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Search Results for " transferase "
Targets Recommended: DNA Methyltransferase Histone Acetyltransferase Histone Methyltransferase Methionine Adenosyltransferase (MAT) Acyltransferase N-Acetylglucosaminyltransferase Transferase NF-κB Rho

147

抑制剂 & 化合物

30

天然产物

93

重组蛋白

1

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T25450 GGTI 2147

GGTI2147,Geranylgeranyl transferase inhibitor-2147,GGTI-2147

NF-κB; Rho Cell Cycle/Checkpoint; NF-κB
GGTI 2147 降低 Rac1 活性,下调 p65 的表达,改善 OGD/R 诱导的神经元凋亡。
T82343 Gamma-Glutamyl Transferase-IN-1

Others Others
Gamma-Glutamyl Transferase-IN-1 (compound 4de) 是一种 β-羰基酰肼类抑制剂,靶向谷氨酰转移酶,具有抗真菌和抗菌活性。它通过促进活性氧积累、破坏细胞膜和失调组蛋白乙酰化来发挥作用。
T82342 Gamma-Glutamyl Transferase-IN-2

Others Others
Gamma-Glutamyl Transferase-IN-2 (compound 4dq),一种β-羰基酰肼类抑制剂,针对谷氨酰转移酶 (gamma-glutamyl transferase),展现其抗真菌与抗菌活性。该化合物通过诱导活性氧积累、破坏细胞膜以及干扰组蛋白乙酰化来发挥其生物学效应。
T11282 FGTI-2734

Transferase Metabolism
FGTI-2734 是 有效的RAS C-末端法尼基转移酶 (FT) 和香叶烯基转移酶-1 (GGT-1) 抑制剂,IC50s 分别为 250 nM 和 520 nM。 它可以阻断 KRAS 的膜定位,从而解决 KRAS 耐药性问题,并抑制突变的 KRAS 胰腺肿瘤。
T9626 Cycloleucine

NMDAR Neuroscience
Cycloleucine 是 NMDA 受体相关甘氨酸受体的拮抗剂,Ki 为 600 μM。Cycloleucine 也是 S-腺苷甲硫氨酸介导的甲基化的竞争性抑制剂,具有抗焦虑和细胞抑制作用。
T11505 GSTO1-IN-1

Glutathione Peroxidase; GST Metabolism; oxidation-reduction
GSTO1-IN-1 是谷胱甘肽 S-转移酶 omega 1 抑制剂,IC50=31 nM。
T6302 Lonafarnib

Sarasar,氯那法尼,Sch66336

Raf; Transferase; Autophagy; Ras Autophagy; GPCR/G Protein; MAPK; Metabolism
Lonafarnib (Sch66336) 是一种可口服的 FPTase 抑制剂,作用于 H-ras、K-ras 和 N-ras,IC50分别为 1.9 nM、5.2 nM 和 2.8 nM。它具有抗肝炎三角洲病毒的活性。
T4335 GNE-617

GNE617

NAMPT Metabolism
GNE-617 是一种新型的、特异性的Nampt 抑制剂,在A549细胞中IC50为18.9nM。
T2678 LB42708

Transferase Metabolism
LB42708 是一种口服有活力的特异性法尼基转移酶抑制剂。它对H-Ras、N-Ras 和K-Ras4B 的法尼基化均有抑制作用,其IC50分别为 0.8 nM、1.2 nM 和 2.0 nM。
T12171 Nampt-IN-5

P450; NAMPT Metabolism
Nampt-IN-5 是烟酰胺磷酸核糖基转移酶抑制剂。它可抑制 A2780 和 COR-L23 细胞,IC50值分别为 0.7 nM 和 3.9 nM。它还抑制 CYP3A4 活性。
T6682 STF-118804

STF 118804,STF118804

Apoptosis; NAMPT Apoptosis; Metabolism
STF-118804是一种烟酰胺磷酸核糖基转移酶 Nampt 高选择性抑制剂,降低大多数 B-ALL 细胞系的活力,IC50 <10 nM。
T4376 Nampt-IN-1

LSN3154567

c-Fms; NAMPT; CSF-1R Metabolism; Tyrosine Kinase/Adaptors
Nampt-IN-1 (LSN3154567) 是选择性的 NAMPT 抑制剂,能够抑制纯化的 NAMPT,IC50=3.1 nM。
T2700 FTI-277 hydrochloride

FTI 277 HCl

Apoptosis; Transferase; Ras Apoptosis; GPCR/G Protein; MAPK; Metabolism
FTI-277 hydrochloride (FTI 277 HCl) 是一种法尼基转移酶FTase 抑制剂,高效 Ras CAAX 肽模拟物,可抑制H-Ras 和K-Ras 信号转导,还可抑制hepatitis delta virus 感染。
T38050 CP-609754

Transferase Metabolism
CP-609754 是高效的、可逆的法尼基转移酶抑制剂,对重组人 H-Ras 和重组 K-Ras 法尼基化的 IC50分别为 0.57 ng/mL 和 46 ng/mL。CP-609754有潜在的抗癌作用。
T3182 L-778123 hydrochloride

L 778123

Telomerase; Transferase DNA Damage/DNA Repair; Metabolism
L-778123 hydrochloride 是一种FPTase 和GGPTase-I 双重抑制剂,IC50分别为2 nM 和 98 nM。
T16409 OSMI-1

Others; Acyltransferase Metabolism; Others
OSMI-1 是一种 O-GlcNAc 转移酶 (OGT) 抑制剂 (IC50=2.7 μM),具有口服活性和细胞渗透性。OSMI-1 可以抑制蛋白质 O-GlcNA 酰化,而不会定性地改变细胞表面 N- 或 O- 连接的聚糖。
T6271 Tipifarnib

替吡法尼,R115777,Zarnestra,IND 58359

Transferase Metabolism
Tipifarnib (IND 58359) 能够抑制法尼基转移酶 (FTase),IC50=0.86 nM,具有潜在抗肿瘤特性。
T1998 CHS-828

CHS 828,GMX1778

Apoptosis; NAMPT Apoptosis; Metabolism
CHS-828 (GMX1778) 是一种竞争性的烟酰胺磷酸化转移酶抑制剂,IC50值 <25 nM。它通过降低细胞中的 NAD+水平发挥细胞毒性作用,具有抗癌活性。
T4564 Ethacrynic acid

Edecrin,利尿酸,Etacrynic Acid,Hydromedin

Others; Calcium Channel; NF-κB; GST Membrane transporter/Ion channel; Metabolism; NF-κB; Others; oxidation-reduction
Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂,也是NF-κB 信号传导途径的有效抑制剂,并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道,从而导致气道平滑肌细胞松弛。它是利尿剂,具有抗炎特性,可减轻类维生素 A 诱导的小鼠耳部水肿。
T5097 Ezatiostat

TER199(free base),TLK199

Apoptosis; Glutathione Peroxidase; GST Apoptosis; Metabolism; oxidation-reduction
Ezatiostat (TER199(free base)) 是一种谷胱甘肽的三肽类似物,也是一种选择性的口服活性的谷胱甘肽 S-转移酶 P1-1 (GSTP1) 抑制剂。它通过抑制GSTP1导致 JNK 激活,刺激淋巴细胞生成和骨髓祖细胞增殖,可研究骨髓增生异常综合症。
T12854 SBI-797812

NAMPT Metabolism
SBI-797812 是在结构上类似于活性位点定向的 NAMPT 抑制剂的化合物,能够阻断这些抑制剂与 NAMPT 的结合。 它将 NAMPT 反应平衡转向 NMN 形成,提高 NAMPT 对 ATP 的亲和力,稳定 His247 处的磷酸化 NAMPT,增加焦磷酸盐副产物的消耗,并通过 NAD+钝化反馈抑制。
T22665 PD 128042

CI 976

Acyltransferase Metabolism
PD 128042 (CI 976) 是口服有效的ACAT (酰基辅酶 A: 胆固醇酰基转移酶)选择性抑制剂。它也是LPAT(溶血磷脂酰基转移酶) 抑制剂。它抑制高尔基体相关 LPAT 活性 (IC50=15 μM)。它抑制多种膜运输步骤,包括在内吞和分泌途径中发现的步骤。
T17102 Tipifarnib (S enantiomer)

Tipifarnib S enantiomer,(S)-(-)-R-115777,(S)-Tipifarnib,IND-58359 S enantiomer

Transferase Metabolism
Tipifarnib S enantiomer ((S)-(-)-R-115777) 是Tipifarnib 的 S 型对映体,它比 Tipifarnib 特性低。其中 Tipifarnib 是farnesyltransferase 高效特异性抑制剂,IC50=0.6 nM。
T2644 (E)-Daporinad

Daporinad,(E)-N-[4-(1-BENZOYL-PIPERIDIN-4-YL)-BUTYL]-3-PYRIDIN-3-YL-ACRYLAMIDE,APO866,FK866,达珀利奈

NAMPT; Transferase; Autophagy Autophagy; Metabolism
(E)-Daporinad (FK866) 是一种烟酰胺磷酸核糖基转移酶的小分子抑制剂,具有潜在的抗肿瘤和抗血管生成活性,IC50为 0.09 nM。
T22776 Ezatiostat hydrochloride

TLK199 HCl,Ezatiostat盐酸盐,TER199

Glutathione Peroxidase Metabolism
Ezatiostat hydrochloride (TLK199 HCl) 是一种新型谷胱甘肽类似物,可刺激淋巴细胞生成和骨髓祖细胞增殖,可用于治疗血细胞减少症和研究骨髓增生异常综合症。它也是口服活性的选择性谷胱甘肽 S-转移酶 P1-1 抑制剂,通过抑制 GSTP1导致 JNK 激活。
T77560 Histone acetyltransferase p300 Inhibitor 4c

Carbonic Anhydrase; AChE Metabolism; Neuroscience
Histone acetyltransferase p300 Inhibitor 4c 是2-氨基噻唑衍生物,Histone acetyltransferase p300 Inhibitor 4c 对 hCA I 、hCA II、AChE 和 BChE 具有抑制作用,Ki 值为 0.008 ± 0.001 、 0.124 ± 0.017、0.129 ± 0.030 和 0.083 ± 0.041 μM。
T61037 Glycosyltransferase-IN-1

Others Others
Glycosyltransferase-IN-1 是一种糖基转移酶 (glycosyltransferase) 抑制剂,具有抑菌活性,抑制 MSSA、MRSA 、枯草杆菌和肠杆菌。
T11563 Histone Acetyltransferase Inhibitor II

Epigenetic Reader Domain; Histone Acetyltransferase Chromatin/Epigenetic
Histone Acetyltransferase Inhibitor II 是一种选择性的细胞渗透性 p300 组蛋白乙酰转移酶抑制剂,IC50值为 5 µM。它在哺乳动物细胞中具有抗乙酰化酶活性,可用于癌症研究。
T75416 alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138)

Others Others
alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138) (EC 2.4.1.40(Pm1138)),是一种ABO系统转移酶,具备糖基转移酶活性。
T76158 Phosphate acetyltransferase

Others Others
Phosphate acetyltransferase (磷酸乙酰转移酶) 为一转移酶类,主要应用于生化领域。该酶通过将乙酰基从 acetyl-P 可逆地转移至 CoA,生成 acetyl-CoA 及无机磷酸盐,从而参与乙酸的同化及异化过程。
T75418 alpha-1,3-Galactosyltransferase (GTB)

Others Others
Alpha-1,3-Galactosyltransferase (GTB) 催化异种抗原或 α-半乳糖 (α-Gal) 表位的合成,通过将 UDP-Gal 中的半乳糖转移到类型1或类型2的 αFuc1→2βGal-R (H)-终止受体上。
T63737 Purine phosphoribosyltransferase-IN-1

Others Others
Purinephosphoribosyltransferase-IN-1 (Compound (S,R)-48) 是一种有效的恶性疟原虫 (Pf)、间日疟原虫 (Pv) 和布氏锥虫 (Tbr) 6-氧嘌呤磷酸核糖基转移酶 (PRT) 抑制剂,他们的 Ki 值分别为 50、20 和 2 nM。
T11037 Diacylglycerol acyltransferase inhibitor-1

Others Others
Diacylglycerol Acyltransferase Inhibitor-1, a diacylglycerol acyltransferase (DGAT1) inhibitor, effectively suppresses the activity of DGAT1.
T78364 Alanine aminotransferase

Endogenous Metabolite Metabolism
Alanine aminotransferase是一种酶,能促进L-丙氨酸与2-氧代谷氨酸之间可逆的转化为丙酮酸和L-谷氨酸。
T75389 Catechol O-methyltransferase

COMT

Endogenous Metabolite Metabolism
Catechol O-methyltransferase (COMT) 是是调节褪黑激素合成的关键酶,可调节参与调节植物的生长发育,可被具有特定结构的肝素低聚糖抑制。
T75414 alpha-1,4-Galactosyltransferase (LgtC)

Others Others
alpha-1,4-Galactosyltransferase (LgtC) (A4GALT) 为特异性糖基转移酶,专门将半乳糖转移到乳糖苷神经酰胺的α-1,4位,通过此作用生成三糖神经酰胺。此外,alpha-1,4-Galactosyltransferase (LgtC) 在合成P1血型抗原方面有应用价值。
T78352 N-acetylglucosamine-1-P uridyltransferase (AGX1)

GlcNAc1pUT

Others Others
N-acetylglucosamine-1-P uridyltransferase (AGX1) (GlcNAc1pUT) 是具有双功能乙酰转移酶/尿苷转移酶活性的原核生物专有酶。该酶能结合GlcNAc-1-P与UTP,催化合成UDP-GlcNAc的尿苷酰转移反应。
T63738 Purine phosphoribosyltransferase-IN-2

Others Others
Purine phosphoribosyltransferase-IN-2 是一种有效的恶性疟原虫 (Pf),间日疟原虫 (Pv) 以及布氏锥虫 (Tbr) 6-氧嘌呤磷酸核糖基转移酶 (PRT) 抑制剂,他们的Ki 值分别为 30、20 和 2 nM。
T75420 alpha-1,3/4-Fucosyltransferase (α1,3/4FucT)

Others Others
alpha-1,3/4-Fucosyltransferase (α1,3/4FucT) (Hp3/4FT) 存在于幽门螺杆菌中。alpha-1,3/4-Fucosyltransferase (α1,3/4FucT) 催化岩藻糖从供体 GDP-β-l-岩藻糖转移到 GlcNAc。
T75417 alpha-1,3-Galactosyltransferase (a1,3GalT)

Others Others
α-1,3-Galactosyltransferase (a1,3GalT) (GGTA1) 能够将UDP中的半乳糖 (Gal) 通过α1-3键转移到糖蛋白的N-乙酰乳糖胺 (Galβ1,4GlcNAc-R) 上。该酶主要参与合成α-半乳糖 (α-Gal) 表位,此种表位在大多数哺乳动物中普遍存在。
T75419 alpha-2,8-Sialyltransferase (CstII)

Others Others
alpha-2,8-Sialyltransferase (CstII) (ST8Sia VI),属于alpha2,8-sialyltransferase (ST8Sia) 家族,广泛应用于生化研究中。该酶负责催化Sia残基通过α2,8键连接形成的寡聚/聚唾液酸链的延伸。
T78353 alpha-2,6-Sialyltransferase (Pd26ST)

Others Others
alpha-2,6-Sialyltransferase (Pd26ST) 能够催化末端和内部半乳糖及N-乙酰半乳糖胺的唾液酸化,形成末端α2,6-唾液酸苷。
T75399 GlcNAc 1-P uridyltransferase (CjGlmU)

Others Others
GlcNAc 1-P uridyltransferase (CjGlmU) 为一种糖核苷酸转移酶,以UTP和GlcNAc-1-P为天然底物,负责合成UDP-GlcNAc。此酶展现出潜在的抗菌活性分子研究价值。
T75413 beta-1,4-Galactosyltransferase (LgtB)

Others Others
beta-1,4-Galactosyltransferase (LgtB) (B4GALT1 (LgtB)) 通常用于生化研究。beta-1,4-Galactosyltransferase (LgtB) 催化涉及 UDP-半乳糖和 N-乙酰葡糖胺的反应,用于生产半乳糖 β-1,4-N-乙酰葡糖胺。
T13429 α-2,3-sialyltransferase-IN-1

Lith-O-Asp analog

Others Others
α-2,3-sialyltransferase-IN-1 is a noncompetitive inhibitor of α-2,3-sialyltransferase(IC50 of 6 μM).
T76178 Aspartate aminotransferase

Aspartate aminotransferase (AST) 是一种转氨酶,常用于生化研究。Aspartate aminotransferase 催化天冬氨酸和 α-酮戊二酸转化为草酰乙酸和谷氨酸。Aspartate aminotransferase 可存在于在脑脊液、渗出液和渗出物。
T75421 alpha-2,3-Sialyltransferase (PmST3)

Others Others
alpha-2,3-Sialyltransferase (PmST3) 是一种 β-半乳糖苷透过酶。alpha-2,3-Sialyltransferase (PmST3) 催化唾液酸转移至糖蛋白和糖脂的碳水化合物基团。
T75415 beta-1,3-Galactosyltransferase (CgtB)

Others Others
beta-1,3-Galactosyltransferase (CgtB) (GM1-synthase) 为生化研究中常用的酶,负责催化半乳糖分子的加成,以生产含有 GM1-like LOSSIAL 结构的唾液化低脂糖(LOSSIAL)。
T75411 beta-1, 3-N-Acetylhexaminyltransferase (LgtA)

Others Others
Beta-1, 3-N-Acetylhexaminyltransferase (LgtA) 是一种糖基转移酶,在生化研究中常见。该酶主要催化作用为将 N-乙酰葡糖胺从 UDP-GlcNAc 转移到 N-乙酰乳糖胺和乳糖上。
T11504 GSTO-IN-2

Others Others
GSTO-IN-2 is a glutathione S-transferase inhibitor (IC50s: 1.4, 16.3, and 3.6 μM for GSTP1-1, GSTM1, and GSTA2).

化合物

GGTI 2147
Cat.No: T25450
Synonym: GGTI2147,Geranylgeranyl transferase inhibitor-2147,GGTI-2147
Target: NF-κB, Rho
Gamma-Glutamyl Transferase-IN-1
Cat.No: T82343
Synonym:
Target: Others
Gamma-Glutamyl Transferase-IN-2
Cat.No: T82342
Synonym:
Target: Others
FGTI-2734
Cat.No: T11282
Synonym:
Target: Transferase
Cycloleucine
Cat.No: T9626
Synonym:
Target: NMDAR
GSTO1-IN-1
Cat.No: T11505
Synonym:
Target: Glutathione Peroxidase, GST
Lonafarnib
Cat.No: T6302
Synonym: Sarasar,氯那法尼,Sch66336
Target: Raf, Transferase, Autophagy, Ras
GNE-617
Cat.No: T4335
Synonym: GNE617
Target: NAMPT
LB42708
Cat.No: T2678
Synonym:
Target: Transferase
Nampt-IN-5
Cat.No: T12171
Synonym:
Target: P450, NAMPT
STF-118804
Cat.No: T6682
Synonym: STF 118804,STF118804
Target: Apoptosis, NAMPT
Nampt-IN-1
Cat.No: T4376
Synonym: LSN3154567
Target: c-Fms, NAMPT, CSF-1R
FTI-277 hydrochloride
Cat.No: T2700
Synonym: FTI 277 HCl
Target: Apoptosis, Transferase, Ras
CP-609754
Cat.No: T38050
Synonym:
Target: Transferase
L-778123 hydrochloride
Cat.No: T3182
Synonym: L 778123
Target: Telomerase, Transferase
OSMI-1
Cat.No: T16409
Synonym:
Target: Others, Acyltransferase
Tipifarnib
Cat.No: T6271
Synonym: 替吡法尼,R115777,Zarnestra,IND 58359
Target: Transferase
CHS-828
Cat.No: T1998
Synonym: CHS 828,GMX1778
Target: Apoptosis, NAMPT
Ethacrynic acid
Cat.No: T4564
Synonym: Edecrin,利尿酸,Etacrynic Acid,Hydromedin
Target: Others, Calcium Channel, NF-κB, GST
Ezatiostat
Cat.No: T5097
Synonym: TER199(free base),TLK199
Target: Apoptosis, Glutathione Peroxidase, GST
SBI-797812
Cat.No: T12854
Synonym:
Target: NAMPT
PD 128042
Cat.No: T22665
Synonym: CI 976
Target: Acyltransferase
Tipifarnib (S enantiomer)
Cat.No: T17102
Synonym: Tipifarnib S enantiomer,(S)-(-)-R-115777,(S)-Tipifarnib,IND-58359 S enantiomer
Target: Transferase
(E)-Daporinad
Cat.No: T2644
Synonym: Daporinad,(E)-N-[4-(1-BENZOYL-PIPERIDIN-4-YL)-BUTYL]-3-PYRIDIN-3-YL-ACRYLAMIDE,APO866,FK866,达珀利奈
Target: NAMPT, Transferase, Autophagy
Ezatiostat hydrochloride
Cat.No: T22776
Synonym: TLK199 HCl,Ezatiostat盐酸盐,TER199
Target: Glutathione Peroxidase
Histone acetyltransferase p300 Inhibitor 4c
Cat.No: T77560
Synonym:
Target: Carbonic Anhydrase, AChE
Glycosyltransferase-IN-1
Cat.No: T61037
Synonym:
Target: Others
Histone Acetyltransferase Inhibitor II
Cat.No: T11563
Synonym:
Target: Epigenetic Reader Domain, Histone Acetyltransferase
alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138)
Cat.No: T75416
Synonym:
Target: Others
Phosphate acetyltransferase
Cat.No: T76158
Synonym:
Target: Others
alpha-1,3-Galactosyltransferase (GTB)
Cat.No: T75418
Synonym:
Target: Others
Purine phosphoribosyltransferase-IN-1
Cat.No: T63737
Synonym:
Target: Others
Diacylglycerol acyltransferase inhibitor-1
Cat.No: T11037
Synonym:
Target: Others
Alanine aminotransferase
Cat.No: T78364
Synonym:
Target: Endogenous Metabolite
Catechol O-methyltransferase
Cat.No: T75389
Synonym: COMT
Target: Endogenous Metabolite
alpha-1,4-Galactosyltransferase (LgtC)
Cat.No: T75414
Synonym:
Target: Others
N-acetylglucosamine-1-P uridyltransferase (AGX1)
Cat.No: T78352
Synonym: GlcNAc1pUT
Target: Others
Purine phosphoribosyltransferase-IN-2
Cat.No: T63738
Synonym:
Target: Others
alpha-1,3/4-Fucosyltransferase (α1,3/4FucT)
Cat.No: T75420
Synonym:
Target: Others
alpha-1,3-Galactosyltransferase (a1,3GalT)
Cat.No: T75417
Synonym:
Target: Others
alpha-2,8-Sialyltransferase (CstII)
Cat.No: T75419
Synonym:
Target: Others
alpha-2,6-Sialyltransferase (Pd26ST)
Cat.No: T78353
Synonym:
Target: Others
GlcNAc 1-P uridyltransferase (CjGlmU)
Cat.No: T75399
Synonym:
Target: Others
beta-1,4-Galactosyltransferase (LgtB)
Cat.No: T75413
Synonym:
Target: Others
α-2,3-sialyltransferase-IN-1
Cat.No: T13429
Synonym: Lith-O-Asp analog
Target: Others
Aspartate aminotransferase
Cat.No: T76178
Synonym:
Target:
alpha-2,3-Sialyltransferase (PmST3)
Cat.No: T75421
Synonym:
Target: Others
beta-1,3-Galactosyltransferase (CgtB)
Cat.No: T75415
Synonym:
Target: Others
beta-1, 3-N-Acetylhexaminyltransferase (LgtA)
Cat.No: T75411
Synonym:
Target: Others
GSTO-IN-2
Cat.No: T11504
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
TN6512 Tectol

Transferase; Parasite Metabolism; Microbiology/Virology
Tectol 是从Lippia sidoides 中分离的,对人白血病细胞株 HL60 和 CEM 具有显著的抑制作用。它是法尼基转移酶抑制剂,在人和布氏锥虫的IC50分别为 2.09 和 1.73 μM。它具有抗疟原虫活性,是一种中等活性的生长抑制剂,IC50 为 3.44±0.20μM。
TQ0165 Arglabin

阿格拉宾,(+)-Arglabin

NOD-like Receptor (NLR); Transferase; NOD; Autophagy Autophagy; Immunology/Inflammation; Metabolism; NF-κB
Arglabin ((+)-Arglabin) 是从青蒿中分离出的一种天然产物,是一种 NLRP3 炎性体抑制剂,具有抗动脉粥样硬化和抗癌作用。
T3S0012 coniferyl ferulate

P-gp; GST Membrane transporter/Ion channel; Neuroscience; oxidation-reduction
Coniferyl ferulate 是从川芎中提取的一种天然产物,是强效的谷胱甘肽 S-转移酶抑制剂,强抑制人胎盘型谷胱甘肽 S-转移酶,IC50为 0.3 μM。它还可逆转多药耐药性并下调 P-糖蛋白。
TN1078 Seneciphylline

千里光菲灵碱,千里光非灵

P450; GST Metabolism; oxidation-reduction
Seneciphylline 是一种有毒的吡咯烷核生物碱,存在于千里光植物中。它显著增加了环氧水合酶和谷胱甘肽-S-转移酶的特性,但导致细胞色素 P-450 和相关单加氧酶特性的抑制。
T7995 α-Angelica lactone

α-当归内酯,当归内酯,Alpha-Angelica Lactone

Others; GST Others; oxidation-reduction
α-Angelica lactone 是一种乙烯基亲核试剂,也是一种天然存在的抗癌剂。它可以得到手性的 δ-氨基 γ,γ-二取代丁烯醇内酯羰基衍生物,并在 γ-碳上表现出亲电子俘获。它通过选择性增强谷胱甘肽-S-硫转移酶 (GST) 和 UDP-葡糖苷转移酶 (UGT) 解毒酶发挥强大的化学保护作用。
T3S0541 Curzerene

莪术烯,莪术呋喃烯

Apoptosis; GST Apoptosis; oxidation-reduction
Curzerene, a sesquiterpene compound derived from the rhizome of Curculigo orchioides Gaertn, possesses potent anti-cancer properties. It is known to induce apoptosis in cells[1] and also suppress the expression of glutathione S-transferase A1 (GSTA1) mRNA and protein.
TN3270 (R)-3β-Hydroxy steroid sulfotransferase-IN-11

Others Others
(R)-3β-Hydroxy steroid sulfotransferase-IN-11 在生命科学相关研究中具有广泛的应用。
T3314 Perillyl alcohol

Isocarveol,Perilla alcohol,紫苏醇

Apoptosis; Endogenous Metabolite Apoptosis; Metabolism
Perillyl alcohol (Isocarveol) 是一种单萜,可在不影响正常细胞的情况下诱导肿瘤细胞凋亡。
TJS0405 Lucidin

NSC 30546,芦西定;卢西定,卢西定,亮黄素,Henine

Others Others
Lucidin (NSC-30546) 是茜草中的一种天然成分,可以诱导细菌和哺乳动物细胞的突变。
TN1474 Caulilexin C

板蓝根,1-甲氧基-3-吲哚乙腈

Others; Antifungal Microbiology/Virology; Others
Caulilexin C 是一种来自十字花科植物的植物抗毒素,具有抗真菌活性。
T6758 Anisomycin

茴香霉素,Flagecidin,NSC 76712,Wuningmeisu C

Apoptosis; DNA/RNA Synthesis; Antibacterial; Antibiotic; JNK Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; MAPK; Microbiology/Virology
Anisomycin (Flagecidin) 属于细菌抗生素,是一种蛋白合成抑制剂和一种 JNK 激活剂。Anisomycin 通过抑制肽基转移酶或 80S 核糖体系统来干扰蛋白质和 DNA 的合成。
T5654 Musk ketone

Others Others
Musk ketone 可诱导癌细胞生长抑制和凋亡。它增加谷胱甘肽 S-转移酶的活性,因此可能被证明是有用的癌症化学保护剂。
T3S0218 Thonningianin A

Apoptosis; Others Apoptosis; Others
Thonningianin A 是从非洲草药通宁宁的甲醇提取物中,分离得到的一种鞣花素,具有抗癌和抗氧化性,涉及自由基清除、抗超氧化物形成和金属螯合。
T11680 Isoasatone A

P450 Metabolism
Isoasatone A 是一种具有抗虫作用的天然产物,分离自Heterotropa takaoiM。它作用于细胞色素 P450 单加氧酶和谷胱甘肽转移酶,产生抗S. litura 作用。
T6S0071 Fraxinellone

HIF/HIF Prolyl-Hydroxylase; STAT; PD-1/PD-L1 Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Metabolism; Stem Cells
Fraxinellone 是从白鲜的根皮中分离出来的一种天然产物,是PD-L1抑制剂,可抑制HIF-1α蛋白质合成。它通过靶向 PD-L1,有用于癌症免疫的潜力。
T4848 Mandelic acid

acidomandelico,DL-Mandelic acid,扁桃酸

Others; Endogenous Metabolite; Antibacterial Metabolism; Microbiology/Virology; Others
DL-Mandelic acid (acidomandelico) 是一种 α-羟基羧酸,有抗菌活性,广泛用作医药和精细化学品的中间体,已用于研究尿路感染和阴道滴虫病,还具有较高的精子固定活性和较低的阴道刺激性。
T24412 Lipoxamycin

G 26146,G-26146,G26146,Neoenactin M1

Others Others
Lipoxamycin is an inhibitor of serine palmitoyl-transferase.
TN7377 Methyl ganoderate A

Others Others
Methyl ganoderate A, an inhibitor of Farnesyl protein transferase (FPT) with an IC50 of 38 µM, exhibits potential anticancer effects. Additionally, it inhibits fatty acid amide hydrolase (FAAH), further underscoring its therapeutic potential.
TN7282 Bequinostatin C

Others Others
Glutathione S-Transferase (GST) π class inhibitor is a chemical compound designed to inhibit the action of the π class of GST enzymes.
TN2849 3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid

Antifection Microbiology/Virology
2-O-beta-d-Glucosyloxy-4-methoxybenzenepropanoic acid[3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid] exhibits glutathione S-transferase (GST) inhibitory and antifungal activities.
TN2834 27-p-Coumaroyloxyursolic acid

Others Others
27-trans-p-Coumaroyloxyursolic acid and 27-cis-p-coumaroyloxyursolic acid show potent inhibitory activity in the acyl CoA cholesteryl acyl transferase (ACAT) assay.
TN7281 Bequinostatin A

Others Others
Glutathione S-Transferase (GST) π-class inhibitor acts to inhibit a specific class within the GST enzyme family, targeting the π variant. This compound selectively blocks the activity of this enzyme, which plays a critical role in the detoxification of compounds by catalyzing their conjugation with glutathione.
TN4443 Lipiferolide

Telomerase; Antifection DNA Damage/DNA Repair; Microbiology/Virology
Lipiferolide is an inhibitor of farnesyl protein transferase(FPTase), it inhibits the FPTase activity in a dose-dependent manner, and shows cell growth inhibitory activity against several tumor cells, it possesses cytotoxic activity against KB cells. Liriodenine also has antiplasmodial activity.
T29329 24-Methylenecholesterol

24Methylenecholesterol,24 Methylenecholesterol,Chalinasterol,24-亚甲基胆固醇,Ostreasterol

Acyltransferase Metabolism
24-Methylenecholesterol (24 Methylenecholesterol) 是一种天然海洋甾醇,可刺激人类巨噬细胞中的胆固醇酰基转移酶 (ACAT))。
T11842 Levomecol

Others Others
Levomecol, a broad-spectrum antibiotic derived from Streptomyces venezuelae, comprises Chloramphenicol and Methyluracil. It exerts its bacteriostatic effect by binding to the bacterial ribosome, inhibiting protein synthesis by blocking peptidyl transferase.
TN4345 Jacobine

Others Others
Jacobine induces significant dose-dependent DNA-DNA interstrand cross-linking over the entire range of doses. It was catalyzed by guinea pig hepatic glutathione-S-transferase enzymes in in vitro experiments.
T75696 Ilexoside XLVIII

Others Others
Ilexoside XLVIII为一种三萜皂苷,自苦冬青叶片水提物分离而得,功能为抑制酰基辅酶A胆固醇酰基转移酶(ACAT)。
T11202 Enniatin complex

Others Others
Enniatin complex, a mixture of cyclohexadepsipeptides predominantly derived from various Fusarium species of fungi, exhibits inhibitory effects on enzymes such as acyl-CoA: cholesterol acyl transferase. Furthermore, it has demonstrated the ability to induce apoptosis in multiple cancer cell lines. In addition to these activities, the Enniatin complex possesses ionophoric, antibiotic, and in vitro hypolipidemic properties.
T13053 T-2 Toxin

T-2 Mycotoxin

Apoptosis; ROS; DNA/RNA Synthesis Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation
T-2 Toxin (T-2 Mycotoxin) 是饲料和谷物中的各种镰刀菌种产生的真菌次生代谢产物,具有很强的生殖毒性,可诱发多种心血管毒性。T-2 Toxin 是一种抑制肽基转移酶 (60s ribosomal 亚基) 结合和蛋白质合成的抑制剂,通过ROS诱导的细胞凋亡诱导TM4细胞功能障碍,抑制 DNA 和 RNA 的合成,增加肝脏脂质过氧化物的水平。
T38299 Tunicamycin V

Others Others
Tunicamycin 15:1 is a mixture of tunicamycin structural isomers that contains a 15-carbon N-acyl chain with variable branching patterns.References Tunicamycin 15:1 is a mixture of tunicamycin structural isomers that contains a 15-carbon N-acyl chain with variable branching patterns. References

天然产物

Tectol
Cat.No: TN6512
Synonym:
Target: Transferase, Parasite
Arglabin
Cat.No: TQ0165
Synonym: 阿格拉宾,(+)-Arglabin
Target: NOD-like Receptor (NLR), Transferase, NOD, Autophagy
coniferyl ferulate
Cat.No: T3S0012
Synonym:
Target: P-gp, GST
Seneciphylline
Cat.No: TN1078
Synonym: 千里光菲灵碱,千里光非灵
Target: P450, GST
α-Angelica lactone
Cat.No: T7995
Synonym: α-当归内酯,当归内酯,Alpha-Angelica Lactone
Target: Others, GST
Curzerene
Cat.No: T3S0541
Synonym: 莪术烯,莪术呋喃烯
Target: Apoptosis, GST
(R)-3β-Hydroxy steroid sulfotransferase-IN-11
Cat.No: TN3270
Synonym:
Target: Others
Perillyl alcohol
Cat.No: T3314
Synonym: Isocarveol,Perilla alcohol,紫苏醇
Target: Apoptosis, Endogenous Metabolite
Lucidin
Cat.No: TJS0405
Synonym: NSC 30546,芦西定;卢西定,卢西定,亮黄素,Henine
Target: Others
Caulilexin C
Cat.No: TN1474
Synonym: 板蓝根,1-甲氧基-3-吲哚乙腈
Target: Others, Antifungal
Anisomycin
Cat.No: T6758
Synonym: 茴香霉素,Flagecidin,NSC 76712,Wuningmeisu C
Target: Apoptosis, DNA/RNA Synthesis, Antibacterial, Antibiotic, JNK
Musk ketone
Cat.No: T5654
Synonym:
Target: Others
Thonningianin A
Cat.No: T3S0218
Synonym:
Target: Apoptosis, Others
Isoasatone A
Cat.No: T11680
Synonym:
Target: P450
Fraxinellone
Cat.No: T6S0071
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase, STAT, PD-1/PD-L1
Mandelic acid
Cat.No: T4848
Synonym: acidomandelico,DL-Mandelic acid,扁桃酸
Target: Others, Endogenous Metabolite, Antibacterial
Lipoxamycin
Cat.No: T24412
Synonym: G 26146,G-26146,G26146,Neoenactin M1
Target: Others
Methyl ganoderate A
Cat.No: TN7377
Synonym:
Target: Others
Bequinostatin C
Cat.No: TN7282
Synonym:
Target: Others
3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid
Cat.No: TN2849
Synonym:
Target: Antifection
27-p-Coumaroyloxyursolic acid
Cat.No: TN2834
Synonym:
Target: Others
Bequinostatin A
Cat.No: TN7281
Synonym:
Target: Others
Lipiferolide
Cat.No: TN4443
Synonym:
Target: Telomerase, Antifection
24-Methylenecholesterol
Cat.No: T29329
Synonym: 24Methylenecholesterol,24 Methylenecholesterol,Chalinasterol,24-亚甲基胆固醇,Ostreasterol
Target: Acyltransferase
Levomecol
Cat.No: T11842
Synonym:
Target: Others
Jacobine
Cat.No: TN4345
Synonym:
Target: Others
Ilexoside XLVIII
Cat.No: T75696
Synonym:
Target: Others
Enniatin complex
Cat.No: T11202
Synonym:
Target: Others
T-2 Toxin
Cat.No: T13053
Synonym: T-2 Mycotoxin
Target: Apoptosis, ROS, DNA/RNA Synthesis
Tunicamycin V
Cat.No: T38299
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPH-02151 OXCT1 Protein, Human, Recombinant (His)

OXCT1,Succinyl-CoA:3-ketoacid coenzyme A transferase

Human E. coli
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. OXCT1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 56.1 kDa and the accession number is P55809.
TMPY-00539 GSTA1 Protein, Human, Recombinant (His)

glutathione S-transferase alpha 1,GTH1,GST2,glutath...

Human HEK293 Cells
GSTA1 (Glutathione S-Transferase Alpha 1) is a Protein Coding gene. This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds. Glutathione S-transferases (GSTs) are involved in the detoxification of carcinogens and may be linked to carcinogenesis. As a vital component of GSTs, GSTA1 plays an important role in carcinogenesis. GSTA1 expression may be a target molecule in the early diagnosis and treatment of lung cancer. Human colonic adeno...
TMPH-00164 4'-phosphopantetheinyl transferase ffp Protein, Bacillus subtilis, Recombinant (His & Myc)

4'-phosphopantetheinyl transferase ffp,EC:2.7.8.-,F...

Bacillus subtilis E. coli
May activate the peptidyl carrier protein (PCP) domains of fengycin synthase by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. 4'-phosphopantetheinyl transferase ffp Protein, Bacillus subtilis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 31.0 kDa and the accession number is Q9F4F7.
TMPH-00009 OGT Protein, Human, Recombinant (His & SUMO)

OGT,O-GlcNAc transferase subunit p110,O-linked N-ac...

Human E. coli
OGT Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 62.5 kDa and the accession number is O15294.
TMPH-00569 atoD Protein, E. coli, Recombinant (His & Myc)

AA-CoA transferase subunit alpha,Acetyl-CoA:acetoac...

E. coli E. coli
N/A. atoD Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 30.5 kDa and the accession number is P76458.
TMPY-03450 GSTK1 Protein, Human, Recombinant

glutathione S-transferase κ1,GST,glutathione S-...

Human E. coli
GSTK1 gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. Glutathione S-transferases (GSTs) are a family of enzymes that catalyze a variety of reactions in both eukaryotes and prokaryotes. They catalyze the conjugation of reduced glutathione with potentially toxic, xenobiotic substrates, thus aiding excretion from the body. GSTK1(glutathione S-transferase kappa 1) is localized to the peroxisome and catalyzes the...
TMPY-03338 GSTZ1 Protein, Human, Recombinant (His)

MAI,GSTZ1-1,glutathione S-transferase ζ 1,MAAI,GSTZ...

Human E. coli
GSTZ1 (Glutathione S-Transferase Zeta 1) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. GSTZ1 gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. GSTZ1 is a bifunctional protein that has minimal glutathione-conjugating activity with ethacrynic acid ...
TMPY-00027 GSTT2B Protein, Human, Recombinant (His)

GSTT2P,glutathione S-transferase θ 2B (gene/pseudog...

Human HEK293 Cells
GSTT2B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29 kDa and the accession number is P0CG29.
TMPH-02682 GSTM3 Protein, Mouse, Recombinant (His & Myc)

GST class-mu 3,Gstm3,Glutathione S-transferase Mu 3...

Mouse E. coli
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. GSTM3 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.0 kDa and the accession number is P19639.
TMPH-02666 Fukutin Protein, Mouse, Recombinant (His & Myc)

Fktn,Fukutin,Ribitol-5-phosphate transferase FKTN,F...

Mouse E. coli
Catalyzes the transfer of CDP-ribitol to the distal N-acetylgalactosamine of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). This constitutes the first step in the formation of the ribitol 5-phosphate tandem repeat which links the phosphorylated O-mannosyl trisaccharide to the ligand binding moiety composed of repeats of 3-xylosyl-alpha-1,3-glucuronic acid-b...
TMPH-02429 Fukutin Protein, Cynomolgus, Recombinant (His & Myc)

FKTN,Fukutin,Fukuyama-type congenital muscular dystrophy pro...

Cynomolgus E. coli
Fukutin Protein, Cynomolgus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 58.0 kDa and the accession number is Q60HG0.
TMPY-03332 PRTFDC1 Protein, Human, Recombinant (His)

HHGP,PRTFDC1,phosphoribosyl transferase domain cont...

Human E. coli
PRTFDC1 is a member of the purine/pyrimidine phosphoribosyltransferase family. It can bind GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). The epigenetic silencing of PRTFDC1 by hypermethylation of the CpG island leads to a loss of PRTFDC1 function, which might be involved in squamous cell oral carcinogenesis. PRTFDC1 is a genetic modifier of HPRT-deficiency in the mouse and has important implications for unraveling the molecular etiology of lesch-Nyhan disease(LND). LND is a sever...
TMPH-01396 GSTK1 Protein, Human, Recombinant (GST)

GSTK1,Glutathione S-transferase kappa 1,Glutathione...

Human E. coli
Significant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB). GSTK1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 52.4 kDa and the accession number is Q9Y2Q3.
TMPH-00406 ctfB Protein, Clostridium acetobutylicum, Recombinant (His & Myc)

Butyrate--acetoacetate CoA-transferase subunit B,ct...

Clostridium acetobutylicum E. coli
Involved in solventogenic switch which allows C.acetobutylicum to uptake acid and produce solvents. Acts mainly to detoxify the medium by removing the acetate and butyrate excreted earlier in the fermentation. ctfB Protein, Clostridium acetobutylicum, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 30.6 kDa and the accession number is P23673.
TMPH-00174 MURG Protein, Bacillus subtilis, Recombinant (His)

UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyro...

Bacillus subtilis E. coli
Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II). MURG Protein, Bacillus subtilis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 43.9 kDa and the accession number is P37585.
TMPH-01245 POLM Protein, Human, Recombinant (His & Myc)

DNA-directed DNA/RNA polymerase mu,POLM,Terminal transfe...

Human Baculovirus Insect Cells
Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination. POLM Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 58.8 kDa and the accession number is Q9NP87.
TMPH-00444 GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His & Myc)

GST class-pi,GSTP1,Glutathione S-transferase P

Chinese hamster E. coli
GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His & Myc) is expressed in E. coli.
TMPH-00445 GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His)

Glutathione S-transferase P,GST class-pi,GSTP1

Chinese hamster P. pastoris (Yeast)
GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His) is expressed in Yeast.
TMPH-01399 GSTP1 Protein, Human, Recombinant (His)

GST class-pi,GSTP1,Glutathione S-transferase P,GSTP...

Human P. pastoris (Yeast)
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. GSTP1 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 25.2 kDa and...
TMPJ-00611 SFP Protein, B.subtilis, Recombinant (His)

Surfactin synthase-activating enzyme,sfp,lpa-8,4'-phosphopan...

Bacillus subtilis E. coli
The Bacillus subtilis enzyme Sfp, required for production of the lipoheptapeptide antibiotic surfactin, posttranslationally phosphopantetheinylates a serine residue in each of the seven peptidyl carrier protein domains of the first three subunits (SrfABC) of surfactin synthetase to yield docking sites for amino acid loading and peptide bond formation.
TMPH-03438 CHS1 Protein, S. cerevisiae, Recombinant (His)

CHS1,Chitin-UDP acetyl-glucosaminyl transferase 1,C...

Saccharomyces cerevisiae E. coli
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer. Required for mitotic division septum formation during adverse conditions. CHS1 Protein, S. cerevisiae, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26.6 kDa and the accession number is P08004.
TMPH-02379 arnT Protein, Klebsiella pneumoniae, Recombinant (His)

Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase...

Klebsiella pneumoniae E. coli
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
TMPY-01554 GSTM5 Protein, Human, Recombinant (His)

GSTM5-5,glutathione S-transferase mu 5,GTM5,GSTM5

Human E. coli
GSTM5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 27.9 kDa and the accession number is AAH58881.1.
TMPH-01244 POLM Protein, Human, Recombinant (His)

DNA-directed DNA/RNA polymerase mu,Terminal transferase<...

Human E. coli
Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination. POLM Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 58.8 kDa and the accession number is Q9NP87.
TMPJ-00765 TDT Protein, Human, Recombinant (His)

Terminal transferase,Terminal deoxynucleotidyltr,DN...

Human E. coli
Terminal deoxynucleotidyl transferase (TdT) is a highly conserved vertebrate enzyme that possesses the unique ability to catalyze the random addition of deoxynucleoside 5'-triphosphates onto the 3'-hydroxyl group of a single-stranded DNA. It plays an important role in the generation of immunoglobin and T-cell receptor diversity. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments duri...
TMPY-02223 GSTM2 Protein, Human, Recombinant (His)

GSTM2-2,GTHMUS,glutathione S-transferase mu 2 (musc...

Human E. coli
Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2, and GSTM2, is a cytoplasm protein that belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains one GST C-terminal domain and one GST N-terminal domain. The glutathione S-transferases (GSTs) are a multigene family of enzymes largely involved in the detoxification of chemicals. Eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, si...
TMPH-01398 GSTP1 Protein, Human, Recombinant (E. coli, His)

GSTP1,Glutathione S-transferase P,GSTP1-1,GST class...

Human E. coli
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. GSTP1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted mo...
TMPH-03596 Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (His & Myc)

acpS,4'-phosphopantetheinyl transferase AcpS,Holo-[...

Streptococcus pyogenes Baculovirus Insect Cells
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 17.1 kDa and the accession number is Q48RM7.
TMPH-03597 Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (E. coli, His & Myc)

4'-phosphopantetheinyl transferase AcpS,Holo-[acyl-...

Streptococcus pyogenes E. coli
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.3 kDa and the accession number is Q48RM7.
TMPJ-00499 GSTP1 Protein, Human, Recombinant

GSTP1,GST3,GST class-pi,Glutathione S-transferase P...

Human E. coli
Glutathione S-transferase P (GSTP1) is an enzyme that contains 1 GST C-terminal domain, 1 GST N-terminal domain. GSTP1 belongs to the GST superfamily, the GSTs are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione ...
TMPH-00715 Mcr-1 Protein, E. coli, Recombinant (His & SUMO)

Probable phosphatidylethanolamine transferase Mcr-1...

E. coli E. coli
Mcr-1 Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 56.7 kDa and the accession number is A0A0R6L508.
TMPH-00085 SIZ1 Protein, Arabidopsis thaliana, Recombinant (His)

E3 SUMO-protein ligase SIZ1,SIZ1,E3 SUMO-protein transfe...

Arabidopsis thaliana E. coli
E3 SUMO protein ligase involved in regulation processes. Mediates SUMO/ attachment to PHR1, a MYB transcriptional activator controlling the phosphate deficiency responses. Functions as an upstream negative regulator of salicylic acid (SA) accumulation and subsequent SA-mediated systemic acquired resistance (SAR) signaling. Probably not involved in jasmonic acid (JA)-mediated defense response. Participates in abiotic stress-induced sumoylation. Controls heat shock-induced SUMO1 and SUMO2 conjugat...
TMPH-00017 acpS Protein, Acholeplasma laidlawii, Recombinant (His & Myc)

Holo-ACP synthase,Holo-[acyl-carrier-protein] synthase,acpS,...

Acholeplasma laidlawii E. coli
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. acpS Protein, Acholeplasma laidlawii, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 20.9 kDa and the accession number is A9NHV3.
TMPJ-01302 ACAT2 Protein, Human, Recombinant (His)

ACTL,Acetyl-CoA transferase-like protein,Acetyl-CoA...

Human E. coli
ACAT2 is a cytoplasmic enzyme which belongs to the thiolase family. ACAT2 takes part in lipid metabolism, lipoprotein assembly, catalyzing cholesterol esterification in mammalian cells. It is responsible for the synthesis of cholesteryl esters which are part of lipoproteins containing apoB. ACAT2 deficiency contributes to severe mental retardation and hypotonus.
TMPK-01001 RNF43 Protein, Mouse, Recombinant (hFc)

Rnf43,RING finger protein 43,RING-type E3 ubiquitin tran...

Mouse HEK293 Cells
RNF43 (E3 ubiquitin-protein ligase RNF43 or RING-type E3 ubiquitin transferase RNF43) functions as a tumor suppressor, by exerting a predominant negative feedback mechanism in the Wnt/β-catenin signaling pathway. RNF43 inhibits Wnt/beta-catenin signaling by ubiquitinating Frizzled receptor and targeting it to the lysosomal pathway for degradation.
TMPH-01397 LANCL1 Protein, Human, Recombinant (His & Myc)

LANCL1,40 kDa erythrocyte membrane protein,Glutathione S-

Human E. coli
Functions as glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during normal postnatal development and in response to oxidative stresses probably through GSH antioxidant defense mechanism. May play a role in EPS8 signaling. Binds glutathione. LANCL1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc...
TMPH-03306 GSTP1 Protein, Rat, Recombinant (His)

Chain 7,Glutathione S-transferase P,GST 7-7,GST cla...

Rat E. coli
GSTP1 Protein, Rat, Recombinant (His) is expressed in E. coli.
TMPH-03305 GSTA1 Protein, Rat, Recombinant (His & SUMO)

Androst-5-ene-3,17-dione isomerase,GST 1-1,13-hydroperoxyoct...

Rat E. coli
GSTA1 Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-03448 EHT1 Protein, S. cerevisiae, Recombinant (His)

EHT1,Ethanol hexanoyl transferase 1,Alcohol O-acety...

Saccharomyces cerevisiae E. coli
Displays enzymatic activity both for medium-chain fatty acid (MCFA) ethyl ester synthesis and hydrolysis (esterase activity). MCFA are toxic for yeast and this enzyme could thus be involved in their detoxification by esterification. EHT1 Protein, S. cerevisiae, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 57.3 kDa and the accession number is P38295.
TMPH-02683 GSTP1 Protein, Mouse, Recombinant (His & SUMO)

Gstp1,GST-piB,GST class-pi,Preadipocyte growth factor,GST YF...

Mouse E. coli
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.
TMPH-02247 TRIM5 Protein, Human, Recombinant (B2M & His)

Tripartite motif-containing protein 5,TRIM5,RING finger prot...

Human E. coli
TRIM5 Protein, Human, Recombinant (B2M & His) is expressed in E. coli expression system with N-6XHis-B2M tag. The predicted molecular weight is 70.3 kDa and the accession number is Q9C035.
TMPH-03391 TRIM2 Protein, Rat, Recombinant (His)

Trim2,Tripartite motif-containing protein 2,E3 ubiquitin-pro...

Rat E. coli
E3 ubiquitin-protein ligase that mediates the ubiquitination of phosphorylated BCL2L11. Also mediates the UBE2D1-dependent ubiquitination of NEFL. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance. TRIM2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 85.5 kDa and the accession number is D3ZQG6.
TMPH-02628 Cathepsin C Protein, Mouse, Recombinant (His & Myc)

Dipeptidyl transferase,Dipeptidyl peptidase I,Cathe...

Mouse E. coli
Thiol protease. Has dipeptidylpeptidase activity. Can act as both an exopeptidase and endopeptidase. Can degrade glucagon. Plays a role in the generation of cytotoxic lymphocyte effector function.
TMPH-01261 NEDD4L Protein, Human, Recombinant (GST)

NEDD4L,HECT-type E3 ubiquitin transferase NED4L,Ned...

Human E. coli
NEDD4L Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 138.5 kDa and the accession number is Q96PU5.
TMPH-01267 RNF13 Protein, Human, Recombinant (His & Myc)

RING finger protein 8,RNF8,E3 ubiquitin-protein ligase RNF8,...

Human E. coli
E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of hist...
TMPH-01272 TRIM9 Protein, Human, Recombinant (His & SUMO)

RING finger protein 91,RING-type E3 ubiquitin transferas...

Human E. coli
E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions and may also participate in the formation or breakdown of abnormal inclusions in neurodegenerative disorders. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation.
TMPH-01268 SIAH1 Protein, Human, Recombinant (GST)

SIAH1,RING-type E3 ubiquitin transferase SIAH1,Siah...

Human E. coli
SIAH1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 61.6 kDa and the accession number is Q8IUQ4.
TMPH-01274 ZNRF3 Protein, Human, Recombinant (His & SUMO)

RING-type E3 ubiquitin transferase ZNRF3,E3 ubiquit...

Human E. coli
E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone. Along with RSPO2 and RNF43, constitutes a master switch that governs ...
TMPJ-01115 GALNT3 Protein, Human, Recombinant (His)

GalNAc-T3,Polypeptide N-acetylgalactosaminyltransferase<...

Human HEK293 Cells
Polypeptide N-acetylgalactosaminyltransferase 3(GALNT3) belongs to the glycosyltransferase 2 family and galNAc-T subfamily. It expressed in organs that contain secretory epithelial glands and it highly expressed in pancreas, skin, kidney and testis. There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Ga...
TMPH-01904 HERC1 Protein, Human, Recombinant (His & Myc)

HECT domain and RCC1-like domain-containing protein 1,p619,H...

Human E. coli
HERC1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
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重组蛋白

OXCT1 Protein, Human, Recombinant (His)
Cat.No: TMPH-02151
Species: Human
Expression System: E. coli
GSTA1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00539
Species: Human
Expression System: HEK293 Cells
4'-phosphopantetheinyl transferase ffp Protein, Bacillus subtilis, Recombinant (His & Myc)
Cat.No: TMPH-00164
Species: Bacillus subtilis
Expression System: E. coli
OGT Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-00009
Species: Human
Expression System: E. coli
atoD Protein, E. coli, Recombinant (His & Myc)
Cat.No: TMPH-00569
Species: E. coli
Expression System: E. coli
GSTK1 Protein, Human, Recombinant
Cat.No: TMPY-03450
Species: Human
Expression System: E. coli
GSTZ1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03338
Species: Human
Expression System: E. coli
GSTT2B Protein, Human, Recombinant (His)
Cat.No: TMPY-00027
Species: Human
Expression System: HEK293 Cells
GSTM3 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02682
Species: Mouse
Expression System: E. coli
Fukutin Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02666
Species: Mouse
Expression System: E. coli
Fukutin Protein, Cynomolgus, Recombinant (His & Myc)
Cat.No: TMPH-02429
Species: Cynomolgus
Expression System: E. coli
PRTFDC1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03332
Species: Human
Expression System: E. coli
GSTK1 Protein, Human, Recombinant (GST)
Cat.No: TMPH-01396
Species: Human
Expression System: E. coli
ctfB Protein, Clostridium acetobutylicum, Recombinant (His & Myc)
Cat.No: TMPH-00406
Species: Clostridium acetobutylicum
Expression System: E. coli
MURG Protein, Bacillus subtilis, Recombinant (His)
Cat.No: TMPH-00174
Species: Bacillus subtilis
Expression System: E. coli
POLM Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01245
Species: Human
Expression System: Baculovirus Insect Cells
GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His & Myc)
Cat.No: TMPH-00444
Species: Chinese hamster
Expression System: E. coli
GSTP1 Protein, Cricetulus longicaudatus, Recombinant (His)
Cat.No: TMPH-00445
Species: Chinese hamster
Expression System: P. pastoris (Yeast)
GSTP1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01399
Species: Human
Expression System: P. pastoris (Yeast)
SFP Protein, B.subtilis, Recombinant (His)
Cat.No: TMPJ-00611
Species: Bacillus subtilis
Expression System: E. coli
CHS1 Protein, S. cerevisiae, Recombinant (His)
Cat.No: TMPH-03438
Species: Saccharomyces cerevisiae
Expression System: E. coli
arnT Protein, Klebsiella pneumoniae, Recombinant (His)
Cat.No: TMPH-02379
Species: Klebsiella pneumoniae
Expression System: E. coli
GSTM5 Protein, Human, Recombinant (His)
Cat.No: TMPY-01554
Species: Human
Expression System: E. coli
POLM Protein, Human, Recombinant (His)
Cat.No: TMPH-01244
Species: Human
Expression System: E. coli
TDT Protein, Human, Recombinant (His)
Cat.No: TMPJ-00765
Species: Human
Expression System: E. coli
GSTM2 Protein, Human, Recombinant (His)
Cat.No: TMPY-02223
Species: Human
Expression System: E. coli
GSTP1 Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-01398
Species: Human
Expression System: E. coli
Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (His & Myc)
Cat.No: TMPH-03596
Species: Streptococcus pyogenes
Expression System: Baculovirus Insect Cells
Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (E. coli, His & Myc)
Cat.No: TMPH-03597
Species: Streptococcus pyogenes
Expression System: E. coli
GSTP1 Protein, Human, Recombinant
Cat.No: TMPJ-00499
Species: Human
Expression System: E. coli
Mcr-1 Protein, E. coli, Recombinant (His & SUMO)
Cat.No: TMPH-00715
Species: E. coli
Expression System: E. coli
SIZ1 Protein, Arabidopsis thaliana, Recombinant (His)
Cat.No: TMPH-00085
Species: Arabidopsis thaliana
Expression System: E. coli
acpS Protein, Acholeplasma laidlawii, Recombinant (His & Myc)
Cat.No: TMPH-00017
Species: Acholeplasma laidlawii
Expression System: E. coli
ACAT2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01302
Species: Human
Expression System: E. coli
RNF43 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-01001
Species: Mouse
Expression System: HEK293 Cells
LANCL1 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01397
Species: Human
Expression System: E. coli
GSTP1 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03306
Species: Rat
Expression System: E. coli
GSTA1 Protein, Rat, Recombinant (His & SUMO)
Cat.No: TMPH-03305
Species: Rat
Expression System: E. coli
EHT1 Protein, S. cerevisiae, Recombinant (His)
Cat.No: TMPH-03448
Species: Saccharomyces cerevisiae
Expression System: E. coli
GSTP1 Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02683
Species: Mouse
Expression System: E. coli
TRIM5 Protein, Human, Recombinant (B2M & His)
Cat.No: TMPH-02247
Species: Human
Expression System: E. coli
TRIM2 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03391
Species: Rat
Expression System: E. coli
Cathepsin C Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02628
Species: Mouse
Expression System: E. coli
NEDD4L Protein, Human, Recombinant (GST)
Cat.No: TMPH-01261
Species: Human
Expression System: E. coli
RNF13 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01267
Species: Human
Expression System: E. coli
TRIM9 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01272
Species: Human
Expression System: E. coli
SIAH1 Protein, Human, Recombinant (GST)
Cat.No: TMPH-01268
Species: Human
Expression System: E. coli
ZNRF3 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01274
Species: Human
Expression System: E. coli
GALNT3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01115
Species: Human
Expression System: HEK293 Cells
HERC1 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01904
Species: Human
Expression System: E. coli
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Cat. No. Product Name Target Signaling Pathways
TMID-0056 (±)-Mandelic-2,3,4,5,6-d5 Acid

(±)-Mandelic-2,3,4,5,6-d5 Acid 是 (±)-Mandelic Acid 的氘代化合物。(±)-Mandelic Acid 的 CAS 号为 90-64-2。DL-Mandelic acid 是一种 α-羟基羧酸,有抗菌活性,广泛用作医药和精细化学品的中间体,已用于研究尿路感染和阴道滴虫病,还具有较高的精子固定活性和较低的阴道刺激性。

同位素标记化合物

(±)-Mandelic-2,3,4,5,6-d5 Acid
Cat.No: TMID-0056
Synonym:
Target:
TargetMol Loading
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