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Search Results for " reductase "

Targets Recommended: Reductase HMG-CoA Reductase Glutathione reductase Others

369

抑制剂 & 化合物

78

天然产物

1

化合物库

107

重组蛋白

18

同位素标记化合物

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Cat. No.	Product Name
L2510	脂代谢化合物库		492 compounds
	492 个脂代谢相关的化合物集合，可用于高通量和高内涵筛选；

化合物库

脂代谢化合物库

Cat.No: L2510

Compounds: 492

Cat. No.	Product Name	Target	Signaling Pathways
TP1604L	Thioredoxin reductase peptide acetate Thioredoxin reductase peptide acetate(950890-23-0 free base)	Others	Others
	Thioredoxin reductase peptide acetate(950890-23-0 free base) 对应于硫氧还蛋白还原酶 (TrxR) 中的 53–67 位残基，用于硫氧还蛋白还原酶研究。哺乳动物硫氧还蛋白还原酶 (TR) 催化硫氧还蛋白 (Trx) 的氧化还原活性二硫键的还原，并且在结构和谷胱甘肽还原酶的作用机制，除了 C 末端的 16 个氨基酸延伸部分含有一个罕见的连位硒硫键。
T14175	Aldose reductase-IN-1 AT-001,Caficrestat	Others; Reductase	Endocrinology/Hormones; Metabolism; Others
	Aldose reductase-IN-1 (AT-001)是醛糖还原酶的高效抑制剂, IC50=为28.9 pM。
T78342	Glutathione reductase EC 1.6.4.2	Others	Others
	Glutathione reductase (EC 1.6.4.2) 是维持还原型谷胱甘肽供应的还原酶。
TP1604	Thioredoxin reductase peptide
	Thioredoxin reductase peptide corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research.Mammalian thioredoxin reductase (TR) catalyzes the reduction of the redox-active disulfide bond of thioredoxin (Trx) and is
TP1375	Thioredoxin reductase peptide TFA
	Thioredoxin reductase peptide TFA corresponds to residues 53-67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research..
T10636	5α-reductase-IN-1	Others	Others
	5α-reductase-IN-1 is a potent inhibitor of the enzyme 5α-reductase. This compound is primarily employed in research studies to investigate its potential efficacy in treating patterned alopecia. It is commonly used in combination with minoxidil, a well-known treatment for hair loss.
T80057	Cytochrome P450 reductase	Others	Others
	Cytochrome P450reductase，一种NADPH-细胞色素还原酶，发挥作用于促进芳香酶构象，以最适合底物结合。
T61555	Aldose reductase-IN-6	Others	Others
	Aldose reductase-IN-6 (Compound 3) is a competitive inhibitor of aldose reductase (AR), possessing an IC50 of 3.164 μM and a Ki of 0.018 μM. Notably, Aldose reductase-IN-6 demonstrates no cytotoxicity toward normal cells [1].
T62951	Aldose reductase-IN-2	Others	Others
	Aldose reductase-IN-2 (Compound 5f) 是一种醛糖还原酶 (AR) 的有效抑制剂，具有抗氧化作用。Aldose reductase-IN-2 是一种很有前途的抗糖尿病并发症药物。
T61957	Aldose reductase-IN-3	Others	Others
	Aldose reductase-IN-3 (Compound 5) 是有效的、中等选择性的醛糖还原酶 (AR) 抑制剂（IC50= 3.99 μM）。醛糖还原酶是参与各种炎症性疾病 (包括败血症) 的分子靶标。Aldose reductase-IN-3在脓毒症中具有研究的潜力。
T60601	Aldose reductase-IN-4	Others	Others
	Aldose reductase-IN-4 (comund IIc) 是一种醛糖还原酶的抑制剂，其对ALR1和ALR2的IC50值分别为 11.70 μM 和 0.98 μM。
T60897	Aldose reductase-IN-5	Others	Others
	Aldose reductase-IN-5 是一种醛糖还原酶（ALR2）抑制剂，可增强抑制性兴奋性和抗氧化能力的组合，从而延缓糖尿病并发症的进程。
T22757	EBPC	Reductase	Endocrinology/Hormones; Metabolism
	EBPC 是醛糖还原酶的选择性抑制剂，其IC50= 47 nM。
T79520	HMG-CoA Reductase-IN-1	Others	Others
	HMG-CoA Reductase-IN-1是一种HMG-CoA还原酶抑制剂，显示出高HMGR抑制活性及OATP1B1亲和力，具有pIC50值8.54和pKm值1.98。该化合物适用于高胆固醇血症的研究。
T16910	Sorbinil	Reductase	Endocrinology/Hormones; Metabolism
	Sorbinil 是一种醛糖还原酶抑制剂，在糖尿病及其并发症方面发挥治疗作用。
T23403	Sulindac sulfone	Reductase; COX	Endocrinology/Hormones; Immunology/Inflammation; Metabolism; Neuroscience
	Sulindac sulfone 是非甾体抗炎药舒林酸 (sulindac) 的代谢物。它是醛糖还原酶的抑制剂 (IC50 =367 nM)。
T14342	Atorvastatin lactone	HMG-CoA Reductase	Metabolism
	Atorvastatin lactone 是一种 Atorvastatin 的前药。其中 Atorvastatin 是口服具有活力的 3- 羟基 -3- 甲基戊二酰辅酶 A 还原酶抑制剂。
T6901	N6022	GSNOR	Metabolism
	N6022 是选择性可逆的S-Nitrosoglutathione reductase 抑制剂，IC50=8 nM。
T0488	Finasteride 非那雄胺,MK-906	Reductase	Endocrinology/Hormones; Metabolism
	Finasteride (MK-906) 是 5α-还原酶的竞争性抑制剂，对 II 型 5α-还原酶的IC50为 4.2 nM，对 II 型 5α-还原酶的亲和力是 I 型酶的 100 倍。它可用于研究前列腺增生和雄激素性脱发。
T10393	AT-007	Reductase	Endocrinology/Hormones; Metabolism
	AT-007 是口服有效的，中枢神经系统渗透性醛糖还原酶的高效抑制剂， IC50为 100 pM。在 GALT 缺失大鼠中，它降低了有毒的半乳糖醇水平并预防了疾病并发症。
T1499	Dutasteride GG 745,Avodart,度他雄胺,GI 198745	Apoptosis; Reductase	Apoptosis; Endocrinology/Hormones; Metabolism
	Dutasteride (GI 198745) 是一种 5α 还原酶同工酶抑制剂，还可能因其结构域 DHT 相似对雄激素受体产生脱靶效应。
T5481	TRi-1	Others	Others
	TRi-1 是不可逆的胞质硫氧还蛋白还原酶1 的特异性抑制剂(IC50:12 nM)。它有抗肿瘤作用，且线粒体毒性很小。
T17114	Tolrestat 托瑞司他,AY-27773	Reductase	Endocrinology/Hormones; Metabolism
	Tolrestat (AY-27773) 是一种口服有效的醛糖还原酶抑制剂 (IC50 = 35 nM)。
T36692	Fanotaprim	DHFR	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Fanotaprim 是二氢叶酸还原酶的有效抑制剂，抑制 tgDHFR (Toxoplasma gondiiDHFR) 和 hDHFR (human DHFR)的 IC50分别为 1.57 和 308 nM。Fanotaprim 在研究弓形虫病方面具有价值。
T10339	Antitrypanosomal agent 1	Parasite	Microbiology/Virology
	Antitrypanosomal agent 1 是一种有效的选择性锥虫硫酮还原酶抑制剂，IC50为 3.3 μM。它抑制谷胱甘肽还原酶，IC50为 64.8 μM，抑制布氏锥虫，EC50为 1 μM。
T2013	Ponalrestat	Reductase	Endocrinology/Hormones; Metabolism
	Ponalrestat 是一种口服有效的，选择性的和非竞争性的醛糖还原酶抑制剂，对 ALR2选择性选择性较高，Ki 为 7.7 nM，对 ALR1 的选择性较弱，Ki 为 60 μM。Ponalrestat 抑制葡萄糖向山梨糖醇的转化。
T14362	AY 9944	Others	Others
	AY 9944 是特异性的胆固醇生物合成抑制剂。它抑制 7- 脱氢胆固醇 Δ7- 还原酶 (IC50:13 nM)，导致胆固醇不足和 7DHC 积累。在高剂量下，它可在培养的胚胎中抑制固醇 Δ7-Δ8 异构酶，造成胆固醇 8-en-3β-ol 的积累。
T5195	Alrestatin 阿瑞司他丁,AY-22284	Reductase	Endocrinology/Hormones; Metabolism
	Alrestatin (AY-22284) 是醛糖还原酶的特异性抑制剂，能够在体外减弱大鼠血管平滑肌中葡萄糖诱导的血管紧张素 II 的产生。
T8452	Dantrolene	Others	Others
	Dantrolene 是一种肌肉松弛剂，是人红细胞谷胱甘肽还原酶的非竞争性抑制剂，其Ki 和IC50值分别为 111.6 μM 和 52.3 μM。它是兰尼碱受体拮抗剂及Ca2+信号稳定剂。它可用于研究恶性高热、亨廷顿病、肌肉痉挛和其他神经阻滞剂恶性综合征。
T1487	Fluvastatin sodium XU 62320 sodium,XU-62-320,氟伐他汀钠,Fluvastatin sodium salt	Ferroptosis; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Fluvastatin sodium (Fluvastatin sodium salt) salt 是羟甲基戊二酰辅酶 A 还原酶的竞争性抑制剂，IC50为 8 nM。它通过依赖 Nrf2 的抗氧化通路保护血管平滑肌细胞免受氧化应激，是一种常用的降胆固醇剂。
T1458	Epalrestat ONO2235,依帕斯他,依帕司他	Reductase	Endocrinology/Hormones; Metabolism
	Epalrestat (ONO2235) 是醛糖还原酶抑制剂，在长期治疗中具有良好的耐受性。它可以有效改善糖尿病神经病变的相关症状并延缓疾病的进展，特别是在微血管病变有限且血糖控制良好的患者中。
T6450	Clinofibrate 克利贝特,S-8527,Lipoclin	HMG-CoA Reductase; Autophagy	Autophagy; Metabolism
	Clinofibrate (Lipoclin) 是一种降脂剂，可抑制羟甲基戊二酰辅酶 A 还原酶。它用于控制血液中的高胆固醇和甘油三酯水平。
T22229	Acid Yellow 36 Metanil Yellow,酸性黄36	Others	Others
	Acid Yellow 36 (Metanil Yellow) 是一种偶氮染料和 pH 指示剂，当 pH 值从 1.2 到 2.3 时，发生由红色到黄色的颜色转变。它是 P-450 特异性同工酶和胞浆酶的双功能诱导剂，可用于皮革、造纸和纺织工业。
T38684	AKR1C3-IN-4 AKR1C3-IN-4	NADPH	Metabolism
	AKR1C3-IN-4 是醛酮还原酶 1C3 (AKR1C3) 选择性抑制剂，IC50为 0.56 μM。它在去势抵抗性前列腺癌中有研究的价值。
T0297	Clofarabine Clofarex,氯法拉滨,克罗拉滨,Evoltra,Clolar	Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis; Autophagy	Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Clofarabine (Clofarex) 是一种核糖核苷酸还原酶抑制剂，IC50值为65 nM。它是核苷类似物，可用于癌症研究。
T8003	Methotrexate disodium	Apoptosis; Dehydrogenase; DNA/RNA Synthesis; Antifolate; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Methotrexate disodium 是一种叶酸类似物代谢抑制剂，具有免疫抑制剂和抗肿瘤特性，用于类风湿关节炎和研究多种癌症。
T14864	Caracemide NSC-253272,卡醋胺	Others; DNA/RNA Synthesis; Antibacterial	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	Caracemide (NSC-253272) 抑制大肠杆菌的核糖核苷酸还原酶。 Caracemide 可用于抗癌研究。
T6994	SR12813 SR-12813,SR 12813,GW 485801	HMG-CoA Reductase; Autophagy	Autophagy; Metabolism
	SR12813 (GW 485801) 是一种人孕烷X 受体激动剂，还是一种 3-羟基-3-甲基-戊二酰辅酶 A 还原酶抑制剂，IC50值为 0.85 μM。
T35317	Zopolrestat CP 73850,CP73850,CP-73850,唑泊司他,Zopolrestatum	Reductase	Endocrinology/Hormones; Metabolism
	Zopolrestat (CP 73850) 是口服有效的醛糖还原酶抑制剂，IC50为3.1 nM。Zopolrestat (CP 73850) 在糖尿病并发症方面有研究的价值。
T3693	DHFR-IN-3 7-bromoquinazoline-2,4-diamine,7-溴-2,4-二氨基喹唑啉	Others; DHFR	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	DHFR-IN-3 (7-bromoquinazoline-2,4-diamine) 是一种二氢叶酸还原酶 (DHFR) 抑制剂。
T3157	COH29 RNR Inhibitor COH29	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	COH29 (RNR Inhibitor COH29) 是一种口服可用的芳香族取代噻唑，是人类核糖核苷酸还原酶 (RNR) 的抑制剂，具有潜在的抗肿瘤活性。它抑制核糖核苷酸还原酶的IC50为 16 μM。
T12092	Monacolin J Antibiotic MB 530A,Lovastatin diol lactone,辛伐他汀内酯二醇	HMG-CoA Reductase; Autophagy	Autophagy; Metabolism
	Monacolin J (Antibiotic MB 530A) 是一种胆固醇生物合成抑制剂，抑制 HMG-CoA 还原酶的活性。
T15568	Imirestat Alcon 1576,AL 1576,咪瑞司他,HOE 843	Reductase	Endocrinology/Hormones; Metabolism
	Imirestat (HOE 843) 是=aldose reductase 的抑制剂，在糖尿病中有研究价值。
T6120	Pralatrexate Folotyn,10-炔丙基-10-去氮杂氨基蝶呤,10-Propargyl-10-deazaaminopterin,普拉曲沙	Apoptosis; DHFR; Antifolate; TAM Receptor	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Tyrosine Kinase/Adaptors
	Pralatrexate (10-Propargyl-10-deazaaminopterin) 是一种抗叶酸剂，也是二氢叶酸还原酶抑制剂，Ki 值为 13.4 pM。它具有抗肿瘤活性，可研究复发/难治性 T 细胞淋巴瘤。它是叶酰聚谷氨酸合成酶的底物，具有改善的细胞摄取和保留能力。
T3116	Atorvastatin hemicalcium salt Lipitor,Atorvastatin hemicalcium,Atorvastatin Calcium,CI-981,阿托伐他汀钙,Sortis	Ferroptosis; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Atorvastatin hemicalcium salt (Atorvastatin Calcium) 是一种口服有效的 HMG-CoA 还原酶抑制剂，可用作降低胆固醇的药物。它抑制人 SV-SMC 增殖和侵袭，IC50分别为 0.39 μM 和 2.39 μM。
T1676	Rosuvastatin 罗伐他汀,ZD 4522,瑞舒伐他汀	Potassium Channel; HMG-CoA Reductase; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism
	Rosuvastatin (ZD 4522) 是一种抗血脂药，可竞争性抑制羟甲基戊二酰辅酶 A 还原酶，用于降低血浆胆固醇水平和预防心血管疾病。它降低低密度脂蛋白胆固醇、甘油三酯和 C-反应蛋白水平。它阻断人类醚-a-go-go 相关基因电流，IC50为 195 nM，延迟心脏复极化，延长动作电位持续时间和校正 QT 间期间隔。
T2534	Pitavastatin calcium P-872441,nisvastatin,itavastatin,Pitavastatin hemicalcium,匹伐他汀钙,NK-104	Apoptosis; Mitophagy; Endogenous Metabolite; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Pitavastatin calcium (NK-104) 是一种羟甲基戊二酰-CoA 还原酶抑制剂。它在 HepG2 细胞中抑制乙酸合成胆固醇的IC50为 5.8 nM。它是高效的肝细胞低密度脂蛋白胆固醇受体诱导剂。具有抗癌活性。
T1510	Rosuvastatin calcium ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium,瑞舒伐他汀钙	Potassium Channel; HMG-CoA Reductase; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism
	Rosuvastatin calcium (ZD4522) 是肝羟甲基戊二酰辅酶 A 还原酶的选择性和竞争性抑制剂，具有抗血脂活性。它降低成熟 hERG 的表达以及热休克蛋白 70 与 hERG 蛋白的相互作用，还降低低密度脂蛋白胆固醇、甘油三酯和 C-反应蛋白水平。它阻断人类醚-a-go-go 相关基因电流，延迟心脏复极化，来延长动作电位持续时间和校正 QT 间期间隔。
T1485	Methotrexate NCI-C04671,WR19039,Amethopterin,甲氨蝶呤,CL14377	Apoptosis; Dehydrogenase; DNA/RNA Synthesis; Antifolate; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Methotrexate (WR19039) 是一种叶酸类似物，一种二氢叶酸还原酶 DHFR 的抑制剂。Methotrexate 具有抗代谢、抗肿瘤和免疫抑制等活性，常用于类风湿关节炎和多种肿瘤的研究。
T20765	Atorvastatin 阿托伐他汀,阿伐他汀	HMG-CoA Reductase; Autophagy	Autophagy; Metabolism
	Atorvastatin 是一种具有口服活性的 HMG-CoA 还原酶抑制剂，通过激活肝细胞色素p450加快代谢，具有有效降低血脂的能力。Atorvastatin 以 IC50 值分别为 0.39 μM 和 2.39 μM 来抑制人 SV-SMC 细胞的增殖和侵袭。Atorvastatin 与氯吡格雷同时服用两种可能会导致患者血栓事件增加。

化合物

Thioredoxin reductase peptide acetate

Cat.No: TP1604L

Synonym: Thioredoxin reductase peptide acetate(950890-23-0 free base)

Target: Others

Aldose reductase-IN-1

Cat.No: T14175

Synonym: AT-001,Caficrestat

Target: Others, Reductase

Glutathione reductase

Cat.No: T78342

Synonym: EC 1.6.4.2

Target: Others

Thioredoxin reductase peptide

Cat.No: TP1604

Thioredoxin reductase peptide TFA

Cat.No: TP1375

5α-reductase-IN-1

Cat.No: T10636

Target: Others

Cytochrome P450 reductase

Cat.No: T80057

Target: Others

Aldose reductase-IN-6

Cat.No: T61555

Target: Others

Aldose reductase-IN-2

Cat.No: T62951

Target: Others

Aldose reductase-IN-3

Cat.No: T61957

Target: Others

Aldose reductase-IN-4

Cat.No: T60601

Target: Others

Aldose reductase-IN-5

Cat.No: T60897

Target: Others

Cat.No: T22757

Target: Reductase

HMG-CoA Reductase-IN-1

Cat.No: T79520

Target: Others

Cat.No: T16910

Target: Reductase

Sulindac sulfone

Cat.No: T23403

Target: Reductase, COX

Atorvastatin lactone

Cat.No: T14342

Target: HMG-CoA Reductase

Cat.No: T6901

Target: GSNOR

Cat.No: T0488

Synonym: 非那雄胺,MK-906

Target: Reductase

Cat.No: T10393

Target: Reductase

Cat.No: T1499

Synonym: GG 745,Avodart,度他雄胺,GI 198745

Target: Apoptosis, Reductase

Cat.No: T5481

Target: Others

Cat.No: T17114

Synonym: 托瑞司他,AY-27773

Target: Reductase

Cat.No: T36692

Target: DHFR

Antitrypanosomal agent 1

Cat.No: T10339

Target: Parasite

Cat.No: T2013

Target: Reductase

Cat.No: T14362

Target: Others

Cat.No: T5195

Synonym: 阿瑞司他丁,AY-22284

Target: Reductase

Cat.No: T8452

Target: Others

Fluvastatin sodium

Cat.No: T1487

Synonym: XU 62320 sodium,XU-62-320,氟伐他汀钠,Fluvastatin sodium salt

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Cat.No: T1458

Synonym: ONO2235,依帕斯他,依帕司他

Target: Reductase

Cat.No: T6450

Synonym: 克利贝特,S-8527,Lipoclin

Target: HMG-CoA Reductase, Autophagy

Cat.No: T22229

Synonym: Metanil Yellow,酸性黄36

Target: Others

Cat.No: T38684

Synonym: AKR1C3-IN-4

Target: NADPH

Cat.No: T0297

Synonym: Clofarex,氯法拉滨,克罗拉滨,Evoltra,Clolar

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Autophagy

Methotrexate disodium

Cat.No: T8003

Target: Apoptosis, Dehydrogenase, DNA/RNA Synthesis, Antifolate, ADC Cytotoxin

Cat.No: T14864

Synonym: NSC-253272,卡醋胺

Target: Others, DNA/RNA Synthesis, Antibacterial

Cat.No: T6994

Synonym: SR-12813,SR 12813,GW 485801

Target: HMG-CoA Reductase, Autophagy

Cat.No: T35317

Synonym: CP 73850,CP73850,CP-73850,唑泊司他,Zopolrestatum

Target: Reductase

Cat.No: T3693

Synonym: 7-bromoquinazoline-2,4-diamine,7-溴-2,4-二氨基喹唑啉

Target: Others, DHFR

Cat.No: T3157

Synonym: RNR Inhibitor COH29

Target: DNA/RNA Synthesis

Cat.No: T12092

Synonym: Antibiotic MB 530A,Lovastatin diol lactone,辛伐他汀内酯二醇

Target: HMG-CoA Reductase, Autophagy

Cat.No: T15568

Synonym: Alcon 1576,AL 1576,咪瑞司他,HOE 843

Target: Reductase

Cat.No: T6120

Synonym: Folotyn,10-炔丙基-10-去氮杂氨基蝶呤,10-Propargyl-10-deazaaminopterin,普拉曲沙

Target: Apoptosis, DHFR, Antifolate, TAM Receptor

Atorvastatin hemicalcium salt

Cat.No: T3116

Synonym: Lipitor,Atorvastatin hemicalcium,Atorvastatin Calcium,CI-981,阿托伐他汀钙,Sortis

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Cat.No: T1676

Synonym: 罗伐他汀,ZD 4522,瑞舒伐他汀

Target: Potassium Channel, HMG-CoA Reductase, Autophagy

Pitavastatin calcium

Cat.No: T2534

Synonym: P-872441,nisvastatin,itavastatin,Pitavastatin hemicalcium,匹伐他汀钙,NK-104

Target: Apoptosis, Mitophagy, Endogenous Metabolite, HMG-CoA Reductase, Autophagy

Rosuvastatin calcium

Cat.No: T1510

Synonym: ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium,瑞舒伐他汀钙

Target: Potassium Channel, HMG-CoA Reductase, Autophagy

Cat.No: T1485

Synonym: NCI-C04671,WR19039,Amethopterin,甲氨蝶呤,CL14377

Target: Apoptosis, Dehydrogenase, DNA/RNA Synthesis, Antifolate, ADC Cytotoxin

Cat.No: T20765

Synonym: 阿托伐他汀,阿伐他汀

Target: HMG-CoA Reductase, Autophagy

Cat. No.	Product Name	Target	Signaling Pathways
TN2601	12-O-Methylcarnosic acid	Reductase	Endocrinology/Hormones; Metabolism
	12-O-Methylcarnosic acid 是分离自小叶丹参的丙酮提取物的一种二萜肉桂酸，可抑制 5α-还原酶 (5α-reductase) 活性，IC50为 61.7 μM。它抑制 LNCaP 细胞的增殖。它具有抗微生物活性、抗氧化和抗癌活性。
T6S2384	Poliumoside	Reductase	Endocrinology/Hormones; Metabolism
	Poliumoside 是从 Brandisia hancei 的茎和叶中分离出来的咖啡酰化的苯丙烷糖苷。Poliumoside 能够抑制晚期糖基化终产物的形成和大鼠晶状体醛糖还原酶，IC50分别为 19.69 和 8.47 μM。Poliumoside 具有抗炎和抗氧化特性。
T8115	Menthofuran	Others	Others
	Menthofuran 是一种天然产品。
T3378	Alpha-Estradiol α-雌二醇,Alfatradiol,雌二醇,17α-Estradiol,Epiestrol,Epiestradiol	Estrogen/progestogen Receptor; Reductase; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Alpha-Estradiol (Epiestradiol) 是一种雌性激素，可抑制5α-reductase，在雄原性脱发的研究中有潜力。
TN1733	Hesperetin 7-O-glucoside	Anti-infection; Antibacterial; HMG-CoA Reductase	Metabolism; Microbiology/Virology
	Hesperetin 7-O-glucoside 是通过 Hesperidin 的酶促转化产生的一种人 HMG-CoA 还原酶抑制剂，具有降压作用，可抑制幽门螺杆菌的生长。
TN6715	7-Ketocholesterol	Others	Others
	7-Ketocholesterol 是胆固醇的代谢物。
T5S1131	Ganoderic acid C6 灵芝酸C6	Others	Others
	Ganoderic acid C6 是醛糖还原酶活性的抑制剂。
T1207	Lovastatin MK-803,洛伐他汀,Mevinolin	Ferroptosis; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Lovastatin (MK-803) 是一种 HMG-CoA 还原酶抑制剂，用于降低胆固醇。
T0683	Mevastatin Compactin,ML236B,美伐他汀	Apoptosis; Antibacterial; Antibiotic; HMG-CoA Reductase; Autophagy; Lipid	Apoptosis; Autophagy; Metabolism; Microbiology/Virology
	Mevastatin (ML236B) 是他汀类 HMG-CoA 还原酶抑制剂。它是一种降脂药，可诱导细胞凋亡，将癌细胞阻滞在 G0/G1期。它还可增加内皮型一氧化氮合酶的 mRNA 和蛋白质水平。它有抗肿瘤活性，用于心血管疾病的研究。
T0725	Isoliquiritigenin 异甘草素,ISL,Isoliquiritigen,GU17	Apoptosis; Influenza Virus; Reductase; Autophagy	Apoptosis; Autophagy; Endocrinology/Hormones; Metabolism; Microbiology/Virology
	Isoliquiritigenin (ISL) 是从光果甘草根中分离得到的一种黄酮类天然产物，具有抗肿瘤的活性。它抑制流感病毒复制，EC50为 24.7 μM，还能抑制 aldose reductase 的活性，IC50值为 320 nM。
T1664	Meglutol Dicrotalic acid,3-Hydroxy-3-methylglutaric acid,美格鲁托	Endogenous Metabolite; HMG-CoA Reductase; Autophagy	Autophagy; Metabolism
	Meglutol (3-Hydroxy-3-methylglutaric acid) 是一种抗血脂剂，可降低胆固醇、甘油三酯、血清 β-脂蛋白和磷脂。它抑制胆固醇生物合成中的限速酶羟甲基戊二酰辅酶 A 还原酶的活性。
TN1438	beta-Amyrin acetate beta-香树脂醇乙酸酯	Antioxidant; HMG-CoA Reductase; Epoxide Hydrolase; Antifungal	Metabolism; Microbiology/Virology; oxidation-reduction
	beta-Amyrin acetate 抑制 HMG-CoA 还原酶 (HMGCR) 和 sEH 活性，IC50 为 3.4 μM。 beta-Amyrin acetate 具有抗炎、抗真菌、抗氧化和抗高血脂活性。
T0687	Simvastatin 辛伐他汀,MK-0733,MK 733	Apoptosis; Mitophagy; Ferroptosis; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Simvastatin (MK 733) 是一种 HMG-CoA 还原酶抑制剂 (Ki=0.2 nM)，具有口服活性。Simvastatin 具有降血脂活性，可以抑制肝脏产生胆固醇，还可以用于预防心血管疾病。
T0672	Pravastatin sodium CS-514 Sodium,普伐他汀钠,CS-514 (sodium)	Ferroptosis; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Pravastatin sodium (CS-514 (sodium)) 是一种 HMG-CoA 还原酶抑制剂，抑制甾醇合成，IC50 为 5.6 μM。
T1153	Trimethoprim NIH 204,BW 56-72,甲氧苄啶,NSC-106568	DHFR; DNA/RNA Synthesis; Antifolate; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Trimethoprim (NSC-106568) 是抑菌抗生素，也是具有口服活性的二氢叶酸还原酶抑制剂。它对多种革兰氏阳性和革兰氏阴性需氧细菌具有活性，可用于尿路感染，肺孢子菌肺炎和志贺氏菌病的研究。
T3801	(Rac)-Byakangelicin 白当归素,Bjacangelicin,Bjakangelicin,Biacangelicin,7H-Furo[3,2-g][1]benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-,Byakangelicin	Others	Others
	(Rac)-Byakangelicin (7H-Furo[3,2-g][1]benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-) 是一种 Byakangelicin 的外消旋体，主要分离自 Angelica 属中。其中 Byakangelicin 是醛糖还原酶抑制剂(IC50:6.2 μM)，可用作抗肿瘤剂。
TN1661	Ganoderic acid C2 灵芝酸 C2	Reductase; Histamine Receptor; Immunology/Inflammation related	Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
	Ganoderic acid C2 是分离自灵芝的一种三萜化合物，具有潜在的抗肿瘤生物活性，以及抗组胺、抗衰老和细胞毒性作用。它对rat lens aldose reductase 具有很高的抑制活性，IC50为 3.8 µM。
TN1016	Kukoamine A	NF-κB; Lipoxygenase; DNA/RNA Synthesis; Parasite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; NF-κB
	Kukoamine A 是一种天然的精胺衍生物，具有抗癌、抗高血压、细胞保护、抗氧化和抗炎活性。它是锥虫硫磷还原酶抑制剂，Ki 值为 1.8 μM。
T5372	L-SelenoMethionine L-(+)-Selenomethionine,L-硒代蛋氨酸	Apoptosis; Amino Acids and Derivatives; Endogenous Metabolite	Apoptosis; Metabolism
	L-SelenoMethionine (L-(+)-Selenomethionine) 是 Selenomethionine 的 L-异构体，是硒的主要天然食物形式。它是一种癌症化学预防剂，可以增加谷胱甘肽过氧化物酶的表达，还可以通过饮食补充降低癌症的发生率并诱导癌细胞凋亡。
T3329	4',7-Dimethoxyisoflavone 4',7-二甲氧基异黄酮,Dimethoxydaidzein,Daidzein dimethyl ether	Endogenous Metabolite; Antifungal	Metabolism; Microbiology/Virology
	4',7-Dimethoxyisoflavone (Daidzein dimethyl ether) 是从阔荚合欢中分离的黄酮类化合物，有抗真菌作用，可抑制大鼠前列腺睾酮5α-还原酶。
TN1975	Neosmitilbin Neoastilbin,新落新妇苷	Others	Others
	Neosmitilbin (Neoastilbin) 分离于 Garcinia mangostana。它能够有效抑制晶状体醛糖还原酶的活性，可能具有抗氧化和抗炎作用。
T5S0543	Isocurcumenol	Apoptosis; Estrogen Receptor/ERR; Reductase	Apoptosis; Endocrinology/Hormones; Metabolism
	Isocurcumenol 是从莪术中分离得到的一种天然产物，是一种ERα抑制剂，对 DLA 和 KB 癌细胞的IC50分别为 99.1 µg/mL 和 178.2 µg/mL，具有抗肿瘤活性。
T10183	6-Methoxytricin	Reductase	Endocrinology/Hormones; Metabolism
	6-Methoxytricin 是从积雪草中分离的黄酮类化合物，是醛糖还原酶 (AR) 和晚期糖基化终产物 (AGE) 的抑制剂，抑制生物细胞中的T细胞增殖和活化。
TN1656	Ganoderenic acid A 灵芝烯酸A,灵芝烯酸 A	Others	Others
	Ganoderenic acid A 是三萜类化合物。它对 CCl4 诱导的肝损伤具有保护作用。它是β-葡萄糖醛酸酶抑制剂。
T3S0507	Homovanillic acid Homovaniuic acid,Vanilacetic acid,高香草酸,Vanillacetic acid	Others; Endogenous Metabolite	Metabolism; Others
	Homovanillic acid (Vanillacetic acid) 是一种多巴胺代谢物，它与乳糜泻、生长激素缺乏、芳香族氨基酸脱羧酶缺乏症以及脂联素还原酶缺乏症相关。
T7730	Aminopterin APGA,氨基蝶呤,4-Aminofolic acid	Antifolate	Cell Cycle/Checkpoint
	Aminopterin (4-Aminofolic acid) 是叶酸的 4-氨基衍生物，是叶酸拮抗剂，具有抗癌和免疫抑制活性，用于研究儿童白血病。它催化叶酸还原为四氢叶酸，竞争性抑制二氢叶酸还原酶，Ki 值为 3.7 pM。
TN5845	Neochlorogenic acid methyl ester 5-O-Caffeoylquinic acid methyl ester,Methyl 3-caffeoylquinate,GIP (1-39) acetate(725474-97-5 Free base),Methyl neochlorogenate,新绿原酸甲酯	Antioxidant; HBV	Microbiology/Virology; oxidation-reduction
	Neochlorogenic acid methyl ester (5-O-Caffeoylquinic acid methyl ester) 来源于毛蒿和黑色苦莓(Aronia melanocarpa)果实。Neochlorogenic acid methyl ester 显示出抗 HBV 活性、抗氧化活性和醌还原酶活性，CD 为 6.7 μM。
T6S0840	Engeletin Dihydrokaempferol 3-rhamnoside,黄杞苷	NF-κB; Reductase	Endocrinology/Hormones; Metabolism; NF-κB
	Engeletin (Dihydrokaempferol 3-rhamnoside) 是一种黄酮苷类物质，从hymenaea martiana 中获得，抑制NF-κB 信号通路的激活，具有抗炎、缓解疼痛、消肿、利尿、抗菌等作用。
T8072	S-Methyl-L-cysteine S-甲基-L-半胱氨酸,S-Methylcysteine	Antioxidant; Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
	S-Methyl-L-cysteine (S-Methylcysteine) 是一种催化抗氧化系统中甲硫氨酸硫氧化物还原酶 A 的作用底物，是一种天然产物，具有抗氧化、神经保护及减肥的功效。
T5S1026	Apigenin-7-glucuronide Apigenin 7-O-glucuronide,芹菜素-7-葡萄糖醛酸	MMP	Proteases/Proteasome
	Apigenin-7-glucuronide (Apigenin 7-O-glucuronide) 能够抑制基质金属蛋白酶的活性，其对 MMP-3 (IC50:12.87 μM)，MMP-8 (IC50:22.39 μM)，MMP-9 (IC50:17.52 μM)，MMP-13 (IC50:0.27 μM)。
TN2030	P-Hydroxyphenethyl trans-ferulate 反式-阿魏酸对羟基苯乙酯	5-HT Receptor	GPCR/G Protein; Neuroscience
	p-Hydroxyphenethyl trans-ferulate 具有抗高血糖（酵母α-葡萄糖苷酶，IC5019.24 ± 1.73 µmol L-1），抗氧化，抗炎活性，也具有抗癌特性和血清素能特性。
T14128	Adenosylcobalamin Cobamamide,Coenzyme B12,腺苷钴胺,AdoCbl	Endogenous Metabolite	Metabolism
	Adenosylcobalamin (AdoCbl) 是一种 Vitamin B12的特性形式，其中 Vitamin B12 是是甲基丙二酰 CoA 突变酶的辅助因子。
TN2122	Quercetin 3-gentiobioside Quercetin-3-gentiobioside	Reductase	Endocrinology/Hormones; Metabolism
	Quercetin 3-gentiobioside (Quercetin-3-gentiobioside) 是一种AR 和 AGE 形成的抑制剂，可从 A. iwayomogi 中提取。Quercetin 3-gentiobioside 对醛糖还原酶 (AR) 的生物活性和晚期糖基化终产物 (AGEs) 的形成具有抑制作用。
T3665	Tectoridin 射干苷,Shekanin	Estrogen Receptor/ERR; Reductase	Endocrinology/Hormones; Metabolism
	Tectoridin (Shekanin) 是分离自 Maackia amurensis 中的异黄酮，是一种植物雌激素，能够激活雌激素和甲状腺激素受体。它通过 ER 依赖性基因组途径和 GPR30 依赖性非基因组途径发挥雌激素作用。
T4717	25-Hydroxycholesterol 25-羟基胆固醇,25-羟基胆甾醇	Others; Endogenous Metabolite; HMG-CoA Reductase	Metabolism; Others
	25-Hydroxycholesterol 是胆固醇的代谢产物，由巨噬细胞响应 Toll 样受体激活而分泌。它有效抑制 B 细胞产生 IgA，EC50约为 65 nM。
TN2111	Prunin Naringenin 7-0-glucoside,柚皮素-7-O-葡萄糖苷	Phosphatase; Anti-infection; Virus Protease	Metabolism; Microbiology/Virology
	Prunin (Naringenin 7-0-glucoside) 是一种人肠道病毒 A71 抑制剂。它抑制蛋白酪氨酸磷酸酶 1B，IC50值为 5.5 μM。
TN2272	Tigloylgomisin H	Nrf2	Immunology/Inflammation
	Tigloylgomisin H 是分离自S. chinensis 果实中的木酚素。Tigloylgomisin H 能诱导小鼠肝癌细胞 Hepa1c1c7 中醌还原酶活性。Tigloylgomisin H 是单功能诱导剂，通过 Nrf2-ARE 途径特异性上调 II 期解毒酶 NQO1。Tigloylgomisin H 是潜在的肝癌预防剂。
T5S1988	Isorhamnetin-3-O-glucoside Isorhamnetin-3-O-beta-D-Glucoside,异鼠李素-3-O-葡萄糖苷	Others	Others
	Isorhamnetin-3-O-glucoside (Isorhamnetin-3-O-beta-D-Glucoside) 是一种天然化合物，广泛存在于蔬菜和水稻中，经消化后可在肠道菌群中代谢。
T5813	BYAKANGELICIN	Reductase	Endocrinology/Hormones; Metabolism
	Byakangelicin 是发现于当归根中的一种活性化合物，可作为调节剂，改善各种活性化合物 (Umb，Cur 和 Dox) 的脑积累，增强研究效果。它提高所有PXR 靶基因 (如MDR1) 的表达，并广泛的诱导药物-药物相互作用。它可抑制性激素的作用，可能会增加内源激素的分解代谢。
TN1037	Groenlandicine	Topoisomerase	DNA Damage/DNA Repair
	Groenlandicine 是来自黄连的一种原小檗碱生物碱，能诱导拓扑异构酶 I 介导的 DNA 裂解。它对人类重组醛糖还原酶(HRAR)具有中度的抑制作用，IC50值为 154.2 μM。
T6102	2'-acetylacteoside	Antioxidant; Reductase	Endocrinology/Hormones; Metabolism; oxidation-reduction
	2'-Acetylacteoside 是一种苯乙醇苷类化合物，分离自来江藤中，可抑制自由基诱导的红细胞溶血，具有清除自由基的作用。
T2S1635	3-Isomangostin	MTH1	DNA Damage/DNA Repair
	3-Isomangostin 可从莽吉柿壳中提取的一种天然产物，是一种乙酰胆碱酯酶选择性抑制剂，也是一种有效的人醛糖还原酶抑制剂，IC50 为 3.48 uM。它抑制 MutT 同源物 1 (MTH1)，IC50 为 52 nM。它具有清除自由基、抗疟原虫和抗癌的活性。
TL0008	Gigantol	Wnt/beta-catenin; Glucosidase	Cytoskeletal Signaling; Metabolism; Stem Cells
	Gigantol 是一种联苄基化合物，从几种药用兰花中获得，是一种Wnt/β-catenin 通路抑制剂，具有抗肿瘤活性。
T4918	DL-Glyceraldehyde Glyceric aldehyde,DL-甘油醛晶体	Reductase	Endocrinology/Hormones; Metabolism
	DL-Glyceraldehyde (Glyceric aldehyde) 是由酶甘油醛脱氢酶的作用产生的，该酶使用 NADP 作为辅因子将甘油转化为甘油醛。它是一种高活性化合物，可以修饰和交联蛋白质。
T19365	Hydroxypyruvic acid 3-Hydroxypyruvic acid,β-Hydroxypyruvic acid	Others	Others
	Hydroxypyruvic acid is an intermediate in the metabolism of glycine, serine, and threonine. It is a substrate for serine-pyruvate aminotransferase and glyoxylate reductase/hydroxypyruvate reductase.
TN6514	2-Carboxybenzaldehyde
	The major peak of 2-Carboxybenzaldehyde reductase activity in human liver co-purifies with hAFAR protein. Sulphydryl substances and some proteins play important roles in preserving the molecular and catalytic properties of 2-Carboxybenzaldehyde reductase.
TN5183	Triptocalline A	Others	Others
	Triptocalline A shows an inhibitory effect on rat lens aldose reductase.
T81570	Paecilaminol FKI-0550
	Paecilaminol (FKI-0550) 为一种高效的 NADH 富马酸还原酶 (NADH-fumarate reductase) 抑制剂，其对蛔虫 (Ascaris suum) NADH 富马酸还原酶展现了 5.1 μM 的 IC50 值。
T19576	Tetrahydrocortisone	Others	Others
	Tetrahydrocortisone, a stress-induced hormone and a urinary metabolite of Cortisone, originates from the reduction of Cortisone facilitated by 5-reductase.
T39435	Myrciacetin	Others	Others
	Myrciacetin, a flavonoid derived from Rhododendron dauricum, exhibits inhibitory activity against rat lens aldose reductase, as demonstrated by an IC50 value of 13 μM.
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天然产物

12-O-Methylcarnosic acid

Cat.No: TN2601

Target: Reductase

Cat.No: T6S2384

Target: Reductase

Cat.No: T8115

Target: Others

Alpha-Estradiol

Cat.No: T3378

Synonym: α-雌二醇,Alfatradiol,雌二醇,17α-Estradiol,Epiestrol,Epiestradiol

Target: Estrogen/progestogen Receptor, Reductase, Endogenous Metabolite

Hesperetin 7-O-glucoside

Cat.No: TN1733

Target: Anti-infection, Antibacterial, HMG-CoA Reductase

7-Ketocholesterol

Cat.No: TN6715

Target: Others

Ganoderic acid C6

Cat.No: T5S1131

Synonym: 灵芝酸C6

Target: Others

Cat.No: T1207

Synonym: MK-803,洛伐他汀,Mevinolin

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Cat.No: T0683

Synonym: Compactin,ML236B,美伐他汀

Target: Apoptosis, Antibacterial, Antibiotic, HMG-CoA Reductase, Autophagy, Lipid

Isoliquiritigenin

Cat.No: T0725

Synonym: 异甘草素,ISL,Isoliquiritigen,GU17

Target: Apoptosis, Influenza Virus, Reductase, Autophagy

Cat.No: T1664

Synonym: Dicrotalic acid,3-Hydroxy-3-methylglutaric acid,美格鲁托

Target: Endogenous Metabolite, HMG-CoA Reductase, Autophagy

beta-Amyrin acetate

Cat.No: TN1438

Synonym: beta-香树脂醇乙酸酯

Target: Antioxidant, HMG-CoA Reductase, Epoxide Hydrolase, Antifungal

Cat.No: T0687

Synonym: 辛伐他汀,MK-0733,MK 733

Target: Apoptosis, Mitophagy, Ferroptosis, HMG-CoA Reductase, Autophagy

Pravastatin sodium

Cat.No: T0672

Synonym: CS-514 Sodium,普伐他汀钠,CS-514 (sodium)

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Cat.No: T1153

Synonym: NIH 204,BW 56-72,甲氧苄啶,NSC-106568

Target: DHFR, DNA/RNA Synthesis, Antifolate, Antibacterial, Antibiotic

(Rac)-Byakangelicin

Cat.No: T3801

Synonym: 白当归素,Bjacangelicin,Bjakangelicin,Biacangelicin,7H-Furo[3,2-g][1]benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-,Byakangelicin

Target: Others

Ganoderic acid C2

Cat.No: TN1661

Synonym: 灵芝酸 C2

Target: Reductase, Histamine Receptor, Immunology/Inflammation related

Cat.No: TN1016

Target: NF-κB, Lipoxygenase, DNA/RNA Synthesis, Parasite

L-SelenoMethionine

Cat.No: T5372

Synonym: L-(+)-Selenomethionine,L-硒代蛋氨酸

Target: Apoptosis, Amino Acids and Derivatives, Endogenous Metabolite

4',7-Dimethoxyisoflavone

Cat.No: T3329

Synonym: 4',7-二甲氧基异黄酮,Dimethoxydaidzein,Daidzein dimethyl ether

Target: Endogenous Metabolite, Antifungal

Cat.No: TN1975

Synonym: Neoastilbin,新落新妇苷

Target: Others

Cat.No: T5S0543

Target: Apoptosis, Estrogen Receptor/ERR, Reductase

6-Methoxytricin

Cat.No: T10183

Target: Reductase

Ganoderenic acid A

Cat.No: TN1656

Synonym: 灵芝烯酸A,灵芝烯酸 A

Target: Others

Homovanillic acid

Cat.No: T3S0507

Synonym: Homovaniuic acid,Vanilacetic acid,高香草酸,Vanillacetic acid

Target: Others, Endogenous Metabolite

Cat.No: T7730

Synonym: APGA,氨基蝶呤,4-Aminofolic acid

Target: Antifolate

Neochlorogenic acid methyl ester

Cat.No: TN5845

Synonym: 5-O-Caffeoylquinic acid methyl ester,Methyl 3-caffeoylquinate,GIP (1-39) acetate(725474-97-5 Free base),Methyl neochlorogenate,新绿原酸甲酯

Target: Antioxidant, HBV

Cat.No: T6S0840

Synonym: Dihydrokaempferol 3-rhamnoside,黄杞苷

Target: NF-κB, Reductase

S-Methyl-L-cysteine

Cat.No: T8072

Synonym: S-甲基-L-半胱氨酸,S-Methylcysteine

Target: Antioxidant, Reactive Oxygen Species

Apigenin-7-glucuronide

Cat.No: T5S1026

Synonym: Apigenin 7-O-glucuronide,芹菜素-7-葡萄糖醛酸

Target: MMP

P-Hydroxyphenethyl trans-ferulate

Cat.No: TN2030

Synonym: 反式-阿魏酸对羟基苯乙酯

Target: 5-HT Receptor

Adenosylcobalamin

Cat.No: T14128

Synonym: Cobamamide,Coenzyme B12,腺苷钴胺,AdoCbl

Target: Endogenous Metabolite

Quercetin 3-gentiobioside

Cat.No: TN2122

Synonym: Quercetin-3-gentiobioside

Target: Reductase

Cat.No: T3665

Synonym: 射干苷,Shekanin

Target: Estrogen Receptor/ERR, Reductase

25-Hydroxycholesterol

Cat.No: T4717

Synonym: 25-羟基胆固醇,25-羟基胆甾醇

Target: Others, Endogenous Metabolite, HMG-CoA Reductase

Cat.No: TN2111

Synonym: Naringenin 7-0-glucoside,柚皮素-7-O-葡萄糖苷

Target: Phosphatase, Anti-infection, Virus Protease

Tigloylgomisin H

Cat.No: TN2272

Target: Nrf2

Isorhamnetin-3-O-glucoside

Cat.No: T5S1988

Synonym: Isorhamnetin-3-O-beta-D-Glucoside,异鼠李素-3-O-葡萄糖苷

Target: Others

Cat.No: T5813

Target: Reductase

Cat.No: TN1037

Target: Topoisomerase

2'-acetylacteoside

Cat.No: T6102

Target: Antioxidant, Reductase

Cat.No: T2S1635

Target: MTH1

Cat.No: TL0008

Target: Wnt/beta-catenin, Glucosidase

DL-Glyceraldehyde

Cat.No: T4918

Synonym: Glyceric aldehyde,DL-甘油醛晶体

Target: Reductase

Hydroxypyruvic acid

Cat.No: T19365

Synonym: 3-Hydroxypyruvic acid,β-Hydroxypyruvic acid

Target: Others

2-Carboxybenzaldehyde

Cat.No: TN6514

Triptocalline A

Cat.No: TN5183

Target: Others

Cat.No: T81570

Synonym: FKI-0550

Tetrahydrocortisone

Cat.No: T19576

Target: Others

Cat.No: T39435

Target: Others

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00288	Adrenodoxin reductase Protein, Bovine, Recombinant (His) Ferredoxin reductase,Adrenodoxin reductase...	Bovine	P. pastoris (Yeast)
	Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. Adrenodoxin reductase Protein, Bovine, Recombinant (His) is expressed in yeast with N-10xHis tag. The predicted molecular weight is 52.8 kDa and the accession number is P08165.
TMPH-01224	Dihydrofolate reductase Protein, Human, Recombinant (His) DHFR,Dihydrofolate reductase	Human	E. coli
	Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFR2.
TMPH-00658	NAD(P)H-flavin reductase Protein, E. coli, Recombinant (His) Riboflavin reductase [NAD(P)H],Ferrisiderophore	E. coli	E. coli
	Catalyzes the reduction of soluble flavins by reduced pyridine nucleotides.
TMPH-00287	Adrenodoxin reductase Protein, Bovine, Recombinant (E. coli, His) Ferredoxin--NADP(+) reductase,ADXR,NADPH:adrenodoxi...	Bovine	E. coli
	Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. Adrenodoxin reductase Protein, Bovine, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 55.8 kDa and the accession number is ...
TMPH-00625	FMN reductase Protein, E. coli, Recombinant (His) FMN reductase,ssuE,FMN reductase (NADPH),S...	E. coli	Baculovirus Insect Cells
	Catalyzes an NADPH-dependent reduction of FMN, but is also able to reduce FAD or riboflavin.
TMPH-00608	Dihydrofolate reductase Protein, E. coli, Recombinant (His) Dihydrofolate reductase,folA,tmrA	E. coli	E. coli
	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
TMPH-03535	Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc) DHFR,Dihydrofolate reductase,folA	Staphylococcus aureus	E. coli
	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 25.6 kDa and the accession number is P99079.
TMPH-03581	Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His) dfrC,folA1,Dihydrofolate reductase,folA,DHFR	Staphylococcus epidermidis	E. coli
	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 22.0 kDa and the accession number is P0C0P1.
TMPH-00683	TMAO reductase 1 Protein, E. coli O157:H7, Recombinant (His & Myc) Trimethylamine-N-oxide reductase 1,torA	E. coli	E. coli
	Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.
TMPH-00007	HMGCR Protein, Human, Recombinant (His) HMGCR,3-hydroxy-3-methylglutaryl-coenzyme A reductase	Human	E. coli
	Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR is the main target of statins, a class of cholesterol-lowering drugs.
TMPJ-00937	RRM2 Protein, Human, Recombinant (His) RRM2,RR2,Ribonucleotide Reductase Small Subunit,Rib...	Human	HEK293 Cells
	Ribonucleoside-Diphosphate Reductase Subunit M2 (RRM2) belongs to the ribonucleoside diphosphate reductase small chain family. The reductase of RRM2 catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. RRM2 supplies the precursors essential for DNA synthesis. RRM2 catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Phosphorylation on Ser-20 relieves the in...
TMPH-02686	GLXR Protein, Mouse, Recombinant (His & SUMO) Grhpr,Glyoxylate reductase/hydroxypyruvate redu...	Mouse	E. coli
	Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate oxidizes D-glycerate to hydroxypyruvate.
TMPH-00218	DHCR7 Protein, Bovine, Recombinant (His) DHCR7,7-dehydrocholesterol reductase,Sterol Delta(7...	Bovine	E. coli
	7-dehydrocholesterol reductase of the cholesterol biosynthetic pathway reducing the C7-C8 double bond of cholesta-5,7-dien-3beta-ol (7-dehydrocholesterol/7-DHC) and cholesta-5,7,24-trien-3beta-ol, two intermediates in that pathway. DHCR7 Protein, Bovine, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 55.8 kDa and the accession number is Q5E9J5.
TMPH-03020	MTR Protein, Mycobacterium tuberculosis, Recombinant (His & Myc & SUMO) mtr,Mycothione reductase,Mycothiol-disulfide re...	Mycobacterium tuberculosis	E. coli
	Catalyzes the NAD(P)H-dependent reduction of mycothione (the oxidized disulfide form of mycothiol) to mycothiol.
TMPH-00578	NrdD Protein, E. coli, Recombinant (His) nrdD,Class III ribonucleoside-triphosphate reductase	E. coli	E. coli
	Catalyzes the conversion of ribonucleotides into deoxyribonucleotides, which are required for DNA synthesis and repair. NrdD Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 84.0 kDa and the accession number is P28903.
TMPJ-00813	QDPR Protein, Human, Recombinant (His) Dihydropteridine Reductase,QDPR,DHPR,HDHPR,Quinoid ...	Human	HEK293 Cells
	Dihydropteridine reductase, also known as HDHPR and Quinoid dihydropteridine reductase, QDPR and DHPR, belongs to the short-chain dehydrogenases/reductases (SDR) family. QDPR exists as a homodimer. QDPR is part of the pathway that recycles a substance called tetrahydrobiopterin, also known as BH4 and tryptophan hydroxylases. The regeneration of this substance is critical for the proper processing of several other amino acids in the body. Tetrahydrobiopterin also helps produce certain chemicals i...
TMPH-03196	PYCR Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) PCA reductase,Pyrroline-5-carboxylate reductase...	Mycobacterium tuberculosis	E. coli
	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. PYCR Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 37.6 kDa and the accession number is P9WHU7.
TMPJ-01009	BLVRA Protein, Human, Recombinant (His) Biliverdin reductase A,BVR,BVR A,BLVR,BLVRA,Biliver...	Human	E. coli
	Human Biliverdin reductase A (BLVRA) is belonged to the Gfo/Idh/MocA family and Biliverdin reductase subfamily. BLVRA is an enzyme that in humans is encoded by the BLVRA gene. BLVRA plays an important role in reducing the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor. BLVRA acts on biliverdin by reducing its double-bond between the pyrrole rings into a single-bond. It accomplishes this using NADPH + H+ ...
TMPH-01761	Neuroglobin Protein, Human, Recombinant (His & SUMO) Nitrite reductase,Neuroglobin,NGB	Human	E. coli
	Neuroglobin Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 32.9 kDa and the accession number is Q9NPG2.
TMPH-03191	NirS Protein, Pseudomonas stutzeri, Recombinant (His & Myc) Nitrite reductase,Cytochrome oxidase,Hydroxylamine ...	Pseudomonas stutzeri	E. coli
	N/A. NirS Protein, Pseudomonas stutzeri, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 56.0 kDa and the accession number is P24040.
TMPH-03008	ENR Protein, Mycobacterium tuberculosis, Recombinant (His) FAS-II enoyl-ACP reductase,Enoyl-ACP reductase<...	Mycobacterium tuberculosis	E. coli
	ENR Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 32.6 kDa and the accession number is P9WGR0.
TMPY-03617	GMPR Protein, Human, Recombinant (His) GMPR1,guanosine monophosphate reductase	Human	E. coli
	GMPR, also known as GMPR1, belongs to the IMPDH/GMPR family.This familyofenzymesincludesIMP dehydrogenaseandGMP reductase. These enzymes are involved inpurine metabolism and adopt aTIM barrelstructure. GMPR is an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. GMPR functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
TMPH-00564	FabG Protein, E. coli, Recombinant (His & Myc) Beta-Ketoacyl-acyl carrier protein reductase,fabG,B...	E. coli	E. coli
	Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
TMPY-00354	MSRB3 Protein, Human, Recombinant (hFc) methionine sulfoxide reductase B3,DFNB74	Human	HEK293 Cells
	MSRB3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.7 kDa and the accession number is Q8IXL7-1.
TMPY-00538	MSRB3 Protein, Human, Recombinant (His) methionine sulfoxide reductase B3,DFNB74	Human	HEK293 Cells
	MSRB3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.4 kDa and the accession number is Q8IXL7-2.
TMPH-02174	PYCR1 Protein, Human, Recombinant (His & SUMO) pyrroline-5-carboxylate reductase	Human	E. coli
	PYCR1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli with N-terminal 6xHis-SUMO tag. The predicted molecular weight is 33.7 kDa. Accession number: Q8TBX0
TMPY-03867	CBR3 Protein, Human, Recombinant (His) SDR21C2,carbonyl reductase 3,hCBR3,HEL-S-25	Human	E. coli
	CBR3, also known as hCBR3, belongs to the short-chain dehydrogenases/reductases (SDR) family. CBR3 is expressed in ovary, pancreas, intestine, colon, kidney, brain, thymus, lung, heart, liver, spleen, leukocyte, prostate and testis. It is a monomeric NADPH-dependent oxidoreductase and is closely linked to another carbonyl reductase gene – CBR1. CBR3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. It has lo...
TMPH-02198	TXNRD2 Protein, Human, Recombinant (His & SUMO) TR-beta,Thioredoxin reductase 2, mitochondrial,Thio...	Human	E. coli
	Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis. Maintains thioredoxin in a reduced state. May play a role in redox-regulated cell signaling.
TMPH-02797	NQO1 Protein, Mouse, Recombinant (His) Quinone reductase 1,NAD(P)H dehydrogenase [quinone]...	Mouse	P. pastoris (Yeast)
	The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. NQO1 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 32.8 kDa and the accession number is Q64669.
TMPH-03536	FabI Protein, S. aureus, Recombinant (His & SUMO) Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI...	Staphylococcus aureus	E. coli
	Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism. FabI Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.0 kDa and the accession number is Q6GI75.
TMPH-02794	Myoglobin Protein, Mouse, Recombinant (E. coli, His & Myc) Nitrite reductase MB,Mb,Pseudoperoxidase MB,Myoglob...	Mouse	E. coli
	Myoglobin Protein, Mouse, Recombinant (E. coli, His & Myc) is expressed in E. coli.
TMPY-02438	AKR1B1 Protein, Human, Recombinant (His) ALDR1,AR,ADR,aldo-keto reductase family 1, member B...	Human	E. coli
	Aldose reductase (AKR1B1) belongs to the aldo/keto reductase superfamily. AKR1B1 is a NADPH-dependent aldo-keto reductase best known as the rate-limiting enzyme of the polyol pathway. Expression of AKR1B1 was the highest in lens and retina. It is the first enzyme in the polyol pathway through which glucose is converted to sorbitol which is important for the function of various organs in the body, and has been implicated in the etiology of diabetic complications. AKR1B1 is quite abundant in the c...
TMPY-02461	AKR1A1 Protein, Human, Recombinant (His) DD3,ALDR1,HEL-S-6,aldo-keto reductase family 1, mem...	Human	E. coli
	Aldehyde reductase (AKR1A1) is a member of the aldo-keto reductase superfamily, which consists of more than 40 known enzymes and proteins that includes variety of monomeric NADPH-dependent oxidoreductases, such as aldehyde reductase. Aldehyde reductase has wide substrate specificities for carbonyl compounds. These enzymes are implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Aldehyde reductase possess a structure with a beta-alpha-beta fo...
TMPY-03287	RRM1 Protein, Human, Recombinant (His & GST) ribonucleotide reductase M1,R1,RR1,RIR1	Human	Baculovirus Insect Cells
	RRM1 is a subunit of ribonucleoside-diphosphate reductase which is constituted by two subunits. Ribonucleoside-diphosphate reductase is an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. RRM1 is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocort...
TMPH-00725	NarG Protein, E. coli, Recombinant (His & Myc) narG,Quinol-nitrate oxidoreductase subunit alpha,Re...	E. coli	E. coli
	The nitrate reductase enzyme complex allows E.coli to use nitrate as an electron acceptor during anaerobic growth. The alpha chain is the actual site of nitrate reduction.
TMPH-02795	Myoglobin Protein, Mouse, Recombinant (His & Myc) Mb,Nitrite reductase MB,Myoglobin,Pseudoperoxidase ...	Mouse	HEK293 Cells
	Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. Myoglobin Protein, Mouse, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 21.9 kDa and the accession number is P04247.
TMPY-01812	Enoyl-ACP Reductase Protein, E. coli, Recombinant (His) b1288,JW1281,gts,ECK1283,qmeA,envM	E. coli	E. coli
	Enoyl-ACP reductase, also known as NADH-dependent enoyl-ACP reductase and FABI, is a cell inner membrane and peripheral membrane protein which belongs to theshort-chain dehydrogenases/reductases (SDR) family and FabI subfamily. Microorganisms produce many kinds of antibiotics which function in an antagonistic capacity in nature where they have much competition. Bacterial FAS provides essential fatty acids for use in the assembly of key cellular components. Among them, FABI is an enoyl-ACP...
TMPH-01747	FDXR Protein, Human, Recombinant (His & SUMO) Ferredoxin--NADP(+) reductase,NADPH:adrenodoxin oxi...	Human	E. coli
	Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. FDXR Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 61.6 kDa and the accession number is P22570.
TMPY-02519	BLVRB Protein, Human, Recombinant (His) HEL-S-10,biliverdin reductase B,FLR,BVRB,SDR43U1	Human	E. coli
	Biliverdin reductase (hBVR) is a serine/threonine kinase that catalyzes reduction of the heme oxygenase (HO) activity product, biliverdin, to bilirubin. BVR consists of an N-terminal dinucleotide-binding domain (Rossmann-fold) and a C-terminal domain that contains a six-stranded β-sheet that is flanked on one face by several α-helices. The C-terminal and N-terminal domains interact extensively, forming the active site cleft at their interface. Biliverdin reductase (BVR) catalyzes the last step i...
TMPH-02498	AKR1C3 Protein, Mouse, Recombinant (His & Myc) Aldo-keto reductase family 1 member C13	Mouse	E. coli
	Catalyzes the dehydrogenation of 17-beta-hydroxysteroids. May also exhibit significant activity with a variety of cyclic and alicyclic alcohols. Uses both NAD and NADP, but the activity is much greater with NAD than with NADP. AKR1C3 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 44.5 kDa and the accession number is Q8VC28.
TMPH-03408	NirK Protein, Rhizobium sullae, Recombinant (His) nirK,Cu-NIR,Copper-containing nitrite reductase	Rhizobium sullae	E. coli
	NirK Protein, Rhizobium sullae, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40.8 kDa and the accession number is Q60214.
TMPY-02527	p53R2 Protein, Human, Recombinant (His) P53R2,MTDPS8A,MTDPS8B,ribonucleotide reductase M2 B...	Human	E. coli
	Ribonucleoside reductase subunit M2B, also known as RRM2B or p53R2, is an enzyme belonging to the iron-dependent ribonucleotide reductase (RNR) enzyme family which is essential for DNA synthesis. Ribonucleotide reductase (RNR) is an enzyme that catalyzes the formation of deoxyribonucleotides from ribonucleotides and plays a critical role in regulating the total rate of DNA synthesis so that DNA to cell mass is maintained at a constant ratio during cell division and DNA repair. RRM2B is a phospho...
TMPH-01748	CYPOR Protein, Human, Recombinant (GST) NADPH--cytochrome P450 reductase,P450R,CPR,POR,CYPO...	Human	E. coli
	This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. CYPOR Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 102.9 kDa and the accession number is P16435.
TMPH-02801	CYPOR Protein, Mouse, Recombinant (His) CYPOR,P450R,CPR,NADPH--cytochrome P450 reductase,PO...	Mouse	E. coli
	CYPOR Protein, Mouse, Recombinant (His) is expressed in E. coli.
TMPH-00553	Fructose 5-dehydrogenase [NADP(+)] Protein, Erwinia citreus, Recombinant (His & KSI) Fructose 5-dehydrogenase [NADP(+)],5-ketofructose reduct...	Erwinia citreus	E. coli
	Fructose 5-dehydrogenase [NADP(+)] Protein, Erwinia citreus, Recombinant (His & KSI) is expressed in E. coli.
TMPH-02476	HMGCR Protein, Mouse, Recombinant (His) Hmgcr,3-hydroxy-3-methylglutaryl-coenzyme A reductase	Mouse	E. coli
	Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.4 kDa and the accession number is Q01237.
TMPH-00097	AtAER Protein, Arabidopsis thaliana, Recombinant (His & SUMO) NADPH-dependent oxidoreductase 2-alkenal reduct...	Arabidopsis thaliana	E. coli
	AtAER Protein, Arabidopsis thaliana, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 54.1 kDa and the accession number is Q39172.
TMPH-00098	AtAER Protein, Arabidopsis thaliana, Recombinant P1-ZCr,NADPH-azodicarbonyl/quinone reductase,NADPH-...	Arabidopsis thaliana	E. coli
	AtAER Protein, Arabidopsis thaliana, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 38.1 kDa and the accession number is Q39172.
TMPJ-00955	MDH1 Protein, Human, Recombinant (His) Cytosolic Malate Dehydrogenase,MDH1,MDHA,Diiodophenylpyruvat...	Human	E. coli
	Malate Dehydrogenase, Cytoplasmic (MDH1) is an enzyme which belongs to the MDH Type 2 sub-family of LDH/MDH superfamily. MDH1 is involved in the Citric Acid Cycle that catalyzes the conversion of Malate into Oxaloacetate (using NAD+) and vice versa. MDH1 should not be confused with Malic Enzyme, which catalyzes the conversion of Malate to Pyruvate, producing NADPH. MDH1 also participates in Gluconeogenesis, the synthesis of Glucose from smaller molecules. Pyruvate in the mitochondria is acted up...
TMPY-02271	TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His) thioredoxin reductase 1,TR1,TXNR,TR,TRXR1,GRIM-12	Human	E. coli
	Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidative damage. We investigated the association between TXNRD1 polymorphisms and ATDH susceptibility. Moreover, TXNRD1 is an essential selenium-containing enzyme involved in detoxification of reactive oxygen species (ROS) and redox signaling. And genetic variations in TXNRD1 favor th...
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重组蛋白

Adrenodoxin reductase Protein, Bovine, Recombinant (His)

Cat.No: TMPH-00288

Species: Bovine

Expression System: P. pastoris (Yeast)

Dihydrofolate reductase Protein, Human, Recombinant (His)

Cat.No: TMPH-01224

Species: Human

Expression System: E. coli

NAD(P)H-flavin reductase Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00658

Species: E. coli

Expression System: E. coli

Adrenodoxin reductase Protein, Bovine, Recombinant (E. coli, His)

Cat.No: TMPH-00287

Species: Bovine

Expression System: E. coli

FMN reductase Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00625

Species: E. coli

Expression System: Baculovirus Insect Cells

Dihydrofolate reductase Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00608

Species: E. coli

Expression System: E. coli

Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc)

Cat.No: TMPH-03535

Species: Staphylococcus aureus

Expression System: E. coli

Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His)

Cat.No: TMPH-03581

Species: Staphylococcus epidermidis

Expression System: E. coli

TMAO reductase 1 Protein, E. coli O157:H7, Recombinant (His & Myc)

Cat.No: TMPH-00683

Species: E. coli

Expression System: E. coli

HMGCR Protein, Human, Recombinant (His)

Cat.No: TMPH-00007

Species: Human

Expression System: E. coli

RRM2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00937

Species: Human

Expression System: HEK293 Cells

GLXR Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02686

Species: Mouse

Expression System: E. coli

DHCR7 Protein, Bovine, Recombinant (His)

Cat.No: TMPH-00218

Species: Bovine

Expression System: E. coli

MTR Protein, Mycobacterium tuberculosis, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-03020

Species: Mycobacterium tuberculosis

Expression System: E. coli

NrdD Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00578

Species: E. coli

Expression System: E. coli

QDPR Protein, Human, Recombinant (His)

Cat.No: TMPJ-00813

Species: Human

Expression System: HEK293 Cells

PYCR Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)

Cat.No: TMPH-03196

Species: Mycobacterium tuberculosis

Expression System: E. coli

BLVRA Protein, Human, Recombinant (His)

Cat.No: TMPJ-01009

Species: Human

Expression System: E. coli

Neuroglobin Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01761

Species: Human

Expression System: E. coli

NirS Protein, Pseudomonas stutzeri, Recombinant (His & Myc)

Cat.No: TMPH-03191

Species: Pseudomonas stutzeri

Expression System: E. coli

ENR Protein, Mycobacterium tuberculosis, Recombinant (His)

Cat.No: TMPH-03008

Species: Mycobacterium tuberculosis

Expression System: E. coli

GMPR Protein, Human, Recombinant (His)

Cat.No: TMPY-03617

Species: Human

Expression System: E. coli

FabG Protein, E. coli, Recombinant (His & Myc)

Cat.No: TMPH-00564

Species: E. coli

Expression System: E. coli

MSRB3 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00354

Species: Human

Expression System: HEK293 Cells

MSRB3 Protein, Human, Recombinant (His)

Cat.No: TMPY-00538

Species: Human

Expression System: HEK293 Cells

PYCR1 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02174

Species: Human

Expression System: E. coli

CBR3 Protein, Human, Recombinant (His)

Cat.No: TMPY-03867

Species: Human

Expression System: E. coli

TXNRD2 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02198

Species: Human

Expression System: E. coli

NQO1 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02797

Species: Mouse

Expression System: P. pastoris (Yeast)

FabI Protein, S. aureus, Recombinant (His & SUMO)

Cat.No: TMPH-03536

Species: Staphylococcus aureus

Expression System: E. coli

Myoglobin Protein, Mouse, Recombinant (E. coli, His & Myc)

Cat.No: TMPH-02794

Species: Mouse

Expression System: E. coli

AKR1B1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02438

Species: Human

Expression System: E. coli

AKR1A1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02461

Species: Human

Expression System: E. coli

RRM1 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-03287

Species: Human

Expression System: Baculovirus Insect Cells

NarG Protein, E. coli, Recombinant (His & Myc)

Cat.No: TMPH-00725

Species: E. coli

Expression System: E. coli

Myoglobin Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02795

Species: Mouse

Expression System: HEK293 Cells

Enoyl-ACP Reductase Protein, E. coli, Recombinant (His)

Cat.No: TMPY-01812

Species: E. coli

Expression System: E. coli

FDXR Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01747

Species: Human

Expression System: E. coli

BLVRB Protein, Human, Recombinant (His)

Cat.No: TMPY-02519

Species: Human

Expression System: E. coli

AKR1C3 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02498

Species: Mouse

Expression System: E. coli

NirK Protein, Rhizobium sullae, Recombinant (His)

Cat.No: TMPH-03408

Species: Rhizobium sullae

Expression System: E. coli

p53R2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02527

Species: Human

Expression System: E. coli

CYPOR Protein, Human, Recombinant (GST)

Cat.No: TMPH-01748

Species: Human

Expression System: E. coli

CYPOR Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02801

Species: Mouse

Expression System: E. coli

Fructose 5-dehydrogenase [NADP(+)] Protein, Erwinia citreus, Recombinant (His & KSI)

Cat.No: TMPH-00553

Species: Erwinia citreus

Expression System: E. coli

HMGCR Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02476

Species: Mouse

Expression System: E. coli

AtAER Protein, Arabidopsis thaliana, Recombinant (His & SUMO)

Cat.No: TMPH-00097

Species: Arabidopsis thaliana

Expression System: E. coli

AtAER Protein, Arabidopsis thaliana, Recombinant

Cat.No: TMPH-00098

Species: Arabidopsis thaliana

Expression System: E. coli

MDH1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00955

Species: Human

Expression System: E. coli

TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His)

Cat.No: TMPY-02271

Species: Human

Expression System: E. coli

--------- 更多 ---------

Cat. No.	Product Name	Target	Signaling Pathways
T12488	Pitavastatin D4 NK-104 D4	Others	Others
	Pitavastatin D4 is deuterium labeled Pitavastatin. Pitavastatin is a potent inhibitor of HMG-CoA reductase.
T10916	Cycloguanil D6 Chlorguanide triazine D6	Others	Others
	Cycloguanil D6 is a dihydrofolate reductase inhibitor, deuterium-labeled Cycloguanil.
T10915	Cycloguanil D6 Nitrate Chlorguanide triazine D6 Nitrate	Others	Others
	Cycloguanil D6 Nitrate is a dihydrofolate reductase inhibitor, deuterium-labeled Cycloguanil.
T12757	Rosuvastatin D3 Sodium	Others	Others
	Rosuvastatin D3 Sodium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM).
T19551	Rosuvastatin D6 Calcium	Others	Others
	Rosuvastatin D6 Calcium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM).
T12759	Rosuvastatin D6 Sodium	Others	Others
	Rosuvastatin D6 Sodium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM).
T11306	Fluvastatin D6 sodium XU 62-320 (D6)	Others	Others
	Fluvastatin sodium is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM.Fluvastatin D6 sodium is deuterium labeled Fluvastatin sodium.
T10128	(3S,5R)-Fluvastatin D6 sodium (3S,5R)-XU 62-320 D6	Others	Others
	(3S,5R)-Fluvastatin D6 sodium is the deuterium-labeled (3S,5R)-Fluvastatin sodium. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor (IC50: 8 nM).
TMIJ-0496	Lovastatin-d3
	Lovastatin-d3 是 Lovastatin 的氘代化合物。Lovastatin 的 CAS 号为 75330-75-5。Lovastatin是一种 HMG-CoA 还原酶抑制剂，用于降低胆固醇。
TMIJ-0225	Finasteride-d9
	Finasteride-d9 是 Finasteride 的氘代化合物。Finasteride 的 CAS 号为 98319-26-7。Finasteride 是 5α-还原酶的竞争性抑制剂，对 II 型 5α-还原酶的IC50为 4.2 nM，对 II 型 5α-还原酶的亲和力是 I 型酶的 100 倍。它可用于研究前列腺增生和雄激素性脱发。
TMIJ-0265	Homovanillic Acid-13C-d3
	Homovanillic Acid-13C-d3 是 Homovanillic Acid 的 13C 和氘代化合物。Homovanillic Acid 的 CAS 号为 306-08-1。Homovanillic acid 是一种多巴胺代谢物，它与乳糜泻、生长激素缺乏、芳香族氨基酸脱羧酶缺乏症以及脂联素还原酶缺乏症相关。
TMIH-0242	Fluvastatin-d6 Sodium Salt
	Fluvastatin-d6 Sodium Salt 是 Fluvastatin Sodium Salt 的氘代化合物。Fluvastatin Sodium Salt 的 CAS 号为 93957-55-2。Fluvastatin sodium salt 是羟甲基戊二酰辅酶 A 还原酶的竞争性抑制剂，IC50为 8 nM。它通过依赖 Nrf2 的抗氧化通路保护血管平滑肌细胞免受氧化应激，是一种常用的降胆固醇剂。
TMIJ-0119	Pitavastatin-d4 Sodium Salt
	Pitavastatin-d4 Sodium Salt 是 Pitavastatin Sodium Salt 的氘代化合物。Pitavastatin Sodium Salt 的 CAS 号为 574705-92-3。
TMID-0057	(4-Hydroxy-3-methoxyphenyl)acetic-2,2-d2 Acid
	(4-Hydroxy-3-methoxyphenyl)acetic-2,2-d2 Acid 是 (4-Hydroxy-3-methoxyphenyl)acetic Acid 的氘代化合物。(4-Hydroxy-3-methoxyphenyl)acetic Acid 的 CAS 号为 306-08-1。Homovanillic acid 是一种多巴胺代谢物，它与乳糜泻、生长激素缺乏、芳香族氨基酸脱羧酶缺乏症以及脂联素还原酶缺乏症相关。
TMIH-0504	Rosuvastatin-d6 Calcium Salt
	Rosuvastatin-d6 Calcium Salt 是 Rosuvastatin Calcium Salt 的氘代化合物。Rosuvastatin Calcium Salt 的 CAS 号为 147098-20-2。Rosuvastatin calcium 是肝羟甲基戊二酰辅酶 A 还原酶的选择性和竞争性抑制剂，具有抗血脂活性。它降低成熟 hERG 的表达以及热休克蛋白 70 与 hERG 蛋白的相互作用，还降低低密度脂蛋白胆固醇、甘油三酯和 C-反应蛋白水平。它阻断人类醚-a-go-go相关基因电流，延迟心脏复极化，来延长动作电位持续时间和校正 QT 间期间隔。
TMID-0041	Menaquinone-9-d7 Vitamin K2-MK9-d7
	Menaquinone-9-d7 是 Menaquinone-9 的氘代化合物。Menaquinone-9 的 CAS 号为 523-39-7。Menaquinone 9 (MK-9) 是一种维生素 K2 类似物，已在包括大肠杆菌在内的各种细菌中发现。Menaquinone 9 对紫外线敏感，可与细菌电子传输链的一种成分可溶性硝酸还原酶结合。
TMIH-0457	Proguanil-d6 HCl
	Proguanil-d6 HCl 是 Proguanil HCl 的氘代化合物。Proguanil HCl 的 CAS 号为 637-32-1。Proguanil hydrochloride 是一种双胍类抗疟疾剂，在体内代谢形成环胍。它还是一种二氢叶酸还原酶抑制剂。
TMIJ-0040	17alpha-Estradiol-2,4-d2
	17alpha-Estradiol-2,4-d2 是 17alpha-Estradiol 的氘代化合物。17alpha-Estradiol 的 CAS 号为 57-91-0。17α-Estradiol 是一种雌性激素，可抑制5α-reductase，在雄原性脱发的研究中有潜力。

同位素标记化合物

Pitavastatin D4

Cat.No: T12488

Synonym: NK-104 D4

Target: Others

Cat.No: T10916

Synonym: Chlorguanide triazine D6

Target: Others

Cycloguanil D6 Nitrate

Cat.No: T10915

Synonym: Chlorguanide triazine D6 Nitrate

Target: Others

Rosuvastatin D3 Sodium

Cat.No: T12757

Target: Others

Rosuvastatin D6 Calcium

Cat.No: T19551

Target: Others

Rosuvastatin D6 Sodium

Cat.No: T12759

Target: Others

Fluvastatin D6 sodium

Cat.No: T11306

Synonym: XU 62-320 (D6)

Target: Others

(3S,5R)-Fluvastatin D6 sodium

Cat.No: T10128

Synonym: (3S,5R)-XU 62-320 D6

Target: Others

Cat.No: TMIJ-0496

Cat.No: TMIJ-0225

Homovanillic Acid-13C-d3

Cat.No: TMIJ-0265

Fluvastatin-d6 Sodium Salt

Cat.No: TMIH-0242

Pitavastatin-d4 Sodium Salt

Cat.No: TMIJ-0119

(4-Hydroxy-3-methoxyphenyl)acetic-2,2-d2 Acid

Cat.No: TMID-0057

Rosuvastatin-d6 Calcium Salt

Cat.No: TMIH-0504

Menaquinone-9-d7

Cat.No: TMID-0041

Synonym: Vitamin K2-MK9-d7

Proguanil-d6 HCl

Cat.No: TMIH-0457

17alpha-Estradiol-2,4-d2

Cat.No: TMIJ-0040

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