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EGFR-IN-59 是 EGFR 抑制剂,其IC50值为190 nM,也是一直凋亡 (apoptosis) 诱导剂。EGFR-IN-59 对非小肺癌细胞系 (A549) 和正常肺成纤维细胞 (WI38) 表现出细胞毒性的IC50分别为 8.62 和 52.6 μM。EGFR-IN-59 能够用于研究非小细胞肺癌 (NSCLC)、头颈癌、乳腺癌和结直肠癌等多种癌症。
EGFR-IN-59 是 EGFR 抑制剂,其IC50值为190 nM,也是一直凋亡 (apoptosis) 诱导剂。EGFR-IN-59 对非小肺癌细胞系 (A549) 和正常肺成纤维细胞 (WI38) 表现出细胞毒性的IC50分别为 8.62 和 52.6 μM。EGFR-IN-59 能够用于研究非小细胞肺癌 (NSCLC)、头颈癌、乳腺癌和结直肠癌等多种癌症。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥ 10,600 | 6-8周 | |
50 mg | ¥ 13,800 | 6-8周 | |
100 mg | ¥ 17,500 | 6-8周 |
产品描述 | EGFR-IN-59 is an EGFR inhibitor with an IC50 value of 190 nM and an all-time apoptosis inducer. EGFR-IN-59 exhibited cytotoxicity against a non-small lung cancer cell line (A549) and normal lung fibroblasts (WI38) with IC50s of 8.62 and 52.6 μM, respectively. EGFR-IN-59 EGFR-IN-59 can be used to study a variety of cancers including non-small cell lung cancer (NSCLC), head and neck cancer, breast cancer and colorectal cancer. |
分子量 | 513.57 |
分子式 | C27H23N5O4S |
CAS No. | 2529891-44-7 |
存储 | Shipping with blue ice. |
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