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153

抑制剂 & 化合物

39

天然产物

2

化合物库

254

重组蛋白

1

同位素标记化合物

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Cat. No. Product Name
L2200 酪氨酸激酶分子库

1016 compounds
1016 种酪氨酸激酶抑制剂的独特集合,可用于高通量筛选和高内涵筛选;
L9410 共价抑制剂库

1920 compounds
1920 种小分子的独特集合,包含已发现的共价抑制剂以及包含某些共价反应基团常见弹头的分子,如氯乙酰基,2-氯丙酰基,丙烯酰基,1-丙-2-炔基,1-丁-2-炔基,酮羰基,二硫键等,可以用于共价抑制剂药物研发;

化合物库

酪氨酸激酶分子库
Cat.No: L2200
Compounds: 1016
共价抑制剂库
Cat.No: L9410
Compounds: 1920
Cat. No. Product Name Target Signaling Pathways
T41099 EGFR Protein Tyrosine Kinase Substrate

EGFR Protein Tyrosine Kinase Substrate is a EGFR protein tyrosine kinase substrate.
TP1269 Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9)

Tyrosine Protein Kinase JAK2 Phospho-Tyr8, 9

Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9) is a peptide derived from mouse JAK2, specifically composed of amino acids 475 to 491.
T2314 PF-431396

FAK; PYK2 Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
PF 431396 是一种具有口服活性的 FAK (IC50:2 nM) 和 Pyk2 (IC50:11 nM)的抑制剂。
T5480 BI-4464

FAK; Ligands for Target Protein for PROTAC Angiogenesis; Cytoskeletal Signaling; PROTAC; Tyrosine Kinase/Adaptors
BI-4464 是一种高选择性的 ATP 竞争性 PTK2/FAK 抑制剂,IC50=17 nM。它可用于PROTAC 降解剂的 PTK2 配体。
T6997 SU6656

FAK; Akt; Src Angiogenesis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
SU6656 是Src 家族激酶抑制剂,抑制 Src,Yes,Lyn,Fyn 的IC50分别为 280,20,130,170 nM。它还能抑制p-AKT。它可抑制FAK Y576/577、 Y925、Y861位点的磷酸化。
T9576 AMP-945

FAK Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
AMP-945 是一种粘着斑激酶抑制剂。
T9973 FAK-IN-7

FAK Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
FAK-IN-7 有潜在的抗增殖活性,是一种 FAK 抑制剂。
T6177 PF-562271 besylate

PF-00562271 Besylate

FAK; PYK2; CDK Angiogenesis; Cell Cycle/Checkpoint; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
PF-562271 besylate (PF-00562271 Besylate) 是一种可逆的,有效的,ATP 竞争性的 FAK(IC50:1.5 nM)和 Pyk2 (IC50:13 nM)激酶抑制剂。
T2465 PF-562271

PF562271,PF 562271

FAK; PYK2; CDK Angiogenesis; Cell Cycle/Checkpoint; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
PF-562271 是一种可逆的,有效的,ATP 竞争性的 FAK (IC50:1.5 nM)和 Pyk2 (IC50:13 nM)激酶抑制剂。
T2001 PF-573228

PF 573228

Apoptosis; FAK Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
PF-573228是一种选择性的 FAK 抑制剂,对 FAK 纯化重组催化片段的 IC50值为4 nM。
T1835 Ibrutinib

伊布替尼,依鲁替尼,PCI-32765

Tyrosine Kinases; Src; BTK; Ligands for Target Protein for PROTAC Angiogenesis; PROTAC; Tyrosine Kinase/Adaptors
Ibrutinib (PCI-32765) 是一种布鲁顿酪氨酸激酶 (BTK) 抑制剂 (IC50=0.5 nM),具有不可逆性和选择性。Ibrutinib 可以阻断 BTK 抑制 B 细胞的增殖和存活,具有抗肿瘤活性,可以用于治疗慢性淋巴细胞白血病等。
T2655 CEP-37440

CEP37440

FAK; ALK Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
CEP-37440 是一种新型的 FAK (IC50:2.3 nM) 和 ALK (IC50:120 nM) 双重抑制剂。
T3041 ALK inhibitor 2

FAK; ALK Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
ALK inhibitor 2 是嘧啶类 ALK 的有效抑制剂。它是一种睾丸特异性丝氨酸/苏氨酸激酶 2 (TSSK2;IC50=37 nM) 和粘着斑激酶 (FAK;IC50=5 nM) 抑制剂。
T1918 NVP-TAE 226

TAE226

Apoptosis; FAK; c-Met/HGFR; PYK2; IGF-1R Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
NVP-TAE 226 (TAE226) 是一种具有 ATP 竞争性的双重FAK 和IGF-1R 抑制剂,IC50分别为 5.5 nM、140 nM。它还抑制Pyk2、胰岛素受体,IC50分为 3.5 nM、40 nM。
T21768 PF-562271 hydrochloride

PF-562271 HCl

FAK; PYK2; CDK Angiogenesis; Cell Cycle/Checkpoint; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
PF-562271 hydrochloride (PF-562271 HCl) 是一种可逆的,有效的,ATP 竞争性的 FAK (IC50:1.5 nM)和 Pyk2 (IC50:13 nM)激酶抑制剂。
T10285 ALK inhibitor 1

FAK; IGF-1R; ALK Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
ALK inhibitor 1 是嘧啶类 ALK 的有效抑制剂。它是一种睾丸特异性丝氨酸/苏氨酸激酶 2 (TSSK2;IC50=31 nM) 和粘着斑激酶 (FAK;IC50=2 nM) 抑制剂。
T4337 PCI 29732

PCI29732,PCI-29732

Others; BCRP; BTK Angiogenesis; Membrane transporter/Ion channel; Others; Tyrosine Kinase/Adaptors
PCI 29732 是一种有效的可逆BTK 抑制剂,对 BTK、Lck 和 Lyn 的Kiapp 值分别为 8.2、4.6 和 2.5 nM。它通过竞争性结合ABCG2 的 ATP 结合位点来抑制ABCG2的功能。
T2281 GSK2256098

GSK 2256098,GSK-2256098,GTPL7939

Apoptosis; FAK Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
GSK2256098 (GTPL7939) 是一种选择性FAK 激酶抑制剂,抑制胰腺癌细胞的生长和存活。
T7541 PTP inhibitor 1

PTP Inhibitor II,alpha-溴-4-甲氧基苯乙酮

Phosphatase Metabolism
PTP inhibitor 1 是蛋白酪氨酸磷酸酶 (PTP) 抑制剂,具有抗血管生成作用。
T2066 Quizartinib

AC220,奎扎替尼

Apoptosis; FLT; Autophagy; Ligands for Target Protein for PROTAC Angiogenesis; Apoptosis; Autophagy; PROTAC; Tyrosine Kinase/Adaptors
Quizartinib (AC220) 是一种第二代 Ⅱ 型 FLT3 酪氨酸激酶抑制剂,具有口服活性和高选择性,抑制 FLT3-WT 和 FLT3-ITD 自磷酸化 (IC50=4.1/1.1 nM)。Quizartinib 可以诱导肿瘤细胞凋亡。
T1996 Defactinib

PF-04554878,VS-6063

FAK Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
Defactinib (VS-6063) 是新型的 FAK 抑制剂,能够时间和剂量依赖性的抑制 FAK 在 Tyr397 位点磷酸化。
T0827 Cefsulodin sodium

Cefsulodine sodium,Sulcephalosporin,头孢磺啶钠

Antibacterial; Antibiotic Microbiology/Virology
Cefsulodin sodium (Sulcephalosporin) 是β内酰胺抗生素,对缘脓杆菌和肠杆菌有活性。
T4636 Protein kinase inhibitors 1

Others; DYRK Cell Cycle/Checkpoint; Others; Tyrosine Kinase/Adaptors
Protein kinase inhibitors 1 是新型的 HIPK2 抑制剂,其 IC50=74 nM,Kd=9.5 nM。
T0263 Chloropyramine hydrochloride

Nilfan,盐酸氯吡胺,Alergosan,Halopyramine hydrochloride

FAK; VEGFR; Histamine Receptor Angiogenesis; Cytoskeletal Signaling; GPCR/G Protein; Immunology/Inflammation; Neuroscience; Tyrosine Kinase/Adaptors
Chloropyramine hydrochloride (Alergosan) 是一种组胺受体 H1 拮抗剂,可抑制VEGFR-3和FAK 的生化功能。
T24730 Roslin 2 bromide

Roslin-2,Benzylhexamethylenetetramine bromide,Roslin2

FAK; p53 Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
Roslin 2 bromide (Benzylhexamethylenetetramine bromide) 是一种 p53 再激活剂,可破坏 FAK 和 p53 的结合。 Roslin 2 bromide 具有抗癌作用。
T2609 Masitinib

AB1010,马赛替尼

Apoptosis; FAK; c-Fms; FGFR; Bcr-Abl; PDGFR; Src; c-Kit; Hck Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
Masitinib (AB1010) 是生物口服可利用的选择性 c-Kit 抑制剂 (对于人重组c-Kit,IC50=200 nM),它还抑制PDGFRα/β(IC50s=540/800 nM),Lyn(对 LynB 的IC50=510 nM),Lck,较小程度上抑制FGFR3和FAK。它有抗增殖,促凋亡活性,且毒性低。
T4185 lavendustin C

HDBA,NSC 666251,N-(2,5-二羟基苄基)-5-氨基水杨酸

CaMK; EGFR; Tyrosinase; Src Angiogenesis; JAK/STAT signaling; Neuroscience; Proteases/Proteasome; Tyrosine Kinase/Adaptors
lavendustin C (NSC 666251) 是 Ca2+钙调蛋白依赖性激酶 II 抑制剂,IC50为 0.2 µM。它抑制 EGFR 相关酪氨酸激酶和 pp60c-src(+)激酶,IC50分别为 0.012 和 0.5 µM。
T1950 PND-1186

PND1186,PND 1186,VS-4718,SR-2516

Apoptosis; FAK Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
PND-1186 (VS-4718) 是一种高特异性的FAK 可逆抑制剂,IC50为 1.5 nM。它选择性促进肿瘤细胞凋亡。
T7119 Y15

1,2,4,5-苯四胺四盐酸盐,1,2,4,5-Benzenetetramine tetrahydrochlor,FAK Inhibitor 14

FAK Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
Y15 (1,2,4,5-Benzenetetramine tetrahydrochlor) 是一种特异性的粘着斑激酶抑制剂,能够降低其自身磷酸化活性,抑制癌细胞的活力,阻断肿瘤生长。
T2160 Suramin Sodium Salt

苏拉明钠,BAY-205,Suramin hexasodium salt,苏拉明钠盐,NF-060

Apoptosis; Phosphatase; SARS-CoV; Sirtuin; Reverse Transcriptase; Topoisomerase; Parasite Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
Suramin Sodium Salt (BAY-205) 是可逆的竞争性蛋白酪氨酸磷酸酶抑制剂。它抑制 IP5K,是抗寄生虫,抗肿瘤和抗血管生成剂。它是sirtuins 的有效抑制剂,也是 SARS-CoV-2 RNA 依赖性 RNA 聚合酶抑制剂。
T21761 HNMPA

IGF-1R Tyrosine Kinase/Adaptors
HNMPA 是膜不可渗透的胰岛素受体酪氨酸激酶 (insulin receptor tyrosine kinase) 抑制剂。HNMPA 可以抑制人胰岛素受体的酪氨酸和丝氨酸自磷酸化。HNMPA 对环 AMP 依赖性蛋白激酶或蛋白激酶 C 活性没有影响。
T31458 DiFMUP

6,8-Difluoro-4-methylumbelliferyl phosphate

DiFMUP (6,8-Difluoro-4-methylumbelliferyl phosphate) 是一种荧光底物,抑制蛋白酪氨酸磷酸酶(PTPs),可用于检测苏氨酸磷酸酶的活性。
T7381 TCS 401

Phosphatase Metabolism
TCS 401 是一种选择性的蛋白酪氨酸磷酸酶 1B 抑制剂。
T12578 (E,E)-RAMB4

PTP1B-IN-8

Phosphatase Metabolism
PTP1B-IN-8 is a potent and selective inhibitor of protein tyrosine phosphatase-1B (PTP1B).
T7900 BAY-474

c-Met/HGFR Tyrosine Kinase/Adaptors
BAY-474 是酪氨酸蛋白激酶 c-MET 抑制剂,能够用于表观遗传学探针。
T7356 PTP1B-IN-1

PTP1B inhibitor,5-苯基-1,2,5-噻二唑烷-3-酮 1,1-二氧化物

Phosphatase Metabolism
PTP1B-IN-1 (PTP1B inhibitor) 是一种蛋白质酪氨酸磷酸酶 1B 的有效抑制剂 (IC50 : 1.6 mM)
T4256 PTP1B-IN-2

Phosphatase Metabolism
PTP1B-IN-2 是一种蛋白酪氨酸磷酸酶抑制剂,IC50=50 nM。
TP1051L Protein Kinase C Peptide Substrate acetate

Protein Kinase C Peptide Substrate acetate(120253-69-2 free base)

Others Others
Protein Kinase C Peptide Substrate acetate(120253-69-2 free base) 以依赖于第二信使和特定衔接蛋白的方式靶向特定细胞间隔物,以响应激活 g 蛋白偶联受体、酪氨酸激酶受体或酪氨酸激酶偶联受体的细胞外信号。
T4511 ST271

ST 271

Phospholipase; Tyrosine Kinases Metabolism; Tyrosine Kinase/Adaptors
ST271 是蛋白质酪氨酸激酶 (PTK) 抑制剂,抑制 fMet-Leu-Phe 和 PAF 引起的 phospholipase D 活化的IC50值分别为 6.7 和 9 μM。
T7101 Tyrphostin AG30

Tyrphostin AG30(AG30),酪氨酸磷酸化抑制剂 AG 30

EGFR; Tyrosine Kinases Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Tyrphostin AG30 (AG30) 是一种有效的蛋白质酪氨酸激酶 (PTK) 抑制剂,选择性地抑制 c-ErbB 的自我更新诱导,并能抑制原发性红细胞 c-ErbB 激活 STAT5。
T13013 Sodium stibogluconate

Stibogluconate trisodium nonahydrate,葡萄糖酸锑钠

Phosphatase Metabolism
Sodium stibogluconate (Stibogluconate trisodium nonahydrate) 是一种有效的蛋白酪氨酸磷酸酶 (phosphatase) 抑制剂。 它在10,100 和 100 μg/mL 时分别抑制 99% 的 SHP-1,SHP-2 和 PTP1B 活性。
T19498 p-Cresyl sulfate potassium

p-Tolyl sulfate potassium salt,p-Cresol sulfate potassium,p-Methylphenyl potassium sulfate,对甲基硫酸钾,Potassium p-tolyl sulfate

Endogenous Metabolite Metabolism
p-Cresyl sulfate potassium (p-Tolyl sulfate potassium salt) 是一种尿毒症毒素,能够与原型蛋白质结合。
T14841 BVT948

Phosphatase; P450; Histone Methyltransferase Chromatin/Epigenetic; Metabolism
BVT948 是一种蛋白酪氨酸磷酸酶抑制剂,还可以抑制赖氨酸甲基转移酶 SETD8 (KMT5A) 和几种细胞色素 P450 (P450) 同工型。
T67893 PTP1B-IN-22

Phosphatase Metabolism
PTP1B-IN-22是一种蛋白酪氨酸磷酸酶1B (PTP1B)抑制剂,可抑制骨骼肌 L6肌管的葡萄糖摄取。
T3211 Midostaurin

米哚妥林,N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251,苯甲酰基十字孢碱

Others; PKC Chromatin/Epigenetic; Cytoskeletal Signaling; Others
Midostaurin (PKC412) 是一种多靶点蛋白激酶抑制剂,有抗肿瘤活性,对 PKCα/β/γ、Syk、Flk-1、Akt、PKA、c-Kit、c-Fgr、c-Src、FLT3、PDFRβ和VEGFR1/2的IC50值范围为 22 到500 nM 之间。
T10190 7-BIA

Phosphatase Metabolism
7-BIA 是一种受体型蛋白酪氨酸磷酸酶 D (PTPRD) 抑制剂,具有抗抗成瘾作用,可用于研究神经性疼痛。
T6217 LFM-A13

PLK; JAK; BTK Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
LFM-A13 是一种 BTK,JAK2,PLK 有效抑制剂,可抑制 BTK、Plx1 和 PLK3 的活性,IC50分别为 2.5、10 和 61 μM。
T50088 N-phenylthiophene-2-carboximidamide

Others Others
N-phenylthiophene-2-carboximidamide 是一种噻吩衍生物,可以作为蛋白酪氨酸激酶(PTKs)的抑制剂和 G 蛋白偶联受体(GPCR)的配体发挥作用。
T37184 CX08005

2-[(2-tetradecoxyphenyl)carbamoyl]benzoic acid

Phosphatase Metabolism
CX08005 是一种蛋白酪氨酸磷酸酶 1B 抑制剂,可减轻与非酒精性脂肪肝相关的肝脏脂质蓄积和微循环障碍。
T1962 ASP3026

ASP 3026

Apoptosis; ALK Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
ASP3026 是一种选择性的,具有口服活性的间变性淋巴瘤激酶抑制剂,可诱导肿瘤细胞凋亡,可研究非小细胞肺癌。

化合物

EGFR Protein Tyrosine Kinase Substrate
Cat.No: T41099
Synonym:
Target:
Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9)
Cat.No: TP1269
Synonym: Tyrosine Protein Kinase JAK2 Phospho-Tyr8, 9
Target:
PF-431396
Cat.No: T2314
Synonym:
Target: FAK, PYK2
BI-4464
Cat.No: T5480
Synonym:
Target: FAK, Ligands for Target Protein for PROTAC
SU6656
Cat.No: T6997
Synonym:
Target: FAK, Akt, Src
AMP-945
Cat.No: T9576
Synonym:
Target: FAK
FAK-IN-7
Cat.No: T9973
Synonym:
Target: FAK
PF-562271 besylate
Cat.No: T6177
Synonym: PF-00562271 Besylate
Target: FAK, PYK2, CDK
PF-562271
Cat.No: T2465
Synonym: PF562271,PF 562271
Target: FAK, PYK2, CDK
PF-573228
Cat.No: T2001
Synonym: PF 573228
Target: Apoptosis, FAK
Ibrutinib
Cat.No: T1835
Synonym: 伊布替尼,依鲁替尼,PCI-32765
Target: Tyrosine Kinases, Src, BTK, Ligands for Target Protein for PROTAC
CEP-37440
Cat.No: T2655
Synonym: CEP37440
Target: FAK, ALK
ALK inhibitor 2
Cat.No: T3041
Synonym:
Target: FAK, ALK
NVP-TAE 226
Cat.No: T1918
Synonym: TAE226
Target: Apoptosis, FAK, c-Met/HGFR, PYK2, IGF-1R
PF-562271 hydrochloride
Cat.No: T21768
Synonym: PF-562271 HCl
Target: FAK, PYK2, CDK
ALK inhibitor 1
Cat.No: T10285
Synonym:
Target: FAK, IGF-1R, ALK
PCI 29732
Cat.No: T4337
Synonym: PCI29732,PCI-29732
Target: Others, BCRP, BTK
GSK2256098
Cat.No: T2281
Synonym: GSK 2256098,GSK-2256098,GTPL7939
Target: Apoptosis, FAK
PTP inhibitor 1
Cat.No: T7541
Synonym: PTP Inhibitor II,alpha-溴-4-甲氧基苯乙酮
Target: Phosphatase
Quizartinib
Cat.No: T2066
Synonym: AC220,奎扎替尼
Target: Apoptosis, FLT, Autophagy, Ligands for Target Protein for PROTAC
Defactinib
Cat.No: T1996
Synonym: PF-04554878,VS-6063
Target: FAK
Cefsulodin sodium
Cat.No: T0827
Synonym: Cefsulodine sodium,Sulcephalosporin,头孢磺啶钠
Target: Antibacterial, Antibiotic
Protein kinase inhibitors 1
Cat.No: T4636
Synonym:
Target: Others, DYRK
Chloropyramine hydrochloride
Cat.No: T0263
Synonym: Nilfan,盐酸氯吡胺,Alergosan,Halopyramine hydrochloride
Target: FAK, VEGFR, Histamine Receptor
Roslin 2 bromide
Cat.No: T24730
Synonym: Roslin-2,Benzylhexamethylenetetramine bromide,Roslin2
Target: FAK, p53
Masitinib
Cat.No: T2609
Synonym: AB1010,马赛替尼
Target: Apoptosis, FAK, c-Fms, FGFR, Bcr-Abl, PDGFR, Src, c-Kit, Hck
lavendustin C
Cat.No: T4185
Synonym: HDBA,NSC 666251,N-(2,5-二羟基苄基)-5-氨基水杨酸
Target: CaMK, EGFR, Tyrosinase, Src
PND-1186
Cat.No: T1950
Synonym: PND1186,PND 1186,VS-4718,SR-2516
Target: Apoptosis, FAK
Y15
Cat.No: T7119
Synonym: 1,2,4,5-苯四胺四盐酸盐,1,2,4,5-Benzenetetramine tetrahydrochlor,FAK Inhibitor 14
Target: FAK
Suramin Sodium Salt
Cat.No: T2160
Synonym: 苏拉明钠,BAY-205,Suramin hexasodium salt,苏拉明钠盐,NF-060
Target: Apoptosis, Phosphatase, SARS-CoV, Sirtuin, Reverse Transcriptase, Topoisomerase, Parasite
HNMPA
Cat.No: T21761
Synonym:
Target: IGF-1R
DiFMUP
Cat.No: T31458
Synonym: 6,8-Difluoro-4-methylumbelliferyl phosphate
Target:
TCS 401
Cat.No: T7381
Synonym:
Target: Phosphatase
(E,E)-RAMB4
Cat.No: T12578
Synonym: PTP1B-IN-8
Target: Phosphatase
BAY-474
Cat.No: T7900
Synonym:
Target: c-Met/HGFR
PTP1B-IN-1
Cat.No: T7356
Synonym: PTP1B inhibitor,5-苯基-1,2,5-噻二唑烷-3-酮 1,1-二氧化物
Target: Phosphatase
PTP1B-IN-2
Cat.No: T4256
Synonym:
Target: Phosphatase
Protein Kinase C Peptide Substrate acetate
Cat.No: TP1051L
Synonym: Protein Kinase C Peptide Substrate acetate(120253-69-2 free base)
Target: Others
ST271
Cat.No: T4511
Synonym: ST 271
Target: Phospholipase, Tyrosine Kinases
Tyrphostin AG30
Cat.No: T7101
Synonym: Tyrphostin AG30(AG30),酪氨酸磷酸化抑制剂 AG 30
Target: EGFR, Tyrosine Kinases
Sodium stibogluconate
Cat.No: T13013
Synonym: Stibogluconate trisodium nonahydrate,葡萄糖酸锑钠
Target: Phosphatase
p-Cresyl sulfate potassium
Cat.No: T19498
Synonym: p-Tolyl sulfate potassium salt,p-Cresol sulfate potassium,p-Methylphenyl potassium sulfate,对甲基硫酸钾,Potassium p-tolyl sulfate
Target: Endogenous Metabolite
BVT948
Cat.No: T14841
Synonym:
Target: Phosphatase, P450, Histone Methyltransferase
PTP1B-IN-22
Cat.No: T67893
Synonym:
Target: Phosphatase
Midostaurin
Cat.No: T3211
Synonym: 米哚妥林,N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251,苯甲酰基十字孢碱
Target: Others, PKC
7-BIA
Cat.No: T10190
Synonym:
Target: Phosphatase
LFM-A13
Cat.No: T6217
Synonym:
Target: PLK, JAK, BTK
N-phenylthiophene-2-carboximidamide
Cat.No: T50088
Synonym:
Target: Others
CX08005
Cat.No: T37184
Synonym: 2-[(2-tetradecoxyphenyl)carbamoyl]benzoic acid
Target: Phosphatase
ASP3026
Cat.No: T1962
Synonym: ASP 3026
Target: Apoptosis, ALK
Cat. No. Product Name Target Signaling Pathways
TN1433 Batatasin III

FAK; Others; Akt Angiogenesis; Cytoskeletal Signaling; Others; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
Batatasin III 通过抑制上皮间质转化和 FAK-AKT 信号来抑制癌症迁移和侵袭,并具有抗癌活性。 Batatasin III 对整株生长有长期抑制作用,显示出抑制萌发活性。
T5S0761 Nitidine chloride

Apoptosis; ERK; FAK; p38 MAPK; NF-κB; Topoisomerase; STAT; Parasite Angiogenesis; Apoptosis; Cytoskeletal Signaling; DNA Damage/DNA Repair; JAK/STAT signaling; MAPK; Microbiology/Virology; NF-κB; Stem Cells; Tyrosine Kinase/Adaptors
Nitidine chloride 是从Zanthoxylum nitidum (Roxb) DC 中分离得到的,具有抗疟疾活性。它通过多个靶点通路,起抗癌作用,抑制STAT3、DNA 拓扑异构酶1和2A、ERK 和c-Src/FAK 相关信号通路。它通过MAPK 和NF-kB 途径抑制Lps 诱导的炎性细胞因子的产生。
T3122 Fangchinoline

Tetrandrine B,防己诺林碱,(+)-Limacine,Hanfangichin B,防己醇灵,(+)-Fangchinoline

Apoptosis; FAK; HIV Protease; Autophagy Angiogenesis; Apoptosis; Autophagy; Cytoskeletal Signaling; Microbiology/Virology; Proteases/Proteasome; Tyrosine Kinase/Adaptors
Fangchinoline (Tetrandrine B) 是从Stephaniatetrandra 中分离出来的,一种具有广泛生物学活性的天然产物。它是新型HIV-1抑制剂,通过损害 gp160 蛋白水解过程来抑制 HIV-1 复制。它靶向Focal adhesion kinase (FAK)并抑制肿瘤细胞中 FAK 介导的的信号传导途径。
T1695 DL-O-Tyrosine

Amino Acids and Derivatives Metabolism
DL-O-Tyrosine 是苯丙氨酸的代谢物,是形成儿茶酚胺的前体。它被用作β-地中海贫血中蛋白质氧化损伤的生物标志物。
TN1096 Ginsenoside Ra1

人参皂苷 Ra1,人参皂苷Ra1

Others; Tyrosine Kinases Others; Tyrosine Kinase/Adaptors
Ginsenoside Ra1 是来自人参的成分。 Ginsenoside Ra1 对缺氧/复氧诱导的蛋白酪氨酸激酶 (PTK) 活化具有显着抑制作用。
TN1053 Aloe-emodin-8-O-β-D-glucopyranoside

Aloe-emodin-8-O-beta-D-glucopyranoside,芦荟大黄素-8-O-β-D-葡萄糖苷

Phosphatase Metabolism
Aloe-emodin-8-O-β-D-glucopyranoside (Aloe-emodin-8-O-beta-D-glucopyranoside) 是一种分离自Saussrurea lappa 中的化合物,是一种温和的人类蛋白酪氨酸磷酸酶 1B 抑制剂,其IC50=26.6 μM。
T1737 Genistein

NPI 031L,三叶草,染料木素,金雀异黄酮

Apoptosis; EGFR; Endogenous Metabolite; Autophagy Angiogenesis; Apoptosis; Autophagy; JAK/STAT signaling; Metabolism; Tyrosine Kinase/Adaptors
Genistein (NPI 031L) 是一种大豆异黄酮,是一种多重的酪氨酸激酶抑制剂,通过改变细胞凋亡,细胞周期和血管生成以及抑制转移对多种癌症有化疗作用。
T6427 Butein

2’,3,4,4’-tetrahydroxy Chalcone,紫铆因

Apoptosis; EGFR; Others; PDE; Autophagy Angiogenesis; Apoptosis; Autophagy; JAK/STAT signaling; Metabolism; Others; Tyrosine Kinase/Adaptors
Butein (2’,3,4,4’-tetrahydroxy Chalcone) 是一种 cAMP 特异性PDE 抑制剂,也是蛋白酪氨酸激酶抑制剂,还是一种SIRT1激活剂。它通过 AKT 和 ERK/p38 MAPK 通路,靶向 FoxO3a 使 HeLa 细胞对 Cisplatin 敏感。
TN1470 Cassiaside B2

决明子苷B2

Phosphatase; MAO; 5-HT Receptor GPCR/G Protein; Metabolism; Neuroscience
Cassiaside B2 是蛋白酪氨酸磷酸酶1B (PTP1B) 和人单胺氧化酶A (hMAO-A) 的抑制剂。Cassiaside B2是 5-HT2C 受体的激动剂, 具有抗过敏活性。Cassiaside B2 是萘吡喃酮参比提取物(NRE)的有效成分之一。
TN1440 Beta-Hydroxyisovalerylshikonin

EGFR; Tyrosine Kinases; Prostaglandin Receptor; Src; AMPK; Fatty Acid Synthase Angiogenesis; Chromatin/Epigenetic; GPCR/G Protein; Immunology/Inflammation; JAK/STAT signaling; Metabolism; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
Beta-hydroxyisovalerylshikonin 是分离自Lithospermium radix 的天然产物,具有抑制PTK 的作用, 对 EGFR 和 v-Src 受体作用的IC50分别为 0.7 μM 和 1 μM。它对多种肿瘤细胞系均有抑制作用,可以高效诱导 NCI-H522 和 DMS114 细胞的死亡。
TN2019 Orobol

3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon,3',4',5,7-四羟基异黄酮

BCL; Caspase; PI3K Apoptosis; PI3K/Akt/mTOR signaling; Proteases/Proteasome
Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) 是酪氨酸特异性蛋白激酶和磷脂酰肌醇转换的抑制剂。Orobol 抑制 PI3K,对 PI3K α/β/γ/K/δ 的 IC50 为 3.46-5.27 μM。 Orobol 具有抗皮肤老化和抗肥胖的作用。
T0610 Piceatannol

白皮杉醇,trans-Piceatannol,Astringenin

Apoptosis; Serine/threonin kinase; PKA; Syk; PKC; Autophagy Angiogenesis; Apoptosis; Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism; Tyrosine Kinase/Adaptors
Piceatannol (Astringenin) 是一种Syk 抑制剂,可降低由 TNF 诱导的 iNOS 表达,可研究急性肺损伤。它是存在于各种水果和蔬菜中天然存在的多酚二苯乙烯,可诱导细胞自噬和凋亡,具有抗癌和抗炎特性。
TN2111 Prunin

Naringenin 7-0-glucoside,柚皮素-7-O-葡萄糖苷

Phosphatase; Anti-infection; Virus Protease Metabolism; Microbiology/Virology
Prunin (Naringenin 7-0-glucoside) 是一种人肠道病毒 A71 抑制剂。它抑制蛋白酪氨酸磷酸酶 1B,IC50值为 5.5 μM。
T4S0498 Glaucocalyxin A

蓝萼甲素,Wangzaozin B,Leukamenin F

Apoptosis; Akt; Caspase; PI3K Apoptosis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Proteases/Proteasome
Glaucocalyxin A (Leukamenin F) 是来自日本黑纹病菌的一种对映型月桂基二萜,具有抗肿瘤作用。它通过调节PI3K/Akt 信号通路抑制 GLI1 的核易位,诱导骨肉瘤凋亡。
T4S0878 Prunetin

樱黄素,Prunusetin

ERK; Dehydrogenase; NF-κB MAPK; Metabolism; NF-κB
Prunetin (Prunusetin) 是一种O-甲基化异黄酮,具有抗炎的作用。它是人醛脱氢酶的有效抑制剂。
T3S1612 kuwanon G

桑黄酮G,Moracenin B,桑黄酮 G,Kuwanone G

Phosphatase; Antibacterial; Bombesin Receptor; AChR; AChE; Glucosidase GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience
Kuwanon G (Moracenin B) 是一种从桑树中得到的黄酮类蛙皮素受体拮抗剂,具有杀菌作用。
TN5400 Aerugidiol

Aerugidiol inhibits protein tyrosine phosphatase 1B (PTP1B).
T20555 Glycyltyrosine

NSC 118362,Gly Tyr,NSC-118362,Gly-Tyr,NSC118362,N-Glycyl-L-tyrosine

Others Others
Glycyltyrosine, a dipeptide composed of tyrosine and glycine, is an incomplete breakdown product of protein catabolism or protein digestion.
T19885 Methyllucidone

Methyllucidone is an inhibitor of STAT3 that acts by regulating the expression of the protein tyrosine phosphatase MEG2.
TN3042 4-Hydroxycinnamamide

ATPase; EGFR; Potassium Channel; p38 MAPK; Calcium Channel; Sodium Channel; AMPK Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; MAPK; Membrane transporter/Ion channel; Metabolism; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases.
T39219 Ficusonolide

Others Others
Ficusonolide exhibits significant antidiabetic activity through its interactions with dipeptidyl peptidase-IV (DPP-IV), protein tyrosine phosphatase 1B (PTP-1B), α-glucosidase, and α-amylase.
T13740 Isotanshinone IIA

Others Others
Isotanshinone IIA, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM. is an abietane-type diterpene metabolite.
TN3335 Abyssinone V

Phosphatase Metabolism
Abyssinone V 是一种从刺桐茎皮中分离的天然化合物,是蛋白质酪氨酸磷酸酶 1B (PTP1B) 的抑制剂。
TN2887 3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid

Phosphatase Metabolism
(24E)-3,4-Seco-cucurbita-4,24-diene-3,26,29-trioic acid can inhibit the activity of protein tyrosine phosphatase 1B (PTP1B), with IC 50 values of 0.4uM.
T73073 PTP1B-IN-21

Others Others
PTP1B-IN-21 是蛋白酪氨酸磷酸酶 1B (PTP1B) 的选择性抑制剂 (IC50=1.56 μM),抑制力超出高度同源 T 细胞蛋白酪氨酸磷酸酶 (TCPTP;IC50>100 μM),PTP1B 是抑制 2 型糖尿病的重要靶点。
T38587 Chrysophanol triglucoside

Others Others
Chrysophanol triglucoside is an anthraquinone isolated from Cassia obtusifolia , inhibits protein tyrosine phosphatases 1B (PTP1B) and α-glucosidase with IC 50 s of 80.17 and 197.06 μM, respectively. Chrysophanol triglucoside has the potential for diabetes research.
TN3505 Beta-Peltoboykinolic acid

Phosphatase Metabolism
Beta-Peltoboykinolic acid has in vitro protein tyrosine phosphatase 1B (PTP1B) inhibitory, it inhibits PTP1B with IC50 values of 5.2+/-0.5 microM. It also has cytotoxic activity.
TN2913 3-Acetoxy-11-ursen-28,13-olide

Phosphatase Metabolism
3β-Acetoxy-urs-11-en-28,13-olide exhibits significant protein tyrosine phosphatase 1B (PTP1B) inhibitory activity, it is a mixed-type PTP1B inhibitor. It exhibits weak-moderate antiproliferative activity against the A2780 human ovarian cancer cell line.
T73072 PTP1B-IN-20

Others Others
PTP1B-IN-20 是蛋白酪氨酸磷酸酶 1B (PTP1B) 的选择性抑制剂 (IC50=1.05 μM),抑制力超出高度同源 T 细胞蛋白酪氨酸磷酸酶 (TCPTP;IC50=78.0 μM),PTP1B 是抑制 2 型糖尿病的重要靶点。
TN1775 Isocryptotanshinone

ERK; JNK; STAT JAK/STAT signaling; MAPK; Stem Cells
Isocryptotanshinone inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 56.1±6.3 μM, PTP1B acts as a negative regulator of insulin signaling, and selective inhibition of PTP1B has served as a potential drug target for the treatment of type 2 diabetes.
T3827 Rhein-8-glucoside calcium

大黄酸-8-O-β-D-葡萄糖苷,Rhein-8-O-β-D-glucopyranoside,Rhein-8-glucoside calcium salt

Phosphatase; Antibacterial Metabolism; Microbiology/Virology
Rhein-8-glucoside calcium (Rhein-8-glucoside calcium salt) salt 是一种从 Saussurea lappa 根的 EtOH 提取物中,分离得到的蒽醌类 hPTP1B 抑制剂,IC50值为11.5 μM,具有抗菌作用。
T38069 Aquastatin A

Others Others
Aquastatin A is a fungal metabolite originally isolated fromF. aquaeductuumthat has diverse biological activities.1It is active againstS. aureus(MIC = 32 μg/ml) and inhibits enoyl-acyl carrier protein reductase (Fabl; IC50= 3.2 μM) andS. aureusfatty acid synthesis (IC50= 3.5 μM).2Aquastatin A also inhibits the Na+/K+-ATPase and H+/K+-ATPase (IC50s = 7.1 and 6.2 μM, respectively), as well as protein tyrosine phosphatase 1B (PTP1B; IC50= 0.19 μM).1,3 1.Hamano, K., Kinoshita-Okami, M., Minagawa, K....
TN3525 Boehmenan

ERK; Phosphatase; EGFR; PARP; MEK; Wnt/beta-catenin; Akt; Caspase; STAT; p53 Angiogenesis; Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; JAK/STAT signaling; MAPK; Metabolism; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells; Tyrosine Kinase/Adaptors
(±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in a competitive manner. Boehmenan exhibits the potent cytotoxic effects against many cancer cell
T75495 Rubrofusarin 6-O-β-D-glucopyranoside

Others Others
Rubrofusarin 6-O-β-D-glucopyranoside为Rubrofusarin的糖苷形式,具有抑制蛋白酪氨酸磷酸酶 1B (PTP1B) 的活性,IC50值为87.36 μM,适用于糖尿病和抑郁症研究。
TN4279 Isoderrone

Tyrosinase Proteases/Proteasome
Isoderrone 在体外对α-葡萄糖苷酶(α-glucosidase)有抑制作用;它是一种蛋白酪氨酸磷酸酶1B(PTP1B)抑制剂,IC50值为22.7±1.7μM,表明它可能是一种治疗2型糖尿病的新药。
T79985 Cryptosporioptide A

Phosphatase Metabolism
Cryptosporioptide A (Compound 3)是一种从昆虫寄生真菌Cordyceps gracilioides中分离出的色素蛋白酪氨酸磷酸酶抑制剂,针对PTP1B、SHP2、CDC25B、LAR和SHP1等酶展示了抑制作用,其IC50值分别为7.3、5.7、7.6、>50、4.9 μg/mL。
TN2928 Pygenic acid A

3-Epicorosolic acid,脓毒酸A

3-Epicorosolic acid has a potent inhibitory effect on Epstein-Barr virus early antigen (EBV-EA) induction, it has potential anti-inflammatory activities as well as cancer chemopreventive activity.3-Epicorosolic acid shows both potent α-glucosidase and pro
T80007 Stevisalioside A

Phosphatase Metabolism
Stevisalioside A (Compound 2),一种从甜叶菊根提取的化合物,展现出抗糖尿病的口服活性。该化合物有效抑制PTP1B,IC50为526.8 μM,并能降低Stevisalioside A引起的高血糖小鼠血糖水平,改善餐后血糖峰值及口服葡萄糖和胰岛素耐量测试结果。
T36950 Rubrofusarin triglucoside

Others Others
Rubrofusarin triglucoside is a glycoside compound isolated from Cassia obtusifolia Linn seeds. Rubrofusarin triglucoside inhibits human monoamine oxidase A (hMAO-A) with an IC50 of 85.5 μM[1]. [1]. Pradeep Paudel, et al. Rubrofusarin as a Dual Protein Tyrosine Phosphate 1B and Human Monoamine Oxidase-A Inhibitor: An in Vitro and in Silico Study. ACS Omega. 2019 Jul 3;4(7):11621-11630.

天然产物

Batatasin III
Cat.No: TN1433
Synonym:
Target: FAK, Others, Akt
Nitidine chloride
Cat.No: T5S0761
Synonym:
Target: Apoptosis, ERK, FAK, p38 MAPK, NF-κB, Topoisomerase, STAT, Parasite
Fangchinoline
Cat.No: T3122
Synonym: Tetrandrine B,防己诺林碱,(+)-Limacine,Hanfangichin B,防己醇灵,(+)-Fangchinoline
Target: Apoptosis, FAK, HIV Protease, Autophagy
DL-O-Tyrosine
Cat.No: T1695
Synonym:
Target: Amino Acids and Derivatives
Ginsenoside Ra1
Cat.No: TN1096
Synonym: 人参皂苷 Ra1,人参皂苷Ra1
Target: Others, Tyrosine Kinases
Aloe-emodin-8-O-β-D-glucopyranoside
Cat.No: TN1053
Synonym: Aloe-emodin-8-O-beta-D-glucopyranoside,芦荟大黄素-8-O-β-D-葡萄糖苷
Target: Phosphatase
Genistein
Cat.No: T1737
Synonym: NPI 031L,三叶草,染料木素,金雀异黄酮
Target: Apoptosis, EGFR, Endogenous Metabolite, Autophagy
Butein
Cat.No: T6427
Synonym: 2’,3,4,4’-tetrahydroxy Chalcone,紫铆因
Target: Apoptosis, EGFR, Others, PDE, Autophagy
Cassiaside B2
Cat.No: TN1470
Synonym: 决明子苷B2
Target: Phosphatase, MAO, 5-HT Receptor
Beta-Hydroxyisovalerylshikonin
Cat.No: TN1440
Synonym:
Target: EGFR, Tyrosine Kinases, Prostaglandin Receptor, Src, AMPK, Fatty Acid Synthase
Orobol
Cat.No: TN2019
Synonym: 3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon,3',4',5,7-四羟基异黄酮
Target: BCL, Caspase, PI3K
Piceatannol
Cat.No: T0610
Synonym: 白皮杉醇,trans-Piceatannol,Astringenin
Target: Apoptosis, Serine/threonin kinase, PKA, Syk, PKC, Autophagy
Prunin
Cat.No: TN2111
Synonym: Naringenin 7-0-glucoside,柚皮素-7-O-葡萄糖苷
Target: Phosphatase, Anti-infection, Virus Protease
Glaucocalyxin A
Cat.No: T4S0498
Synonym: 蓝萼甲素,Wangzaozin B,Leukamenin F
Target: Apoptosis, Akt, Caspase, PI3K
Prunetin
Cat.No: T4S0878
Synonym: 樱黄素,Prunusetin
Target: ERK, Dehydrogenase, NF-κB
kuwanon G
Cat.No: T3S1612
Synonym: 桑黄酮G,Moracenin B,桑黄酮 G,Kuwanone G
Target: Phosphatase, Antibacterial, Bombesin Receptor, AChR, AChE, Glucosidase
Aerugidiol
Cat.No: TN5400
Synonym:
Target:
Glycyltyrosine
Cat.No: T20555
Synonym: NSC 118362,Gly Tyr,NSC-118362,Gly-Tyr,NSC118362,N-Glycyl-L-tyrosine
Target: Others
Methyllucidone
Cat.No: T19885
Synonym:
Target:
4-Hydroxycinnamamide
Cat.No: TN3042
Synonym:
Target: ATPase, EGFR, Potassium Channel, p38 MAPK, Calcium Channel, Sodium Channel, AMPK
Ficusonolide
Cat.No: T39219
Synonym:
Target: Others
Isotanshinone IIA
Cat.No: T13740
Synonym:
Target: Others
Abyssinone V
Cat.No: TN3335
Synonym:
Target: Phosphatase
3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid
Cat.No: TN2887
Synonym:
Target: Phosphatase
PTP1B-IN-21
Cat.No: T73073
Synonym:
Target: Others
Chrysophanol triglucoside
Cat.No: T38587
Synonym:
Target: Others
Beta-Peltoboykinolic acid
Cat.No: TN3505
Synonym:
Target: Phosphatase
3-Acetoxy-11-ursen-28,13-olide
Cat.No: TN2913
Synonym:
Target: Phosphatase
PTP1B-IN-20
Cat.No: T73072
Synonym:
Target: Others
Isocryptotanshinone
Cat.No: TN1775
Synonym:
Target: ERK, JNK, STAT
Rhein-8-glucoside calcium
Cat.No: T3827
Synonym: 大黄酸-8-O-β-D-葡萄糖苷,Rhein-8-O-β-D-glucopyranoside,Rhein-8-glucoside calcium salt
Target: Phosphatase, Antibacterial
Aquastatin A
Cat.No: T38069
Synonym:
Target: Others
Boehmenan
Cat.No: TN3525
Synonym:
Target: ERK, Phosphatase, EGFR, PARP, MEK, Wnt/beta-catenin, Akt, Caspase, STAT, p53
Rubrofusarin 6-O-β-D-glucopyranoside
Cat.No: T75495
Synonym:
Target: Others
Isoderrone
Cat.No: TN4279
Synonym:
Target: Tyrosinase
Cryptosporioptide A
Cat.No: T79985
Synonym:
Target: Phosphatase
Pygenic acid A
Cat.No: TN2928
Synonym: 3-Epicorosolic acid,脓毒酸A
Target:
Stevisalioside A
Cat.No: T80007
Synonym:
Target: Phosphatase
Rubrofusarin triglucoside
Cat.No: T36950
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPJ-00412 VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)

Vascular endothelial growth factor receptor 1,Vascular perme...

Human HEK293 Cells
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 is widely expressed in human tissues including normal lung, placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cellsand peripheral blood monocytes. VEGFR-1 contains seven Ig-like C2-type domains and one protein kinas...
TMPH-02271 BTK Protein, Human, Recombinant (His)

BPK,AGMX1,ATK,B-cell progenitor kinase,Tyrosine-

Human Baculovirus Insect Cells
Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in...
TMPY-04125 PTP1B Protein, Human, Recombinant (His)

protein tyrosine phosphatase, non-receptor...

Human E. coli
PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1B contains 1 tyrosine-protein p...
TMPJ-00778 HER2/ERBB2 Protein, Human, Recombinant (His)

TKR1,Metastatic lymph node gene 19 protein,ERBB2,Pr...

Human HEK293 Cells
HER2/ERBB2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 90-120 KDa and the accession number is P04626.
TMPY-03484 TCPTP Protein, Human, Recombinant

TCPTP,protein tyrosine phosphatase, non-re...

Human Baculovirus Insect Cells
TCPTP Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 36.8 kDa and the accession number is P17706-1.
TMPY-03548 PTPN12 Protein, Human, Recombinant

protein tyrosine phosphatase, non-receptor...

Human Baculovirus Insect Cells
PTPN12 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 41.8 kDa and the accession number is AAA36529.1.
TMPY-05308 CD45 Protein, Human, Recombinant (aa 1-529, His)

GP180,B220,L-CA,protein tyrosine phosphata...

Human HEK293 Cells
CD45 Protein, Human, Recombinant (aa 1-529, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is P08575-5.
TMPY-05748 CD45 Protein, Human, Recombinant (aa 26-577, His)

L-CA,T200,LCA,B220,protein tyrosine phosph...

Human HEK293 Cells
CD45 Protein, Human, Recombinant (aa 26-577, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.2 kDa and the accession number is P08575-3.
TMPJ-01017 Dtk Protein, Mouse, Recombinant (hFc)

tyro3,Tyrosine-protein kinase receptor TYR...

Mouse HEK293 Cells
Dtk Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is P55144.
TMPJ-01081 Dtk Protein, Human, Recombinant (His)

RSE,SKY,DTK,Tyrosine-protein kinase DTK,

Human HEK293 Cells
Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse homologues of chicken cEyk)constitute a new receptor tyrosine kinase subfamily. The extracellular domain of these proteins contain two Ig-like motifs and two fibronectin type III motifs. This characteristic topology is also found in neural cell adhesion molecules and in receptor tyrosine phosphatases. All three receptors bind the vitamin K-dependent protein growth-arrest specific gene 6 (Gas6) which is structurally related to th...
TMPJ-01018 Dtk Protein, Mouse, Recombinant (mFc)

TK19-2,Tyrosine-protein kinase RSE,Etk2/ty...

Mouse HEK293 Cells
Dtk Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 60-90 KDa and the accession number is P55144.
TMPY-04377 Brk Protein, Human, Recombinant (GST)

BRK,protein tyrosine kinase 6

Human Baculovirus Insect Cells
Brk Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 78 kDa and the accession number is Q13882-1.
TMPJ-00465 PTP1C Protein, Human, Recombinant (His)

HCP,Hematopoietic Cell Protein-Tyrosine Ph...

Human E. coli
Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1C is highly expressed in leukocyte cell type. It contains two SH2 domains and one tyrosine-protein phosphatase domain. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against inter...
TMPH-02278 PTPN5 Protein, Human, Recombinant (His & SUMO)

PTPN5,Neural-specific protein-tyrosine pho...

Human E. coli
May regulate the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors. PTPN5 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 45.5 kDa and the accession number is P54829.
TMPH-02277 PTPN11 Protein, Human, Recombinant (T253M & Q257L, His)

Protein-tyrosine phosphatase 1D,Tyrosi...

Human E. coli
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway. Dephosphorylates GAB1, ARHGAP35 and EGFR. Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulation of its RhoA binding activity. Dephosphorylates CDC73. Dephosphorylates SOX9 on tyrosine residues, leading to inactivate SOX9 and promote ossification.
TMPH-02011 PTPRB Protein, Human, Recombinant (His & SUMO)

PTPRB,Receptor-type tyrosine-protein phosp...

Human E. coli
PTPRB Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-02010 PTPRB Protein, Human, Recombinant (His)

Vascular endothelial protein tyrosine phos...

Human P. pastoris (Yeast)
PTPRB Protein, Human, Recombinant (His) is expressed in Yeast.
TMPH-02790 MUSK Protein, Mouse, Recombinant (His & Myc & SUMO)

Muscle-specific tyrosine-protein kinase re...

Mouse E. coli
MUSK Protein, Mouse, Recombinant (His & Myc & SUMO) is expressed in E. coli.
TMPJ-00449 AXL Protein, Human, Recombinant (hFc)

UFO,Tyrosine-protein kinase receptor UFO,A...

Human HEK293 Cells
AXL Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-115 KDa and the accession number is AAA61243.
TMPH-01718 MUSK Protein, Human, Recombinant (His)

Muscle, skeletal receptor tyrosine-protein...

Human P. pastoris (Yeast)
MUSK Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 53.8 kDa and the accession number is O15146.
TMPJ-00399 AXL Protein, Mouse, Recombinant (hFc)

Tyrosine-protein kinase receptor UFO,UFO,A...

Mouse HEK293 Cells
AXL Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is Q00993.
TMPY-04440 Brk Protein, Mouse, Recombinant (His & GST)

BRK,Tksk,protein tyrosine kinase 6,tks,Sik

Mouse Baculovirus Insect Cells
Brk Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 79.8 kDa and the accession number is Q64434.
TMPH-03719 YopH Protein, Yersinia enterocolitica, Recombinant (His & Myc)

yopH,Virulence protein,Tyrosine-protei...

Yersinia enterocolitica E. coli
Essential virulence determinant. This protein is a protein tyrosine phosphatase. The essential function of YopH in Yersinia pathogenesis is host-protein dephosphorylation. It contributes to the ability of the bacteria to resist phagocytosis by peritoneal macrophages.
TMPJ-01143 MERTK/Mer Protein, Human, Recombinant (aa 1-323, His)

MER,Receptor tyrosine kinase MerTK,Tyrosine

Human HEK293 Cells
Tyrosine-protein kinase Mer (MERTK) is a single-pass type I membrane protein which belongs to the MER/AXL/TYRO3 receptor kinase family. MERTK include two fibronectin type-III domains, two Ig-like C2-type domains, and one tyrosine kinase domain. It can’t be expressed in normal B- and T-lymphocytes, but it is usually expressed in numerous neoplastic B- and T-cell lines. MERTK could regulate many physiological processes, such as cell survival, migration, differentiation. It was demonstrated that t...
TMPH-02275 Lck Protein, Human, Recombinant (His)

Proto-oncogene Lck,T cell-specific protein-tyro...

Human E. coli
Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen-bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules...
TMPH-02987 PTPRS Protein, Mus musculus, Recombinant (His & Myc)

Ptprs,Receptor-type tyrosine-protein phosp...

Mouse Baculovirus Insect Cells
PTPRS Protein, Mus musculus, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 35.8 kDa and the accession number is B0V2N1.
TMPH-02013 PTPRZ1 Protein, Human, Recombinant (His)

Protein-tyrosine phosphatase receptor type...

Human P. pastoris (Yeast)
Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades. PTPRZ1 Protein, Human, Recombinant (His) is exp...
TMPJ-01085 DPT Protein, Human, Recombinant (hFc & His)

TRAMP and DPT,Tyrosine-rich acidic matrix prote...

Human HEK293 Cells
Dermatopontin, also known as Tyrosine-rich acidic matrix protein, TRAMP and DPT, is a secreted protein which belongs to the dermatopontin family. DPT is expressed in various tissues, such as fibroblasts, heart, skeletal muscle, brain and pancreas. It seems to mediate adhesion by cell surface integrin binding. DPT may serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. DPT can enhance TGFB1 activity through interaction with decorin. ...
TMPJ-00053 PRL-2 Protein, Human, Recombinant (His)

HU-PP-1,Protein tyrosine phosphatase type ...

Human E. coli
PTP4A2, also known as PRL2 or PTPCAAX2, is short for Protein tyrosine phosphatase type IVA 2. This protein exists in cell membrane, cytoplasm,endosome and membrane. PTP4A2 is often farnesylated during post-translational modification. Farnesylation is required for membrane targeting and for interaction with RABGGTB. The unfarnesylated forms are redirected to the nucleus and cytosol. It can stimulate progression from G1 into S phase during mitosis and promotes tumors. It also inhibits geranylgeran...
TMPH-02878 PTPRS Protein, Mouse, Recombinant (His & Myc)

Receptor-type tyrosine-protein phosphatase...

Mouse E. coli
Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycans. Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects on PTPRS oligomerization and regulation of neurite outgrowth. Contributes to the inhibition of neurite and axonal outgrowth by chondroitin sulfate proteoglycans, also after nerve transection. Plays a role in stimulating neurite outgrowth in response to the heparan sulfate proteo...
TMPH-02012 PTPRZ1 Protein, Human, Recombinant (E. coli, His)

Protein-tyrosine phosphatase receptor type...

Human E. coli
PTPRZ1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli.
TMPJ-01369 DPT Protein, Mouse, Recombinant (hFc)

EQ-1,Early quiescence protein 1,TRAMP,Tyrosine<...

Mouse HEK293 Cells
Dermatopontin is a widely expressed noncollagenous protein component of the extracellular matrix. It is a 22 kDa molecule that is tyrosine sulfated but not glycosylated. Dermatopontin is down regulated in fibrotic growths such as leiomyoma and scar tissue, inhibits cell proliferation, accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation, Dermatopontin deficient mice exhibit altered collagen matrix deposition and organization. Dermatopontin s...
TMPJ-00307 BLK Protein, Human, Recombinant (His)

Tyrosine-Protein Kinase Blk,BLK,B Lymphocy...

Human E. coli
Tyrosine-Protein Kinase Blk (BLK) contains one protein kinase domain, one SH2 domain and one SH3 domain. BLK is a non-receptor tyrosine kinase, which is involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulines and supports the pro-B to pre-B t...
TMPY-02584 14-3-3 beta Protein, Cynomolgus, Recombinant

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase...

Cynomolgus E. coli
14-3-3 beta Protein, Cynomolgus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 27.8 kDa and the accession number is Q4R572-2.
TMPH-01777 TYK2 Protein, Human, Recombinant (E. coli, His)

TYK2,Non-receptor tyrosine-protein kinase ...

Human E. coli
TYK2 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 37.9 kDa and the accession number is P29597.
TMPH-01778 TYK2 Protein, Human, Recombinant (His)

Non-receptor tyrosine-protein kinase TYK2,...

Human Baculovirus Insect Cells
TYK2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with N-10xHis tag. The predicted molecular weight is 34.4 kDa and the accession number is P29597.
TMPJ-00808 CD45RA Protein, Human, Recombinant (His)

PTPRC,CD45R,CD45,LCA,protein tyrosine phos...

Human HEK293 Cells
CD45RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-135 KDa and the accession number is P08575-8.
TMPJ-00794 CD45 Protein, Mouse, Recombinant (His)

CD45,receptor-type tyrosine-protein phosph...

Mouse HEK293 Cells
CD45 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 120-160 KDa and the accession number is P06800.
TMPH-02961 JAK1 Protein, Mouse, Recombinant (His)

Janus kinase 1,Jak1,Tyrosine-protein kinas...

Mouse E. coli
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Directly phosphorylates STAT but also activates STAT signaling through the transactivation of other JAK kinases associated with signaling receptors. JAK1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 39.1 kDa and the accession numb...
TMPH-01938 PRKCD Protein, Human, Recombinant (His)

Tyrosine-protein kinase PRKCD,PRKCD,Pr...

Human E. coli
PRKCD Protein, Human, Recombinant (His) is expressed in E. coli.
TMPJ-00410 CD45R0 Protein, Human, Recombinant (His)

CD45 antigen,L-CA,protein tyrosine phospha...

Human HEK293 Cells
CD45R0 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 80-120 KDa and the accession number is P08575-4.
TMPY-00487 PTPN9 Protein, Human, Recombinant (His & GST)

PTPMEG2,protein tyrosine phosphatase, non-...

Human Baculovirus Insect Cells
Protein tyrosine phosphatase non-receptor type 9 (PTPN9), also named PTP-MEG2, is an important member of the protein tyrosine phosphatase family that is involved in variety of human diseases.PTPN9 plays an important role in erythropoiesis by disrupting an inhibitory complex of phosphorylated STAT3, GATA1 and ZBP-89, providing new cellular and molecular insights into the role of ptpn9a in developmental hematopoiesis.
TMPY-02378 14‑3‑3 theta/YWHAQ Protein, Human, Recombinant (GST)

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase...

Human E. coli
The recently identified 14-3-3 tau, whose corresponding gene name is YWHAQ, is in a hypoxia-treated human trophoblast cell line. YWHAQ may play a role in epigenetic regulation of placental genes in the onset of Preeclampsia (PE). Moreover, there was a closer relationship between blood pressure and methylation levels of the YWHAQ promoter.
TMPH-02274 JAK2 Protein, Human, Recombinant (His)

JAK2,Janus kinase 2,Tyrosine-protein kinas...

Human E. coli
Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN-beta, IFN-gamma and multiple int...
TMPH-02273 JAK1 Protein, Human, Recombinant (His)

JAK1,Janus kinase 1,Tyrosine-protein kinas...

Human P. pastoris (Yeast)
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Directly phosphorylates STAT but also activates STAT signaling through the transactivation of other JAK kinases associated with signaling receptors.
TMPH-02272 JAK1 Protein, Human, Recombinant (E. coli, His)

Tyrosine-protein kinase JAK1,JAK1,Janus ki...

Human E. coli
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Directly phosphorylates STAT but also activates STAT signaling through the transactivation of other JAK kinases associated with signaling receptors.
TMPY-02369 TCPTP Protein, Mouse, Recombinant (aa 2-314, His)

protein tyrosine phosphatase, non-receptor...

Mouse Baculovirus Insect Cells
TCPTP Protein, Mouse, Recombinant (aa 2-314, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 38.7 kDa and the accession number is Q06180-1.
TMPJ-00405 EphA4 Protein, Human, Recombinant (hFc)

Ephrin type-A receptor 4,SEK,hEK8,TYRO1,Tyrosine-

Human HEK293 Cells
EphA4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is P54764.
TMPY-02179 14-3-3 epsilon Protein, Mouse, Recombinant (GST)

AU019196,tyrosine 3-monooxygenase/tryptophan 5-mono...

Mouse E. coli
14-3-3 epsilon Protein, Mouse, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 56.1 kDa and the accession number is P62259.
TMPJ-00404 EphA4 Protein, Human, Recombinant

Ephrin type-A receptor 4,TYRO1,HEK8,EK8,EPH-like kinase 8,SE...

Human HEK293 Cells
EphA4 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 60-80 KDa and the accession number is P54764.
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重组蛋白

VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00412
Species: Human
Expression System: HEK293 Cells
BTK Protein, Human, Recombinant (His)
Cat.No: TMPH-02271
Species: Human
Expression System: Baculovirus Insect Cells
PTP1B Protein, Human, Recombinant (His)
Cat.No: TMPY-04125
Species: Human
Expression System: E. coli
HER2/ERBB2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00778
Species: Human
Expression System: HEK293 Cells
TCPTP Protein, Human, Recombinant
Cat.No: TMPY-03484
Species: Human
Expression System: Baculovirus Insect Cells
PTPN12 Protein, Human, Recombinant
Cat.No: TMPY-03548
Species: Human
Expression System: Baculovirus Insect Cells
CD45 Protein, Human, Recombinant (aa 1-529, His)
Cat.No: TMPY-05308
Species: Human
Expression System: HEK293 Cells
CD45 Protein, Human, Recombinant (aa 26-577, His)
Cat.No: TMPY-05748
Species: Human
Expression System: HEK293 Cells
Dtk Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-01017
Species: Mouse
Expression System: HEK293 Cells
Dtk Protein, Human, Recombinant (His)
Cat.No: TMPJ-01081
Species: Human
Expression System: HEK293 Cells
Dtk Protein, Mouse, Recombinant (mFc)
Cat.No: TMPJ-01018
Species: Mouse
Expression System: HEK293 Cells
Brk Protein, Human, Recombinant (GST)
Cat.No: TMPY-04377
Species: Human
Expression System: Baculovirus Insect Cells
PTP1C Protein, Human, Recombinant (His)
Cat.No: TMPJ-00465
Species: Human
Expression System: E. coli
PTPN5 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-02278
Species: Human
Expression System: E. coli
PTPN11 Protein, Human, Recombinant (T253M & Q257L, His)
Cat.No: TMPH-02277
Species: Human
Expression System: E. coli
PTPRB Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-02011
Species: Human
Expression System: E. coli
PTPRB Protein, Human, Recombinant (His)
Cat.No: TMPH-02010
Species: Human
Expression System: P. pastoris (Yeast)
MUSK Protein, Mouse, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-02790
Species: Mouse
Expression System: E. coli
AXL Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00449
Species: Human
Expression System: HEK293 Cells
MUSK Protein, Human, Recombinant (His)
Cat.No: TMPH-01718
Species: Human
Expression System: P. pastoris (Yeast)
AXL Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00399
Species: Mouse
Expression System: HEK293 Cells
Brk Protein, Mouse, Recombinant (His & GST)
Cat.No: TMPY-04440
Species: Mouse
Expression System: Baculovirus Insect Cells
YopH Protein, Yersinia enterocolitica, Recombinant (His & Myc)
Cat.No: TMPH-03719
Species: Yersinia enterocolitica
Expression System: E. coli
MERTK/Mer Protein, Human, Recombinant (aa 1-323, His)
Cat.No: TMPJ-01143
Species: Human
Expression System: HEK293 Cells
Lck Protein, Human, Recombinant (His)
Cat.No: TMPH-02275
Species: Human
Expression System: E. coli
PTPRS Protein, Mus musculus, Recombinant (His & Myc)
Cat.No: TMPH-02987
Species: Mouse
Expression System: Baculovirus Insect Cells
PTPRZ1 Protein, Human, Recombinant (His)
Cat.No: TMPH-02013
Species: Human
Expression System: P. pastoris (Yeast)
DPT Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-01085
Species: Human
Expression System: HEK293 Cells
PRL-2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00053
Species: Human
Expression System: E. coli
PTPRS Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02878
Species: Mouse
Expression System: E. coli
PTPRZ1 Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-02012
Species: Human
Expression System: E. coli
DPT Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-01369
Species: Mouse
Expression System: HEK293 Cells
BLK Protein, Human, Recombinant (His)
Cat.No: TMPJ-00307
Species: Human
Expression System: E. coli
14-3-3 beta Protein, Cynomolgus, Recombinant
Cat.No: TMPY-02584
Species: Cynomolgus
Expression System: E. coli
TYK2 Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-01777
Species: Human
Expression System: E. coli
TYK2 Protein, Human, Recombinant (His)
Cat.No: TMPH-01778
Species: Human
Expression System: Baculovirus Insect Cells
CD45RA Protein, Human, Recombinant (His)
Cat.No: TMPJ-00808
Species: Human
Expression System: HEK293 Cells
CD45 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00794
Species: Mouse
Expression System: HEK293 Cells
JAK1 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02961
Species: Mouse
Expression System: E. coli
PRKCD Protein, Human, Recombinant (His)
Cat.No: TMPH-01938
Species: Human
Expression System: E. coli
CD45R0 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00410
Species: Human
Expression System: HEK293 Cells
PTPN9 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-00487
Species: Human
Expression System: Baculovirus Insect Cells
14‑3‑3 theta/YWHAQ Protein, Human, Recombinant (GST)
Cat.No: TMPY-02378
Species: Human
Expression System: E. coli
JAK2 Protein, Human, Recombinant (His)
Cat.No: TMPH-02274
Species: Human
Expression System: E. coli
JAK1 Protein, Human, Recombinant (His)
Cat.No: TMPH-02273
Species: Human
Expression System: P. pastoris (Yeast)
JAK1 Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-02272
Species: Human
Expression System: E. coli
TCPTP Protein, Mouse, Recombinant (aa 2-314, His)
Cat.No: TMPY-02369
Species: Mouse
Expression System: Baculovirus Insect Cells
EphA4 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00405
Species: Human
Expression System: HEK293 Cells
14-3-3 epsilon Protein, Mouse, Recombinant (GST)
Cat.No: TMPY-02179
Species: Mouse
Expression System: E. coli
EphA4 Protein, Human, Recombinant
Cat.No: TMPJ-00404
Species: Human
Expression System: HEK293 Cells
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Cat. No. Product Name Target Signaling Pathways
TMID-0096 P-CRESOL-d3 (METHYL-d3)

P-CRESOL-d3 (METHYL-d3) 是 P-CRESOL 的氘代化合物。P-CRESOL 的 CAS 号为 106-44-5。p-Cresol 是一种部分亲脂性部分,在正常条件下与血浆蛋白(接近 100%)强烈结合。对甲酚通过结合代谢,主要是硫酸化和葡萄糖醛酸化,但未结合的对甲酚至少部分通过尿液去除。

同位素标记化合物

P-CRESOL-d3 (METHYL-d3)
Cat.No: TMID-0096
Synonym:
Target:
TargetMol Loading
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