首页 工具
登录
购物车

搜索结果

Search Results for " uptake "
Targets Recommended: Others

309

抑制剂 & 化合物

49

天然产物

1

化合物库

69

重组蛋白

14

同位素标记化合物

如果没找到您满意的产品或者您对产品有其他要求,可以联系我们专业顾问为您提供针对性的合理建议。     QQ咨询       网站留言咨询

提交您的定制咨询

点击图片重新获取验证码
Cat. No. Product Name
L1120 AMPK靶向分子库

80 compounds
80 个靶向AMPK 的分子集合,可用于高通量和高内涵筛选;

化合物库

AMPK靶向分子库
Cat.No: L1120
Compounds: 80
Cat. No. Product Name Target Signaling Pathways
T15130 Dilazep dihydrochloride

Others Others
Dilazep dihydrochloride 是一种腺苷摄取的抑制剂。它可抑制缺血性损伤,血小板聚集和核苷的膜转运。它能够增强腺苷的作用,进而具有脑和冠状血管舒张作用。
T9031 MCU-i4

Others; Mitochondrial Metabolism Metabolism; Others
MCU-i4 阻断IP3依赖的线粒体 Ca2+的摄取,是一种新型 MCU 负调节剂,可结合 MICU1 并损害肌肉细胞生长。
T11064 DMT1 blocker 2

Others Others
DMT1 blocker 2 是一种二价金属转运蛋白 1 的直接抑制剂(IC50:0.83 μM)。它可以阻断体内肠细胞的铁摄取。
T12931 SLC13A5-IN-1

Stearoyl-CoA Desaturase (SCD) Metabolism
SLC13A5-IN-1 是柠檬酸钠协同转运蛋白 (SLC13A5)选择性抑制剂,在 HepG2 细胞中阻断 14C-柠檬酸盐摄取的 IC50 : 0.022 μM。
T15802 LY2183240

FAAH; Autophagy Autophagy; Metabolism; Neuroscience
LY2183240 是大麻素摄取阻滞剂。它是内源性大麻素降解酶脂肪酸酰胺水解酶的有效共价抑制剂。它抑制脂肪酸酰胺水解酶 (FAAH) 活性,IC50 为12.4 nM。它也抑制其他几种脑丝氨酸水解酶,对 MAG 脂肪酶、bh6 和 KIAA1363 的 IC50分别为 5.3、0.09 和 8.2 nM。
T5345 V-9302

Others Others
V-9302 是一种跨膜谷氨酰胺通量的竞争性拮抗剂。它选择性的靶向氨基酸转运体 ASCT2 (SLC1A5),不影响 ASCT1。它能够阻碍 HEK-293 细胞中由 ASCT2 介导的谷氨酰胺摄取 (IC50=9.6 μM)。
T4534 BMS-309403

FABP Metabolism
BMS309403 是有效的、选择性脂肪细胞脂肪酸结合蛋白 aFABP 抑制剂。它可改善载脂蛋白 E 缺乏症小鼠和培养的人内皮细胞的内皮功能。它能够与蛋白质内部的脂肪酸结合口袋相互作用,竞争性地抑制内源性脂肪酸的结合。
T23070 Nisoxetine hydrochloride

Sodium Channel; Monoamine Transporter; Norepinephrine Membrane transporter/Ion channel; Neuroscience
Nisoxetine hydrochloride 是一种去甲肾上腺素转运蛋白 (NET) 抑制剂,Kd 值为 0.76 nM。它是抗抑郁药和局部麻药,可以阻断电压门控性钠通道。
T14327 AS1949490

Phosphatase Metabolism
AS1949490 是选择性SHIP-2抑制剂,其IC50=620 nM。它能够通过上调L6肌管GLUT1基因激活葡萄糖代谢。
T14496 BAMB-4

ITPKA-IN-C14

Others Others
BAMB-4 (ITPKA-IN-C14) 是一种新型的膜渗透型ITPKA 抑制剂,在ADP-Glo 实验中的IC50值为37uM。
T11908 LY2365109 hydrochloride

LY2365109盐酸盐

GlyT Neuroscience
LY2365109 hydrochloride 是高选择性GlyT1抑制剂,抑制过表达 hGlyT1 细胞摄取谷氨酸的IC50值为 15.8 nM.
T39429 AHN 1-055 hydrochloride

3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride

Dopamine Receptor GPCR/G Protein; Neuroscience
AHN 1-055 hydrochloride (3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride) 与多巴胺转运蛋白具有高亲和力,是多巴胺摄取抑制剂,IC50为 71 nM。
T12306 OMDM-5

Cannabinoid Receptor; Endogenous Metabolite; TRP/TRPV Channel GPCR/G Protein; Membrane transporter/Ion channel; Metabolism
OMDM-5 是有效的、选择性的anandamide 细胞摄取抑制剂,Ki 为 4.8 μM。它是VR1 (TRPV1)激动剂,EC50为 75 nM,显示出对大麻素 1 型受体 (CB1) 的弱配体活性 (Ki=4.9 μM)。
T3470 Cis-ACBD

cis-1-aminocyclobutane-1,3-dicarboxylic acid,顺式-氨基二羧酸

Amino Acids and Derivatives Metabolism
Cis-ACBD (cis-1-aminocyclobutane-1,3-dicarboxylic acid) 是一种有效的选择性 N-甲基-D-天冬氨酸受体激动剂。
T8702 SKF-83566

Dopamine Receptor; 5-HT Receptor; AChR GPCR/G Protein; Neuroscience
SKF-83566 是一种具有血脑渗透性和口服活性的 D1 样多巴胺受体拮抗剂和一种较弱的竞争性 5-HT2 受体拮抗剂,Ki 为 11 nM。它是竞争性多巴胺转运蛋白抑制剂,可用于研究帕金森氏症和对尼古丁渴望的缓解的相关研究。
T1233 Oxolinic acid

Emyrenil,Nidantin,NSC 110364,恶喹酸,Dioxacin,Urinox

Dopamine Receptor; DNA/RNA Synthesis; Antibacterial; Antibiotic Cell Cycle/Checkpoint; DNA Damage/DNA Repair; GPCR/G Protein; Microbiology/Virology; Neuroscience
Oxolinic acid (Nidantin) 是一种抗生素,对革兰氏阴性菌和革兰氏阳性菌均有效,可研究急性和慢性尿路感染。它是一种 DNA/RNA 合成抑制剂,也是一种多巴胺摄取抑制剂,能刺激小鼠的活跃过度。
T12302 OMDM-1

(Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide

Endogenous Metabolite Metabolism
OMDM-1 ((Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide) 是有效选择性的代谢稳定 anandamide 细胞摄取抑制剂,Ki=为2.4 μM。
T22276 Bis(maltolato)oxovanadium(IV)

双(麦芽醇)氧钒(IV),BMOV,Bis maltolato oxovanadium,Bis(maltolato)oxovanadium (IV),bis maltolato oxo vanadium,Bis(maltolato)oxovanadium (IV)

Phosphatase; Others Metabolism; Others
Bis(maltolato)oxovanadium(IV) (BMOV) 是一种有效的胰岛素增敏剂,也是一种有效的、竞争性的、可逆的、口服具有活性的光谱蛋白酪氨酸磷酸酶 (PTP) 抑制剂。它抑制HCPTPA,PTP1B,HPTPβ和SHP2的IC50分别为 126 nM,109 nM,26 nM 和 201 nM。
T0031L Ziprasidone hydrochloride

盐酸齐拉西酮,齐拉西酮盐酸盐,CP-88059 hydrochloride,CP-88059,Ziprasidone HCl

Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; Norepinephrine; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Ziprasidone hydrochloride (CP-88059 hydrochloride) 是一种联合 5-HT(5-羟色胺)和多巴胺受体拮抗剂,具有抗精神病活性的强效作用。它也是去甲肾上腺素再摄取抑制剂。
T7153 Vanoxerine dihydrochloride

GBR-12909 dihydrochloride,伐诺司林二盐酸盐,I893 dihydrochloride

Dopamine Receptor GPCR/G Protein; Neuroscience
Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) 是一种竞争性的、有效的、选择性的多巴胺再摄取抑制剂,能够与多巴胺转运体 (DAT) 上的靶点结合。
T36665 Dehydro Nifedipine

BAY-b 4759

Others Others
Dehydro Nifedipine (BAY-b 4759) 是人血浆中硝苯地平的主要代谢物。Dehydro Nifedipine 抑制PC-12细胞葡萄糖摄取,IC50值为130 μM,硝苯地平是一种钙通道阻滞剂,用于治疗高血压和心绞痛。当硝苯地平被细胞色素P450 (CYP)异构体CYP3A4和CYP3A5代谢时形成脱氢硝苯地平。
T0313 Evans blue

Direct Blue 53,C.I. 23860,伊文思蓝

GluR Neuroscience
Evans blue (C.I. 23860) 是一种突触泡谷氨酸吸收的有效抑制剂,同时也是一种AMPA/kainate 受体拮抗剂。
T6437 Cefoperazone

头孢哌酮,Cefob,Medocef

Antibacterial; Antibiotic Microbiology/Virology
Cefoperazone (Medocef) 是一种半合成的头孢菌素,有抗菌活性。
T20953 Lumiflavine

Lumilactoflavin,Lumiflavin,光黃素

Others Others
Lumiflavine (Lumilactoflavin) 是 riboflavine 的结构类似物,能够用于 riboflavin 摄取量的检测。
T67851 rac Desmethyl Citalopram Hydrochloride

5-HT Receptor GPCR/G Protein; Neuroscience
rac Desmethyl Citalopram Hydrochloride 是一种5-羟色胺摄取抑制剂,IC50值为0.013μM。
T22508 3-CPMT

Chlortropbenzyl hydrochloride,3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabicyclo[3.2.1]octane hydrochloride,SL6057,Wy 2149,FC-1

Dopamine Receptor GPCR/G Protein; Neuroscience
3-CPMT (FC-1) 是一种多巴胺摄取抑制剂和一种有效的长效抗组胺剂。
T24540 NO-711ME

NO711ME,NO711 Methyl ester,N-O711 Methyl ester,N O711 Methyl ester

GABA Receptor Membrane transporter/Ion channel; Neuroscience
NO-711ME (N-O711 Methyl ester) 是 NO-711 的前药。它也是一种有效的选择性 GABA 摄取抑制剂。
T1636 Paroxetine hydrochloride

Paroxetine HCl,BRL29060 hydrochloride,FG-7051,BRL29060A,盐酸帕罗西汀

5-HT Receptor; Serotonin Transporter; GRK; AChR; Autophagy Autophagy; GPCR/G Protein; Neuroscience
Paroxetine hydrochloride (Paroxetine HCl) 是一种血清素摄取抑制剂,能抑制 GRK2 活性,IC50值为 14 μM。它可研究抑郁症。
T7591 Coluracetam

MKC-231,考拉西坦

AChR; iGluR Membrane transporter/Ion channel; Neuroscience
Coluracetam (MKC-231) 是一种胆碱吸收增强剂。
T33272 Mefenidil

McN-2378,McN 2378

Others Others
Mefenidil (McN-2378) 是一种选择性脑血管扩张剂,在狗麻醉模型中显示出在不刺激 O2 摄取的情况下增加健康大脑中的 CBF。
T27460 GSK2324

GSK-2324,GSK 2324

FXR Metabolism
GSK2324 是一种有效的 FXR 激动剂,通过减少脂肪酸合成的吸收和选择性减少来控制肝脂质,可用于治疗非酒精性脂肪肝。
T26126 Roxindole

EMD 49980

Dopamine Receptor; 5-HT Receptor GPCR/G Protein; Neuroscience
Roxindole (EMD 49980) 是一种选择性多巴胺自身受体和 5-HT1A 双重激动剂,也是5-羟色胺 (5-HT) 的摄取的抑制剂,具有抗精神病和抗抑郁活性。Roxindole 可用于研究帕金森和神经分裂。
T5327 Amezinium methylsulfate

Amezinium metilsulfate,甲磺美嗪,Amezinium (methylsulfate),Lu-1631

Adrenergic Receptor GPCR/G Protein; Neuroscience
Amezinium methylsulfate (Lu-1631) 具有多种机制,包括刺激 α 和 β-1 受体以及抑制去甲肾上腺素和酪胺的摄取。
T8708 Paroxetine

Serotonin Transporter Neuroscience
Paroxetine 是选择性血清素再摄取抑制剂,是苯基哌啶的衍生物。 它对于甲肾上腺素摄取抑制功能较弱,但比该位点其他SSRIs 更有效。
T68070 Fezolamine

Norepinephrine Neuroscience
Fezolamine 是一种新型可口服的非三环类化合物,具有抗抑郁活性。它在体外阻断[3H]去甲肾上腺素的突触体摄取方面的选择性是摄取[4H]3-羟色胺或[3H]多巴胺的3至2倍。在使用单胺耗尽动物的经典行为测试中,它阻止了利血平和四苯的抑制作用。
T19337 GBR 12783 dihydrochloride

GBR12783 2HCl

Others Others
GBR 12783 dihydrochloride (GBR12783 2HCl) 是一种特异性,有效且选择性的多巴胺摄取抑制剂,可抑制大鼠和小鼠纹状体突触小体对 [3H] 多巴胺 ([3H]dopamine) 的摄取,IC50值分别为 1.8 nM 和 1.2 nM。GBR 12783 dihydrochloride 还可改善大鼠记忆力并增加海马通路乙酰胆碱的释放。
T2227 Hemicholinium 3

半胆碱基-3,Hemicholinium-3,Hemicholine

Others; AChE Neuroscience; Others
Hemicholinium 3 是一种竞争性的、高亲和力的胆碱转运蛋白 (HACU) 抑制剂,Ki=25 nM。它是一种神经肌肉阻滞剂,能够抑制乙酰胆碱 (ACh)的合成和释放。它抑制Epibatidine 诱发的收缩和 [3H] 乙酰胆碱释放,IC50分别为 897 nM 和 693 nM。
T4058 R-IMPP

Others; Serine/threonin kinase Cell Cycle/Checkpoint; Metabolism; Others
R-IMPP 是抗 PCSK9分泌的药物 (IC50=4.8 μM),靶向作用于 80S 核糖体,抑制 PCSK9 蛋白的翻译。
T1430 Betamipron

CS-443,N-Benzoyl-β-alanine,倍他米隆

Antibacterial; Antibiotic Microbiology/Virology
Betamipron (CS-443) 与Panipenem 联用,可抑制Panipenem 摄取进入肾小管,防止肾毒性。
T0482 Sertraline hydrochloride

Sertraline HCl,CP-51974-1 HCl,盐酸舍曲林

5-HT Receptor; Serotonin Transporter GPCR/G Protein; Neuroscience
Sertraline hydrochloride (Sertraline HCl) 是选择性 5- 羟色胺再吸收抑制剂类的抗抑郁剂,可用于多种疾病的研究,如重度抑郁症和强迫症。
T26363L Napitane

A75200,A-75200,A 75200,ABT 200

Adrenergic Receptor GPCR/G Protein; Neuroscience
napitane(A 75200)是一种新型儿茶酚胺摄取抑制剂,对α-肾上腺素能受体具有抑制作用且具有潜在的抗抑郁活性,可用于研究抑郁症。
T25276 Crilvastatin

PMD387,PMD 387,PMD-387

HMG-CoA Reductase Metabolism
Crilvastatin (PMD 387) 是一种新型非竞争性羟甲基戊二酰辅酶 A 还原酶抑制剂,具有降胆固醇活性,可抑制遗传性高胆固醇血症大鼠的胆固醇吸收。
T37015 Iprindole

5-HT Receptor GPCR/G Protein; Neuroscience
Iprindole,一种三环吲哚类抗抑郁化合物,是去甲肾上腺素和5-羟色胺摄取的双重弱抑制剂[1]。
T24793 SIRT6-IN-5

SIRT6 inhibitor5,SIRT6 IN 5,SIRT6 inhibitor-5,SIRT6 inhibitor 5

Sirtuin Chromatin/Epigenetic; DNA Damage/DNA Repair
SIRT6-IN-5(SIRT6 inhibitor 5) 是一种具有有效性和选择性的 SIRT6 抑制剂 ,IC50 值为 34 μM。SIRT6-IN-5 具有免疫抑制和化疗增敏作用,可增加 H3K9 的乙酰化并增加培养细胞中的葡萄糖摄取,减少 T 细胞增殖。
T67893 PTP1B-IN-22

Phosphatase Metabolism
PTP1B-IN-22是一种蛋白酪氨酸磷酸酶1B (PTP1B)抑制剂,可抑制骨骼肌 L6肌管的葡萄糖摄取。
T7070 Nomifensine maleate

Nomifensine (maleate),诺米芬新马来酸盐,(±)-Nomifensine maleat

Dopamine Receptor GPCR/G Protein; Neuroscience
Nomifensine maleate (Nomifensine (maleate)) 是一种多巴胺摄取的选择性抑制剂,可用于成人注意力缺陷障碍的研究。
T21766 ML352

AChE Neuroscience
ML352 是一种具有选择性和高效性的突触前胆碱转运体 (CHT) 抑制剂,抑制非竞争性胆碱摄取。
T0255 Clomipramine hydrochloride

Clomipramine HCl,Anafranil,盐酸氯米帕明

Dopamine Receptor; 5-HT Receptor; Serotonin Transporter; Norepinephrine; GST GPCR/G Protein; Neuroscience; oxidation-reduction
Clomipramine hydrochloride (Anafranil) 是一种5-羟色胺转运体(Ki:0.14 nM)、去甲肾上腺素转运体(Ki:54 nM)和多巴胺转运体(Ki:3 nM)阻断剂。
T0450 Fluoxetine

氟西汀,LY-110140

5-HT Receptor; Serotonin Transporter; MRP; Autophagy Autophagy; GPCR/G Protein; Immunology/Inflammation; Neuroscience
Fluoxetine (LY-110140) 是一种高度特异性的血清素摄取抑制剂,是选择性 5-羟色胺 (5-HT) 再吸收抑制剂。Fluoxetine 具有抗抑郁活性。
T23234 Rimcazole dihydrochloride

Others Others
Rimcazole dihydrochloride 是 Rimcazole 的盐酸盐,是一种σ受体拮抗剂。Rimcazole dihydrochloride 还与多巴胺转运蛋白结合,抑制多巴胺的摄取。

化合物

Dilazep dihydrochloride
Cat.No: T15130
Synonym:
Target: Others
MCU-i4
Cat.No: T9031
Synonym:
Target: Others, Mitochondrial Metabolism
DMT1 blocker 2
Cat.No: T11064
Synonym:
Target: Others
SLC13A5-IN-1
Cat.No: T12931
Synonym:
Target: Stearoyl-CoA Desaturase (SCD)
LY2183240
Cat.No: T15802
Synonym:
Target: FAAH, Autophagy
V-9302
Cat.No: T5345
Synonym:
Target: Others
BMS-309403
Cat.No: T4534
Synonym:
Target: FABP
Nisoxetine hydrochloride
Cat.No: T23070
Synonym:
Target: Sodium Channel, Monoamine Transporter, Norepinephrine
AS1949490
Cat.No: T14327
Synonym:
Target: Phosphatase
BAMB-4
Cat.No: T14496
Synonym: ITPKA-IN-C14
Target: Others
LY2365109 hydrochloride
Cat.No: T11908
Synonym: LY2365109盐酸盐
Target: GlyT
AHN 1-055 hydrochloride
Cat.No: T39429
Synonym: 3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride
Target: Dopamine Receptor
OMDM-5
Cat.No: T12306
Synonym:
Target: Cannabinoid Receptor, Endogenous Metabolite, TRP/TRPV Channel
Cis-ACBD
Cat.No: T3470
Synonym: cis-1-aminocyclobutane-1,3-dicarboxylic acid,顺式-氨基二羧酸
Target: Amino Acids and Derivatives
SKF-83566
Cat.No: T8702
Synonym:
Target: Dopamine Receptor, 5-HT Receptor, AChR
Oxolinic acid
Cat.No: T1233
Synonym: Emyrenil,Nidantin,NSC 110364,恶喹酸,Dioxacin,Urinox
Target: Dopamine Receptor, DNA/RNA Synthesis, Antibacterial, Antibiotic
OMDM-1
Cat.No: T12302
Synonym: (Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide
Target: Endogenous Metabolite
Bis(maltolato)oxovanadium(IV)
Cat.No: T22276
Synonym: 双(麦芽醇)氧钒(IV),BMOV,Bis maltolato oxovanadium,Bis(maltolato)oxovanadium (IV),bis maltolato oxo vanadium,Bis(maltolato)oxovanadium (IV)
Target: Phosphatase, Others
Ziprasidone hydrochloride
Cat.No: T0031L
Synonym: 盐酸齐拉西酮,齐拉西酮盐酸盐,CP-88059 hydrochloride,CP-88059,Ziprasidone HCl
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Norepinephrine, Histamine Receptor
Vanoxerine dihydrochloride
Cat.No: T7153
Synonym: GBR-12909 dihydrochloride,伐诺司林二盐酸盐,I893 dihydrochloride
Target: Dopamine Receptor
Dehydro Nifedipine
Cat.No: T36665
Synonym: BAY-b 4759
Target: Others
Evans blue
Cat.No: T0313
Synonym: Direct Blue 53,C.I. 23860,伊文思蓝
Target: GluR
Cefoperazone
Cat.No: T6437
Synonym: 头孢哌酮,Cefob,Medocef
Target: Antibacterial, Antibiotic
Lumiflavine
Cat.No: T20953
Synonym: Lumilactoflavin,Lumiflavin,光黃素
Target: Others
rac Desmethyl Citalopram Hydrochloride
Cat.No: T67851
Synonym:
Target: 5-HT Receptor
3-CPMT
Cat.No: T22508
Synonym: Chlortropbenzyl hydrochloride,3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabicyclo[3.2.1]octane hydrochloride,SL6057,Wy 2149,FC-1
Target: Dopamine Receptor
NO-711ME
Cat.No: T24540
Synonym: NO711ME,NO711 Methyl ester,N-O711 Methyl ester,N O711 Methyl ester
Target: GABA Receptor
Paroxetine hydrochloride
Cat.No: T1636
Synonym: Paroxetine HCl,BRL29060 hydrochloride,FG-7051,BRL29060A,盐酸帕罗西汀
Target: 5-HT Receptor, Serotonin Transporter, GRK, AChR, Autophagy
Coluracetam
Cat.No: T7591
Synonym: MKC-231,考拉西坦
Target: AChR, iGluR
Mefenidil
Cat.No: T33272
Synonym: McN-2378,McN 2378
Target: Others
GSK2324
Cat.No: T27460
Synonym: GSK-2324,GSK 2324
Target: FXR
Roxindole
Cat.No: T26126
Synonym: EMD 49980
Target: Dopamine Receptor, 5-HT Receptor
Amezinium methylsulfate
Cat.No: T5327
Synonym: Amezinium metilsulfate,甲磺美嗪,Amezinium (methylsulfate),Lu-1631
Target: Adrenergic Receptor
Paroxetine
Cat.No: T8708
Synonym:
Target: Serotonin Transporter
Fezolamine
Cat.No: T68070
Synonym:
Target: Norepinephrine
GBR 12783 dihydrochloride
Cat.No: T19337
Synonym: GBR12783 2HCl
Target: Others
Hemicholinium 3
Cat.No: T2227
Synonym: 半胆碱基-3,Hemicholinium-3,Hemicholine
Target: Others, AChE
R-IMPP
Cat.No: T4058
Synonym:
Target: Others, Serine/threonin kinase
Betamipron
Cat.No: T1430
Synonym: CS-443,N-Benzoyl-β-alanine,倍他米隆
Target: Antibacterial, Antibiotic
Sertraline hydrochloride
Cat.No: T0482
Synonym: Sertraline HCl,CP-51974-1 HCl,盐酸舍曲林
Target: 5-HT Receptor, Serotonin Transporter
Napitane
Cat.No: T26363L
Synonym: A75200,A-75200,A 75200,ABT 200
Target: Adrenergic Receptor
Crilvastatin
Cat.No: T25276
Synonym: PMD387,PMD 387,PMD-387
Target: HMG-CoA Reductase
Iprindole
Cat.No: T37015
Synonym:
Target: 5-HT Receptor
SIRT6-IN-5
Cat.No: T24793
Synonym: SIRT6 inhibitor5,SIRT6 IN 5,SIRT6 inhibitor-5,SIRT6 inhibitor 5
Target: Sirtuin
PTP1B-IN-22
Cat.No: T67893
Synonym:
Target: Phosphatase
Nomifensine maleate
Cat.No: T7070
Synonym: Nomifensine (maleate),诺米芬新马来酸盐,(±)-Nomifensine maleat
Target: Dopamine Receptor
ML352
Cat.No: T21766
Synonym:
Target: AChE
Clomipramine hydrochloride
Cat.No: T0255
Synonym: Clomipramine HCl,Anafranil,盐酸氯米帕明
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine, GST
Fluoxetine
Cat.No: T0450
Synonym: 氟西汀,LY-110140
Target: 5-HT Receptor, Serotonin Transporter, MRP, Autophagy
Rimcazole dihydrochloride
Cat.No: T23234
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
TJS0123 Guvacine ethyl ester

槟榔碱,PT00442-2

Others Others
Guvacine ethyl ester (Arecoline) 是一种生物碱,存在于槟榔中,可用于 GABA 摄取抑制剂的合成。
T5799 Arecaidine hydrochloride

Others Others
Arecaidine hydrochloride 是一种具有高效 GABA 吸收抑制功能的吡啶生物碱。它是 H+偶联的氨基酸转运蛋白 1 (PAT1,SLC36A1) 的底物,能够竞争性抑制 L-脯氨酸的摄取。
T19931 Gentisein

NSC 329491,NSC329491,NSC-329491

Serotonin Transporter Neuroscience
Gentisein (NSC-329491) 是 Mangiferin 的主要代谢物,有效抑制 5-HT 的摄取,IC50为 4.7 µM。
TL0006 Cichoric Acid

菊苣酸,Dicaffeoyltartaric acid,Chicoric Acid

Reactive Oxygen Species; HIV Protease Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
Cichoric Acid (Dicaffeoyltartaric acid) 是一种天然化合物,具有抗氧化作用。
T9352 hydrocotarnine

Others Others
hydrocotarnine 是 Cbl 的抑制剂。
T7557 Guvacine hydrochloride

GABA Receptor Membrane transporter/Ion channel; Neuroscience
Guvacine hydrochloride 是从槟榔中得到的一种生物碱,是 GABA 摄取抑制剂,IC50为 10 μM。它对几种克隆的 GABA 转运体具有适度的选择性。
T23119 Palmitoylisopropylamide

FAAH Metabolism; Neuroscience
Palmitoylisopropylamide 是一种选择性 FAAH 抑制剂,抑制[H]-AEA摄取,在低浓度下抑制细胞增殖。
T0185 Escitalopram

Seroplex,依他普仑,S-(+)-Citalopram,艾司西酞普兰,(S)-Citalopram

Dopamine Receptor; 5-HT Receptor; Serotonin Transporter; Adrenergic Receptor; AChR; Norepinephrine; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Escitalopram (Seroplex) 是一种外消旋 Citalopram 的 S-对映体,是一种选择性 5-羟色胺再摄取抑制剂,Ki=0.89 nM,比 R(-)-enantiomer 结合亲和力高 30 倍。它对多巴胺转运体和去甲肾上腺素转运体均有选择性,是一种研究抑郁症的抗抑郁药。
TMA1122 N-Feruloylserotonin

(E/Z)-Moschamine,Moschamine

Antioxidant oxidation-reduction
N-Feruloylserotonin ((E/Z)-Moschamine) 是可从 Carthamus tinctorius L. 中分离得到的一种血清素衍生物,具有抗氧化活性,有用于动脉粥样硬化和主动脉壁膨胀研究的潜能。
T8771 Pongamol

Others Others
Pongamol 是一种从 Pongamia pinnata 果实中鉴定出的铅分子,对骨骼肌细胞的葡萄糖摄取和 GLUT4 易位。
T2986 Jatrorrhizine hydrochloride

Others; 5-HT Receptor; Antibacterial; AChE GPCR/G Protein; Microbiology/Virology; Neuroscience; Others
Jatrorrhizine hydrochloride 是从小檗的根中提取的化合物,具有具有神经保护、抗菌、抗疟原虫和抗氧化活性。Jatrorrhizine hydrochloride 是一种具有口服活性和选择性的乙酰胆碱酯酶 (AChE)抑制剂,抑制去甲肾上腺素 (NE) 的摄取。
T4959 DL-Mannitol

甘露醇,Mannitol

Others Others
DL-Mannitol 是由 D-mannitol 与 L-mannitol 通过 L-mannono-1, Clactone 还原得到的。
T4912 Jatrorrhizine chloride

盐酸药根碱,Yatrorhizine chloride,Neprotine chloride

Others; 5-HT Receptor; OCT; Antibacterial; AChE GPCR/G Protein; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; Others
Jatrorrhizine chloride (Neprotine chloride) 是从黄连中分离得到的生物碱,具有神经保护、抗菌、抗氧化和抗疟原虫活性。它通过抑制摄取2转运蛋白的活性减少血清素和去甲肾上腺素的摄取。它是具有口服活性的乙酰胆碱酯酶抑制剂。
TQ0161 Mulberrin

桑黄酮,Kuwanon C

Others Others
Mulberrin (Kuwanon C) 能够抑制有机阴离子转运多肽 2B1 介导的雌酮-3-硫酸盐摄取(IC50:1.8±1.5 μM)。
TN1740 Homoeriodictyol

高胜草酚,高圣草酚

5-HT Receptor; transporter; Sodium Channel; Drug Metabolite GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Neuroscience
Homoeriodictyol 是 Eriocitrin 的代谢物,属于黄酮类。Eriocitrin 是强效抗氧化剂。
T5690 7,4'-Di-O-methylapigenin

芹菜素二甲醚,4',7-DIMETHOXY-5-HYDROXYFLAVONE

Amylase Metabolism
7,4'-Di-O-methylapigenin (4',7-DIMETHOXY-5-HYDROXYFLAVONE) 可能具有抗真菌c.zeyheri 的作用,是一种潜在的抗真菌药物。它还能抑制药物流出泵(IC50 = 51.64μg /毫升)。
TN2285 DL-Tryptophan

(±)-Tryptophan,Tryptophan,DL-色氨酸

Serotonin Transporter; Endogenous Metabolite Metabolism; Neuroscience
DL-Tryptophan ((±)-Tryptophan) 是内源性代谢产物的一种。
T2S0265 Robinin

NSC 9222,刺槐素

TLR Immunology/Inflammation
Flavone glycoside from Robinia with antibacterial and diuretic properties; derived from kaempferol.The ability of robinin to reverse the multidrug resistance of the human colon cancer cell line Colo 320 expreβing MDR1/LRP was explored by monitoring their uptake of Rhodamine 123, but was shown to have minimal effect. Robinin (NSC-9222) was detected in lysates of the human breast cancer cell line MCF-7 using liquid chromatography-tandem maβ spectrometry.
T1045 Trimipramine maleate

Surmontil maleate,马来酸三甲丙咪嗪,三甲丙咪嗪马来酸盐

Dopamine Receptor; 5-HT Receptor; Antibacterial; Adrenergic Receptor; Norepinephrine; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
Trimipramine maleate (Surmontil maleate) 是一种 5-HT 受体拮抗剂,对 5-HT1C、5-HT2和 5-HT1A 受体的 pKi 值分别为 6.39、8.10和 4.66。
T3095 Tyramine

4-hydroxyphenethylamine,酪胺,para-tyramine,p-Tyramine,mydrial,Tocosine,Uteramine

MAO; Endogenous Metabolite Metabolism; Neuroscience
Tyramine (Uteramine) 是天然存在于体内或某些食物中的氨基酸。Tyramine 有助于调节血压。
T4S0779 D-tetrahydropalmatine

Others; Dopamine Receptor GPCR/G Protein; Neuroscience; Others
D-Tetrahydropalmatine 是一种主要存在于延胡索类植物中的异喹啉生物碱。它是有机阳离子转运蛋白 1 抑制剂。它是多巴胺受体拮抗剂,对 D1 受体具有优先亲和力。
TN2111 Prunin

Naringenin 7-0-glucoside,柚皮素-7-O-葡萄糖苷

Phosphatase; Anti-infection; Virus Protease Metabolism; Microbiology/Virology
Prunin (Naringenin 7-0-glucoside) 是一种人肠道病毒 A71 抑制剂。它抑制蛋白酪氨酸磷酸酶 1B,IC50值为 5.5 μM。
T0791 Reserpine

利血平,Serpalan,Serpasil,Serpivite

Others; Potassium Channel; MRP; Monoamine Transporter; Autophagy Autophagy; Immunology/Inflammation; Membrane transporter/Ion channel; Others
Reserpine (Serpalan) 是一种从催吐萝芙木的根中发现的生物碱。它抑制去甲肾上腺素吸收到储存囊泡中,导致中枢和外周轴突末端的儿茶酚胺和血清素耗尽。它可作为抗高血压药和抗精神病药以及研究工具。
T6S0232 Eriodictyol

圣草酚,Huazhongilexone

Influenza Virus; DNA/RNA Synthesis; Nrf2; Endogenous Metabolite Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology
Eriodictyol (Huazhongilexone) 是从中草药中得到的一种黄酮类天然产物,具有抗氧化、抗炎和抗糖尿病作用。它还是一种流感依赖 RNA 的RNA 聚合酶抑制剂,IC50为 18 nM。它可诱导Nrf2信号通路。
T1311 4-aminobenzoic acid

PABA,Vitamin H1,Vitamin Bx,para-Aminobenzoic acid,对氨基苯甲酸

Endogenous Metabolite Metabolism
4-aminobenzoic acid 是一种具有紫外线吸收和抗纤维化特性的有机酸。当暴露在光线下时,4-aminobenzoic acid 吸收紫外线并通过光化学反应释放多余的能量,这可能会对DNA造成损害。4-aminobenzoic acid 还可以增加组织水平的摄氧量,并可能增强单胺氧化酶(MAO)活性以促进血清素的降解,过量可能导致纤维化变化。
T2P2923 Stearic acid

硬脂酸,Isostearic acid,Octadecanoic acid,Cetylacetic acid

Phosphatase; Endogenous Metabolite Metabolism
Stearic acid (Cetylacetic acid) 是长链饱和脂肪酸,存在于许多动植物油脂中。
TN1013 Cucurbitacin D

Apoptosis Apoptosis
Cucurbitacin D 是一种从 Ecballium elaterium (L.)分离出来的三萜类化合物,具有抗癌抗肿瘤活性,抑制转移性 PrC 中的葡萄糖摄取和乳酸产生,诱导独立于 ERK1/2 激活的炎症小体激活。 Cucurbitacin D 是巨噬细胞中的一种新的炎症小体激活剂,通过调节 JAK/STAT3、PI3K/Akt/mTOR 和 MAPK 信号通路抑制 HepG2 细胞增殖并诱导细胞凋亡, 可用于研究宫颈癌、白血病和前列腺癌。
T5S1172 Tiliroside

银椴甙,Tribuloside,银椴苷;椴树苷

Antioxidant oxidation-reduction
Tiliroside (Tribuloside) 是糖苷类黄酮,是 α-淀粉酶的非竞争性抑制剂(Ki:84.2 μM)。它抑制胃肠道中碳水化合物的消化和葡萄糖的吸收,具有抗糖尿病作用。
T4962 Zingibroside R1

Ginsenoside Z-R1,姜状三七皂苷R1,姜状三七苷R1

HIV Protease Microbiology/Virology; Proteases/Proteasome
Zingibroside R1 (Ginsenoside Z-R1) 是分离自Panax japonicasC. A. Meyer 根部的一种三萜皂苷,有HIV-1、抗肿瘤和抗血管生成活性。它对 EAT 细胞的 2-脱氧-D-葡萄糖的摄取具有抑制作用,IC50值为91.3 μM。
T3933 Jatrorrhizine

Yatrorizine,neprotin,药根碱

MAO; 5-HT Receptor; Antibacterial; AChE GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience
Jatrorrhizine (neprotin) 是一种从黄连中分离得到的生物碱,具有抗菌、抗氧化、抗疟原虫和神经保护活性。它通过抑制 uptake-2 transporter 的活性减少血清素和去甲肾上腺素的摄取。它是一种有口服活性的乙酰胆碱酯酶制剂。
T25533 Indalpine

LM-5008,Lipstene,Indalpino,LM 5008,LM5008

Indalpine is used as a selective 5-hydroxytryptamine uptake inhibitor.
T80013 Arecaidine hydrobromide

GABA Receptor Membrane transporter/Ion channel; Neuroscience
Arecaidine hydrobromide,一种吡啶生物碱,有效抑制GABA吸收。作为H+偶联的氨基酸转运蛋白1(PAT1,SLC36A1)的底物,它竞争性地抑制L-脯氨酸的摄取。
TN7473 5-O-Coumaroylquinic acid

Others Others
5-O-Coumaroylquinic acid (3-O-Coumaroylquinic acid), exhibits significant inhibition of PTP1B and a concentration-dependent inhibitory effect on α-glucosidase, thereby demonstrating anti-hyperglycemic properties. Additionally, this compound enhances glucose uptake and inhibits PTP1B in vitro, emphasizing its potential therapeutic applications in glucose regulation.
T39613 11-epi-mogroside V

Others Others
11-epi-mogroside V, a compound found in the fruit of Siraitia grosvenori, possesses significant bioactivity by enhancing glucose uptake in vitro, specifically in human HepG2 cells.
TN4822 Prehelminthosporol

Antifection Microbiology/Virology
Prehelminthosporol is a phytotoxin, it may play an important role in pathogenesis by killing or weakening plant cells in advance of the growing hyphae and facilitating nutrient uptake and further growth of the fungus in plant tissue.
TN7300 1-O-p-Coumaroyl-β-D-glucose

Others Others
1-O-p-Coumaroyl-β-D-glucose 能够提升HuH7细胞对葡萄糖的吸收,其可从丝瓜提取。
TN1368 Alisol C

Others Others
Alisol C can improve glucose uptake in Hep G2 cells, it may be one of the therapeutic material basis in hypoglycemic activities in A. orientalis. Alisol C,16,23-oxido-alisol B and alisol O in Zexie may cause nephrotoxicity.
T37232 (+)-Geodin

Others Others
(+)-Geodin is a fungal metabolite. It increases the fibrinolytic activity of bovine aortic endothelial cells (BAECs) when used at concentrations ranging from 50 to 150 μM. (+)-Geodin (1-100 μg/ml) also increases 2-deoxyglucose uptake by rat adipocytes.
TN4944 Santamarine

Caspase Apoptosis; Proteases/Proteasome
Santamarine has significant anticancer activity, can inhibit L1210 cells because of its cytotoxic,cytostatic and blocking mitosis and reducing uptake of thymidine. Santamarine and reynosin show bactericidal activity against clinical strains of Mycobacterium tuberculosis.
TN4905 Rehmannic acid

NADPH-oxidase Immunology/Inflammation
Rehmannic acid and oleanolic acetate inhibit succinoxidase activity. Both Rehmannic acid and Icterogenin are potent uncouplers, abolishing the phosphate uptake, the respiration being inhibited by the former and increased by the latter.
T75436 Jatrorrhizine hydroxide

Others Others
Jatrorrhizine hydroxide, 一种从黄连中提取的生物碱,展现了神经保护、抗菌、抗疟原虫及抗氧化的活性。作为一种高效的乙酰胆碱酯酶(AChE)抑制剂(IC50=872 nM),其对BuChE的选择性高达115倍。此外,Jatrorrhizine hydroxide还能通过抑制uptake-2 transporter活性来减少血清素(5-HT)和去甲肾上腺素(NE)的摄取,表现出口服活性。
TN4691 Octadecyl caffeate

Others Others
z-Octadecyl caffeate may have pain-relieving activity. Octadecyl caffeate and coptisonine can stimulate glucose uptake at 25 and 50 ug/mL. Octadecyl caffeate and octadecyl coumarate applied to the surface of susceptible varieties in laboratory bioassays r
TN1462 Cajanin

2',4',5-三羟基-7-甲氧基异黄酮,木豆异黄酮

ERK; MEK; Akt Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling
Cajanin has potential hypolipidemic effects,possibly via up-regulating the ABCA1 protein expression,subsequently resulting in increased macrophage cholesterol efflux and RCT, it can significantly improve basal glucose uptake in HepG2 cells, its improving effect is concentration dependent, it exhibits effects stronger than that of rosiglitazone, which has been used as an antidiabetic drug.
T3S0964 Thermopsoside

Chrysoeriol-7-O-glucoside

Others Others
Chrysoeriol-7-O-glucoside can strongly inhibit the classical pathway of the complement system.Chrysoeriol-7-O-d-glucoside and luteolin-7-O-d-glucoside can inhibit palmitic acid uptake into small intestinal brush border membrane, apigenin-7-O-d-glucoside can inhibit alpha-amylase activity; they can enhance norepinephrine-induced lipolysis in fat cells.
T38394 PSMα3

Others Others
PSMα3 is a peptide compound that can be utilized to induce tolerance in dendritic cells (DCs) for DC vaccination strategies. It effectively penetrates and modulates human monocyte-derived DCs by modifying the maturation process induced by TLR2 or TLR4. Additionally, PSMα3 inhibits the production of both pro- and anti-inflammatory cytokines and decreases antigen uptake. Notably, PSMα3 is a significant virulence factor released by the most pathogenic strains of methicillin-resistant Staphylococcus...
T21772 Reserpine hydrochloride

Reserpine hydrochloride 是一种从催吐萝芙木的根中发现的生物碱。它抑制去甲肾上腺素吸收到储存囊泡中,导致中枢和外周轴突末端的儿茶酚胺和血清素耗尽。它可作为抗高血压药和抗精神病药以及研究工具。
T80014 Guvacine hydrobromide

GABA Receptor Membrane transporter/Ion channel; Neuroscience
Guvacine hydrobromide为槟榔中提取的生物碱,具有作为GABA摄取抑制剂的活性。该化合物对大鼠GAT-1、GAT-2和GAT-3的GABA摄取抑制作用具有不同的IC50值,分别为39 μM、58 μM及378 μM。
TN4997 Serpentine

IGF-1R Tyrosine Kinase/Adaptors
Serpentine 是一种玫瑰花根中的生物碱,可用作胰岛素增敏剂,以协助胰岛素降低血糖。Serpentine 可激活 AMPK 磷酸化,从而刺激C2C12细胞对葡萄糖的摄取。Serpentine 可增加了肌肉组织中GSK-3β mRNA的表达,从而增强葡萄糖摄取。Serpentine 显著增加胰高血糖素分泌和肝糖异生。在高脂肪饮食/链脲佐菌素(HFD/STZ)诱导的糖尿病小鼠中,Serpentine 显著延长了胰岛素的降血糖时间,显著降低了外源性胰岛素的使用,抑制了内源性胰岛素的分泌。
T37911 cis-Resveratrol

顺式白藜芦醇,(Z)-Resveratrol

Others Others
Resveratrol is a potent phenolic antioxidant found in grapes, red wine, and various berries that also has antiproliferative and anti-inflammatory activity. cis-Resveratrol is the double bond isomer of trans-resveratrol, the more often studied and naturally abundant of the two resveratrol isomers. cis-Resveratrol exhibits antioxidant activity in the &#181M range similar to that observed with trans-resveratrol. It blocks production of reactive oxygen species (ROS) by inhibition of NAD(P)H oxidase ...

天然产物

Guvacine ethyl ester
Cat.No: TJS0123
Synonym: 槟榔碱,PT00442-2
Target: Others
Arecaidine hydrochloride
Cat.No: T5799
Synonym:
Target: Others
Gentisein
Cat.No: T19931
Synonym: NSC 329491,NSC329491,NSC-329491
Target: Serotonin Transporter
Cichoric Acid
Cat.No: TL0006
Synonym: 菊苣酸,Dicaffeoyltartaric acid,Chicoric Acid
Target: Reactive Oxygen Species, HIV Protease
hydrocotarnine
Cat.No: T9352
Synonym:
Target: Others
Guvacine hydrochloride
Cat.No: T7557
Synonym:
Target: GABA Receptor
Palmitoylisopropylamide
Cat.No: T23119
Synonym:
Target: FAAH
Escitalopram
Cat.No: T0185
Synonym: Seroplex,依他普仑,S-(+)-Citalopram,艾司西酞普兰,(S)-Citalopram
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Adrenergic Receptor, AChR, Norepinephrine, Histamine Receptor
N-Feruloylserotonin
Cat.No: TMA1122
Synonym: (E/Z)-Moschamine,Moschamine
Target: Antioxidant
Pongamol
Cat.No: T8771
Synonym:
Target: Others
Jatrorrhizine hydrochloride
Cat.No: T2986
Synonym:
Target: Others, 5-HT Receptor, Antibacterial, AChE
DL-Mannitol
Cat.No: T4959
Synonym: 甘露醇,Mannitol
Target: Others
Jatrorrhizine chloride
Cat.No: T4912
Synonym: 盐酸药根碱,Yatrorhizine chloride,Neprotine chloride
Target: Others, 5-HT Receptor, OCT, Antibacterial, AChE
Mulberrin
Cat.No: TQ0161
Synonym: 桑黄酮,Kuwanon C
Target: Others
Homoeriodictyol
Cat.No: TN1740
Synonym: 高胜草酚,高圣草酚
Target: 5-HT Receptor, transporter, Sodium Channel, Drug Metabolite
7,4'-Di-O-methylapigenin
Cat.No: T5690
Synonym: 芹菜素二甲醚,4',7-DIMETHOXY-5-HYDROXYFLAVONE
Target: Amylase
DL-Tryptophan
Cat.No: TN2285
Synonym: (±)-Tryptophan,Tryptophan,DL-色氨酸
Target: Serotonin Transporter, Endogenous Metabolite
Robinin
Cat.No: T2S0265
Synonym: NSC 9222,刺槐素
Target: TLR
Trimipramine maleate
Cat.No: T1045
Synonym: Surmontil maleate,马来酸三甲丙咪嗪,三甲丙咪嗪马来酸盐
Target: Dopamine Receptor, 5-HT Receptor, Antibacterial, Adrenergic Receptor, Norepinephrine, Histamine Receptor
Tyramine
Cat.No: T3095
Synonym: 4-hydroxyphenethylamine,酪胺,para-tyramine,p-Tyramine,mydrial,Tocosine,Uteramine
Target: MAO, Endogenous Metabolite
D-tetrahydropalmatine
Cat.No: T4S0779
Synonym:
Target: Others, Dopamine Receptor
Prunin
Cat.No: TN2111
Synonym: Naringenin 7-0-glucoside,柚皮素-7-O-葡萄糖苷
Target: Phosphatase, Anti-infection, Virus Protease
Reserpine
Cat.No: T0791
Synonym: 利血平,Serpalan,Serpasil,Serpivite
Target: Others, Potassium Channel, MRP, Monoamine Transporter, Autophagy
Eriodictyol
Cat.No: T6S0232
Synonym: 圣草酚,Huazhongilexone
Target: Influenza Virus, DNA/RNA Synthesis, Nrf2, Endogenous Metabolite
4-aminobenzoic acid
Cat.No: T1311
Synonym: PABA,Vitamin H1,Vitamin Bx,para-Aminobenzoic acid,对氨基苯甲酸
Target: Endogenous Metabolite
Stearic acid
Cat.No: T2P2923
Synonym: 硬脂酸,Isostearic acid,Octadecanoic acid,Cetylacetic acid
Target: Phosphatase, Endogenous Metabolite
Cucurbitacin D
Cat.No: TN1013
Synonym:
Target: Apoptosis
Tiliroside
Cat.No: T5S1172
Synonym: 银椴甙,Tribuloside,银椴苷;椴树苷
Target: Antioxidant
Zingibroside R1
Cat.No: T4962
Synonym: Ginsenoside Z-R1,姜状三七皂苷R1,姜状三七苷R1
Target: HIV Protease
Jatrorrhizine
Cat.No: T3933
Synonym: Yatrorizine,neprotin,药根碱
Target: MAO, 5-HT Receptor, Antibacterial, AChE
Indalpine
Cat.No: T25533
Synonym: LM-5008,Lipstene,Indalpino,LM 5008,LM5008
Target:
Arecaidine hydrobromide
Cat.No: T80013
Synonym:
Target: GABA Receptor
5-O-Coumaroylquinic acid
Cat.No: TN7473
Synonym:
Target: Others
11-epi-mogroside V
Cat.No: T39613
Synonym:
Target: Others
Prehelminthosporol
Cat.No: TN4822
Synonym:
Target: Antifection
1-O-p-Coumaroyl-β-D-glucose
Cat.No: TN7300
Synonym:
Target: Others
Alisol C
Cat.No: TN1368
Synonym:
Target: Others
(+)-Geodin
Cat.No: T37232
Synonym:
Target: Others
Santamarine
Cat.No: TN4944
Synonym:
Target: Caspase
Rehmannic acid
Cat.No: TN4905
Synonym:
Target: NADPH-oxidase
Jatrorrhizine hydroxide
Cat.No: T75436
Synonym:
Target: Others
Octadecyl caffeate
Cat.No: TN4691
Synonym:
Target: Others
Cajanin
Cat.No: TN1462
Synonym: 2',4',5-三羟基-7-甲氧基异黄酮,木豆异黄酮
Target: ERK, MEK, Akt
Thermopsoside
Cat.No: T3S0964
Synonym: Chrysoeriol-7-O-glucoside
Target: Others
PSMα3
Cat.No: T38394
Synonym:
Target: Others
Reserpine hydrochloride
Cat.No: T21772
Synonym:
Target:
Guvacine hydrobromide
Cat.No: T80014
Synonym:
Target: GABA Receptor
Serpentine
Cat.No: TN4997
Synonym:
Target: IGF-1R
cis-Resveratrol
Cat.No: T37911
Synonym: 顺式白藜芦醇,(Z)-Resveratrol
Target: Others
Cat. No. Product Name Species Expression System
TMPH-01468 SLC31A1 Protein, Human, Recombinant (His & SUMO)

Copper transporter 1,SLC31A1,High affinity copper uptake...

Human E. coli
SLC31A1 Protein, Human, Recombinant (His & SUMO) is expressed in in vitro E. coli expression system.
TMPH-02006 STRA6 Protein, Human, Recombinant (hFc)

STRA6,Retinol-binding protein receptor STRA6,Receptor for re...

Human HEK293 Cells
STRA6 Protein, Human, Recombinant (hFc) is expressed in HEK293.
TMPH-02646 Erythroferrone Protein, Mouse, Recombinant (His)

Erythroferrone,Myonectin,Erfe,Complement C1q tumor necrosis ...

Mouse P. pastoris (Yeast)
Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake. Erythroferrone Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted m...
TMPJ-00059 IL-7 Protein, Human, Recombinant (His)

Interleukin-7,IL7,白细胞介素,IL-7,白介素

Human HEK293 Cells
Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. Human IL7 cDNA encodes a 177 amino acid precursor protein containing a 25 amino acid signal peptide and a 152 amino acid mature protein. Human and mouse IL7 share 65% sequence identity in the mature region and both exhibit cross-spe...
TMPY-02907 FGF-19 Protein, Human, Recombinant

fibroblast growth factor 19,FGF19

Human E. coli
FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF19 interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by KL, KLB and heparan sulfate glycosaminoglyca...
TMPY-00395 Insulin Protein, Human, Recombinant

IDDM1,MODY10,ILPR,IDDM2,IRDN,IDDM,insulin,INS

Human P. pastoris (Yeast)
INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. The binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Diseases associated with ...
TMPY-01280 FOLR2 Protein, Human, Recombinant (His)

FBP,β-HFR,FR-P3,BETA-HFR,folate receptor 2 (fetal),FR-BETA,F...

Human HEK293 Cells
Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant tissues. Members of the Folate receptor family members (FOLRs) have a high affinity for folic acid and for several reduced folic acid derivatives. They mediate the delivery of 5-methyltetrahydrofolate to the interior of, out of within, or between cells in a process known as potoc...
TMPH-02600 C1QL3 Protein, Mouse, Recombinant (His & Myc)

C1ql,Gliacolin,C1q and tumor necrosis factor-related protein...

Mouse Baculovirus Insect Cells
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Plays a role in glucose homeostasis. Via AMPK signaling pathway, stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, reduces the expression of gluconeogenic enzymes G6PC1 and PCK1 and hence decreases de novo glucose production.
TMPH-02807 NPTXR Protein, Mouse, Recombinant (His & Myc)

Neuronal pentraxin receptor,Nptxr

Mouse Baculovirus Insect Cells
May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
TMPH-01612 LSR Protein, Human, Recombinant (His)

Lipolysis-stimulated lipoprotein receptor,Angulin-1,LSR

Human E. coli
Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells.
TMPH-01301 Erythroferrone Protein, Human, Recombinant (His & SUMO)

Myonectin,Erythroferrone,ERFE,Complement C1q tumor necrosis ...

Human E. coli
Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake.
TMPH-02808 NPTX1 Protein, Mouse, Recombinant (His)

Nptx1,Neuronal pentraxin-1,Neuronal pentraxin I

Mouse E. coli
May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
TMPH-01381 GDNF Protein, Human, Recombinant (His & SUMO)

Astrocyte-derived trophic factor,GDNF,Glial cell line-derive...

Human E. coli
Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. GDNF Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 31.1 kDa and the accession number is P39905.
TMPH-00706 MppA Protein, E. coli, Recombinant (His & SUMO)

Periplasmic murein peptide-binding protein,mppA

E. coli E. coli
Essential for the uptake of the murein peptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate. Also transports some alpha-linked peptides such as Pro-Phe-Lys with low affinity. The transport is effected by the oligopeptide permease system.
TMPH-02333 SLC25A19 Protein, Human, Recombinant (His)

Mitochondrial thiamine pyrophosphate transporter,SLC25A19,So...

Human E. coli
Mitochondrial transporter mediating uptake of thiamine pyrophosphate (ThPP) into mitochondria. SLC25A19 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 37.0 kDa and the accession number is Q9HC21.
TMPH-02120 SLC5A5 Protein, Human, Recombinant (His)

Sodium-iodide symporter,SLC5A5,Natrium iodide transporter,So...

Human E. coli
Mediates iodide uptake in the thyroid gland. SLC5A5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 17.4 kDa and the accession number is Q92911.
TMPH-02124 SLC23A2 Protein, Human, Recombinant (His)

Nucleobase transporter-like 1 protein,SLC23A2,Na(+)/L-ascorb...

Human E. coli
Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate. SLC23A2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 71.3 kDa and the accession number is Q9UGH3.
TMPH-01540 Intelectin-1/ITLN1 Protein, Human, Recombinant (His & Myc)

Galactofuranose-binding lectin,Endothelial lectin HL-1,Intel...

Human E. coli
Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner. Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-ulosonic acid (KDO). Binds to glycans from Gram-positive and Gram-negative bacteria, including K.pneumoniae, S.pneumoniae, Y.pestis, P.mirabilis and P.vulgaris. Does not ...
TMPH-03373 SLC2A1 Protein, Rat, Recombinant (His & Myc)

Glucose transporter type 1, erythrocyte/brain,Solute carrier...

Rat E. coli
Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors. SLC2A1 ...
TMPH-00628 GltI/YbeJ Protein, E. coli, Recombinant (His & SUMO)

gltI,Glutamate/aspartate import solute-binding protein

E. coli E. coli
Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Binds to both glutamate and aspartate. GltI/YbeJ Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 47.2 kDa and the accession number is P37902.
TMPH-02122 SLC2A1 Protein, Human, Recombinant (His & Myc)

Glucose transporter type 1, erythrocyte/brain,HepG2 glucose ...

Human E. coli
Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors. SLC2A1 ...
TMPH-02897 SPINK1 Protein, Mouse, Recombinant (His)

Serine protease inhibitor Kazal-type 3,Serine protease inhib...

Mouse P. pastoris (Yeast)
Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin-catalyzed premature activation of zymogens.; In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production. SPINK1 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 8.1 kDa and the accession number is P09036.
TMPH-00298 Resistin Protein, Bovine, Recombinant (His)

Resistin,RETN

Bovine E. coli
Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes. Resistin Protein, Bovine, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 13.6 kDa and the accession number is Q762I5.
TMPH-03231 AFP2 Protein, Raphanus sativus, Recombinant (His & SUMO)

Cysteine-rich antifungal protein 2,Defensin-like protein 2,R...

Raphanus sativus E. coli
Possesses antifungal activity sensitive to inorganic cations. Induces potential changes in fungal membranes and increased K(+) efflux and Ca(2+) uptake. AFP2 Protein, Raphanus sativus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 21.7 kDa and the accession number is P30230.
TMPH-01578 KRT18 Protein, Human, Recombinant (His)

Keratin, type I cytoskeletal 18,KRT18,Cell proliferation-ind...

Human HEK293 Cells
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells. When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
TMPH-03327 MBL2 Protein, Rat, Recombinant (His)

Mannan-binding protein,Ra-reactive factor polysaccharide-bin...

Rat E. coli
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. MBL2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 30.0 kDa and the accession num...
TMPJ-00533 LYVE1 Protein, Human, Recombinant (His)

XLKD1,Cell Surface Retention Sequence-Binding Protein 1,Extr...

Human HEK293 Cells
Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 is a single-pass type I membrane protein. LYVE-1 is a CD44 homolog found primarily on lymphatic endothelial cells 1. LYVE-1 mainly expressed in endothelial cells lining lymphatic vessels. While LYVE-1 functions is a Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. LYVE-1 plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention s...
TMPY-02983 LYVE1 Protein, Mouse, Recombinant (hFc)

1200012G08Rik,Lyve-1,lymphatic vessel endothelial hyaluronan...

Mouse HEK293 Cells
LYVE1, also known as LYVE-1, is a type I integral membrane glycoprotein. It contains 1 Link domain and is mainly expressed in endothelial cells lining lymphatic vessels. LYVE1 acts as a receptor and binds to both soluble and immobilized hyaluronan. It may function in lymphatic hyaluronan transport and have a role in tumor metastasis. LYVE1 also is a cell surface receptor on lymphatic endothelial cells that can be used as a lymphatic endothelial cell marker, and sort these cells for experimental ...
TMPH-00284 MBP-C Protein, Bovine, Recombinant (His)

Mannose-binding protein C,MBL,Mannan-binding protein

Bovine Baculovirus Insect Cells
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. MBP-C Protein, Bovine, Recombinant (His) is expressed in Baculovirus insect cells with N-10xHis tag. The predicted molecular weight is 26.9 kDa and the accession...
TMPH-02824 Perforin-1/PRF1 Protein, Mouse, Recombinant (His)

Lymphocyte pore-forming protein,Cytolysin,Perforin-1,Prf1

Mouse E. coli
Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.
TMPH-00406 ctfB Protein, Clostridium acetobutylicum, Recombinant (His & Myc)

Butyrate--acetoacetate CoA-transferase subunit B,ctfB,Coat B...

Clostridium acetobutylicum E. coli
Involved in solventogenic switch which allows C.acetobutylicum to uptake acid and produce solvents. Acts mainly to detoxify the medium by removing the acetate and butyrate excreted earlier in the fermentation. ctfB Protein, Clostridium acetobutylicum, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 30.6 kDa and the accession number is P23673.
TMPH-02447 GH Protein, Rhesus macaque, Recombinant (His & Myc)

Growth hormone,Growth hormone 1,Somatotropin,GH1,Pituitary g...

Rhesus E. coli
Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. GH Protein, Rhesus macaque, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 29.7 kDa and the accession number is ...
TMPH-03127 GH Protein, Pig, Recombinant (His & Myc)

GH1,Growth hormone,Somatotropin

Sus scrofa (Pig) E. coli
Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. GH Protein, Pig, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 29.4 kDa and the accession number is P01248.
TMPZ-00002 GH2 Protein, Human, Recombinant (His)

Growth hormone 2,Placenta-specific growth hormone

Human HEK294 Cells
GH2 Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. GH2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.01 kDa and the accession number is P01242.
TMPK-01228 MARCO Protein, Human, Recombinant (His)

Ly112,SCARA2,AI323439,MARCO

Human HEK293 Cells
Macrophage receptor with collagenous structure (MARCO) is the predominant scavenger receptor for recognition and binding of silica particles by alveolar macrophages (AM). MARCO contributes to normal cholesterol uptake in macrophages; therefore, in the absence of MARCO, macrophages are more susceptible to a greater inflammatory response by particulates known to cause NLRP3 inflammasome activation and the effect is due to increased LMP.
TMPH-02611 Langerin/CD207 Protein, Mouse, Recombinant (His)

C-type lectin domain family 4 member K,Langerin,Cd207

Mouse E. coli
Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells.
TMPJ-00378 Transferrin Receptor/TFRC Protein, Human, Recombinant (aa 101-760, His)

p90,TfR,T9,Trfr,Transferrin receptor protein 1,TR

Human HEK293 Cells
Transferrin receptor protein 1 (TFRC) belongs to the peptidase M28 family that is synthesized as a 172 amino acid (aa). TFRC regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. It binds one transferrin or HFE molecule per subunit and binds the HLA class II histocompatibility antigen, DR1. It Interacts with SH3BP3 and STEAP3, facilitates TFRC endocytosis in erythroid precursor cells. Cellular uptake of iron o...
TMPH-00039 Single-strand DNA-binding protein Protein, Agrobacterium fabrum, Recombinant (His & Myc)

Single-strand DNA-binding protein,63.5 kDa virulence protein...

Agrobacterium fabrum E. coli
Involved in DNA transformation; mediates the nuclear uptake of single-stranded DNA copies of the transferred DNA (T-DNA) element. Binds single-stranded but not double-stranded DNA regardless of nucleotide sequence composition. Single-strand DNA-binding protein Protein, Agrobacterium fabrum, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 70.3 kDa and the accession number is P08062.
TMPY-02711 Ferritin heavy chain 1/FTH1 Protein, Human, Recombinant

FHC,FTHL6,FTH,PIG15,PLIF,ferritin, heavy polypeptide 1,HFE5

Human E. coli
FTH1 (ferritin, heavy polypeptide 1) is the heavy subunit of ferritin which is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative dis...
TMPH-01577 KRT18 Protein, Human, Recombinant (E. coli, His)

Keratin-18,KRT18,Cytokeratin-18,Cell proliferation-inducing ...

Human E. coli
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells. When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection. KRT18 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 52.0 kDa and the accession number is P05783.
TMPJ-00795 Growth Hormone Protein, Mouse, Recombinant

Gh1,Somatotropin,Gh,Growth Hormone

Mouse E. coli
Somatotropin(GH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. GH stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
TMPH-03400 SLC17A6 Protein, Rat, Recombinant (His)

Slc17a6,Vesicular glutamate transporter 2,Solute carrier fam...

Rat P. pastoris (Yeast)
Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. Involved in the regulation of retinal hyaloid vessel regression during postnatal development. May also play a role in the endocrine glutamatergic system of other tissues such as pineal gland and pancreas. SLC17A6 Protein, Rat, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 11.1 kDa an...
TMPH-01050 CPT2 Protein, Human, Recombinant (His & Myc)

Carnitine O-palmitoyltransferase 2, mitochondrial,CPT II,Car...

Human E. coli
Involved in the intramitochondrial synthesis of acylcarnitines from accumulated acyl-CoA metabolites. Reconverts acylcarnitines back into the respective acyl-CoA esters that can then undergo beta-oxidation, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Active with medium (C8-C12) and long-chain (C14-C18) acyl-CoA esters. CPT2 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with ...
TMPJ-01130 NPTX1 Protein, Human, Recombinant (His)

Neuronal pentraxin-1,NPTX1,NP1

Human HEK293 Cells
Neuronal Pentraxin (NPTX1, NP1) is a secreted glycoprotein within the Pentraxin family. NPTX1 is co‑expressed and forms heteromultimers with the related secreted protein, NPTX2/NARP, NPTXR (Neuronal Pentraxin Receptor) at excitatory synapses. Mature human NPTX1 shares 97% aa sequence identity with mouse, and rat NPTX1. It is produced by hippocampal, cerebral and cerebellar neurons, retinal ganglia and the inner nuclear layer of the retina. It is enriched on presynaptic axonal membranes where it ...
TMPJ-00811 IGFBP-1 Protein, Human, Recombinant (His)

Insulin-like growth factor-binding protein 1,PP12,IGFBP-1,IG...

Human HEK293 Cells
Insulin-like growth factor-binding protein 1 (IGFBP1) is encoded by 259 amino acid (aa) with 25 aa residue signal peptide that is processed to generate the 234 aa residue mature protein. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. Regulation of Insulin-like Growth Factor (IGF) transp...
TMPK-00150 FOLR1 Protein, Human, Recombinant (His & Avi)

Folate receptor 1,Folbp1,Folate receptor alpha,FR-alpha,FR a...

Human HEK293 Cells
Folate Receptor 1 (FOLR1), also known as Folate Receptor alpha and Folate Binding Protein (FBP), is a 37 - 42 kDa protein that mediates the cellular uptake of folic acid and reduced folates. Dietary folates are required for many key metabolic processes including nucleotide and methionine synthesis, the interconversion of glycine and serine, and histidine breakdown. FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into t...
TMPJ-00756 Apolipoprotein E/APOE3 Protein, Human, Recombinant (His)

Apolipoprotein E,Apo-E,APOE,ApoE3

Human HEK293 Cells
ApoE, a glycoprotein, is a structural component of very low density lipoprotein (vLDL) synthesized by the liver and intestinally synthesized chylomicrons . ApoE is also a constituent of a subclass of high density of lipoproteins (HDL) involved in cholesterol transport .ApoE mediates high affinity binding of chylomicrons and vLDL particles to the LDL receptor, allowing for specific uptake of these particles by the liver, preventing the accumulation of cholesterol rich particles in the plasma .Apo...
TMPJ-00761 FTH Protein, Human, Recombinant (His)

FTHL6,Cell proliferation-inducing gene 15 protein,Ferritin h...

Human E. coli
Ferritin heavy polypeptide 1(FTH1), is a ubiquitous intracellular protein which stores iron in a soluble, non-toxic, readily available form. FTH1 has ferroxidase activity and is important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Ferritin is composed of 24 subunits of the light and heavy ferritin chains. It plays a role in delivery of iron to cells and mediates iron uptake in capsule cells of the developing kidney. Variation of...
TMPJ-00981 PTX3 Protein, Mouse, Recombinant (His)

alpha-induced protein 5,pentraxin 3, long,pentaxin-related g...

Mouse HEK293 Cells
Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. It’s subunit is a disulfide-linked homooctamer that binds to C1q. PTX3 concentration is elevated in the joint fluid of patients with rheumatoid arthritis (RA), indicating that PTX3 may be a potential mediator...
TMPY-01580 PRSS2 Protein, Mouse, Recombinant (His)

Tesp4,protease, serine 2,Try2,Ta,TRY8,TRYP,Prss2

Mouse HEK293 Cells
Trypsin-2, also known as Trypsin II, Anionic trypsinogen, Serine protease 2, PRSS2 and TRY2, is a secreted protein that belongs to the trypsin serine protease family including Trypsin, PRSS1, PRSS2 and PRSS3. It consists of a signal peptide (residues 1-15), a pro region (residues 16-23), and a proteolytically active mature chain (residues 24-247). PRSS2 contains one peptidase S1 domain. It is secreted into the duodenum, hydrolysing peptides into their smaller building blocks, which is necessary ...
------------------------ 更多 ------------------------

重组蛋白

SLC31A1 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01468
Species: Human
Expression System: E. coli
STRA6 Protein, Human, Recombinant (hFc)
Cat.No: TMPH-02006
Species: Human
Expression System: HEK293 Cells
Erythroferrone Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02646
Species: Mouse
Expression System: P. pastoris (Yeast)
IL-7 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00059
Species: Human
Expression System: HEK293 Cells
FGF-19 Protein, Human, Recombinant
Cat.No: TMPY-02907
Species: Human
Expression System: E. coli
Insulin Protein, Human, Recombinant
Cat.No: TMPY-00395
Species: Human
Expression System: P. pastoris (Yeast)
FOLR2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01280
Species: Human
Expression System: HEK293 Cells
C1QL3 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02600
Species: Mouse
Expression System: Baculovirus Insect Cells
NPTXR Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02807
Species: Mouse
Expression System: Baculovirus Insect Cells
LSR Protein, Human, Recombinant (His)
Cat.No: TMPH-01612
Species: Human
Expression System: E. coli
Erythroferrone Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01301
Species: Human
Expression System: E. coli
NPTX1 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02808
Species: Mouse
Expression System: E. coli
GDNF Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01381
Species: Human
Expression System: E. coli
MppA Protein, E. coli, Recombinant (His & SUMO)
Cat.No: TMPH-00706
Species: E. coli
Expression System: E. coli
SLC25A19 Protein, Human, Recombinant (His)
Cat.No: TMPH-02333
Species: Human
Expression System: E. coli
SLC5A5 Protein, Human, Recombinant (His)
Cat.No: TMPH-02120
Species: Human
Expression System: E. coli
SLC23A2 Protein, Human, Recombinant (His)
Cat.No: TMPH-02124
Species: Human
Expression System: E. coli
Intelectin-1/ITLN1 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01540
Species: Human
Expression System: E. coli
SLC2A1 Protein, Rat, Recombinant (His & Myc)
Cat.No: TMPH-03373
Species: Rat
Expression System: E. coli
GltI/YbeJ Protein, E. coli, Recombinant (His & SUMO)
Cat.No: TMPH-00628
Species: E. coli
Expression System: E. coli
SLC2A1 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-02122
Species: Human
Expression System: E. coli
SPINK1 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02897
Species: Mouse
Expression System: P. pastoris (Yeast)
Resistin Protein, Bovine, Recombinant (His)
Cat.No: TMPH-00298
Species: Bovine
Expression System: E. coli
AFP2 Protein, Raphanus sativus, Recombinant (His & SUMO)
Cat.No: TMPH-03231
Species: Raphanus sativus
Expression System: E. coli
KRT18 Protein, Human, Recombinant (His)
Cat.No: TMPH-01578
Species: Human
Expression System: HEK293 Cells
MBL2 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03327
Species: Rat
Expression System: E. coli
LYVE1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00533
Species: Human
Expression System: HEK293 Cells
LYVE1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02983
Species: Mouse
Expression System: HEK293 Cells
MBP-C Protein, Bovine, Recombinant (His)
Cat.No: TMPH-00284
Species: Bovine
Expression System: Baculovirus Insect Cells
Perforin-1/PRF1 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02824
Species: Mouse
Expression System: E. coli
ctfB Protein, Clostridium acetobutylicum, Recombinant (His & Myc)
Cat.No: TMPH-00406
Species: Clostridium acetobutylicum
Expression System: E. coli
GH Protein, Rhesus macaque, Recombinant (His & Myc)
Cat.No: TMPH-02447
Species: Rhesus
Expression System: E. coli
GH Protein, Pig, Recombinant (His & Myc)
Cat.No: TMPH-03127
Species: Sus scrofa (Pig)
Expression System: E. coli
GH2 Protein, Human, Recombinant (His)
Cat.No: TMPZ-00002
Species: Human
Expression System: HEK294 Cells
MARCO Protein, Human, Recombinant (His)
Cat.No: TMPK-01228
Species: Human
Expression System: HEK293 Cells
Langerin/CD207 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02611
Species: Mouse
Expression System: E. coli
Transferrin Receptor/TFRC Protein, Human, Recombinant (aa 101-760, His)
Cat.No: TMPJ-00378
Species: Human
Expression System: HEK293 Cells
Single-strand DNA-binding protein Protein, Agrobacterium fabrum, Recombinant (His & Myc)
Cat.No: TMPH-00039
Species: Agrobacterium fabrum
Expression System: E. coli
Ferritin heavy chain 1/FTH1 Protein, Human, Recombinant
Cat.No: TMPY-02711
Species: Human
Expression System: E. coli
KRT18 Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-01577
Species: Human
Expression System: E. coli
Growth Hormone Protein, Mouse, Recombinant
Cat.No: TMPJ-00795
Species: Mouse
Expression System: E. coli
SLC17A6 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03400
Species: Rat
Expression System: P. pastoris (Yeast)
CPT2 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01050
Species: Human
Expression System: E. coli
NPTX1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01130
Species: Human
Expression System: HEK293 Cells
IGFBP-1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00811
Species: Human
Expression System: HEK293 Cells
FOLR1 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00150
Species: Human
Expression System: HEK293 Cells
Apolipoprotein E/APOE3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00756
Species: Human
Expression System: HEK293 Cells
FTH Protein, Human, Recombinant (His)
Cat.No: TMPJ-00761
Species: Human
Expression System: E. coli
PTX3 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00981
Species: Mouse
Expression System: HEK293 Cells
PRSS2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01580
Species: Mouse
Expression System: HEK293 Cells
--------- 更多 ---------
Cat. No. Product Name Target Signaling Pathways
T23983 Deutetrabenazine metabolite M4

SD-1018,Deuterated monohydroxy tetrabenazine,D6-tetrabenazine metabolite M4

Deutetrabenazine metabolite M4 is believed to be related to its effect as a reversible depletion of monoamines from nerve terminals. The major circulating metabolites of Deutetrabenazine, are reversible inhibitors of VMAT2, resulting in decreased uptake
TMID-0042 rac-Paroxetine-d4 Hydrochloride

rac-Paroxetine-d4 Hydrochloride 是 rac-Paroxetine Hydrochloride 的氘代化合物。rac-Paroxetine Hydrochloride 的 CAS 号为 78246-49-8。Paroxetine hydrochloride 是一种血清素摄取抑制剂,能抑制 GRK2 活性,IC50值为 14 μM。它可研究抑郁症。
TMIJ-0118 Paroxetine-d4 HCl

Paroxetine-d4 HCl 是 Paroxetine HCl 的氘代化合物。Paroxetine HCl 的 CAS 号为 78246-49-8。Paroxetine hydrochloride 是一种血清素摄取抑制剂,能抑制 GRK2 活性,IC50值为 14 μM。它可研究抑郁症。
TMID-0299 Zonisamide-d4

Zonisamide-d4 是 Zonisamide 的氘代化合物。Zonisamide 的 CAS 号为 68291-97-4。Zonisamide 是锌酶碳酸酐酶 (carbonic anhydrase) 的有效抑制剂,对人类线粒体同工酶 hCA II 和 hCA V 作用的Ki值分别为 35.2 nM 和 20.6 nM。Zonisamide 具有抗癫痫活性,在癫痫、癫痫发作和帕金森病的研究中具有价值。
TMID-0307 Sertraline-d3 Hydrochloride

Sertraline-d3 Hydrochloride 是 Sertraline Hydrochloride 的氘代化合物。Sertraline Hydrochloride 的 CAS 号为 79559-97-0。Sertraline hydrochloride 是选择性 5- 羟色胺再吸收抑制剂类的抗抑郁剂,可用于多种疾病的研究,如重度抑郁症和强迫症。
T71981 Gliclazide-d4

Gliclazide-d4 is intended for use as an internal standard for the quantification of gliclazide by GC- or LC-MS. Gliclazide is a sulfonylurea and an inhibitor of pancreatic β-cell ATP-sensitive potassium (KATP) channels. It is selective for pancreatic β-cell over cardiac and arterial smooth muscle cell KATP channels. Gliclazide (5 μM) increases insulin-induced glucose uptake and glucose transporter 4 (GLUT4) translocation to the plasma membrane in a differentiated 3T3L1 adipocyte model of insulin...
T73711 Atomoxetine-d3 hydrochloride

Atomoxetine-d3 hydrochloride 是氘代标记的Atomoxetine hydrochloride。Atomoxetine hydrochloride 是去甲肾上腺素重吸收抑制剂,与人NET,SERT 和DAT 的放射性配体结合的 Ki 分别为5,77和1451 nM。
T71302 Norfluoxetine-d5 HCl

Norfluoxetine-d5 is intended for use as an internal standard for the quantification of norfluoxetine by GC- or LC-MS. Norfluoxetine is an active metabolite of the antidepressant fluoxetine. It is formed from fluoxetine by the cytochrome P450 (CYP) isoforms CYP2C9, CYP2C19, and CYP3A. Norfluoxetine inhibits serotonin (5-HT) uptake in rat brain synaptosomal membrane preparations (Ki = 44.7 nM) and isolated human platelets (IC50 = ~15 nM). It has been found in the tissues of fish exposed to wastewa...
TMIJ-0157 Cefoperazone-d5

Cefoperazone-d5 是 Cefoperazone 的氘代化合物。Cefoperazone 的 CAS 号为 62893-19-0。Cefoperazone是一种半合成的头孢菌素,有抗菌活性。
TMIH-0582 Trazodone-d8 hydrochloride

Trazodone-d8 hydrochloride 是 Trazodone hydrochloride 的氘代化合物。Trazodone hydrochloride 的 CAS 号为 25332-39-2。Trazodone hydrochloride 是5 羟色胺受体拮抗剂和重吸收抑制剂,用作抗抑郁药,可治疗失眠和焦虑。
TMIH-0205 Duloxetine-d3 HCl

Duloxetine-d3 HCl 是 Duloxetine HCl 的氘代化合物。Duloxetine HCl 的 CAS 号为 136434-34-9。Duloxetine hydrochloride 是一种 5-羟色胺-去甲肾上腺素重吸收 (serotonin-norepinephrine reuptake) 抑制剂 (SNRI),Ki=4.6 nM,可用于广泛性焦虑症的研究。
TMID-0178 Stearic acid-18,18,18-d3

Stearic acid-18,18,18-d3 是 Stearic acid 的氘代化合物。Stearic acid 的 CAS 号为 57-11-4。Stearic acid是长链饱和脂肪酸,存在于许多动植物油脂中。
TMIH-0184 Desipramine-d3 HCl

Desipramine-d3 HCl 是 Desipramine HCl 的氘代化合物。Desipramine HCl 的 CAS 号为 58-28-6。Desipramine hydrochloride 是一种二苯并氮杂类衍生物三环类抗抑郁药,可作为选择性去甲肾上腺素再摄取抑制剂。 它还显示出较弱的 5-羟色胺再摄取抑制、α1 阻断、抗组胺和抗胆碱能作用。
TMID-0075 Reserpine-d9

Reserpine-d9 是 Reserpine 的氘代化合物。Reserpine 的 CAS 号为 50-55-5。Reserpine 是一种从催吐萝芙木的根中发现的生物碱。它抑制去甲肾上腺素吸收到储存囊泡中,导致中枢和外周轴突末端的儿茶酚胺和血清素耗尽。它可作为抗高血压药和抗精神病药以及研究工具。

同位素标记化合物

Deutetrabenazine metabolite M4
Cat.No: T23983
Synonym: SD-1018,Deuterated monohydroxy tetrabenazine,D6-tetrabenazine metabolite M4
Target:
rac-Paroxetine-d4 Hydrochloride
Cat.No: TMID-0042
Synonym:
Target:
Paroxetine-d4 HCl
Cat.No: TMIJ-0118
Synonym:
Target:
Zonisamide-d4
Cat.No: TMID-0299
Synonym:
Target:
Sertraline-d3 Hydrochloride
Cat.No: TMID-0307
Synonym:
Target:
Gliclazide-d4
Cat.No: T71981
Synonym:
Target:
Atomoxetine-d3 hydrochloride
Cat.No: T73711
Synonym:
Target:
Norfluoxetine-d5 HCl
Cat.No: T71302
Synonym:
Target:
Cefoperazone-d5
Cat.No: TMIJ-0157
Synonym:
Target:
Trazodone-d8 hydrochloride
Cat.No: TMIH-0582
Synonym:
Target:
Duloxetine-d3 HCl
Cat.No: TMIH-0205
Synonym:
Target:
Stearic acid-18,18,18-d3
Cat.No: TMID-0178
Synonym:
Target:
Desipramine-d3 HCl
Cat.No: TMIH-0184
Synonym:
Target:
Reserpine-d9
Cat.No: TMID-0075
Synonym:
Target:
共309条,每页50条 1 2 3 4 5 6 7
TargetMol Loading
联系我们
400-820-0310

上海市静安区江场三路238号8楼