenin 的生物活性片段。 Xenin 8 acetate 增强精氨酸诱导的胰岛素释放(40%)并增强胰高血糖素对精氨酸(60%)和卡巴胆碱(50%)的反应。
T10432L AZD-8529 mesylate

GluR Neuroscience
AZD-8529 mesylate 是高度选择性的可口服mGluR2正向调节剂,EC50值为 285 nM。它在 20-25 M 时,对 mGluR1、3、4、5、6、7 和 8 亚型没有显示正变构调节剂反应。
T76699 Sabatolimab

MBG453,NVP-MBG453

Others Others
Sabatolimab (MBG453) 是一种靶向 TIM-3的人源化 IgG4 (S228P) 抗体,是一种有效的调节适应性和先天免疫反应的抑制性受体。Sabatolimab 具有潜在的免疫抑制活性,可选择性与免疫细胞和骨髓细胞上的 TIM-3 结合。
T31615 Elsibucol

AGI-1096,UNII-O7T92N1Y8T,AGI 1096

Antioxidant oxidation-reduction
Elsibucol (AGI 1096) 是一种VCAM1抑制剂,可用于研究器官移植排斥。Elsibucol 是一种代谢稳定的丙醇衍生物,具有抗氧化、抗炎和抗增殖的特性。它能降低血液中的胆固醇水平,减少受伤动脉中的氧化应激和炎症反应,从而抑制动脉粥样硬化,保护动脉损伤后的内皮愈合。
T19723 AMTB hydrochloride

AMTB

TRP/TRPV Channel Membrane transporter/Ion channel
AMTB hydrochloride (AMTB HCl) 是TRPM8通道的选择性阻滞剂。它抑制 icilin 诱导的 TRPM8 通道激活,pIC50为 6.23。它在膀胱过度活动和膀胱疼痛综合征中有研究的价值。它是电压门控钠通道的非选择性抑制剂 (NaV)。
T31195 Dalcotidine

KU 1257,KU-1257

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Dalcotidine (KU 1257) 是一种新型组胺H2受体拮抗剂,具有组胺H9受体拮抗活性和抗分泌作用,与豚鼠大脑皮层结合的Ki 值为0.040 对分离性豚鼠右心房组胺诱导的正变时反应的拮抗作用的KB 值为0.041。Dalcotidine 提高了溃疡愈合的质量,可能有助于降低溃疡的复发率和复发率。
T13867 RH01386

Others Others
RH01386是可以预防 ER 应激诱导的β细胞功能障碍和死亡、抑制促凋亡基因表达的小分子。它恢复内质网应激受损的葡萄糖刺激的胰岛素分泌反应。对2型糖尿病具有潜在的研究价值。
T11800 L-803087

Somatostatin GPCR/G Protein
L-803087 是一种具有高效性和选择性的生长抑素 sst4 受体激动剂,对 sst4 的 Ki 值为 0.7 nM,比其他生长抑素受体的选择性高 280 倍以上。L-803087 在体外诱导 AMPA 介导的海马突触反应,在体内增加了海藻酸盐促使的小鼠癫痫发作。
T3614 Inosine pranobex

Groprinosin,Isoprinosine,异丙肌苷,Immunovir,Delimmun

IL Receptor; HIV Protease Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
Inosine pranobex (Delimmun) 是一种免疫增强剂,它是一种广谱抗病毒剂,用于 HIV 感染。
T16478 PF-04447943

PF 04447943,Edelinontrine,PF04447943

PDE Metabolism
PF-04447943 (Edelinontrine) 是一种有效且具有选择性的的磷酸二酯酶 9A 抑制剂,IC50 为 12 nM,比作用于其他PDE家族成员选择性高 78 倍 (IC50>1000 nM)。PF-04447943 具有抗炎活性,通过抑制氧化应激、炎症和调节T细胞极化来减轻炎症反应,且可用于研究镰刀型贫血症。
T0943 Carbamazepine

卡马西平,NSC 169864

Mitophagy; Sodium Channel; Autophagy Autophagy; Membrane transporter/Ion channel
Carbamazepine (NSC-169864) 是与三环抗抑郁药化学相关的三环化合物,具有抗惊厥和镇痛特性。它通过减少多突触反应和阻断强直后增强发挥其抗惊厥活性。 它通常用于治疗与三叉神经痛相关的疼痛。
T9897 7-Methoxy-1-naphthaleneacetic acid

Others Others
7-Methoxy-1-naphthaleneacetic acid 是植物生长素作用的抑制剂。 7-Methoxy-1-naphthaleneacetic acid 抑制与拟南芥和玉米中生长素不对称分布相关的极性生长素转运和热带反应。 7-Methoxy-1-naphthaleneacetic acid 抑制由酵母中表达的 AUX1、PIN 和 ABCB 蛋白介导的生长素转运。
T1435 Praziquantel

吡喹酮,Pyquiton,Droncit,Biltricide

Calcium Channel; Antibiotic; Parasite Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
Praziquantel (Droncit) 是一种外消旋混合物,由 (R)-Praziquantel 和 (S)-Praziquantel 组成。它可研究血吸虫病。
T4206 E6446

TLR Immunology/Inflammation
E6446 抑制 Toll 样受体 (TLR)7 和 9 信号传导。 E6446 在多种人和小鼠细胞类型中起作用,并在体外抑制 DNA-TLR9 相互作用。当给予小鼠时,该化合物抑制对刺激 TLR9 的含有胞苷-磷酸-胍 (CpG) 的 DNA 的挑战剂量的反应。
T50068 (2S,5S)-3,6-Dioxo-2,5-piperazinediacetamide

Others Others
2-[(2S,5S)-5-(carbamoylmethyl)-3,6-dioxopiperazin-2-yl]acetamide 是一种用作分子结构单元的化合物,为环状二肽。它可以诱导细胞凋亡、抑制细胞增殖和调节免疫反应,具有广泛的生物活性,包括抗肿瘤、抗真菌、抗细菌、抗病毒和免疫条件活性等。

化合物

BING TFA
Cat.No: T83705
Synonym: Blocker of Inter-membrane Stress Responses of Gram-negative Bacteria
Target:
YM976
Cat.No: T7954
Synonym:
Target: PDE
GSK717
Cat.No: T38361
Synonym:
Target: IL Receptor, NOD
AMG-47a
Cat.No: T7123
Synonym:
Target: VEGFR, p38 MAPK, JAK, Src
B7/CD28 interaction inhibitor 1
Cat.No: T3189
Synonym: CTLA-4 inhibitor
Target: Others
Cyclo(his-pro)
Cat.No: T7511
Synonym:
Target: NF-κB, Endogenous Metabolite
Apostatin-1
Cat.No: T9079
Synonym: Apt-1
Target: Others
Losartan Carboxylic Acid
Cat.No: T3461
Synonym: EXP-3174,E-3174
Target: RAAS
Simeprevir
Cat.No: T4686
Synonym: TMC435,西咪匹韦,TMC-435350,Olysio
Target: HCV Protease, SARS-CoV
β-Interleukin I (163-171), human Acetate
Cat.No: T21608L
Synonym: β-Interleukin I (163-171), human Acetate(106021-96-9 Free base)
Target: Others
BMS-502
Cat.No: T77761
Synonym:
Target: Others
cis-PDA
Cat.No: T20571
Synonym: 哌啶-2,3-二羧酸,cis PDA
Target: GluR, NMDAR, iGluR
Ripisartan
Cat.No: T28540
Synonym: UP 269-6,UP-2696,UP 2696,UP-269-6,UP269-6
Target: RAAS
Supercinnamaldehyde
Cat.No: T78082
Synonym:
Target: NF-κB, Antibacterial, TRP/TRPV Channel
LR-90
Cat.No: T11877
Synonym:
Target: Others
ALE-0540
Cat.No: T9292
Synonym: ALE0540
Target: Others, Trk receptor
GSK2983559 free acid
Cat.No: T11492
Synonym:
Target: Others, RIP kinase
Norbinaltorphimine dihydrochloride
Cat.No: T12241
Synonym: nor-BNI dihydrochloride,Nor-BNI dihydrochloride,nor-Binaltorphimine dihydrochloride,Nor-Binaltorphimine dihydrochloride
Target: Opioid Receptor
TLR1
Cat.No: T13932
Synonym: N-[(1S)-2-甲基-1-(1-吡咯烷羰基)丙基]-苯丙酰胺
Target: Others, MyD88
RO0270608
Cat.No: T36716
Synonym:
Target: Integrin
Dexamethasone
Cat.No: T1076
Synonym: MK 125,Prednisolone F,NSC 34521,Hexadecadrol,地塞米松
Target: Glucocorticoid Receptor, Mitophagy, IL Receptor, SARS-CoV, Antibacterial, Antibiotic, Autophagy, Complement System, ADC Cytotoxin
YM 16638
Cat.No: T35258
Synonym: YM 638,YM-16638,YM16638
Target: LTR
MMP-7-IN-2
Cat.No: T78181
Synonym:
Target: MMP, Others
TH287 hydrochloride
Cat.No: T2069L
Synonym:
Target: DNA/RNA Synthesis, MTH1
IFN alpha-IFNAR-IN-1 hydrochloride
Cat.No: T11630
Synonym:
Target: Others, IFNAR
SU0268
Cat.No: T9119
Synonym:
Target: Others
Reactive Blue 4
Cat.No: T19051
Synonym: 活性艳蓝X-ARL,活性蓝4
Target: Others
AZD5423
Cat.No: T14377
Synonym:
Target: Glucocorticoid Receptor
RBN012759
Cat.No: T22414
Synonym:
Target: PARP
Arg-Gly-Asp TFA (99896-85-2(free base))
Cat.No: T4613
Synonym: RGD Trifluoroacetate,RGD
Target: Integrin
Alogliptin Benzoate
Cat.No: T2401
Synonym: 苯甲酸阿格列汀,SYR 322,Alogliptin(SYR-322)benzoate
Target: Ferroptosis, Proteasome, DPP-4
Tryptophan, N-indol-3-ylacetyl- (6CI)
Cat.No: T5489
Synonym: N-(3-吲哚乙酰基)-L-色氨酸,N-(3-Indolylacetyl)-L-tryptophan,Indole-3-acetyl-L-tryptophan
Target: Glucosidase
BBIQ
Cat.No: T14513
Synonym:
Target: TLR
Lifitegrast sodium
Cat.No: T3977L
Synonym: SAR-1118-023,SAR1118-023,SAR 1118-023,Xiidra
Target: Others
Nitrosoglutathione
Cat.No: T19930
Synonym: S-Nitrosoglutathione,S-亚硝基谷胱甘肽,SNOG,Glutathione thionitrite,GSNO
Target: RAAS, NO Synthase
Xenin 8 acetate
Cat.No: TP2209L
Synonym: Xenin 8 acetate (117442-28-1 Free base)
Target: IGF-1R
AZD-8529 mesylate
Cat.No: T10432L
Synonym:
Target: GluR
Sabatolimab
Cat.No: T76699
Synonym: MBG453,NVP-MBG453
Target: Others
Elsibucol
Cat.No: T31615
Synonym: AGI-1096,UNII-O7T92N1Y8T,AGI 1096
Target: Antioxidant
AMTB hydrochloride
Cat.No: T19723
Synonym: AMTB
Target: TRP/TRPV Channel
Dalcotidine
Cat.No: T31195
Synonym: KU 1257,KU-1257
Target: Histamine Receptor
RH01386
Cat.No: T13867
Synonym:
Target: Others
L-803087
Cat.No: T11800
Synonym:
Target: Somatostatin
Inosine pranobex
Cat.No: T3614
Synonym: Groprinosin,Isoprinosine,异丙肌苷,Immunovir,Delimmun
Target: IL Receptor, HIV Protease
PF-04447943
Cat.No: T16478
Synonym: PF 04447943,Edelinontrine,PF04447943
Target: PDE
Carbamazepine
Cat.No: T0943
Synonym: 卡马西平,NSC 169864
Target: Mitophagy, Sodium Channel, Autophagy
7-Methoxy-1-naphthaleneacetic acid
Cat.No: T9897
Synonym:
Target: Others
Praziquantel
Cat.No: T1435
Synonym: 吡喹酮,Pyquiton,Droncit,Biltricide
Target: Calcium Channel, Antibiotic, Parasite
E6446
Cat.No: T4206
Synonym:
Target: TLR
(2S,5S)-3,6-Dioxo-2,5-piperazinediacetamide
Cat.No: T50068
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T5826 Eupalinolide A

HSP Cytoskeletal Signaling; Metabolism
Eupalinolide A 是分离于林泽兰中的一种天然产物,通过抑制 HSF1 与 HSP90 的相互作用,激活 HSF1,诱导 HSP70 的表达。它对 A-549、BGC-823、SMMC-7721 和 HL-60 肿瘤细胞系具有强大的细胞毒性。
T13502 3-Oxo-5β-cholanoic acid

3-氧代-5β-胆烷酸,Dehydrolithocholic acid

ROR Metabolism
3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid) 是胆汁酸的一种代谢产物。3-Oxo-5β-cholanoic acid 直接与关键转录因子RORγt(Kd=1.13 μM) 结合抑制TH17细胞分化。
TN2088 Platycodin D2

桔梗皂苷D2

IL Receptor; HBV Immunology/Inflammation; Microbiology/Virology
Platycodin D2 是分离自桔梗的皂苷类物质,显示除抗癌活性。
T3319 Scutellarein

野黄芩素,4',5,6,7-Tetrahydroxyflavone,6-Hydroxyapigenin

SARS-CoV; Src; Autophagy Angiogenesis; Autophagy; Microbiology/Virology; Tyrosine Kinase/Adaptors
Scutellarein (6-Hydroxyapigenin) 是一种天然黄酮,具有抗炎功效。
T0948L Corticosterone

皮质酮,17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,肾上腺酮,Corticosterone (From plants)

Glucocorticoid Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism
Corticosterone (Kendall's compound B) 是一种肾上腺皮质类固醇,有盐皮质激素和糖皮质激素的活性,具有口服活性。Corticosterone 参与体内能量、免疫反应和应激反应的调节。
T13557 Ascr#5

Ascaroside C3

Others Others
Ascr#5 (asc-ωC3)是秀丽隐杆线虫中高度保守的蛔苷类物质,可调节秀丽隐杆线虫的多种反应。
T5235 5-Methoxy-DL-tryptophan

Others; Endogenous Metabolite Metabolism; Others
5-Methoxy-DL-tryptophan 是内源性代谢产物的一种。
TN2349 Taurodeoxycholate sodium salt

Sodium taurodeoxylate,牛磺脱氧胆酸钠

Endogenous Metabolite Metabolism
Taurodeoxycholate sodium salt (Sodium taurodeoxylate) 是胆盐相关的阴离子洗涤剂,用于分离膜蛋白,包括线粒体内膜蛋白。它还可以抑制各种炎症反应。
TN1052 Lindleyin

Estrogen Receptor/ERR; Estrogen/progestogen Receptor Endocrinology/Hormones
Lindleyin 是从 Rhei rhizoma 中分离得到,通过雌激素受体介导激素作用。它能够与 ERα结合,有类似雌激素的作用。
TN1594 DL-Syringaresinol

(±)-Syringaresinol

Antioxidant; Antifungal Microbiology/Virology; oxidation-reduction
DL-Syringaresinol ( (±)-Syringaresinol) 是一种来自与人参浆果的木质素,具有抗炎、抗氧化、镇痛活性和较弱的抗分枝杆菌活性。DL-Syringaresinol 可通过自噬延缓氧化应激诱导的皮肤老化,通过抑制炎症反应来缓解奥沙利铂诱导的神经性疼痛和脓毒症引起的心功能障碍。
TN6457 N-trans-caffeoyltyramine

Trans-N-Caffeoyltyramine,N-(E)-Caffeoyl-lambda-tyramine,N-cis-Caffeoyltyramine,Typheramide

Immunology/Inflammation related Immunology/Inflammation
N-trans-caffeoyltyramine (Trans-N-Caffeoyltyramine) 是炎症反应的调节剂,可用于慢性炎症性疾病治疗的研究。
T13555 Ascr#2

Ascaroside C6

Others Others
Ascr#2 (asc-C6-MK)是秀丽隐杆线虫中的糖苷类化合物,促进 dauer 形成。Ascr#2 在低浓度下与 ascr#3 的混合物可作为雄性引诱剂,可用于检测种群密度。
T67710 3-Indoleacrylic acid

Endogenous Metabolite Metabolism
3-Indoleacrylic acid 是由链球菌属产生的色氨酸的代谢产物。3-Indoleacrylic acid 对肠上皮屏障功能有有益作用,并减轻免疫细胞的炎症反应。
T5731 1-Kestose

蔗果三糖,1-蔗果三糖

Others; Endogenous Metabolite; Antibacterial Metabolism; Microbiology/Virology; Others
1-Kestose 是低聚果糖成分,有效刺激了 Faecalibacterium prausnitzii 和 Bifidobacteria。它有抗羟基自由基的潜力。它可促进肠道内乳酸菌数量,影响微生物以及肠道和全身免疫反应。
T2842 Tangeretin

NSC53909,Tangeritin,NSC618905,桔皮素

Apoptosis; Gamma-secretase Apoptosis; Neuroscience; Proteases/Proteasome; Stem Cells
Tangeretin (NSC-618905) 是一种来自柑橘类水果果皮的类黄酮,是一种Notch-1抑制剂,具有抗炎,保护神经等作用。
TN1879 Lucideric acid A

Lucidenic acid A,赤芝酸A

MMP; p38 MAPK; JNK MAPK; Proteases/Proteasome
Lucideric acid A (Lucidenic acid A) 是分离自灵芝的天然产物,可抑制 PMA 诱导的MMP-9活性,具有抵抗肝癌细胞侵袭的作用。
T6S0657 Isorhynchophylline

IsoRhy,异钩藤碱,Isorhyncophylline,Isorhychophylline,7-Isorhyncophylline

Others Others
Isorhynchophylline (7-Isorhyncophylline) 是一种分离自钩藤中的生物碱类化合物,具有舒张血管、降血压、保护神经免于局部缺血造成损伤的作用。
T5S0089 Kaempferol-3-O-glucorhamnoside

Kaempferol 3-glucorhamnoside,百蕊草素I

Antioxidant; p38 MAPK; NF-κB MAPK; NF-κB; oxidation-reduction
Kaempferol-3-O-glucorhamnoside (Kaempferol 3-glucorhamnoside) 是来源于百蕊草的一种类黄酮,在体内外均能通过 MAPK 和 NF-κB 通路抑制炎症反应。
T4939 Indole-3-pyruvic acid

3-(3-吲哚基)-2-氧代丙酸,3-(3-Indolyl)-2-oxopropanoic acid

Others Others
Indole-3-pyruvic acid (3-(3-Indolyl)-2-oxopropanoic acid) 是一种参与Indole-3-acetic acid 生物合成的化合物,Indole-3-acetic acid 是一种植物激素,在调节生长和对环境变化的反应中起重要作用。
T1614 Hydrocortisone

氢化可的松,Cortisol

Glucocorticoid Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism
Hydrocortisone (Cortisol) 是一种糖皮质激素,由肾上腺素皮质分泌。Hydrocortisone 激动糖皮质激素受体,可促进蛋白质分解代谢、糖异生、毛细血管壁稳定性、肾脏钙排泄,并抑制免疫和炎症反应。
TN1134 Euscaphic acid

Apoptosis; LDL; PI3K; DNA/RNA Synthesis; NO Synthase; Prostaglandin Receptor Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; Metabolism; PI3K/Akt/mTOR signaling
Euscaphic acid 是来源于枣的一种三萜,是DNA 聚合酶抑制剂,可诱导细胞凋亡。它抑制小牛 DNA 聚合酶 α 和大鼠 DNA 聚合酶 β 的IC50值分别为 61 和 108 μM。
T5S0993 Kurarinone

苦参酮,苦参黄素

BCL; Others; IκB/IKK; TNF; NF-κB; JAK; STAT Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; NF-κB; Others; Stem Cells
Kurarinone 是从灌木苦参中提取的黄酮类化合物,具有抗肿瘤、雌激素和抗炎活性,对免疫反应也有很强的抑制作用。
T1004 6-Benzylaminopurine

6-苄氨基嘌呤,6-BAP,N6-Benzyladenine,BA,Benzyladenine

Others Others
6-Benzylaminopurine (6-BAP) 是一种细胞分裂素,能够通过刺激细胞分裂引起植物生长和发育,抑制呼吸激酶,从而延长绿色蔬菜的保鲜。
TN6774 Emodin 6-O-β-D-glucoside

大黄素-6-O-β-D-葡萄糖苷,Glucoemodin

Others Others
Emodin 6-O-β-D-glucoside (Glucoemodin) 是一种从 Reynoutria japonica 中提取的活性化合物。它具有显著的抗炎和屏障保护活性,可用于研究动脉粥样硬化及糖尿病并发症。
T5S1895 Norisoboldine

Laurelliptine,去甲异波尔定,(+)-Laurelliptine

MAPK; Adenosine Receptor GPCR/G Protein; MAPK; Neuroscience
Norisoboldine ((+)-Laurelliptine) 是一种可口服的芳基烃受体激动剂,是乌药中主要的异喹啉类生物碱,可用于类风湿性关节炎和溃疡性结肠炎的研究。
T4928 L-Kynurenine

L-犬尿氨酸,(S)-Kynurenine

AhR; Aryl Hydrocarbon Receptor; Endogenous Metabolite Immunology/Inflammation; Metabolism
L-Kynurenine ((S)-Kynurenine) 是L-色氨酸的代谢物,是芳香烃受体激动剂,可抑制同种异体 T 细胞增殖并增加恶性 U87 神经胶质瘤细胞侵入胶原基质。
T5S1177 Aloin B

Isobarbaloin,芦荟苷B,芦荟素B

Others Others
Aloin B (Isobarbaloin) 是一种芦荟素的异构体。其中芦荟素是芦荟中的具生理活性蒽醌化合物。
T1611 Isotretinoin

13-cis-Retinoic acid,异维A酸

Retinoid Receptor; Endogenous Metabolite; Autophagy Autophagy; Metabolism
Isotretinoin (13-cis-Retinoic acid) 是一种天然存在的维甲酸,具有潜在的抗肿瘤活性。 它结合并激活核视黄酸受体 (RAR), 活化的 RARs 作为促进细胞分化和凋亡的转录因子。它是一种类维生素A 和维生素A 衍生物,用于治疗严重的痤疮和某些形式的皮肤、头颈癌。
T5S1286 (+)-Columbianetin

二氢山芹醇,(S)-Columbianetin,Columbianetin

Antifungal Microbiology/Virology
(+)-Columbianetin ((S)-Columbianetin) 是 Columbianetin 的异构体。其中Columbianetin 是一种植物抗毒素,与芹菜贮藏过程中对病原体的抗性有关,具有良好的抗真菌和抗炎作用。
T3386 Kaempferitrin

Lespedin,Kaempferol,Lespenephryl,Lespenefril,Kaempferol 3,7-dirhamnoside,山奈苷

cell cycle arrest; Glucokinase; IGF-1R Cell Cycle/Checkpoint; Metabolism; Tyrosine Kinase/Adaptors
Kaempferitrin (Lespenephryl) 是天然黄酮苷类化合物,具有缓解疼痛、抗糖尿病、消炎、抗肿瘤和化疗作用,可激活胰岛素信号传导。
T3S0364 L-Arginine

L-精氨酸,L-Arg,(S)-(+)-Arginine

IL Receptor; Endogenous Metabolite; NO Synthase Immunology/Inflammation; Metabolism
L-Arginine (L-Arg) 是内皮型一氧化氮合酶(eNOS) 的底物。L-Arginine 通过阳离子氨基酸转运体家族转运到血管平滑肌细胞,并被代谢成一氧化氮、多胺或 L-脯氨酸。
T3877 Esculentoside A

NF-κB; COX Immunology/Inflammation; Neuroscience; NF-κB
Esculentoside A 是一种三萜皂苷,从商陆根部分离得到。它在具有抗炎活性,对环氧合酶-2 具有选择性抑制活性。它通过抑制NF-κB 和丝裂原活化蛋白激酶信号通路抑制 LPS 诱导的急性肺损伤中的炎症反应。
T4868 gamma-Linolenic acid

gamolenic acid,γ-Linolenic acid,γ-亚麻酸

Endogenous Metabolite Metabolism
gamma-Linolenic acid (gamolenic acid) 是一种 omega-6 (n-6),18 碳 (18C-) 多不饱和脂肪酸 (PUFA),可以从人乳和植物种子油中提取。
T11855 Lipopolysaccharides

脂多糖,LPS

Others Others
Lipopolysaccharides (LPS) 是革兰氏阴性细菌细胞壁的一种特有成分,由脂质A、寡糖核心和 O -特异性多糖 (O-antigen) 3个区域组成。Lipopolysaccharides 有利于维持细胞外膜的完整性,保护细菌免受胆汁盐和脂类抗生素的破坏。Lipopolysaccharides 是一种高免疫原性抗原,可以增强免疫反应,可以用于炎症模型构建。
T3S0737 Flavokawain A

2'-羟基-4,4',6'-三甲氧基查耳酮,Flavokavain A

Apoptosis; p38 MAPK Apoptosis; MAPK
Flavokawain A (Flavokavain A) 是 kava 提取物中的查耳酮,是一种抗癌试剂,具有抗肿瘤活性。它通过 Bax 蛋白依赖和线粒体依赖的凋亡途径诱导细胞凋亡,有潜力用于膀胱癌的相关研究。
T3673 Mollugin

大叶茜草素,Rubimaillin

HER; JAK Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
Mollugin (Rubimaillin) 是Rubia cordifolia L.中主要的生物活性成分。它能通过 p38-Smad 信号通路增强 BMP-2 的成骨作用。它通过抑制 TNF-α 诱导的 NF-κB 激活起抗癌疗效。
T4S2126 Ginkgetin

银杏双黄酮,银杏素

Apoptosis; Wnt/beta-catenin; COX; STAT; Autophagy Apoptosis; Autophagy; Cytoskeletal Signaling; Immunology/Inflammation; JAK/STAT signaling; Neuroscience; Stem Cells
Ginkgetin 是从银杏叶中分离得到的一种双黄酮,具有抗肿瘤、抗炎、神经保护、抗真菌的作用。它也是 Wnt 信号抑制剂,IC50值为 5.92 μM。
T41078 Lipopolysaccharides, Escherichiacoli

Lipopolysaccharide, E. coli O111:B4

Others Others
Lipopolysaccharides, Escherichiacoli (E. coli O111:B4) 是革兰氏阴性细菌细胞壁的一种特有成分,由脂质A、寡糖核心和 O -特异性多糖 (O-antigen) 3个区域组成。Lipopolysaccharides, Escherichiacoli 有利于维持细胞外膜的完整性,保护细菌免受胆汁盐和脂类抗生素的破坏。Lipopolysaccharides, Escherichiacoli 是一种高免疫原性抗原,可以增强免疫反应,可以用于炎症模型构建。
T4S2326 Cornuside

7-Galloylsecologanol,7-O-Galloylsecologanol,山茱萸新苷,Comuside

ERK; p38 MAPK; NF-κB; JNK MAPK; NF-κB
Cornuside (Comuside) 是从山茱萸的果实中分离出的环烯醚萜苷,可用于炎症疾病的研究和促进血液循环。 它通过下调 MAPK 和 NF-κB 信号通路抑制肥大细胞介导的过敏反应,用于炎性过敏性疾病中的潜能。
T35749 Thymohydroquinone

Thymoquinol

Antioxidant; Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
Thymohydroquinone (Thymoquinol) 是中药材百里香、牛至和其他唇形科植物中含有的单萜酚类化合物。 Thymohydroquinone 抑制癌细胞生长、减少氧化应激和调节炎症反应,在无细胞实验中清除2,2-二苯基-1-picrylhydrazyl 自由基(IC50 = 2.4 μg/ml),在浓度为1.6至6.4 μg/ml 的氧自由基吸收能力(ORAC)实验中,它的Trolox 当量值为2.6胸腺对苯二酚对A2780、OVCAR-8和CIS-A2780卵巢癌细胞(IC50分别为3.1、8.9和9.8 μM)和人卵巢永生化上皮细胞(IC50 = 14 μM)的生长有抑制作用,体外对恶性疟原虫也有抑制作用(IC50 = 15.9 μM)。
TN4804 Platycoside A

Antifection Microbiology/Virology
Platycoside A has hemolytic activity and adjuvant potential on the immune responses to Newcastle disease virus-based recombinant avian influenza vaccine. It induces the IgG and IgG1 antibody responses in the immunized mice.
T20217 Grandiflorenic acid

Others Others
Grandiflorenic acid can reproduce the uterine responses induced by aqueous extract of zoapatle leaves. It is suggested that grandiflorenic acid may have an antifertility effect.
TN4882 Quinine HCl

奎宁树

Adrenergic Receptor GPCR/G Protein; Neuroscience
Quinine HCl produces alpha-adrenergic blockade. Quinine modifies catecholamine- and calcium-induced myocardial contractile force responses.
T39179 β-Tomatine

Others Others
β-Tomatine, a derivative of α-tomatine, is a fungitoxic compound that efficiently inhibits plant defense responses.
TN3482 Bakkenolide B

NOS; COX Immunology/Inflammation; Neuroscience
Bakkenolide B has suppressive properties for allergic and inflammatory responses and may be utilized as a potent agent for the treatment of asthma.
T13968 Xanthoplanine

Others Others
Xanthoplanine is a natural product isolated from theroot of Xylopia parviflora, and inhibits the EC50 ACh responses of both alpha7 and alpha4beta2 nACh receptors (IC50 of 9 μM and 5 μMc for alpha7 and alpha4beta2,respectively).
TN4420 Latifolin

檀木

IL Receptor; IκB/IKK; TNF; NOS; NF-κB; COX; Nrf2; Prostaglandin Receptor; Antifection; Autophagy Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience; NF-κB
Latifolin is a strong DPPH-scavenger, it attenuates inflammatory responses by inhibiting NF-κB activation via Nrf2-mediated heme oxygenase-1 expression. Latifolin displays potent anticarcinogenic phase II marker enzyme, quinone reductase (QR) inducing activity and high chemopreventive indices. Latifolin also shows antifungal activity against white- and brown-rot fungi.
T83600 (+)-Dihydrocarvone

(+)-Dihydrocarvone对A. mellifera的触角产生显著反应,并影响其对番茄的觅食行为偏好。
TN7276 Methyl 7(Z)-hexadecenoate

Methyl cis-7-hexadecenoate

Others Others
Methyl 7(Z)-hexadecenoate 是Trogoderma glabrum 生产的一种性信息素,能够吸引并引发雄性Trogoderma glabrum 的性兴奋反应。
T61171 Cyclo(his-pro) TFA

Others Others
Cyclo(his-pro) TFA, an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone, has shown inhibitory effects on NF-κB nuclear accumulation. Additionally, it possesses the ability to cross the blood-brain barrier and impact various inflammatory and stress responses [1, 2].
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天然产物

Eupalinolide A
Cat.No: T5826
Synonym:
Target: HSP
3-Oxo-5β-cholanoic acid
Cat.No: T13502
Synonym: 3-氧代-5β-胆烷酸,Dehydrolithocholic acid
Target: ROR
Platycodin D2
Cat.No: TN2088
Synonym: 桔梗皂苷D2
Target: IL Receptor, HBV
Scutellarein
Cat.No: T3319
Synonym: 野黄芩素,4',5,6,7-Tetrahydroxyflavone,6-Hydroxyapigenin
Target: SARS-CoV, Src, Autophagy
Corticosterone
Cat.No: T0948L
Synonym: 皮质酮,17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,肾上腺酮,Corticosterone (From plants)
Target: Glucocorticoid Receptor, Endogenous Metabolite
Ascr#5
Cat.No: T13557
Synonym: Ascaroside C3
Target: Others
5-Methoxy-DL-tryptophan
Cat.No: T5235
Synonym:
Target: Others, Endogenous Metabolite
Taurodeoxycholate sodium salt
Cat.No: TN2349
Synonym: Sodium taurodeoxylate,牛磺脱氧胆酸钠
Target: Endogenous Metabolite
Lindleyin
Cat.No: TN1052
Synonym:
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor
DL-Syringaresinol
Cat.No: TN1594
Synonym: (±)-Syringaresinol
Target: Antioxidant, Antifungal
N-trans-caffeoyltyramine
Cat.No: TN6457
Synonym: Trans-N-Caffeoyltyramine,N-(E)-Caffeoyl-lambda-tyramine,N-cis-Caffeoyltyramine,Typheramide
Target: Immunology/Inflammation related
Ascr#2
Cat.No: T13555
Synonym: Ascaroside C6
Target: Others
3-Indoleacrylic acid
Cat.No: T67710
Synonym:
Target: Endogenous Metabolite
1-Kestose
Cat.No: T5731
Synonym: 蔗果三糖,1-蔗果三糖
Target: Others, Endogenous Metabolite, Antibacterial
Tangeretin
Cat.No: T2842
Synonym: NSC53909,Tangeritin,NSC618905,桔皮素
Target: Apoptosis, Gamma-secretase
Lucideric acid A
Cat.No: TN1879
Synonym: Lucidenic acid A,赤芝酸A
Target: MMP, p38 MAPK, JNK
Isorhynchophylline
Cat.No: T6S0657
Synonym: IsoRhy,异钩藤碱,Isorhyncophylline,Isorhychophylline,7-Isorhyncophylline
Target: Others
Kaempferol-3-O-glucorhamnoside
Cat.No: T5S0089
Synonym: Kaempferol 3-glucorhamnoside,百蕊草素I
Target: Antioxidant, p38 MAPK, NF-κB
Indole-3-pyruvic acid
Cat.No: T4939
Synonym: 3-(3-吲哚基)-2-氧代丙酸,3-(3-Indolyl)-2-oxopropanoic acid
Target: Others
Hydrocortisone
Cat.No: T1614
Synonym: 氢化可的松,Cortisol
Target: Glucocorticoid Receptor, Endogenous Metabolite
Euscaphic acid
Cat.No: TN1134
Synonym:
Target: Apoptosis, LDL, PI3K, DNA/RNA Synthesis, NO Synthase, Prostaglandin Receptor
Kurarinone
Cat.No: T5S0993
Synonym: 苦参酮,苦参黄素
Target: BCL, Others, IκB/IKK, TNF, NF-κB, JAK, STAT
6-Benzylaminopurine
Cat.No: T1004
Synonym: 6-苄氨基嘌呤,6-BAP,N6-Benzyladenine,BA,Benzyladenine
Target: Others
Emodin 6-O-β-D-glucoside
Cat.No: TN6774
Synonym: 大黄素-6-O-β-D-葡萄糖苷,Glucoemodin
Target: Others
Norisoboldine
Cat.No: T5S1895
Synonym: Laurelliptine,去甲异波尔定,(+)-Laurelliptine
Target: MAPK, Adenosine Receptor
L-Kynurenine
Cat.No: T4928
Synonym: L-犬尿氨酸,(S)-Kynurenine
Target: AhR, Aryl Hydrocarbon Receptor, Endogenous Metabolite
Aloin B
Cat.No: T5S1177
Synonym: Isobarbaloin,芦荟苷B,芦荟素B
Target: Others
Isotretinoin
Cat.No: T1611
Synonym: 13-cis-Retinoic acid,异维A酸
Target: Retinoid Receptor, Endogenous Metabolite, Autophagy
(+)-Columbianetin
Cat.No: T5S1286
Synonym: 二氢山芹醇,(S)-Columbianetin,Columbianetin
Target: Antifungal
Kaempferitrin
Cat.No: T3386
Synonym: Lespedin,Kaempferol,Lespenephryl,Lespenefril,Kaempferol 3,7-dirhamnoside,山奈苷
Target: cell cycle arrest, Glucokinase, IGF-1R
L-Arginine
Cat.No: T3S0364
Synonym: L-精氨酸,L-Arg,(S)-(+)-Arginine
Target: IL Receptor, Endogenous Metabolite, NO Synthase
Esculentoside A
Cat.No: T3877
Synonym:
Target: NF-κB, COX
gamma-Linolenic acid
Cat.No: T4868
Synonym: gamolenic acid,γ-Linolenic acid,γ-亚麻酸
Target: Endogenous Metabolite
Lipopolysaccharides
Cat.No: T11855
Synonym: 脂多糖,LPS
Target: Others
Flavokawain A
Cat.No: T3S0737
Synonym: 2'-羟基-4,4',6'-三甲氧基查耳酮,Flavokavain A
Target: Apoptosis, p38 MAPK
Mollugin
Cat.No: T3673
Synonym: 大叶茜草素,Rubimaillin
Target: HER, JAK
Ginkgetin
Cat.No: T4S2126
Synonym: 银杏双黄酮,银杏素
Target: Apoptosis, Wnt/beta-catenin, COX, STAT, Autophagy
Lipopolysaccharides, Escherichiacoli
Cat.No: T41078
Synonym: Lipopolysaccharide, E. coli O111:B4
Target: Others
Cornuside
Cat.No: T4S2326
Synonym: 7-Galloylsecologanol,7-O-Galloylsecologanol,山茱萸新苷,Comuside
Target: ERK, p38 MAPK, NF-κB, JNK
Thymohydroquinone
Cat.No: T35749
Synonym: Thymoquinol
Target: Antioxidant, Reactive Oxygen Species
Platycoside A
Cat.No: TN4804
Synonym:
Target: Antifection
Grandiflorenic acid
Cat.No: T20217
Synonym:
Target: Others
Quinine HCl
Cat.No: TN4882
Synonym: 奎宁树
Target: Adrenergic Receptor
β-Tomatine
Cat.No: T39179
Synonym:
Target: Others
Bakkenolide B
Cat.No: TN3482
Synonym:
Target: NOS, COX
Xanthoplanine
Cat.No: T13968
Synonym:
Target: Others
Latifolin
Cat.No: TN4420
Synonym: 檀木
Target: IL Receptor, IκB/IKK, TNF, NOS, NF-κB, COX, Nrf2, Prostaglandin Receptor, Antifection, Autophagy
(+)-Dihydrocarvone
Cat.No: T83600
Synonym:
Target:
Methyl 7(Z)-hexadecenoate
Cat.No: TN7276
Synonym: Methyl cis-7-hexadecenoate
Target: Others
Cyclo(his-pro) TFA
Cat.No: T61171
Synonym:
Target: Others
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Cat. No. Product Name Species Expression System
TMPK-00047 IFN gamma Protein, Human, Recombinant (His & Avi)

IFN gamma,interferon,Interferon-γ,γ,IFI,干扰素,Interferon-gamma...

Human HEK293 Cells
Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma production or cellular responsiveness in humans and experimental animals significantly predisposes the host to microbial infection, a result that validates the physiologic importance of this cytokine in preventing infectious disease. IFN gamma Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi ...
TMPK-00022 Galectin-1 Protein, Human, Recombinant (hFc)

GAL1,LGALS1,Galectin-1,S-Lac lectin 1,DKFZp686E23103,GBP,Gal...

Human HEK293 Cells
Galectin 1 (Gal-1), a β-galactoside binding mammalian lectin of 14KDa, is implicated in many signalling pathways, immune responses associated with cancer progression and immune disorders. Inhibition of human Gal-1 has been regarded as one of the potential therapeutic approaches for the treatment of cancer, as it plays a major role in tumour development and metastasis by modulating various biological functions viz. apoptosis, angiogenesis, migration, cell immune escape.
TMPJ-00735 PDGF-BB Protein, Human, Recombinant

PDGF-BB,血小板源生长因子,PDGFBB

Human E. coli
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In a...
TMPJ-00864 VEGF165 Protein, Human, Recombinant

Vascular Endothelial Growth Factor Isoform 165,血管内皮生长因子,VEGF...

Human HEK293 Cells
Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator in vasculogenesis and angiogenesis both physiologically and pathologically. VEGF-A has 8 differently spliced isoforms, of which VEGF165 is the most abundant one. VEGF165 is a disulfide-linked homodimer consisting of two glycosylated 165 amino acid polypeptide chains. VEGF stimul...
TMPY-05510 BDNF Protein, Mouse, Recombinant (His)

brain-derived neurotrophic factor

Mouse HEK293 Cells
BDNF is a member of thenerve growth factorfamily. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. It participates in axonal growth,...
TMPY-02603 STAT6 Protein, Human, Recombinant (His)

STAT6C,IL-4-STAT,STAT6B,signal transducer and activator of t...

Human Baculovirus Insect Cells
Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6 plays a central role in exerting interleukin-4 (IL-4) mediated biological responses and is found to induce the expression of BCL2L1/BCL-XL, which is responsible for the anti-apoptotic activity of IL4. Transcriptional activation by STAT6 requires the interaction with coactivators...
TMPJ-01204 TPSAB1 Protein, Human, Recombinant (His)

TPS1,tryptase alpha/beta 1,TPS2,tryptase α/β1,tryptase α/β 1...

Human HEK293 Cells
Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase alpha/beta-1(TPSAB1), also known as mast cell protease 7 (MCPT7), it exhibits anticoagulant activity due to its ability to degrade fibrinogen in the presence of a diverse array of protease inhibitors in plasma. The two Isoform 1 and isoform 2 are expressed in lung, stomach, spleen, heart and s...
TMPY-02904 TLR4 Protein, Human, Recombinant (His)

TLR-4,TOLL,toll-like receptor 4,ARMD10,TLR4,CD284

Human Baculovirus Insect Cells
TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. TLR4 is most abundantly expressed...
TMPY-06981 IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)

interleukin 1 α,IL1,白介素,IL-1F1,IL1-α,IL-1A,IL1F1,白细胞介素,IL-1 ...

Human E. coli
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophage...
TMPJ-00387 IL-4R alpha Protein, Mouse, Recombinant (hFc)

Soluble IL-4R-alpha,Interleukin-4 receptor subunit alpha,Sol...

Mouse HEK293 Cells
Interleukin-4 receptor subunit alpha(IL-4RA), alos known as Soluble IL-4 receptor subunit alpha, belongs to the type I cytokine receptor family and type 4 subfamily. It expressed in both Th1 and Th2 cells. It functions as receptor for both interleukin 4 and interleukin 13 and couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and chemokine and mucus production at sites of allergic ...
TMPJ-00137 APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)

TRDL-1,TNF- and APOL-related leukocyte expressed ligand 2,Tu...

Human HEK293 Cells
APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. Secreted human APRIL, which consists almost entirely of a single TNF homology domain, shares 85% amino acid sequence identity with mouse and rat APRIL. Both APRIL and its close relative BAFF bind and signal through the TNF superfamily recept...
TMPY-02153 TNF beta Protein, Human, Recombinant

LT,TNF β,TNFSF1,肿瘤坏死因子,TNFB,lymphotoxin alpha,lymphotoxin α

Human E. coli
Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lymphotoxin alpha is highly inducible, secreted, and exists as a homotrimeric molecule. It is a cytokine that in its homotrimeric form binds to TNFRSF1A / TNFR1, TNFRSF1B / TNFBR, and TNFRSF14 / HVEM. In its heterotrimeric form with LTB, TNF-beta/TNFSF1/Lymphotoxin alpha binds to TNFRS...
TMPY-04552 AKT1 Protein, Human, Recombinant (His)

RAC-ALPHA,v-akt murine thymoma viral oncogene homolog 1,RAC,...

Human Baculovirus Insect Cells
v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to insulin, insulin-like growth factor 1 (IGF1), and glucose. AKT1 also plays a key role in the regulation of both muscle cell hypertrophy and atrophy. AKT1 activity is required for physiologic cardiac growth in response to IGF1 stimulation or exercise training. In contrast, AKT1 ac...
TMPJ-00042 TSLP Protein, Human, Recombinant

TSLP,Thymic stromal lymphopoietin

Human E. coli
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino acids (aa) signal sequence and 131 aa mature region. Human TSLP has two isoforms lfTSLP and sfTSLP produced by alternative splicing . lfTSLP is expressed in a number of tissues including heart, liver and prostate, and sfTSLP (63aa) is predominantly expressed in keratinocytes of oral...
TMPY-02550 Eotaxin/CCL11 Protein, Human, Recombinant (His)

SCYA11,chemokine (C-C motif) ligand 11

Human E. coli
CCL11 or chemokine (C-C motif) ligand 11 is a member of the chemokine (C-C motif) ligand family. Chemokin (C-C motif) ligand 11 is a member of the chemokine family. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands (CCL)-1 to 28. Chemokines are a family of small ...
TMPY-04483 IRAK4 Protein, Human, Recombinant (His)

IPD1,NY-REN-64,REN64,interleukin-1 receptor-associated kinas...

Human Baculovirus Insect Cells
Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4 contains one death domain and one protein kinase domain. IRAK4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. ...
TMPY-02219 Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)

NS1 Protein

H1N1 E. coli
The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the NS2 protein, which mediates the export of vRNPs. The non-structural (NS1) protein is found in Influenzavirus A, Influenzavirus B, and Influenzavirus C. The non-structural (NS1) protein of the highly pathogenic avian H5N1 viruses circulating in poultry and waterfowl in Southeast As...
TMPY-03443 NDRG1 Protein, Human, Recombinant (His)

TARG1,PROXY1,RIT42,NDR1,DRG1,RTP,TDD5,CMT4D,CAP43,NMSL,N-myc...

Human E. coli
NDRG1 gene is a member of the N-Myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. NDRG1 is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. NDRG1 is necessary for p53-mediated caspase activation and apoptosis. Mutations in the NDRG1 gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. NDRG1 is a stress-responsive pro...
TMPJ-00446 CD32A Protein, Human, Recombinant (R167, His)

FcRII-a,IGFR2,Low Affinity Immunoglobulin Gamma Fc Region Re...

Human HEK293 Cells
Receptors for the Fc region of IgG (FcγR) are members of the Ig superfamily that function in the activation or inhibition of immune responses. Human FcγRs are divided into three classes designated FcγRI (CD64), FcγRII (CD32), and FcγRIII (CD16), which generate multiple isoforms, are recognized. The activating­ type receptor either has or associates non­covalently with an accessory subunit that has an immunoreceptor tyrosine­based activation motif (ITAM) in its cytoplasmic domain. FcγRI binds IgG...
TMPK-00123 CD8 alpha Protein, Human, Recombinant (aa 22-182, His & Avi), Biotinylated

Leu2,CD8 α/CD8A,MAL,Lyt-2,OKT8 T-cell antigen,CD8a molecule,...

Human HEK293 Cells
CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8 alpha is also found on dendritic cells and rat macrophages, but whether CD8 alpha enhances responses of a partner receptor, like TCR, to activate these cells is not known.
TMPH-01542 ITIH4 Protein, Human, Recombinant (His & SUMO)

Inter-alpha-trypsin inhibitor heavy chain H4,ITIH4,Plasma ka...

Human E. coli
Type II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver development or regeneration.
TMPH-02688 Granzyme C/GZMC Protein, Mouse, Recombinant (His & Myc)

Cytotoxic cell protease 2,B10,Gzmc,Granzyme C

Mouse E. coli
This enzyme is probably necessary for target cell lysis in cell-mediated immune responses. Granzyme C/GZMC Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 32.6 kDa and the accession number is P08882.
TMPH-01541 ITIH4 Protein, Human, Recombinant (His)

ITIH4,Inter-alpha-trypsin inhibitor heavy chain H4,Inter-alp...

Human P. pastoris (Yeast)
Type II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver development or regeneration.
TMPK-00698 AGR2 Protein, Mouse, Recombinant (His)

AG2,HPC8,hAG-2,Anterior gradient protein 2 homolog,AG-2,hAG ...

Mouse E. coli
Anterior gradient homolog 2 (AGR2) is a functional protein with critical roles in a diverse range of biological systems, including vertebrate tissue development, inflammatory tissue injury responses, and cancer progression.
TMPH-01717 CHRM5 Protein, Human, Recombinant (His)

CHRM5,Muscarinic acetylcholine receptor M5

Human E. coli
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. CHRM5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.5 kDa and the accession number is P08912.
TMPJ-00030 IL-1F10 Protein, Human, Recombinant

Interleukin-1 Family Member 10,白介素,Interleukin-1 HY2,FIL1T,F...

Human E. coli
Human Interleukin 1 Family Member 10 (IL-1F10) is thought to participate in a network of Interleukin 1 cytokine family members to regulate adapted and innate immune responses. IL-1F10 was expressed in fetal skin, spleen and tonsil, mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil. IL-1F10 binds soluble IL-1 receptor type 1 and may be implicated in regulating adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protei...
TMPH-03338 CHRM1 Protein, Rat, Recombinant (His)

Muscarinic acetylcholine receptor M1,CHRM1

Rat E. coli
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. CHRM1 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.1 kDa and the accession number is P08482.
TMPK-01543 HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (His & Avi)

LAGE2A,ESO1CTAG,LAGE-2,CTAG1,CT6.1,MHC,MY-ESO-1,NY-ESO-1,CTA...

Human HEK293 Cells
NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPK-01499 HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Tetramer Protein, Human, MHC (His & Avi)

ESO1CTAG,LAGE-2,CTAG1B,LAGE2A,MY-ESO-1,CT6.1,NY-ESO-1,CTAG1,...

Human HEK293 Cells
NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPK-01497 HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

MY-ESO-1,MHC,ESO1CTAG,NY-ESO-1,CTAG1,LAGE2A,LAGE-2,CT6.1,CTA...

Human HEK293 Cells
NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPH-01716 CHRM3 Protein, Human, Recombinant (B2M & His)

Muscarinic acetylcholine receptor M3,CHRM3

Human E. coli
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. CHRM3 Protein, Human, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 40.7 kDa and the accession number is P20309.
TMPK-00598 Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi), Biotinylated

Fc gamma RIIIA,Fc γ RIIIA,FCGR3,FcRIII,FCG3,IGFR3,FCGR3A,FcR...

Human HEK293 Cells
The Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.
TMPK-01500 HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Monomer Protein, Human, MHC (His & Avi)

CTAG1,CT6.1,CTAG1B,LAGE2A,MY-ESO-1,LAGE-2,MHC,NY-ESO-1,ESO1C...

Human HEK293 Cells
NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPK-01539 HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (His & Avi), Biotinylated

CTAG1B,CT6.1,MY-ESO-1,LAGE2A,NY-ESO-1,MHC,LAGE-2,ESO1CTAG,CT...

Human HEK293 Cells
NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPK-01449 HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (E. coli, His & Avi)

MHC,CT6.1,CTAG1,LAGE-2,MY-ESO-1,NY-ESO-1,ESO1CTAG,LAGE2A,CTA...

Human E. coli
NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPK-01040 NKG2C/CD159c Protein, Cynomolgus, Recombinant (His)

NKG2C,NK cell receptor C,CD159c,KLRC2

Cynomolgus HEK293 Cells
As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections. The presented study is the first of its kind that ascribes CD56dimCD16 NKG2C-expressing NK cells a crucial role in biasing adaptive immune responses upon influenza vaccination and suggests NKG2C as a potential biomarker in predicting pandemic influenza vaccine responsiveness.
TMPK-01230 CLEC2D Protein, Human, Recombinant (hFc & Avi)

Lectin-like NK cell receptor,LLT-1,OCIL,LLT1,Lectin-like tra...

Human HEK293 Cells
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Pre-eclampsia and HIV infection have opposing immune responses. The contrasting expression of CLEC2D in HIV infection and pre-eclampsia is demonstrative of the immunosuppressive and pro-inflammatory roles of the respective pathologies. However, this implication may be confounded by highly active anti-retroviral treatment (HAART).
TMPK-00599 Fc gamma RIIIA/CD16a (V176) Domain 2 Protein, Human, Recombinant (mFc)

FCGR3,IGFR3,FcR-10,Fc γ RIIIA/CD16a (V176) Domain 2 Protein,...

Human HEK293 Cells
Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. Fc gamma RIIIA/CD16a (V176) Domain 2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 35.29 kDa and the accession number is AAH17865.
TMPH-03332 OPN4 Protein, Rat, Recombinant (His)

Opn4,Melanopsin,Opsin-4

Rat E. coli
Photoreceptor that binds cis-retinaldehydes. Contributes to pupillar reflex, photoentrainment and other non-image forming responses to light. May be involved in the optokinetic visual tracking response. May be involved in the regulation of retinal hyaloid vessel growth and regression. OPN4 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 53.9 kDa and the accession number is Q8R456.
TMPH-01714 CHRM1 Protein, Human, Recombinant (His)

Muscarinic acetylcholine receptor M1,CHRM1

Human E. coli
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. CHRM1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 20.8 kDa and the accession number is P11229.
TMPK-01192 Varicella-zoster virus (strain Oka vaccine) Envelope glycoprotein E Protein (His)

Envelope glycoprotein E,ORF68,gE

Varicella-zoster virus (strain Oka vaccine) HEK293 Cells
VZV glycoprotein E (gE) is most abundantly expressed on the surface of infected cells, and is an essential component for virus replication and cell-to-cell transmission. It is also the main target of virus-specific antibodies and T cell responses that is often selected as vaccine candidate antigen.
TMPK-01231 CLEC2D Protein, Human, Recombinant (hFc & Avi), Biotinylated

OCILmember D,LLT1,CLAX,CLEC2D,CLAXLLT-1,LLT-1,OCIL

Human HEK293 Cells
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Pre-eclampsia and HIV infection have opposing immune responses. The contrasting expression of CLEC2D in HIV infection and pre-eclampsia is demonstrative of the immunosuppressive and pro-inflammatory roles of the respective pathologies.
TMPK-00565 PSGL-1/CD162 Protein, Cynomolgus, Recombinant (His)

PSGL-1,CD162,SELPLG,PSGL1,Selectin P ligand,Selpl,CLA,Selp1

Cynomolgus HEK293 Cells
P-selectin glycoprotein ligand-1 (PSGL-1) has long been studied as an adhesion molecule involved in immune cell trafficking and is recognized as a regulator of many facets of immune responses by myeloid cells. PSGL-1 also regulates T cell migration during homeostasis and inflammatory settings. PSGL-1/CD162 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 34.57 kDa and the accession number is A0A7N9CVJ8.
TMPK-00970 FGL2 Protein, Human, Recombinant (hFc & Flag)

pT49,fibrinogen-like 2,Fibroleukin,FGL2

Human HEK293 Cells
Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immune responses. FGL2 is overexpressed in glioma, and its expression level is negatively associated with the prognosis of glioma patients. FGL2 Protein, Human, Recombinant (hFc & Flag) is expressed in HEK293 mammalian cells with N-hFc-Flag tag. The predicted molecular weight is 54.73 kDa and the accession number is Q14314.
TMPK-00829 Galectin-1 Protein, Mouse, Recombinant (hFc)

GBP,DKFZp686E23103,S-Lac lectin 1,GAL1,Galectin-1,HLBP14,LGA...

Mouse HEK293 Cells
Galectin 1(Gal-1), a β-galactoside binding mammalian lectin of 14KDa, is implicated in many signalling pathways, immune responses associated with cancer progression and immune disorders. Inhibition of human Gal-1 has been regarded as one of the potential therapeutic approaches for the treatment of cancer, as it plays a major role in tumour development and metastasis by modulating various biological functions viz. apoptosis, angiogenesis, migration, cell immune escape.
TMPH-02879 REG3G Protein, Mouse, Recombinant (His)

Regenerating islet-derived protein III-gamma,Reg3g,Pancreati...

Mouse P. pastoris (Yeast)
Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regula...
TMPK-00536 FGL2 Protein, Cynomolgus, Recombinant (His & Avi, Flag), Biotinylated

Fibroleukin,pT49,FGL2,fibrinogen-like 2

Cynomolgus HEK293 Cells
Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immune responses. FGL2 is overexpressed in glioma, and its expression level is negatively associated with the prognosis of glioma patients. FGL2 Protein, Cynomolgus, Recombinant (His & Avi, Flag), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi and N-Flag tag. The predicted molecular weight is 31.40 kDa and the accession nu...
TMPK-00439 SARS-COV-2 Spike RBD Protein (His & Avi), Biotinylated

S protein RBD,S glycoprotein RBD,Spike protein RBD

SARS-CoV-2 HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike RBD Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27 kDa and the accession nu...
TMPK-00912 SARS Spike RBD Protein (His & Avi), Biotinylated

S glycoprotein RBD,S protein RBD,Spike protein RBD

SARS HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS Spike RBD Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27.9 kDa and the accession number...
TMPK-00814 FGL2 Protein, Mouse, Recombinant (His & Avi, Flag), Biotinylated

FGL2,Fibroleukin,fibrinogen-like 2,pT49

Mouse HEK293 Cells
Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immune responses. FGL2 is overexpressed in glioma, and its expression level is negatively associated with the prognosis of glioma patients. FGL2 Protein, Mouse, Recombinant (His & Avi, Flag), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi and N-Flag tag. The predicted molecular weight is 31.48 kDa and the accession number ...
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重组蛋白

IFN gamma Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00047
Species: Human
Expression System: HEK293 Cells
Galectin-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00022
Species: Human
Expression System: HEK293 Cells
PDGF-BB Protein, Human, Recombinant
Cat.No: TMPJ-00735
Species: Human
Expression System: E. coli
VEGF165 Protein, Human, Recombinant
Cat.No: TMPJ-00864
Species: Human
Expression System: HEK293 Cells
BDNF Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05510
Species: Mouse
Expression System: HEK293 Cells
STAT6 Protein, Human, Recombinant (His)
Cat.No: TMPY-02603
Species: Human
Expression System: Baculovirus Insect Cells
TPSAB1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01204
Species: Human
Expression System: HEK293 Cells
TLR4 Protein, Human, Recombinant (His)
Cat.No: TMPY-02904
Species: Human
Expression System: Baculovirus Insect Cells
IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)
Cat.No: TMPY-06981
Species: Human
Expression System: E. coli
IL-4R alpha Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00387
Species: Mouse
Expression System: HEK293 Cells
APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)
Cat.No: TMPJ-00137
Species: Human
Expression System: HEK293 Cells
TNF beta Protein, Human, Recombinant
Cat.No: TMPY-02153
Species: Human
Expression System: E. coli
AKT1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04552
Species: Human
Expression System: Baculovirus Insect Cells
TSLP Protein, Human, Recombinant
Cat.No: TMPJ-00042
Species: Human
Expression System: E. coli
Eotaxin/CCL11 Protein, Human, Recombinant (His)
Cat.No: TMPY-02550
Species: Human
Expression System: E. coli
IRAK4 Protein, Human, Recombinant (His)
Cat.No: TMPY-04483
Species: Human
Expression System: Baculovirus Insect Cells
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)
Cat.No: TMPY-02219
Species: H1N1
Expression System: E. coli
NDRG1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03443
Species: Human
Expression System: E. coli
CD32A Protein, Human, Recombinant (R167, His)
Cat.No: TMPJ-00446
Species: Human
Expression System: HEK293 Cells
CD8 alpha Protein, Human, Recombinant (aa 22-182, His & Avi), Biotinylated
Cat.No: TMPK-00123
Species: Human
Expression System: HEK293 Cells
ITIH4 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01542
Species: Human
Expression System: E. coli
Granzyme C/GZMC Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02688
Species: Mouse
Expression System: E. coli
ITIH4 Protein, Human, Recombinant (His)
Cat.No: TMPH-01541
Species: Human
Expression System: P. pastoris (Yeast)
AGR2 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00698
Species: Mouse
Expression System: E. coli
CHRM5 Protein, Human, Recombinant (His)
Cat.No: TMPH-01717
Species: Human
Expression System: E. coli
IL-1F10 Protein, Human, Recombinant
Cat.No: TMPJ-00030
Species: Human
Expression System: E. coli
CHRM1 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03338
Species: Rat
Expression System: E. coli
HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01543
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01499
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
Cat.No: TMPK-01497
Species: Human
Expression System: HEK293 Cells
CHRM3 Protein, Human, Recombinant (B2M & His)
Cat.No: TMPH-01716
Species: Human
Expression System: E. coli
Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00598
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01500
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01539
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (E. coli, His & Avi)
Cat.No: TMPK-01449
Species: Human
Expression System: E. coli
NKG2C/CD159c Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01040
Species: Cynomolgus
Expression System: HEK293 Cells
CLEC2D Protein, Human, Recombinant (hFc & Avi)
Cat.No: TMPK-01230
Species: Human
Expression System: HEK293 Cells
Fc gamma RIIIA/CD16a (V176) Domain 2 Protein, Human, Recombinant (mFc)
Cat.No: TMPK-00599
Species: Human
Expression System: HEK293 Cells
OPN4 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03332
Species: Rat
Expression System: E. coli
CHRM1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01714
Species: Human
Expression System: E. coli
Varicella-zoster virus (strain Oka vaccine) Envelope glycoprotein E Protein (His)
Cat.No: TMPK-01192
Species: Varicella-zoster virus (strain Oka vaccine)
Expression System: HEK293 Cells
CLEC2D Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPK-01231
Species: Human
Expression System: HEK293 Cells
PSGL-1/CD162 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00565
Species: Cynomolgus
Expression System: HEK293 Cells
FGL2 Protein, Human, Recombinant (hFc & Flag)
Cat.No: TMPK-00970
Species: Human
Expression System: HEK293 Cells
Galectin-1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-00829
Species: Mouse
Expression System: HEK293 Cells
REG3G Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02879
Species: Mouse
Expression System: P. pastoris (Yeast)
FGL2 Protein, Cynomolgus, Recombinant (His & Avi, Flag), Biotinylated
Cat.No: TMPK-00536
Species: Cynomolgus
Expression System: HEK293 Cells
SARS-COV-2 Spike RBD Protein (His & Avi), Biotinylated
Cat.No: TMPK-00439
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS Spike RBD Protein (His & Avi), Biotinylated
Cat.No: TMPK-00912
Species: SARS
Expression System: HEK293 Cells
FGL2 Protein, Mouse, Recombinant (His & Avi, Flag), Biotinylated
Cat.No: TMPK-00814
Species: Mouse
Expression System: HEK293 Cells
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Cat. No. Product Name Target Signaling Pathways
TMID-0229 Cortisol-1,2-d2

Cortisol-1,2-d2 是 Cortisol 的氘代化合物。Cortisol 的 CAS 号为 50-23-7。Hydrocortisone 是肾上腺皮质分泌的糖皮质激素。
T71206 Tiagabine-d6 hydrochloride

Tiagabine-d6 is intended for use as an internal standard for the quantification of tiagabine by GC- or LC-MS. Tiagabine is an inhibitor of GABA transporter 1. It inhibits seizures induced by DMCM in mice. Tiagabine reduces allodynia in a rodent model of neuropathic pain when used at a dose of 72.8 µmol/kg, and it acts synergistically with gabapentin to delay pain responses in mice in the hot plate test. Formulations containing tiagabine have been used as adjunctive therapies in the treatment of ...
TMIJ-0193 Hydrocortisone-d4

Hydrocortisone-d4 是 Hydrocortisone 的氘代化合物。Hydrocortisone 的 CAS 号为 50-23-7。Hydrocortisone 是肾上腺皮质分泌的糖皮质激素。
TMIJ-0162 Dexamethasone-d4

Dexamethasone-d4 是 Dexamethasone 的氘代化合物。Dexamethasone 的 CAS 号为 50-02-2。Dexamethasone是一种糖皮质激素受体激动剂和一种 IL 受体调节剂。在脂多糖诱导的巨噬细胞炎症反应中,它抑制含有炎性 microRNA-155 的外泌体的产生。
T71065 Quinapril-d5

Quinapril-d5 is intended for use as an internal standard for the quantification of quinapril by GC- or LC-MS. Quinapril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor quinaprilat. In vivo, quinapril reduces mean arterial pressure in renal hypertensive and spontaneously hypertensive rats. It inhibits angiotensin I-induced pressor responses in normotensive rats and dogs. Quinapril prevents left ventricular heart failure in CHF 14.6 cardiomyopathic hamsters. Formulations con...
T71205 Fosinopril-d7 sodium salt

Fosinopril-d7 is intended for use as an internal standard for the quantification of fosinopril by GC- or LC-MS. Fosinopril is a prodrug form of the angiotensin-converting enzyme inhibitor fosinoprilat. Oral administration of fosinopril inhibits angiotensin I-induced pressor responses in normotensive rats, dogs, and monkeys when administered at doses of 15, 15, and 10 µmol/kg, respectively. Fosinopril reduces fractional shortening and decreases left ventricular size in a porcine model of congesti...
T70394 Deucravacitinib HCl

Deucravacitinib HCl is a Highly Potent and Selective Allosteric Inhibitor of TYK2. BMS-986165 Blocks Il-12, IL-23 and type I Interferon Signaling and Provides for Robust Efficacy in Preclinical Models of Inflammatory Bowel Disease. MS-986165 potently binds to the Tyk2 pseudokinase domain (Ki = 0.02 nM), and is highly selective against a panel of 265 kinases and pseudokinases. The compound potently inhibited IL-23-, IL-12-, and Type I interferon-driven cellular signaling and transcriptional resp...
TMIJ-0518 L-Kynurenine-d4-1

L-Kynurenine-d4-1 是 L-Kynurenine 的氘代化合物。L-Kynurenine 的 CAS 号为 2922-83-0。L-Kynurenine是L-色氨酸的代谢物,是芳香烃受体激动剂,可抑制同种异体 T 细胞增殖并增加恶性 U87 神经胶质瘤细胞侵入胶原基质。
TMID-0071 L-Kynurenine-d4

L-Kynurenine-d4 是 L-Kynurenine 的氘代化合物。L-Kynurenine 的 CAS 号为 2922-83-0。L-Kynurenine是L-色氨酸的代谢物,是芳香烃受体激动剂,可抑制同种异体 T 细胞增殖并增加恶性 U87 神经胶质瘤细胞侵入胶原基质。
TMIH-0046 3-Indoleacrylic acid-d4

3-Indoleacrylic acid-d4 是 3-Indoleacrylic acid 的氘代化合物。3-Indoleacrylic acid 的 CAS 号为 1204-06-4。3-Indoleacrylic acid是由链球菌属产生的色氨酸的代谢产物。3-Indoleacrylic acid对肠上皮屏障功能有有益作用,并减轻免疫细胞的炎症反应。
TMID-0294 Taurodeoxycholic Acid-d4 Sodium Salt

Taurodeoxycholic Acid-d4 Sodium Salt 是 Taurodeoxycholic Acid Sodium Salt 的氘代化合物。Taurodeoxycholic Acid Sodium Salt 的 CAS 号为 1180-95-6。Taurodeoxycholate sodium salt 是胆盐相关的阴离子洗涤剂,用于分离膜蛋白,包括线粒体内膜蛋白。它还可以抑制各种炎症反应。
TMIJ-0272 Sarpogrelate-d3 HCl

Sarpogrelate-d3 HCl 是 Sarpogrelate HCl 的氘代化合物。Sarpogrelate HCl 的 CAS 号为 135159-51-2。Sarpogrelate hydrochloride 是一种选择性5-HT2R拮抗剂,可用于研究与血栓形成有关的血管疾病,对 5-HT2A、5-HT2B 和 5-HT2C 受体的pKi值分别为 8.52、6.57 和 7.43。
TMIJ-0044 Carbamazepine-d10

Carbamazepine-d10 是 Carbamazepine 的氘代化合物。Carbamazepine 的 CAS 号为 298-46-4。Carbamazepine是与三环抗抑郁药化学相关的三环化合物,具有抗惊厥和镇痛特性。它通过减少多突触反应和阻断强直后增强发挥其抗惊厥活性。 它通常用于治疗与三叉神经痛相关的疼痛。
T38356 1,2-Dipalmitoyl-13C-sn-glycero-3-PC

1,2-Dipalmitoyl-13C-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PC by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PC (DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes for use in a variety of applications.1,2,3,4 It has been used in the formation of proteoliposomes for implantation of γ-glutamyl transpeptidase into human erythrocyte membranes.3 Incorporation...

同位素标记化合物

Cortisol-1,2-d2
Cat.No: TMID-0229
Synonym:
Target:
Tiagabine-d6 hydrochloride
Cat.No: T71206
Synonym:
Target:
Hydrocortisone-d4
Cat.No: TMIJ-0193
Synonym:
Target:
Dexamethasone-d4
Cat.No: TMIJ-0162
Synonym:
Target:
Quinapril-d5
Cat.No: T71065
Synonym:
Target:
Fosinopril-d7 sodium salt
Cat.No: T71205
Synonym:
Target:
Deucravacitinib HCl
Cat.No: T70394
Synonym:
Target:
L-Kynurenine-d4-1
Cat.No: TMIJ-0518
Synonym:
Target:
L-Kynurenine-d4
Cat.No: TMID-0071
Synonym:
Target:
3-Indoleacrylic acid-d4
Cat.No: TMIH-0046
Synonym:
Target:
Taurodeoxycholic Acid-d4 Sodium Salt
Cat.No: TMID-0294
Synonym:
Target:
Sarpogrelate-d3 HCl
Cat.No: TMIJ-0272
Synonym:
Target:
Carbamazepine-d10
Cat.No: TMIJ-0044
Synonym:
Target:
1,2-Dipalmitoyl-13C-sn-glycero-3-PC
Cat.No: T38356
Synonym:
Target:
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