BovinePeripheralMyelinProtein P2 (53-78) is a derivative composed of amino acid residues 53 to 78 from the peripheralmyelin P2 protein of bovine origin. It acts as a T cell epitope and is used to induce experimental autoimmune neuritis (EAN) in Lewis rats.
[Sar9,Met(O2)11]-Substance P TFA is a selective tachykinin NK1 receptor agonist.[Sar9,Met(O2)11]-Substance P and septide (10-100 pmol per rat, i.c.v.) are equipotent in increasing mean arterial blood pressure (MAP) and heart rate (HR), yet they have dissi
Galanin (2-11) amide is a synthetic peptide fragment of the neuropeptide galanin and an agonist of the galanin-2 (GAL2) receptor (EC50= 9.32 nM in a fluorescence imaging plate reader assay).1It selectively binds to the GAL2receptor (IC50= 1.76 nM for the rat receptor) over the GAL1receptor (IC50= 879 nM for the human receptor) but does also bind to the GAL3receptor (Ki= 271 nM for the rat receptor).1,2Intracerebroventricular administration of galanin (2-11) amide (1 nmol/animal) decreases immobility in the forced swim test in rats.3It also reduces the hind paw mechanical pain threshold and increases the hind paw cold sensitivity threshold in rats.1
Tyrosinase-related Protein 2 (TRP-2) (181-188) is a peptide derived from the tyrosinase-related protein 2 (TRP-2), specifically corresponding to residues 180-188. It is the primary epitope within TRP-2 that is recognized by anti-B16 CTLs. Moreover, It is a peptide that conforms to the binding motif of the MHC class I H2-Kb.
PeripheralMyelin P0 Protein (180-199), derived from mice, is a purified component of the myelin found in the peripheral nerves. This protein serves as a neuritogenic peptide, initiating the growth of neuronal processes.