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Targets Recommended: Angiotensin-converting Enzyme (ACE) RAAS Others

357

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Cat. No. Product Name
L7110 抗高血压化合物库

678 compounds
678 种高血压相关的小分子,用于高通量和高内涵筛选;

化合物库

抗高血压化合物库
Cat.No: L7110
Compounds: 678
Cat. No. Product Name Target Signaling Pathways
TP1528 Angiotensin I/II (1-5)

Angiotensin I/II 1-5

RAAS; Others Endocrinology/Hormones; Others
Angiotensin I/II (1-5) 是由血管紧张素 I/II 肽转化而来,有 1-5 个氨基酸组成的多肽。血管紧张素 I 是由肾素对血管紧张素原的作用形成的,血管紧张素 I 可产生血管紧张素 II 。血管紧张素 II 用于高血压、特发性膜性肾病和肾素-血管紧张素系统的研究。
T7339 Angiotensin (1-7)

Ang-(1-7),Angiotensin 1-7,ASP-ARG-VAL-TYR-ILE-HIS-PRO

RAAS; Endogenous Metabolite Endocrinology/Hormones; Metabolism
Angiotensin (1-7) (ASP-ARG-VAL-TYR-ILE-HIS-PRO) 是肾素-血管紧张素系统中的内源性七肽。Angiotensin 1-7在心肌细胞中具有抗炎和抗纤维化活性,因此具有心脏保护作用。它能抑制血管紧张素转换酶和释放一氧化氮,是激肽诱导的血管舒张的局部协同调节剂。它阻断 Ang II 诱导的平滑肌细胞增殖和肥大,并显示对内皮的抗血管生成和生长抑制作用。它显示出抗炎活性。
TP1579 Angiotensin I/II (1-6)

Angiotensin I/II 1-6

RAAS; Others Endocrinology/Hormones; Others
Angiotensin I/II (1-6) 是由血管紧张素 I/II 肽转化而来,含有 1-6 个氨基酸的多肽。血管紧张素 I 被血管紧张素转换酶水解,形成具有生物活性的血管紧张素 II。血管紧张素 II 用于高血压、特发性膜性肾病和肾素-血管紧张素系统的研究。
TP1017L Angiotensin II 5-valine TFA

Angiotensin II 5-valine TFA(58-49-1 free base)

RAAS Endocrinology/Hormones
Angiotensin II 5-valine TFA 是血管紧张素受体的激动剂。
T7575L [Sar1, Ile8]-Angiotensin II 3TFA

[Sar1, Ile8]-Angiotensin II 3TFA(37827-06-8(free base))

Others Others
[Sar1, Ile8]-Angiotensin II 3TFA ([Sar1, Ile8]-Angiotensin II 3TFA (37827-06-8(free base))) 是一种对血管平滑肌具有多种作用的肽。
TP2446L Angiotensin amide acetate

血管紧张素胺,Angiotensin amide acetate(53-73-6 Free base)

Others Others
Angiotensin amide acetate 是Angiotensin amide 的衍生物。Angiotensin amide 是一种八肽酰胺,可以通过血管收缩来提高血压。
T7577 Angiotensin III, human, mouse

血管紧张素III,Angiotensin III, human, mouse(3TFA)

RAAS Endocrinology/Hormones
Angiotensin III, human, mouse (Angiotensin III, human, mouse(3TFA)) 是一种七肽,是血管紧张素 2 型受体 (AT2R) 激动剂,能够作用于 AT2R (IC50:0.648 nM)及 AT1R (IC50:21.1nM)。
T8560 Angiotensin II human acetate

Ang II acetate,DRVYIHPF acetate,Angiotensin II acetate,血管紧张素II

Apoptosis; RAAS Apoptosis; Endocrinology/Hormones
Angiotensin II human acetate (DRVYIHPF acetate) 是血管收缩剂,是肾素/血管紧张素系统的主要生物活性肽,在调节人类血压中起着核心作用。它刺激交感神经刺激,增加醛固酮生物合成和肾脏活动。它诱导血管平滑肌细胞生长,也诱导细胞凋亡。它通过 LOX-1 依赖的氧化还原敏感途径诱导内皮细胞毛细血管形成。
T21708L Angiotensin 1/2 + A (2 - 8) Acetate

Angiotensin 1/2 + A (2 - 8) Acetate (51833-76-2 Free base)

Others Others
Angiotensin 1/2 + A (2 - 8) Acetate 是一种血管收缩剂。
TP1295 Angiotensin I (human, mouse, rat)

Angiotensin 1 Human,血管紧张素 1 (人)

Others Others
Angiotensin I (human, mouse, rat) 是血管紧张素Ⅱ的前体物质,在血管紧张素转化酶 (ACE) 的参与下裂解成血管紧张素Ⅱ。
T7663L Angiotensin 1/2 (1-9) TFA

Angiotensin 1/2 (1-9) TFA (34273-12-6 free base)

Others Others
Angiotensin 1/2 (1-9) TFA(34273-12-6(free base)) 含有从血管紧张素 I/II 肽转化而来的氨基酸 1-9。
T35834L (Sar¹)-Angiotensin II acetate

RAAS Endocrinology/Hormones
(Sar¹)-Angiotensin II acetate 是血管紧张素 II 的类似物,是血管紧张素 AT1 受体的特异性激动剂。它与富含脑膜的颗粒结合,Kd 为 2.7 nM。它可以刺激胚胎鸡肌细胞中的蛋白质合成和细胞生长。
T7575L1 [Sar1, Ile8]-Angiotensin II acetate

RAAS Endocrinology/Hormones
[Sar1, Ile8]-Angiotensin II acetate 可激活 NADPH 和 NADH 氧化酶,并刺激血管平滑肌细胞中超氧阴离子的形成。 [Sar1, Ile8]-Angiotensin II acetate 对血管平滑肌有多种作用,包括正常动脉的收缩和培养细胞或病变血管的肥大或增生。
T7743 ANGIOTENSIN IV TFA(12676-15-2(free base))

RAAS Endocrinology/Hormones
ANGIOTENSIN IV TFA(12676-15-2(free base)) 是一种不太有效的血管紧张素 AT1 受体激动剂。
T22574L Angiotensin 1/2 (5-7) acetate

RAAS Endocrinology/Hormones
Angiotensin 1/2 (5-7) acetate 是一种具有 H2N-Ile-His-Pro-OH 序列的肽。血管紧张素是一种寡肽,是一种激素和一种强大的双肽原。它来源于前体分子血管紧张素原,一种在肝脏中产生的血清球蛋白。它在肾素-血管紧张素系统中起重要作用。
T35834 (Sar1)-Angiotensin II

(Sar¹)-Angiotensin II

The substitution with Sar at position 1 of angiotensin II resulted in a partial agonistic activity.
T5824 Angiotensin II (3-8), human

Angiotensin IV

RAAS Endocrinology/Hormones
Angiotensin II (3-8), human 是活性稍弱的血管紧张素AT1受体激动剂。
TP2370 Angiotensin pentapeptide

Angiotensin II (4-8),(Des-1,2,3)angiotensin II

Angiotensin pentapeptide is a peptide.
TP2446 Angiotensin amide

Angiotensinamide,Hypertensine,Angiotensin,NSC 107678,NSC-107678

Angiotensin amide, an octapeptide amide, can be used to increase blood pressure by vasoconstriction.
T7575 [Sar1, Ile8]-Angiotensin II

[Sar1, Ile8]-Angiotensin II(3TFA)

RAAS; Others Endocrinology/Hormones; Others
[Sar1, Ile8]-Angiotensin II 是一种在血管平滑肌细胞中有多种作用(如正常动脉的收缩,培养的细胞或病变血管的肥大或增生等)的多肽,。
TP1224 [Sar1, Ile8]-Angiotensin II TFA

Angiotensin 2 TFA,AngiotensinII TFA

[Sar1, Ile8]-Angiotensin II (TFA) is a peptide compound that exerts various effects on vascular smooth muscle. These effects include the contraction of normal arteries as well as the hypertrophy or hyperplasia of cultured cells or diseased vessels.
TP1017 Angiotensin II 5-valine

Valine angiotensin II,5-L-Valine angiotensin II,血管紧张素 Ⅱ 5-缬氨酸

ngiotensin II 5-valine is an angiotensin II analog which is an agonist at angiotensin receptors.
T10322 Angiotensin III

Others Others
Angiotensin III is an agonist of angiotensin 1 (AT1) and AT2 receptor.
T31096 Crinia-angiotensin

Others Others
Crinia-angiotensin is an Angiotensin II-like undecapeptide from the skin of Australian frog Crinia georgiana.
T10322L Angiotensin III TFA (12687-51-3 free base)

Angiotensin III TFA

Others Others
Angiotensin III TFA is an agonist of angiotensin 1 (AT1) and AT2 receptor.
T37495 Angiotensin (1-7) (acetate)

Angiotensin 1-7 (Ang-(1-7)) acetate 是RAS中的一种内源性七肽,具备心脏保护作用,主要表现为对心肌细胞的抗炎与抗纤维化活性。该化合物能抑制纯化的犬ACE活性(IC50=0.65 μM),通过降低ACE活性并促进一氧化氮释放,作为血管舒张调节的局部协同因子。此外,Angiotensin 1-7 acetate 可阻止血管紧张素Ⅱ诱发的平滑肌细胞增殖和肥大,同时对内皮细胞表现出抗血管生成和生长抑制作用。
T38697 [Tyr(P)4] Angiotensin II

[Tyr(P)4] Angiotensin II is a peptide that exerts a multitude of effects on vascular smooth muscle. These effects include the contraction of normal arteries, as well as the induction of hypertrophy or hyperplasia in cultured cells or diseased vessels.
T36622 Angiotensin I/II (1-6) (TFA)

Angiotensin I/II (1-6) TFA is a chemical compound comprising amino acids 1-6. It is derived from the Angiotensin I/II peptide, which is formed by the cleavage of the precursor angiotensinogen by renin. The resulting Angiotensin I is then hydrolyzed by angiotensin-converting enzyme (ACE) to produce biologically active Angiotensin II. Angiotensin II has been extensively studied for its potential applications in the treatment of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Neph...
TP2464 Pentasarcosyl angiotensin II

(Sar)5 aii

Pentasarcosyl angiotensin II is a synthetic analog of angiotensin II.
T22575 Angiotensin Fragment 1-7 (acetate)

Others Others
Angiotensin Fragment 1-7 is a type 1 angiotensin II receptor agonist. In the renin-angiotensin system, angiotensin I is cleaved by the angiotensin-converting enzyme to form angiotensin II, which has effects on fluid and electrolyte, as well as homeostasis
TP1522 Angiotensin II (5-8), human

Angiotensin II (5-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II
T22574 Angiotensin 1/2 (5-7)

Others Others
Angiotensin 1/2 (5-7) is a peptide with the sequence H2N-Ile-His-Pro-OH. Angiotensin is an oligopeptide and is a hormone and a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It plays a
T7663 Angiotensin 1/2 (1-9)

Others Others
Angiotensin 1/2 (1-9) 含有从血管紧张素 I/II 肽转化而来的氨基酸 1-9。
TP1609 Angiotensin II (1-4), human

Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure. Angiotensin also potentiates the release of norepinephrine by a direct action on postganglionic sympathetic fibers.
T22572 Angiotensin 1/2 (1-7) amide

Others Others
Angiotensin I/II (1-7) amide is a peptide analog to angiotensin II that is used as a vasopressor in the treatment of certain types of shock and circulatory collapse. Angiotensin I/II amide is an amide derivative of angiotensin II that is a powerful vasoco
T22573 Angiotensin 1/2 (2-7)

Others Others
Angiotensin I/II (2-7) is a peptide that contains the amino acids 2-7 and is converted from Angiotensin I/II peptide. Angiotensin is a peptide hormone that causes vasoconstriction and a subsequent increase in blood pressure. Angiotensin also stimulates th
TP2220 Angiotensin 1/2 (1-8) amide

Others Others
Angiotensin 1/2 (1-8) amide (H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-amide) is a peptide analog to angiotensin II that is used as a vasopressor agent in the treatment of certain types of shock and circulatory collapse. It is a potent vasoconstrictor and is us
T10323 Angiotensin II (3-8), human TFA

RAAS Endocrinology/Hormones
Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.
TP1661 Angiotensin II (1-4), human TFA

Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure.
TP2447 Angiotensin I, asn(1)-val(5)-gly(9)-

Angiotensin I, asn(1)-val(5)-gly(9)- is isolated from the plasma of American eel, Anquilla rostrata.
T76169 Angiotensin-converting enzyme

Angiotensin-converting enzyme (ACE)血管紧张素转换酶是一种二羧基肽酶,它将非活性的血管紧张素 I (Ang I) 转化为活性的 Ang II,并降解活性的缓激肽 (BK)。Angiotensin-converting enzyme 是一种有效的血管收缩剂,常用于生化研究。
TP1929L1 Saralasin acetate(34273-10-4 free base)

RAAS Endocrinology/Hormones
Saralasin acetate(34273-10-4 free base) 是一种非选择性血管紧张素 II 拮抗剂。
T83483 [Val4] Angiotensin III

[Val4] Angiotensin III为血管紧张素III类肽,作为Gαq和βarr2反应的高效全激动剂,其pEC50值分别为8.31和8.44。
T74142 Angiotensin II human TFA

Angiotensin II human (Angiotensin II) TFA 作为肾素/血管紧张素系统中关键的生物活性肽,扮演着血管收缩剂的角色并在调节人体血压中发挥中心作用。其主要通过与 G 蛋白偶联受体 (GPCRs)、血管紧张素 II 1型受体 (AT1R) 和血管紧张素 II 2型受体 (AT2R) 的相互作用来介导效应,包括刺激交感神经系统、增加醛固酮的生物合成和肾脏功能。此外,Angiotensin II human TFA 促进血管平滑肌细胞的生长和 I 型及 III 型胶原在成纤维细胞中的合成,导致血管壁与心肌增厚及纤维化,并诱导细胞凋亡。还通过LOX-1依赖的氧化还原敏感路径诱导内皮细胞中的毛细血管形成。
T76634 (Sar1,Ile4,8)-Angiotensin II

(Sar1,Ile4,8)-Angiotensin II是一种对angiotensin II type 1 receptor (AT1R)具有功能选择性的激动剂,能增强胰岛素受体 (IR) 信号和糖原合成,同时还能促进Akt和GSK3α/β的磷酸化,这一过程被胰岛素刺激所增强。
T75975 Angiotensin III, human, mouse TFA

Angiotensin III, human, mouse (TFA) 是一种血管紧张素。
T7510 Leucylarginylproline

RAAS Endocrinology/Hormones
Leucylarginylproline 是一种血管紧张素转换酶抑制剂,IC50=为0.27μM。
T1484 Perindoprilat

Perindoprilate,培哚普利

RAAS; MRP; AChR Endocrinology/Hormones; Immunology/Inflammation; Neuroscience
Perindoprilat (Perindoprilate) 是一种血管紧张素转换酶抑制剂。
T2531 Eprosartan Mesylate

SKF-108566J,甲磺酸依普罗沙坦

RAAS Endocrinology/Hormones
Eprosartan Mesylate (SKF-108566J) 是一种具有选择性、竞争性血管紧张素 II 受体拮抗剂,是具有口服活性的非肽。它结合血管紧张素 II 受体,在大鼠和人类肾上腺皮质膜中的IC50值分别为 9.2 nM 和 3.9 nM,可用作降压剂。
T7714 Temocapil

Tyrosinase Proteases/Proteasome
Temocapil 是一种酪氨酸激酶抑制剂。

化合物

Angiotensin I/II (1-5)
Cat.No: TP1528
Synonym: Angiotensin I/II 1-5
Target: RAAS, Others
Angiotensin (1-7)
Cat.No: T7339
Synonym: Ang-(1-7),Angiotensin 1-7,ASP-ARG-VAL-TYR-ILE-HIS-PRO
Target: RAAS, Endogenous Metabolite
Angiotensin I/II (1-6)
Cat.No: TP1579
Synonym: Angiotensin I/II 1-6
Target: RAAS, Others
Angiotensin II 5-valine TFA
Cat.No: TP1017L
Synonym: Angiotensin II 5-valine TFA(58-49-1 free base)
Target: RAAS
[Sar1, Ile8]-Angiotensin II 3TFA
Cat.No: T7575L
Synonym: [Sar1, Ile8]-Angiotensin II 3TFA(37827-06-8(free base))
Target: Others
Angiotensin amide acetate
Cat.No: TP2446L
Synonym: 血管紧张素胺,Angiotensin amide acetate(53-73-6 Free base)
Target: Others
Angiotensin III, human, mouse
Cat.No: T7577
Synonym: 血管紧张素III,Angiotensin III, human, mouse(3TFA)
Target: RAAS
Angiotensin II human acetate
Cat.No: T8560
Synonym: Ang II acetate,DRVYIHPF acetate,Angiotensin II acetate,血管紧张素II
Target: Apoptosis, RAAS
Angiotensin 1/2 + A (2 - 8) Acetate
Cat.No: T21708L
Synonym: Angiotensin 1/2 + A (2 - 8) Acetate (51833-76-2 Free base)
Target: Others
Angiotensin I (human, mouse, rat)
Cat.No: TP1295
Synonym: Angiotensin 1 Human,血管紧张素 1 (人)
Target: Others
Angiotensin 1/2 (1-9) TFA
Cat.No: T7663L
Synonym: Angiotensin 1/2 (1-9) TFA (34273-12-6 free base)
Target: Others
(Sar¹)-Angiotensin II acetate
Cat.No: T35834L
Synonym:
Target: RAAS
[Sar1, Ile8]-Angiotensin II acetate
Cat.No: T7575L1
Synonym:
Target: RAAS
ANGIOTENSIN IV TFA(12676-15-2(free base))
Cat.No: T7743
Synonym:
Target: RAAS
Angiotensin 1/2 (5-7) acetate
Cat.No: T22574L
Synonym:
Target: RAAS
(Sar1)-Angiotensin II
Cat.No: T35834
Synonym: (Sar¹)-Angiotensin II
Target:
Angiotensin II (3-8), human
Cat.No: T5824
Synonym: Angiotensin IV
Target: RAAS
Angiotensin pentapeptide
Cat.No: TP2370
Synonym: Angiotensin II (4-8),(Des-1,2,3)angiotensin II
Target:
Angiotensin amide
Cat.No: TP2446
Synonym: Angiotensinamide,Hypertensine,Angiotensin,NSC 107678,NSC-107678
Target:
[Sar1, Ile8]-Angiotensin II
Cat.No: T7575
Synonym: [Sar1, Ile8]-Angiotensin II(3TFA)
Target: RAAS, Others
[Sar1, Ile8]-Angiotensin II TFA
Cat.No: TP1224
Synonym: Angiotensin 2 TFA,AngiotensinII TFA
Target:
Angiotensin II 5-valine
Cat.No: TP1017
Synonym: Valine angiotensin II,5-L-Valine angiotensin II,血管紧张素 Ⅱ 5-缬氨酸
Target:
Angiotensin III
Cat.No: T10322
Synonym:
Target: Others
Crinia-angiotensin
Cat.No: T31096
Synonym:
Target: Others
Angiotensin III TFA (12687-51-3 free base)
Cat.No: T10322L
Synonym: Angiotensin III TFA
Target: Others
Angiotensin (1-7) (acetate)
Cat.No: T37495
Synonym:
Target:
[Tyr(P)4] Angiotensin II
Cat.No: T38697
Synonym:
Target:
Angiotensin I/II (1-6) (TFA)
Cat.No: T36622
Synonym:
Target:
Pentasarcosyl angiotensin II
Cat.No: TP2464
Synonym: (Sar)5 aii
Target:
Angiotensin Fragment 1-7 (acetate)
Cat.No: T22575
Synonym:
Target: Others
Angiotensin II (5-8), human
Cat.No: TP1522
Synonym:
Target:
Angiotensin 1/2 (5-7)
Cat.No: T22574
Synonym:
Target: Others
Angiotensin 1/2 (1-9)
Cat.No: T7663
Synonym:
Target: Others
Angiotensin II (1-4), human
Cat.No: TP1609
Synonym:
Target:
Angiotensin 1/2 (1-7) amide
Cat.No: T22572
Synonym:
Target: Others
Angiotensin 1/2 (2-7)
Cat.No: T22573
Synonym:
Target: Others
Angiotensin 1/2 (1-8) amide
Cat.No: TP2220
Synonym:
Target: Others
Angiotensin II (3-8), human TFA
Cat.No: T10323
Synonym:
Target: RAAS
Angiotensin II (1-4), human TFA
Cat.No: TP1661
Synonym:
Target:
Angiotensin I, asn(1)-val(5)-gly(9)-
Cat.No: TP2447
Synonym:
Target:
Angiotensin-converting enzyme
Cat.No: T76169
Synonym:
Target:
Saralasin acetate(34273-10-4 free base)
Cat.No: TP1929L1
Synonym:
Target: RAAS
[Val4] Angiotensin III
Cat.No: T83483
Synonym:
Target:
Angiotensin II human TFA
Cat.No: T74142
Synonym:
Target:
(Sar1,Ile4,8)-Angiotensin II
Cat.No: T76634
Synonym:
Target:
Angiotensin III, human, mouse TFA
Cat.No: T75975
Synonym:
Target:
Leucylarginylproline
Cat.No: T7510
Synonym:
Target: RAAS
Perindoprilat
Cat.No: T1484
Synonym: Perindoprilate,培哚普利
Target: RAAS, MRP, AChR
Eprosartan Mesylate
Cat.No: T2531
Synonym: SKF-108566J,甲磺酸依普罗沙坦
Target: RAAS
Temocapil
Cat.No: T7714
Synonym:
Target: Tyrosinase
Cat. No. Product Name Target Signaling Pathways
T7040 Angiotensin II human

DRVYIHPF,Angiotensin II,Hypertensin II,血管紧张素Ⅱ,Ang II,血管紧张素II

Apoptosis; RAAS Apoptosis; Endocrinology/Hormones
Angiotensin II human (Ang II) 是一种生物活性肽,一种血管收缩剂。Angiotensin II 可以与 AT1R 和 AT2R 相互作用,调节人类血压,刺激交感神经,增加醛固酮生物合成和肾脏活动。
T5S0106 Peimisine

贝母辛,Ebeiensine

RAAS; AChR Endocrinology/Hormones; Neuroscience
Peimisine (Ebeiensine) 非竞争性拮抗气管平滑肌 M 受体,抑制 Ach 引起的平滑肌收缩。它兴奋 β 受体和拮抗内钙释放,促进一氧化氮释放,可舒张气管平滑肌,有平喘作用。
T13299 Vicenin 3

维采宁-3,维采宁 3

RAAS Endocrinology/Hormones
Vicenin 3来源于广金钱草的地上部分。Vicenin 3是血管紧张素转换酶抑制剂,IC50=46.91 μM。
T8270 Deserpidine

地舍平,Harmonyl

RAAS Endocrinology/Hormones
Deserpidine (Harmonyl) 是从 Rauwolfia canescens 的根中分离的生物碱。Deserpidine 与 Reserpine 相关。Deserpidine 是竞争性血管紧张素转化酶抑制剂,可以被用作抗高血压药以及镇定剂。Deserpidine 还减少了肾上腺皮质血管紧张素 II 诱导的醛固酮分泌。
T5796 Plantainoside D

Isoplantamajoside,车前草苷D

RAAS; PKC Chromatin/Epigenetic; Cytoskeletal Signaling; Endocrinology/Hormones
Plantainoside D (Isoplantamajoside) 可以抑制 ACE ,IC50=2.17 mM。Plantainoside D 也是IKK-β抑制剂。
T21418 Lisinopril

Linopril,赖诺普利,Zestril,Prinivil,Lisipril

RAAS Endocrinology/Hormones
Lisinopril (Prinivil) 是一种血管紧张素转化酶抑制剂,能够作用于高血压,充血性心力衰竭和心脏病等。
T3851 Vicenin 2

Vicenin -2,维采宁 2,新西兰牡荆苷

RAAS Endocrinology/Hormones
Vicenin 2 来源于广金钱草 (Desmodium styracifolium) 的地上部分。Vicenin 2 是一种血管紧张素转换酶 (ACE) 抑制剂,IC50=43.83 μM。
T3753 Sinapinic Acid

Sinapic acid,芥子酸,Synapoic acid

Apoptosis; RAAS; Reactive Oxygen Species; HDAC Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Endocrinology/Hormones; Immunology/Inflammation; Metabolism; NF-κB
Sinapinic Acid (Synapoic acid) 是从 Hydnophytum formicarumJack. 根中分离到的酚类,是HDAC 抑制剂,对ACE-I 的活性也有抑制作用。它有抗肿瘤活性,诱导肿瘤细胞凋亡,具有抗氧化、抗糖尿病的作用。
T6627 Phosphoramidon Disodium

Phosphoramidon Disodium Salt,磷酰胺二钠

RAAS; Neprilysin; Others Endocrinology/Hormones; Metabolism; Others
Phosphoramidon Disodium (Phosphoramidon Disodium Salt) Salt 是一种金属蛋白酶 (metalloprotease) 抑制剂 。Phosphoramidon Disodium Salt 抑制内皮素转化酶 (ECE) ,中性肽内切酶 (NEP) 和血管紧张素转换酶 (ACE) 的IC50分别为 3.5 ,0.034 和 78 μM。
TN7109 Prosaikogenin G

RAAS Endocrinology/Hormones
Prosaikogenin G 是一种从柴胡的根中分离出的化合物,是 Saikosaponin d 在胃肠道中的衍生物。Prosaikogenin G 对 Angiotensin II 诱导的大鼠系膜细胞增殖具有明显的抑制作用,同时对肾脏有保护作用。
T6S0657 Isorhynchophylline

IsoRhy,异钩藤碱,Isorhyncophylline,Isorhychophylline,7-Isorhyncophylline

Others Others
Isorhynchophylline (7-Isorhyncophylline) 是一种分离自钩藤中的生物碱类化合物,具有舒张血管、降血压、保护神经免于局部缺血造成损伤的作用。
TN2295 Vicenin-1

Vicenin -1

Antioxidant; Angiotensin-converting Enzyme (ACE) Metabolism; oxidation-reduction
Vicenin-1 (Vicenin -1) 是一种来自豆科植物胡卢巴种子中分离出来的类黄酮糖苷,具有强大的抗炎和抗氧化活性,抑制血管紧张素转换酶 (ACE) 。
T0522 Diammonium Glycyrrhizinate

甘草酸二铵,Glycyrrhizin

Dehydrogenase Metabolism
Diammonium Glycyrrhizinate (Glycyrrhizin) 是分离自甘草中的化合物,有抗炎作用。
TCS1704 Artemitin

艾黄素,Artemetin,Artemisetin,Erianthin

Antioxidant oxidation-reduction
Artemitin (Erianthin) 是一种存在于翼齿六棱菊中的天然黄酮,具有抗氧化、抗炎、抗病毒活性。
TN1464 Camellianin A

Apoptosis; RAAS Apoptosis; Endocrinology/Hormones
Camellianin A 是从 A. nitida 和 茶叶中提取得到的类黄酮列化合物,具有抗癌活性,抑制血管紧张素转换酶 (ACE) 活性,促进 Hep G2 和 MCF-7 细胞凋亡。Camellianin A 可预防CCl4-通过施加抗氧化应激、抗炎和抗细胞凋亡诱导肝损伤。
T2836 Isorhamnetin

3-methylquercetin,3'-Methylquercetin,Isorhamnetol,异鼠李素,3'-Methoxyquercetin

MEK; PI3K; Endogenous Metabolite MAPK; Metabolism; PI3K/Akt/mTOR signaling
Isorhamnetin (3-methylquercetin) 是从中草药沙棘中提取的一种类黄酮,可通过抑制MEK1和PI3K 来抑制皮肤癌。
T37298 Spinacine

Endogenous Metabolite Metabolism
Spinacine 是人内源性代谢产物。
T38649 Lyciumin A

Others Others
Lyciumin A, a cyclic octapeptide, possesses inhibitory properties against proteases, renin, and angiotensin-converting enzyme. It holds potential for hypertension research.
T38481 Camellianin B

Others Others
Camellianin B, a flavonoid compound and metabolite of Camellianin A, exhibits antioxidant properties and acts as an angiotensin converting enzyme (ACE) inhibitor.
TN4103 Ganoderic acid K

Ganoderic acid K is an angiotensin-converting enzyme inhibitor. It has anti-tumor, and anti-inflammatory activities.
TN2045 Pelargonidin-3-O-glucoside chloride

Others; Estrogen/progestogen Receptor Endocrinology/Hormones; Others
Pelargonidin-3-O-glucopyranoside is the glucoside of Pelargonidin, an potential antidiabetic agent. Pelargonidin-3-O-glucopyranoside has antioxidant, anti-inflammatory, anti-estrogenic, and angiotensin-converting enzyme inhibitory activities.
T19911 Rescinnamine

Anaprel,Apoterin S,Apoterin

Others Others
Rescinnamine is an inhibitor of angiotensin-converting enzyme. It also is a vinca alkaloid obtained from Rauwolfia serpentina and other species of Rauwolfia. It used as an antihypertensive drug.
T19186 Aldosterone

Others Others
Aldosterone is the primary mineralocorticoid. Aldosterone is synthesized and secreted in response to renin-angiotensin system activation or high dietary potassium by the zona glomerulosa of the adrenal cortex.
TN1060 Ganoderol A

灵芝醇 A,灵芝醇A

Others Others
Ganoderol A has significant anti-inflammatory activity and protection against UVA damage. it has an inhibitory effect on angiotensin converting enzyme activity and cholesterol biosynthesis.
TN5645 Isomartynoside

Isomartynoside has inhibition against the angiotensin converting enzyme (ACE) activities, the IC 50 value is 505±26.7μg/ml, it may have antihypertensive effect. Isomartynoside also shows obvious anti-fatigue activity.
T38593 1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone

Others Others
Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone9, a quinolone alkaloid derived from Evodia rutaecarpa, is a potent antagonist of the angiotensin II receptor, displaying an IC50 value of 48.2 μM.
T81229 Safflor yellow B

Safflor yellow B 通过抑制血管紧张素 II 介导的人脐静脉细胞损伤,调节 Bcl-2/p22 (phox) 表达,展现出神经保护作用。
TN2487 1,3,5,6-Tetrahydroxyxanthone

Others Others
1,3,5,6-Tetrahydroxyxanthone shows moderate hepatoprotective activity with EC(50) values of 160.2 +/- 0.6 microM against tacrine-induced cytotoxicity in HepG2 cells. It can inhibit angiotensin-I-converting-enzyme activity in a dose-dependent manner.
TN4860 Pueroside B

COX; PPAR DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Neuroscience
Pueroside B may can treat coronary heart disease, it can interact with two or more targets[peroxisome proliferator activated receptor γ (PPAR-γ), angiotensin-converting enzyme (ACE), hydroxymethylglutaryl coenzyme A receptor (HMGR), cyclooxygenase-2 (COX2
TN4431 Leucosceptoside A

RAAS; PKC Chromatin/Epigenetic; Cytoskeletal Signaling; Endocrinology/Hormones
Leucosceptoside A shows inhibitory activity against PKCalpha with the IC50 value of 19.0 microM; it also exhibits strong inhibitory capacity against α-glucosidase. Leucosceptoside A has antihypertensive effect, it shows angiotensin converting enzyme (ACE)
TN1061 Ganoderol B

Androgen Receptor Endocrinology/Hormones
Ganoderol B is a potent β ±-glucosidase and angiotensin-converting enzyme inhibitor, with an IC(50) of β ±-glucosidase is 119.8 uM. It may be useful in prostate cancer and benign prostatic hyperplasia (BPH) therapy through suppressing the function of andr
T79958 Isocrenatoside

Angiotensin-converting Enzyme (ACE) Metabolism
Isocrenatoside (compound 6)为环状八肽,具有ACE抑制活性。该化合物可通过乙醇提取Microtoena prainiana茎部分离纯化。研究显示,1 mg/mL浓度下,Isocrenatoside的ACE抑制效率高达99.3%。
T75697 1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone

Others Others
1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone,为喹诺酮类生物碱,作用为二酰基甘油酰基转移酶抑制剂与血管紧张素II受体阻断剂,其IC50值依次为20.1 μM与34.1 μM。此化合物亦展现对幽门螺杆菌的有效抗活性,MIC值达10 μg/mL。
TN1104 Cyanidin 3-sambubioside chloride

Cyanidin-3-O-sambubioside chloride

RAAS; Antioxidant; NO Synthase Endocrinology/Hormones; Immunology/Inflammation; oxidation-reduction
Cyanidin 3-sambubioside chloride (Cyanidin-3-O-sambubioside chloride) 是一种从植物中提取的花青素,是一种 NO和 H274Y 突变的抑制剂,对流感神经氨酸酶具有抑制作用。Cyanidin 3-sambubioside chloride 具有抗氧化,抗血管生成和抗病毒活性,抑制血管紧张素转换酶 (ACE) 的活性,可用于研究病毒感染和心血管疾病。

天然产物

Angiotensin II human
Cat.No: T7040
Synonym: DRVYIHPF,Angiotensin II,Hypertensin II,血管紧张素Ⅱ,Ang II,血管紧张素II
Target: Apoptosis, RAAS
Peimisine
Cat.No: T5S0106
Synonym: 贝母辛,Ebeiensine
Target: RAAS, AChR
Vicenin 3
Cat.No: T13299
Synonym: 维采宁-3,维采宁 3
Target: RAAS
Deserpidine
Cat.No: T8270
Synonym: 地舍平,Harmonyl
Target: RAAS
Plantainoside D
Cat.No: T5796
Synonym: Isoplantamajoside,车前草苷D
Target: RAAS, PKC
Lisinopril
Cat.No: T21418
Synonym: Linopril,赖诺普利,Zestril,Prinivil,Lisipril
Target: RAAS
Vicenin 2
Cat.No: T3851
Synonym: Vicenin -2,维采宁 2,新西兰牡荆苷
Target: RAAS
Sinapinic Acid
Cat.No: T3753
Synonym: Sinapic acid,芥子酸,Synapoic acid
Target: Apoptosis, RAAS, Reactive Oxygen Species, HDAC
Phosphoramidon Disodium
Cat.No: T6627
Synonym: Phosphoramidon Disodium Salt,磷酰胺二钠
Target: RAAS, Neprilysin, Others
Prosaikogenin G
Cat.No: TN7109
Synonym:
Target: RAAS
Isorhynchophylline
Cat.No: T6S0657
Synonym: IsoRhy,异钩藤碱,Isorhyncophylline,Isorhychophylline,7-Isorhyncophylline
Target: Others
Vicenin-1
Cat.No: TN2295
Synonym: Vicenin -1
Target: Antioxidant, Angiotensin-converting Enzyme (ACE)
Diammonium Glycyrrhizinate
Cat.No: T0522
Synonym: 甘草酸二铵,Glycyrrhizin
Target: Dehydrogenase
Artemitin
Cat.No: TCS1704
Synonym: 艾黄素,Artemetin,Artemisetin,Erianthin
Target: Antioxidant
Camellianin A
Cat.No: TN1464
Synonym:
Target: Apoptosis, RAAS
Isorhamnetin
Cat.No: T2836
Synonym: 3-methylquercetin,3'-Methylquercetin,Isorhamnetol,异鼠李素,3'-Methoxyquercetin
Target: MEK, PI3K, Endogenous Metabolite
Spinacine
Cat.No: T37298
Synonym:
Target: Endogenous Metabolite
Lyciumin A
Cat.No: T38649
Synonym:
Target: Others
Camellianin B
Cat.No: T38481
Synonym:
Target: Others
Ganoderic acid K
Cat.No: TN4103
Synonym:
Target:
Pelargonidin-3-O-glucoside chloride
Cat.No: TN2045
Synonym:
Target: Others, Estrogen/progestogen Receptor
Rescinnamine
Cat.No: T19911
Synonym: Anaprel,Apoterin S,Apoterin
Target: Others
Aldosterone
Cat.No: T19186
Synonym:
Target: Others
Ganoderol A
Cat.No: TN1060
Synonym: 灵芝醇 A,灵芝醇A
Target: Others
Isomartynoside
Cat.No: TN5645
Synonym:
Target:
1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone
Cat.No: T38593
Synonym:
Target: Others
Safflor yellow B
Cat.No: T81229
Synonym:
Target:
1,3,5,6-Tetrahydroxyxanthone
Cat.No: TN2487
Synonym:
Target: Others
Pueroside B
Cat.No: TN4860
Synonym:
Target: COX, PPAR
Leucosceptoside A
Cat.No: TN4431
Synonym:
Target: RAAS, PKC
Ganoderol B
Cat.No: TN1061
Synonym:
Target: Androgen Receptor
Isocrenatoside
Cat.No: T79958
Synonym:
Target: Angiotensin-converting Enzyme (ACE)
1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone
Cat.No: T75697
Synonym:
Target: Others
Cyanidin 3-sambubioside chloride
Cat.No: TN1104
Synonym: Cyanidin-3-O-sambubioside chloride
Target: RAAS, Antioxidant, NO Synthase
Cat. No. Product Name Species Expression System
TMPY-02207 ACE2/ACEH Protein, Rat, Recombinant (His)

angiotensin I converting enzyme 2

Rat HEK293 Cells
ACE2/ACEH Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85 kDa and the accession number is Q5EGZ1.
TMPY-01838 ACE2/ACEH Protein, Mouse, Recombinant (His)

angiotensin I converting enzyme 2,2010305L05Rik

Mouse HEK293 Cells
ACE2/ACEH Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85 kDa and the accession number is Q8R0I0-1.
TMPY-03561 ACE2/ACEH Protein, Rhesus, Recombinant (hFc)

angiotensin I converting enzyme 2

Rhesus HEK293 Cells
ACE2/ACEH Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 110.7kDa and the accession number is B6DUF3.
TMPY-01839 ACE2/ACEH Protein, Mouse, Recombinant (His & hFc)

2010305L05Rik,angiotensin I converting enzyme 2

Mouse HEK293 Cells
ACE2/ACEH Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 112 kDa and the accession number is Q8R0I0-1.
TMPY-03830 ACE2/ACEH Protein, Rhesus, Recombinant (His)

angiotensin I converting enzyme 2

Rhesus HEK293 Cells
ACE2/ACEH Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85.1 kDa and the accession number is B6DUF3.
TMPH-02268 AGTR2 Protein, Human, Recombinant (His & SUMO)

AT2 receptor,Angiotensin II type-2 receptor,Type-2 ...

Human E. coli
Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.
TMPY-05725 ACE2/ACEH Protein, Human, Recombinant (His & Avi), Biotinylated

angiotensin I converting enzyme 2,ACEH

Human Baculovirus Insect Cells
ACE2/ACEH Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in Baculovirus insect cells with His and Avi tag. The predicted molecular weight is 86.86 kDa and the accession number is Q9BYF1-1.
TMPY-06334 ACE2/ACEH Protein, Human, Recombinant (hFc), Biotinylated

ACEH,angiotensin I converting enzyme 2

Human HEK293 Cells
ACE2/ACEH Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 110.3 kDa and the accession number is NP_068576.1.
TMPJ-00386 ACE2/ACEH Protein, Human, Recombinant (HEK293, His & Avi), Biotinylated

Metalloprotease MPROT15,ACEH,Angiotensin-Converting...

Human HEK293 Cells
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate...
TMPY-05696 ACE2/ACEH Protein, Human, Recombinant (His), Biotinylated

ACEH,angiotensin I converting enzyme 2

Human HEK293 Cells
ACE2/ACEH Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85.1 kDa and the accession number is Q9BYF1-1.
TMPY-00655 ACE2/ACEH Protein, Human, Recombinant (hFc)

angiotensin I converting enzyme 2,ACEH

Human HEK293 Cells
ACE2/ACEH Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 110.3 kDa and the accession number is Q9BYF1-1.
TMPY-04312 ACE2/ACEH Protein, Human, Recombinant (mFc)

angiotensin I converting enzyme 2,ACEH

Human HEK293 Cells
ACE2/ACEH Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 110 kDa and the accession number is Q9BYF1-1.
TMPY-05266 ACE2/ACEH Protein, Human, Recombinant (His)

ACEH,angiotensin I converting enzyme 2

Human HEK293 Cells
ACE2/ACEH Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85.1 kDa and the accession number is Q9BYF1-1.
TMPH-03081 ACE2 Protein, Paguma larvata, Recombinant (hFc)

EC:3.4.17.23,Angiotensin-converting enzyme 2,ACE-re...

Paguma larvata HEK293 Cells
ACE2 Protein, Paguma larvata, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 112.7 kDa and the accession number is Q56NL1.
TMPH-02267 AGTRAP Protein, Human, Recombinant (His & Myc & SUMO)

ATRAP,AT1 receptor-associated protein,Type-1 angiotensin...

Human E. coli
Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity.
TMPH-01739 NLRP3 Protein, Human, Recombinant (His)

PYRIN-containing APAF1-like protein 1,Caterpiller protein 1....

Human E. coli
NLRP3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 27.7 kDa and the accession number is Q96P20.
TMPY-01232 Angiotensinogen Protein, Human, Recombinant (His)

SERPINA8,angiotensinogen (serpin peptidase inhibito...

Human HEK293 Cells
Angiotensinogen Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.2 kDa and the accession number is B0ZBE2.
TMPY-02232 Angiotensinogen Protein, Mouse, Recombinant (His)

AngI,Serpina8,angiotensinogen (serpin peptidase inh...

Mouse HEK293 Cells
Angiotensinogen Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.8 kDa and the accession number is P11859.
TMPY-04501 Angiotensinogen Protein, Rat, Recombinant (His)

angiotensinogen (serpin peptidase inhibitor, clade ...

Rat HEK293 Cells
Angiotensinogen Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51 kDa and the accession number is A6KJ10.
TMPK-00383 ACE2/ACEH Protein, Human, Recombinant (His & Avi)

ACE2,ACE-2,ACEH

Human HEK293 Cells
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. A...
TMPY-02869 MMP-12 Protein, Human, Recombinant (catalytic domain)

HME,ME,MMP-12,MME,matrix metallopeptidase 12

Human E. coli
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Macrophage Metalloelastase, also known as Matrix metalloproteinase-12, Macrophage elastase, ...
TMPK-00552 ACE2/ACEH Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated

ACEH,ACE-2,ACE2

Cynomolgus HEK293 Cells
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. A...
TMPK-00551 ACE2/ACEH Protein, Cynomolgus, Recombinant (His & Avi)

ACE-2,ACEH,ACE2

Cynomolgus HEK293 Cells
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. A...
TMPK-00382 ACE2/ACEH Protein, Human, Recombinant (hFc & Avi), Biotinylated

ACE-2,ACE2,ACEH

Human HEK293 Cells
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. A...
TMPY-02574 Chymase 1 Protein, Human, Recombinant (His)

MCT1,chymase 1, mast cell,chymase,CYH

Human Baculovirus Insect Cells
The STR polymorphism in the CMA1 gene is associated with asthma and that this association is even stronger with atopic asthma. CMA1 and IL-4 in atopic asthma and for IL-4 in atopy in general. The local angiotensin II system (LAS) has numerous functions, including the regulation of growth and differentiation in the gastrointestinal tract. Angiotensin II (AngII) may be generated by angiotensin-I-converting enzyme (ACE) or mast cell chymase (CMA1) and plays an important role in inflammatory process...
TMPH-02778 Mcpt4 Protein, Mouse, Recombinant (E. coli, His)

MSMCP,Mast cell protease 4,Myonase,Serosal mast cell proteas...

Mouse E. coli
Has chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4-|-Ile-5' bond of angiotensin I and the 'Phe-20-|-Ala-21' bond of amyloid beta-protein, and is less active towards the 'Phe-8-|-His-9' bond of angiotensin I and the 'Phe-4-|-Ala-5' and 'Tyr-10-|-Glu-11' bonds of amyloid beta-protein. Involved in thrombin regulation and fibronectin processing. Mcpt4 Protein, Mouse, Recombinant (E. c...
TMPH-01041 Carboxypeptidase A6 Protein, Human, Recombinant (His & SUMO)

CPAH,CPA6,Carboxypeptidase A6

Human E. coli
May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas. May convert inactive angiotensin I into the biologically active angiotensin II. Releases a C-terminal amino acid, with preference for large hydrophobic C-terminal amino acids and shows only very weak activity toward small amino acids and histidine. Carboxypeptidase A6 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular w...
TMPH-03352 KLKB1 Protein, Rat, Recombinant (His)

Fletcher factor,Klkb1,Plasma prekallikrein,Kininogenin,Plasm...

Rat P. pastoris (Yeast)
The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. KLKB1 Protein, Rat, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 29.8 kDa and the accession number is P14272.
TMPK-00438 SARS-COV-2 Spike S Trimer Protein (His & Avi)

COVID-19,S protein,S glycoprotein,Spike glycoprotein

SARS-CoV-2 HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike S Trimer Protein (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 136.6 kDa and the accession number i...
TMPK-00432 SARS-COV-2 Spike S1 Protein (hFc & Avi)

Spike protein S1,S glycoprotein Subunit1,S1 protein,Spike,S1...

SARS-CoV-2 HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike S1 Protein (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 102.6 kDa and the accession number is A0A6...
TMPK-00434 SARS-COV-2 Spike RBD Protein (hFc & Avi), Biotinylated

S protein RBD,S glycoprotein RBD,Spike protein RBD

SARS-CoV-2 HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike RBD Protein (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 51.7 kDa and the accession ...
TMPK-00911 SARS Spike RBD Protein (His & Avi)

S protein RBD,Spike protein RBD,S glycoprotein RBD

SARS HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS Spike RBD Protein (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27.9 kDa and the accession number is P59594.
TMPH-02881 Renin-2 Protein, Mouse, Recombinant (His)

Ren2,Renin-2,Submandibular gland renin,Angiotensino...

Mouse E. coli
Renin is a highly specific endopeptidase, related to pepsin, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. Its function in the salivary gland is not understood. Renin-2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.0 kDa and the accession number ...
TMPK-00908 SARS Spike S1 Protein (hFc & Avi)

Spike protein S1,S1 protein,Spike,S1 protein,S glycoprotein ...

SARS HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS Spike S1 Protein (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 100.6 kDa and the accession number is P59594.
TMPK-00913 SARS Spike S1 Protein (His & Avi), Biotinylated

Spike protein S1,S glycoprotein Subunit1,S1 protein,Spike,S1...

SARS HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS Spike S1 Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 75.9 kDa and the accession number ...
TMPK-00440 SARS-COV-2 Spike S1 Protein (His & Avi), Biotinylated

S1 protein,S glycoprotein Subunit1,Spike,S1 protein,Spike pr...

SARS-CoV-2 HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike S1 Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 77.9 kDa and the accession n...
TMPK-00909 SARS Spike S1 Protein (hFc & Avi), Biotinylated

Spike protein S1,S glycoprotein Subunit1,Spike,S1 protein,S1...

SARS HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS Spike S1 Protein (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 100.6 kDa and the accession number...
TMPK-00442 SARS-COV-2 (Omicron B.1.1.529) Spike S Trimer Protein (His & Avi), Biotinylated

S glycoprotein,COVID-19,S protein,Spike glycoprotein

SARS-CoV-2 HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 (Omicron B.1.1.529) Spike S Trimer Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 13...
TMPK-00439 SARS-COV-2 Spike RBD Protein (His & Avi), Biotinylated

S protein RBD,S glycoprotein RBD,Spike protein RBD

SARS-CoV-2 HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike RBD Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27 kDa and the accession nu...
TMPK-00912 SARS Spike RBD Protein (His & Avi), Biotinylated

S glycoprotein RBD,S protein RBD,Spike protein RBD

SARS HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS Spike RBD Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27.9 kDa and the accession number...
TMPK-00441 SARS-COV-2 Spike S Trimer Protein (His & Avi), Biotinylated

Spike glycoprotein,S glycoprotein,S protein,COVID-19

SARS-CoV-2 HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike S Trimer Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 136.6 kDa and the acce...
TMPK-00443 SARS-COV-2 (Omicron B.1.1.529) Spike S1 Protein (His & Avi), Biotinylated

Spike,S1 protein,S glycoprotein Subunit1,S1 protein,Spike pr...

SARS-CoV-2 HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 (Omicron B.1.1.529) Spike S1 Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 77.94 kD...
TMPH-03106 Coagulation factor XII Protein, Pig, Recombinant (His)

HAF,Hageman factor,F12,Coagulation factor XII

Sus scrofa (Pig) E. coli
Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa. Coagulation factor XII Protein, Pig, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predic...
TMPK-00444 SARS-COV-2 Spike S1 NTD Protein (His & Flag)

S1 protein NTD,Spike glycoprotein Subunit1 NTD,S glycoprotei...

SARS-CoV-2 HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike S1 NTD Protein (His & Flag) is expressed in HEK293 mammalian cells with C-His-Flag tag. The predicted molecular weight is 35 kDa and the accession number is A...
TMPK-00910 SARS Spike S1 Protein (His & Avi)

S1 protein,S glycoprotein Subunit1,Spike protein S1,Spike,S1...

SARS HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS Spike S1 Protein (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 75.9 kDa and the accession number is P59594.
TMPK-00437 SARS-COV-2 Spike RBD Protein (His & Avi)

S glycoprotein RBD,Spike protein RBD,S protein RBD

SARS-CoV-2 HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike RBD Protein (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27 kDa and the accession number is A0A6G7...
TMPK-00433 SARS-COV-2 Spike S1 Protein (hFc & Avi), Biotinylated

S1 protein,Spike,S1 protein,Spike protein S1,S glycoprotein ...

SARS-CoV-2 HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike S1 Protein (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 102.6 kDa and the accession ...
TMPH-03351 KLKB1 Protein, Rat, Recombinant (E. coli, His)

Plasma prekallikrein,Klkb1,Kininogenin,Plasma kallikrein,Fle...

Rat E. coli
The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. KLKB1 Protein, Rat, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.8 kDa and the accession number is P14272.
TMPJ-00964 PRCP Protein, Human, Recombinant (His)

PCP,Proline Carboxypeptidase,PRCP,Lysosomal Pro-X Carboxypep...

Human HEK293 Cells
Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP is detected in many tissues, with highest levels observed in placenta, lung, and liver. It is also present in the heart, brain, pancreas, and kidney. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH. PRCP has been s...
TMPY-03269 Prolyl Endopeptidase Protein, Mouse, Recombinant (His)

PEP,AI450383,AI047692,D10Wsu136e,prolyl endopeptidase,Pop

Mouse Baculovirus Insect Cells
Prolyl endopeptidase, also known as PREP, belongs to a distinct class of serine peptidases. It is a large cytosolic enzyme which was first described in the cytosol of rabbit brain as an oligopeptidase. Prolyl endopeptidase degrades the nonapeptide bradykinin at the Pro-Phe bond. It is involved in the maturation and degradation of peptide hormones and neuropeptides such as alpha-melanocyte-stimulating hormone, luteinizing hormone-releasing hormone (LH-RH), thyrotropin-releasing hormone, angiotens...
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重组蛋白

ACE2/ACEH Protein, Rat, Recombinant (His)
Cat.No: TMPY-02207
Species: Rat
Expression System: HEK293 Cells
ACE2/ACEH Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01838
Species: Mouse
Expression System: HEK293 Cells
ACE2/ACEH Protein, Rhesus, Recombinant (hFc)
Cat.No: TMPY-03561
Species: Rhesus
Expression System: HEK293 Cells
ACE2/ACEH Protein, Mouse, Recombinant (His & hFc)
Cat.No: TMPY-01839
Species: Mouse
Expression System: HEK293 Cells
ACE2/ACEH Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-03830
Species: Rhesus
Expression System: HEK293 Cells
AGTR2 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-02268
Species: Human
Expression System: E. coli
ACE2/ACEH Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05725
Species: Human
Expression System: Baculovirus Insect Cells
ACE2/ACEH Protein, Human, Recombinant (hFc), Biotinylated
Cat.No: TMPY-06334
Species: Human
Expression System: HEK293 Cells
ACE2/ACEH Protein, Human, Recombinant (HEK293, His & Avi), Biotinylated
Cat.No: TMPJ-00386
Species: Human
Expression System: HEK293 Cells
ACE2/ACEH Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05696
Species: Human
Expression System: HEK293 Cells
ACE2/ACEH Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00655
Species: Human
Expression System: HEK293 Cells
ACE2/ACEH Protein, Human, Recombinant (mFc)
Cat.No: TMPY-04312
Species: Human
Expression System: HEK293 Cells
ACE2/ACEH Protein, Human, Recombinant (His)
Cat.No: TMPY-05266
Species: Human
Expression System: HEK293 Cells
ACE2 Protein, Paguma larvata, Recombinant (hFc)
Cat.No: TMPH-03081
Species: Paguma larvata
Expression System: HEK293 Cells
AGTRAP Protein, Human, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-02267
Species: Human
Expression System: E. coli
NLRP3 Protein, Human, Recombinant (His)
Cat.No: TMPH-01739
Species: Human
Expression System: E. coli
Angiotensinogen Protein, Human, Recombinant (His)
Cat.No: TMPY-01232
Species: Human
Expression System: HEK293 Cells
Angiotensinogen Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02232
Species: Mouse
Expression System: HEK293 Cells
Angiotensinogen Protein, Rat, Recombinant (His)
Cat.No: TMPY-04501
Species: Rat
Expression System: HEK293 Cells
ACE2/ACEH Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00383
Species: Human
Expression System: HEK293 Cells
MMP-12 Protein, Human, Recombinant (catalytic domain)
Cat.No: TMPY-02869
Species: Human
Expression System: E. coli
ACE2/ACEH Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00552
Species: Cynomolgus
Expression System: HEK293 Cells
ACE2/ACEH Protein, Cynomolgus, Recombinant (His & Avi)
Cat.No: TMPK-00551
Species: Cynomolgus
Expression System: HEK293 Cells
ACE2/ACEH Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPK-00382
Species: Human
Expression System: HEK293 Cells
Chymase 1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02574
Species: Human
Expression System: Baculovirus Insect Cells
Mcpt4 Protein, Mouse, Recombinant (E. coli, His)
Cat.No: TMPH-02778
Species: Mouse
Expression System: E. coli
Carboxypeptidase A6 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01041
Species: Human
Expression System: E. coli
KLKB1 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03352
Species: Rat
Expression System: P. pastoris (Yeast)
SARS-COV-2 Spike S Trimer Protein (His & Avi)
Cat.No: TMPK-00438
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-COV-2 Spike S1 Protein (hFc & Avi)
Cat.No: TMPK-00432
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-COV-2 Spike RBD Protein (hFc & Avi), Biotinylated
Cat.No: TMPK-00434
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS Spike RBD Protein (His & Avi)
Cat.No: TMPK-00911
Species: SARS
Expression System: HEK293 Cells
Renin-2 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02881
Species: Mouse
Expression System: E. coli
SARS Spike S1 Protein (hFc & Avi)
Cat.No: TMPK-00908
Species: SARS
Expression System: HEK293 Cells
SARS Spike S1 Protein (His & Avi), Biotinylated
Cat.No: TMPK-00913
Species: SARS
Expression System: HEK293 Cells
SARS-COV-2 Spike S1 Protein (His & Avi), Biotinylated
Cat.No: TMPK-00440
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS Spike S1 Protein (hFc & Avi), Biotinylated
Cat.No: TMPK-00909
Species: SARS
Expression System: HEK293 Cells
SARS-COV-2 (Omicron B.1.1.529) Spike S Trimer Protein (His & Avi), Biotinylated
Cat.No: TMPK-00442
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-COV-2 Spike RBD Protein (His & Avi), Biotinylated
Cat.No: TMPK-00439
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS Spike RBD Protein (His & Avi), Biotinylated
Cat.No: TMPK-00912
Species: SARS
Expression System: HEK293 Cells
SARS-COV-2 Spike S Trimer Protein (His & Avi), Biotinylated
Cat.No: TMPK-00441
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-COV-2 (Omicron B.1.1.529) Spike S1 Protein (His & Avi), Biotinylated
Cat.No: TMPK-00443
Species: SARS-CoV-2
Expression System: HEK293 Cells
Coagulation factor XII Protein, Pig, Recombinant (His)
Cat.No: TMPH-03106
Species: Sus scrofa (Pig)
Expression System: E. coli
SARS-COV-2 Spike S1 NTD Protein (His & Flag)
Cat.No: TMPK-00444
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS Spike S1 Protein (His & Avi)
Cat.No: TMPK-00910
Species: SARS
Expression System: HEK293 Cells
SARS-COV-2 Spike RBD Protein (His & Avi)
Cat.No: TMPK-00437
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-COV-2 Spike S1 Protein (hFc & Avi), Biotinylated
Cat.No: TMPK-00433
Species: SARS-CoV-2
Expression System: HEK293 Cells
KLKB1 Protein, Rat, Recombinant (E. coli, His)
Cat.No: TMPH-03351
Species: Rat
Expression System: E. coli
PRCP Protein, Human, Recombinant (His)
Cat.No: TMPJ-00964
Species: Human
Expression System: HEK293 Cells
Prolyl Endopeptidase Protein, Mouse, Recombinant (His)
Cat.No: TMPY-03269
Species: Mouse
Expression System: Baculovirus Insect Cells
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Cat. No. Product Name Target Signaling Pathways
T11870 Losartan D4

氯沙坦 D4,DuP-753 D4

Others Others
Losartan D4, the deuterium-labeled version of Losartan, functions as an angiotensin II receptor antagonist. It inhibits the interaction between angiotensin II and AT1 receptors by competing for binding, achieving an IC50 value of 20 nM.
T11193 Enalaprilat-d5 sodium

MK-422 D5 Sodium Salt,依那普利拉钠 D5,Enalaprilat D5 Sodium Salt

Others Others
Enalaprilat D5 Sodium Salt is the deuterium labeled Enalaprilat, which is an angiotensin-converting enzyme (ACE) inhibitor.
T11675 Irbesartan-d4

厄贝沙坦 D4,SR-47436 D4,BMS-186295 D4

Others Others
Irbesartan D4, a deuterium-labeled variant of Irbesartan, is a highly potent and specific antagonist of the angiotensin II type 1 (AT1) receptor.
T11192 Enalapril D5 maleate

MK-421 D5 maleate,马来酸依那普利D5

Others Others
Enalapril D5 maleate is deuterium labeled Enalapril, which is an angiotensin converting enzyme (ACE) inhibitor.
T11194 Enalaprilat D5

MK-422 D5,依那普利拉 D5

Others Others
Enalaprilat D5 is the deuterium labeled Enalaprilat, which is an angiotensin-converting enzyme (ACE) inhibitor.
TMIJ-0185 Telmisartan-13C-d3

Telmisartan-13C-d3 是 Telmisartan 的 13C 和氘代化合物。Telmisartan 的 CAS 号为 144701-48-4。Telmisartan 是一种血管紧张素II 1型受体拮抗剂,能够抑制其活性,IC50值为 9.2 nM。
T13196 Trandolaprilate D5

Trandolaprilat D5,RU 44403 D5

Others Others
Trandolaprilate D5 is a deuterium-labeled Trandolaprilate. Trandolaprilate is an inhibitor of angiotensin-converting enzyme (ACE).
T11869 Losartan (D4 Carboxylic Acid)

E-3174 D4,氯沙坦羧酸 D4,EXP-3174 D4

Others Others
Losartan D4 Carboxylic Acid is the deuterium labeled Losartan, which is an angiotensin II receptor antagonist.
T10440 Azilsartan-d5

TAK-536 D5

Others Others
Azilsartan (TAK-536) D5 is the deuterium-labeled Azilsartan. Azilsartan is a specific antagonist of the angiotensin II type 1 receptor.
T12300 Olmesartan-d4

RNH-6270 D4,奥美沙坦 D4

Others Others
Olmesartan D4 is the deuterium labeled Olmesartan. Olmesartan is an antagonist of angiotensin II receptor (AT1R) used to treat high blood pressure.
T13282 Valsartan-d9

CGP-48933 D9,缬沙坦 D9

Others Others
Valsartan D9 is a deuterium-labeled valsartan. Valsartan is an antagonist of the angiotensin II receptor and for the treatment of high blood pressure and heart failure.
T10670 Candesartan-d4

坎地沙坦 D4,CV-11974 D4

Others Others
Candesartan D4 is the deuterium labeled Candesartan. Candesartan is an antagonist of angiotensin II receptor.
T71065 Quinapril-d5

Quinapril-d5 is intended for use as an internal standard for the quantification of quinapril by GC- or LC-MS. Quinapril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor quinaprilat. In vivo, quinapril reduces mean arterial pressure in renal hypertensive and spontaneously hypertensive rats. It inhibits angiotensin I-induced pressor responses in normotensive rats and dogs. Quinapril prevents left ventricular heart failure in CHF 14.6 cardiomyopathic hamsters. Formulations con...
T13195 Trandolapril D5

RU44570 D5

Others Others
Trandolapril D5 is a deuterium labeled Trandolapril. Trandolapril is an orally active inhibitor of angiotensin converting enzyme (ACE) for hypertension and congestive heart failure (CHF).
T71205 Fosinopril-d7 sodium salt

Fosinopril-d7 is intended for use as an internal standard for the quantification of fosinopril by GC- or LC-MS. Fosinopril is a prodrug form of the angiotensin-converting enzyme inhibitor fosinoprilat. Oral administration of fosinopril inhibits angiotensin I-induced pressor responses in normotensive rats, dogs, and monkeys when administered at doses of 15, 15, and 10 µmol/kg, respectively. Fosinopril reduces fractional shortening and decreases left ventricular size in a porcine model of congesti...
TMIJ-0176 Perindopril-d4

Perindopril-d4 是 Perindopril 的氘代化合物。Perindopril 的 CAS 号为 95153-31-4。Perindoprilat 是一种血管紧张素转换酶抑制剂。
TMIJ-0177 Perindoprilat-d4

Perindoprilat-d4 是 Perindoprilat 的氘代化合物。Perindoprilat 的 CAS 号为 95153-31-4。Perindoprilat 是一种血管紧张素转换酶抑制剂。
TMIJ-0131 rac-Valsartan-d9

rac-Valsartan-d9 是 rac-Valsartan 的氘代化合物。rac-Valsartan 的 CAS 号为 137862-53-4。Valsarta 是一种血管紧张素 II 受体拮抗剂,有用于高血压和心力衰竭的研究潜力。
TMIJ-0317 Nadolol-d9 (Mixture of Diastereomers)

Nadolol-d9 (Mixture of Diastereomers) 是 Nadolol 的氘代化合物。Nadolol 的 CAS 号为 42200-33-9。Nadolol 是一种有机阴离子转运多肽 1A2 (OATP1A2) 的底物,是一种非选择性的、具有口服活性的 β-肾上腺素受体 (β-adrenergic receptors) 阻滞剂,可用于高血压,心绞痛和血管性头痛的研究。
TMIJ-0253 Benazepril-d5 HCl

Benazepril-d5 HCl 是 Benazepril HCl 的氘代化合物。Benazepril HCl 的 CAS 号为 86541-74-4。Benazepril hydrochloride 是一种血管紧张素转化酶(ACE)抑制剂,能够作用于高血压。
TMID-0241 Olmesartan-d6 Acid

Olmesartan-d6 Acid 是 Olmesartan Acid 的氘代化合物。Olmesartan Acid 的 CAS 号为 144689-24-7。Olmesartan 是一种血管紧张素II受体 (AT1R) 拮抗剂,常用于研究高血压。
T70883 Moexipril-d5

Moexipril-d5 intended for use as an internal standard for the quantification of moexipril by GC- or LC-MS. Moexipril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor moexiprilat. It is converted to moexiprilat in vivo by side chain ester hydrolysis. Moexipril inhibits ACE in a cell-free assay (IC50 = 2.7 µM for the rabbit enzyme). It also inhibits phosphodiesterase 4 (IC50s = 38, 160, and 230 µM for PDE4B2, PDE4A5 and PDE4D5, respectively). Moexipril (0.1-30 mg/kg per day) ...

同位素标记化合物

Losartan D4
Cat.No: T11870
Synonym: 氯沙坦 D4,DuP-753 D4
Target: Others
Enalaprilat-d5 sodium
Cat.No: T11193
Synonym: MK-422 D5 Sodium Salt,依那普利拉钠 D5,Enalaprilat D5 Sodium Salt
Target: Others
Irbesartan-d4
Cat.No: T11675
Synonym: 厄贝沙坦 D4,SR-47436 D4,BMS-186295 D4
Target: Others
Enalapril D5 maleate
Cat.No: T11192
Synonym: MK-421 D5 maleate,马来酸依那普利D5
Target: Others
Enalaprilat D5
Cat.No: T11194
Synonym: MK-422 D5,依那普利拉 D5
Target: Others
Telmisartan-13C-d3
Cat.No: TMIJ-0185
Synonym:
Target:
Trandolaprilate D5
Cat.No: T13196
Synonym: Trandolaprilat D5,RU 44403 D5
Target: Others
Losartan (D4 Carboxylic Acid)
Cat.No: T11869
Synonym: E-3174 D4,氯沙坦羧酸 D4,EXP-3174 D4
Target: Others
Azilsartan-d5
Cat.No: T10440
Synonym: TAK-536 D5
Target: Others
Olmesartan-d4
Cat.No: T12300
Synonym: RNH-6270 D4,奥美沙坦 D4
Target: Others
Valsartan-d9
Cat.No: T13282
Synonym: CGP-48933 D9,缬沙坦 D9
Target: Others
Candesartan-d4
Cat.No: T10670
Synonym: 坎地沙坦 D4,CV-11974 D4
Target: Others
Quinapril-d5
Cat.No: T71065
Synonym:
Target:
Trandolapril D5
Cat.No: T13195
Synonym: RU44570 D5
Target: Others
Fosinopril-d7 sodium salt
Cat.No: T71205
Synonym:
Target:
Perindopril-d4
Cat.No: TMIJ-0176
Synonym:
Target:
Perindoprilat-d4
Cat.No: TMIJ-0177
Synonym:
Target:
rac-Valsartan-d9
Cat.No: TMIJ-0131
Synonym:
Target:
Nadolol-d9 (Mixture of Diastereomers)
Cat.No: TMIJ-0317
Synonym:
Target:
Benazepril-d5 HCl
Cat.No: TMIJ-0253
Synonym:
Target:
Olmesartan-d6 Acid
Cat.No: TMID-0241
Synonym:
Target:
Moexipril-d5
Cat.No: T70883
Synonym:
Target:
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