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Targets Recommended: Monoamine Transporter Monocarboxylate transporter Na-K-Cl cotransporter transporter Serotonin Transporter Others

342

抑制剂 & 化合物

34

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化合物库

78

重组蛋白

13

同位素标记化合物

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Cat. No. Product Name
L2550 谷氨酰胺代谢化合物库

565 compounds
565 种谷氨酰胺代谢相关的分子,可以用于高通量和高内涵筛选;

化合物库

谷氨酰胺代谢化合物库
Cat.No: L2550
Compounds: 565
Cat. No. Product Name Target Signaling Pathways
T22714 Decynium 22

Others Others
Decynium 22 是有机阳离子转运蛋白和单胺转运蛋白的抑制剂,具有抗抑郁作用。
T9558 KL-11743

transporter Metabolism
KL-11743 是葡萄糖竞争性 I 类葡萄糖转运蛋白抑制剂,口服有活性,能够抑制GLUT1 (IC50:115 nM) 、GLUT2 (IC50:137 nM) 、GLUT3 (IC50:90 nM) 及GLUT4 (IC50:68 nM) 。它能够特异性阻断葡萄糖代谢,也可与电子传递抑制剂协同作用诱导细胞死亡。
T3713 BAY-876

transporter Metabolism
BAY-876 是口服有效的,选择性的葡萄糖转运蛋白 1 (GLUT1) 抑制剂(IC50= 2 nM)。BAY-876 对 GLUT1 选择性比 GLUT2,GLUT3 和 GLUT4 高(>130 倍)。BAY-876 对糖酵解代谢和卵巢癌生长也有有效的抑制作用。
T7147 Valbenazine

NBI-98854

Monoamine Transporter Membrane transporter/Ion channel
Valbenazine (NBI-98854) 是一种高度选择性的囊泡单胺转运蛋白 2 (VMAT2) 抑制剂,Ki 为 110-190 nM,用于治疗迟发性运动障碍。
T23070 Nisoxetine hydrochloride

Sodium Channel; Monoamine Transporter; Norepinephrine Membrane transporter/Ion channel; Neuroscience
Nisoxetine hydrochloride 是一种去甲肾上腺素转运蛋白 (NET) 抑制剂,Kd 值为 0.76 nM。它是抗抑郁药和局部麻药,可以阻断电压门控性钠通道。
T9347 EAAT2 activator 1

3-[(2-Chloro-6-fluorobenzyl)thio]-6-pyridin-2-ylpyridazine

transporter Metabolism
EAAT2 activator 1 (3-[(2-Chloro-6-fluorobenzyl)thio]-6-pyridin-2-ylpyridazine) 是兴奋性氨基酸转运蛋白 2(EAAT2) 的有效激活剂,以剂量依赖性方式增加 EAAT2 蛋白水平。
T7341 Diclofensine

Ro 8-4650

Dopamine Receptor; 5-HT Receptor; Monoamine Transporter GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
Diclofensine (Ro 8-4650) 是一种单胺再摄取抑制剂,在大鼠脑突触体中能够阻断多巴胺 (IC50=0.74 nM)、去甲肾上腺素 (IC50=2.3 nM) 和 5-羟色胺 (IC50=3.7 nM)。
T11087 DOV-216,303 Free Base

DOV-216303

Dopamine Receptor; Serotonin Transporter; Norepinephrine GPCR/G Protein; Neuroscience
DOV-216,303 Free Base (DOV-216303) 是血清素、去甲肾上腺素和多巴胺再摄取的抑制剂,IC50 为 14、20 和 78 nM。 DOV-216,303 Free Base 具有抗抑郁作用。
T39429 AHN 1-055 hydrochloride

3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride

Dopamine Receptor GPCR/G Protein; Neuroscience
AHN 1-055 hydrochloride (3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride) 与多巴胺转运蛋白具有高亲和力,是多巴胺摄取抑制剂,IC50为 71 nM。
T8708 Paroxetine

Serotonin Transporter Neuroscience
Paroxetine 是选择性血清素再摄取抑制剂,是苯基哌啶的衍生物。 它对于甲肾上腺素摄取抑制功能较弱,但比该位点其他SSRIs 更有效。
T7018 WZB117

transporter Metabolism
WZB117 是葡萄糖转运蛋白 1 抑制剂,可下调糖酵解,诱导细胞周期停滞,有抗癌细胞生长的作用。
T15160 Dotinurad

(3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone

OAT Membrane transporter/Ion channel
Dotinurad ((3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone) 是有效的尿酸盐重吸收选择性抑制剂,抑制尿酸盐转运蛋白 1的IC50为 37.2 nM,具有促尿酸排泄的作用。
T12232 Nitroxazepine

CIBA 2330Go

Serotonin Transporter Neuroscience
Nitroxazepine (CIBA 2330Go) 是三环抗抑郁化合物,是一种 5-羟色胺去甲肾上腺素再摄取抑制剂,可用于抗抑郁的研究。
T5208 BAY-8002

BAY8002,BAY 8002

Monocarboxylate transporter Membrane transporter/Ion channel
BAY-8002 是一种可口服的单羧酸转运蛋白第 1 亚型 MCT1 选择性抑制剂,在表达 MCT1 的 DLD-1 细胞中,IC50值为 85 nM,具有抗肿瘤活性。
T1768 7ACC2

Mitochondrial Metabolism; Monocarboxylate transporter Membrane transporter/Ion channel; Metabolism
7ACC2 是单羧酸盐转运蛋白抑制剂,IC50为 11 nM。它还是线粒体丙酮酸转运的有效抑制剂,可抑制乳酸涌入,通过抑制乳酸通量来发挥抗癌作用。
T10758L Centanafadine hydrochloride

EB-1020 hydrochloride

Dopamine Receptor; Serotonin Transporter; Adrenergic Receptor; Norepinephrine GPCR/G Protein; Neuroscience
Centanafadine hydrochloride (EB-1020 hydrochloride) 是一种去甲肾上腺素(NE)/多巴胺(DA)转运的双抑制剂,还能抑制5-羟色胺(serotonin)转运体。它对人 NE,DA 和5-羟色胺转运体的 IC50值分别为6 nM,38 nM 和 83 nM。
T3526 Dasotraline hydrochloride

SEP-225289 hydrochloride,达索曲林盐酸盐

Dopamine Receptor; 5-HT Receptor; Serotonin Transporter; Norepinephrine GPCR/G Protein; Neuroscience
Dasotraline hydrochloride (SEP-225289 hydrochloride) 是具有阻断多巴胺 (IC50=4 nM),去甲肾上腺素 (IC50=6 nM) 和三羟色胺转运蛋白 (IC50=11 nM)的三重再摄取抑制剂。
T3210 AZD3965

AZD 3965,AZD-3965

Monocarboxylate transporter Membrane transporter/Ion channel
AZD3965 (AZD-3965) 是单羧酸转运蛋白 1 (MCT1) 的选择性抑制剂,Ki 值为1.6 nM,比 MCT2的选择性高6倍。
T15411 GPNA hydrochloride

Apoptosis; Others Apoptosis; Others
GPNA hydrochloride 是一种 γ-谷氨酰转移酶的知名底物,可逆地诱导 A549 细胞凋亡。它是一种特定的谷氨酰胺转运蛋白ASCT2抑制剂,还抑制依赖 Na+的载体,如 SNAT 家族 (SNAT1/2/4/5) 和不依赖 Na+的亮氨酸转运蛋白 LAT1/2。
T14316 AR-C155858

Monocarboxylate transporter Membrane transporter/Ion channel
AR-C155858 是单羧酸转运蛋白 MCT1 和 MCT2 的抑制剂,Ki 分别为2.3和 10 nM。
T11064 DMT1 blocker 2

Others Others
DMT1 blocker 2 是一种二价金属转运蛋白 1 的直接抑制剂(IC50:0.83 μM)。它可以阻断体内肠细胞的铁摄取。
T0322 Fipexide

Dopamine Receptor; AChR GPCR/G Protein; Neuroscience
Fipexide 是对氯苯乙酸衍生物,是哌嗪化学类的精神活性药物,作为促智药物,有用于老年痴呆的研究潜力。它可降低了纹状体腺苷酸环化酶的活性,通过多巴胺能神经传递对认知表现出积极的作用。
T2363 STF-31

transporter; Autophagy Autophagy; Metabolism
STF31 是一种葡萄糖转运蛋白 1 的选择性抑制剂,IC50为 1 μM。
T8732 CTPI-2

Others; Mitochondrial Metabolism Metabolism; Others
CTPI-2 是一种特异性线粒体柠檬酸盐载体SLC25A1抑制剂,KD=3.5 μM,具有抗肿瘤作用。它能够抑制糖酵解、PPARγ 及其下游靶点葡萄糖转运蛋白 GLUT4。它阻断非酒精性脂肪性肝炎逆转脂肪变性的显著改变,防止演变为脂肪性肝炎,减少肝脏和脂肪组织中炎性巨噬细胞的浸润,并显著减轻由高脂肪饮食引起的肥胖。
T2092 Amitifadine hydrochloride

DOV-21947 hydrochloride,EB-1010 hydrochloride

Dopamine Receptor; 5-HT Receptor; Serotonin Transporter; Norepinephrine GPCR/G Protein; Neuroscience
Amitifadine hydrochloride (EB-1010 hydrochloride) 是一种 5-羟色胺-去甲肾上腺素-多巴胺的再摄取抑制剂(SNDRI),其在 HEK 293 细胞中测得的 IC50值分别为 12, 23, 96 nM。
T5345 V-9302

Others Others
V-9302 是一种跨膜谷氨酰胺通量的竞争性拮抗剂。它选择性的靶向氨基酸转运体 ASCT2 (SLC1A5),不影响 ASCT1。它能够阻碍 HEK-293 细胞中由 ASCT2 介导的谷氨酰胺摄取 (IC50=9.6 μM)。
T3994 Verinurad

RDEA3170,维立诺雷

OAT Membrane transporter/Ion channel
Verinurad (RDEA3170) 是一种有效的、特异性的URAT1抑制剂,IC50为 25 nM。
T6414 Bisacodyl

比沙可啶,Fenilaxan,Dulcolax,Brocalax

Others Others
Bisacodyl (Fenilaxan) 是刺激性缓泻剂,可直接作用于结肠以产生排便。它能够直接激活结肠巨噬细胞来增加 PGE2的分泌。PGE2充当旁分泌因子并减少结肠中 AQP3 的表达,抑制水从腔向血管一侧的转移,进而产生通便作用。
T7061 Duloxetine

Serotonin Transporter Neuroscience
Duloxetine 是一种 5 羟色胺-去甲肾上腺素重吸收 (serotonin-norepinephrine reuptake) 抑制剂,Ki=4.6 nM,可作用于广泛性焦虑症的研究。
T15728 LDN-212320

LDN-0212320,LDN/OSU-0212320,OSU-0212320

transporter Metabolism
LDN-212320 (OSU-0212320) 是兴奋性氨基酸转运体 2(EAAT2)/谷氨酸转运体(GLT-1)的激活剂。它通过上调海马和 ACC 星形胶质细胞 GLT-1 的水平来预防伤害性疼痛。
T4182 lavendustin B

薰草菌素B

Tyrosinase; transporter; HIV Protease Metabolism; Microbiology/Virology; Proteases/Proteasome
Lavendustin B 是一种酪氨酸激酶抑制剂,是 HIV-1 整合酶 (IN) 与其同源细胞辅助因子、晶状体上皮衍生生长因子 (LEDGF/p75) 相互作用的抑制剂。
T6875 Lesinurad

RDEA594,雷西那德,来司诺雷

OAT Membrane transporter/Ion channel
Lesinurad (RDEA594) 是URAT1和OAT 抑制剂。Lesinurad 用作肾转运蛋白OAT1 和OAT3 的底物,Km 分别为 0.85 和 2 μM。
T8551 Nitrobenzylthioinosine

NBMPR,S-(4-硝基苄基)-6-硫代肌苷

AChR; Adenosine Receptor GPCR/G Protein; Neuroscience
Nitrobenzylthioinosine (NBMPR) 是一种 ENT1 转运蛋白抑制剂,可与 ENT1 转运蛋白以高亲和力结合。它是一种可穿过血脑屏障的光亲和探针,用于追踪大脑中腺苷的摄取位点。
T20545 Benzarone

Benzarona,Vasoc,苯扎隆,Venagil,Benzaronum

OAT Membrane transporter/Ion channel
Benzarone (Benzarona) 是人尿酸转运蛋白 1的有效抑制剂,IC50为 2.8 μM。它具有降低血清尿酸水平的作用。
T0450 Fluoxetine

氟西汀,LY-110140

5-HT Receptor; Serotonin Transporter; MRP; Autophagy Autophagy; GPCR/G Protein; Immunology/Inflammation; Neuroscience
Fluoxetine (LY-110140) 是一种高度特异性的血清素摄取抑制剂,是选择性 5-羟色胺 (5-HT) 再吸收抑制剂。Fluoxetine 具有抗抑郁活性。
T0719 Tetrabenazine

Xenazine,丁苯那嗪,Ro 1-9569

Others; Dopamine Receptor; Monoamine Transporter GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience; Others
Tetrabenazine (Ro 1-9569) 是 VMAT 抑制剂,用作抗精神病药和治疗各种运动障碍。
T0413 Cinromide

醒隆酰胺,trans-3-Bromo-N-ethylcinnamamide

Others Others
Cinromide (trans-3-Bromo-N-ethylcinnamamide) 是抗惊厥药,能够抑制上皮中性氨基酸转运蛋白 B0AT1 (SLC6A19),其 IC50=0.5 μM。
T6697 TCID

UCH-L3 Inhibitor

DUB Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination
TCID (UCH-L3 Inhibitor) 是一种有效的选择性神经元泛素 C 末端水解酶 L3 的 DUB 抑制剂,IC50为 0.6 μM。它对 L1 具有 125 倍的选择性,可减少脑干和脊髓原代神经元中的甘氨酸转运蛋白 GlyT2 泛素化。
T1189 Milnacipran hydrochloride

盐酸米那普仑,Milnacipran HCl,Savella,Dalcipran

Serotonin Transporter; Norepinephrine Neuroscience
Milnacipran hydrochloride (Savella) 是一种5-羟色胺-去甲肾上腺素重吸收抑制剂(SNRI),可用于纤维肌痛的研究。
T2594 Dextromilnacipran

Levomilnacipran,左旋米那普仑

Serotonin Transporter; Norepinephrine Neuroscience
Dextromilnacipran (Levomilnacipran) 是米那普仑的对映体,是一种选择性 5- 羟色胺和去甲肾上腺素(5-HT/NE)再摄取抑制剂,也是一种人类 α 肾上腺素能受体拮抗剂,IC50=3.4 μM。
T0991 Desipramine hydrochloride

NSC-114901,Desmethylimipramine,盐酸去甲咪嗪,JB-8181,EX-4355,Norimipramine,G-35020

Dopamine Receptor; 5-HT Receptor; Serotonin Transporter; Adrenergic Receptor GPCR/G Protein; Neuroscience
Desipramine hydrochloride (Norimipramine) 是一种二苯并氮杂类衍生物三环类抗抑郁药,可作为选择性去甲肾上腺素再摄取抑制剂。 它还显示出较弱的 5-羟色胺再摄取抑制、α1 阻断、抗组胺和抗胆碱能作用。
T22453 Venlafaxine

Wy 45030,文拉法辛

Serotonin Transporter Neuroscience
Venlafaxine (Wy 45030) 是一种口服有效的 5-羟色胺 (5-HT)/去甲肾上腺素 (NE) 重摄取的双重抑制剂,具有抗抑郁活性。
T0766 Promazine hydrochloride

Romtiazin hydrochloride,Sinophenin hydrochloride,盐酸丙嗪

Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; AChR GPCR/G Protein; Neuroscience
Promazine hydrochloride (Romtiazin hydrochloride) 是一种抗精神病药,也是一种多巴胺受体 (D2) 拮抗剂,能够抑制多巴胺能神经传递。
T2556 Nandrolone decanoate

癸酸诺龙,19-Nortestosterone decanoate

Others; HIV Protease Microbiology/Virology; Others; Proteases/Proteasome
Nandrolone decanoate (19-Nortestosterone decanoate) 是一种合成代谢雄激素,通过涉及谷氨酸诱导的 N-甲基-D-天冬氨酸受体过度兴奋的机制诱导攻击性行为表征。
T1871 GBR 12935 dihydrochloride

GBR12935,GBR-12935,GBR 12935

Dopamine Receptor GPCR/G Protein; Neuroscience
GBR 12935 dihydrochloride (GBR 12935) 是一种多巴胺再吸收抑制剂。
T8616 Fasentin

N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide

transporter Metabolism
Fasentin (N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide) 是葡萄糖摄取抑制剂,可抑制GLUT-1/GLUT-4转运蛋白,优先抑制 GLUT4,IC50为 68 μM。它是死亡受体刺激敏化剂,可敏化细胞对 FAS 诱导的细胞死亡,具有抗血管生成活性。
T1993 J-147

J147

Epigenetic Reader Domain; Dopamine Receptor; Monoamine Oxidase Chromatin/Epigenetic; GPCR/G Protein; Neuroscience
J-147 是一种高效的、具有口服活性的、可透过血脑屏障神经保护剂,可增强认知能力。它抑制单胺氧化酶 B 和多巴胺转运体,EC50分别为 1.88 μM 和 0.649 μM。它有研究阿尔茨海默氏症的潜力。
T2227 Hemicholinium 3

半胆碱基-3,Hemicholinium-3,Hemicholine

Others; AChE Neuroscience; Others
Hemicholinium 3 是一种竞争性的、高亲和力的胆碱转运蛋白 (HACU) 抑制剂,Ki=25 nM。它是一种神经肌肉阻滞剂,能够抑制乙酰胆碱 (ACh)的合成和释放。它抑制Epibatidine 诱发的收缩和 [3H] 乙酰胆碱释放,IC50分别为 897 nM 和 693 nM。
T7460 α-Cyano-4-hydroxycinnamic acid

α-Cyano-4-hydroxycinnamic acid(α-CHCA),2-氰基-4-羟基

Monocarboxylate transporter Membrane transporter/Ion channel
α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamic acid(α-CHCA)) 是非竞争性单羧酸盐转运蛋白 (MCTs) 抑制剂,可抑制线粒体丙酮酸转运蛋白,Ki 值为 6.3 μM。它可作为基质辅助激光解吸电离-飞行时间质谱 (MALDI-TOF) 分析的基质,可以促进肽离子化。
T1580 Desvenlafaxine

去甲文拉法辛,WY 45233 Succinate,O-Desmethylvenlafaxine

5-HT Receptor; Serotonin Transporter; Norepinephrine GPCR/G Protein; Neuroscience
Desvenlafaxine (O-Desmethylvenlafaxine) 是 Venlafaxine 主要代谢物的丁二酸盐形式,在人多巴胺转运体上显示弱的结合亲和力。它是一种具有口服活性的、能透过血脑屏障的5-HT 和去甲肾上腺素再摄取的抑制剂,对 hSERT 和 hNET 的IC50值分别为 47.3 nM 和 531.3 nM。

化合物

Decynium 22
Cat.No: T22714
Synonym:
Target: Others
KL-11743
Cat.No: T9558
Synonym:
Target: transporter
BAY-876
Cat.No: T3713
Synonym:
Target: transporter
Valbenazine
Cat.No: T7147
Synonym: NBI-98854
Target: Monoamine Transporter
Nisoxetine hydrochloride
Cat.No: T23070
Synonym:
Target: Sodium Channel, Monoamine Transporter, Norepinephrine
EAAT2 activator 1
Cat.No: T9347
Synonym: 3-[(2-Chloro-6-fluorobenzyl)thio]-6-pyridin-2-ylpyridazine
Target: transporter
Diclofensine
Cat.No: T7341
Synonym: Ro 8-4650
Target: Dopamine Receptor, 5-HT Receptor, Monoamine Transporter
DOV-216,303 Free Base
Cat.No: T11087
Synonym: DOV-216303
Target: Dopamine Receptor, Serotonin Transporter, Norepinephrine
AHN 1-055 hydrochloride
Cat.No: T39429
Synonym: 3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride
Target: Dopamine Receptor
Paroxetine
Cat.No: T8708
Synonym:
Target: Serotonin Transporter
WZB117
Cat.No: T7018
Synonym:
Target: transporter
Dotinurad
Cat.No: T15160
Synonym: (3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone
Target: OAT
Nitroxazepine
Cat.No: T12232
Synonym: CIBA 2330Go
Target: Serotonin Transporter
BAY-8002
Cat.No: T5208
Synonym: BAY8002,BAY 8002
Target: Monocarboxylate transporter
7ACC2
Cat.No: T1768
Synonym:
Target: Mitochondrial Metabolism, Monocarboxylate transporter
Centanafadine hydrochloride
Cat.No: T10758L
Synonym: EB-1020 hydrochloride
Target: Dopamine Receptor, Serotonin Transporter, Adrenergic Receptor, Norepinephrine
Dasotraline hydrochloride
Cat.No: T3526
Synonym: SEP-225289 hydrochloride,达索曲林盐酸盐
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine
AZD3965
Cat.No: T3210
Synonym: AZD 3965,AZD-3965
Target: Monocarboxylate transporter
GPNA hydrochloride
Cat.No: T15411
Synonym:
Target: Apoptosis, Others
AR-C155858
Cat.No: T14316
Synonym:
Target: Monocarboxylate transporter
DMT1 blocker 2
Cat.No: T11064
Synonym:
Target: Others
Fipexide
Cat.No: T0322
Synonym:
Target: Dopamine Receptor, AChR
STF-31
Cat.No: T2363
Synonym:
Target: transporter, Autophagy
CTPI-2
Cat.No: T8732
Synonym:
Target: Others, Mitochondrial Metabolism
Amitifadine hydrochloride
Cat.No: T2092
Synonym: DOV-21947 hydrochloride,EB-1010 hydrochloride
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine
V-9302
Cat.No: T5345
Synonym:
Target: Others
Verinurad
Cat.No: T3994
Synonym: RDEA3170,维立诺雷
Target: OAT
Bisacodyl
Cat.No: T6414
Synonym: 比沙可啶,Fenilaxan,Dulcolax,Brocalax
Target: Others
Duloxetine
Cat.No: T7061
Synonym:
Target: Serotonin Transporter
LDN-212320
Cat.No: T15728
Synonym: LDN-0212320,LDN/OSU-0212320,OSU-0212320
Target: transporter
lavendustin B
Cat.No: T4182
Synonym: 薰草菌素B
Target: Tyrosinase, transporter, HIV Protease
Lesinurad
Cat.No: T6875
Synonym: RDEA594,雷西那德,来司诺雷
Target: OAT
Nitrobenzylthioinosine
Cat.No: T8551
Synonym: NBMPR,S-(4-硝基苄基)-6-硫代肌苷
Target: AChR, Adenosine Receptor
Benzarone
Cat.No: T20545
Synonym: Benzarona,Vasoc,苯扎隆,Venagil,Benzaronum
Target: OAT
Fluoxetine
Cat.No: T0450
Synonym: 氟西汀,LY-110140
Target: 5-HT Receptor, Serotonin Transporter, MRP, Autophagy
Tetrabenazine
Cat.No: T0719
Synonym: Xenazine,丁苯那嗪,Ro 1-9569
Target: Others, Dopamine Receptor, Monoamine Transporter
Cinromide
Cat.No: T0413
Synonym: 醒隆酰胺,trans-3-Bromo-N-ethylcinnamamide
Target: Others
TCID
Cat.No: T6697
Synonym: UCH-L3 Inhibitor
Target: DUB
Milnacipran hydrochloride
Cat.No: T1189
Synonym: 盐酸米那普仑,Milnacipran HCl,Savella,Dalcipran
Target: Serotonin Transporter, Norepinephrine
Dextromilnacipran
Cat.No: T2594
Synonym: Levomilnacipran,左旋米那普仑
Target: Serotonin Transporter, Norepinephrine
Desipramine hydrochloride
Cat.No: T0991
Synonym: NSC-114901,Desmethylimipramine,盐酸去甲咪嗪,JB-8181,EX-4355,Norimipramine,G-35020
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Adrenergic Receptor
Venlafaxine
Cat.No: T22453
Synonym: Wy 45030,文拉法辛
Target: Serotonin Transporter
Promazine hydrochloride
Cat.No: T0766
Synonym: Romtiazin hydrochloride,Sinophenin hydrochloride,盐酸丙嗪
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, AChR
Nandrolone decanoate
Cat.No: T2556
Synonym: 癸酸诺龙,19-Nortestosterone decanoate
Target: Others, HIV Protease
GBR 12935 dihydrochloride
Cat.No: T1871
Synonym: GBR12935,GBR-12935,GBR 12935
Target: Dopamine Receptor
Fasentin
Cat.No: T8616
Synonym: N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide
Target: transporter
J-147
Cat.No: T1993
Synonym: J147
Target: Epigenetic Reader Domain, Dopamine Receptor, Monoamine Oxidase
Hemicholinium 3
Cat.No: T2227
Synonym: 半胆碱基-3,Hemicholinium-3,Hemicholine
Target: Others, AChE
α-Cyano-4-hydroxycinnamic acid
Cat.No: T7460
Synonym: α-Cyano-4-hydroxycinnamic acid(α-CHCA),2-氰基-4-羟基
Target: Monocarboxylate transporter
Desvenlafaxine
Cat.No: T1580
Synonym: 去甲文拉法辛,WY 45233 Succinate,O-Desmethylvenlafaxine
Target: 5-HT Receptor, Serotonin Transporter, Norepinephrine
Cat. No. Product Name Target Signaling Pathways
TN6552 5,7-Dimethoxyluteolin

Dopamine Receptor GPCR/G Protein; Neuroscience
5,7-Dimethoxyluteolin 是 5,7-二甲基木犀草素的一种衍生物,可以活化多巴胺转运蛋白,EC50为 3.417 μM。
T0791 Reserpine

利血平,Serpalan,Serpasil,Serpivite

Others; Potassium Channel; MRP; Monoamine Transporter; Autophagy Autophagy; Immunology/Inflammation; Membrane transporter/Ion channel; Others
Reserpine (Serpalan) 是一种从催吐萝芙木的根中发现的生物碱。它抑制去甲肾上腺素吸收到储存囊泡中,导致中枢和外周轴突末端的儿茶酚胺和血清素耗尽。它可作为抗高血压药和抗精神病药以及研究工具。
TN2252 Syrosingopine

Dopamine Receptor GPCR/G Protein; Neuroscience
Syrosingopine 是 MCT1和 MCT4双重抑制剂,对 MCT4 的效力高 60 倍,可防止乳酸和 H+ 流出。它是可口服抗高血压药物,联合二甲双胍具有研究癌症疾病的潜力。
TN1118 Tormentic acid

2Α,19Α-二羟基熊果酸,委陵菜酸

Immunology/Inflammation related Immunology/Inflammation
Tormentic acid 是一种分离自 Rosa rugosa 中的三萜,具有抗炎、降血脂和抗动脉粥样硬化活性。
T4S1545 Licarin B

(-)-Licarin B,Licarine B,(-)-利卡灵B

transporter; Antibacterial; PPAR DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
Licarin B (Licarine B) 是来源于肉豆蔻种子的一种天然产物,是 NO 生成抑制剂,可通过激活 IRS-1/PI3K/AKT 通路中的PPARγ和GLUT4 改善胰岛素敏感性。
T7521 Azaphen

Pipofezin hydrochloride,阿扎吩,Pipofezine hydrochloride,Azafen

5-HT Receptor; Serotonin Transporter GPCR/G Protein; Neuroscience
Azaphen (Pipofezin hydrochloride) 是一种 5-羟色胺重吸收抑制剂。
T1317 Cinchonidine

奎宁树,α-Quinidine,辛可尼丁,L-Cinchonidine

5-HT Receptor; Serotonin Transporter; Parasite GPCR/G Protein; Microbiology/Virology; Neuroscience
Cinchonidine (L-Cinchonidine) 是在金鸡纳和角蒿中发现的一种生物碱,有抗疟活性。 它是用于有机化学中不对称合成的砌块,是血清素转运蛋白的弱抑制剂。
T3S0364 L-Arginine

L-精氨酸,L-Arg,(S)-(+)-Arginine

IL Receptor; Endogenous Metabolite; NO Synthase Immunology/Inflammation; Metabolism
L-Arginine (L-Arg) 是内皮型一氧化氮合酶(eNOS) 的底物。L-Arginine 通过阳离子氨基酸转运体家族转运到血管平滑肌细胞,并被代谢成一氧化氮、多胺或 L-脯氨酸。
T2203 D-Carnitine hydrochloride

(S)-Carnitine Hydrochloride,L-Carnitine hydrochloride

Others; Endogenous Metabolite Metabolism; Others
D-Carnitine hydrochloride ((S)-Carnitine Hydrochloride) 已被用于研究麦角硫因素转运蛋白 SLC22A4 和肉毒碱转运蛋白 SLC22A5,也被用于使棕榈酸进入线粒体。
T0185 Escitalopram

Seroplex,依他普仑,S-(+)-Citalopram,艾司西酞普兰,(S)-Citalopram

Dopamine Receptor; 5-HT Receptor; Serotonin Transporter; Adrenergic Receptor; AChR; Norepinephrine; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Escitalopram (Seroplex) 是一种外消旋 Citalopram 的 S-对映体,是一种选择性 5-羟色胺再摄取抑制剂,Ki=0.89 nM,比 R(-)-enantiomer 结合亲和力高 30 倍。它对多巴胺转运体和去甲肾上腺素转运体均有选择性,是一种研究抑郁症的抗抑郁药。
T2924 Phloretin

根皮素,Dihydronaringenin,NSC 407292,RJC 02792

SGLT; transporter; Endogenous Metabolite GPCR/G Protein; Metabolism
Phloretin (NSC-407292) 是从苹果树叶中提取的一种查耳酮,具有抗炎、抗氧化和抗癌活性。它是真核尿素转运蛋白抑制剂,可阻断 VacA 介导的尿素和离子转运,有潜力用于类风湿性关节炎和过敏性气道炎症的相关研究。
T6S0117 Avicularin

Fenicularin,扁蓄苷

ERK MAPK
Avicularin (Fenicularin) 具有抗过敏、抗炎、保肝、抗氧化、抗肿瘤等活性。它能通过调节 NF-κB(p65)、COX-2 和 PPAR-γ 的活性来改善人类肝细胞癌。在 LPS 刺激的 RAW 264.7 巨噬细胞中,它通过抑制 ERK 信号通路产生抗炎活性。
TN1033 Sennidin A

HCV Protease; transporter; Akt; PI3K Cytoskeletal Signaling; Metabolism; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
Sennidin A 是从狭叶番泻分离得到的一种天然产物,能够抑制 HCV NS3 解旋酶,其 IC50值为0.8 μM。它诱导 Akt 和葡萄糖转运蛋白4的磷酸化,刺激葡萄糖掺入。
TN1034 Sennidin B

HCV Protease; transporter; Akt; PI3K Cytoskeletal Signaling; Metabolism; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
Sennidin B 是从Cassia angustifolia 分离得到的Sennidin A 异构体,它刺激葡萄糖掺入,诱导Akt 和葡萄糖转运蛋白4 的磷酸化。
T2755 Rhoifolin

野漆树苷,Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside

Others; p38 MAPK; NF-κB; transporter; IGF-1R; Autophagy Autophagy; MAPK; Metabolism; NF-κB; Others; Tyrosine Kinase/Adaptors
Rhoifolin (Apigenin 7-O-neohesperidoside) 是从琯溪蜜柚叶子分离的一种黄酮糖苷。它通过 RANKL 诱导的NF-κB 和MAPK 途径改善钛颗粒刺激的骨溶解并减少破骨细胞生成。它通过增强脂联素分泌,胰岛素受体-β的酪氨酸磷酸化和GLUT4易位有助于治疗糖尿病并发症。
T19866 Indican

NSC-87517,3-Indoxyl-beta-D-glucopyranoside,3-吲哚基-beta-D-吡喃葡萄糖苷,NSC 87517,NSC87517,Indoxyl-β-D-glucoside

OAT; MRP Immunology/Inflammation; Membrane transporter/Ion channel
Indican (Indoxyl-β-D-glucoside) 是吲哚酚的一种糖苷,染料靛蓝和靛玉红的前体。它的主要代谢物是硫酸吲哚酚 (IS)。其中 IS 是尿毒症毒素,是有机阴离子转运蛋白1 (OAT 1)、OAT 3 和多药耐药相关蛋白4 (MRP 4) 的底物/抑制剂。
T4702 (3-Carboxypropyl)trimethylammonium chloride

γ-Butyrobetaine hydrochloride,(3-羧丙基)三甲基氯化铵,(3-Carboxypropyl)trimethylammonium chlor

Endogenous Metabolite Metabolism
(3-Carboxypropyl)trimethylammonium chloride ((3-Carboxypropyl)trimethylammonium chlor) 一种血管病变性中间代谢物,是由肠道微生物代谢产生,这些微生物以红肉中的肉碱为食。
TN5118 Taxol C

P-gp Membrane transporter/Ion channel; Neuroscience
Taxol C 可以减少与 P-糖蛋白转运蛋白的相互作用,从而增加紫杉烷类向大脑的渗透。
T4912 Jatrorrhizine chloride

盐酸药根碱,Yatrorhizine chloride,Neprotine chloride

Others; 5-HT Receptor; OCT; Antibacterial; AChE GPCR/G Protein; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; Others
Jatrorrhizine chloride (Neprotine chloride) 是从黄连中分离得到的生物碱,具有神经保护、抗菌、抗氧化和抗疟原虫活性。它通过抑制摄取2转运蛋白的活性减少血清素和去甲肾上腺素的摄取。它是具有口服活性的乙酰胆碱酯酶抑制剂。
T6975 Sarcosine

Sarcosinic acid,Methylaminoacetic acid,Sarcosin,肌氨酸,Methylglycine,N-Methylaminoacetic acid,N-methylglycine

Others; GlyT; Endogenous Metabolite Metabolism; Neuroscience; Others
Sarcosine (Methylglycine) 是 I 型甘氨酸转运蛋白 (GlyT1) 的竞争性抑制剂和 N-甲基-D-天冬氨酸受体 (NMDAR) 共激动剂,通过增加甘氨酸的浓度增强 NMDA 受体的功能,可用于精神分裂症的研究。
T1153 Trimethoprim

NIH 204,BW 56-72,甲氧苄啶,NSC-106568

DHFR; DNA/RNA Synthesis; Antifolate; Antibacterial; Antibiotic Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
Trimethoprim (NSC-106568) 是抑菌抗生素,也是具有口服活性的二氢叶酸还原酶抑制剂。它对多种革兰氏阳性和革兰氏阴性需氧细菌具有活性,可用于尿路感染,肺孢子菌肺炎和志贺氏菌病的研究。
T13655 DL-Norepinephrine hydrochloride

去甲肾上腺素盐酸盐,Lys,DL-lysine

Adrenergic Receptor GPCR/G Protein; Neuroscience
DL-Norepinephrine hydrochloride (DL-lysine) 是一种靶向α1 adrenoceptor 和β1 adrenoceptor 的神经递质,可降低心内膜下氧分压。它是一种模拟内源性去甲肾上腺素的拟交感神经作用的合成苯乙胺。
T4S0779 D-tetrahydropalmatine

Others; Dopamine Receptor GPCR/G Protein; Neuroscience; Others
D-Tetrahydropalmatine 是一种主要存在于延胡索类植物中的异喹啉生物碱。它是有机阳离子转运蛋白 1 抑制剂。它是多巴胺受体拮抗剂,对 D1 受体具有优先亲和力。
T3933 Jatrorrhizine

Yatrorizine,neprotin,药根碱

MAO; 5-HT Receptor; Antibacterial; AChE GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience
Jatrorrhizine (neprotin) 是一种从黄连中分离得到的生物碱,具有抗菌、抗氧化、抗疟原虫和神经保护活性。它通过抑制 uptake-2 transporter 的活性减少血清素和去甲肾上腺素的摄取。它是一种有口服活性的乙酰胆碱酯酶制剂。
T19772 Mesembrenone

(+)-Mesembrenone

Others Others
Mesembrenone is a selective the serotonin transporter (SERT) inhibitor. Mesembrenone is the main alkaloid of Sceletium tortuosum.
T72961 Falcarindiol

法卡林二醇

Others Others
Falcarindiol 是一种口服活性聚乙炔氧脂,能激活 PPARγ 并增加 ABCA1 表达,具有诱导细胞凋亡和自噬的功能。此外,Falcarindiol 还展现出抗炎、抗菌、抗癌和抗糖尿病等特性。
T80013 Arecaidine hydrobromide

GABA Receptor Membrane transporter/Ion channel; Neuroscience
Arecaidine hydrobromide,一种吡啶生物碱,有效抑制GABA吸收。作为H+偶联的氨基酸转运蛋白1(PAT1,SLC36A1)的底物,它竞争性地抑制L-脯氨酸的摄取。
T72172 4,6-O-Ethylidene-α-D-glucose

Ethylidene-glucose

Others Others
4,6-O-ethylidene-α-D-glucose (Ethylidene-glucose) 是一种葡萄糖衍生物,是竞争性的葡萄糖转运蛋白 1 (GLUT1) 面部结合部位抑制剂,对野生型 2-脱氧-D-葡萄糖转运的 Ki 值为 12 mM。
T72645 Norbatzelladine L

Others Others
Norbatzelladine L 是一种 Pdr5p 转运蛋白催化活性和功能活性的抑制剂。Norbatzelladine L 抑制 Pdr5p ATPase 活性,IC50值为 3.8 µM。Norbatzelladine L 具有抗真菌 (antifungal)、抗寄生虫 (antiparasitic)、抗病毒 (antiviral)、抗细菌 (antibacterial) 和抗肿瘤活性。
T73857 Mesembrine

Others Others
Mesembrine ((+)-Mesembrine) 一种主要的生物碱,具有芳基八氢吲哚骨架。Mesembrine 是一种5-HT 转运蛋白抑制剂,Ki 为 1.4 nM。Mesembrine 还抑制磷酸二酯酶 4B (PDE4B),IC50为 7.8 μM。
T80014 Guvacine hydrobromide

GABA Receptor Membrane transporter/Ion channel; Neuroscience
Guvacine hydrobromide为槟榔中提取的生物碱,具有作为GABA摄取抑制剂的活性。该化合物对大鼠GAT-1、GAT-2和GAT-3的GABA摄取抑制作用具有不同的IC50值,分别为39 μM、58 μM及378 μM。
T37810 6',7'-Epoxybergamottin

Others Others
6'7'-Epoxybergamottin is a furanocoumarin found in grapefruit. It is a potent inhibitor of the cytochrome P450 (CYP) isoform CYP3A4 with an IC50 value of 0.30 ppm in a cell-free assay, 0.33 μM in HL7 human liver cells, and 0.22 μM in S9 human intestine cells. It has been studied in the context of drug interactions with grapefruit constituents. It is found in grapefruit juice at concentrations of 0.1-7.4 μM and inhibits the transport of talinolol , a permeability glycoprotein (P-gp/ABCB1) transpo...
T19290 DL-Lysine

(±)-2,6-Diaminocaproic acid

Others Others
DL-Lysine (Lysine) is an α-amino acid that is used in the biosynthesis of proteins.
T75436 Jatrorrhizine hydroxide

Others Others
Jatrorrhizine hydroxide, 一种从黄连中提取的生物碱,展现了神经保护、抗菌、抗疟原虫及抗氧化的活性。作为一种高效的乙酰胆碱酯酶(AChE)抑制剂(IC50=872 nM),其对BuChE的选择性高达115倍。此外,Jatrorrhizine hydroxide还能通过抑制uptake-2 transporter活性来减少血清素(5-HT)和去甲肾上腺素(NE)的摄取,表现出口服活性。

天然产物

5,7-Dimethoxyluteolin
Cat.No: TN6552
Synonym:
Target: Dopamine Receptor
Reserpine
Cat.No: T0791
Synonym: 利血平,Serpalan,Serpasil,Serpivite
Target: Others, Potassium Channel, MRP, Monoamine Transporter, Autophagy
Syrosingopine
Cat.No: TN2252
Synonym:
Target: Dopamine Receptor
Tormentic acid
Cat.No: TN1118
Synonym: 2Α,19Α-二羟基熊果酸,委陵菜酸
Target: Immunology/Inflammation related
Licarin B
Cat.No: T4S1545
Synonym: (-)-Licarin B,Licarine B,(-)-利卡灵B
Target: transporter, Antibacterial, PPAR
Azaphen
Cat.No: T7521
Synonym: Pipofezin hydrochloride,阿扎吩,Pipofezine hydrochloride,Azafen
Target: 5-HT Receptor, Serotonin Transporter
Cinchonidine
Cat.No: T1317
Synonym: 奎宁树,α-Quinidine,辛可尼丁,L-Cinchonidine
Target: 5-HT Receptor, Serotonin Transporter, Parasite
L-Arginine
Cat.No: T3S0364
Synonym: L-精氨酸,L-Arg,(S)-(+)-Arginine
Target: IL Receptor, Endogenous Metabolite, NO Synthase
D-Carnitine hydrochloride
Cat.No: T2203
Synonym: (S)-Carnitine Hydrochloride,L-Carnitine hydrochloride
Target: Others, Endogenous Metabolite
Escitalopram
Cat.No: T0185
Synonym: Seroplex,依他普仑,S-(+)-Citalopram,艾司西酞普兰,(S)-Citalopram
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Adrenergic Receptor, AChR, Norepinephrine, Histamine Receptor
Phloretin
Cat.No: T2924
Synonym: 根皮素,Dihydronaringenin,NSC 407292,RJC 02792
Target: SGLT, transporter, Endogenous Metabolite
Avicularin
Cat.No: T6S0117
Synonym: Fenicularin,扁蓄苷
Target: ERK
Sennidin A
Cat.No: TN1033
Synonym:
Target: HCV Protease, transporter, Akt, PI3K
Sennidin B
Cat.No: TN1034
Synonym:
Target: HCV Protease, transporter, Akt, PI3K
Rhoifolin
Cat.No: T2755
Synonym: 野漆树苷,Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside
Target: Others, p38 MAPK, NF-κB, transporter, IGF-1R, Autophagy
Indican
Cat.No: T19866
Synonym: NSC-87517,3-Indoxyl-beta-D-glucopyranoside,3-吲哚基-beta-D-吡喃葡萄糖苷,NSC 87517,NSC87517,Indoxyl-β-D-glucoside
Target: OAT, MRP
(3-Carboxypropyl)trimethylammonium chloride
Cat.No: T4702
Synonym: γ-Butyrobetaine hydrochloride,(3-羧丙基)三甲基氯化铵,(3-Carboxypropyl)trimethylammonium chlor
Target: Endogenous Metabolite
Taxol C
Cat.No: TN5118
Synonym:
Target: P-gp
Jatrorrhizine chloride
Cat.No: T4912
Synonym: 盐酸药根碱,Yatrorhizine chloride,Neprotine chloride
Target: Others, 5-HT Receptor, OCT, Antibacterial, AChE
Sarcosine
Cat.No: T6975
Synonym: Sarcosinic acid,Methylaminoacetic acid,Sarcosin,肌氨酸,Methylglycine,N-Methylaminoacetic acid,N-methylglycine
Target: Others, GlyT, Endogenous Metabolite
Trimethoprim
Cat.No: T1153
Synonym: NIH 204,BW 56-72,甲氧苄啶,NSC-106568
Target: DHFR, DNA/RNA Synthesis, Antifolate, Antibacterial, Antibiotic
DL-Norepinephrine hydrochloride
Cat.No: T13655
Synonym: 去甲肾上腺素盐酸盐,Lys,DL-lysine
Target: Adrenergic Receptor
D-tetrahydropalmatine
Cat.No: T4S0779
Synonym:
Target: Others, Dopamine Receptor
Jatrorrhizine
Cat.No: T3933
Synonym: Yatrorizine,neprotin,药根碱
Target: MAO, 5-HT Receptor, Antibacterial, AChE
Mesembrenone
Cat.No: T19772
Synonym: (+)-Mesembrenone
Target: Others
Falcarindiol
Cat.No: T72961
Synonym: 法卡林二醇
Target: Others
Arecaidine hydrobromide
Cat.No: T80013
Synonym:
Target: GABA Receptor
4,6-O-Ethylidene-α-D-glucose
Cat.No: T72172
Synonym: Ethylidene-glucose
Target: Others
Norbatzelladine L
Cat.No: T72645
Synonym:
Target: Others
Mesembrine
Cat.No: T73857
Synonym:
Target: Others
Guvacine hydrobromide
Cat.No: T80014
Synonym:
Target: GABA Receptor
6',7'-Epoxybergamottin
Cat.No: T37810
Synonym:
Target: Others
DL-Lysine
Cat.No: T19290
Synonym: (±)-2,6-Diaminocaproic acid
Target: Others
Jatrorrhizine hydroxide
Cat.No: T75436
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPY-02829 FCGRT & B2M Heterodimer Protein, Rat, Recombinant (His)

Fc fragment of IgG, receptor, transporter, alpha,Fc...

Rat HEK293 Cells
FCGRT & B2M Heterodimer Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44 kDa and the accession number is P13599&P07151.
TMPY-02830 FCGRT & B2M Heterodimer Protein, Cynomolgus, Recombinant (His)

Fc fragment of IgG, receptor, transporter, alpha,Fc...

Cynomolgus HEK293 Cells
FCGRT & B2M Heterodimer Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.5 kDa and the accession number is Q8SPV9&Q8SPW0.
TMPY-05650 FCGRT & B2M Heterodimer Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated

Fc fragment of IgG, receptor, transporter, alpha,Fc...

Cynomolgus HEK293 Cells
FCGRT & B2M Heterodimer Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 45.3 kDa and the accession number is Q8SPV9&Q8SPW0.
TMPY-02811 FCGRT & B2M Heterodimer Protein, Mouse, Recombinant (His)

Fc fragment of IgG, receptor, transporter, alpha,Fc...

Mouse HEK293 Cells
FCGRT & B2M Heterodimer Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.5 kDa and the accession number is Q61559&P01887.
TMPY-05539 FCGRT & B2M Heterodimer Protein, Human, Recombinant (His), Biotinylated

Fc fragment of IgG, receptor, transporter, α,FCRN,α...

Human HEK293 Cells
FCGRT & B2M Heterodimer Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.5 kDa and the accession number is P55899&P61769.
TMPY-02082 FCGRT & B2M Heterodimer Protein, Human, Recombinant (His)

Fc fragment of IgG, receptor, transporter, alpha,al...

Human HEK293 Cells
FCGRT & B2M Heterodimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.5 kDa and the accession number is P55899-1&P61769.
TMPY-01938 CD98 Protein, Human, Recombinant (His)

4T2HC,4F2,CD98HC,NACAE,MDU1,4F2HC,CD98,solute carrier family...

Human HEK293 Cells
CD98 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P08195-1.
TMPH-02123 SLC2A9 Protein, Human, Recombinant (His)

Urate transporter,SLC2A9,Glucose transporter

Human E. coli
Urate transporter, which may play a role in the urate reabsorption by proximal tubules. Does not transport glucose, fructose or galactose.
TMPY-05148 FCGRT & B2M Heterodimer Protein, Rat, Recombinant (His), Biotinylated

Fc fragment of IgG, receptor, transporter, α,Fc fra...

Rat HEK293 Cells
FCGRT & B2M Heterodimer Protein, Rat, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44 kDa and the accession number is P13599&P07151.
TMPY-02358 CD98 Protein, Mouse, Recombinant (His)

NACAE,AI314110,Ly-m10,Cd98,Mgp-2hc,4F2HC,Ly10,4F2,solute car...

Mouse HEK293 Cells
CD98 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P10852-2.
TMPY-02209 CUTC Protein, Human, Recombinant (His)

CGI-32,cutC copper transporter

Human E. coli
Copper homeostasis protein cutC homolog, also known as CGI-32 and CUTC, is a cytoplasm and nucleus protein which belongs to theCutC family. CUTC may play a role in copper homeostasis. It can bind one Cu1+per subunit. Copper is an essential trace element to life and particularly plays a pivotal role in the physiology of aerobic organisms. Copper is a micronutrient that is required for proper metabolic functioning of most prokaryotic and eukaryotic organisms. To sustain an adequate supply o...
TMPH-02122 SLC2A1 Protein, Human, Recombinant (His & Myc)

Glucose transporter type 1, erythrocyte/brain,HepG2...

Human E. coli
Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors. SLC2A1 ...
TMPY-05149 FCGRT & B2M Heterodimer Protein, Cynomolgus, Recombinant (His), Biotinylated

Fc fragment of IgG, receptor, transporter, α,Fc fra...

Cynomolgus HEK293 Cells
FCGRT & B2M Heterodimer Protein, Cynomolgus, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.5 kDa and the accession number is Q8SPV9&Q8SPW0.
TMPY-05649 FCGRT & B2M Heterodimer Protein, Mouse, Recombinant (His & Avi), Biotinylated

Fc fragment of IgG, receptor, transporter, alpha,Fc...

Mouse HEK293 Cells
FCGRT & B2M Heterodimer Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 46 kDa and the accession number is Q61559.
TMPH-01696 SLC16A4 Protein, Human, Recombinant (His)

SLC16A4,Monocarboxylate transporter 5,Solute carrie...

Human E. coli
Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. SLC16A4 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 17.7 kDa and the accession number is O15374.
TMPY-05147 FCGRT & B2M Heterodimer Protein, Mouse, Recombinant (His), Biotinylated

Fc fragment of IgG, receptor, transporter, alpha,Fc...

Mouse HEK293 Cells
FCGRT & B2M Heterodimer Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.2 kDa and the accession number is Q61559&P01887.
TMPY-03857 MMGT1 Protein, Human, Recombinant (His)

membrane magnesium transporter 1,TMEM32,EMC5

Human HEK293 Cells
MMGT1 (Membrane Magnesium Transporter 1, also known as EMC5 and TMEM32) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. The encoded protein belongs to the membrane magnesium transporter (TC 1.A.67) family which is a group of magnesium transporters that are part of the TOG superfamily. It mediates Mg(2+) transport. MMGT1 is described as having 335 amino acids and five TMSs with an N-terminal cleavage site and some phosphorylation sites. It is widely expressed ...
TMPH-03373 SLC2A1 Protein, Rat, Recombinant (His & Myc)

Glucose transporter type 1, erythrocyte/brain,Solut...

Rat E. coli
Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors. SLC2A1 ...
TMPH-02528 SLC7A10 Protein, Mouse, Recombinant (His & SUMOstar)

Slc7a10,Solute carrier family 7 member 10,Asc-type amino aci...

Mouse P. pastoris (Yeast)
Sodium-independent, high affinity transport of small neutral D- and L-amino acids and amino acid-related compounds. May play a role in the modulation of glutamatergic transmission through mobilization of D-serine at the glutamatergic synapse. SLC7A10 Protein, Mouse, Recombinant (His & SUMOstar) is expressed in yeast with N-His tag. The predicted molecular weight is 22.5 kDa and the accession number is P63115.
TMPH-03414 RT0041 Protein, Rickettsia typhi, Recombinant (His & Myc)

Probable ABC transporter permease protein RT0041

Rickettsia typhi E. coli
Could be part of an ABC transporter complex. RT0041 Protein, Rickettsia typhi, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 15.7 kDa and the accession number is Q68XW4.
TMPH-00714 SapA Protein, E. coli, Recombinant (His & Myc)

sapA,Probable ABC transporter periplasmic-binding p...

E. coli E. coli
Not part of a putrescine export system. Very similar to a S.typhimurium protein implicated in antimicrobial peptide resistance, but the SapBCDF operon in E.coli is implicated in putrescine export. SapA Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 66.9 kDa and the accession number is Q47622.
TMPH-01314 SLC1A3 Protein, Human, Recombinant (His & KSI)

Excitatory amino acid transporter 1,Solute carrier ...

Human E. coli
SLC1A3 Protein, Human, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 25.5 kDa and the accession number is P43003.
TMPY-05036 FCGRT & B2M Heterodimer Protein, Human, Recombinant (His & Avi)

Fc fragment of IgG, receptor, transporter, alpha,α-...

Human HEK293 Cells
FCGRT & B2M Heterodimer Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 45.3 kDa and the accession number is NP_004098.1&NP_004039.1.
TMPY-05448 FCGRT & B2M Heterodimer Protein, Human, Recombinant (His & Avi), Biotinylated

Fc fragment of IgG, receptor, transporter, alpha,al...

Human HEK293 Cells
FCGRT & B2M Heterodimer Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 45.3 kDa and the accession number is NP_004098.1&NP_004039.1.
TMPH-02124 SLC23A2 Protein, Human, Recombinant (His)

Nucleobase transporter-like 1 protein,SLC23A2,Na(+)...

Human E. coli
Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate. SLC23A2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 71.3 kDa and the accession number is Q9UGH3.
TMPH-02016 SLC19A1 Protein, Human, Recombinant (His & Myc)

Reduced folate carrier protein,Intestinal folate carrier 1,C...

Human E. coli
SLC19A1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPH-02125 SLCO2B1 Protein, Human, Recombinant (His & Myc)

Solute carrier family 21 member 9,Solute carrier organic ani...

Human E. coli
Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost.
TMPH-01604 SLC7A5 Protein, Human, Recombinant (His & Myc & SUMO)

SLC7A5,y+ system cationic amino acid transporter,La...

Human E. coli
SLC7A5 Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 19.7 kDa and the accession number is Q01650.
TMPH-01711 ABCC1 Protein, Human, Recombinant (His)

MRP,ATP-binding cassette sub-family C member 1,Leukotriene C...

Human E. coli
ABCC1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.9 kDa and the accession number is P33527.
TMPY-04631 CD98 Protein, Rat, Recombinant (hFc)

solute carrier family 3 (amino acid transporter hea...

Rat HEK293 Cells
CD98 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 75.8 kDa and the accession number is Q794F9.
TMPY-03307 CD98 Protein, Rat, Recombinant (His)

solute carrier family 3 (amino acid transporter hea...

Rat HEK293 Cells
CD98 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.7 kDa and the accession number is Q794F9.
TMPH-03591 PsaA Protein, S. pneumoniae, Recombinant (His & Myc)

Manganese ABC transporter substrate-binding lipopro...

Streptococcus pneumoniae E. coli
Part of an ABC transporter complex involved in manganese import. PsaA Protein, S. pneumoniae, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.9 kDa and the accession number is P42363.
TMPY-01118 SLC27A4/FATP4 Protein, Human, Recombinant (His)

FATP4,IPS,solute carrier family 27 (fatty acid transport...

Human HEK293 Cells
SLC27A4/ATG4B complex might act as a new potential therapeutic target of lung tumor chemotherapy. The solute carrier 27A (SLC27A) gene family encodes fatty acid transport proteins (FATPs) and includes 6 members. Autism spectrum disorders (ASD) are now recognized as disorders caused by impaired early brain development, it is possible that functional abnormalities of SLC27A genes may contribute to the pathogenesis of ASD. The expression of SLC27A3 and SLC27A4 in human neural stem cells derived fro...
TMPH-03589 PsaA Protein, S. oralis, Recombinant (His & Myc)

Manganese ABC transporter substrate-binding lipopro...

Streptococcus oralis E. coli
Part of an ATP-driven transport system. PsaA Protein, S. oralis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 40.1 kDa and the accession number is Q9L5W9.
TMPH-03590 PsaA Protein, S. pneumoniae (strain ATCC BAA-255/R6), Recombinant (His & Myc)

psaA,Manganese ABC transporter substrate-binding li...

Streptococcus pneumoniae E. coli
Part of an ATP-driven transport system. PsaA Protein, S. pneumoniae (strain ATCC BAA-255/R6), Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 40.0 kDa and the accession number is P0A4G3.
TMPJ-00583 CDH17 Protein, Human, Recombinant (His)

Intestinal Peptide-Associated Transporter HPT-1,Liv...

Human HEK293 Cells
Cadherin-17 is a single-pass type I membrane protein that belongs to the cadherin superfamily. Cadherin-17 consists of one extracellular region containing seven cadherin domains and one transmembrane region but it lacks the conserved cytoplasmic domain. Cadherin-17 is expressed in the gastrointestinal tract and pancreatic duct. Cadherins are calcium dependent cell adhesion proteins and preferentially interact with each other in a homophilic manner in connecting cells. Cadherin-17 may have a role...
TMPH-02979 SLC30A8 Protein, Mouse, Recombinant (His)

Slc30a8,Proton-coupled zinc antiporter SLC30A8,Zinc tran...

Mouse E. coli
Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta-cells. SLC30A8 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 43.0 kDa and the accession number is Q8BGG0.
TMPH-02322 SLC30A10 Protein, Human, Recombinant (His & Myc)

SLC30A10,Zinc transporter 10,Calcium/manganese anti...

Human E. coli
SLC30A10 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 27.9 kDa and the accession number is Q6XR72.
TMPH-02323 SLC30A8 Protein, Human, Recombinant (His)

Zinc transporter 8,Proton-coupled zinc antiporter S...

Human E. coli
Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta-cells. SLC30A8 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 43.6 kDa and the accession number is Q8IWU4.
TMPH-01468 SLC31A1 Protein, Human, Recombinant (His & SUMO)

Copper transporter 1,SLC31A1,High affinity copper u...

Human E. coli
SLC31A1 Protein, Human, Recombinant (His & SUMO) is expressed in in vitro E. coli expression system.
TMPH-02120 SLC5A5 Protein, Human, Recombinant (His)

Sodium-iodide symporter,SLC5A5,Natrium iodide transporte...

Human E. coli
Mediates iodide uptake in the thyroid gland. SLC5A5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 17.4 kDa and the accession number is Q92911.
TMPH-01516 FCGRT Protein, Human, Recombinant (His)

Neonatal Fc receptor,IgG receptor FcRn large subunit p51,FCG...

Human HEK293 Cells
Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids. Throughout life, contributes to effective humoral immunity by recycling IgG and exten...
TMPH-01517 FCGRT Protein, Human, Recombinant (GST)

IgG Fc fragment receptor transporter alpha chain,Ne...

Human E. coli
Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids. Throughout life, contributes to effective humoral immunity by recycling IgG and exten...
TMPY-06611 CD98 Protein, Human, Recombinant (His), Biotinylated

4F2,4F2HC,MDU1,4T2HC,solute carrier family 3 (amino acid

Human HEK293 Cells
CD98 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.19 kDa and the accession number is P08195-1.
TMPH-02333 SLC25A19 Protein, Human, Recombinant (His)

Mitochondrial thiamine pyrophosphate transporter,SL...

Human E. coli
Mitochondrial transporter mediating uptake of thiamine pyrophosphate (ThPP) into mitochondria. SLC25A19 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 37.0 kDa and the accession number is Q9HC21.
TMPH-03400 SLC17A6 Protein, Rat, Recombinant (His)

Slc17a6,Vesicular glutamate transporter 2,Solute ca...

Rat P. pastoris (Yeast)
Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. Involved in the regulation of retinal hyaloid vessel regression during postnatal development. May also play a role in the endocrine glutamatergic system of other tissues such as pineal gland and pancreas. SLC17A6 Protein, Rat, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 11.1 kDa an...
TMPH-02324 SLC39A6 Protein, Human, Recombinant (His)

Solute carrier family 39 member 6,Zinc transporter ...

Human Baculovirus Insect Cells
May act as a zinc-influx transporter. SLC39A6 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 35.0 kDa and the accession number is Q13433.
TMPH-03750 SLC7A11 Protein, Human, Recombinant (His)

SLC7A11,Calcium channel blocker resistance protein CCBR1,Sol...

Human E. coli
Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate.
TMPH-00981 ABCB1 Protein, Human, Recombinant (His)

Multidrug resistance protein 1,P-glycoprotein 1,ATP-binding ...

Human E. coli
ABCB1 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-00206 Pertactin autotransporter Protein, Bordetella pertussis, Recombinant (His & SUMO)

prn,P.93,Pertactin autotransporter

Bordetella pertussis E. coli
Agglutinogen that binds to eukaryotic cells; a process mediated by the R-G-D sequence. Pertactin may have a role in bacterial adhesion, and thus play a role in virulence. May contribute to the disease state of whooping cough. Pertactin autotransporter Protein, Bordetella pertussis, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 45.8 kDa and the accession number is P14283.
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重组蛋白

FCGRT & B2M Heterodimer Protein, Rat, Recombinant (His)
Cat.No: TMPY-02829
Species: Rat
Expression System: HEK293 Cells
FCGRT & B2M Heterodimer Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-02830
Species: Cynomolgus
Expression System: HEK293 Cells
FCGRT & B2M Heterodimer Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05650
Species: Cynomolgus
Expression System: HEK293 Cells
FCGRT & B2M Heterodimer Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02811
Species: Mouse
Expression System: HEK293 Cells
FCGRT & B2M Heterodimer Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05539
Species: Human
Expression System: HEK293 Cells
FCGRT & B2M Heterodimer Protein, Human, Recombinant (His)
Cat.No: TMPY-02082
Species: Human
Expression System: HEK293 Cells
CD98 Protein, Human, Recombinant (His)
Cat.No: TMPY-01938
Species: Human
Expression System: HEK293 Cells
SLC2A9 Protein, Human, Recombinant (His)
Cat.No: TMPH-02123
Species: Human
Expression System: E. coli
FCGRT & B2M Heterodimer Protein, Rat, Recombinant (His), Biotinylated
Cat.No: TMPY-05148
Species: Rat
Expression System: HEK293 Cells
CD98 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02358
Species: Mouse
Expression System: HEK293 Cells
CUTC Protein, Human, Recombinant (His)
Cat.No: TMPY-02209
Species: Human
Expression System: E. coli
SLC2A1 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-02122
Species: Human
Expression System: E. coli
FCGRT & B2M Heterodimer Protein, Cynomolgus, Recombinant (His), Biotinylated
Cat.No: TMPY-05149
Species: Cynomolgus
Expression System: HEK293 Cells
FCGRT & B2M Heterodimer Protein, Mouse, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05649
Species: Mouse
Expression System: HEK293 Cells
SLC16A4 Protein, Human, Recombinant (His)
Cat.No: TMPH-01696
Species: Human
Expression System: E. coli
FCGRT & B2M Heterodimer Protein, Mouse, Recombinant (His), Biotinylated
Cat.No: TMPY-05147
Species: Mouse
Expression System: HEK293 Cells
MMGT1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03857
Species: Human
Expression System: HEK293 Cells
SLC2A1 Protein, Rat, Recombinant (His & Myc)
Cat.No: TMPH-03373
Species: Rat
Expression System: E. coli
SLC7A10 Protein, Mouse, Recombinant (His & SUMOstar)
Cat.No: TMPH-02528
Species: Mouse
Expression System: P. pastoris (Yeast)
RT0041 Protein, Rickettsia typhi, Recombinant (His & Myc)
Cat.No: TMPH-03414
Species: Rickettsia typhi
Expression System: E. coli
SapA Protein, E. coli, Recombinant (His & Myc)
Cat.No: TMPH-00714
Species: E. coli
Expression System: E. coli
SLC1A3 Protein, Human, Recombinant (His & KSI)
Cat.No: TMPH-01314
Species: Human
Expression System: E. coli
FCGRT & B2M Heterodimer Protein, Human, Recombinant (His & Avi)
Cat.No: TMPY-05036
Species: Human
Expression System: HEK293 Cells
FCGRT & B2M Heterodimer Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05448
Species: Human
Expression System: HEK293 Cells
SLC23A2 Protein, Human, Recombinant (His)
Cat.No: TMPH-02124
Species: Human
Expression System: E. coli
SLC19A1 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-02016
Species: Human
Expression System: E. coli
SLCO2B1 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-02125
Species: Human
Expression System: E. coli
SLC7A5 Protein, Human, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-01604
Species: Human
Expression System: E. coli
ABCC1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01711
Species: Human
Expression System: E. coli
CD98 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-04631
Species: Rat
Expression System: HEK293 Cells
CD98 Protein, Rat, Recombinant (His)
Cat.No: TMPY-03307
Species: Rat
Expression System: HEK293 Cells
PsaA Protein, S. pneumoniae, Recombinant (His & Myc)
Cat.No: TMPH-03591
Species: Streptococcus pneumoniae
Expression System: E. coli
SLC27A4/FATP4 Protein, Human, Recombinant (His)
Cat.No: TMPY-01118
Species: Human
Expression System: HEK293 Cells
PsaA Protein, S. oralis, Recombinant (His & Myc)
Cat.No: TMPH-03589
Species: Streptococcus oralis
Expression System: E. coli
PsaA Protein, S. pneumoniae (strain ATCC BAA-255/R6), Recombinant (His & Myc)
Cat.No: TMPH-03590
Species: Streptococcus pneumoniae
Expression System: E. coli
CDH17 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00583
Species: Human
Expression System: HEK293 Cells
SLC30A8 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02979
Species: Mouse
Expression System: E. coli
SLC30A10 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-02322
Species: Human
Expression System: E. coli
SLC30A8 Protein, Human, Recombinant (His)
Cat.No: TMPH-02323
Species: Human
Expression System: E. coli
SLC31A1 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01468
Species: Human
Expression System: E. coli
SLC5A5 Protein, Human, Recombinant (His)
Cat.No: TMPH-02120
Species: Human
Expression System: E. coli
FCGRT Protein, Human, Recombinant (His)
Cat.No: TMPH-01516
Species: Human
Expression System: HEK293 Cells
FCGRT Protein, Human, Recombinant (GST)
Cat.No: TMPH-01517
Species: Human
Expression System: E. coli
CD98 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-06611
Species: Human
Expression System: HEK293 Cells
SLC25A19 Protein, Human, Recombinant (His)
Cat.No: TMPH-02333
Species: Human
Expression System: E. coli
SLC17A6 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03400
Species: Rat
Expression System: P. pastoris (Yeast)
SLC39A6 Protein, Human, Recombinant (His)
Cat.No: TMPH-02324
Species: Human
Expression System: Baculovirus Insect Cells
SLC7A11 Protein, Human, Recombinant (His)
Cat.No: TMPH-03750
Species: Human
Expression System: E. coli
ABCB1 Protein, Human, Recombinant (His)
Cat.No: TMPH-00981
Species: Human
Expression System: E. coli
Pertactin autotransporter Protein, Bordetella pertussis, Recombinant (His & SUMO)
Cat.No: TMPH-00206
Species: Bordetella pertussis
Expression System: E. coli
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Cat. No. Product Name Target Signaling Pathways
T10842 Clomipramine D3

氯米帕明 D3

Others Others
Clomipramine D3 is the deuterium-labeled Clomipramine. Clomipramine is a serotonin transporter, norepinephrine transporter dopamine transporter blocker (Ki: 0.14, 54 and 3 nM).
T10842L Clomipramine D3 hydrochloride

Others Others
Clomipramine D3 hydrochloride is the deuterium-labeled Clomipramine. Clomipramine is a serotonin transporter, norepinephrine transporter dopamine transporter blocker (Ki: 0.14, 54 and 3 nM).
T70615 TAS-303

TAS-303 is a selective norepinephrine reuptake inhibitor which displays significant norepinephrine transporter (NET) inhibitory activity toward serotonin or dopamine transporters. Radioligand-binding studies showed that TAS-303 selectively and potently inhibited [3H]norepinephrine binding to the human NET.
TMIJ-0133 Empagliflozin-d4

Empagliflozin-d4 是 Empagliflozin 的氘代化合物。Empagliflozin 的 CAS 号为 864070-44-0。Empagliflozin 是有效的、选择性的钠葡萄糖协同转运蛋白-2 (SGLT-2) 抑制剂,对人 SGLT-2 的IC50为 3.1 nM。
TMIJ-0100 (3R,11bR)-Tetrabenazine-d6

(3R,11bR)-Tetrabenazine-d6 是 (3R,11bR)-Tetrabenazine 的氘代化合物。(3R,11bR)-Tetrabenazine 的 CAS 号为 1026016-83-0。(+)-Tetrabenazine是一种可逆的囊泡单胺转运蛋白2 (VMAT-2)抑制剂,对VMAT2转运的抑制作用是VMAT1的10倍。
TMIH-0013 (S)-Empagliflozin-d4

(S)-Empagliflozin-d4 是 (S)-Empagliflozin 的氘代化合物。(S)-Empagliflozin 的 CAS 号为 864070-44-0。Empagliflozin 是有效的、选择性的钠葡萄糖协同转运蛋白-2 (SGLT-2) 抑制剂,对人 SGLT-2 的IC50为 3.1 nM。
TMIJ-0153 Dapagliflozin-13C6 (glucitol-13C6)

Dapagliflozin-13C6 (glucitol-13C6) 是 Dapagliflozin 的 13C 的标记化合物。Dapagliflozin 的 CAS 号为 461432-26-8。Dapagliflozin竞争性的葡萄糖协同转运蛋白2 (SGLT2) 抑制剂,可促进尿液中葡萄糖的排泄,在糖尿病 (DM) 研究中具有价值。Dapagliflozin 诱导HIF1表达并减轻肾脏 IR 损伤。
TMIH-0209 Elobixibat-d5

Elobixibat-d5 是 Elobixibat 的氘代化合物。Elobixibat 的 CAS 号为 439087-18-0。Elobixibat 是回肠胆汁酸转运蛋白的抑制剂(小鼠、人和犬 IBAT 的 IC50:0.13 nM、0.53 nM 和 5.8 nM)。 Elobixibat 可用于慢性特发性便秘的研究。
T71206 Tiagabine-d6 hydrochloride

Tiagabine-d6 is intended for use as an internal standard for the quantification of tiagabine by GC- or LC-MS. Tiagabine is an inhibitor of GABA transporter 1. It inhibits seizures induced by DMCM in mice. Tiagabine reduces allodynia in a rodent model of neuropathic pain when used at a dose of 72.8 µmol/kg, and it acts synergistically with gabapentin to delay pain responses in mice in the hot plate test. Formulations containing tiagabine have been used as adjunctive therapies in the treatment of ...
TMIJ-0055 DL-Norepinephrine-d6 HCl

DL-Norepinephrine-d6 HCl 是 DL-NorepinephrineHCl 的氘代化合物。DL-NorepinephrineHCl 的 CAS 号为 55-27-6。DL-Norepinephrine hydrochloride 是一种靶向α1 adrenoceptor和β1 adrenoceptor的神经递质,可降低心内膜下氧分压。它是一种模拟内源性去甲肾上腺素的拟交感神经作用的合成苯乙胺。
T70960 Maprotiline-d3 hydrochloride

Maprotiline-d3 is intended for use as an internal standard for the quantification of maprotiline by GC- or LC-MS. Maprotiline is a tricyclic antidepressant. It binds to the norepinephrine transporter (NET) and is selective for NET over the serotonin and dopamine transporters. Maprotiline also binds to the serotonin (5-HT) receptor subtype 5-HT2A, as well as histamine H1, muscarinic acetylcholine, α1-adrenergic, and dopamine D2 receptors. In vivo, maprotiline inhibits norepinephrine reuptake in r...
T71981 Gliclazide-d4

Gliclazide-d4 is intended for use as an internal standard for the quantification of gliclazide by GC- or LC-MS. Gliclazide is a sulfonylurea and an inhibitor of pancreatic β-cell ATP-sensitive potassium (KATP) channels. It is selective for pancreatic β-cell over cardiac and arterial smooth muscle cell KATP channels. Gliclazide (5 μM) increases insulin-induced glucose uptake and glucose transporter 4 (GLUT4) translocation to the plasma membrane in a differentiated 3T3L1 adipocyte model of insulin...
T70313 Indoxyl Sulfate-d5 potassium salt

Indoxyl sulfate-d5 is intended for use as an internal standard for the quantification of indoxyl sulfate by GC- or LC-MS. Indoxyl sulfate is a uremic toxin and a metabolite of tryptophan. It is formed via sulfation of indole, an intermediate generated from tryptophan by intestinal bacteria, by the sulfotransferase (SULT) isoform 1A1 variant 2 (SULT1A1*2) in the liver. Indoxyl sulfate activates the aryl hydrocarbon receptor (AhR) in HepG2 40/6 hepatoma cells (EC50 = 12.1 nM in a reporter assay). ...

同位素标记化合物

Clomipramine D3
Cat.No: T10842
Synonym: 氯米帕明 D3
Target: Others
Clomipramine D3 hydrochloride
Cat.No: T10842L
Synonym:
Target: Others
TAS-303
Cat.No: T70615
Synonym:
Target:
Empagliflozin-d4
Cat.No: TMIJ-0133
Synonym:
Target:
(3R,11bR)-Tetrabenazine-d6
Cat.No: TMIJ-0100
Synonym:
Target:
(S)-Empagliflozin-d4
Cat.No: TMIH-0013
Synonym:
Target:
Dapagliflozin-13C6 (glucitol-13C6)
Cat.No: TMIJ-0153
Synonym:
Target:
Elobixibat-d5
Cat.No: TMIH-0209
Synonym:
Target:
Tiagabine-d6 hydrochloride
Cat.No: T71206
Synonym:
Target:
DL-Norepinephrine-d6 HCl
Cat.No: TMIJ-0055
Synonym:
Target:
Maprotiline-d3 hydrochloride
Cat.No: T70960
Synonym:
Target:
Gliclazide-d4
Cat.No: T71981
Synonym:
Target:
Indoxyl Sulfate-d5 potassium salt
Cat.No: T70313
Synonym:
Target:
TargetMol Loading
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