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Phoxim(辛硫磷)是一种有机磷酸酯类杀虫剂,抑制昆虫神经系统中的乙酰胆碱酯酶(AchE)活性。在兽医学中用于治疗外寄生螨虫。对水生生物具有毒性,可能影响鱼类肝脏微粒体中细胞色素P450酶(CYP1A)的活性及其表达水平。此外,亚致死剂量的辛硫磷也会影响桑粉虱成虫的解毒酶活性,如谷胱甘肽S-转移酶(GST)、羧酸酯酶(CarE)和乙酰胆碱酯酶(AchE)的活性变化。
Phoxim(辛硫磷)是一种有机磷酸酯类杀虫剂,抑制昆虫神经系统中的乙酰胆碱酯酶(AchE)活性。在兽医学中用于治疗外寄生螨虫。对水生生物具有毒性,可能影响鱼类肝脏微粒体中细胞色素P450酶(CYP1A)的活性及其表达水平。此外,亚致死剂量的辛硫磷也会影响桑粉虱成虫的解毒酶活性,如谷胱甘肽S-转移酶(GST)、羧酸酯酶(CarE)和乙酰胆碱酯酶(AchE)的活性变化。
产品描述 | Phoxim is an organophosphate insecticide that inhibits acetylcholinesterase (AchE) activity in the nervous system of insects. It is used in veterinary medicine for the treatment of ectoparasitic mites. It is toxic to aquatic organisms and may affect cytochrome P450 enzyme (CYP1A) activity and its expression levels in fish liver microsomes. In addition, sub-lethal doses of phoxim affected detoxification enzyme activities of adult mulberry whitefly, such as changes in the activities of glutathione S-transferase (GST), carboxylesterase (CarE) and acetylcholinesterase (AchE). |
别名 | 辛硫磷 |
分子量 | 298.3 |
分子式 | C12H15N2O3PS |
CAS No. | 14816-18-3 |
Smiles | N#CC(=NOP(=S)(OCC)OCC)C=1C=CC=CC1 |
密度 | 1.21 g/cm3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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