644
134
5
168
12
Cat. No. | Product Name | ||
---|---|---|---|
L1600 | 激酶抑制剂库 | 2720 compounds | |
2720 种激酶抑制剂/调节剂的独特集合,用于特定靶向激酶,可用于高通量筛选和高内涵筛选; | |||
L2200 | 酪氨酸激酶分子库 | 1016 compounds | |
1016 种酪氨酸激酶抑制剂的独特集合,可用于高通量筛选和高内涵筛选; | |||
L1610 | FDA 上市激酶抑制剂库 | 263 compounds | |
263种靶向激酶的上市药物集合,用于特定靶向激酶,可用于高通量筛选和高内涵筛选; | |||
L1720 | 核苷类化合物库 | 334 compounds | |
334 种核苷类化合物,包括核苷酸、核苷酸类似物及衍生物等,适用于抗病毒、抗肿瘤、抗真菌、抗抑郁等药物的研发; | |||
L3510 | 甲基化化合物库 | 128 compounds | |
128 种甲基化相关的化合物,可以用于高通量和高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T16364 |
Infigratinib phosphate
NVP-BGJ398 phosphate,BGJ-398 phosphate |
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
Infigratinib phosphate (BGJ-398 phosphate) 是 FGFR 抑制剂,对 FGFR1,FGFR2 和 FGFR3 的 IC50 分别为0.9,1.4 和 1 nM,比对 FGFR4 和 VEGFR2 的抑制性高40倍,对 Abl,Fyn,Kit,Lck 和 Lyn 几乎无活性。 | |||
T12477 |
Uzansertib phosphate
INCB053914 phosphate |
Pim | Chromatin/Epigenetic; JAK/STAT signaling |
Uzansertib phosphate (INCB053914 phosphate) 是一种可口服的 ATP 竞争性泛-PIM 激酶抑制剂,对多种血液肿瘤细胞系具有广泛的抗增殖活性,对 PIM1、PIM2 和 PIM3 的 IC50分别为 0.24 、30 和 0.12 nM。 | |||
T3043 |
Ruxolitinib phosphate
INC424,INCB018424,INC 424 phosphate,Ruxolitinib (INCB-18424) phosphate,INCB018424 phosphate,磷酸鲁索利替尼 |
Mitophagy; JAK; Autophagy | Angiogenesis; Autophagy; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells |
Ruxolitinib phosphate (INCB018424) 是一种 JAK1/2抑制剂,IC50分别为3.3 nM/2.8 nM,对 JAK1/2 的选择性是 JAK3 的 130 倍以上。 | |||
T2360 |
Baricitinib phosphate
Baricitinib Phosphate,LY3009104,磷酸巴瑞克替尼,INCB-028050 phosphate,LY-3009104 phosphate,INCB028050 |
Tyrosine Kinases; JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors |
Baricitinib phosphate (INCB028050) 是一种选择性的,可口服的 JAK1/JAK2抑制剂,IC50值分别为 5.9 和 5.7 nM。 | |||
T23358 |
Sitagliptin phosphate
磷酸西他列汀,Januvia,MK-0431 phosphate,Sitagliptin (phosphate) |
DPP-4; Autophagy | Autophagy; Proteases/Proteasome |
Sitagliptin phosphate (MK-0431 phosphate) 是一种二肽基肽酶 4 (DPP4) 抑制剂,在 Caco-2 细胞中,IC50值为 19 nM。 | |||
T0821 |
Iproniazid Phosphate
磷酸异丙烟肼,Isoproniazid phosphate |
MAO; Monoamine Oxidase | Metabolism; Neuroscience |
Iproniazid Phosphate 是一种非选择性的,不可逆的单胺氧化酶抑制剂,具有抗抑郁作用。 | |||
T27400L |
Ganaplacide phosphate
Ganaplacide phosphate (1261113-96-5 Free base) |
Others | Others |
Ganaplacide phosphate 对疟原虫症状性无性血期感染具有多阶段抗疟活性,并且能够在动物模型中预防传播和阻断感染。 | |||
T7394 |
Toceranib Phosphate
SU11654 phosphate,PHA 291639 phosphate,托西尼布磷酸盐 |
VEGFR; Tyrosinase; PDGFR; c-Kit | Angiogenesis; Proteases/Proteasome; Tyrosine Kinase/Adaptors |
Toceranib Phosphate (SU11654 phosphate) 是有效的、具有口服活性的酪氨酸激酶 (RTK) 受体抑制剂,能抑制PDGFR,VEGFR,Kit,抑制 PDGFRβ 和 Flk-1/KDR 的Ki 分别为 5 nM 和 6 nM。它具有抗肿瘤和抗血管生成作用,可用于研究犬肥大细胞肿瘤。 | |||
T1348 |
Diphenyl phosphate
磷酸二苯酯,Phenyl hydrogen phosphate |
Others | Others |
Diphenyl Phosphate 能够性别特异性的抑制斑马鱼的生长和能量代谢。 | |||
T21244 |
NSI-189 Phosphate
NSI189 Phosphate,NSI 189 Phosphate,NSI-189磷酸盐 |
Others | Others |
NSI-189 Phosphate 是一种新型神经源性分子,具有多效性,包括临床前研究中证明的抗抑郁、促认知、突触和神经营养活性。其抗抑郁活性不依赖于单胺。 | |||
T68132L |
Quercetin-3'-o-phosphate TEA
Quercetin-3'-o-phosphate TEA(1111616-69-3 Free base),3'-quercetin phosphate TEA,Quercetin 3'-phosphate TEA |
Adenosine Receptor | GPCR/G Protein; Neuroscience |
Quercetin-3'-o-phosphate TEA (Quercetin 3'-phosphate TEA)是一种腺苷 A 受体拮抗剂,可用来预防和治疗代谢紊乱。 | |||
T1142 |
Clindamycin phosphate
Clindamycin 2-phosphate,Clindamycin 2-dihydrogen phosphate,NSC 618653,U-28508,克林霉素磷酸酯 |
ribosome; Antibacterial; Antibiotic; Parasite | Microbiology/Virology |
Clindamycin phosphate (Clindamycin 2-dihydrogen phosphate) 是一种抗生素,抑制微生物的核糖体作用。可研究厌氧菌感染和原虫疾病。 | |||
T67689 |
Sodium 4-nitrophenyl phosphate hexahydrate
4-Nitrophenyl phosphate disodium hexahydrate,p-Nitrophenyl phosphate disodium hexahydrate |
Others | Others |
Sodium 4-nitrophenyl phosphate hexahydrate (4-Nitrophenyl phosphate disodium hexahydrate) 可被酒精磷酸酶(ALP)水解, 可用于开发检测赭曲霉毒素 A (OTA) 的双模式免疫测定法。 | |||
T6501 |
Fludarabine Phosphate
NSC 312887 Phosphate,fludara Phosphate,F-ara-A (NSC 312887) Phosphate,F-ara-AMP,磷酸氟达拉滨 |
Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis | Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Fludarabine Phosphate (NSC 312887 Phosphate) 是一种腺苷和脱氧腺苷类似物,与 dATP 竞争,并入到 DNA,可以抑制 DNA 聚合酶 α、核糖核苷酸还原酶和 DNA 引发酶,从而中断 DNA 合成并抑制肿瘤细胞生长。 | |||
T6127 |
Rucaparib Phosphate
AG-014699 phosphate,PF-01367338,芦卡帕利,AG-014699,瑞卡帕布磷酸盐,PF-01367338 phosphate |
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
Rucaparib Phosphate (PF-01367338 phosphate) 是一种口服有效的PARP 蛋白抑制剂,对 PARP-1 的Ki 为 1.4 nM。它是六磷酸己糖脱氢酶 (H6PD) 抑制剂,有用于去势抵抗性前列腺癌 (CRPC) 的研究潜力。 | |||
T8127 |
Disodium Phosphate
Sodium hydrogen phosphate,Sodium phosphate dibasic,磷酸氢二钠,Disodium hydrogen orthophosphate |
Others | Others |
Disodium Phosphate (Sodium hydrogen phosphate) 通常用作食品添加剂,它还具有腐蚀抑制剂的作用。 | |||
T0342 |
Carvedilol phosphate hemihydrate
Carvedilol phosphate,BM 14190 (phosphate hemihydrate),卡维地洛磷酸盐 |
VEGFR; Others; Potassium Channel; LDL; Integrin; Gap Junction Protein; NADPH; Adrenergic Receptor; Autophagy | Angiogenesis; Autophagy; Cytoskeletal Signaling; GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Neuroscience; Others; Tyrosine Kinase/Adaptors |
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) 是一种外消旋混合物,是一种非选择性β/α-1受体阻断剂,具有抗高血压活性且缺乏内在拟交感神经活性。 | |||
T63918 |
α-Tocopherol phosphate disodium
TocP disodium,Vitamin E phosphate disodium |
Apoptosis; Antioxidant; Reactive Oxygen Species | Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction |
α-Tocopherol phosphate (alpha-Tocopherol phosphate) 是一种抗氧化剂,能够清除 UVA1 诱导的活性氧 (ROS) 并保护长波 UVA1 诱导的细胞死亡。α-Tocopherol phosphate disodium (Vitamin E phosphate disodium) 可阻碍内皮祖细胞凋亡 (apoptosis),增强高糖/低氧条件下内皮祖细胞迁移能力,促进血管生成。 | |||
T5007 |
Benproperine phosphate
磷酸苯丙哌林,Blascorid,Pirexyl phosphate |
Others; Microtubule Associated | Cytoskeletal Signaling; Others |
Benproperine phosphate (Pirexyl phosphate) 是一种具有口服活性的,肌动蛋白相关蛋白 2/3 复合亚基 2 (ARPC2) 抑制剂。它通过削弱 Arp2/3 功能来减弱肌动蛋白的聚合反应速率。它可抑制癌细胞迁移和肿瘤转移,有用于治疗止咳的潜力。 | |||
T6998 |
Tedizolid Phosphate
TR-701FA,Torezolid phosphate,磷酸特地唑胺 |
Antibacterial; Antibiotic | Microbiology/Virology |
Tedizolid Phosphate (TR-701FA) 是 MAO-A 和 MAO-B 抑制剂,具有抗革兰氏阳性菌的活性。 | |||
T0208 |
Prednisolone disodium phosphate
泼尼松龙21-磷酸二钠,Prednisolone phosphate sodium,Prednisolone 21-phosphate disodium,泼尼松龙磷酸钠 |
Glucocorticoid Receptor | Endocrinology/Hormones |
Prednisolone disodium phosphate是一种合成的糖皮质素,具有抗炎和免疫调节作用。 | |||
T4451 |
Estramustine phosphate sodium
Ro 21-8837/001,Estramustine phosphate disodium,雌莫司汀磷酸钠 |
Apoptosis; Microtubule Associated | Apoptosis; Cytoskeletal Signaling |
Estramustine phosphate sodium (Ro 21-8837/001) 是雌二醇类似物,是一种具有口服活性抗微管化疗剂,通过与微管相关蛋白和微管蛋白结合而使微管解聚。它可诱导前列腺癌细胞凋亡,可研究前列腺癌。 | |||
T0242L |
Sitagliptin phosphate monohydrate
MK-0431,MK-0431 phosphate monohydrate,西他列汀磷酸盐一水合物 |
Proteasome; DPP-4; Autophagy | Autophagy; Proteases/Proteasome; Ubiquitination |
Sitagliptin phosphate monohydrate (MK-0431 phosphate monohydrate) 是一种有效的 DPP-IV 抑制剂,在 Caco-2 细胞提取物中的 IC50 为 19 nM。 | |||
T20763 |
Betamethasone disodium phosphate
Vista-Methasone,NSC90616,Betamethasone 21-phosphate disodium salt,NSC-90616 |
Others | Others |
Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt) 是一种具有抗炎活性的皮质类固醇,通过减少促炎细胞因子的分泌促进 M1 至 M2 巨噬细胞极化,可用于研究瘢痕疙瘩和类风湿性关节炎。 | |||
T12174 |
Naphthoquine phosphate
|
Parasite | Microbiology/Virology |
Naphthoquine phosphate 是一种具有口服活性的广谱4-氨基喹啉类抗疟化合物,可能影响病毒进入和进入后复制。Naphthoquine phosphate 具有肝血管中心毒性,常与青蒿素一起使用来治疗疟疾。 | |||
T2606 |
KN-93 Phosphate
|
CaMK | Neuroscience |
KN-93可以竞争性阻断钙调蛋白与对应激酶的结合,是一种钙离子/钙调蛋白依赖激酶 II(CaMKII)抑制剂,Ki 为370 nM。 | |||
T39113L |
Povorcitinib phosphate
|
JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells |
Povorcitinib phosphate 是一种选择性 JAK1 抑制剂,可用于治疗皮肤红斑狼疮和扁平苔藓的研究。 | |||
T37985 |
D-Fructose-6-phosphate (sodium salt hydrate)
D-Fructose-6-phosphate (sodium salt hydrate) (643-13-0 free base) |
||
D-Fructose-6-phosphate (sodium salt hydrate) 是由磷酸葡萄糖异构酶将 6-磷酸葡萄糖异构化产生的糖酵解途径的糖中间体,可用于研究癌症。 | |||
T1486 |
Oseltamivir phosphate
GS 4104,磷酸奥司他韦 |
Influenza Virus | Microbiology/Virology |
Oseltamivir phosphate (GS 4104) 是一种神经氨酸酶抑制剂,可研究流感。 | |||
T20048 |
Vidarabine phosphate
|
Antiviral | Immunology/Inflammation |
Vidarabine phosphate 是一种单磷酸腺苷类似物。它是 VIDARABINE 的单磷酸酯。它还具有抗病毒和可能的抗肿瘤特性。 | |||
T23175 |
Potassium phosphate monobasic
|
Others | Others |
Potassium phosphate monobasic 是生物测定时常用的缓冲液。它是中等浓度至高浓度的磷酸二氢钾水溶液,可用于制备磷酸盐缓冲液以及其他实验试剂。 | |||
T5027 |
Dimemorfan phosphate
二甲啡烷磷酸盐,3,17-dimethylmorphinan |
Sigma receptor | GPCR/G Protein |
Dimemorfan phosphate (3,17-dimethylmorphinan) 是 sigma 1 受体激动剂,用作强效镇咳药。 | |||
T6641 |
Rilmenidine Phosphate
|
Apoptosis; Adrenergic Receptor; Autophagy; Imidazoline Receptor | Apoptosis; Autophagy; GPCR/G Protein; Neuroscience |
Rilmenidine phosphate 是一种新型的抗高血压药物和口服活性选择性 I1 咪唑啉受体激动剂。它可调节白血病细胞增殖,刺激促凋亡蛋白 Bax,从而诱导人白血病 K562 细胞线粒体通路的紊乱和凋亡。它可通过减少交感神经过度活跃而发挥中枢作用,并通过抑制 Na+/H+反向转运而在肾脏中发挥作用。 | |||
T6465 |
Dexamethasone Sodium Phosphate
Dexadreson,地塞米松磷酸钠,Dexagro,Dalalone |
IL Receptor; COX | Immunology/Inflammation; Neuroscience |
Dexamethasone Sodium Phosphate (Dexadreson) 是一种白细胞介素受体调节剂,具有抗炎和免疫抑制作用。它属于类固醇合成药物的强效糖皮质激素类。 | |||
T4530 |
KN-92 phosphate
KN-92 磷酸盐,KN92-H3PO4 |
CaMK | Neuroscience |
KN-92 phosphate (KN92-H3PO4) 是 KN-93 的非活性衍生物,不能抑制 CaM 激酶活性。它可作为阐明 KN-93 的拮抗活性的对照化合物。KN-93 能够渗透细胞,是一种可逆的 CaMKII 竞争性抑制剂。 | |||
T19699 |
Triciribine phosphate
TCN-P,VD 002,VQD-002 |
Apoptosis; Akt | Apoptosis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling |
Triciribine phosphate (VD 002) 是一种高选择性的 AKT 抑制剂,可诱导细胞周期停滞和半胱天冬酶依赖性细胞凋亡,抑制新生血管的生成,可用于研究白血病。 | |||
T12710 |
Retagliptin Phosphate
SP 2086,瑞格列汀磷酸盐 |
Proteasome; DPP-4 | Proteases/Proteasome; Ubiquitination |
Retagliptin Phosphate (SP 2086) 是一种选择性、竞争性、口服活性的二肽基肽酶 4 (DPP-4) 抑制剂。Retagliptin phosphate 能够用于 2 型糖尿病 (T2DM) 的研究。 | |||
T22439 |
Tilmicosin phosphate
磷酸替米考星,替米考星磷酸盐 |
Antibacterial; Antibiotic | Microbiology/Virology |
Tilmicosin phosphate 是一种抗生素,可研究曼氏杆菌和巴氏杆菌相关的牛羊呼吸系统疾病。 | |||
T22215 |
1-Naphthyl phosphate potassium salt
|
Phosphatase | Metabolism |
1-Naphthyl phosphate potassium salt 是非特异性磷酸酶 (phosphatase) 抑制剂,能够降低剪接校正作用。 | |||
T0947L |
Dexamethasone Phosphate disodium
地塞米松磷酸二钠,EGP-437,EGP437. Dex-Phos,EGP 437 |
Glucocorticoid Receptor | Endocrinology/Hormones |
Dexamethasone Phosphate disodium (EGP437. Dex-Phos) 是糖皮质激素受体激动剂。 | |||
T18888 |
4-Methylumbelliferyl phosphate
4-甲基伞形酮磷酸酯,4-MUP |
Others | Others |
4-Methylumbelliferyl phosphate (4-MUP) 是碱性磷酸酶的荧光底物。 | |||
T37986 |
D-Mannose-6-Phosphate sodium salt hydrate
|
Others | Others |
D-Mannose-6-Phosphate sodium salt hydrate 是一种多功能单糖,可用于研究代谢、溶酶体传递和癌症。 | |||
T11013L2 |
Levorotation nimorazole phosphate ester TFA
|
Others | Others |
Levorotation nimorazole phosphate ester TFA 是一种抗厌氧菌和抗原虫感染的试剂。 | |||
T0653 |
Tris(2-chloroethyl) phosphate
Disflamoll TCA,Fyrol CEF,磷酸三氯乙酯,Celluflex |
Others | Others |
Tris(2-chloroethyl) phosphate (Fyrol CEF) 用作阻燃剂。 | |||
T35382 |
Potassium phosphate dibasic
Dipotassium phosphate |
Others | Others |
Potassium phosphate dibasic (Dipotassium phosphate, K2HPO4)常被用作肥料、食品添加剂和缓冲剂。 | |||
T40930 |
(S)-Sitagliptin phosphate
(S)-Sitagliptin phosphate,(S)-MK-0431 phosphate |
Others | Others |
(S)-Sitagliptin phosphate, the less active S-enantiomer of Sitagliptin phosphate, is a high-potency inhibitor of DPP4. It exhibits an IC50 of 19 nM in Caco-2 cell extracts. | |||
T11013L1 |
Dextrorotation nimorazole phosphate ester TFA
|
Others | Others |
Dextrorotation nimorazole phosphate ester TFA 是一种抗厌氧菌和抗原虫感染的试剂。 | |||
T39401 |
Sphinganine 1-phosphate
D-erythro-Dihydrosphingosine 1-phosphate,Sphinganine 1-phosphate |
Others | Others |
Sphinganine 1-phosphate, also known as D-erythro-Dihydrosphingosine 1-phosphate, is a polar sphingolipid metabolite. It plays a crucial role in regulating various cellular processes including cell migration, differentiation, survival, and complex physiological processes. | |||
T28272 |
Osilodrostat phosphate
LCI699 phosphate,LCI 699 phosphate,LCI-699 phosphate |
Others | Others |
Osilodrostat phosphate is a potent oral 11β-hydroxylase inhibitor. | |||
T12792 |
S-8510 phosphate
SB-737552 phosphate |
Others | Others |
S-8510 phosphate is an agonist of inverse Benzodiazepine (BDZ) receptor(Kis of 34.6 nM, 36.2 nM for –GABA and +GABA respectively). |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T14149 |
AICAR phosphate
AICA Riboside phosphate,Acadesine phosphate |
Mitophagy; NOS; YAP; AMPK | Autophagy; Chromatin/Epigenetic; Immunology/Inflammation; PI3K/Akt/mTOR signaling; Stem Cells |
AICAR phosphate (Acadesine phosphate) 是 AMPK 激活剂且是自噬、YAP 和 mitophagy 抑制剂,也是一种腺苷类似物, 可调节糖代谢和脂代谢,抑制促炎细胞因子和 iNOS 的产生。 | |||
T3578 |
Pyridoxal phosphate
PLP,PAL-P,磷酸吡哆醛,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate |
Reverse Transcriptase; Endogenous Metabolite | Metabolism; Microbiology/Virology |
Pyridoxal phosphate (Vitamin B6 phosphate) 是维生素 B6 的活性形式,可抑制逆转录酶活性,用于研究迟发性运动障碍症。 | |||
T0194 |
Chloroquine phosphate
Chloroquine diphosphate,Aralen phosphate,磷酸氯喹,Chingamin phosphate |
SARS-CoV; TLR; HIV Protease; Antibiotic; Parasite; Autophagy | Autophagy; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome |
Chloroquine phosphate (Aralen phosphate) 是广泛用于疟疾和类风湿性关节炎的抗疟疾和抗炎剂。它是autophagy 和toll-like receptors 抑制剂,有效抑制SARS-CoV-2(COVID-19) 感染 (EC50=1.13 μM)。 | |||
T6535 |
Histamine Phosphate
组胺磷酸盐,Histamine diphosphate,二磷酸组胺,Histamine acid phosphate |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Histamine Phosphate (Histamine acid phosphate) 是组胺受体的强激活剂和血管扩张神经剂,可激活一氧化氮合成酶。 | |||
T8083 |
Pyridoxal 5'-phosphate monohydrate
Pyridoxal phosphate monohydrate,Pyridoxal 5-phosphate monohydrate,5-磷酸吡哆醛 |
Others | Others |
Pyridoxal 5-phosphate monohydrate 是维生素B6的活性形式,也是多种酶的重要辅因子。它是维生素 B6 在细胞内磷酸化过程中最重要的辅酶变异体,能够与其他变异体(如 PNP 、 PMP)发生互换。 | |||
T1331 |
Riboflavin phosphate sodium
Riboflavin 5'-phosphate sodium,核黄素磷酸钠(维生素B2),Vitamin B2 Phosphate Sodium Salt,Flavin mononucleotide,FMN,核黄素磷酸钠,FMN-Na,riboflavin-5'-phosphate |
Endogenous Metabolite | Metabolism |
Riboflavin phosphate sodium (FMN) 是 riboflavin 的磷酸钠盐形式,riboflavin 是一种水溶性和必需的微量营养素,是自然产生的维生素B复合物的主要生长促进因子。Riboflavin phosphate sodium 转化为2种辅酶,黄素单核苷酸(FMN)和黄素腺嘌呤二核苷酸(FAD),这两种辅酶通过帮助脂肪、碳水化合物和蛋白质的代谢来产生能量,并且是红细胞形成和呼吸、抗体产生以及调节人体生长和繁殖所必需的。 | |||
T7989 |
Trimethyl phosphate
|
Others | Others |
Trimethyl phosphate 是一种有机磷化合物,是催化磷酸化化合物水解的酶的抑制剂,已被用作合成肽和其他蛋白质的反应物,用作合成有机和无机化合物的催化剂,以及用作合成药物的试剂。 | |||
T19281L |
Dihydroxyacetone phosphate hemimagnesium hydrate
DHAP Mg,Dihydroxyacetone phosphate hemimagnesium salt hydrate(57-04-5 free base) |
Others | Others |
Dihydroxyacetone phosphate hemimagnesium salt hydrate 也称为磷酸二羟基丙酮或 3-羟基-2-氧代丙基磷酸。 Dihydroxyacetone phosphate hemimagnesium salt hydrate 存在于从细菌到人类的所有生物中。在人类体内, Dihydroxyacetone phosphate hemimagnesium salt hydrate参与许多酶促反应。 Dihydroxyacetone phosphate hemimagnesium salt hydrate 已被研究用于治疗淋巴瘤、大细胞淋巴瘤、弥漫性淋巴瘤。 | |||
T4739 |
Sodium creatine phosphate dibasic tetrahydrate
磷酸肌酸二钠盐,Creatine phosphate disodium salt tetrahydrate |
Others; Endogenous Metabolite | Metabolism; Others |
Sodium creatine phosphate dibasic tetrahydrate (Creatine phosphate disodium salt tetrahydrate) 主要存在于脊椎动物的骨骼肌中,是测定肌酸激酶的底物,能够用于骨骼肌收缩过程中 ATP 的再生。 | |||
T5213 |
Acetyl phosphate(lithium potassium)
乙酰磷酸锂钾盐,Lithium potassium acetyl phosphate,Acetylphosphoric acid |
Others; Endogenous Metabolite | Metabolism; Others |
Acetyl phosphate lithium potassium (Lithium potassium acetyl phosphate) 是内源性代谢产物的一种。 | |||
T5085 |
Pyridoxal 5'-phosphate hydrate
Codecarboxylase,Pyridoxal 5'-phosphate hydrate(1:x),5-磷酸吡多醛水合物,PLP,Pyridoxal 5'-phosphate hydrate |
Others; Endogenous Metabolite | Metabolism; Others |
Pyridoxal 5'-phosphate hydrate (PLP) 是内源性代谢产物的一种。 | |||
T19262 |
D-Glucose 6-phosphate disodium salt
D-Glucose 6-phosphate disodium salt |
Endogenous Metabolite | Metabolism |
D-Glucose 6-phosphate disodium salt 广泛存在于生物提内的化合物,是葡萄糖第 6 号碳经过磷酸化后生成的分子,参与磷酸戊糖途径与糖酵解途径等体内多种多种代谢调节途径。 | |||
T4924 |
α-D-Glucose-1-phosphate disodium
A-D-葡萄糖-1-磷酸-二钠盐,α-D-Glucose 1-phosphate disodium salt hy,α-D-Glucopyranose 1-phosphate |
Others; Endogenous Metabolite | Metabolism; Others |
α-D-Glucose 1-phosphate disodium salt hydrate 是合成葡萄糖醛酸的起始原料。它可用作心脏病研究所必需的细胞抑制剂、抗生素、免疫抑制剂和循环系统研究材料。 | |||
T4942 |
Galactose 1-phosphate Potassium salt
D-半乳糖 1-磷酸二钾盐五水合物,α-D-Galactose-1-phosphate Dipotassium Pentahydrate |
Others; Endogenous Metabolite | Metabolism; Others |
Galactose 1-phosphate Potassium salt (α-D-Galactose-1-phosphate Dipotassium Pentahydrate) 是一种半乳糖代谢中的中间体和核苷酸糖。 | |||
T4726 |
D-Glucose 6-phosphate sodium
G6P sodium salt,D-Glucose 6-phosphate sodium salt,D-葡萄糖-6-磷酸钠盐,Sodium Glucose-6-Phosphate |
Others; Endogenous Metabolite | Metabolism; Others |
D-Glucose 6-phosphate sodium (G6P sodium salt) 是内源性代谢产物的一种。 | |||
T4941 |
D-Fructose-6-phosphate disodium salt
D-FRUCTOSE 6-PHOSPHATE DISODIUM SALT,D-果糖-6-磷酸二钠 |
Others; Endogenous Metabolite | Metabolism; Others |
D-Fructose-6-phosphate disodium salt (D-FRUCTOSE 6-PHOSPHATE DISODIUM SALT) 是内源性代谢产物的一种。 | |||
T7192 |
Diethyl phosphate
Diethyl phosphoric acid,磷酸二乙酯 |
Others; Endogenous Metabolite | Metabolism; Others |
Diethyl phosphate (Diethyl phosphoric acid) 是一种常用杀虫剂Chlorpyrifos 的代谢或天然降解产物。 | |||
T2185 |
L-Ascorbic acid 2-phosphate trisodium
L-抗坏血酸-2-磷酸三钠盐(维生素C),L-Ascorbic acid 2-phosphate trisodium salt,Sodium L-ascorbyl-2-phosphate,Sodium ascorbyl phosphate,2-Phospho-L-ascorbic acid trisodium salt,Sodium ascorbyl monophosphate,L-抗坏血酸-2-磷酸三钠盐 |
Reactive Oxygen Species; c-Met/HGFR; Endogenous Metabolite | Immunology/Inflammation; Metabolism; NF-κB; Tyrosine Kinase/Adaptors |
L-Ascorbic acid 2-phosphate trisodium (Sodium ascorbyl phosphate) 是长效的维生素 C 衍生物,能够刺激胶原蛋白的表达和形成。Sodium L-ascorbyl-2-phosphate 提高成骨细胞分化过程中 hASC 中的碱性磷酸酶活性和 runx2A 的表达,因此,能够促进人脂肪干细胞的成骨分化。 | |||
T5069 |
D-Glucose 6-phosphate potassium salt
|
Others | Others |
在细胞中,当葡萄糖被己糖激酶或葡萄糖激酶磷酸化或在糖原分解过程中通过磷酸葡萄糖变位酶转化葡萄糖 1-磷酸时,会产生D-glucose 6-phosphate (G6P)。 G6P 位于糖酵解和戊糖磷酸途径的起点。当血糖水平高时,它也可以作为糖原储存。 | |||
T19343L |
Glycerol 3-phosphate biscyclohexylammonium salt
|
Endogenous Metabolite | Metabolism |
Glycerol 3-phosphate biscyclohexylammonium salt 是胞质甘油 3-磷酸脱氢酶途径中产生的,即利用 NADH 还原二羟丙酮磷酸的过程。 | |||
T13206 |
Tris(2,4-di-tert-butylphenyl)phosphate
|
Phospholipase | Metabolism |
Tris(2,4-di-tert-butylphenyl)phosphate 是一种从 Vitex negundoL 中分离的活性化合物,能够通过分子对接抑制了分泌性磷脂酶 A2(sPLA2),具有抗炎作用。 | |||
T13870 |
Riboflavine phosphate
Riboflavine 5'-phosphate |
Endogenous Metabolite | Metabolism |
Riboflavine phosphate (Flavin mononucleotide)是 Riboflavin 的衍生物。Riboflavin phosphate 可用于研究圆锥角膜、角膜扩张、不规则散光。Riboflavine phosphate 是一种高效经济的 NAD+ 回收剂。 | |||
T10005L |
1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium
|
Endogenous Metabolite | Metabolism |
1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium 是一种人内源性代谢物,是一种磷酸酯。 | |||
T78485 |
D-Glucosamine 6-phosphate
Glucosamine-6-phosphate |
Endogenous Metabolite | Metabolism |
D-Glucosamine 6-phosphate为内源性代谢分子,谷氨酰胺果糖-6-磷酸氨基转移酶(GFAT)介导合成。该化合物常用于糖尿病研究领域。 | |||
T6272 |
Fosbretabulin Disodium
Combretastatin A4 Phosphate,CA 4DP,CA 4P,福他布林,Combretastatin A4 disodium phosphate,Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium |
Apoptosis; Microtubule Associated | Apoptosis; Cytoskeletal Signaling |
Fosbretabulin Disodium (CA 4P) 是一种微管蛋白去稳定剂,是 Combretastatin A4 前药,可选择性靶向内皮细胞,诱导新生肿瘤新血管消退,减少肿瘤血流量并引起中央肿瘤坏死。 | |||
T19343 |
sn-Glycerol 3-phosphate
Glycerol 3-phosphate,SN-甘油3-磷酸 锂盐,sn-Glycerol 3-phosphate lithium salt |
Endogenous Metabolite | Metabolism |
sn-Glycerol 3-phosphate 是一种人内源性化合物,由NADH 还原磷酸二羟基丙酮而产生。 | |||
T19281 |
Dihydroxyacetone phosphate
|
Others | Others |
Dihydroxyacetone phosphate is an important intermediate for lipid biosynthesis and glycolysis. It is a biochemical compound involved in many metabolic pathways, including the Calvin cycle and glycolysis in plants. It was found that dihydroxyacetone phosph | |||
T21500 |
Sphingosine-1-phosphate
S1P |
Endogenous Metabolite; S1P Receptor; LPL Receptor | GPCR/G Protein; Metabolism |
Sphingosine-1-phosphate (S1P) 是 S1P1-5 受体 (S1P1-5 receptors) 的激动剂和 GPR3、GPR6、GPR12 的配体。Sphingosine-1-phosphate 是细胞内的第二信使,动员 Ca2+ 作为 G 蛋白偶联受体的细胞外配体。Sphingosine-1-phosphate 是由鞘磷脂 (HY-113498) 或其他膜磷脂生成的重要脂质介质。 | |||
T3262 |
Phosphocreatine disodium
Disodium phosphocreatine,Phosphocreatine disodium salt,Creatine phosphate disodium salt,磷酸肌酸钠 |
Others; Endogenous Metabolite | Metabolism; Others |
Phosphocreatine disodium (Phosphocreatine disodium salt) 是一种磷酸化的肌酸分子,在肌肉、骨骼和大脑中作为一种可快速动员的高能磷酸盐储备。 | |||
T1324 |
O-Phospho-L-serine
L-Serine O-phosphate,磷酸化丝氨酸,Phosphoserine,Dexfosfoserine,L-SOP |
Amino Acids and Derivatives; Endogenous Metabolite; GluR; NMDAR | Metabolism; Neuroscience |
O-Phospho-L-serine (Phosphoserine) 是 L-serine 合成过程中的直接前体物质,是 mGluR 激动剂。 | |||
T19334 |
Galactose 1-phosphate
|
Others | Others |
Galactose 1-phosphate, an intermediate substance in both galactose metabolism and nucleotide sugar processes, plays a crucial role in the biochemical pathways involved. | |||
T19263 |
D-Glucose 6-phosphate
|
Others | Others |
D-glucose 6-phosphate is glucose that is phosphorylated on the carbon 6 hydroxyl group. | |||
T4718 |
Uridine 5'-monophosphate
Uridylic acid,尿苷5-单磷酸,UMP,Uridine phosphate,Uridine 5'-phosphoric acid,5'-Uridylic acid |
Others; Endogenous Metabolite | Metabolism; Others |
Uridine 5'-monophosphate (Uridylic acid) 是一种单磷酸盐形式的尿嘧啶核苷酸,能够由从头途径或体内核苷酸和核酸的降解产物获得,是哺乳动物乳中的主要核苷酸类似物。 | |||
T19267 |
D-Ribose 5-phosphate
|
Others | Others |
Ribose 5-phosphate is the intermediate product of the oxidative branch of the pentose phosphate pathway (PPP) and the final product of the non-oxidative branch of PPP. Ribose 5-phosphate is used in the synthesis of nucleotides and nucleic acids. | |||
T19268 |
D-Sedoheptulose 7-phosphate
|
Others | Others |
D-Sedoheptulose 7-phosphate is a common precursor of heptaic acid (group III) and hygromycin B (group IV) heptasaccharide. D-heptadecane 7-phosphate can be converted to NDP-heptose by similar biosynthetic pathways in these compounds. | |||
T78471 |
α,α-Trehalose 6-phosphate potassium
Tre6P potassium |
Endogenous Metabolite | Metabolism |
α,α-Trehalose 6-phosphate (Tre6P) potassium 是一种α,α′-trehalose的6-磷酸衍生物及内源代谢物。在Tre6P磷酸酶 (T6PP) 的催化下,α,α-Trehalose 6-phosphate可被高效转化为α,α′-trehalose。 | |||
T2971 |
Phytic acid
Inositol hexaphosphate,inositol hexakisphosphate,inositol polyphosphate,myo-Inositol, hexakis(dihydrogen phosphate),植酸,Fytic Acid |
Xanthine Oxidase; Endogenous Metabolite | Metabolism |
Phytic acid (Fytic Acid) 是种子和谷粒的磷储存化合物。它被称为食品抑制剂,具有很强的螯合多价金属离子的能力,特别是钙,铁,锌和蛋白质残留物。它抑制超氧化物来源黄嘌呤氧化酶并具有抗氧化,抗炎以及神经保护作用。 | |||
T5057 |
DL-O-Phosphoserine
DL-O-磷酸丝氨酸,DL-2-Amino-3-hydroxypropanoic acid 3-phosphate,O-PHOSPHO-L-SERINE,DL-SOP |
Others; Endogenous Metabolite | Metabolism; Others |
O-PHOSPHO-L-SERINE 是丝氨酸和磷酸的酯,是人类生物流体中的正常代谢物。O-phospho-L-serine 是一种吞噬抑制剂,抑制光损伤后的神经胶质细胞增殖和锥体细胞再生。 | |||
T16527 |
Phytic acid dodecasodium salt hydrate
植酸十二钠盐,myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate,Inositol hexaphosphate dodecasodium salt hydrate |
Others; Xanthine Oxidase; Endogenous Metabolite | Metabolism; Others |
Phytic acid dodecasodium salt hydrate (myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate) 是种子和谷物的磷储存化合物。 Phytic acid dodecasodium salt hydrate 抑制酶促超氧化物源黄嘌呤氧化酶,IC50 为 6 mM,并具有抗氧化、神经保护和抗炎作用。 | |||
T4929 |
L-2-Phosphoglyceric acid
L-GLYCERATE 3-PHOSPHATE 二钠盐,L-2-Phosphoglyceric acid disodium salt h |
Others; Endogenous Metabolite | Metabolism; Others |
L-2-Phosphoglyceric acid (L-2-Phosphoglyceric acid disodium salt) 是内源性代谢产物的一种。 | |||
T19515 |
Phosphocreatine dipotassium
Creatinephosphoric acid (dipotassium),Creatine phosphate (dipotassium) |
Others | Others |
Phosphocreatine dipotassium, primarily found in the skeletal muscles of vertebrates and one of organic compounds known as alpha amino acids and derivatives. | |||
TN7291 |
2-Deoxyribose 5-phosphate disodium
|
Others | Others |
2-Deoxyribose 5-phosphate disodium 是一种2-deoxyribose-5-phosphate aldolase (DERA) 的底物,该酶为I类醛缩酶,负责催化可逆醛缩反应,且在过程中不需要任何辅助因子。 | |||
T35951 |
Alkaline Phosphatase
|
Others | Others |
Alkaline phosphatase 是一种膜结合糖蛋白,在碱性条件下可催化磷酸单酯的水解。它可用于分子生物学和酶免分析。 | |||
T73925 |
α-D-Glucose-1-phosphate disodium hydrate
|
Others | Others |
α-D-Glucose-1-phosphate disodium hydrate 为合成葡萄糖醛酸的初始原料之一,同时,在心脏病研究领域,亦被广泛应用作为细胞抑制剂、抗生素、免疫抑制剂与循环系统研究的关键材料。 | |||
T64571 |
1,2-Dioleoyl-sn-glycero-3-phosphate, sodium salt
|
Others | Others |
1,2-Dioleoyl-sn-glycero-3-phosphate, sodium salt 是一种天然产物,可用于生命科学领域的相关研究,其产品编号为 T64571。 | |||
TN2730 |
2,5-Dihydroxybenzaldehyde
Gentisaldehyde,2,5-二羟基苯甲醛 |
Anti-infection; Antibacterial | Microbiology/Virology |
2,5-Dihydroxybenzaldehyde (Gentisaldehyde) 是一种天然抗微生物剂,可抑制Mycobacterium avium subsp. paratuberculosis 的生长。它还抑制金黄色葡萄球菌菌株,MIC50为 500 mg/L。 | |||
T5584 |
Phytic acid sodium salt
Sodium phytate hydrate,玉米 |
Others | Others |
Phytic acid sodium salt (Sodium phytate hydrate) 源于豆类种子中,具有抗营养活性。它是 [PO4]3-储藏库,是其他肌醇磷酸酯和焦磷酸酯的前体,在植物中被植酸酶逐步水解。 | |||
T10185 |
6-Phosphogluconic acid
|
Others; Endogenous Metabolite | Metabolism; Others |
6-Phosphogluconic acid 是竞争性的磷酸葡萄糖异构酶抑制剂,对6-磷酸果糖和6-磷酸葡萄糖和的 Ki 分别为 42 μM 和 48 μM。它属于人内源性代谢物。 | |||
T5073 |
Inosine 5'-monophosphate disodium salt hydrate
Inosine 5'-monophosphate disodium salt,5'-IMP-Na2,肌苷5-单磷酸二钠盐水合物,Disodium 5'-inosinate monohydrate |
Others; Endogenous Metabolite | Metabolism; Others |
Inosine 5'-monophosphate disodium salt hydrate (Inosine 5'-monophosphate disodium salt) 或肌苷酸是次黄嘌呤的核糖核苷酸,是嘌呤合成过程中形成的第一个核苷酸。 | |||
TMO2752 |
Cytidine 5'-monophosphate
5'-Cytidylic acid,5'-CMP,胞苷酸,Cytidylic Acid |
Others; Endogenous Metabolite | Metabolism; Others |
Cytidine 5'-monophosphate (5'-Cytidylic acid) 是一种核苷酸,是组成 RNA 的基本单位之一。它由核碱基胞嘧啶,戊糖核糖和磷酸基团组成。 | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00336 |
GPD2 Protein, Candida albicans, Recombinant (His)
GPD2,Glycerol-3-phosphate dehydrogenase [NAD(+)] 2 |
Candida albicans | P. pastoris (Yeast) |
GPD2 Protein, Candida albicans, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 42.3 kDa and the accession number is Q59W33. | |||
TMPY-03755 |
Glycerol 3 Phosphate Dehydrogenase/GPD1 Protein, Human, Recombinant (His)
GPDH-C,HTGTI,GPD-C,glycerol-3-phosphate dehydrogena... |
Human | E. coli |
GPD1 (Glycerol-3-Phosphate Dehydrogenase 1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. GPD1 is a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. It also reduces nicotine adenine dinucleotide... | |||
TMPH-02870 |
PDXP Protein, Mouse, Recombinant (His & SUMO)
Pdxp,Pyridoxal phosphate phosphatase,Chronophin,Pyr... |
Mouse | E. coli |
Functions as a pyridoxal phosphate (PLP) phosphatase, which also catalyzes the dephosphorylation of pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), with order of substrate preference PLP > PNP > PMP and therefore plays a role in vitamin B6 metabolism. Also functions as a protein serine phosphatase that specifically dephosphorylates 'Ser-3' in proteins of the actin-depolymerizing factor (ADF)/cofilin family like CFL1 and DSTN. Thereby, regulates cofilin-dependent actin cytoskel... | |||
TMPH-02869 |
PDXP Protein, Mouse, Recombinant (His)
Chronophin,Pdxp,Pyridoxal phosphate phosphatase,Pyr... |
Mouse | P. pastoris (Yeast) |
PDXP Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 33.5 kDa and the accession number is P60487. | |||
TMPH-01360 |
GALT Protein, Human, Recombinant (His & SUMO)
Galactose-1-phosphate uridylyltransferase,UDP-gluco... |
Human | E. coli |
Plays an important role in galactose metabolism. GALT Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 59.4 kDa and the accession number is P07902. | |||
TMPH-03257 |
CPS1 Protein, Rat, Recombinant (His & Myc)
Carbamoyl-phosphate synthase [ammonia], mitochondri... |
Rat | E. coli |
Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell. CPS1 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 23.7 kDa and the accession number is P07756. | |||
TMPY-00506 |
GAPDH Protein, Mouse, Recombinant (His)
Gapd,glyceraldehyde-3-phosphate dehydrogenase |
Mouse | E. coli |
GAPDH Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 37.9 kDa and the accession number is P16858. | |||
TMPH-01037 |
CPS1 Protein, Human, Recombinant (His)
CPS1,CPSase I,Carbamoyl-phosphate synthetase I,Carb... |
Human | E. coli |
Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell. CPS1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.5 kDa and the accession number is P31327. | |||
TMPH-02560 |
CPS1 Protein, Mouse, Recombinant (His)
Carbamoyl-phosphate synthetase I,CPS1,CPSase I,Carb... |
Mouse | E. coli |
Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell. | |||
TMPY-01651 |
RPE Protein, Human, Recombinant (His)
RPE2-1,ribulose-5-phosphate-3-epimerase |
Human | HEK293 Cells |
RPE Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27 kDa and the accession number is Q96AT9-1. | |||
TMPH-02121 |
SLC5A5 Protein, Human, Recombinant (B2M & His)
Solute carrier family 34 member 2,Sodium-dependent phosp... |
Human | E. coli |
May be involved in actively transporting phosphate into cells via Na(+) cotransport. It may be the main phosphate transport protein in the intestinal brush border membrane. May have a role in the synthesis of surfactant in lungs' alveoli. SLC5A5 Protein, Human, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 27.1 kDa and the accession number is O95436. | |||
TMPY-03019 |
RPE Protein, Mouse, Recombinant (His)
ribulose-5-phosphate-3-epimerase,2810429B02Rik,5730... |
Mouse | HEK293 Cells |
RPE Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.4 kDa and the accession number is Q8VEE0. | |||
TMPJ-00836 |
G6PD Protein, Human, Recombinant (His)
Glucose-6-Phosphate 1-Dehydrogenase,G6PD |
Human | HEK293 Cells |
Glucose-6-Phosphate 1-Dehydrogenase (G6PD) is a cytosolic enzyme that belongs to the glucose-6-phosphate dehydrogenase family. G6PD participates in the pentose phosphate pathway that supplies reducing energy to cells by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH). G6PD produces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power. NADPH in turn maintains the level of glutathione in these cells that helps protect the re... | |||
TMPH-02666 |
Fukutin Protein, Mouse, Recombinant (His & Myc)
Fktn,Fukutin,Ribitol-5-phosphate transferase FKTN,F... |
Mouse | E. coli |
Catalyzes the transfer of CDP-ribitol to the distal N-acetylgalactosamine of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). This constitutes the first step in the formation of the ribitol 5-phosphate tandem repeat which links the phosphorylated O-mannosyl trisaccharide to the ligand binding moiety composed of repeats of 3-xylosyl-alpha-1,3-glucuronic acid-b... | |||
TMPH-01990 |
PDXP Protein, Human, Recombinant (His)
PDXP,Chronophin,Pyridoxal phosphate phosphatase |
Human | Baculovirus Insect Cells |
PDXP Protein, Human, Recombinant (His) is expressed in Baculovirus. | |||
TMPH-03442 |
PMT5 Protein, S. cerevisiae, Recombinant (His)
Dolichyl-phosphate-mannose--protein mannosyltransfe... |
Saccharomyces cerevisiae | E. coli |
Protein O-mannosyltransferase involved in O-glycosylation which is essential for cell wall rigidity. Forms a heterodimeric complex with PMT3 and more rarely with PMT2 to transfer mannose from Dol-P-mannose to Ser or Thr residues on proteins. PMT5 Protein, S. cerevisiae, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 38.6 kDa and the accession number is P52867. | |||
TMPY-02446 |
GAPDH Protein, Human, Recombinant (His)
G3PD,GAPD,HEL-S-162eP,glyceraldehyde-3-phosphate de... |
Human | E. coli |
GAPDH Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 38 kDa and the accession number is P04406. | |||
TMPH-00515 |
PPDK Protein, Entamoeba histolytica, Recombinant (His & SUMO)
PPDK,Pyruvate, orthophosphate dikinase,Pyruvate, |
Entamoeba histolytica | E. coli |
Catalyzes the reversible phosphorylation of pyruvate and phosphate. In E.histolytica and C.symbiosus, PPDK functions in the direction of ATP synthesis. | |||
TMPH-00422 |
Ppdk Protein, Clostridium symbiosum, Recombinant (His & Myc)
ppdK,Pyruvate, orthophosphate dikinase,Pyruvate, |
Clostridium symbiosum | E. coli |
Catalyzes the reversible phosphorylation of pyruvate and phosphate. In E.histolytica and C.symbiosus, PPDK functions in the direction of ATP synthesis. Ppdk Protein, Clostridium symbiosum, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 20.5 kDa and the accession number is P22983. | |||
TMPJ-01034 |
TIM Protein, Human, Recombinant (His)
TPI1,TPI,Triose-Phosphate Isomerase,Triosephosp... |
Human | E. coli |
Triose-phosphate isomerase, also named Triose-phosphate isomerase, TPI and TIM, is an enzyme that catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate. TPI has been found in nearly every organism searched for the enzyme, including animals such as mammals and insects as well as in fungi, plants, and bacteria. However, some bacteria that do not perform glycolysis, like ureaplasmas, lack TPI. TPI plays an important role... | |||
TMPH-03441 |
PMT3 Protein, S. cerevisiae, Recombinant (His)
Dolichyl-phosphate-mannose--protein mannosyltransfe... |
Saccharomyces cerevisiae | E. coli |
Protein O-mannosyltransferase involved in O-glycosylation which is essential for cell wall rigidity. Forms a heterodimeric complex with PMT5 and more rarely with PMT1 to transfer mannose from Dol-P-mannose to Ser or Thr residues on proteins. Seems to have redundant activity to PMT2. PMT3 Protein, S. cerevisiae, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 39.6 kDa and the accession number is P47190. | |||
TMPH-00575 |
GlpD Protein, E. coli, Recombinant (His)
glpD,Aerobic glycerol-3-phosphate dehydrogenase |
E. coli | E. coli |
Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses molecular oxygen or nitrate as electron acceptor. GlpD Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 60.8 kDa and the accession number is P13035. | |||
TMPH-02429 |
Fukutin Protein, Cynomolgus, Recombinant (His & Myc)
FKTN,Fukutin,Fukuyama-type congenital muscular dystrophy pro... |
Cynomolgus | E. coli |
Fukutin Protein, Cynomolgus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 58.0 kDa and the accession number is Q60HG0. | |||
TMPJ-00520 |
NANS Protein, Human, Recombinant (His)
N-Acetylneuraminic Acid Synthase,N-Acetylneuraminic Acid |
Human | E. coli |
Sialic Acid Synthase (NANS) is an enzyme that contains one AFP-like domain. NANS is ubiquitous and plays a role in the biosynthetic pathways of sialic acids. NANS produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN). It also can use N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively. | |||
TMPH-02299 |
UGP2 Protein, Human, Recombinant (His & SUMO)
UDP-glucose pyrophosphorylase,UTP--glucose-1-phosphate |
Human | E. coli |
UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen. | |||
TMPH-02988 |
UGPA Protein, Musa acuminata, Recombinant (His & Myc)
UGPA,UDP-glucose pyrophosphorylase,UTP--glucose-1-phosph... |
Musa acuminata | E. coli |
Plays a central role as a glucosyl donor in cellular metabolic pathways. UGPA Protein, Musa acuminata, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 58.8 kDa and the accession number is Q9SDX3. | |||
TMPH-00041 |
EPSP synthase Protein, Agrobacterium sp., Recombinant (His & SUMO)
3-phosphoshikimate 1-carboxyvinyltransferase,aroA,5-enolpyru... |
Agrobacterium | E. coli |
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. EPSP synthase Protein, Agrobacterium sp., Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 63.6 kDa and the accession number is Q9R4E4. | |||
TMPH-00566 |
EPSP synthase Protein, E. coli, Recombinant (His & Myc)
5-enolpyruvylshikimate-3-phosphate synthase,3-phosp... |
E. coli | E. coli |
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. EPSP synthase Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 53.5 kDa and the accession number is P0A6D3. | |||
TMPH-01858 |
PIP4K2B Protein, Human, Recombinant (His)
Diphosphoinositide kinase 2-beta,Phosphatidylinositol 5-... |
Human | E. coli |
PIP4K2B Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 53.3 kDa and the accession number is P78356. | |||
TMPH-00439 |
GAPDH Protein, Cricetulus griseus, Recombinant (His)
Glyceraldehyde-3-phosphate dehydrogenase,Peptidyl-c... |
Chinese hamster | E. coli |
GAPDH Protein, Cricetulus griseus, Recombinant (His) is expressed in E. coli. | |||
TMPH-00664 |
EPSP synthase Protein, E. coli O157:H7, Recombinant (His & Myc)
5-enolpyruvylshikimate-3-phosphate synthase,3-phosp... |
E. coli | E. coli |
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | |||
TMPH-00040 |
EPSP synthase Protein, Agrobacterium sp., Recombinant (His)
3-phosphoshikimate 1-carboxyvinyltransferase,5-enolpyruvylsh... |
Agrobacterium | HEK293 Cells |
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. EPSP synthase Protein, Agrobacterium sp., Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis-Myc tag. The predicted molecular weight is 51.6 kDa and the accession number is Q9R4E4. | |||
TMPH-03189 |
EPSP synthase Protein, Pseudomonas sp., Recombinant (His & Myc)
5-enolpyruvylshikimate-3-phosphate synthase,3-phosp... |
Pseudomonas | E. coli |
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. EPSP synthase Protein, Pseudomonas sp., Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 54.7 kDa and the accession number is P0A2Y4. | |||
TMPH-00557 |
DXP reductoisomerase Protein, E. coli, Recombinant (His & Myc)
1-deoxy-D-xylulose 5-phosphate reductoisomerase,DXP... |
E. coli | E. coli |
Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). | |||
TMPH-00370 |
GAPDH Protein, Chicken, Recombinant (His)
Peptidyl-cysteine S-nitrosylase GAPDH,GAPDH,Glyceraldehyde-3... |
Chicken | E. coli |
GAPDH Protein, Chicken, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 39.6 kDa and the accession number is P00356. | |||
TMPH-03303 |
GPI Protein, Rat, Recombinant (His & Myc)
Phosphoglucose isomerase,Gpi,Phosphohexose isomerase,Autocri... |
Rat | E. coli |
GPI Protein, Rat, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-03057 |
Chorismate synthase Protein, Neurospora crassa, Recombinant (His)
B7F21.10,NCU05420,aro-2,5-enolpyruvylshikimate-3-phospha... |
Neurospora crassa | E. coli |
Bifunctional enzyme that possesses chorismate synthase and intrinsic flavin reductase activity, it uses NADPH to reduce FMN. | |||
TMPY-01189 |
GFPT1 Protein, Human, Recombinant
GFAT1,CMSTA1,GFAT,glutamine--fructose-6-phosphate t... |
Human | E. coli |
Glutamine:fructose-6-phosphate amidotransferase 1 (GFAT), also known as GFPT1, is a member of the N-terminal nucleophile aminotransferases and the first rate-limiting enzyme for the entry of glucose into the hexosamine biosynthesis pathway (HBP) in mammals. GFAT transfers the amino group from the L-glutamine amide to the D-fructose 6-phosphate, producing glutamic acid and glucosamine 6-phosphate. GFAT exists as a homotetramer in cytoplasm, and is proposed to be most likely involved in re... | |||
TMPH-01400 |
GPD2 Protein, Human, Recombinant (His & Myc)
GPD2,mitohondrial glycerophosphate dehydrogenase ge... |
Human | E. coli |
Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device. GPD2 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 81.4 kDa and the accession number is P43304. | |||
TMPH-00626 |
GPR Protein, E. coli, Recombinant (His)
proA,Glutamyl-gamma-semialdehyde dehydrogenase,Gamma-glutamy... |
E. coli | E. coli |
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. GPR Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 48.7 kDa and the accession number is P07004. | |||
TMPH-00732 |
RtcB Protein, E. coli, Recombinant (His)
rtcB,3'-phosphate/5'-hydroxy nucleic acid ligase,RN... |
E. coli | P. pastoris (Yeast) |
GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends. Also acts as a DNA ligase in case of DNA damage by splicing 'dirty' DNA breaks, characterized by 3'-phosphate (or cyclic-phosphate) and 5'-hydroxy ends that cannot be sealed by classical DNA ligases. | |||
TMPH-00093 |
GAPC1, cytosolic Protein, Arabidopsis thaliana, Recombinant (His & Myc)
NAD-dependent glyceraldehydephosphate dehydrogenase... |
Arabidopsis thaliana | E. coli |
GAPC1, cytosolic Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 44.4 kDa and the accession number is P25858. | |||
TMPH-03429 |
DOG1 Protein, S. cerevisiae, Recombinant (His)
DOG1,2-DOG-6-P 1,2-deoxyglucose-6-phosphatase 1,2-deoxygluco... |
Saccharomyces cerevisiae | P. pastoris (Yeast) |
Active on 2-DOG-6P, also very active on fructose-1P. DOG1 Protein, S. cerevisiae, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 29.1 kDa and the accession number is P38774. | |||
TMPH-02677 |
GPI Protein, Mouse, Recombinant (B2M & His)
Gpi,Phosphohexose isomerase,Phosphoglucose isomerase,Neurole... |
Mouse | E. coli |
In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion. | |||
TMPH-02678 |
GPI Protein, Mouse, Recombinant (His)
Phosphoglucose isomerase,Autocrine motility factor,Glucose-6... |
Mouse | P. pastoris (Yeast) |
In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion. GPI Protein, Mous... | |||
TMPH-02379 |
arnT Protein, Klebsiella pneumoniae, Recombinant (His)
Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase,4-amino-... |
Klebsiella pneumoniae | E. coli |
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. | |||
TMPJ-00978 |
PIP4K2A Protein, Human, Recombinant (His)
Diphosphoinositide kinase 2-α,PtdIns(5)P-4-kinase isoform 2-... |
Human | HEK293 Cells |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (PIP4K2A) is a member of the phosphatidylinositol-4-phosphate 5-kinase family. It contains 1 PIPK domain and is expressed ubiquitously, with high levels in the brain. It catalyzes the phosphorylation of phosphatidylinositol 5-phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). It may exert its function by regulating the levels of PtdIns5P, which functions in the... | |||
TMPH-01391 |
GPI Protein, Human, Recombinant (His)
Sperm antigen 36,Neuroleukin,Glucose-6-phosphate is... |
Human | E. coli |
In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion. GPI Protein, Huma... | |||
TMPH-00556 |
1-AGPAT Protein, E. coli, Recombinant (His)
1-AGP acyltransferase,1-AGPAT,LPAAT,1-acyl-sn-glycerol-3- |
E. coli | P. pastoris (Yeast) |
Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor. 1-AGPAT Protein, E. coli, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 29.5 kDa and the accession number is P26647. | |||
TMPH-00846 |
ABHD5 Protein, Human, Recombinant (His & SUMO)
Abhydrolase domain-containing protein 5,1-acylglycerol-3- |
Human | E. coli |
ABHD5 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 55.0 kDa and the accession number is Q8WTS1. | |||
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Cat. No. | Product Name | Target | Signaling Pathways |
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TMIJ-0399 |
Triphenyl-d15 Phosphate
|
||
Triphenyl-d15 Phosphate 是 Triphenyl Phosphate 的氘代化合物。Triphenyl Phosphate 的 CAS 号为 115-86-6。 | |||
TMIJ-0400 |
Tri-n-butyl-d27 Phosphate
|
||
Tri-n-butyl-d27 Phosphate 是 Tri-n-butyl Phosphate 的氘代化合物。Tri-n-butyl Phosphate 的 CAS 号为 126-73-8。 | |||
TMID-0305 |
Vitamin B1 Pyrophosphate-d3
|
||
Vitamin B1 Pyrophosphate-d3 是 Vitamin B1 Pyrophosphate 的氘代化合物。 | |||
TMIJ-0061 |
Oseltamivirphosphate-d5
|
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Oseltamivirphosphate-d5 是 Oseltamivirphosphate 的氘代化合物。Oseltamivirphosphate 的 CAS 号为 204255-11-8。 | |||
T19249 |
Creatinine-D3
NSC13123-D3,氘代肌酸酐 |
Others | Others |
Creatinine-D3 is a deuterium-labeled Creatinine which is a break-down product of creatine phosphate in muscle. | |||
T37119 |
1,2,3-Trioctanoyl-rac-glycerol-13C3
1,2,3-Trioctanoyl-rac-glycerol-13C3 |
||
1,2,3-Trioctanoyl-rac-glycerol-13C3 is intended for use as an internal standard for the quantification of 1,2,3-trioctanoyl-rac-glycerol by GC- or LC-MS. 1,2,3-Trioctanoyl-rac-glycerol is a triacylglycerol that contains octanoic acid at the sn-1, sn-2, and sn-3 positions. Dietary administration of 1,2,3-trioctanoyl-rac-glycerol increases hippocampal levels of the glycolytic metabolites glucose 6-phosphate, fructose 6-phosphate, and β-hydroxybutyrate and the seizure threshold in the 6 Hz psychomo... | |||
TMIJ-0230 |
Oseltamivir EP Impurity C-d3 HCl
|
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Oseltamivir EP Impurity C-d3 HCl 是 Oseltamivir EP Impurity C HCl 的氘代化合物。Oseltamivir EP Impurity C HCl 的 CAS 号为 1415963-60-8。 | |||
TMID-0163 |
myo-Inositol-d6
|
||
myo-Inositol-d6 是 myo-Inositol 的氘代化合物。myo-Inositol 的 CAS 号为 87-89-8。Inositol是一种细胞内磷酸化合物,参与细胞信号传导,可能刺激肿瘤细胞分化。 | |||
TMID-0219 |
Malachite green-d5 oxalate
|
||
Malachite green-d5 oxalate 是 Malachite green oxalate 的氘代化合物。Malachite green oxalate 的 CAS 号为 2437-29-8。Malachite green oxalate 是一种三苯基甲烷染料,可用于检测酶促反应中磷酸盐的释放。它也是一种选择性IKBKE抑制剂,在体内外均表现出抗肿瘤活性。 | |||
TMIH-0236 |
Fingolimod-d4 HCl
|
||
Fingolimod-d4 HCl 是 Fingolimod HCl 的氘代化合物。Fingolimod HCl 的 CAS 号为 162359-56-0。Fingolimod hydrochloride 是一种新型免疫调节剂,是一种 1-磷酸鞘氨醇 (S1P) 拮抗剂,作用于 K562 和 NK 细胞,IC50为 0.033 nM。它诱导 S1P1 的内化,从而抑制 S1P 活性。它被鞘氨醇激酶磷酸化,尤其是被 SK2 磷酸化,从而可与 S1PR1、3、4 和 5 结合 | |||
TMID-0152 |
Pyridoxine-d2 HCl
|
||
Pyridoxine-d2 HCl 是 Pyridoxine HCl 的氘代化合物。Pyridoxine HCl 的 CAS 号为 58-56-0。Pyridoxine hydrochloride 是一种吡啶衍生物。在于阿尔茨海默病细胞模型中,通过Nrf-2/HO-1 途径发挥抗氧化作用。 | |||
TMIJ-0071 |
Oseltamivir-13C-d3 Acid
|
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Oseltamivir-13C-d3 Acid 是 Oseltamivir Acid 的 13C 和氘代化合物。Oseltamivir Acid 的 CAS 号为 187227-45-8。Oseltamivir acid是Oseltamivir phosphate 的活性代谢产物,是一种有效的流感病毒神经氨酸酶抑制剂和 GS4071 的前药。 |