251
43
3
1
189
6
Cat. No. | Product Name | ||
---|---|---|---|
LF9000 | 半胱氨酸靶向共价抑制剂库 | 3400 compounds | |
It contains over 3,400 potential covalent modifiers. | |||
L9411 | 半胱氨酸共价化合物库 | 70 compounds | |
半胱氨酸共价库包含 70 个化合物。 | |||
L7600 | 趋化因子抑制剂库 | 59 compounds | |
59 种趋化因子或其受体抑制剂的独特集合,可用于高通量筛选和高内涵筛选; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
C0001 |
Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO)
蛋白酶抑制剂 Cocktail (EDTA-Free, 100× in DMSO) |
Solution (EDTA-Free,100× in DMSO) | Serine proteases, Aminopeptidases, <em>Cysteine</em> proteases, Aspartic proteases |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1547 |
L-Cysteine methyl ester hydrochloride
L-半胱氨酸甲酯盐酸盐,L-Cysteine methyl ester hydrochloride(Acdrile) |
Amino Acids and Derivatives | Metabolism |
L-Cysteine methyl ester hydrochloride (L-Cysteine methyl ester hydrochloride (Acdrile)) 是一种粘痰溶解剂,是镇咳药,可用于缓解大量粘痰引起的呼吸困难。 | |||
T8483 |
Cysteine thiol probe
Methyl (4-bromobenzoyl)-L-cysteinate |
Others | Others |
Cysteine thiol probe (Methyl (4-bromobenzoyl)-L-cysteinate) 是基于硫醇的探针,旨在标记亲电子的天然产物。它能够结合基于烯酮,β-内酰胺和 β-内酯的亲电子代谢物。它具有理想药效团探针的每个特征,并具有发色团。 | |||
T38155 |
N-Acetyl-D-cysteine
|
Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB |
N-Acetyl-D-cysteine 具有抗氧化活性,机制是通过与巯基反应清除ROS。N-Acetyl-D-cysteine 不能进入谷胱甘肽代谢途径。 | |||
T36816 |
S-trityl-L-Cysteine
STLC |
Kinesin | Cytoskeletal Signaling |
S-Trityl-L-cysteine 是别构驱动蛋白Eg5的选择性抑制剂。rityl-L-cysteine 抑制基础 ATPase 活性的IC50为 1 μM,抑制微管激活的 ATPase 活性的IC50为 140 nM。S-Trityl-L-cysteine 显示出抗肿瘤活性。 | |||
T23303 |
S-Sulfo-L-cysteine sodium salt
|
Antioxidant; GluR | Neuroscience; oxidation-reduction |
S-Sulfo-L-cysteine sodium salt 在高浓度下对 mGluR1α 和 mGluR5a 显示出较弱的亲和力且具有潜在的抗氧化活性。 | |||
T1547L |
Cysteine monohydrate
Cysteine hydrate,L-Cysteine, monohydrate |
Others | Others |
Cysteine monohydrate is a semi-essential proteinogenic amino acid. | |||
T31156 |
Cysteine hydrazide
Cysteine,L-hydrazide |
Others | Others |
Cysteine hydrazide is an enrichment tool for the mass spectrometric characterization of bacterial-free oligosaccharides. | |||
T34954 |
Tripalmitoyl cysteine
Tripalmitoyl-S-glyceryl cysteine |
Others | Others |
Tripalmitoyl cysteine is a synthetic analog of the N-terminal lipid part of bacterial lipoprotein. | |||
T34853 |
Thiola-cysteine disulfide
Mercaptopropionylglycine-cysteine disulfide |
Others | Others |
Thiola-cysteine disulfide is a urinary metabolite of thiola. | |||
T31157 |
Cysteine isopropyl ester
Cysteine isopropylester,CIPE |
Others | Others |
Cysteine isopropyl ester is a chemoprotectant against paracetamol-induced toxicity. | |||
T64327 |
Fmoc-Cys(Acm)-OH
Fmoc-S-acetamidomethyl-L-cysteine |
Amino Acids and Derivatives | Metabolism |
Fmoc-Cys(Acm)-OH (Fmoc-S-acetamidomethyl-L-cysteine) 是一种半胱氨酸衍生物。 | |||
T10363 |
Arazine
N-Acetyl-S-farnesyl-L-cysteine |
Others | Others |
Arazine (N-Acetyl-S-farnesyl-L-cysteine) 可以成为异戊二烯基半胱氨酸甲基转移酶的底物通过与异戊二烯化 G 蛋白或其受体位点竞争。 Arazine 是 G 蛋白和 GPCR 信号传导的细胞渗透性调节剂。 | |||
T24018 |
D-Ribose-L-cysteine
DRiboseLcysteine,Ribcys,Riboceine,J424.013H,D Ribose L cysteine |
Others | Others |
D-Ribose-L-cysteine is the antioxidant glutathione precursor. | |||
T83898 |
S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine
SFN-Cys,D,L-Sulforaphane-L-cysteine |
Others | Others |
S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine (SFN-Cys) 是一种异硫氰酸酯衍生物及第一类和第二类组蛋白去乙酰化酶(HDAC)抑制剂和抗癌剂硫代硫酸烯醇醚的活性代谢产物。它通过巯基乙酸途径酶从硫代硫酸烯醇醚经DL-硫代硫酸烯醇醚谷胱甘肽和硫代硫酸烯醇醚半胱氨酸甘肽中间体形成。SFN-Cys (20 µM) 通过创伤愈合和腔室分析实验,分别减少了U87MG和U373 MG胶质母细胞瘤细胞的侵袭和迁移。在45 µM的浓度下,它降低了对紫杉醇耐药的A549肺癌细胞(A549/T)中的α-微管蛋白、βIII-微管蛋白、司他敏1和X连锁抑制剂的凋亡(XIAP)的水平,并减少了细胞密度。使用30 µM浓度的SFN-Cys诱导U87MG和U373 MG细胞凋亡和G2/M期细胞周期停滞。 | |||
T10925L |
Cysteine Protease inhibitor hydrochloride
Cysteine Protease inhibitor hydrochloride (921625-62-9 free base) |
Others | Others |
Cysteine Protease inhibitor hydrochloride 是一种半胱氨酸蛋白酶(cysteine protease)抑制剂。 | |||
T15047 |
Dacisteine
N,S-Diacetyl-L-cysteine,达西司坦 |
Others | Others |
Dacisteine (N,S-Diacetyl-L-cysteine) 是 New Delhi metallo-beta-lactamase-1 (NDM-1) 的抑制剂 (IC50 = 1000 μM)。 | |||
T34689 |
S-Palmitoyl cysteine
|
Others | Others |
S-Palmitoyl cysteine is an important dynamic post-translational modification of cysteine residues within proteins. | |||
T31158 |
Cysteine thiosulfonate
Alanine sulfodisulfane |
Others | Others |
Cysteine thiosulfonate plays a role in cystine metabolism. | |||
T38312 |
L-Cysteine-glutathione disulfide
|
Others | Others |
L-Cysteine-glutathione disulfide, a glutathione derivative endogenous to mammalian cells, is comprised of the oxidized form of free glutathione tripeptide linked via a disulfide bond to L-cysteine. It has been shown to protect mice against acetaminophen-induced hepatotoxicity. | |||
T3612 |
Carbocisteine
Carbocysteine,羧甲司坦,Broncodeterge,Mucodyne,S-Carboxymethyl-L-cysteine |
Others | Others |
Carbocisteine (Mucodyne) 常被用作具有粘液溶解和祛痰作用的抗感染鼻喷雾剂。 | |||
T10925 | Cysteine Protease inhibitor | Others | Others |
Cysteine protease inhibitors are inhibitors of cysteine proteases. Target: Cysteine Protease | |||
T65347 |
Methyl acetyl-L-cysteinate
(R)-Methyl 2-acetamido-3-mercaptopropanoate,N-Acetyl-L-cysteine methyl ester |
Amino Acids and Derivatives | Metabolism |
Methyl acetyl-L-cysteinate (N-Acetyl-L-cysteine methyl ester) 是一种半胱氨酸衍生物,可用于生物合成且与机体代谢和免疫有关。 | |||
T10924 |
Cysteine protease inhibitor-2
|
Cysteine Protease | Proteases/Proteasome |
Cysteine protease inhibitor-2 是半胱氨酸蛋白酶抑制剂。 | |||
T37693 |
N-acetyl-S-geranylgeranyl-L-Cysteine
|
Others | Others |
N-acetyl-S-geranylgeranyl-L-Cysteine is a synthetic substrate for the isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase). Because it is able to serve as a substrate for the methyltransferase, it effectively functions as an inhibitor of methylation of endogenous isoprenylated proteins. | |||
T36614 |
DL-Sulforaphane N-acetyl-L-cysteine
|
Others | Others |
Nrf2 activation of the antioxidant response element (ARE) is central to cytoprotective gene expression against oxidative and/or electrophilic stress. Unless activated by inflammatory, environmental, or oxidative stressors, Nrf2 is sequestered in the cytoplasm by its repressor, Keap1. Because of its protective capabilities, small molecules that activate Nrf2 signaling are being examined as potential anti-cancer or anti-inflammatory agents. DL-Sulforaphane N-acetyl-L-cysteine (SFN-NAC) is a major ... | |||
T34471 |
S-(3-Carboxypropyl)-L-cysteine
|
Others | Others |
S-(3-Carboxypropyl)-L-cysteine is a thioether derivative of L-cysteine. | |||
T78043 |
S-(2-Carboxyethyl)-L-cysteine
S-Carboxyethylcysteine |
||
S-(2-Carboxyethyl)-L-cysteine(S-羧乙基半胱氨酸)为一非蛋白质(改性)硫氨基酸,在Acacia种子中被发现。该化合物能够影响大鼠对种子蛋白质的利用效率,并可能抑制由蛋氨酸诱发的大鼠生长速度,同时对大鼠血浆氨基酸水平产生不利影响。 | |||
T31137 |
Cyclohexyl cysteinate
Cysteine cyclohexylester,Cysteine cyclohexyl ester |
Others | Others |
Cyclohexyl cysteinate is a bioactive chemical. | |||
T41285 |
N-Acetyl-L-cysteine ethyl ester
NACET,N-Acetylcysteine ethyl ester |
Antioxidant | oxidation-reduction |
N-Acetyl-L-cysteine ethyl ester (NACET) 是氨基酸-l-半胱氨酸的衍生物。N-Acetyl-L-cysteine ethyl ester 已被证明具有广泛的生化和生理作用,包括抑制蛋白质合成、抑制DNA 复制和诱导细胞凋亡。它还被证明具有抗炎、抗氧化和抗癌活性 | |||
T125019 |
D/L-Cysteine
|
Others | Others |
D/L-Cysteine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125019,CAS号为 3374-22-9。 | |||
T19728 |
SPRC
S-Propargyl-cysteine |
Others | Others |
SPRC is a novel synthetic molecule exerting antioxidant effects via elevating the generation of endogenous H2S. SPRC activates Gp130-mediated STAT3 and prevents doxorubicin-induced cardiotoxicity. | |||
T66872 |
(tert-Butoxycarbonyl)-D-cysteine
|
Others | Others |
(tert-Butoxycarbonyl)-D-cysteine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66872,CAS号为 149270-12-2。 | |||
T34547 |
S-Bimanylcysteine
S-Bimane-L-cysteine |
Others | Others |
S-Bimanylcysteine is a bioactive chemical. | |||
T13440 |
(RS)-Carbocisteine
S-(Carboxymethyl)-DL-cysteine |
Others | Others |
(RS)-Carbocisteine is the S-carboxymethyl cysteine. (RS)-Carbocisteine is the inactive enantiomer of Carbocisteine. | |||
T79277 |
Cysteine protease inhibitor-3
|
Parasite | Microbiology/Virology |
Cysteine protease Inhibitor-3 (Compound 15) 是抗疟作用的半胱氨酸蛋白酶抑制剂,能够有效地抑制 Pf3D7、PfW2、PfFP2 和 PfFP3,其 IC50 分别为 0.74 μM、1.05 μM、3.5 μM 和 4.9 μM。该化合物对药物敏感性和耐药性寄生虫均有效。 | |||
T31159 |
Cysteinesulfenic acid
L-Alanine, 3-sulfeno-,L-Cysteine sulfoxide,L-Cysteinesulfenic acid,S-(Propylcarbamoyl)cysteine |
Others | Others |
Cysteinesulfenic acid is a protein-sulfenic acid involved in enzyme catalysis, redox regulation, and signal transduction. | |||
T23950 |
Dacomitinib metabolite M2
Dacomitinib cysteine conjugate,UNII-SOA52D3NLL |
Others | Others |
Dacomitinib metabolite M2 is also known as Dacomitinib cysteine conjugate. Dacomitinib inhibits both the wild-type (WT) EGFR and EGFR T790M. | |||
T60559 |
S-(N-PhenethylthiocarbaMoyl)-L-cysteine
|
Others | Others |
S-(N-PhenethylthiocarbaMoyl)-L-cysteine (PEITC-Cys) 是一种抗癌剂。S-(N-PhenethylthiocarbaMoyl)-L-cysteine 具有抗白血病活性,可抑制 HL60 细胞中的 DNA 合成。S-(N-PhenethylthiocarbaMoyl)-L-cysteine 是P450的抑制剂。 | |||
T83750 |
Melittin (C-Term Cysteine labeled) TFA
Mel-Cys |
||
Melittin (C-term cysteine labeled)是一种衍生自具有细胞毒性的蜂毒肽melittin的衍生物,其在C-末端具有一个半胱氨酸残基。它能够在内体和细胞外pH条件下引发人类红细胞的溶血作用(分别在pH 5.5和7.4时的EC50s为5和6 µM)。Melittin (C-term cysteine labeled)已被用于合成膜溶解性聚合物,这些聚合物已用于体外和体内质粒递送的polyplexes的生成。 | |||
T123887 |
N-?-Glutamyl-S-(allylthio)cysteine
|
Others | Others |
N-?-Glutamyl-S-(allylthio)cysteine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T123887,CAS号为 94504-37-7。 | |||
T78587 |
Se-Methylselenocysteine hydrochloride
Methylselenocysteine hydrochloride,Se-Methylseleno-L-cysteine hydrochloride |
Beta-Secretase | Neuroscience |
Se-Methylselenocysteine hydrochloride 是一种甲基硒的前体,展现出显著的癌症化学预防和抗氧化活性。该化合物拥有优良的口服生物活性,并能有效诱导细胞凋亡(apoptosis)。 | |||
T65543 |
N-Boc-S-benzyl-D-cysteine
|
||
N-Boc-S-benzyl-D-cysteine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65543,CAS号为 102830-49-9。 | |||
T33088 |
Lysylcysteine
LYS CYS,LYS-CYS,L-Cysteine, L-lysyl-,LYSCYS |
Others | Others |
Lysylcysteine is a dipeptide composed of lysine and cysteine. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived | |||
T64782 |
L-Cysteine S-sulfate sodium salt sesquihydrate
|
Others | Others |
L-Cysteine S-sulfate sodium salt sesquihydrate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T64782,CAS号为 150465-29-5。 | |||
T65253 |
S-(Acetamidomethyl)-N-(tert-butoxycarbonyl)-L-cysteine
|
||
S-(Acetamidomethyl)-N-(tert-butoxycarbonyl)-L-cysteine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65253,CAS号为 19746-37-3。 | |||
T38206 |
3-Cysteinylacetaminophen (trifluoroacetate salt)
APAP-Cys,3-(cysteine-S-yl)acetaminophen,3-Cysteinylacetaminophen (trifluoroacetate salt) |
Others | Others |
3-Cysteinylacetaminophen is an acetaminophen-protein adduct formed during the metabolism of acetaminophen.[1],[2] 3-Cysteinylacetaminophen has been found in isolated human serum following therapeutic and supratherapeutic doses of acetaminophen and in the presence and absence of hepatotoxicity.[3],[4] In mice, 3-cysteinylacetaminophen decreases renal glutathione (GSH) levels, an effect that can be blocked by the γ-glutamyl inhibitor acivicin. | |||
T1481 |
Fudosteine
福多司坦,福多斯坦 |
Others | Others |
Fudosteine 是一种半胱氨酸衍生物和粘液活性剂。它能够抑制 MUC5AC 基因表达,阻碍 MUC5AC 粘蛋白过度分泌。 | |||
T9884 |
EN523
|
Others | Others |
EN523 靶向 K48 泛素特异性去泛素酶 OTUB1 中的非催化变构半胱氨酸 C23。 | |||
T8897 |
2-Iodoacetamide
碘乙酰胺,2-碘乙酰胺,Iodoacetamide |
Others | Others |
2-Iodoacetamide (Iodoacetamide) 是常用的烷基化剂之一,能够在蛋白质组学样品制备过程中,将半胱氨酸烷基化。 | |||
T7451 |
2-Cyanopyrimidine
2-氰基嘧啶,2-cyano-Pyrimidine |
Cysteine Protease | Proteases/Proteasome |
2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) 是半胱氨酸蛋白酶组织蛋白酶 K (cysteine protease cathepsin K) 的非选择性抑制剂(IC50:170 nM)。它能够用于骨质疏松症的研究。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2O2721 |
L-Cysteine
Thioserine,L-半胱氨酸,cysteine,半胱氨酸,L-(+)-Cysteine |
Endogenous Metabolite | Metabolism |
L-Cysteine (L-(+)-Cysteine) 是人体非必需的含硫氨基酸。L-Cysteine 对蛋白质合成、解毒和多种代谢功能很重要。L-Cysteine 存在于指甲、皮肤和头发的主要蛋白质-角蛋白中,对胶原蛋白的生成、皮肤弹性和质地都很重要。L-Cysteine 是抗氧化剂谷胱甘肽的一种成分,在辅酶A、肝素和生物素等基本生化物质的代谢中起着重要作用,也是氨基酸牛磺酸的制造所必需的。 | |||
T60237 |
L-Cysteine S-sulfate
S-Sulfo-L-cysteine |
NMDAR | Neuroscience |
L-Cysteine S-sulfate (S-Sulfo-L-cysteine) 是有效的 N-methyl-d-aspartate (NMDA) 谷氨酸受体激动剂。L-Cysteine S-sulfate 是胱氨酸裂解酶的底物。 | |||
T8141 |
L-Cysteine hydrochloride
L-Cysteine HCl,L-半胱氨酸盐酸盐,L-半胱氨酸盐酸盐(无水物) |
Others; Endogenous Metabolite | Metabolism; Others |
L-Cysteine hydrochloride (L-Cysteine HCl) 是一种条件必需氨基酸,是硫化氢 (H2S)、牛磺酸谷胱甘肽和等生物特性分子的前体。它能抑制胃饥饿素,抑制啮齿动物和人类的食欲。 | |||
TN7107 |
S-(2-Carboxypropyl)cysteine
|
Endogenous Metabolite | Metabolism |
S-(2-Carboxypropyl)cysteine 是 S-(2-Carboxypropyl)glutathione 的尿代谢产物。 | |||
TN5283 |
L-Cysteine hydrochloride hydrate
L-Cysteine hydrochloride monohydrate,L-半胱氨酸盐酸盐一水物,L-半胱氨酸盐酸盐 一水合物 |
Others; Endogenous Metabolite | Metabolism; Others |
L-Cysteine hydrochloride hydrate (L-Cysteine hydrochloride monohydrate) 是条件必需氨基酸,是硫化氢、谷胱甘肽和牛磺酸等生物活性分子的前体。它可以抑制胃饥饿素,抑制啮齿动物和人类的食欲。 | |||
T10933 |
D-Cysteine
|
Endogenous Metabolite; Antibacterial | Metabolism; Microbiology/Virology |
D-Cysteine 是一种大肠杆菌生长的有力抑制剂,是半胱氨酸的 D 型异构体。它由 D-氨基酸氧化酶介导产生 H2S,是一种对抗小脑共济失调的神经保护剂。 D-半胱氨酸可以抑制由变形链球菌和链球菌血红蛋白形成的两种生物膜的生长和致龋性。 | |||
T8072 |
S-Methyl-L-cysteine
S-甲基-L-半胱氨酸,S-Methylcysteine |
Antioxidant; Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction |
S-Methyl-L-cysteine (S-Methylcysteine) 是一种催化抗氧化系统中甲硫氨酸硫氧化物还原酶 A 的作用底物,是一种天然产物,具有抗氧化、神经保护及减肥的功效。 | |||
T2772 |
S-allyl-L-cysteine
S-Allylcysteine,S-烯丙基-L-半胱氨酸 |
Apoptosis; Others | Apoptosis; Others |
S-allyl-L-cysteine (S-Allylcysteine) 是从大蒜中发现的有机硫化物,对动物具有抗氧化和抗癌特性。 | |||
T41054 |
γ-Glutamyl-S-allylcysteine
L-γ-Glutamyl-(S)-Allyl-Cysteine |
Antioxidant | oxidation-reduction |
γ-Glutamyl-S-allylcysteine (L-γ-Glutamyl-(S)-Allyl-Cysteine) 是从Allium sativum L.中提取的γ-谷氨酰肽。γ-Glutamyl-S-allylcysteine 具有抗糖化和抗氧化活性,可抑制胆固醇的生物合成。 | |||
T0875 |
Acetylcysteine
N-Acetylcysteine,乙酰半胱氨酸,N-Acetyl-L-cysteine,LNAC,NAC,N-Acetyl Cysteine,易咳净 |
Apoptosis; TNF; Ferroptosis; Influenza Virus; Reactive Oxygen Species; ROS; Endogenous Metabolite | Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB |
Acetylcysteine (NAC) 是半胱氨酸的 N-乙酰衍生物,是一种 ROS 抑制剂和粘液溶解剂。Acetylcysteine 可诱导细胞凋亡,可用于减少粘液的厚度,还具有抗流感病毒活性。 | |||
T35710 |
N-Acetyl-S-allyl-L-cysteine
|
Others | Others |
L-Deoxyalliin , also known as S-allyl-L-cysteine, is a water soluble organosulfur compound derived from garlic that has neuroprotective and antioxidative activities. N-Acetyl-S-allyl-L-cysteine is a principal metabolite of L-deoxyalliin in humans, mice, rats, and dogs. It is readily detected in plasma and urine. The conversion of L-deoxyalliin to N-acetyl-S-allyl-L-cysteine appears to be mediated by a family of flavin-containing monooxygenases. | |||
T0983 |
Penicillamine
青霉胺,d-penicillamin,Dimethyl Cysteine,D-青霉胺,Artamine,D-(-)-Penicillamine |
Antibiotic | Microbiology/Virology |
Penicillamine (Artamine) 是一种 penicillin 的代谢降解产物,是一种螯合剂,可作用于威尔逊氏病。 | |||
T12789 |
S-1-Propenyl-L-cysteine
|
Others | Others |
S-1-Propenyl-L-cysteine, a stereoisomer of S-allyl-l-cysteine, exhibits immunomodulatory effects and has been shown to decrease blood pressure in hypertensive animal models. | |||
T13698 |
γ-Glutamyl-S-1-propenyl cysteine
|
Others | Others |
γ-Glutamyl-S-1-propenyl cysteine is a compound isolated from garlic. | |||
T10025 |
1-PeCSO
S-1-Propenyl-L-cysteine sulfoxide |
Others | Others |
1-PeCSO is isolated from onion or garlic bulbs. It acts as a key compound in garlic greening and reacts with lachrymatory factor synthase. | |||
T80679 |
γ-L-Glutamyl-S-allyl-L-cysteine
|
||
γ-L-Glutamyl-S-allyl-L-cysteine为一有机硫化合物,其天然分布于大蒜中。 | |||
T83538 |
(R)-1-PeCSO
Isoalliin,trans-(+)-S-1-Propenyl-L-cysteine sulfoxide |
||
(R)-1-PeCSO(trans-(+)-S-1-Propenyl-L-cysteine sulfoxide)作为洋葱中味道前体的主要成分,含量丰富。 | |||
T5968 |
DL-Homocysteine thiolactone hydrochloride
DL-Homocysteinethiolactone hydrochloride,DL-高半胱氨酸硫内酯盐酸盐 |
Endogenous Metabolite | Metabolism |
DL-Homocysteine thiolactone hydrochloride (DL-Homocysteinethiolactone hydrochloride) 是具有根生长抑制特性的环状氨基酸衍生物。 | |||
T4863 |
DL-Homocysteine
DL-高半胱氨酸,2-Amino-4-mercaptobutyric acid |
Endogenous Metabolite | Metabolism |
DL-Homocysteine (2-Amino-4-mercaptobutyric acid) 是弱神经毒素,能够影响犬尿酸的产生。 | |||
T7727 |
Se-Methylselenocysteine
Se MSC,SeMCys,MSeC,L-硒甲基硒代半胱氨酸,Se-MSC,SeMSC |
BCL; IAP; Caspase | Apoptosis; Proteases/Proteasome |
Se-Methylselenocysteine (Se-MSC) 是具有口服活性的甲基硒前体,具有强大的抗氧化活性和抗癌活性。Se-Methylselenocysteine 可诱导细胞凋亡。 | |||
T19392 |
L-Homocysteine
|
Others | Others |
L-Homocysteine, an L-configured homocysteine metabolite, induces the upregulation of cathepsin V, which mediates vascular endothelial inflammation in hyperhomocysteinaemia. | |||
T38024 |
Gamma-glutamylcysteine
|
Others | Others |
Gamma-glutamylcysteine 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 T38024,CAS号为 636-58-8。 | |||
T11803 |
L-Cysteinesulfinic acid
|
Others | Others |
L-Cysteinesulfinic acid is a potent agonist at several rat metabotropic glutamate receptors (mGluRs, pEC50s of 3.92±0.03, 4.6±0.2, 3.9±0.2, 2.7±0.2, 4.0±0.2, and 3.94±0.08 for mGluR1, mGluR5, mGluR2, mGluR4, mGluR6, and mGluR8, respectively). | |||
T8095 |
O-Acetylserine
O-乙酰-L-丝氨酸,O-Acetyl-L-serine,O-乙醯絲胺酸 |
Others; Endogenous Metabolite | Metabolism; Others |
O-Acetylserine (O-Acetyl-L-serine) 是细菌和植物中半胱氨酸合成过程中的中间体。 | |||
T1085L |
Glutathione oxidized
Bi(glutathion-S-yl),Oxidized glutathione,L-谷胱甘肽(氧化型),氧化型谷胱甘肽,L-Glutathione oxidized,Glutathione disulfide,L(-)-Glutathione,GSSG |
Reactive Oxygen Species; Endogenous Metabolite; Glutathione reductase | Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction |
Glutathione oxidized (L(-)-Glutathione) 是氧化型谷胱甘肽,谷胱甘肽是细胞内一种主要的抗氧化剂和解毒剂。 | |||
T19503 |
Papain
|
Others; Cysteine Protease | Others; Proteases/Proteasome |
Papain 是一种半胱氨酸蛋白酶,是肽酶 C1 家族中一员,在食品、医药、化妆品、纺织等具有广泛的应用。 | |||
T5083 |
L-Cysteic acid monohydrate
L-磺基丙氨酸 一水合物,3-Sulfo-L-alanine Monohydrate |
Endogenous Metabolite; GluR | Metabolism; Neuroscience |
L-Cysteic acid monohydrate (3-Sulfo-L-alanine Monohydrate) 是内源性代谢产物的一种。 | |||
T5085 |
Pyridoxal 5'-phosphate hydrate
Codecarboxylase,Pyridoxal 5'-phosphate hydrate(1:x),5-磷酸吡多醛水合物,PLP,Pyridoxal 5'-phosphate hydrate |
Others; Endogenous Metabolite | Metabolism; Others |
Pyridoxal 5'-phosphate hydrate (PLP) 是内源性代谢产物的一种。 | |||
T5225 |
Hypotaurine
2-Aminoethanesulfinic acid,亚牛磺酸,2-Aminoethylsulfinic acid |
Chloride channel; Endogenous Metabolite | Membrane transporter/Ion channel; Metabolism |
Hypotaurine (2-Aminoethanesulfinic acid) 是星形胶质细胞中半胱氨酸生物合成的牛磺酸中间体,是甘氨酸受体 (glycine receptor) 的内源性抑制性氨基酸。Hypotaurine 也是抗氧化剂。 | |||
T4722 |
O-Acetyl-L-serine hydrochloride
|
Others; Endogenous Metabolite | Metabolism; Others |
O-Acetyl-L-serine hydrochloride 是内源性代谢产物的一种。 | |||
T5276 |
4,4'-Disulfanediylbis(2-aminobutanoic acid)
DL-Homocystine,DL-高胱氨酸 |
Others; Endogenous Metabolite | Metabolism; Others |
4,4'-Disulfanediylbis(2-aminobutanoic acid) (DL-Homocystine) 是内源性代谢产物的一种。 | |||
T7094 |
Levomefolic Acid
L-5-甲基四氢叶酸,5-MTHF,5-甲基四氢叶酸 |
Reactive Oxygen Species; Endogenous Metabolite | Immunology/Inflammation; Metabolism; NF-κB |
Levomefolic Acid (5-MTHF) 是一种具有口服活性、可穿过血脑屏障的天然活性叶酸,是广泛使用的叶酸食品补充剂。 | |||
T10857 |
Coenzyme A
|
Endogenous Metabolite | Metabolism |
Coenzyme A 是所有活细胞中必需的辅助因子,由泛酸,三磷酸腺苷和半胱氨酸合成的。Coenzyme A 与过氧化物酶 5 共价结合导致其过氧化物酶活性完全抑制,通过 DTT 还原能够逆转。Coenzyme A 及其硫酯衍生物是主要分解代谢,合成代谢途径和基因表达调控的关键参与者。 | |||
T8274 |
3-Methyl-L-histidine
|
Endogenous Metabolite | Metabolism |
3-Methyl-L-histidine 是一种肉类尤其是鸡肉摄入和大豆制品摄入的生物标记。 | |||
T2768 |
Saikosaponin A
柴胡皂苷A,柴胡皂苷 A |
NF-κB; Antibacterial; Liver X Receptor | Metabolism; Microbiology/Virology; NF-κB |
Saikosaponin A 是银柴胡中的主要活性成分,有抗炎活性,可上调 LXRα的表达。 | |||
T2O2733 |
L-Cystine
Cystine Acid,cystine,胱氨酸,L-胱氨酸 |
Antioxidant; Ferroptosis; Endogenous Metabolite | Apoptosis; Metabolism; oxidation-reduction |
L-Cystine (Cystine Acid) 是一种从半胱氨酸氨基酸硫醇侧链氧化获得的含硫衍生物。它起到抗氧化剂的作用,保护组织免受辐射和污染,减缓衰老过程。它还有助于蛋白质合成。 | |||
T4909 |
N-Acetyl-DL-methionine
N-乙酰-DL-蛋氨酸,N-乙酰-DL-甲硫氨酸 |
Others; Endogenous Metabolite | Metabolism; Others |
N-Acetyl-DL-methionine 是内源性代谢产物的一种。 | |||
T4889 |
2,6-Diaminoheptanedioic acid
|
Others; Endogenous Metabolite | Metabolism; Others |
2,6-Diaminoheptanedioic acid 是内源性代谢产物的一种。 | |||
TQ0208 |
SAH
SAH (S-Adenosylhomocysteine),S-(5'-腺苷)-L-高半胱氨酸 |
Others; Endogenous Metabolite | Metabolism; Others |
SAH (S-Adenosylhomocysteine) 属于氨基酸衍生物,是腺苷和半胱氨酸合成的中间体。SAH 是一种 METTL3-METTL14 异二聚体复合物的抑制剂 (IC50=0.9 µM)。SAH 是多种代谢途径中的调节剂。 | |||
T72901 |
Indolokine A5
|
Others | Others |
Indolokine A5, L-半胱氨酸的分解代谢物, 是一种有效的AhR 激动剂。 | |||
T79978 |
6,6′-Dihydroxythiobinupharidine
|
Others | Others |
6,6′-Dihydroxythiobinupharidine 作为一种抑制剂,主要针对半胱氨酸蛋白酶(cysteine proteases)。研究表明,该化合物能显著促进人拓扑异构酶IIα(topoisomeraseIIα)和IIβ(topoisomeraseIIβ)介导的DNA裂解,分别提高了8倍和3倍的效率。 | |||
T15467 |
Helenalin
|
Others | Others |
Helenalin is a selective inhibitor of transcription factor NF-κB by direct targeting of p65. It is an anti-inflammatory sesquiterpene lactone compound with alkylating activity. Through its ability to target the cysteine sulfhydryl groups in the p65 subunit of NF-κB, helenalin effectively inhibits its DNA binding. | |||
TN5240 |
Vitedoin A
|
Others | Others |
Vitedoin A shows stronger antioxidative activity than alpha-tocopherol using the ferric thiocyanate method, it also shows higher radical-scavenging effect on the stable free radical, 1,1-diphenyl-2-picrylhydrazyl, than L-cysteine. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00602 |
MetC Protein, E. coli, Recombinant (His)
Cysteine lyase MetC,Beta-cystathionase MetC,metC,Cy... |
E. coli | E. coli |
Primarily catalyzes the cleavage of cystathionine to homocysteine, pyruvate and ammonia during methionine biosynthesis. Also exhibits cysteine desulfhydrase activity, producing sulfide from cysteine. In addition, under certain growth conditions, exhibits significant alanine racemase coactivity. | |||
TMPJ-01142 |
CDO1 Protein, Human, Recombinant (His)
CDO-I,CDO,Cysteine Dioxygenase Type I,CDO1,Cyst... |
Human | E. coli |
Cysteine Dioxygenase Type 1 (CDO1) is a mammalian non-heme iron enzyme that belongs to the cysteine dioxygenase family. CDO1 is highly expressed in the liver and placenta, and has a low expression in heart, brain and pancreas. CDO1 can also be detected in hepatoblastoma HepG2 cells. CDO1 catalyzes the conversion of L-cysteine to cysteine sulfinic acid by incorporation of dioxygen. CDO1 is a vital regulator of cellular cysteine concentrations and has an essential role in maintaining the hepatic c... | |||
TMPJ-01250 |
ATG4A Protein, Human, Recombinant (His)
ATG4A,Autophagin-2,AUT-Like 2 Cysteine Endopeptidas... |
Human | E. coli |
Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy; it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers. | |||
TMPH-00691 |
IscS Protein, E. coli O6:K15:H31, Recombinant (His & Myc & SUMO)
Cysteine desulfurase IscS,iscS |
E. coli | E. coli |
IscS Protein, E. coli O6:K15:H31, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 65.1 kDa and the accession number is Q0TEV5. | |||
TMPH-03648 |
Cruzipain Protein, Trypanosoma cruzi, Recombinant (His & Myc)
Cruzaine,Cruzipain,Major cysteine proteinase |
Trypanosoma cruzi | E. coli |
Hydrolyzes chromogenic peptides at the carboxyl Arg or Lys; requires at least one more amino acid, preferably Arg, Phe, Val or Leu, between the terminal Arg or Lys and the amino-blocking group.; The cysteine protease may play an important role in the development and differentiation of the parasites at several stages of their life cycle. Cruzipain Protein, Trypanosoma cruzi, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weig... | |||
TMPY-04814 |
SPARC Protein, Rat, Recombinant (His)
SPARC,secreted protein, acidic, cysteine-rich (oste... |
Rat | HEK293 Cells |
SPARC Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.8 kDa. | |||
TMPH-02616 |
CSAD Protein, Mouse, Recombinant (His & SUMO)
Csad,Cysteine sulfinic acid decarboxylase,Cyste... |
Mouse | E. coli |
Catalyzes the decarboxylation of L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respectively. The preferred substrate is 3-sulfino-L-alanine. Does not exhibit any decarboxylation activity toward glutamate. | |||
TMPH-00392 |
Small-CRP Protein, Chlamydia trachomatis, Recombinant (His & SUMO)
omcA,Small cysteine-rich outer membrane protein Omc... |
Chlamydia trachomatis | E. coli |
In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the large cysteine-rich periplasmic protein and the major outer membrane porin. It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan. Small-CRP Protein, Chlamydia trachomatis, Recombinant (His & SUMO) is... | |||
TMPH-00389 |
OmcB Protein, Chlamydia trachomatis, Recombinant (His & SUMO)
Large cysteine-rich periplasmic protein OmcB,Cy... |
Chlamydia trachomatis | E. coli |
In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the major outer membrane protein. It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan. OmcB Protein, Chlamydia trachomatis, Recombinant (His & SUMO) is expressed in E... | |||
TMPH-01177 |
CRISPLD2 Protein, Human, Recombinant (His & Myc)
CRISP11,LCCL domain-containing cysteine-rich secret... |
Human | HEK293 Cells |
CRISPLD2 Protein, Human, Recombinant (His & Myc) is expressed in HEK293. | |||
TMPH-02414 |
Lys-gingipain W83 Protein, Porphyromonas gingivalis, Recombinant (His)
Lys-gingipain W83,Lysine-specific cysteine proteina... |
Porphyromonas gingivalis | E. coli |
Lys-gingipain W83 Protein, Porphyromonas gingivalis, Recombinant (His) is expressed in E. coli expression system with C-10xHis tag. The predicted molecular weight is 51.6 kDa and the accession number is Q51817. | |||
TMPJ-00014 |
Resistin Protein, Human, Recombinant (His)
Resistin,C/EBP-epsilon-regulated myeloid-specific secreted <... |
Human | E. coli |
Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. The length of the resistin pre-peptide in human is 108 amino acid residues and in the mouse and rat it is 114 aa; the molecular weight is ~12.5 kDa. Resistin is a cytokine whose physiologic role has been the subject of much controversy regarding its involvement wit... | |||
TMPY-03454 |
CRELD1 Protein, Mouse, Recombinant (His)
cysteine-rich with EGF-like domains 1,AI843811 |
Mouse | HEK293 Cells |
CRELD1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.7 kDa and the accession number is Q91XD7. | |||
TMPH-00134 |
AcMNPV Viral cathepsin Protein (His & SUMO)
Cysteine proteinase,Viral cathepsin,VCATH,V-cath |
AcMNPV | E. coli |
Cysteine protease that plays an essential role in host liquefaction to facilitate horizontal transmission of the virus. Accumulates within infected cells as an inactive proenzyme (proV-CATH), which is activated by proteolytic cleavage upon cell death. AcMNPV Viral cathepsin Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 39.9 kDa and the accession number is P25783. | |||
TMPY-03750 |
CRIPT Protein, Human, Recombinant (His)
HSPC139,SSMDF,cysteine-rich PDZ-binding protein |
Human | E. coli |
CRIPT, also known as cysteine-rich PDZ-binding protein, belongs to the CRIPT family. It interacts with TUBB1. CRIPT also interacts strongly with the PDZ3 domain of members of the DLG4 family. It is involved in the cytoskeletal anchoring of DLG4 in excitatory synapses. CRIPT is highly conserved from mammals to plants and binds selectively to the third PDZ domain (PDZ3) of PSD-95 via its C terminus. n heterologous cells, CRIPT causes a redistribution of PSD-95 to microtubules. In brain, CRIPT colo... | |||
TMPY-01824 |
Caspase-14 Protein, Human, Recombinant (His)
caspase 14, apoptosis-related cysteine peptidase,AR... |
Human | E. coli |
Caspase 14 is a member of the caspase family. Caspases are a kind of cysteine proteinase consisting of a prodomain plus large and small catalytic subunits, that play a central role in cell apoptosis. Caspase 14 possesses an unusually short prodomain and is highly expressed in embryonic tissues but absent from most of the adult tissues except for the skin, which suggests a role in ontogenesis and skin physiology. Unlike the other short prodomain caspases(caspase-3, caspase-6, and caspase-7), Casp... | |||
TMPY-03342 |
CRIP2 Protein, Human, Recombinant (His & GST)
CRIP,ESP1,CRP2,cysteine-rich protein 2 |
Human | Baculovirus Insect Cells |
CRIP2 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 50.3 kDa and the accession number is P52943. | |||
TMPY-03218 |
CRELD1 Protein, Human, Recombinant (His)
cysteine-rich with EGF-like domains 1,CIRRIN,AVSD2 |
Human | HEK293 Cells |
CRELD1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.4 kDa and the accession number is A0A024R2G1. | |||
TMPY-00420 |
CRELD1 Protein, Mouse, Recombinant (hFc)
cysteine-rich with EGF-like domains 1,AI843811 |
Mouse | HEK293 Cells |
CRELD1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 63 kDa and the accession number is Q91XD7. | |||
TMPY-04132 |
CRISP1 Protein, Mouse, Recombinant (hFc)
Aeg1,CRISP-1,AW324342,cysteine-rich secretory prote... |
Mouse | HEK293 Cells |
CRISP1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.4 kDa and the accession number is Q03401. | |||
TMPH-02432 |
Legumain Protein, Cynomolgus, Recombinant (E. coli, His & Myc)
Legumain,Protease, cysteine 1,LGMN,Asparaginyl endo... |
Cynomolgus | E. coli |
Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation. May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. Legumain Protein, Cynomolg... | |||
TMPY-03459 |
CRIP2 Protein, Human, Recombinant
CRP2,cysteine-rich protein 2,ESP1,CRIP |
Human | Baculovirus Insect Cells |
CRIP2 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 22.6 kDa and the accession number is P52943. | |||
TMPH-02748 |
KCP Protein, Mouse, Recombinant (His & Myc)
Kcp,Cysteine-rich BMP regulator 2,Kielin/chordin-li... |
Mouse | E. coli |
Enhances bone morphogenetic protein (BMP) signaling in a paracrine manner. In contrast, it inhibits both the activin-A and TGFB1-mediated signaling pathways. KCP Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 44.7 kDa and the accession number is Q3U492. | |||
TMPY-00448 |
CRELD2 Protein, Mouse, Recombinant (hFc)
5730592L21Rik,cysteine-rich with EGF-like domains 2... |
Mouse | HEK293 Cells |
CRELD2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.8 kDa and the accession number is Q9CYA0. | |||
TMPH-03577 |
Staphopain B Protein, S. aureus, Recombinant (GST)
Staphopain B,sspB,Staphylopain B,Staphylococcal cysteine... |
Staphylococcus aureus | E. coli |
Cysteine protease that plays an important role in the inhibition of host innate immune response. Degrades host elastin, fibrogen, fibronectin and kininogen. Blocks phagocytosis of opsonised S. aureus by neutrophils and monocytes by inducing their death in a proteolytic activity-dependent manner. Decreases surface expression of the 'don't eat me' signal CD31 on neutrophils. Cleaves host galectin-3/LGALS3, thereby inhibiting the neutrophil-activating ability of the lectin. Staphopain B Protein, S.... | |||
TMPH-00629 |
Gamma-GCS Protein, E. coli, Recombinant (His & SUMO)
Glutamate--cysteine ligase,Gamma-ECS,gshA,Gamma-glu... |
E. coli | E. coli |
N/A. Gamma-GCS Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 74.3 kDa and the accession number is P0A6W9. | |||
TMPJ-01197 |
CRELD2 Protein, Human, Recombinant (His)
Cysteine-Rich With EGF-Like Domain Protein 2,CRELD2 |
Human | HEK293 Cells |
Cysteine-Rich with EGF-Like Domain Protein 2 (CRELD2) is a secreted protein that is a member of the CRELD family. Human CRELD2 is synthesized as a 353 amino acid precursor protein with a signal peptide, a highly conserved domain rich in glutamic acid and tryptophan (WE) and EGF-like repeats. CRELD2 is ubiquitously expressed in many tissues. CRELD2 may interact with CHRNA4 and regulate transport of α4-β2 neuronal acetylcholine receptor. In addition, CRELD2 could be a novel mediator in regulating ... | |||
TMPJ-01364 |
LMCD1 Protein, Human, Recombinant (His)
LMCD1,Dyxin,LIM and cysteine-rich domains protein 1 |
Human | E. coli |
LMCD1 is transcriptional cofactor which contains a cysteine-rich domain in the N-terminal region and 2 LIM domains in the C-terminal region. It also has several potential phosphorylation and N-myristoylation sites and a single potential N-glycosylation site. LMCD1 is expressed in many tissues with highest abundance in skeletal muscle. LMCD1 restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. It plays a critic... | |||
TMPH-02431 |
Legumain Protein, Cynomolgus, Recombinant (His & Myc)
Legumain,Protease, cysteine 1,Asparaginyl endopepti... |
Cynomolgus | Baculovirus Insect Cells |
Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation. May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. Legumain Protein, Cynomolg... | |||
TMPY-04934 |
Serpin A3n Protein, Rat, Recombinant (His)
serine (or cysteine) peptidase inhibitor, clade A, ... |
Rat | HEK293 Cells |
Serpina3n may represent a circulating biomarker of muscle atrophy associated with GC and, broadly, a reflection of dynamic changes in muscle mass. Serpina3n blocks endogenous increases in the activity of select skeletal muscle resident proteases during injury or dystrophic disease, which stabilizes the sarcolemma leading to less myofiber degeneration and increased regeneration. | |||
TMPH-00060 |
ApNPV Viral cathepsin Protein (His & Myc)
V-cath,Viral cathepsin,Cysteine proteinase (CP),VCA... |
ApNPV | E. coli |
Cysteine protease that plays an essential role in host liquefaction to facilitate horizontal transmission of the virus. May participate in the degradation of foreign protein expressed by the baculovirus system. ApNPV Viral cathepsin Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 31.1 kDa and the accession number is Q91CL9. | |||
TMPH-00821 |
EP-B2 Protein, Hordeum vulgare, Recombinant (His & SUMO)
Cysteine proteinase EP-B 2,EP-B2,EPB2 |
Hordeum vulgare | E. coli |
EP-B2 Protein, Hordeum vulgare, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 41.3 kDa and the accession number is P25250. | |||
TMPH-03156 |
Lys-gingipain Protein, Porphyromonas gingivalis, Recombinant (His & SUMO)
Lysine-specific cysteine proteinase Kgp,Lys-gingipa... |
Porphyromonas gingivalis | E. coli |
Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the functions of polymorphonuclear leukocytes. May act as a virulence factor in the development of peridontal disease. Involved in the coaggregation of P.gingivalis with other oral bacteria. Lys-gingipain Protein, Porphyromonas gingivalis, Recombinant (His & SUMO) is expressed in E. col... | |||
TMPY-03494 |
CRELD2 Protein, Mouse, Recombinant (His)
5730592L21Rik,cysteine-rich with EGF-like domains 2... |
Mouse | HEK293 Cells |
CRELD2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.5 kDa and the accession number is Q9CYA0. | |||
TMPH-02027 |
RETNLB Protein, Human, Recombinant (His)
Colon carcinoma-related gene protein,Colon and small intesti... |
Human | E. coli |
Probable hormone. RETNLB Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 13.4 kDa and the accession number is Q9BQ08. | |||
TMPY-00449 |
CRISP1 Protein, Mouse, Recombinant (His)
AW324342,cysteine-rich secretory protein 1,Aeg1,CRI... |
Mouse | HEK293 Cells |
CRISP1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.1 kDa and the accession number is Q03401. | |||
TMPH-01176 |
CSRP3 Protein, Human, Recombinant (His & SUMO)
CLP,CRP,Muscle LIM protein,CSRP3,Cardiac LIM protein,Cys... |
Human | E. coli |
CSRP3 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPY-01182 |
SPARC Protein, Human, Recombinant (His)
BM-40,ON,SPARC,secreted protein, acidic, cysteine-r... |
Human | HEK293 Cells |
SPARC Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34 kDa and the accession number is P09486. | |||
TMPJ-00939 |
CTH Protein, Human, Recombinant
γ-Cystathionase,Cystathionine γ-Lyase,Cystathionine Gamma-Ly... |
Human | E. coli |
Cystathionine Gamma-Lyase (CTH) belongs to the trans-sulfuration enzymes family. CTH exists as a homotetramer and interacts with CALM in a calcium-dependent manner. CTH breaks down cystathionine into cysteine, ammonia and 2-oxobutanoate. CTH catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine and has broad substrate specificity. Defects in CTH will lead to cystathioninuria, which is an autosomal recessive phenotype characterized by abnormal accumulation of plasma... | |||
TMPY-05214 |
CRISP3 Protein, Human, Recombinant (His)
SGP28,CRS3,CRISP-3,cysteine-rich secretory protein ... |
Human | HEK293 Cells |
CRISP3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.9 kDa and the accession number is P54108.1. | |||
TMPH-00101 |
PDLP7 Protein, Arabidopsis thaliana, Recombinant (His & SUMO)
PDLP7,Cysteine-rich repeat secretory protein 60,Pla... |
Arabidopsis thaliana | E. coli |
Modulates cell-to-cell trafficking. PDLP7 Protein, Arabidopsis thaliana, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 41.3 kDa and the accession number is Q0WPN8. | |||
TMPH-03576 |
Staphopain A Protein, S. aureus, Recombinant (His & Myc)
Staphopain A,Staphylopain A,sspP,Staphylococcal cysteine... |
Staphylococcus aureus | E. coli |
Staphopain A Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 27.4 kDa and the accession number is P81297. | |||
TMPH-03231 |
AFP2 Protein, Raphanus sativus, Recombinant (His & SUMO)
Cysteine-rich antifungal protein 2,Defensin-like pr... |
Raphanus sativus | E. coli |
Possesses antifungal activity sensitive to inorganic cations. Induces potential changes in fungal membranes and increased K(+) efflux and Ca(2+) uptake. AFP2 Protein, Raphanus sativus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 21.7 kDa and the accession number is P30230. | |||
TMPH-00370 |
GAPDH Protein, Chicken, Recombinant (His)
Peptidyl-cysteine S-nitrosylase GAPDH,GAPDH,Glycera... |
Chicken | E. coli |
GAPDH Protein, Chicken, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 39.6 kDa and the accession number is P00356. | |||
TMPH-00439 |
GAPDH Protein, Cricetulus griseus, Recombinant (His)
Glyceraldehyde-3-phosphate dehydrogenase,Peptidyl-cystei... |
Chinese hamster | E. coli |
GAPDH Protein, Cricetulus griseus, Recombinant (His) is expressed in E. coli. | |||
TMPY-01562 |
CSRP1 Protein, Human, Recombinant (His)
cysteine and glycine-rich protein 1,D1S181E,CRP1,CY... |
Human | E. coli |
CSRP1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 21.4 kDa and the accession number is A0A384P5K2. | |||
TMPY-01796 |
SPARC Protein, Mouse, Recombinant (His)
AA517111,secreted protein, acidic, cysteine-rich (o... |
Mouse | HEK293 Cells |
SPARC Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34 kDa and the accession number is P07214. | |||
TMPY-01632 |
Serpin B4 Protein, Mouse, Recombinant (His)
Serpinb4,1110001H02Rik,1110013A16Rik,Serpinb3c,Scca2,serine ... |
Mouse | Baculovirus Insect Cells |
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhi... | |||
TMPH-00460 |
Defensin-like protein 1 Protein, Dahlia merckii, Recombinant (B2M & His)
DmAMP1,Defensin-like protein 1,Cysteine-rich antimi... |
Dahlia merckii | E. coli |
Defensin-like protein 1 Protein, Dahlia merckii, Recombinant (B2M & His) is expressed in E. coli. | |||
TMPY-02235 |
CSRP1 Protein, Mouse, Recombinant (His)
cysteine and glycine-rich protein 1,CRP1,AA959891,C... |
Mouse | E. coli |
CSRP1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22 kDa and the accession number is P97315. | |||
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Cat. No. | Product Name | Target | Signaling Pathways |
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TMIJ-0384 |
L-Cysteine-d3
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L-Cysteine-d3 是 L-Cysteine 的氘代化合物。L-Cysteine 的 CAS 号为 52-90-4。L-Cysteine 是人体非必需的含硫氨基酸。L-Cysteine 对蛋白质合成、解毒和多种代谢功能很重要。L-Cysteine 存在于指甲、皮肤和头发的主要蛋白质-角蛋白中,对胶原蛋白的生成、皮肤弹性和质地都很重要。L-Cysteine 是抗氧化剂谷胱甘肽的一种成分,在辅酶A、肝素和生物素等基本生化物质的代谢中起着重要作用,也是氨基酸牛磺酸的制造所必需的。 | |||
TMID-0121 |
DL-Homocysteine-3,3,4,4-d4
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DL-Homocysteine-3,3,4,4-d4 是 DL-Homocysteine 的氘代化合物。DL-Homocysteine 的 CAS 号为 454-29-5。DL-Homocysteine 是弱神经毒素,能够影响犬尿酸的产生。 | |||
TMIJ-0302 |
Esomeprazole-d3
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Esomeprazole-d3 是 Esomeprazole 的氘代化合物。Esomeprazole 的 CAS 号为 119141-88-7。Esomeprazole 是奥美拉唑(omeprazole) 的S-异构体,抑制溶酶体半胱氨酸蛋白酶legumain,防止癌症转移。它是一种质子泵抑制剂(PPI)。 | |||
TMIJ-0375 |
Levomefolic Acid-13C-d3
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Levomefolic Acid-13C-d3 是 Levomefolic Acid 的 13C 和氘代化合物。Levomefolic Acid 的 CAS 号为 31690-09-2。Levomefolic acid是一种具有口服活性、可穿过血脑屏障的天然活性叶酸,是广泛使用的叶酸食品补充剂。 | |||
T35789 |
Palmitic acid-1-13C
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Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.1 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.2 Palmitic acid is involved in the acylation of proteins to anchor membrane-bound proteins to the lipid bilayer.2,3,4,5,6 |1. Santos, M.J., López-Jurado, M., Llopis, J., et a... | |||
T35791 |
Palmitic acid-13C
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Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid-13C contains 13C at the C2 position and has been used in the study of free fatty acid incorporation into phospholipid fatty acids in soil microbes.1 Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.2 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.3 Palmitic ... |