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Search Results for " inducer "
Targets Recommended: Others

212

抑制剂 & 化合物

52

天然产物

19

重组蛋白

2

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T7262 Methuosis inducer 1

Others Others
Methuosis inducer 1 是methuosis 诱导剂,表现出抗肿瘤特性。
T30480 BiP inducer X

BIX

Apoptosis Apoptosis
BiP inducer X (BIX) 是免疫球蛋白重链结合蛋白 (BiP)/GRP78 的选择性诱导剂和 ER 伴侣诱导剂。 BiP inducer X 可防止神经元和视网膜细胞系中的细胞死亡。
T13809 P62-mediated mitophagy inducer

PMI

Mitophagy Autophagy
P62-mediated mitophagy inducer (PMI) 是一种线粒体自噬调节剂,能激活线粒体自噬,可在缺乏完整功能的 PINK1/Parkin 通路的细胞中保留活性。
T13736 Interferon receptor inducer-1

IFNAR Immunology/Inflammation
Interferon receptor inducer-1 是一种干扰素(IFN)受体诱导剂,可用于干扰素诱导参与的紊乱性疾病的研究。
T8871 C/EBPα inducer 1

4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-

Others Others
C/EBPα inducer 1 (4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-) 是一种C/EBPα和骨髓细胞分化的诱导剂。
T3221 Oct3/4-inducer-1

2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile,2-(4-[(4-甲氧基苄基)氧基]苯基)乙腈

Others; OCT Membrane transporter/Ion channel; Others
Oct3/4-inducer-1 (2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile) 是Oct3/4诱导剂,能够促进 Oct3/4 的表达和稳定,提高其在多种人体细胞中的转录活性。
T77753 EBV lytic cycle inducer-1

Dp44mT

Antifection Microbiology/Virology
EBV lytic cycle inducer-1 是一种铁螯合类似物,可诱导EBV 裂解循环。
T77574 ROS inducer 1

ROS; Antibiotic Immunology/Inflammation; Microbiology/Virology
ROS inducer 1 是一种具有杀菌作用的小分子化合物,对 Xanthomonas axonopodis pv. citri (Xac)、Xanthomonas oryzae pv. oryzae (Xoo)和 Pseudomonas syringae pv. actinidiae (Psa) 具有抑制作用。ROS inducer 1 诱 Xanthomonas 细胞内 ROS 的产生可用于研究农作物细菌感染。
T19246 Codon readthrough inducer 1

Others Others
Codon readthrough inducer 1 contains pyrimidine bases and shows good readthrough activity.
T30102 Apoptosis inducer 5d

Others Others
Apoptosis inducer 5D is a new type of inducer that induces cell death by activating the apoptosis of cancer cells.
T63232 Apoptosis inducer 6

Others Others
Apoptosis inducer 6 是一种抗癌剂,具有广谱抗癌活性,能够诱导细胞凋亡 (apoptosis) 触发细胞死亡。
T79252 Apoptosis inducer 13

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
Apoptosisinducer 13(Compound Ru4)能够诱导癌细胞进入凋亡并抑制其迁移与侵袭。该化合物能促进NADH向NAD+的转化,同时提升细胞内ROS的水平。
T79517 ROS inducer 2

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
ROS inducer 2 (Compound I16) 是一种经体外测试显示具有良好活性的活性氧诱导剂,其EC50值为3.43 μg/mL。在体内实验中,该化合物对Xanthomonas axonopodis pv. citri表现出优异的生物活性,可以作为研究难治性植物细菌性疾病的杀菌剂。
T74493 Apoptosis inducer 4

Others Others
Apoptosisinducer 4 (Compound 12b) 是一种具有抗癌活性的细胞凋亡 (apoptosis) 诱导剂。
T74490 Apoptosis inducer 3

Others Others
Apoptosisinducer 3 (Compound 3) 是一种能够选择性诱导细胞凋亡(apoptosis)及其后期过程的化合物,对癌细胞表现出特有的毒性。
T61580 Autophagy inducer 3

Others Others
Autophagy Inducer 3 is a chemical compound that exhibits autophagy-induced activity, specifically inducing robust autophagic cell death in various cancer cells while sparing normal cells. This compound induces lethal autophagy through the formation of distinct autophagic vacuoles, LC3 puncta formation, and upregulation of signature autophagy markers such as Beclin and Atg family proteins [1].
T62399 Apoptosis inducer 10

Others Others
Apoptosis inducer 10 是一种有效的细胞凋亡诱导剂,具有抗增殖活性。Apoptosis inducer 10 利用线粒体依赖性内源性途径,诱导 HeLa 癌细胞凋亡 (apoptosis)。
T63485 Apoptosis inducer 8

Others Others
Apoptosis inducer 8 是一种galectin-1 (gal-1)介导的凋亡 (apoptosis) 诱导剂,也是一种PET 显像剂,能够明显减少 gal-1 蛋白水平,可用于全球主要的肺癌的研究。
T78686 Apoptosis inducer 11

Apoptosis Apoptosis
Apoptosisinducer 11(compound 3u)通过线粒体途径引发细胞凋亡。在非霍奇金淋巴瘤细胞系中,该化合物导致G2/M期停滞和S期显著减少。
T79208 Oct4 inducer-2

Others Others
Oct4 inducer-2, 作为OCT4诱导剂,维持hiPSC形成通过促进内源性OCT4表达,适用于抗衰老研究。
T72403 Ferroptosis inducer-1

Others Others
Ferroptosisinducer-1 是一种铁凋亡 (Ferroptosis) 诱导剂,具有抗肿瘤的潜力。
T82952 ATF3 inducer 1

Others Others
ATF3 inducer 1, 作为一种高效ATF3诱导剂,能显著提高ATF3蛋白及其mRNA的表达水平,并在小鼠模型中展现出对MetS的抗性活性。
T63744 Autophagy inducer 4

Others Others
Autophagy inducer 4 是基于 Magnolol 的曼尼希碱衍生物,能够用作抗癌剂。Autophagy inducer 4 能够诱导自噬 (autophagy) 进而抑制癌细胞。Autophagy inducer 4 对 T47D 细胞的毒性是 Magnolol 的 76 倍。Autophagy inducer 4 也能够抑制 T47D 和 Hela 癌细胞的迁移。
T79518 ROS inducer 3

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
ROS inducer 3 (Compound I6) 是活性氧诱导剂,体外活性良好,其 EC50 值为 2.86 μg/mL。该化合物在体内展现对 Pseudomonas syringae pv. actinidiae 的卓越生物活性,因此可作为研究难治性植物细菌性疾病的杀菌剂。
T74787 Apoptosis inducer 12

Others Others
Apoptosisinducer 12 (Compound 3z),一种凋亡诱导剂,通过线粒体途径促进细胞凋亡(apoptosis),主要应用于癌症研究。
T60898 HbF inducer-1

Others Others
HbF inducer-1 是一种胎儿血红蛋白诱导剂,具有口服生物活性。
T74225 ROS-ERS inducer 1

Others Others
ROS-ERS inducer 1 是一种基于4,5-二芳基咪唑的Pt(II)-N-杂环卡宾 (Pt(II)-NHC) 复合物,属于 II 型免疫原性细胞死亡(ICD)诱导剂。它能促使内质网应激(ERS)并伴随活性氧(ROS)的生成,进而在HCC细胞中触发损伤相关分子模式(DAMP)的释放。相比Cisplatin,ROS-ERS inducer 1 表现出更高的抗癌效能。
T13554 Arimoclomol maleate

BRX-220

HSP Cytoskeletal Signaling; Metabolism
Arimoclomol maleate (BRX-220) 是一种热休克蛋白 (HSP) 的共诱导剂。它通过增强 Hsp 表达来保护运动神经元,进而通过蛋白酶体-泛素系统直接影响蛋白质聚集和错误折叠装配体的清除
T13553 Arimoclomol

阿瑞洛莫,BRX-220 free base

HSP Cytoskeletal Signaling; Metabolism
Arimoclomol (BRX-220 free base) 是热休克蛋白 (HSP) 的共诱导剂,可用于治疗肌萎缩侧索硬化症的研究。
T60262 Cholera autoinducer 1

Others Others
Cholera autoinducer 1 是霍乱弧菌的自诱导剂。Cholera autoinducer 1 影响秀丽隐杆线虫的趋化性。
T33857 PA Autoinducer

3O-C12 autoinducer,PA-Autoinducer

Others Others
PA Autoinducer is a Pseudomonas aeruginosa autoinducer.
T16900 SMER18

Others Others
SMER18 is a small molecule enhancer of rapamycin which acts as an mTOR-independent autophagy inducer.
T19583 TN1

Others Others
TN1 是一种有效的胎儿型血红蛋白 (HbF) 诱导剂。
T16901 SMIP004

Apoptosis; Others; E1/E2/E3 Enzyme Apoptosis; Others; Ubiquitination
SMIP004 是一种 SKP2 E3 连接酶抑制剂。 SMIP004 是人前列腺癌细胞的癌细胞特异性凋亡诱导剂。
T1743 Aprepitant

MK-869,MK-0869,阿瑞匹坦,L-754030,Aprepitant`

HIV Protease; Antibacterial; Antibiotic; Neurokinin receptor GPCR/G Protein; Microbiology/Virology; Neuroscience; Proteases/Proteasome
Aprepitant (Aprepitant`) 是选择性和高亲和力的神经激肽1受体拮抗剂,Kd 值为86 pM。
T21082 2,5-Dihydroxybiphenyl

TFIIH Modulator 12,2,5-二羟基联苯,TFIIH Modulator12

Others Others
2,5-Dihydroxybiphenyl (TFIIH Modulator12) 是一种小分子去稳定诱导剂,可诱导毛发硫营养不良组 A 蛋白的二聚化,从而调节 TFIIH 转录活性。
T4066 FIN56

Ferroptosis Apoptosis
FIN56 是一种铁死亡特异性诱导剂,能结合并激活角鲨烯合酶,可通过诱导 GPX4 降解来诱导铁死亡。
T8762 SW106065

SW-106065

Apoptosis Apoptosis
SW106065 是一种恶性外周神经鞘瘤(MPNST)细胞凋亡诱导剂。 它抑制 sMPNST 和其他 MPNST 模型的 ATP 消耗,EC50 为 1 µM。
T10687 Casein Kinase II Inhibitor IV

Casein Kinase Metabolism; Stem Cells
Casein Kinase II Inhibitor IV 是一种小分子诱导剂,可诱导表皮角质形成细胞分化。
T0538 3-Methylindolin-2-one

3-Methyloxindole,3-Methyl-2-oxindole,3-甲基羟基吲哚

Others; Endogenous Metabolite; AChE Metabolism; Neuroscience; Others
3-Methyloxindole 是一种酚类病毒诱导剂,是一种乙酰胆碱酯酶抑制。
T62827 BCP-T.A

Ferroptosis; GPX Apoptosis; oxidation-reduction
BCP-T.A 是一种铁死亡诱导剂,通过与 GPX4 结合发挥作用。
T2439 O4I1

OCT Membrane transporter/Ion channel
O4I1 是一种Oct3/4诱导剂。
T6149 YH239-EE

Apoptosis; E1/E2/E3 Enzyme Apoptosis; Ubiquitination
YH239-EE 是 YH239 的乙酯,是 p53-MDM2 拮抗剂和凋亡诱导剂。
TP1170L Flagelin 22 acetate

Flagelin 22 acetate(304642-91-9 free base)

Others Others
Flagelin 22 acetate 是细菌鞭毛蛋白的一部分,是在植物和藻类中一种有效的诱导剂。
T2055 WS3

EGFR; IκB/IKK Angiogenesis; JAK/STAT signaling; NF-κB; Tyrosine Kinase/Adaptors
WS3 是一种可促进鼠和人原代胰岛的胰腺 β 细胞增殖的增殖分子。它可用于研究 I 型糖尿病。
T8331 NUN82647

CU-242

Others Others
NUN82647 (CU-242) 是 G2 期细胞周期抑制剂和凋亡诱导剂。
T20436 DHQ

2,3-dihydroxy-quinoxalin,2,3-二羟基喹喔啉

ATPase Membrane transporter/Ion channel
DHQ (2,3-dihydroxy-quinoxalin) 是单纯疱疹病毒胸苷激酶的 ATPase 活性诱导剂。
T22661 CHM-1

Apoptosis; Others; Microtubule Associated Apoptosis; Cytoskeletal Signaling; Others
CHM-1 是细胞凋亡的诱导剂,通过激活 Cdc2 激酶活性在人肝细胞癌中显示出有效的抗肿瘤能力。 CHM-1 在体外和体内抑制微管蛋白聚合。
T19783 Dehydroabiethylamine

NSC-2955,NSC 2955,Dehydroabietylamine,NSC2955,Leelamine free base,Leelamine,脱氢松香胺

P450; PDK Metabolism; PI3K/Akt/mTOR signaling
Dehydroabiethylamine (NSC-2955) 是肝脏 CYP2B 活性的诱导剂。 Dehydroabiethylamine 抑制丙酮酸脱氢酶激酶 (PDK) 和细胞内胆固醇转运,具有抗肿瘤活性。
T8468 CIL62

Caspase Apoptosis; Proteases/Proteasome
CIL62 是一种不依赖 caspase-3/7 的细胞死亡诱导剂。CIL62的作用机制是 Necrostatin-1 依赖性细胞死亡。

化合物

Methuosis inducer 1
Cat.No: T7262
Synonym:
Target: Others
BiP inducer X
Cat.No: T30480
Synonym: BIX
Target: Apoptosis
P62-mediated mitophagy inducer
Cat.No: T13809
Synonym: PMI
Target: Mitophagy
Interferon receptor inducer-1
Cat.No: T13736
Synonym:
Target: IFNAR
C/EBPα inducer 1
Cat.No: T8871
Synonym: 4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-
Target: Others
Oct3/4-inducer-1
Cat.No: T3221
Synonym: 2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile,2-(4-[(4-甲氧基苄基)氧基]苯基)乙腈
Target: Others, OCT
EBV lytic cycle inducer-1
Cat.No: T77753
Synonym: Dp44mT
Target: Antifection
ROS inducer 1
Cat.No: T77574
Synonym:
Target: ROS, Antibiotic
Codon readthrough inducer 1
Cat.No: T19246
Synonym:
Target: Others
Apoptosis inducer 5d
Cat.No: T30102
Synonym:
Target: Others
Apoptosis inducer 6
Cat.No: T63232
Synonym:
Target: Others
Apoptosis inducer 13
Cat.No: T79252
Synonym:
Target: Reactive Oxygen Species
ROS inducer 2
Cat.No: T79517
Synonym:
Target: Reactive Oxygen Species
Apoptosis inducer 4
Cat.No: T74493
Synonym:
Target: Others
Apoptosis inducer 3
Cat.No: T74490
Synonym:
Target: Others
Autophagy inducer 3
Cat.No: T61580
Synonym:
Target: Others
Apoptosis inducer 10
Cat.No: T62399
Synonym:
Target: Others
Apoptosis inducer 8
Cat.No: T63485
Synonym:
Target: Others
Apoptosis inducer 11
Cat.No: T78686
Synonym:
Target: Apoptosis
Oct4 inducer-2
Cat.No: T79208
Synonym:
Target: Others
Ferroptosis inducer-1
Cat.No: T72403
Synonym:
Target: Others
ATF3 inducer 1
Cat.No: T82952
Synonym:
Target: Others
Autophagy inducer 4
Cat.No: T63744
Synonym:
Target: Others
ROS inducer 3
Cat.No: T79518
Synonym:
Target: Reactive Oxygen Species
Apoptosis inducer 12
Cat.No: T74787
Synonym:
Target: Others
HbF inducer-1
Cat.No: T60898
Synonym:
Target: Others
ROS-ERS inducer 1
Cat.No: T74225
Synonym:
Target: Others
Arimoclomol maleate
Cat.No: T13554
Synonym: BRX-220
Target: HSP
Arimoclomol
Cat.No: T13553
Synonym: 阿瑞洛莫,BRX-220 free base
Target: HSP
Cholera autoinducer 1
Cat.No: T60262
Synonym:
Target: Others
PA Autoinducer
Cat.No: T33857
Synonym: 3O-C12 autoinducer,PA-Autoinducer
Target: Others
SMER18
Cat.No: T16900
Synonym:
Target: Others
TN1
Cat.No: T19583
Synonym:
Target: Others
SMIP004
Cat.No: T16901
Synonym:
Target: Apoptosis, Others, E1/E2/E3 Enzyme
Aprepitant
Cat.No: T1743
Synonym: MK-869,MK-0869,阿瑞匹坦,L-754030,Aprepitant`
Target: HIV Protease, Antibacterial, Antibiotic, Neurokinin receptor
2,5-Dihydroxybiphenyl
Cat.No: T21082
Synonym: TFIIH Modulator 12,2,5-二羟基联苯,TFIIH Modulator12
Target: Others
FIN56
Cat.No: T4066
Synonym:
Target: Ferroptosis
SW106065
Cat.No: T8762
Synonym: SW-106065
Target: Apoptosis
Casein Kinase II Inhibitor IV
Cat.No: T10687
Synonym:
Target: Casein Kinase
3-Methylindolin-2-one
Cat.No: T0538
Synonym: 3-Methyloxindole,3-Methyl-2-oxindole,3-甲基羟基吲哚
Target: Others, Endogenous Metabolite, AChE
BCP-T.A
Cat.No: T62827
Synonym:
Target: Ferroptosis, GPX
O4I1
Cat.No: T2439
Synonym:
Target: OCT
YH239-EE
Cat.No: T6149
Synonym:
Target: Apoptosis, E1/E2/E3 Enzyme
Flagelin 22 acetate
Cat.No: TP1170L
Synonym: Flagelin 22 acetate(304642-91-9 free base)
Target: Others
WS3
Cat.No: T2055
Synonym:
Target: EGFR, IκB/IKK
NUN82647
Cat.No: T8331
Synonym: CU-242
Target: Others
DHQ
Cat.No: T20436
Synonym: 2,3-dihydroxy-quinoxalin,2,3-二羟基喹喔啉
Target: ATPase
CHM-1
Cat.No: T22661
Synonym:
Target: Apoptosis, Others, Microtubule Associated
Dehydroabiethylamine
Cat.No: T19783
Synonym: NSC-2955,NSC 2955,Dehydroabietylamine,NSC2955,Leelamine free base,Leelamine,脱氢松香胺
Target: P450, PDK
CIL62
Cat.No: T8468
Synonym:
Target: Caspase
Cat. No. Product Name Target Signaling Pathways
T72509 Apoptosis inducer 5

Others Others
Apoptosisinducer 5 是一种木脂素对映异构体,存在于Crataegus pinnatifida 中。Apoptosisinducer 5 通过 Hep3B 细胞中的凋亡和自噬表现出细胞毒性作用。
T2O2707 D-(+)-Fucose

Others Others
D-(+)-Fucose 是一种 l-阿拉伯糖的非代谢类似物,也是 β-甲基半乳糖苷透皮酶诱导剂。它能够抑制 l-阿拉伯糖操纵子的诱导,阻断大肠杆菌 B/r 在矿物盐培养基上加 l-阿拉伯糖的生长。
TMA1403 Cyclo(Ile-Ala)

Others Others
Cyclo(Ile-Ala) 是存在于海洋放线菌11014 I.中的天然产物,是细胞周期抑制剂。
T5132 9-dihydro-13-acetylbaccatin III

13-乙酰基-9-羟基巴卡丁 III,13-Acetyl-9-dihydrobaccatin III,9-DHAB III

Apoptosis Apoptosis
9-dihydro-13-acetylbaccatin III (9-DHAB III) 是一种制备紫杉醇类似物的中间体。
T5546 Helicin

绣线菊苷,Helecin

Others Others
Helicin 是一种发现于在蔷薇科中的syrB诱导剂。其中BglY 酶可水解 Helicin。
T5080 Spermidine trihydrochloride

Spermidine hydrochloride,4-Azaoctamethylenediamine trihydrochloride,三盐酸亚精胺,亚精胺盐酸盐

NMDAR; Autophagy Autophagy; Neuroscience
Spermidine trihydrochloride (4-Azaoctamethylenediamine trihydrochloride) 能够维持细胞膜稳定性,提高抗氧化酶特性,改善光系统 II (PSII) 以及相关基因表达,也能够显著抑制 H2O2和 O2.-含量。
TN6705 Graveoline

1-甲基-2- [3' ,4' - (亚甲二氧基)苯基] -4-喹诺酮,2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one,Foliosine

Autophagy Autophagy
Graveoline (2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one) 是皮肤黑色素瘤癌细胞的凋亡和自噬诱导剂。
T5293 Maltotriose

D-Maltotriose,麦芽三糖,Amylotriose

Others; Endogenous Metabolite Metabolism; Others
Maltotriose 是一种大肠杆菌麦芽糖调节剂的诱导剂,是酿造中含量第二高的糖。它能够诱导β-半乳糖苷酶合成。
T41335 cis-Vaccenic acid

cis-11-Octadecenoic acid,Asclepic acid,(Z)-octadec-11-enoic acid

Antiviral Immunology/Inflammation
cis-Vaccenic acid (Asclepic acid) 是来自 Rhodopseudomonas capsulate 的抗病毒提取物,是 Rhodopseudomonas capsulate 的主要活性成分,cis-Vaccenic acid 可用作潜在的胎儿血红蛋白诱导剂。
TN2264 Terpinen-4-ol

Terpinine-4-ol,4-萜烯醇,4-Carvomenthenol

Others; Endogenous Metabolite Metabolism; Others
Terpinen-4-ol 是天然单萜,是茶树油的主要生物活性成分。它通过激活的人单核细胞抑制炎症介质的产生,能显著增强多种化疗和生物制剂的疗效。
T2799 (20S)-Protopanaxadiol

20-Epiprotopanaxadiol,20(S)-APPD,20 (S)-原人参二醇,原人参二醇

Apoptosis; Reactive Oxygen Species; P-gp Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB
(20S)-Protopanaxadiol (20-Epiprotopanaxadiol) 是人参皂甙的代谢产物,是一种凋亡诱导剂,抑制Akt 活性并诱导多种肿瘤细胞凋亡。
T4519 Alisol A

Alisol-A,泽泻醇 A

Autophagy Autophagy
Alisol A (Alisol-A) 是泽泻中的一种三萜类天然产物,可能是一种自噬诱导剂,具有抗癌活性。
T5701 OPHIOPOGONIN D

麦冬皂苷 D,麦冬皂苷D

RAAS; Calcium Channel; NF-κB; PPAR DNA Damage/DNA Repair; Endocrinology/Hormones; Membrane transporter/Ion channel; Metabolism; NF-κB
Ophiopogonin D 是从麦冬的块茎中分离的一种天然产物,是罕见的天然存在的 C29甾体糖苷。它是一种 CYP2J3 诱导剂,用于炎症和心血管疾病的相关研究。
T5515 Hemin

氯化血红素,Hemin chloride

Mitophagy; Ferroptosis; Autophagy Apoptosis; Autophagy
Hemin (Hemin chloride) 是一种含有氯的含铁卟啉,一种血红素加氧酶 (HO)-1 诱导剂。Hemin 对卟啉病具有治疗活性,可以减少患者的血红素缺乏,从而通过生物化学反馈抑制 δ-氨基乙酰丙酸合成酶的活性。
TN2082 Pinostrobin

Beta Amyloid; IL Receptor; Serine/threonin kinase; TNF Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation; Metabolism; Neuroscience
Pinostrobin 是一种 PCSK9抑制剂,可抑制 PCSK9 的催化活性。它是能够在多种植物中发现的黄酮类化合物,并具有抗氧化,抗炎,抗癌和神经保护作用。它是有前景的胆固醇调节和脂质管理剂。
TN2272 Tigloylgomisin H

Nrf2 Immunology/Inflammation
Tigloylgomisin H 是分离自S. chinensis 果实中的木酚素。Tigloylgomisin H 能诱导小鼠肝癌细胞 Hepa1c1c7 中醌还原酶活性。Tigloylgomisin H 是单功能诱导剂,通过 Nrf2-ARE 途径特异性上调 II 期解毒酶 NQO1。Tigloylgomisin H 是潜在的肝癌预防剂。
T5429 Theaflavin 3,3'-digallate

茶黄素-3,3'-双没食子酸,8-Gingerol,TFDG

Virus Protease; Antioxidant; HIV Protease; HSV Microbiology/Virology; oxidation-reduction; Proteases/Proteasome
Theaflavin 3,3'-digallate (8-Gingerol) 是一种寨卡病毒蛋白酶抑制剂,IC50为 2.3 μM。它直接与 ZIKVpro 结合并抑制 ZIKV 复制,可抑制 gp41 和 NS2B-3 蛋白酶的活性,并具有抗 HSV 和 HIV-1病毒活性。它是红茶中的主要多酚,有抗肿瘤作用。
TN3609 Catalposide

Hydroxybenzoyl catalpol

ERK; IL Receptor; TNF; NOS; NF-κB; NO Synthase; PPAR; Autophagy Apoptosis; Autophagy; DNA Damage/DNA Repair; Immunology/Inflammation; MAPK; Metabolism; NF-κB
Catalposide 是一种有效的 (HO)-1 诱导剂,从 Catalpa ovate G. Don(紫葳科)中分离出来。 Catalposide 具有抗氧化、抗细胞凋亡、抗微生物、抗肿瘤和抗炎特性。
T60789 L-Cystine dihydrochloride

Nrf2 Immunology/Inflammation
L-Cystine dihydrochloride 是 Nrf2 诱导剂,具有美白和抗黑斑效果。L-Cystine dihydrochloride 在细胞中有胞保护作用,常添加在各种真菌培养基中当做碳源。
TQ0302 Thapsigargin

毒胡萝卜素

Apoptosis; SARS-CoV; Calcium Channel Apoptosis; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
Thapsigargin 属于天然产物,是一种肌/内质网 Ca2+ ATP 酶 (SERCA) 的抑制剂,也是一种内质网应激诱导剂。Thapsigargin 通过阻断细胞将钙泵入肌浆和内质网的能力来提高胞浆钙浓度。
T15027 Cyclopiazonic acid

环匹阿尼酸,环二氮酸

Calcium Channel Membrane transporter/Ion channel; Metabolism
Cyclopiazonic acid 是一种神经毒性次级代谢产物 (SM),源于A. flavus,是一种纳摩尔内质网钙 ATP 酶抑制剂 (Ca2+ATPase; SERCA),是植物细胞死亡的有效诱导剂。
TN5888 Toddaculin

Others Others
Toddaculin 是一种天然香豆素,抑制过度的破骨细胞活性并增强成骨细胞分化和矿化。它可诱导白血病细胞分化和凋亡,具有抗炎活性。
T6S1027 Tussilagone

Others Others
Tussilagone 是Tussilago farfara 的主要活性成分,具有抗炎作用。它抑制盲肠结扎和穿刺导致脓毒症的小鼠的炎症反应,提高其生存率。它改善葡聚糖硫酸钠诱导的小鼠结肠炎的炎症反应。
T4956 Tetrahydroxystilbene-2-O-β-D-glucoside

tetrahydroxyl diphenylethylene-2-o-gluco,何首乌苷,EH-201

Others Others
Tetrahydroxystilbene-2-O-β-D-glucoside (EH-201) 是一种低分子量的促红细胞生成素诱导剂。
TN1245 3-Deoxysappanchalcone

Others; Akt; mTOR Cytoskeletal Signaling; Others; PI3K/Akt/mTOR signaling
3-Deoxysappanchalcone is an effective HO-1 inducer at the translational level.
T29462 5-OH-HxMF

5-OH-HxMF is an inducer of neurite growth in PC12 cells through the camp / PKA / CREB pathway.
T21005 Lupulon

Others Others
Lupulon has a role as an apoptosis inducer, antimicrobial agent, angiogenesis inhibitor, and antineoplastic agent.
TN4127 Gentiside J

Others Others
Gentiside J is a potent inducer of neurite outgrowth on PC12 cells.
T6569L Mimocine

Mimocine

Others Others
Mimosine, a plant amino acid, is known to act as a normoxic inducer of hypoxia-inducible factor (HIF).
T13624 Conophylline

Others Others
Conophylline is a natural alkaloid extracted from a tropical plant Ervatamia microphylla. Conophylline is a differentiation inducer of for pancreatic cells and suppresses HSC and induces apoptosis.
TN6422 Ethyl (E)-ferulate

Ethyl ferulate could be used for therapeutic purposes as a potent inducer of HO-1 for the protection of brain cells against oxidative and neurodegenerative conditions.
T4954L Smilagenin

PYM50028,Cogane,AI3-44895,PYM 50028

Smilagenin is an orally active inducer of nonpeptide neurotrophic factor. It also prevents and reverses neuronal damage induced by MPP+ in mesencephalic neurons, and by MPTP in a mouse model of Parkinson's disease.
TQ0258 Corynoxine B

柯诺辛碱 B,柯诺辛碱B

Autophagy Autophagy
Corynoxine B is a Beclin-1-dependent autophagy inducer. It is an natural alkaloid isolated from Uncaria rhynchophylla (Miq.) Jacks (Gouteng in Chinese).
TN4126 Gentiside B

Others Others
Gentiside B is a potent inducer of neurite outgrowth on PC12 cells, it shows a significant neuritogenic activity at 30 microM against PC12 cells that is comparable to that seen for the best nerve growth factor (NGF) concentration of 40 ng/mL.
T35605 Apoptolidin

Others Others
Apoptolidin is an apoptosis inducer originally isolated from Nocardiopsis bacteria. It inhibits the mitochondrial F1FO ATPase (Ki = 4-5 μM). Apoptolidin selectively kills transformed glial cells without significantly affecting untransformed cells. It also has antibiotic and antifungal actions.
T75508 Bleomycin A5

Others Others
Bleomycin A5 (Pingyangmycin),一种具有口服活性的糖肽类抗生素,既是抗肿瘤剂、细胞凋亡诱导剂,又是细菌代谢产物。
TN4651 Neuchromenin

Others Others
(-)-Neuchromenin is an inducer of neurite outgrowth of PC12 cells at concentration of 2.5-10 ug/ml.
TN3572 Calyxin H

HSP Cytoskeletal Signaling; Metabolism
Calyxin H at 1uM can increase the expression of heat shock factor 1 (HSF1), it has a possible application as a heat shock protein (HSP) inducer.
TQ0112 Tubulysin A

TubA

Microtubule Associated; ADC Cytotoxin Antibody-drug Conjugate/ADC Related; Cytoskeletal Signaling
Tubulysin A is a natural product from myxobacterial. It has many function in vitro assays, including anti-microtubule, anti-mitotic, an apoptosis inducer, anticancer, and anti-angiogenic.
TN5486 Pinobanksin 3-(2-methyl)butyrate

Apoptosis Apoptosis
Pinobanksin 3-(2-methyl)butyrate 是 Pinobanksin 衍生物。pinobanksin 是一种细胞凋亡诱导剂,可诱导 F6细胞凋亡。
TN5222 Vasicinol

6-Hydroxypeganine

Others Others
Vasicinol (6-Hydroxypeganine) 是一种可从Adhatoda vasica (L.), Nees 中分离出来的吡咯喹唑啉生物碱,是蔗糖酶抑制剂,抑制大鼠肠道α-葡萄糖苷酶的蔗糖水解活性,Ki值为183μM。Vasicinol 是一种 HbF 诱导剂,可用研究代谢紊乱和糖尿病。
TN3838 Desmethylrocaglamide

Others Others
Desmethylrocaglamide is a novel inducer of cellular differentiation using HL-60 promyelocytic cells, it may be a drug for the prevention and therapy of cancer. It also has insecticidal activity.
TN3616 Cedrelone

Apoptosis; MMP; Antifection Apoptosis; Microbiology/Virology; Proteases/Proteasome
Cedrelone 是一种柠檬苦素类化合物,是一种吩嗪生物合成样结构域蛋白 (PBLD) 激活剂。Cedrelone 可诱导癌细胞凋亡 (apoptosis)。Cedrelone 是一种非常有效的细胞凋亡诱导剂,它能导致细胞周期停止。Cedrelone 具有杀虫活性,可抑制 P. saucia 的箭毒生长,并可抑制乳草蝽(Oncopeltus fasciatus)的蜕皮。Cedrelone具有抗肿瘤作用,对SMMC-7721、A-549、MCF-7 和 SW480 等癌细胞株具有显著的细胞毒性。
T72965 Inuviscolide

Others Others
Inuviscolide,一种诱导细胞凋亡(apoptosis)的化合物,能够引起人黑素瘤细胞系在G2/M期的停滞,并展现出抗肿瘤和抗炎活性。
TN3057 4-O-Methylbutein

Autophagy Autophagy
4-O-Methylbutein (2',3,4'-trihydroxy-4-methoxychalcone) may have anti-inflammation activity, it is a potent heme oxygenase-1 (HO-1) inducer, the upregulation of HO-1 has proven to be a useful tool for fighting inflammation.
TN3806 Dehydroglyasperin C

ERK; IκB/IKK; p38 MAPK; TNF; NF-κB; Akt; COX; PI3K; NADPH; DNA/RNA Synthesis; Nrf2; JNK; Autophagy Apoptosis; Autophagy; Cell Cycle/Checkpoint; Cytoskeletal Signaling; DNA Damage/DNA Repair; Immunology/Inflammation; MAPK; Metabolism; Neuroscience; NF-κB; PI3K/Akt/mTOR signaling
Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemopreventive, and neuroprotective activities, it has protective effects against chronic diseases
T14121 Actinonin

(-)-Actinonin

Aminopeptidase Metabolism
Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces and a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM, it also is an apoptosis inducer. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase, it also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin has antiproliferative and antitumor activities[1][2][3][4][5].
T32162 Ingenol disoxate

LEO-43204,LEO43204,LEO 43204

Others Others
Ingenol disoxate, also known as LEO43204, is a Novel 4-Isoxazolecarboxylate Ester of Ingenol with Improved Properties for Treatment of Actinic Keratosis and Other Non-Melanoma Skin Cancers. Ingenol is a natural product found in the sap of the plant Euphor
T11712 Jasplakinolide

Jaspamide,NSC-613009

Microtubule Associated; Antifungal Cytoskeletal Signaling; Microbiology/Virology
Jasplakinolide(Jaspamide) 是一种来自海洋海绵 (marine sponge) 的天然环状肽,是一种有效的肌动蛋白聚合反应 (actin polymerization) 诱导剂。Jasplakinolide 具有抗真菌和抗肿瘤活性,可以稳定先前存在的肌动蛋白丝。Jasplakinolide 与鬼笔环肽竞争性结合 F-肌动蛋白,对 F-肌动蛋白的 Kd 值为 15 nM。
TN6501 Isololiolide

Isololiolide has phytotoxicity, it inhibited seedling growth of cress and barnyard grass. It also showed in vitro activity against both trypomastigote and intracellular amastigotes of Trypanosoma cruzi, with IC50 values of 32 μM and 40 μM, respectively. I
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天然产物

Apoptosis inducer 5
Cat.No: T72509
Synonym:
Target: Others
D-(+)-Fucose
Cat.No: T2O2707
Synonym:
Target: Others
Cyclo(Ile-Ala)
Cat.No: TMA1403
Synonym:
Target: Others
9-dihydro-13-acetylbaccatin III
Cat.No: T5132
Synonym: 13-乙酰基-9-羟基巴卡丁 III,13-Acetyl-9-dihydrobaccatin III,9-DHAB III
Target: Apoptosis
Helicin
Cat.No: T5546
Synonym: 绣线菊苷,Helecin
Target: Others
Spermidine trihydrochloride
Cat.No: T5080
Synonym: Spermidine hydrochloride,4-Azaoctamethylenediamine trihydrochloride,三盐酸亚精胺,亚精胺盐酸盐
Target: NMDAR, Autophagy
Graveoline
Cat.No: TN6705
Synonym: 1-甲基-2- [3' ,4' - (亚甲二氧基)苯基] -4-喹诺酮,2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one,Foliosine
Target: Autophagy
Maltotriose
Cat.No: T5293
Synonym: D-Maltotriose,麦芽三糖,Amylotriose
Target: Others, Endogenous Metabolite
cis-Vaccenic acid
Cat.No: T41335
Synonym: cis-11-Octadecenoic acid,Asclepic acid,(Z)-octadec-11-enoic acid
Target: Antiviral
Terpinen-4-ol
Cat.No: TN2264
Synonym: Terpinine-4-ol,4-萜烯醇,4-Carvomenthenol
Target: Others, Endogenous Metabolite
(20S)-Protopanaxadiol
Cat.No: T2799
Synonym: 20-Epiprotopanaxadiol,20(S)-APPD,20 (S)-原人参二醇,原人参二醇
Target: Apoptosis, Reactive Oxygen Species, P-gp
Alisol A
Cat.No: T4519
Synonym: Alisol-A,泽泻醇 A
Target: Autophagy
OPHIOPOGONIN D
Cat.No: T5701
Synonym: 麦冬皂苷 D,麦冬皂苷D
Target: RAAS, Calcium Channel, NF-κB, PPAR
Hemin
Cat.No: T5515
Synonym: 氯化血红素,Hemin chloride
Target: Mitophagy, Ferroptosis, Autophagy
Pinostrobin
Cat.No: TN2082
Synonym:
Target: Beta Amyloid, IL Receptor, Serine/threonin kinase, TNF
Tigloylgomisin H
Cat.No: TN2272
Synonym:
Target: Nrf2
Theaflavin 3,3'-digallate
Cat.No: T5429
Synonym: 茶黄素-3,3'-双没食子酸,8-Gingerol,TFDG
Target: Virus Protease, Antioxidant, HIV Protease, HSV
Catalposide
Cat.No: TN3609
Synonym: Hydroxybenzoyl catalpol
Target: ERK, IL Receptor, TNF, NOS, NF-κB, NO Synthase, PPAR, Autophagy
L-Cystine dihydrochloride
Cat.No: T60789
Synonym:
Target: Nrf2
Thapsigargin
Cat.No: TQ0302
Synonym: 毒胡萝卜素
Target: Apoptosis, SARS-CoV, Calcium Channel
Cyclopiazonic acid
Cat.No: T15027
Synonym: 环匹阿尼酸,环二氮酸
Target: Calcium Channel
Toddaculin
Cat.No: TN5888
Synonym:
Target: Others
Tussilagone
Cat.No: T6S1027
Synonym:
Target: Others
Tetrahydroxystilbene-2-O-β-D-glucoside
Cat.No: T4956
Synonym: tetrahydroxyl diphenylethylene-2-o-gluco,何首乌苷,EH-201
Target: Others
3-Deoxysappanchalcone
Cat.No: TN1245
Synonym:
Target: Others, Akt, mTOR
5-OH-HxMF
Cat.No: T29462
Synonym:
Target:
Lupulon
Cat.No: T21005
Synonym:
Target: Others
Gentiside J
Cat.No: TN4127
Synonym:
Target: Others
Mimocine
Cat.No: T6569L
Synonym: Mimocine
Target: Others
Conophylline
Cat.No: T13624
Synonym:
Target: Others
Ethyl (E)-ferulate
Cat.No: TN6422
Synonym:
Target:
Smilagenin
Cat.No: T4954L
Synonym: PYM50028,Cogane,AI3-44895,PYM 50028
Target:
Corynoxine B
Cat.No: TQ0258
Synonym: 柯诺辛碱 B,柯诺辛碱B
Target: Autophagy
Gentiside B
Cat.No: TN4126
Synonym:
Target: Others
Apoptolidin
Cat.No: T35605
Synonym:
Target: Others
Bleomycin A5
Cat.No: T75508
Synonym:
Target: Others
Neuchromenin
Cat.No: TN4651
Synonym:
Target: Others
Calyxin H
Cat.No: TN3572
Synonym:
Target: HSP
Tubulysin A
Cat.No: TQ0112
Synonym: TubA
Target: Microtubule Associated, ADC Cytotoxin
Pinobanksin 3-(2-methyl)butyrate
Cat.No: TN5486
Synonym:
Target: Apoptosis
Vasicinol
Cat.No: TN5222
Synonym: 6-Hydroxypeganine
Target: Others
Desmethylrocaglamide
Cat.No: TN3838
Synonym:
Target: Others
Cedrelone
Cat.No: TN3616
Synonym:
Target: Apoptosis, MMP, Antifection
Inuviscolide
Cat.No: T72965
Synonym:
Target: Others
4-O-Methylbutein
Cat.No: TN3057
Synonym:
Target: Autophagy
Dehydroglyasperin C
Cat.No: TN3806
Synonym:
Target: ERK, IκB/IKK, p38 MAPK, TNF, NF-κB, Akt, COX, PI3K, NADPH, DNA/RNA Synthesis, Nrf2, JNK, Autophagy
Actinonin
Cat.No: T14121
Synonym: (-)-Actinonin
Target: Aminopeptidase
Ingenol disoxate
Cat.No: T32162
Synonym: LEO-43204,LEO43204,LEO 43204
Target: Others
Jasplakinolide
Cat.No: T11712
Synonym: Jaspamide,NSC-613009
Target: Microtubule Associated, Antifungal
Isololiolide
Cat.No: TN6501
Synonym:
Target:
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Cat. No. Product Name Species Expression System
TMPH-01703 CDC25C Protein, Human, Recombinant (His)

Dual specificity phosphatase Cdc25C,M-phase inducer...

Human E. coli
Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity. CDC25C Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 57.4 kDa and the accession number is P30307.
TMPK-01203 TNFRSF19 Protein, Human, Recombinant (hFc)

AW123854,TRADE,TAJ α,AL023044,TAJ-α,Taj,TAJ alpha,Toxicity a...

Human HEK293 Cells
A novel susceptibility gene TNFRSF19, which encodes an orphan member of the TNF receptor superfamily known to be associated with nasopharyngeal carcinoma (NPC) and lung cancer risk. TNFRSF19, a susceptibility gene for nasopharyngeal carcinoma and other cancers, functions as a potent inhibitor of the TGFβ signaling pathway. TNFRSF19 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 42.22 kDa and the accession number is Q9NS6...
TMPK-01204 TNFRSF19 Protein, Human, Recombinant (His)

Taj,TAJ-α,Toxicity and JNK inducer,TAJ-alpha,TRADE,...

Human HEK293 Cells
A novel susceptibility gene TNFRSF19, which encodes an orphan member of the TNF receptor superfamily known to be associated with nasopharyngeal carcinoma (NPC) and lung cancer risk. TNFRSF19, a susceptibility gene for nasopharyngeal carcinoma and other cancers, functions as a potent inhibitor of the TGFβ signaling pathway. TNFRSF19 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 16.55 kDa and the accession number is Q9NS6...
TMPJ-00658 CYR61/CCN1 Protein, Human, Recombinant (hFc)

Cysteine-rich angiogenic inducer 61,IGFBP10,Insulin...

Human HEK293 Cells
Protein CYR61, also known as CCN family member 1, Cysteine-rich angiogenic inducer 61,Insulin-like growth factor-binding protein 10 , GIG1, CYR61, CCN1 and IGFBP10, belongs to the CCN family, CYR61 is a secreted protein and contains one CTCK (C-terminal cystine knot-like) domain,one IGFBP N-terminal domain,one TSP type-1 domain and one VWFC domain. CYR61 promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. CYR61 plays important roles in inflammation and tissue repair. CYR61 ...
TMPH-00998 CD147 Protein, Human, Recombinant (aa 138-323, hFc)

HAb18G,BSG,Basigin,CD147,EMMPRIN,Extracellular matrix metall...

Human HEK293 Cells
CD147 Protein, Human, Recombinant (aa 138-323, hFc) is expressed in HEK293.
TMPH-01358 FXYD3 Protein, Human, Recombinant (His & SUMO)

Phospholemman-like,Chloride conductance inducer pro...

Human E. coli
FXYD3 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 20.5 kDa and the accession number is Q14802.
TMPJ-00160 EMMPRIN/CD147 Protein, Human, Recombinant (His)

5F7,TCSF,OK Blood Group Antigen,Tumor Cell-Derived Collagena...

Human HEK293 Cells
Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen β-chain. EMMPRIN is a transmembrane glycoprotein with different forms, resulting from different modes of glycosylation and N-terminal sequence variants. EMMPRIN can be expressed in breast cancer, oral squamous cell carcinoma, glioma, lymphoma, lung, bladder, and melanoma carcinomas cells. EMMPRIN promotes invasion,...
TMPH-02848 CYR61/CCN1 Protein, Mouse, Recombinant (His)

CCN1,IGFBP-10,CCN family member 1,Protein GIG1,Cysteine-rich...

Mouse E. coli
CYR61/CCN1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 42.6 kDa and the accession number is P18406.
TMPH-01068 CYR61/CCN1 Protein, Human, Recombinant (His & SUMO)

IBP-10,GIG1,IGFBP-10,Insulin-like growth factor-binding prot...

Human E. coli
CYR61/CCN1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 55.4 kDa and the accession number is O00622.
TMPH-00644 Lactose operon repressor Protein, E. coli, Recombinant (His & SUMO)

Lactose operon repressor,lacI

E. coli E. coli
Repressor of the lactose operon. Binds allolactose as an inducer.
TMPK-00727 TNFSF12/TWEAK Protein, Human, Recombinant (hFc)

TWEAK,APO3L,APO3 ligand,MGC129581,UNQ181/PRO207,DR3LG

Human HEK293 Cells
Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is a well known multifunctional cytokine extensively distributed in cell types and tissues. Accumulating evidence has shown that TWEAK binding to the receptor factor-inducible 14 (Fn14) participates in diverse pathologic processes including cell proliferation and death, angiogenesis, carcinogenesis and inflammation.
TMPK-01334 EMMPRIN/CD147 Protein, Canine, Recombinant (His)

Basigin,BSG,M6,OK,5F7,TCSF,CD147

Canine HEK293 Cells
CD147, also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulation of extracellular matrix (ECM) remodeling during physiological and pathological processes including wound healing, inflammatory diseases, and cancer. CD147 is a diagnostic and therapeutic target in cancer and inflammatory diseases, either directly or indirectly, by targeting CD147 partners.
TMPH-00266 Galectin-1/LGALS1 Protein, Bovine, Recombinant (His & SUMO)

Galectin-1,S-Lac lectin 1,14 kDa lectin,LGALS1,Beta-galactos...

Bovine E. coli
Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Galectin-1/LGALS1 Protein, Bovine, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 30.6 kDa and the accession number is P11116.
TMPY-00641 LEC/CCL16 Protein, Human, Recombinant (His)

SCYL4,HCC-4,ILINCK,LMC,SCYA16,NCC-4,CKb12,Mtn-1,LCC-1,LEC,ch...

Human E. coli
CCL16, a chemokine poorly characterized at the functional level. Human CCL16 is a member of the CC family, and its gene maps to human chromosome 17q. In the mouse, only a pseudogene has been identified to date. CCL16 is a functional ligand for CCR1, CCR2, CCR5, and CCR8. Recombinant CCL16 demonstrated chemotactic activity on human monocytes and lymphocytes. Based on the ability of human chemokines to exert activity on and bind to murine receptors, the TSA mouse adenocarcinoma cell line was trans...
TMPJ-00216 IL-12B Protein, Human, Recombinant

Interleukin-12 subunit beta,IL-12B,CLMF p40,NKSF2,Interleuki...

Human HEK293 Cells
Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. IL-12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor encoded by IL12B and a 35 kD subunit encoded by IL12A. IL12 is expressed by activated macrophages that serve as an essential inducer of Th1 cells develop...
TMPY-02223 GSTM2 Protein, Human, Recombinant (His)

GSTM2-2,GTHMUS,glutathione S-transferase mu 2 (muscle),GSTM,...

Human E. coli
Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2, and GSTM2, is a cytoplasm protein that belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains one GST C-terminal domain and one GST N-terminal domain. The glutathione S-transferases (GSTs) are a multigene family of enzymes largely involved in the detoxification of chemicals. Eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, si...
TMPY-02757 TWEAKR/TNFRSF12A Protein, Human, Recombinant (hFc)

FN14,CD266,TWEAKR,tumor necrosis factor receptor superfamily...

Human HEK293 Cells
Fn14 (tumor necrosis factor receptor superfamily, member 12A), also known as TNFRSF12A, is the receptor for TNFSF12/TWEAK. Fn14 shares 82% amino acid identity with the mouse sequence. It contains a signal peptide, an extracellular domain, a membrane-anchoring domain, and a cytoplasmic domain. In response to FGF1, calf serum, or phorbol ester stimulation of human quiescent fibroblasts in vitro, the level of Fn14 is increased. A 1.2-kb FN14 transcript was expressed at high levels in heart, placent...
TMPY-05353 CCL26 Protein, Human, Recombinant

MIP-4alpha,SCYA26,MIP-4a,chemokine (C-C motif) ligand 26,IMA...

Human Baculovirus Insect Cells
The eotaxin subfamily of CC chemokines consists of eotaxin-1/CCL11, eotaxin-2/CCL24 and eotaxin-3/CCL26. All eotaxins induce the trafficking of eosinophils to the sites of inflammation via CC chemokine receptor 3 (CCR3), which is also expressed by several different cell types, including basophils, dendritic cells, smooth muscle cells, epithelial cells and fibroblasts. The sequence similarity between the three eotaxins is limited (<4%), but their functional properties are very similar. Eotaxin-1 ...
TMPJ-01312 TWEAKR/TNFRSF12A Protein, Mouse, Recombinant (hFc)

Fibroblast growth factor-regulated protein 2,TNFRSF12,Tumor ...

Mouse HEK293 Cells
Tumor necrosis factor receptor superfamily member 12A(Tnfrsf12a) is a single-pass type I membrane protein and contains 1 TNFR-Cys repeat. It is weak inducer of apoptosis in some cell types.It promotes angiogenesis and it is the proliferation of endothelial cells. It may modulate cellular adhesion to matrix proteins.TNFR binds specifically to tumor necrosis factor (TNF) and blocks its interaction with cell surface TNF receptors. TNF is a naturally occurring cytokine that is involved in normal inf...

重组蛋白

CDC25C Protein, Human, Recombinant (His)
Cat.No: TMPH-01703
Species: Human
Expression System: E. coli
TNFRSF19 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-01203
Species: Human
Expression System: HEK293 Cells
TNFRSF19 Protein, Human, Recombinant (His)
Cat.No: TMPK-01204
Species: Human
Expression System: HEK293 Cells
CYR61/CCN1 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00658
Species: Human
Expression System: HEK293 Cells
CD147 Protein, Human, Recombinant (aa 138-323, hFc)
Cat.No: TMPH-00998
Species: Human
Expression System: HEK293 Cells
FXYD3 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01358
Species: Human
Expression System: E. coli
EMMPRIN/CD147 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00160
Species: Human
Expression System: HEK293 Cells
CYR61/CCN1 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02848
Species: Mouse
Expression System: E. coli
CYR61/CCN1 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01068
Species: Human
Expression System: E. coli
Lactose operon repressor Protein, E. coli, Recombinant (His & SUMO)
Cat.No: TMPH-00644
Species: E. coli
Expression System: E. coli
TNFSF12/TWEAK Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00727
Species: Human
Expression System: HEK293 Cells
EMMPRIN/CD147 Protein, Canine, Recombinant (His)
Cat.No: TMPK-01334
Species: Canine
Expression System: HEK293 Cells
Galectin-1/LGALS1 Protein, Bovine, Recombinant (His & SUMO)
Cat.No: TMPH-00266
Species: Bovine
Expression System: E. coli
LEC/CCL16 Protein, Human, Recombinant (His)
Cat.No: TMPY-00641
Species: Human
Expression System: E. coli
IL-12B Protein, Human, Recombinant
Cat.No: TMPJ-00216
Species: Human
Expression System: HEK293 Cells
GSTM2 Protein, Human, Recombinant (His)
Cat.No: TMPY-02223
Species: Human
Expression System: E. coli
TWEAKR/TNFRSF12A Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02757
Species: Human
Expression System: HEK293 Cells
CCL26 Protein, Human, Recombinant
Cat.No: TMPY-05353
Species: Human
Expression System: Baculovirus Insect Cells
TWEAKR/TNFRSF12A Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-01312
Species: Mouse
Expression System: HEK293 Cells
Cat. No. Product Name Target Signaling Pathways
TMIJ-0119 Pitavastatin-d4 Sodium Salt

Pitavastatin-d4 Sodium Salt 是 Pitavastatin Sodium Salt 的氘代化合物。Pitavastatin Sodium Salt 的 CAS 号为 574705-92-3。
TMIJ-0051 Hexanoic-d11 acid

Hexanoic-d11 acid 是 Hexanoic acid 的氘代化合物。Hexanoic acid 的 CAS 号为 142-62-1。Caproic acid 是一种无色油状液体,闻起来像奶酪。它是一种天然存在于各种动物脂肪和油中的脂肪酸。它是一种抗性引发诱导剂,可保护番茄植物免受灰霉病菌的侵害。

同位素标记化合物

Pitavastatin-d4 Sodium Salt
Cat.No: TMIJ-0119
Synonym:
Target:
Hexanoic-d11 acid
Cat.No: TMIJ-0051
Synonym:
Target:
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