|
TMPJ-01387
|
PACSIN2 Protein, Human, Recombinant (His)
Protein Kinase C and Casein Kinase Substrate in Neurons<...
|
Human
|
HEK293 Cells
|
|
Protein Kinase C and Casein Kinase Substrate in Neurons Protein 2 (PACSIN2) is a member of the PACSIN family. PACSIN2 is localized to the plasma membrane via its coiled-coil domain. PACSIN2 is widely expressed and contains one FCH domain and one SH3 domain. PACSIN2 forms homo- and hetero-aggregates with other PACSINs. PACSIN2 may play a role in vesicle formation and transport. In addition, PACSIN2 is involved in linking the actin cytoskeleton with vesicle formation by regulating tubulin polymeri... |
|
TMPJ-01307
|
PACSIN1 Protein, Human, Recombinant (His)
Protein Kinase C and Casein Kinase Substrate in Neurons<...
|
Human
|
HEK293 Cells
|
|
Protein Kinase C and Casein Kinase Substrate in Neurons Protein 1 (PACSIN1) belongs to the PACSIN family. PACSIN1 contains one FCH domain and one SH3 domain. PACSIN1 is highly expressed in the brain and at lower leves in the heart, pancreas, and liver. PACSIN1 may play a role in vesicle formation and transport. PACSIN1 has been shown to interact with DNM1, PACSIN3, Huntingtin, and PACSIN2. In addition, PACSIN1 is phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC). |
|
TMPK-00810
|
tPA Protein, Mouse, Recombinant (His)
PLAT,Reteplase,t-PA,tPA,Alteplase
|
Mouse
|
HEK293 Cells
|
|
Tissue plasminogen activator (tPA) is the predominant plasminogen activator present in the vascular and nervous systems.t tPA is not only neuroprotective for postnatal primary cortical neurons, but also that the
predominant route for enhancing cell survival is via an mTORdependent mechanism. |
|
TMPY-03425
|
Tau Protein, Human, Recombinant (His)
PPND,FTDP-17,MTBT1,DDPAC,MAPTL,MTBT2,microtubule-associated ...
|
Human
|
E. coli
|
|
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP... |
|
TMPY-05510
|
BDNF Protein, Mouse, Recombinant (His)
brain-derived neurotrophic factor
|
Mouse
|
HEK293 Cells
|
|
BDNF is a member of thenerve growth factorfamily. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. It participates in axonal growth,... |
|
TMPK-00735
|
CXCL13/BCA-1 Protein, Mouse, Recombinant (His)
ANGIE,BLR1L,ANGIE2,BLC,SCYB13,BCA1,BCA-1
|
Mouse
|
HEK293 Cells
|
|
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice. CXCL13/BCA-1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The pred... |
|
TMPK-01207
|
DLL3 Protein, Human, Recombinant (His & Avi), Biotinylated
Pudgy,δ3,SCDO1δ3,Delta3,SCDO1delta3,SCDO1,DLL3
|
Human
|
HEK293 Cells
|
|
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight ... |
|
TMPJ-00135
|
BDNF Protein, Human/Murine/Rat, Recombinant
BDNF,Abrineurin,Brain-Derived Neurotrophic Factor
|
Human,Mouse,Rat
|
E. coli
|
|
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. ... |
|
TMPY-04069
|
Neurotrophin 3 Protein, Human, Recombinant
NGF2,HDNF,NT-3,neurotrophin 3,NGF-2,NT3
|
Human
|
E. coli
|
|
NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. NTF3 is a key mediator of neuronal development during the early neurogenic period. NTF3 is a novel target gene of POU3F2 and that the POU3F2/NTF3 pathway plays a role in the process of neuronal differentiation. ... |
|
TMPY-01085
|
VLDLR Protein, Human, Recombinant (His)
VLDLRCH,CAMRQ1,CHRMQ1,very low density lipoprotein receptor,...
|
Human
|
HEK293 Cells
|
|
The very low density lipoprotein receptor, known as VLDLR, is a single-pass type 1 integral membrance protein and a member of the LDL receptor family. This receptor family includes LDL receptor, LRP, megalin, VLDLR and ApoER2, and is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar sdomain. VLDLR contains 3 EGF-like domains, 8 LDL-receptor class A domains, as well as 6 LDL-receptor class B repeats, and is ... |
|
TMPJ-01065
|
Noggin/NOG Protein, Mouse, Recombinant (His)
Nog,Noggin
|
Mouse
|
HEK293 Cells
|
|
Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal peptide that is cleaved to generate the 213 aa residue mature protein which is secreted as a homodimeric glycoprotein. Secreted Noggin probably remains close to the cell surface due to its binding of heparin-containing proteoglycans. Noggin binds some BMPs such as BMP4 with high affi... |
|
TMPJ-00051
|
IL-3 Protein, Mouse, Recombinant (His)
Mast cell growth factor,Il3,Multipotential colony-stimulatin...
|
Mouse
|
HEK293 Cells
|
|
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. In addition, IL-3 also affects the functional activity of mature mast cells, basophils, eosinophils and macrophages.Because of its multiple functions and targets, it was originally studied under different names, including mast cell growth factor P-cell stimulating factor, bu... |
|
TMPY-02245
|
SNAP-25 Protein, Human, Recombinant (His)
synaptosomal-associated protein, 25kDa,SEC9,SNAP,RIC-4,dJ106...
|
Human
|
E. coli
|
|
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the sp... |
|
TMPY-00485
|
Olfactory Marker Protein Protein, Human, Recombinant (His)
OMP,olfactory marker protein
|
Human
|
E. coli
|
|
OMP (Olfactory Marker Protein) is a Protein Coding gene. OMP is a protein expressed in the mature olfactory and vomeronasal neurons of many vertebrates, such as mammals, amphibians, and bony fishes. Its structure and protein sequence are highly conserved between the mouse, rat, and human. OMP is a ubiquitous, cytoplasmic protein found in mature olfactory receptor neurons of all vertebrates. It participates in the olfactory signal transduction pathway. OMP expression is a hallmark of mature verte... |
|
TMPK-00592
|
Latexin Protein, Human, Recombinant (His)
ECI,TCI,LXN,MUM
|
Human
|
E. coli
|
|
Latexin, the endogenous protein inhibitor of the A/B subfamily of metallocarboxypeptidases, is expressed in small nociceptive neurons in sensory ganglia and in a subset of neurons in the telencephalon. Recently, the latexin (Lxn) gene was identified as a potential tumor suppressor in several types of solid tumors and lymphoma, and Lxn expression was found to be absent or downregulated in leukemic cells. |
|
TMPH-02187
|
Tenascin Protein, Human, Recombinant (E. coli, His)
GMEM,Glioma-associated-extracellular matrix antigen,Neuronec...
|
Human
|
E. coli
|
|
Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells. |
|
TMPK-00495
|
CADM3 Protein, Cynomolgus, Recombinant (His)
NECL1,IGSF4B,CADM3,TSLC1-like 1,GSF4B,NECL-1,TSLL1,SynCAM3,m...
|
Cynomolgus
|
HEK293 Cells
|
|
Cell adhesion molecules belonging to the Cadm family, and in particular Cadm3 (axonal) and its heterophilic binding partner Cadm4 (Schwann cell), mediate these interactions along the internode.over-expressing Cadm3 on the surface of DRG neuron axons results in an almost complete inability by Schwann cells to form myelin segments. Axons of superior cervical ganglion (SCG) neurons, which do not normally support the formation of myelin segments by Schwann cells, express higher levels of Cadm3 compa... |
|
TMPH-01769
|
Neurotrophin 3 Protein, Human, Recombinant (His)
NTF3,HDNF,Neurotrophic factor,Neurotrophin-3,Nerve growth fa...
|
Human
|
E. coli
|
|
Seems to promote the survival of visceral and proprioceptive sensory neurons. Neurotrophin 3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.7 kDa and the accession number is P20783. |
|
TMPK-01088
|
PODXL2 Protein, Mouse, Recombinant (His)
UNQ1861/PRO3742,oct-8,PODLX2,OTF8,Endoglycan,BRN1,EG,brain-1
|
Mouse
|
HEK293 Cells
|
|
Transmembrane protein endoglycan (PODXL2), which belongs to the CD34-family of highly glycosylated sialomucins. Endoglycan is broadly expressed in the developing mouse brains and is proteolytically shed in vitro in mouse neurons and in vivo in mouse brains. Endoglycan shedding in primary neurons was mediated by the transmembrane protease a disintegrin and metalloprotease 10 (ADAM10), but not by its homolog ADAM17. PODXL2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells wi... |
|
TMPH-01797
|
NR4A2 Protein, Human, Recombinant (His)
NR4A2,Immediate-early response protein NOT,Nuclear receptor ...
|
Human
|
P. pastoris (Yeast)
|
|
Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons. NR4A2 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 68.6 kDa and the accession number is P43354. |
|
TMPH-02555
|
C1QL1 Protein, Mouse, Recombinant (His)
C1q and tumor necrosis factor-related protein 14,Complement ...
|
Mouse
|
P. pastoris (Yeast)
|
|
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. |
|
TMPH-02118
|
SCN1A Protein, Human, Recombinant (His)
Sodium channel protein brain I subunit alpha,Sodium channel ...
|
Human
|
E. coli
|
|
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. Plays a key role in brain, probably by regulating the moment when neurotransmitters are released in neurons. Involved in sensory perception of mechanical pain: activation in somatosensory neur... |
|
TMPJ-00692
|
GAS7 Protein, Human, Recombinant (His)
GAS-7,GAS7,Growth Arrest-Specific Protein 7,KIAA0394
|
Human
|
E. coli
|
|
Growth Arrest-Specific Protein 7 (GAS7) is expressed primarily in terminalaly differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 may play a role in neuronal development by promoting maturation and morphological differentiation of cerebellar neurons. Inhibition of GAS7 production in terminally differentiating cultures of embryonic murine cerebullum impedes neurite outgrowth. The hyper-expression of GAS7 may play an major role in the initiation and development... |
|
TMPH-02214
|
Tomoregulin-1 Protein, Human, Recombinant (His)
TMEFF2,Tomoregulin-2,Transmembrane protein with EGF-like and...
|
Human
|
HEK293 Cells
|
|
May be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation. |
|
TMPH-01381
|
GDNF Protein, Human, Recombinant (His & SUMO)
Astrocyte-derived trophic factor,GDNF,Glial cell line-derive...
|
Human
|
E. coli
|
|
Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. GDNF Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 31.1 kDa and the accession number is P39905. |
|
TMPH-03341
|
Neurotrophin 3 Protein, Rat, Recombinant (His & Myc)
Neurotrophin-3,Neurotrophic factor,Nerve growth factor 2,HDN...
|
Rat
|
E. coli
|
|
Seems to promote the survival of visceral and proprioceptive sensory neurons. Neurotrophin 3 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 21.1 kDa and the accession number is P18280. |
|
TMPH-01675
|
Meteorin Protein, Human, Recombinant (His)
Meteorin,METRN
|
Human
|
E. coli
|
|
Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia. |
|
TMPH-03146
|
LAMP5 Protein, Pongo abelii, Recombinant (His & Myc)
Lysosome-associated membrane glycoprotein 5,LAMP5,Brain and ...
|
Pongo abelii
|
E. coli
|
|
Plays a role in short-term synaptic plasticity in a subset of GABAergic neurons in the brain. LAMP5 Protein, Pongo abelii, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 30.4 kDa and the accession number is Q5R5V2. |
|
TMPK-01213
|
PODXL2 Protein, Human, Recombinant (His)
BRN1,oct-8,UNQ1861/PRO3742,brain-1,EG,Endoglycan,PODLX2,OTF8
|
Human
|
HEK293 Cells
|
|
Transmembrane protein endoglycan (PODXL2), which belongs to the CD34-family of highly glycosylated sialomucins. Endoglycan is broadly expressed in the developing mouse brains and is proteolytically shed in vitro in mouse neurons and in vivo in mouse brains. Endoglycan shedding in primary neurons was mediated by the transmembrane protease a disintegrin and metalloprotease 10 (ADAM10), but not by its homolog ADAM17. PODXL2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells wi... |
|
TMPK-01113
|
IL-31RA Protein, Human, Recombinant (aa 20-519, hFc)
PRO21384,GLM-RMGC125346,GLM-R,IL-31R-alpha,IL-31RA,ZcytoR17,...
|
Human
|
HEK293 Cells
|
|
Interleukin-31 receptor A (IL-31RA) is a newly identified type I cytokine receptor, that is related to gp130, the common receptor of the interleukin (IL) -6 family cytokines. IL-31RA forms a functional receptor complex for IL-31 together with the beta subunit of oncostatin M receptor (OSMRbeta). OSMRbeta is expressed in a subset of small-sized nociceptive neurons of adult dorsal root ganglia (DRGs).IL-31 and OSM may thus have redundant functions in the development of OSMRbeta-expressing neurons.... |
|
TMPY-00286
|
Neuropeptide Y Protein, Human, Recombinant (hFc)
PYY4,neuropeptide Y
|
Human
|
HEK293 Cells
|
|
NPY (Neuropeptide Y) is a Protein Coding gene. This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. NPY is a neuromodulator that is widely expressed throughout the central nervous system (CNS) and is consecrated with classic neurotransmitters including GABA and glutamate. NPY/Agouti-related protein (AgRP) ne... |
|
TMPH-01669
|
Metallothionein-3/MT3 Protein, Human, Recombinant (His & SUMO)
Metallothionein-III,Metallothionein-3,GIFB,MT3,Growth inhibi...
|
Human
|
E. coli
|
|
Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro. |
|
TMPK-01096
|
IL-31RA Protein, Mouse, Recombinant (His)
GPL,CRL3Glmr,IL-31RA,GLM-R,ZcytoR17,CRL3,PRO21384,GLM-RMGC12...
|
Mouse
|
HEK293 Cells
|
|
Interleukin-31 receptor A (IL-31RA) is a newly identified type I cytokine receptor, that is related to gp130, the common receptor of the interleukin (IL) -6 family cytokines. IL-31RA forms a functional receptor complex for IL-31 together with the beta subunit of oncostatin M receptor (OSMRbeta). OSMRbeta is expressed in a subset of small-sized nociceptive neurons of adult dorsal root ganglia (DRGs).IL-31 and OSM may thus have redundant functions in the development of OSMRbeta-expressing neurons.... |
|
TMPJ-00998
|
MECP2 Protein, Human, Recombinant (His)
Methyl-CpG-binding protein 2,MeCp-2 protein,MECP2
|
Human
|
HEK293 Cells
|
|
The MeCP2 helps regulate gene activity (expression) by modifying chromatin, the complex of DNA and protein that packages DNA into chromosomes. The MeCP2 protein is present in cells throughout the body, although it is particularly abundant in brain cells.In the brain, the MeCP2 protein likely plays a role in maintaining connections (synapses) between neurons, where cell-to-cell communication occurs. The alternative splicing of proteins is critical for normal communication between neurons and may ... |
|
TMPH-03247
|
Artemin Protein, Rat, Recombinant (His & Myc)
Artemin,Artn
|
Rat
|
E. coli
|
|
Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue. Artemin Protein, Rat, Recombinant (His & Myc) is expressed in E. coli ... |
|
TMPY-01620
|
MDGA2 Protein, Mouse, Recombinant (His)
6720489L24Rik,Adp,MAM domain containing glycosylphosphatidyl...
|
Mouse
|
HEK293 Cells
|
|
MAM domain-containing glycosylphosphatidylinositol anchor protein 2, also known as MAM domain-containing protein 1, MDGA2, and MAMDC1, is a cell membrane protein that contains six Ig-like (immunoglobulin-like) domains and one MAM domain. Analyses of the full-length coding region of MDGA1 and MDGA2 indicate that they encode proteins that comprise a novel subgroup of the Ig superfamily and have a unique structural organization consisting of six immunoglobulin (Ig)-like domains followed by a single... |
|
TMPK-01114
|
IL-31RA Protein, Human, Recombinant (aa 20-519, His)
GLM-RMGC125346,CRL3,GLM-R,PRO21384,Gp130-like receptor,CRL3G...
|
Human
|
HEK293 Cells
|
|
Interleukin-31 receptor A (IL-31RA) is a newly identified type I cytokine receptor, that is related to gp130, the common receptor of the interleukin (IL) -6 family cytokines. IL-31RA forms a functional receptor complex for IL-31 together with the beta subunit of oncostatin M receptor (OSMRbeta). OSMRbeta is expressed in a subset of small-sized nociceptive neurons of adult dorsal root ganglia (DRGs).IL-31 and OSM may thus have redundant functions in the development of OSMRbeta-expressing neurons.... |
|
TMPK-00352
|
Siglec-4a/MAG Protein, Human, Recombinant (His & Avi), Biotinylated
S-MAG,MAG,GMA,Siglec-4a,Siglec4a
|
Human
|
HEK293 Cells
|
|
Siglec-4a, also known as Myelin-Associated Glycoprotein (MAG), is a type I transmembrane glycoprotein belonging to the Siglec family, a subgroup of the Ig superfamily. Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2 (By similarity). |
|
TMPJ-00305
|
SIRP alpha Protein, Cynomolgus, Recombinant (aa 31-369, His)
Inhibitory Feceptor SHPS-1,MyD-1 Antig,Brain Ig-Like Molecul...
|
Cynomolgus
|
HEK293 Cells
|
|
Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can express in various tissues, mainly on brain and myeloid cells, including macrophages, neutrophils, dendritic and Langerhans cells. It also can detect in neurons, smooth muscle and endothelial cells. SIRPA is an immunoglobulin-like cell surface receptor for CD47. SIRPα acts as docking ... |
|
TMPJ-00306
|
SIRP alpha Protein, Human, Recombinant (His & Avi), Biotinylated
Brain Ig-Like Molecule with Tyrosine-Based Activation Motifs...
|
Human
|
HEK293 Cells
|
|
Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can express in various tissues, mainly on brain and myeloid cells, including macrophages, neutrophils, dendritic and Langerhans cells. It also can detect in neurons, smooth muscle and endothelial cells. SIRPA is an immunoglobulin-like cell surface receptor for CD47. SIRPα acts as docking ... |
|
TMPH-02585
|
ACOD1 Protein, Mouse, Recombinant (His & Myc)
Cis-aconitate decarboxylase,Cis-aconitic acid decarboxylase,...
|
Mouse
|
Baculovirus Insect Cells
|
|
Cis-aconitate decarboxylase that catalyzes production of itaconate and is involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the anti... |
|
TMPH-03292
|
FGF-20 Protein, Rat, Recombinant (His & Myc)
Fibroblast growth factor 20,Fgf20
|
Rat
|
E. coli
|
|
Neurotrophic factor that regulates central nervous development and function. May play an important role in dopaminergic neurons in the substantia nigra. FGF-20 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 31.0 kDa and the accession number is Q9EST9. |
|
TMPJ-01182
|
SIRP alpha Protein, Mouse, Recombinant (MIgG2a)
SIRP,CD172 Antigen-Like Family Member A,SIRPA,MFR,Signal-Reg...
|
Mouse
|
HEK293 Cells
|
|
SIRPα is a type I transmembrane glycoprotein.It contains two Ig-like C1-type domains and one Ig-like V-type domain. Mouse SIRP alpha ECD shares 61%, 75%, 62%, 61%, and 59% aa sequence identity with human, rat, equine, bovine, and porcine SIRP alpha, respectively.SIRPα can express in various tissues, mainly on brain and myeloid cells, including macrophages, neutrophils, dendritic and Langerhans cells. It also can detect in neurons, smooth muscle and endothelial cells. SIRPA is an immunoglobulin-l... |
|
TMPH-03375
|
Stathmin-2 Protein, Rat, Recombinant (His)
Superior cervical ganglion-10 protein,Stmn2,Stathmin-2
|
Rat
|
E. coli
|
|
Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone. Stathmin-2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26.7 kDa and the accession number is P21818. |
|
TMPH-02858
|
Wnt2 Protein, Mouse, Recombinant (His)
Protein Wnt-2,INT-1-related protein,Wnt2
|
Mouse
|
E. coli
|
|
Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons. |
|
TMPH-02600
|
C1QL3 Protein, Mouse, Recombinant (His & Myc)
C1ql,Gliacolin,C1q and tumor necrosis factor-related protein...
|
Mouse
|
Baculovirus Insect Cells
|
|
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Plays a role in glucose homeostasis. Via AMPK signaling pathway, stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, reduces the expression of gluconeogenic enzymes G6PC1 and PCK1 and hence decreases de novo glucose production. |
|
TMPY-02579
|
NRN1 Protein, Human, Recombinant (His)
NRN,dJ380B8.2,MGC44811,neuritin 1
|
Human
|
Baculovirus Insect Cells
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Neuritin 1 (NRN1) is a member of the neuritin family. Neuritin is a glycosylphosphatidylinositol-anchored protein induced by neural activity. It is expressed in postmitotic-differentiating neurons of the developing nervous system and a population of small-diameter neurons in the dorsal root ganglia and was anterogradely and retrogradely transported. Neuritin message is induced by neuronal activity and by the activity-regulated neurotrophins BDNF, nerve growth factor (NGF), and NT-3. Purified rec... |
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TMPY-02810
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Ninjurin-1 Protein, Rat, Recombinant (hFc)
ninjurin 1
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Rat
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HEK293 Cells
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Ninjurin-1, also known as NINJ1, is a member of the Ninjurin family of transmembrane (TM) proteins. It is expressed in CD19(+) CD10(+) B-cell progenitor cells and higher levels in B-lineage acute lymphoblastic leukemia cells. Ninjurin-1 is expressed also in some other adult and embryonic tissues, predominantly in epithelial cells. Its expression is upregulated after axotomy in neurons and Schwann cells surrounding the distal nerve segment. Upregulated expression of ninjurin-1 has been identified... |
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TMPH-01256
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Dystonin Protein, Human, Recombinant (His & SUMO)
DT,DST,BPAG1,BP240,BP230,KIAA0728,Dystonin,DMH
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Human
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E. coli
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Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transpo... |
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TMPH-01257
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Dystonin Protein, Human, Recombinant (His)
DT,BP230,Dystonin,BP240,DST,DMH,BPAG1,KIAA0728
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Human
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P. pastoris (Yeast)
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Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transpo... |
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