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TMPY-02956
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Apolipoprotein L/APOL1 Protein, Human, Recombinant (His)
APOL1,apolipoprotein L1,APOL<...
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Human
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Baculovirus Insect Cells
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APOL1, also known as apolipoprotein L1, is a minor apoprotein component of HDL (High-density lipoprotein) or 'good cholesterol' which is synthesized in the liver and also in many other tissues, including pancreas, kidney, and brain. APOL1 belongs to the apolipoprotein L family. It may play a role in lipid exchange and transport throughout the body. It may also participate in reverse cholesterol transport from peripheral cells to the liver. Defects in APOL1 are the cause of focal segmental glomer... |
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TMPY-02219
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Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)
NS1 Protein
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H1N1
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E. coli
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The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the NS2 protein, which mediates the export of vRNPs. The non-structural (NS1) protein is found in Influenzavirus A, Influenzavirus B, and Influenzavirus C. The non-structural (NS1) protein of the highly pathogenic avian H5N1 viruses circulating in poultry and waterfowl in Southeast As... |
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TMPH-01595
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KMO Protein, Human, Recombinant (His)
Kynurenine 3-monooxygenase,KMO,Kynurenine 3-hydroxyl
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Human
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E. coli
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Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract (Probable). |
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TMPJ-00508
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CTSL Protein, Human, Recombinant (His)
CTSL,CTSL1,Cathepsin L1,Major Exc...
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Human
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HEK293 Cells
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Cathepsin L is an enzyme. Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L plays a major role in antigen processing, tumor invasion and metastasis, bone resorption, and turnover of intracellular and secreted proteins involved in growth regulation. Unlike the precursor forms of other papain family members, the 43 kDa pro-cathepsin L itself is secreted from various cells. Pro-cathepsin L is the maj... |
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TMPY-05561
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L-selectin Protein, Human, Recombinant (His)
selectin L,LSEL,L
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Human
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CHO Cells
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L-selectin Protein, Human, Recombinant (His) is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 35.6 kDa and the accession number is P14151-1. |
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TMPY-04256
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L-selectin Protein, Cynomolgus, Recombinant (hFc)
selectin L
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Cynomolgus
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HEK293 Cells
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L-selectin Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.1 kDa and the accession number is Q95198. |
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TMPY-00734
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Cathepsin L Protein, Human, Recombinant (His)
MEP,CTSL1,CTSL,cathepsin L,FL...
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Human
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HEK293 Cells
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Cathepsin L Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is A0A024R276. |
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TMPY-06595
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L-selectin Protein, Rhesus, Recombinant (His)
selectin L
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Rhesus
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HEK293 Cells
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L-selectin Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.6 kDa. |
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TMPY-02171
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Cathepsin L Protein, Mouse, Recombinant (His)
Ctsl1,1190035F06Rik,nkt,cathepsin L,MEP,fs
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Mouse
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HEK293 Cells
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Cathepsin L Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is P06797. |
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TMPY-02024
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L-selectin Protein, Human, Recombinant (HEK293,His)
LECAM1,TQ1,CD62L,LYAM1,L...
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Human
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HEK293 Cells
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L-selectin Protein, Human, Recombinant (HEK293,His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.5 kDa and the accession number is P14151-1. |
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TMPY-01184
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L-selectin Protein, Mouse, Recombinant (His)
Ly-22,selectin L,Lnhr,
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Mouse
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HEK293 Cells
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L-selectin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.7 kDa and the accession number is P18337. |
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TMPY-06594
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L-selectin Protein, Rhesus, Recombinant (hFc)
selectin L
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Rhesus
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HEK293 Cells
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L-selectin Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.1 kDa and the accession number is Q95198. |
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TMPY-05170
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L-selectin Protein, Rat, Recombinant (His)
selectin L
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Rat
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HEK293 Cells
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L-selectin Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.8 kDa and the accession number is Q63762. |
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TMPY-00914
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L-selectin Protein, Mouse, Recombinant (His & hFc)
L-selectin,selectin L,CD...
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Mouse
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HEK293 Cells
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L-selectin Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 61 kDa and the accession number is P18337. |
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TMPH-00780
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CACNA1C Protein, Guinea Pig, Recombinant (His)
CACNA1C,CACNL1A1,CACH2,CACN2,Voltage-depen...
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Guinea pig
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E. coli
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Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Mediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm. Plays an important role in excitation-contraction coupling in the heart. Required for normal heart development and normal regulation of heart rhythm. Required for normal contraction of smooth muscle cells in blood vessels and in the intestine. Essential for normal blood pressur... |
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TMPK-00865
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TM4SF1 Protein-VLP, Human, Recombinant
TAAL6,L6,H-L6,M3S1
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Human
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HEK293 Cells
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Transmembrane-4-L-six-family-1(TM4SF1), a four-transmembrane L6 family member, is highly expressed in various pancreatic cancer cell lines and promotes cancer cells metastasis. It is upregulated in several epithelial cancers and is closely associated with poor prognosis. |
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TMPY-03987
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T Plastin/PLS3 Protein, Human, Recombinant (His)
BMND18,T-plastin,plastin 3
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Human
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E. coli
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PLS3, also known as plastin 3, belongs to the plastin family. Members of this family are actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. There are two ubiquitous plastin isoforms in humans: L and T. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, m... |
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TMPJ-00979
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GSH-S Protein, Human, Recombinant (His)
Glutathione Synthetase,GSS,GSH-S,GSH Synthetase,G
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Human
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E. coli
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Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the secon... |
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TMPH-02524
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Arginase-1/ARG1 Protein, Mouse, Recombinant (His)
Arginase-1,Type I arginase,Liver-type arginase,Arg1
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Mouse
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P. pastoris (Yeast)
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Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively; the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys.; Functions in L-arginine homeostasis in nonhepatic tissues characterized by the competition between nitric oxide synthase (NOS) and arginase for the available i... |
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TMPK-00830
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P-Selectin Protein, Human, Recombinant (Avi & His), Biotinylated
FLJ45155,CD62P,GRMP,CD62,P-Selectin,PSE
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Human
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HEK293 Cells
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Human P-Selectin (GMP-140, LECAM-3, PADGEM, CD62P), a member of the Selectin family, is a cell surface glycoprotein expressed by activated platelets and endothelial cells. A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. |
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TMPJ-00612
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PSGL-1/CD162 Protein, Mouse, Recombinant (aa 42-307, hFc)
CLA,PSGL1,CD162,PSGL-1
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Mouse
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HEK293 Cells
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P-selectin glycoprotein ligand 1 is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 ... |
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TMPJ-00708
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CST7 Protein, Mouse, Recombinant (His)
CMAP,Cystatin-7,Leukocystatin,Cystatin-lik...
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Mouse
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HEK293 Cells
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Mouse Cystatin F belongs to cystatin superfamily, which encompasses proteins that contain multiple cystatin-like sequences. It has been shown that Cystatin F is selectively expressed by hematopoietic cells and may be a biomarker for both liver metastasis and inflammatory lung disorders. Mouse Cystatin F inhibits papain and cathepsin L but with affinities lower than other cystatins. It may play a role in immune regulation through inhibition of a unique target in the hematopoietic system. |
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TMPJ-00324
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ICAM-1/CD54 Protein, Rhesus macaque, Recombinant (hFc)
Intercellular adhesion mol
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Rhesus
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HEK293 Cells
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Intercellular adhesion molecule 1 (ICAM1) is known as CD54. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. The endothelial expression of ICAM-1 is increased in atherosclerotic and transplant-associated atherosclerotic tissue and animal models of atherosclerosis. Additionally, ICAM-1 has been implicated in the progression of autoimmune diseases. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-... |
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TMPJ-00253
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OPG Protein, Mouse, Recombinant (His)
Opg,Ocif,Tnfrsf11b,Osteoclastogenesis inhibitory fa...
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Mouse
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HEK293 Cells
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Osteoprotegerin (OPG, Tnfrsf11b) is a secreted protein that regulates bone density. OPG is widely expressed and constitutively released as a homodimer by mesenchymal stem cells, fibroblasts and endothelial cells. Regulation of its expression by estrogen, parathyroid hormone and cytokines is complex and changes with age. OPG acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. TRAIL decreases the release of OPG from cells that express it, while OPG ... |
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TMPJ-00524
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SORD Protein, Human, Recombinant (His)
Sorbitol Dehydrogenase,L-Iditol 2...
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Human
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HEK293 Cells
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Sorbitol dehydrogenase, also known as L-iditol 2-dehydrogenase and SORD, is a member of the zinc-containing alcohol dehydrogenase family. SORD exsits in a homotetramer and binds one zinc ion per subunit. SORD is expressed in kidney and epithelial cells of both benign and malignant prostate tissue. SORD can converts sorbitol to fructose and catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase to make up the sorbitol pathway. SORD is up-regul... |
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TMPY-01249
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Cathepsin V Protein, Human, Recombinant (His)
CTSV,cathepsin V,MGC125957,CATL2,CTSU,CTSL...
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Human
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HEK293 Cells
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Cathepsin V (CTSV), also known as Cathepsin L2, CTSL2, and CATL2, is a member of the peptidase C1 family. It is predominantly expressed in the thymus and testis. Cathepsin V is also expressed in corneal epithelium, and to a lesser extent in conjuctival epithelium and skin. It is a lysosomal cysteine proteinase that may play an important role in corneal physiology. It has about 75% protein sequence identity to murine cathepsin L. The fold of this enzyme is similar to the fold adopted by other mem... |
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TMPJ-00257
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PSGL-1/CD162 Protein, Human, Recombinant (hFc)
Selectin P ligand,P-selectin g
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Human
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HEK293 Cells
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PSGL-1 (CD162), is a mucintype glycoprotein that plays a key role in leukocyte adhesion. Human PSGL-1 cDNA encodes 412 amino acids (aa). It expressed on neutrophils, monocytes and most lymphocytes. The mature PSGL-1 (aa 42-412) is expressed as a disulfide-linked homodimer that signals intracellularly and promotes integrin activation. PSGL-1 is found on virtually all leukocytes, dendritic cells, platelets, and some endothelial cells. It is primarily responsible for early events in extravasation, ... |
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TMPY-02766
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PSPH Protein, Human, Recombinant
PSP,phosphoserine phosphatase,PSPHD
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Human
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E. coli
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Phosphoserine phosphatase (PSPH) belongs to a subfamily of the phosphotransferases. PSPH is the rate-limiting enzyme in l-serine biosynthesis. It has previously been found that Phosphoserine phosphatase (PSPH) plays a role in epidermal homeostasis. Phosphoserine phosphatase (PSP) catalyzes the hydrolysis of phosphoserine to serine. Phosphoserine phosphatase (PSPH) expression has been examined in human-mouse somatic cell hybrids retaining different combination of human chromosomes. Phosphoserine ... |
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TMPJ-01142
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CDO1 Protein, Human, Recombinant (His)
CDO-I,CDO,Cysteine Dioxygenase Type I,CDO1,Cysteine Dioxygen...
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Human
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E. coli
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Cysteine Dioxygenase Type 1 (CDO1) is a mammalian non-heme iron enzyme that belongs to the cysteine dioxygenase family. CDO1 is highly expressed in the liver and placenta, and has a low expression in heart, brain and pancreas. CDO1 can also be detected in hepatoblastoma HepG2 cells. CDO1 catalyzes the conversion of L-cysteine to cysteine sulfinic acid by incorporation of dioxygen. CDO1 is a vital regulator of cellular cysteine concentrations and has an essential role in maintaining the hepatic c... |
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TMPY-02724
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XCL2 Protein, Human, Recombinant (His)
SCM1B,hCG_1729916,SCM-1b,chemokine (C motif) ligand...
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Human
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Baculovirus Insect Cells
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XCL2 is a small cytokine belonging to the XC chemokine family. Chemokines are a group of cytokines. Members of this group of so-called C-Chemokines belong to the SCY family of cytokines and are designated XCL (L for ligand) followed by a number. XCL2 is the new designation of SCM-1-beta. XCL2 is highly related to another chemokine called XCL1. XCL2 gene is located on chromosome 1 in humans. XCL2 is predominantly expressed in activated T cells, but can also be found at low levels in unstimulated ... |
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TMPH-00775
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IFN gamma Protein, Goat, Recombinant (His & Myc)
Interferon gamma,IFNG
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Goat
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E. coli
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Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation. Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation. Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activati... |
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TMPH-02526
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Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO)
Arginase II,Kidney-type arginase,Type II arginase,Arg2,Argin...
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Mouse
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E. coli
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May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS). Arginine metabolism is a critical regulator of innate and adaptive immune responses. Seems to be involved in negative regulation of the survival capacity of activated CD4(+) and CD8(+) T cells. May suppress inflammation-related signaling in asthmatic airway epithelium.... |
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TMPY-02642
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UBE2W Protein, Human, Recombinant (His)
UBC16,UBC-16,ubiquitin-conjugating enzyme E2W (putative)
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Human
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E. coli
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Ubiquitin-conjugating enzymes, also known as UBE2W, E2 enzymes and more rarely as ubiquitin-carrier enzymes, perform the second step of protein ubiquitination. The modification of protein with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2W is a member of th... |
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TMPY-01268
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SMYD3 Protein, Human, Recombinant (GST)
SET and MYND domain containing 3,ZMYND1,KMT3E,ZNFN3A1,bA74P1...
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Human
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Baculovirus Insect Cells
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SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger and one SET domain. SMYD3 is a histone H3 lysine-4-specific methyltransferase. It is expressed in skeletal muscles and testis. It is overexpressed in a majority of colorectal carcinoma (CRC) and hepatocellular carcinoma (HCC). SMYD3 plays an important role in transcriptional reg... |
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TMPY-03465
|
Flagellin Protein, Listeria monocytogenes, Recombinant (His)
flaA
|
Listeria monocytogenes
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E. coli
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The role of flagella and motility in the attachment of the foodborne pathogen Listeria monocytogenes to various surfaces is mixed with some systems requiring flagella for an interaction and others needing only motility for cells to get to the surface. In nature this bacterium is a saprophyte and contaminated produce is an avenue for infection. Previous studies have documented the ability of this organism to attach to and colonize plant tissue. Motility mutants were generated in three wild ... |
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