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Targets Recommended: Others

218

抑制剂 & 化合物

35

天然产物

1

化合物库

32

重组蛋白

3

同位素标记化合物

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Cat. No. Product Name
L9700 内质网应激化合物库

193 compounds
193 个内质网应激相关的化合物集合,可用于高通量和高内涵筛选;

化合物库

内质网应激化合物库
Cat.No: L9700
Compounds: 193
Cat. No. Product Name Target Signaling Pathways
T20019 Malachite green

Solid Green O,Solid Green Crystals O

Others Others
Malachite green (Solid Green Crystals O) 是一种 N-甲基化二氨基三苯基甲烷染料,可用于着色。
T9050 AG-270

Others; Methionine Adenosyltransferase (MAT) Chromatin/Epigenetic; Others
AG-270 是一种可逆的、非竞争性的、具有口服活性的MAT2A 变构抑制剂(IC50:14 nM)。
T12695 RBN-2397

PARP Chromatin/Epigenetic; DNA Damage/DNA Repair
RBN-2397 是一种有效的、选择性的、具有口服活性的跨物种 NAD+ 竞争性 PARP7 抑制剂,IC50 小于 3 nM。它选择性结合 PARP7 ,Kd 为0.001 μM,可恢复干扰素 I 型信号转导,有用于晚期或转移性实体肿瘤的研究潜力。
T6796 CB-5083

CB5083,CB 5083

p97 Ubiquitination
CB-5083 是一种有效的、选择性的、可口服的 p97 AAA ATPase 抑制剂,IC50为 11 nM。
T13044 Mevociclib

SY-1365

CDK Cell Cycle/Checkpoint
Mevociclib (SY-1365) 是一种高效选择性 CDK7抑制剂,Ki 值为 17.4 nM。它具有抗血液肿瘤和侵袭性实体肿瘤作用,有抗增殖和凋亡活性。
T9705 TL-895

BTK Angiogenesis; Tyrosine Kinase/Adaptors
TL-895 是口服有效的,ATP 竞争性的,以及高度选择性和不可逆的BTK 抑制剂,IC50和Ki 分别为 1.5 nM 和 11.9 nM。TL-895在 JAKi 复发/难治性骨髓纤维化、急性髓系白血病、COVID-19 和癌症方面有研究的价值。
T9756 AZD-9574

PARP Chromatin/Epigenetic; DNA Damage/DNA Repair
AZD-9574 是 SSB 位点的 PARP1 特异性抑制剂。 AZD-9574 具有抗癌活性,可用于 HRD+ 乳腺癌和晚期实体恶性肿瘤的研究。
T9430 Venadaparib

NOV140101,IDX-1197

PARP Chromatin/Epigenetic; DNA Damage/DNA Repair
Venadaparib (NOV140101) 是一种选择性和具有口服活性的 PARP 抑制剂,对 PARP1和 PARP2的 IC50分别为 1.4 和 1.0 nM。它可防止 DNA 单链断裂 (SSB) 的修复,可研究实体瘤。
T7318 Elimusertib

BAY-1895344

ATM/ATR DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
Elimusertib (BAY-1895344) 是一种可口服的选择性ATR 抑制剂,IC50值为 7 nM。它具有抗肿瘤活性,可研究实体瘤和淋巴瘤。
T8327 ONO-7475

Trk receptor; TAM Receptor Tyrosine Kinase/Adaptors
ONO-7475 是一种选择性的、有效的、具有口服活性的Axl/Mer 抑制剂。它使 AXL 过表达的EGFR 突变型 NSCLC 细胞对 EGFR-TKIs 敏感,抑制耐药细胞的产生和耐药性的维持。它与 Osimertinib 联合使用,具有用于 EGFR 突变非小细胞肺癌的潜力。
T3124 Carbendazim

Bavistin,Carbendazole,多菌灵,Mercarzole

Antifungal Microbiology/Virology
Carbendazim (Mercarzole) 是一种具有抗肿瘤活性的苯并咪唑衍生物,可用于癌症研究。它是一种口服广谱苯并咪唑杀菌剂,可作为真菌疾病研究的杀虫剂。
T2325 Neratinib

HKI-272,来那替尼

EGFR; HER Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Neratinib (HKI-272) 是一种酪氨酸激酶受体抑制剂,可以抑制 HER2 和 EGFR (IC50=59/92 nM),具有不可逆性和口服活性。Neratinib 具有抗肿瘤活性,可以用于治疗乳腺癌。
T6079 NVP-ADW742

ADW742,ADW,GSK 552602A

Apoptosis; IGF-1R Apoptosis; Tyrosine Kinase/Adaptors
NVP-ADW742 (ADW) 是一种具有口服活性,选择性的IGF-1R 酪氨酸激酶抑制剂,IC50为 0.17 μM。它抑制胰岛素受体,IC50为 2.8 μM,在肿瘤细胞中诱导多效性抗增殖/促凋亡。
T28475 Pyrazoloacridine

PD-115934,NSC 366140,NSC-366140,PD 115,934,PD 115934

Apoptosis; Topoisomerase Apoptosis; DNA Damage/DNA Repair
Pyrazoloacridine (PD 115934) 是一种核酸结合剂,在 K562 细胞中抑制 topo I 和 II 的活性,IC50 为 1.25 μM。 Pyrazoloacridine 具有抗癌活性。
T2134 Dorzolamide hydrochloride

MK507 hydrochloride,L671152 hydrochloride,MK-507 (L-671152) HCl,盐酸多佐胺,Dorzolamide HCl

Carbonic Anhydrase Metabolism
Dorzolamide hydrochloride (MK507 hydrochloride) 是一种碳酸酐酶carbonic anhydrase II 抑制剂,能够抑制红细胞CA-II(IC50:0.18 nM) 和CA-I(IC50:600 nM) 。
T124039 Achalensolide

Others Others
Achalensolide 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124039,CAS号为 87302-42-9。
T131396 Carnegine (Pectenine, N-Methylsalsolidine)

Others Others
Carnegine (Pectenine, N-Methylsalsolidine) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131396。
T125670 Phomopsolidone B

Others Others
Phomopsolidone B 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125670,CAS号为 1622333-85-0。
T131573 Isosalsolidine

Others Others
Isosalsolidine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131573。
T62604 Flunisolide hemihydrate

Others Others
Flunisolide hemihydrate 是一种皮质类固醇,是一种口服具有活力的糖皮质激素受体 (Glucocorticoid receptor) 激活剂,具有抗炎作用。Flunisolide hemihydrate 能够诱导嗜酸性粒细胞凋亡 (apoptosis),能够用于研究哮喘或鼻炎、炎症。
T123828 Phomopsolide B

Others Others
Phomopsolide B 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T123828,CAS号为 97529-84-5。
T2669 Berzosertib

VX-970,VE-822

ATM/ATR DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
Berzosertib (VE-822) 已用于研究卵巢肿瘤、卵巢浆液性肿瘤、成人实体瘤、晚期实体瘤和晚期实体瘤等治疗的试验。
T2357 GSK1059615

GSK 1059615,GSK-1059615

Apoptosis; PI3K; mTOR Apoptosis; PI3K/Akt/mTOR signaling
GSK1059615 是一种 PI3Kα/β/δ/γ可逆的抑制剂,同时也抑制 mTOR,IC50值分别为 0.4 nM/0.6 nM/2 nM/5 nM 和 12 nM,已用于研究淋巴瘤、实体瘤、子宫内膜癌、实体瘤癌和转移性乳腺癌治疗的试验。
T26978 CEP-40125

RXDX-107

DNA Alkylation DNA Damage/DNA Repair
CEP-40125 (RXDX-107) 是一种 DNA 烷基剂,可用于研究晚期实体瘤。
T0642 2-Methoxyphenothiazine

Factor Xa Metabolism
2-Methoxyphenothiazine 为淡黄色或淡灰色固体。
T2073 GSK2636771

GSK 2636771,GSK-2636771

PI3K PI3K/Akt/mTOR signaling
GSK2636771 是选择性的、口服有效的PI3Kβ抑制剂,Ki=0.89 nM,IC50=5.2 nM,比p110α和p110γ的选择性高900倍,比p110δ同种型的选择性高10倍。
T1601 Lomustine

CCNU,NSC 79037,洛莫司汀

Apoptosis; Others; DNA Alkylator/Crosslinker; DNA Alkylation; Autophagy Apoptosis; Autophagy; DNA Damage/DNA Repair; Others
Lomustine (NSC-79037) 是一种具有抗肿瘤活性的 DNA 烷化剂。
T2619 CH5132799

PI3K; mTOR PI3K/Akt/mTOR signaling
CH5132799 是一种选择性的 I 类PI3K 抑制剂。它能够抑制 PI3Kα,其 IC50=14 nM。
T36395 Trotabresib

CC-90010

Epigenetic Reader Domain Chromatin/Epigenetic
Trotabresib (CC-90010) 是一种具有口服活性的 BET 抑制剂,可用于晚期实体瘤的研究。
T12433 PF-06952229

PF06952229

TGF-beta/Smad Stem Cells
PF-06952229 是 TGFβRI 的选择性抑制剂。 PF-06952229 可用于治疗实体瘤,特别是转移性乳腺癌的研究。
T71137 Simmitecan hydrochloride

Topoisomerase DNA Damage/DNA Repair
Simmitecan hydrochloride 是一种喜树碱衍生物,是一种拓扑异构酶 I 抑制剂,具有抗癌活性,可用于研究是实体瘤。
T2113 PHA-793887

PHA 793887,PHA793887

Apoptosis; CDK Apoptosis; Cell Cycle/Checkpoint
PHA-793887 是一种ATP 竞争性的CDK 抑制剂,可抑制 Cdk2、Cdk1、Cdk4 和 Cdk9 的活性,IC50值分别为 8 nM、60 nM、62 nM 和 138 nM,同时可抑制糖原合酶激酶 3β,IC50值为 79 nM。
T7708 DL-Buthionine-(S,R)-sulfoximine

Butionine sulfoximine,丁基硫,NSC 381100,D,L-Buthionine-(S,R)-sulfoximine

Others; Ferroptosis Apoptosis; Others
DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) 是 γ-谷氨酰半胱氨酸合成酶的抑制剂,用于治疗实体瘤。
T76706 Varlilumab

CDX-1127

TNF Apoptosis
Varlilumab (CDX-1127) 是一种新型的人 IgG1 抗 CD27 单克隆抗体。Varlilumab 具有抗肿瘤活性,可用于研究晚期实体肿瘤。
T15009 Elacytarabine

5'-Oleoyl cytosine arabinoside,5'-O-(Elaidoyl) 1-beta-D-arabinofuranosylcytosine,5'-Oleoyl cytarabine,艾西拉滨,CP 4055

Others Others
Elacytarabine (M7594 0037) 是核苷类似物阿糖胞苷的一种脂质缀合衍生物。Elacytarabine (M7594 0037) (CP 4055) 是一种抗肿瘤药物,在实体瘤中具有细胞毒性。
T79157 Pimicotinib

ABSK021,ABSK-021

c-Fms; Others Others; Tyrosine Kinase/Adaptors
Pimicotinib (ABSK021) 为一种有效的 CSF1R 抑制剂,具抗肿瘤活性,可用于研究晚期实体瘤。
T17159 Treosulfan

NSC 39069,曲奥舒凡,Treosulphan

DNA Alkylator/Crosslinker; DNA Alkylation DNA Damage/DNA Repair
Treosulfan (Treosulphan) 是一种双功能的烷化剂,对卵巢癌及其他的实体瘤都有抑制效果。
T68144 Spiroplatin

Others Others
Spiroplatin(TNO-6)是一种新型含铂类似物,具有抗肿瘤活性,常用用于研究实体肿瘤。
T9901A-002 Enoblituzumab

MGA271,TJ-271

Others Others
Enoblituzumab 是一种人源化 IgG1κ 单克隆抗体,可以识别人 B7-H3 蛋白 ,可用于研究非小细胞肺癌 (NSCLC)等实体肿瘤。
T71924L AC 7739

Microtubule Associated Cytoskeletal Signaling
AC 7739 是一种微管蛋白结合剂,具有抗癌抗肿瘤活性,抑制晚期实体瘤和原位移植肿瘤。
T9929 Ramucirumab

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
Ramucirumab 是一种人 VEGFR-2 拮抗剂,具有抗实体瘤活性。它是人源化单克隆抗体,能够与 VEGFR-2 结合,阻碍 VEGFR 配体 VEGF-A,VEGF-C 和 VEGF-D 结合。
T76795 Xentuzumab

BI 836845

Akt; IGF-1R Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
Xentuzumab (BI836845) 是人源化IGF 配体的重组单克隆抗体,抑制 IGF1 和 IGF2 促生长信号传导,抑制 AKT 的激活,可用于研究实体肿瘤。
T77138 Ragifilimab

INCAGN-01876,INCAGN-1876,CM-701

TNF Apoptosis
Ragifilimab (INCAGN-1876),一种针对糖皮质激素诱导的TNFR相关蛋白(GITR)的单克隆抗体激动剂,适用于晚期或转移性实体瘤的研究。
T63260 Snail/HDAC-IN-1

Apoptosis; Antifungal Apoptosis; Microbiology/Virology
Snail/HDAC-IN-1是一种Snail/HDAC 抑制剂剂,具有抗菌抗癌活性, 可降低Snail蛋白的表达,诱导细胞凋亡,可用于研究实体肿瘤。
T2699 BMS 777607

BMS777607,BMS-777607,BMS 817378

c-Met/HGFR; TAM Receptor Tyrosine Kinase/Adaptors
BMS 777607 (BMS 817378) 是 Met-related 抑制剂,能够抑制 c-Met (IC50:3.9 nM),Axl (IC50:1.1 nM),Ron (IC50:1.8 nM) 和 Tyro3 (IC50:4.3 nM) 的活性。
T40199 Tulmimetostat

CPI-0209

Histone Methyltransferase Chromatin/Epigenetic
Tulmimetostat (CPI-0209) 是一种具有口服活性的 EZH1/EZH2 抑制剂。Tulmimetostat 有抗肿瘤活性,用于研究卵巢癌和晚期实体瘤。
T2503 PAC-1

Procaspase activating compound 1

Apoptosis; Caspase; Autophagy Apoptosis; Autophagy; Proteases/Proteasome
PAC-1 (Procaspase activating compound 1) 是一种 procaspase-3激活剂,诱导癌细胞凋亡,EC50为 2.08 μM,可用于研究淋巴瘤、黑色素瘤、实体瘤、乳腺癌和胸癌等治疗的试验。
T9901A-008 Volociximab

Eos 200-4,M200

Integrin Cytoskeletal Signaling
Volociximab (M200) 是一种靶向 α5β1 整合素的 IgG4 单克隆抗体 ,具有抗血管生成、抗肿瘤和抗癌活性,可抑制兔子 VX2 肿瘤的生长,用于研究实体瘤。
T13519 6-Aminochrysene

6-Chrysenamine

Others Others
6-Aminochrysene (6-Chrysenamine) 是几种实体实验性肿瘤生长的抑制剂,可用于脾肿大、乳腺癌和骨髓性白血病的研究。
T24051 Exisulind

Sulindac sulfone,CP248

Apoptosis; PKA Apoptosis; Tyrosine Kinase/Adaptors
Exisulind (CP248) 通过激活蛋白激酶 G (PKG) 诱导细胞凋亡。 Exisulind 在实体瘤和血液癌细胞系中表现出抗肿瘤活性,并且是结肠癌、前列腺癌、膀胱癌、乳腺癌和肺癌啮齿动物模型中肿瘤生长的抑制剂。

化合物

Malachite green
Cat.No: T20019
Synonym: Solid Green O,Solid Green Crystals O
Target: Others
AG-270
Cat.No: T9050
Synonym:
Target: Others, Methionine Adenosyltransferase (MAT)
RBN-2397
Cat.No: T12695
Synonym:
Target: PARP
CB-5083
Cat.No: T6796
Synonym: CB5083,CB 5083
Target: p97
Mevociclib
Cat.No: T13044
Synonym: SY-1365
Target: CDK
TL-895
Cat.No: T9705
Synonym:
Target: BTK
AZD-9574
Cat.No: T9756
Synonym:
Target: PARP
Venadaparib
Cat.No: T9430
Synonym: NOV140101,IDX-1197
Target: PARP
Elimusertib
Cat.No: T7318
Synonym: BAY-1895344
Target: ATM/ATR
ONO-7475
Cat.No: T8327
Synonym:
Target: Trk receptor, TAM Receptor
Carbendazim
Cat.No: T3124
Synonym: Bavistin,Carbendazole,多菌灵,Mercarzole
Target: Antifungal
Neratinib
Cat.No: T2325
Synonym: HKI-272,来那替尼
Target: EGFR, HER
NVP-ADW742
Cat.No: T6079
Synonym: ADW742,ADW,GSK 552602A
Target: Apoptosis, IGF-1R
Pyrazoloacridine
Cat.No: T28475
Synonym: PD-115934,NSC 366140,NSC-366140,PD 115,934,PD 115934
Target: Apoptosis, Topoisomerase
Dorzolamide hydrochloride
Cat.No: T2134
Synonym: MK507 hydrochloride,L671152 hydrochloride,MK-507 (L-671152) HCl,盐酸多佐胺,Dorzolamide HCl
Target: Carbonic Anhydrase
Achalensolide
Cat.No: T124039
Synonym:
Target: Others
Carnegine (Pectenine, N-Methylsalsolidine)
Cat.No: T131396
Synonym:
Target: Others
Phomopsolidone B
Cat.No: T125670
Synonym:
Target: Others
Isosalsolidine
Cat.No: T131573
Synonym:
Target: Others
Flunisolide hemihydrate
Cat.No: T62604
Synonym:
Target: Others
Phomopsolide B
Cat.No: T123828
Synonym:
Target: Others
Berzosertib
Cat.No: T2669
Synonym: VX-970,VE-822
Target: ATM/ATR
GSK1059615
Cat.No: T2357
Synonym: GSK 1059615,GSK-1059615
Target: Apoptosis, PI3K, mTOR
CEP-40125
Cat.No: T26978
Synonym: RXDX-107
Target: DNA Alkylation
2-Methoxyphenothiazine
Cat.No: T0642
Synonym:
Target: Factor Xa
GSK2636771
Cat.No: T2073
Synonym: GSK 2636771,GSK-2636771
Target: PI3K
Lomustine
Cat.No: T1601
Synonym: CCNU,NSC 79037,洛莫司汀
Target: Apoptosis, Others, DNA Alkylator/Crosslinker, DNA Alkylation, Autophagy
CH5132799
Cat.No: T2619
Synonym:
Target: PI3K, mTOR
Trotabresib
Cat.No: T36395
Synonym: CC-90010
Target: Epigenetic Reader Domain
PF-06952229
Cat.No: T12433
Synonym: PF06952229
Target: TGF-beta/Smad
Simmitecan hydrochloride
Cat.No: T71137
Synonym:
Target: Topoisomerase
PHA-793887
Cat.No: T2113
Synonym: PHA 793887,PHA793887
Target: Apoptosis, CDK
DL-Buthionine-(S,R)-sulfoximine
Cat.No: T7708
Synonym: Butionine sulfoximine,丁基硫,NSC 381100,D,L-Buthionine-(S,R)-sulfoximine
Target: Others, Ferroptosis
Varlilumab
Cat.No: T76706
Synonym: CDX-1127
Target: TNF
Elacytarabine
Cat.No: T15009
Synonym: 5'-Oleoyl cytosine arabinoside,5'-O-(Elaidoyl) 1-beta-D-arabinofuranosylcytosine,5'-Oleoyl cytarabine,艾西拉滨,CP 4055
Target: Others
Pimicotinib
Cat.No: T79157
Synonym: ABSK021,ABSK-021
Target: c-Fms, Others
Treosulfan
Cat.No: T17159
Synonym: NSC 39069,曲奥舒凡,Treosulphan
Target: DNA Alkylator/Crosslinker, DNA Alkylation
Spiroplatin
Cat.No: T68144
Synonym:
Target: Others
Enoblituzumab
Cat.No: T9901A-002
Synonym: MGA271,TJ-271
Target: Others
AC 7739
Cat.No: T71924L
Synonym:
Target: Microtubule Associated
Ramucirumab
Cat.No: T9929
Synonym:
Target: VEGFR
Xentuzumab
Cat.No: T76795
Synonym: BI 836845
Target: Akt, IGF-1R
Ragifilimab
Cat.No: T77138
Synonym: INCAGN-01876,INCAGN-1876,CM-701
Target: TNF
Snail/HDAC-IN-1
Cat.No: T63260
Synonym:
Target: Apoptosis, Antifungal
BMS 777607
Cat.No: T2699
Synonym: BMS777607,BMS-777607,BMS 817378
Target: c-Met/HGFR, TAM Receptor
Tulmimetostat
Cat.No: T40199
Synonym: CPI-0209
Target: Histone Methyltransferase
PAC-1
Cat.No: T2503
Synonym: Procaspase activating compound 1
Target: Apoptosis, Caspase, Autophagy
Volociximab
Cat.No: T9901A-008
Synonym: Eos 200-4,M200
Target: Integrin
6-Aminochrysene
Cat.No: T13519
Synonym: 6-Chrysenamine
Target: Others
Exisulind
Cat.No: T24051
Synonym: Sulindac sulfone,CP248
Target: Apoptosis, PKA
Cat. No. Product Name Target Signaling Pathways
T19278 Dicaprylyl carbonate

碳酸二辛酯,Dimethyl carbonate

Others Others
Dicaprylyl carbonate (Dimethyl carbonate) 是植物来源的固体脂肪,是干燥润肤剂。它具有强大的皮肤相容性和全面的性能,如防晒滤光片的增溶和分散能力。
TN1035 Irisolidone

尼泊尔鸢尾异黄酮,葛花苷元

IL Receptor; NF-κB; Chloride channel Immunology/Inflammation; Membrane transporter/Ion channel; NF-κB
Irisolidone 是葛根花中的一种异黄酮,具有较强的保肝活性。它是一种有效的体积调节阴离子通道 (VRAC) 电流抑制剂,有高效阻断作用,IC50 为 5-13 μM。
T75459 Canadensolide

Others Others
Canadensolide 是一种 Penicillium canadense 的抗真菌代谢产物。
TN2641 15-Methoxypinusolidic acid

ERK; IL Receptor; p38 MAPK; Calcium Channel; NOS; NF-κB; COX; JNK; NMDAR; PPAR DNA Damage/DNA Repair; Immunology/Inflammation; MAPK; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB
15-Methoxypinusolidic acid has anti-inflammatory effects, it inhibits LPS-induced iNOS expression and NO production, independent on MAPK and NF-kappaB. 15-Methoxypinusolidic acid suppresses adipocyte differentiation through the inhibition of PPARgamma-dep
TL0014 Pinusolide

ERK; p38 MAPK; Calcium Channel; Lipoxygenase; PAFR; Caspase; JNK; AMPK Apoptosis; Chromatin/Epigenetic; GPCR/G Protein; MAPK; Membrane transporter/Ion channel; Metabolism; PI3K/Akt/mTOR signaling; Proteases/Proteasome
Pinusolide is a platelet activating factor ( PAF) antagonist, it may prove of therapeutic value in the treatment of hypotension, it has antileukemic potential, and could be used to treat neurodegenerative diseases. Pinusolide attenuates blockade of insulin signaling by enhancing IRS-1 tyrosine phosphorylation by the activating the AMPK pathway, indicates the targeting of AMPK represents a new therapeutic strategy for hyperglycemia-induced insulin resistance and type 2 diabetes.
T81131 Solidagolactone II

Solidagolactone II is a clerodane diterpene isolated from the plant Solidago virgaurea L.
T75576 Solidagonic acid

Others Others
Solidagonic acid 通过促进异常单极纺锤体向双极纺锤体的转变来抑制 HSET 运动活动。Solidagonic acid 抑制裂殖酵母细胞死亡,并使有丝分裂纺锤体从单极形态逆转为双极形态。Solidagonic acid 对 Lactuca sativaL. 和 Lolium multiflorumLam 的幼苗具有生长抑制活性。
T40576 (S)-Salsolidine

Others Others
(S)-Salsolidine, a chemical compound, functions as a weak inhibitor of monoamine oxidase (MAO), exhibiting an inhibition constant (K i ) of 63 μM. R enantiomer demonstrating a greater efficacy than (S)-Salsolidine, boasting a K i value of 26 μM compared to the S form.
TN4794 Pinusolidic acid

PAFR GPCR/G Protein
Pinusolidic acid shows a potent inhibitory effect on platelet activating factor (PAF) binding to rabbit platelets (IC50 = 2.3 x 10(-5) M, 7.48 +/- 2.11 micrograms/ml).
T8429 Salsolidine hydrochloride

6,7-DIMETHOXY-1-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE, 99

Salsolidine hydrochloride 在生命科学相关研究中具有广泛的应用。
T81130 Solidagolactone III

Solidagolactone III,一种从Solidago属植物中分离得到的活性化合物。
T5119 Dicyclo hexyl Phthalate

Others Others
Dicyclo hexyl Phthalate 是一种固体增塑剂。
T39007 3,4-Dimethoxybenzamide

Others Others
3,4-Dimethoxybenzamide 是分离自Streptoverticillium morookaense 固体培养物的酰胺。它是制备盐酸伊托必利的起始原料。
T19237 Cholesteryl oleate

胆固醇油酸酯,Oleoylcholesterol,Cholesterol Oleate,Cholesteryl cis-9-octadecenoate

Endogenous Metabolite Metabolism
Cholesteryl oleate (Cholesteryl cis-9-octadecenoate) 是胆固醇的酯化形式,可用于合成固体脂质纳米颗粒。
T4784 (S)-(-)-Phenylethanol

(S)-(-)-1-Phenylethanol,右旋1-苯乙醇,(-)-Methyl phenyl carbinol,(S)-(-)-sec-Phenylethyl alcohol

Others; Endogenous Metabolite Metabolism; Others
(S)-(-)-Phenylethanol ((-)-Methyl phenyl carbinol) 是内源性代谢产物的一种。
T5082 Calcium 2-hydroxy-4-(methylthio)butanoate

羟基蛋氨酸钙,calcium hydroxymethionine,2-Hydroxy-4-(methylthio)butyric acid calcium salt

Others; Endogenous Metabolite Metabolism; Others
Calcium 2-hydroxy-4-(methylthio)butanoate (Calcium 2-hydroxy-4-(calcium hydroxymethionine)) 是内源性代谢产物的一种。
T5724 Neogambogic acid

neo-gambogic acid,新藤黄酸

Apoptosis; Others; Antibacterial Apoptosis; Microbiology/Virology; Others
Neogambogic acid 是藤黄的有效成分,可诱导细胞凋亡并具有抗癌作用。它有效抑制耐甲氧西林的金黄色葡萄球菌。
T8733 Antrodin A

(2-氯苯基)二苯基甲醇,camphorataanhydride A

Others Others
Antrodin A (camphorataanhydride A) 是固体发酵樟脑菌菌丝体的一种主要活性成分。它能够增强肝脏的抗炎及抗氧化能力,维持肠道菌群的稳定,避免酒精对肝脏的损伤。
T2989 4-Hydroxybenzoic acid

p-hydroxybenzoic acid,para-Hydroxybenzoic acid,PHBA,对羟基苯甲酸,4-hydroxybenzoate

Endogenous Metabolite; Antibacterial Metabolism; Microbiology/Virology
4-Hydroxybenzoic acid (4-hydroxybenzoate) 是苯甲酸的酚衍生物,可抑制革兰氏阳性和革兰氏阴性菌,IC50值为160 μg/mL。
T4773 3-Ethoxy-3-oxopropanoic acid

Monoethyl malonic acid,Ethyl hydrogen malonate,丙二酸单乙酯

Others; Endogenous Metabolite Metabolism; Others
3-Ethoxy-3-oxopropanoic acid (Monoethyl malonic acid) 是内源性代谢产物的一种。
T0186 Docetaxel trihydrate

RP-56976 (Trihydrate),RP56976 (NSC 628503) Trihydrate,多西他赛三水合物

Apoptosis; BCL; Microtubule Associated Apoptosis; Cytoskeletal Signaling
Docetaxel trihydrate (RP-56976 Trihydrate) 是一种抗肿瘤试剂,抑制微管解聚的IC50值为 0.2 μM。它是紫杉醇的半合成类似物,能减弱 bcl-2 和 bcl-xL 基因表达的影响。它阻滞G2/M 细胞周期,导致细胞凋亡。
T6S0033 Crotonoside

巴豆苷;异鸟苷,巴豆苷,Isoguanosine,2-HYDROXYADENOSINE

Others; FLT; HDAC Angiogenesis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Others; Tyrosine Kinase/Adaptors
Crotonoside (Isoguanosine) 是从中草药巴豆中分离出来的一种天然产物。 它抑制 FLT3 和 HDAC3/6,有治疗急性髓性白血病 (AML)的研究潜力。
T3746 Dimethyl phthalate

邻苯二甲酸二甲酯,Solvanom,Avolin,Fermine,避蚊酯

Others Others
Dimethyl phthalate (Fermine) 是一种邻苯二甲酸酯 (PAEs),是一种已知的内分泌干扰物,也是一种普遍存在的污染物。它常作为增塑剂,赋予硬质聚氯乙烯 (PVC) 树脂以柔韧性。
T40519 Indicine N-oxide

(+)-Indicine N-oxide,Indicine N-oxide,NSC132319

Others Others
Indicine N-oxide (NSC 132319), a pyrrolizidine alkaloid, serves as an antitumor agent in pediatric cancer and solid tumors research.
T28428 PM-060184

Plocabulin,PM 060184

Others Others
PM-060184, a tubulin polymerisation inhibitor, is used potentially for the treatment of solid tumours and breast cancer.
TN6511 Tessaric acid

Tessaric acid has antifeedant and allelochemical effects. Tessaric acid derivatives induce G/M cell cycle arrest in human solid tumor cell lines.
T38395 Pyrrole-2-carboxaldehyde

Others Others
Pyrrole-2-carboxaldehyde exhibits distinctive vibrational and electronic properties which serve to validate its dimeric state in the solid phase and monomeric state in the solution phase.
TN4788 Pierreione B

mTOR PI3K/Akt/mTOR signaling
Pierreione B is an inhibitor of mTOR signaling with strong anticancer activity. Pierreione A and Pierreione B demonstrate solid tumor selectivity with minimal cytotoxicity.
T20001 Butyl benzoate

HSDB 2089,NSC 8474,Benzoic acid, butyl ester,AI3-00521,BRN 1867073

Butyl benzoate as an involatile solvent, for the sampling of isocyanates with silica gel solid-phase extraction. Butyl benzoate has been used as a preservative in commercial cosmetic lotions.
T75480 Guignardone K

Others Others
Guignardone K,一种二萜化合物,从内生真菌(Guignardia sp.)的固体培养物中分离出来,具有抗真菌活性。
T81660 Nocarimidazole A

Others Others
Nocarimidazole A,一种来源于海洋放线菌Nocardiopsis的白色无定形固体生物碱,具紫外线活性。
T71750 Quinolactacin A1

Others Others
Quinolactacin A1 是一种有效的乙酰胆碱酯酶 (AChE) 抑制剂,可从Penicillium citrinum 中得到。Quinolactacin A1 可用于阿尔茨海默病的研究。
T83110 Angulatin K

Angulatin K为Celastrus angulatus根皮中发现的天然倍半萜多元醇酯。
T29607 Acid Red 88

11391 Red,Eniacid Fast Red A,Peony,Red No. 506

Acid red 88 is an anionic dye with potentially useful photocatalytic research applications. Acid red 88 has been used to determine the effect of Au deposition on ZnO photocatalytic activity under visible light. Additionally, the photocatalyst Au-TiO2 was
T76119 Rennin

Others Others
Rennin(亦称Chymosin)是一种蛋白水解酶,与胃蛋白酶有关,其由部分动物胃细胞合成。该酶特异性针对其天然底物K-酪蛋白,在氨基酸残基105和106、苯丙氨酸与甲硫氨酸间的肽键处进行切割,使液态奶转化为半固体状,以便在胃中停留更久,广泛应用于奶酪生产中。

天然产物

Dicaprylyl carbonate
Cat.No: T19278
Synonym: 碳酸二辛酯,Dimethyl carbonate
Target: Others
Irisolidone
Cat.No: TN1035
Synonym: 尼泊尔鸢尾异黄酮,葛花苷元
Target: IL Receptor, NF-κB, Chloride channel
Canadensolide
Cat.No: T75459
Synonym:
Target: Others
15-Methoxypinusolidic acid
Cat.No: TN2641
Synonym:
Target: ERK, IL Receptor, p38 MAPK, Calcium Channel, NOS, NF-κB, COX, JNK, NMDAR, PPAR
Pinusolide
Cat.No: TL0014
Synonym:
Target: ERK, p38 MAPK, Calcium Channel, Lipoxygenase, PAFR, Caspase, JNK, AMPK
Solidagolactone II
Cat.No: T81131
Synonym:
Target:
Solidagonic acid
Cat.No: T75576
Synonym:
Target: Others
(S)-Salsolidine
Cat.No: T40576
Synonym:
Target: Others
Pinusolidic acid
Cat.No: TN4794
Synonym:
Target: PAFR
Salsolidine hydrochloride
Cat.No: T8429
Synonym: 6,7-DIMETHOXY-1-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE, 99
Target:
Solidagolactone III
Cat.No: T81130
Synonym:
Target:
Dicyclo hexyl Phthalate
Cat.No: T5119
Synonym:
Target: Others
3,4-Dimethoxybenzamide
Cat.No: T39007
Synonym:
Target: Others
Cholesteryl oleate
Cat.No: T19237
Synonym: 胆固醇油酸酯,Oleoylcholesterol,Cholesterol Oleate,Cholesteryl cis-9-octadecenoate
Target: Endogenous Metabolite
(S)-(-)-Phenylethanol
Cat.No: T4784
Synonym: (S)-(-)-1-Phenylethanol,右旋1-苯乙醇,(-)-Methyl phenyl carbinol,(S)-(-)-sec-Phenylethyl alcohol
Target: Others, Endogenous Metabolite
Calcium 2-hydroxy-4-(methylthio)butanoate
Cat.No: T5082
Synonym: 羟基蛋氨酸钙,calcium hydroxymethionine,2-Hydroxy-4-(methylthio)butyric acid calcium salt
Target: Others, Endogenous Metabolite
Neogambogic acid
Cat.No: T5724
Synonym: neo-gambogic acid,新藤黄酸
Target: Apoptosis, Others, Antibacterial
Antrodin A
Cat.No: T8733
Synonym: (2-氯苯基)二苯基甲醇,camphorataanhydride A
Target: Others
4-Hydroxybenzoic acid
Cat.No: T2989
Synonym: p-hydroxybenzoic acid,para-Hydroxybenzoic acid,PHBA,对羟基苯甲酸,4-hydroxybenzoate
Target: Endogenous Metabolite, Antibacterial
3-Ethoxy-3-oxopropanoic acid
Cat.No: T4773
Synonym: Monoethyl malonic acid,Ethyl hydrogen malonate,丙二酸单乙酯
Target: Others, Endogenous Metabolite
Docetaxel trihydrate
Cat.No: T0186
Synonym: RP-56976 (Trihydrate),RP56976 (NSC 628503) Trihydrate,多西他赛三水合物
Target: Apoptosis, BCL, Microtubule Associated
Crotonoside
Cat.No: T6S0033
Synonym: 巴豆苷;异鸟苷,巴豆苷,Isoguanosine,2-HYDROXYADENOSINE
Target: Others, FLT, HDAC
Dimethyl phthalate
Cat.No: T3746
Synonym: 邻苯二甲酸二甲酯,Solvanom,Avolin,Fermine,避蚊酯
Target: Others
Indicine N-oxide
Cat.No: T40519
Synonym: (+)-Indicine N-oxide,Indicine N-oxide,NSC132319
Target: Others
PM-060184
Cat.No: T28428
Synonym: Plocabulin,PM 060184
Target: Others
Tessaric acid
Cat.No: TN6511
Synonym:
Target:
Pyrrole-2-carboxaldehyde
Cat.No: T38395
Synonym:
Target: Others
Pierreione B
Cat.No: TN4788
Synonym:
Target: mTOR
Butyl benzoate
Cat.No: T20001
Synonym: HSDB 2089,NSC 8474,Benzoic acid, butyl ester,AI3-00521,BRN 1867073
Target:
Guignardone K
Cat.No: T75480
Synonym:
Target: Others
Nocarimidazole A
Cat.No: T81660
Synonym:
Target: Others
Quinolactacin A1
Cat.No: T71750
Synonym:
Target: Others
Angulatin K
Cat.No: T83110
Synonym:
Target:
Acid Red 88
Cat.No: T29607
Synonym: 11391 Red,Eniacid Fast Red A,Peony,Red No. 506
Target:
Rennin
Cat.No: T76119
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPK-00008 CCL5 Protein, Mouse, Recombinant (hFc)

D17S136E,RANTES,SCYA5,SIS-δ,Ccl5,SISd,eoCP,MuRantes,TCP228,S...

Mouse HEK293 Cells
The CCR5 and the CCL5 ligand have been detected in some hematological malignancies, lymphomas, and a great number of solid tumors, but extensive studies on the role of the CCL5/CCR axis were performed only in a limited number of cancers. CCL5 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 35.2 kDa and the accession number is P30882.
TMPK-01483 HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated

AFPD,AFP,Alpha-fetoprotein,HPAFP,MHC,FETA,Alpha-1-fetoprotei...

Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01515 HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)

HPAFP,Alpha-fetoprotein,MHC,FETA,Alpha-feto,Alpha-1-fetoprot...

Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01519 HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)

MHC,FETA,AFP,Alpha-feto,AFPD,Alpha-1-fetoprotein,HPAFP,Alpha...

Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01520 HLA-A*02:01&B2M&AFP (PLFQVPEPV) Tetramer Protein, Human, MHC (His & Avi)

Alpha-1-fetoprotein,AFP,HPAFP,FETA,AFPD,MHC,Alpha-fetoprotei...

Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01417 HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

Alpha-1-fetoprotein,HPAFP,AFPD,AFP,Alpha-feto,MHC,FETA,Alpha...

Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-00009 CCL5 Protein, Human, Recombinant (His & Avi), Biotinylated

RANTES,SIS-δ,D17S136E,TCP228,eoCP,SIS-delta,SCYA5,CCL5,SISd,...

Human E. coli
The CCR5 and the CCL5 ligand have been detected in some hematological malignancies, lymphomas, and a great number of solid tumors, but extensive studies on the role of the CCL5/CCR axis were performed only in a limited number of cancers. CCL5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 10.89 kDa and the accession number is P13501.
TMPK-00592 Latexin Protein, Human, Recombinant (His)

ECI,TCI,LXN,MUM

Human E. coli
Latexin, the endogenous protein inhibitor of the A/B subfamily of metallocarboxypeptidases, is expressed in small nociceptive neurons in sensory ganglia and in a subset of neurons in the telencephalon. Recently, the latexin (Lxn) gene was identified as a potential tumor suppressor in several types of solid tumors and lymphoma, and Lxn expression was found to be absent or downregulated in leukemic cells.
TMPK-00553 ADAM9 Protein, Cynomolgus, Recombinant (His)

Adam9,CORD9,mKIAA0021,Meltrin-γ,Meltrin-gamma,ADAM 9,Mltng,M...

Cynomolgus HEK293 Cells
A disintegrin and metalloproteinase 9 (ADAM9) is a member of the transmembrane ADAM family. It is expressed in different types of solid cancer and promotes tumor invasiveness. ADAM9 may be a prognostic marker for vestibular schwannomas (VS), and ADAM9 inhibition might have the potential as a systemic approach for the treatment of VS.
TMPK-01477 HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated

HPAFP,FETA,Alpha-1-fetoprotein,AFPD,AFP,Alpha-feto,MHC,Alpha...

Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01484 HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)

HPAFP,FETA,AFP,AFPD,Alpha-1-fetoprotein,MHC,Alpha-fetoprotei...

Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPY-03859 DHRS9 Protein, Human, Recombinant (His)

3α-HSD,RDHTBE,3ALPHA-HSD,RDH-E2,RETSDR8,dehydrogenase/reduct...

Human E. coli
Dehydrogenase/reductase (SDR family) member 9 (DHRS9) is aberrantly expressed in colorectal cancer (CRC), the decreased expression of DHRS9 correlates with tumor progression and may serve as a potential prognostic biomarker in CRC. The human regulatory macrophage (Mreg) has emerged as a promising cell type for use as a cell-based adjunct immunosuppressive therapy in solid organ transplant recipients. DHRS9 is a specific and stable marker of human Mregs.
TMPK-01521 HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi)

MHC,Alpha-feto,AFPD,Alpha-1-fetoprotein,Alpha-fetoprotein,FE...

Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01436 HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

Alpha-1-fetoprotein,FETA,MHC,Alpha-feto,AFPD,Alpha-fetoprote...

Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01478 HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi), Biotinylated

AFP,FETA,Alpha-feto,HPAFP,Alpha-1-fetoprotein,MHC,Alpha-feto...

Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01081 Glypican 2/GPC2 Protein, Mouse, Recombinant (His)

Cerebroglycan,2410016G05Rik,GPC2,Glypican-2

Mouse HEK293 Cells
Glypicans can function as coreceptors for multiple signaling molecules known for regulating cell growth, motility, and differentiation. Some members of the glypican family, including glypican 2 (GPC2) and glypican 3 (GPC3), are expressed in childhood cancers and liver cancers, respectively. Antibody-based therapies targeting glypicans are being investigated in preclinical and clinical studies, with the goal of treating solid tumors that do not respond to standard therapies.
TMPK-01482 HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)

MHC,AFPD,Alpha-fetoprotein,FETA,Alpha-1-fetoprotein,AFP,HPAF...

Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
TMPK-01018 B7-H3 Protein, Human, Recombinant (aa 29-245, His)

PRO352,B7H3, UNQ309,PSEC0249,CD276,B7-H3,B7 homolog 3

Human HEK293 Cells
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (aa 29-245, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weig...
TMPK-00315 B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi), Biotinylated

 4Ig-B7-H3,CD276,UNQ309,B7-H3,PRO352,PSEC0249,B7 homolog 3

Human HEK293 Cells
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. T...
TMPK-00445 VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi)

PCL,PCLFLT41,VEGFR3,FLT-4,LMPH1A,FLT-41,VEGFR-3

Human HEK293 Cells
Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosis in several solid tumors.VEGF-R1, -R2 and -R3 were highly expressed in CRC cells and stromal vessels. VEGF-R1 strong positive staining correlated with shorter survival after CRC surgery. VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 87.4 k...
TMPK-00314 B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi)

B7-H3,PSEC0249,PRO352, 4Ig-B7-H3,B7 homolog 3,UNQ309,CD276

Human HEK293 Cells
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted m...
TMPK-01017 B7-H3 Protein, Human, Recombinant (aa 29-245, hFc)

B7H3,B7-H3,B7 homolog 3,PSEC0249,CD276,PRO352, UNQ309

Human HEK293 Cells
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (aa 29-245, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weig...
TMPK-00446 VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated

PCL,FLT-41,LMPH1A,FLT-4,VEGFR3,PCLFLT41,VEGFR-3

Human HEK293 Cells
Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosis in several solid tumors.VEGF-R1, -R2 and -R3 were highly expressed in CRC cells and stromal vessels. VEGF-R1 strong positive staining correlated with shorter survival after CRC surgery. VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted m...
TMPY-04118 Livin/BIRC7 Protein, Human, Recombinant (His)

MLIAP,baculoviral IAP repeat containing 7,RNF50,KIAP,ML-IAP,...

Human E. coli
BIRC7, a new member of inhibitor of the apoptosis protein family, is expressed in fetal tissues and most solid tumors in humans. BIRC7/livin expression is a novel prognostic marker in adult acute leukemia. Livin/BIRC7 is a member of the inhibitors of apoptosis proteins family, which are involved in tumor development through the inhibition of caspases. Livin/BIRC7 is specifically over-expressed in ACC, suggesting that it might be involved in adrenocortical tumorigenesis and represent a new molecu...
TMPY-03876 PTGFRN Protein, Cynomolgus, Recombinant (His)

prostaglandin F2 receptor inhibitor

Cynomolgus HEK293 Cells
EWI-F, also known as PTGFRN, is inversely related to the loss of CD9. Its expression correlates with the metastatic status of hLT. EWI-F inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. EWI-F expression positively correlates with the metastatic status of hLT, and that the upregulation of EWI-F expression could be one of the mechanisms underlying the loss of CD9 in solid tumours.
TMPK-01016 B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled

B7H3, UNQ309,PRO352,PSEC0249,B7 homolog 3,B7-H3,CD276

Human HEK293 Cells
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular w...
TMPJ-01207 UPP1 Protein, Human, Recombinant (His)

UPP1,Uridine Phosphorylase 1,UPP1 Protein

Human E. coli
Uridinephosphorylase 1 (UPP1) is a member of the family of pentosyltransferase. UPP1 catalyses the reversible phosphorolysis of uridine to uracil. The expression levels and the enzymatic activity of UPP1 are higher in human solid tumors than in adjacent normal tissues. The high level of UPP1 expression in some tumors makes it a potential prognosticfactor for some cancers, such as oral squamous cell carcinoma. UPP1 is important for the homeostatic regulation of intracellular and plasma uridine c...
TMPY-03987 T Plastin/PLS3 Protein, Human, Recombinant (His)

BMND18,T-plastin,plastin 3

Human E. coli
PLS3, also known as plastin 3, belongs to the plastin family. Members of this family are actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. There are two ubiquitous plastin isoforms in humans: L and T. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, m...
TMPY-02135 S100A16 Protein, Human, Recombinant

S100F,DT1P1A7,S100 calcium binding protein A16,MGC17528,AAG1...

Human E. coli
S100A16 is a member of S100 protein superfamily that carries calcium-binding EF-hand motifs. S100 proteins are cell- and tissue-specific and are involved in many intra- and extracellular processes through interacting with specific target proteins. S100A16 expression was found to be astrocyte-specific. The S100A16 protein was found to accumulate within nucleoli and to translocate to the cytoplasm in response to Ca(2+) stimulation. The homodimeric structure of human S100A16 in the apo state has be...
TMPY-04936 BCL2A1 Protein, Human, Recombinant (His)

BFL1,ACC1,ACC-2,GRS,ACC-1,HBPA1,BCL2 related protein A1,BCL2...

Human E. coli
B-cell lymphoma 2-related protein A1 (BCL2A1) is a member of the BCL-2 family of anti-apoptotic proteins that confers resistance to treatment with anti-cancer drugs. Immunohistochemical expression of Wnt11 and BCL2A1 in complete moles and normal villi. Bcl2 family proteins control mitochondrial apoptosis and its members exert critical cell type and differentiation stage-specific functions, acting as barriers against autoimmunity or transformation. Anti-apoptotic Bcl2a1/Bfl1/A1 is frequently der...
TMPY-01583 ALDH1A1 Protein, Human, Recombinant (His)

ALDH11,ALDC,PUMB1,ALDH-E1,HEL-S-53e,HEL-9,aldehyde dehydroge...

Human E. coli
Aldehyde dehydrogenase 1 family, member A1 (ALDH1A1), also known as Aldehyde dehydrogenase 1 (ALDH1), or Retinaldehyde Dehydrogenase 1 (RALDH1), is an enzyme that is expressed at high levels in stem cells and that has been suggested to regulate stem cell function. The retinaldehyde dehydrogenase (RALDH) subfamily of ALDHs, composed of ALDH1A1, ALDH1A2, ALDH1A3, and ALDH8A1, regulate development by catalyzing retinoic acid biosynthesis. The ALDH1A1 protein belongs to the aldehyde dehydrogenases f...
TMPY-00920 SFRP2 Protein, Mouse, Recombinant (His)

secreted frizzled-related protein 2,AI851596,Sdf5

Mouse HEK293 Cells
The Secreted frizzled-related protein (SFRP) family consists of five secreted glycoproteins in humans (SFRP1~5) that act as extracellular signaling ligands. Each SFRP is approximately 3 amino acids in length and contains a cysteine-rich domain (CRD) that shares 3-5% sequence homology with the CRD of Frizzled (Fz) receptors, a putative signal sequence, and a conserved hydrophilic carboxy-terminal domain. SFRPs are able to bind Wnt proteins and Fz receptors in the extracellular compartment. The in...

重组蛋白

CCL5 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-00008
Species: Mouse
Expression System: HEK293 Cells
HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01483
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01515
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01519
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&AFP (PLFQVPEPV) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01520
Species: Human
Expression System: HEK293 Cells
HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
Cat.No: TMPK-01417
Species: Human
Expression System: HEK293 Cells
CCL5 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00009
Species: Human
Expression System: E. coli
Latexin Protein, Human, Recombinant (His)
Cat.No: TMPK-00592
Species: Human
Expression System: E. coli
ADAM9 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00553
Species: Cynomolgus
Expression System: HEK293 Cells
HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01477
Species: Human
Expression System: HEK293 Cells
HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01484
Species: Human
Expression System: HEK293 Cells
DHRS9 Protein, Human, Recombinant (His)
Cat.No: TMPY-03859
Species: Human
Expression System: E. coli
HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01521
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
Cat.No: TMPK-01436
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01478
Species: Human
Expression System: HEK293 Cells
Glypican 2/GPC2 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01081
Species: Mouse
Expression System: HEK293 Cells
HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01482
Species: Human
Expression System: HEK293 Cells
B7-H3 Protein, Human, Recombinant (aa 29-245, His)
Cat.No: TMPK-01018
Species: Human
Expression System: HEK293 Cells
B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00315
Species: Human
Expression System: HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00445
Species: Human
Expression System: HEK293 Cells
B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00314
Species: Human
Expression System: HEK293 Cells
B7-H3 Protein, Human, Recombinant (aa 29-245, hFc)
Cat.No: TMPK-01017
Species: Human
Expression System: HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated
Cat.No: TMPK-00446
Species: Human
Expression System: HEK293 Cells
Livin/BIRC7 Protein, Human, Recombinant (His)
Cat.No: TMPY-04118
Species: Human
Expression System: E. coli
PTGFRN Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-03876
Species: Cynomolgus
Expression System: HEK293 Cells
B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled
Cat.No: TMPK-01016
Species: Human
Expression System: HEK293 Cells
UPP1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01207
Species: Human
Expression System: E. coli
T Plastin/PLS3 Protein, Human, Recombinant (His)
Cat.No: TMPY-03987
Species: Human
Expression System: E. coli
S100A16 Protein, Human, Recombinant
Cat.No: TMPY-02135
Species: Human
Expression System: E. coli
BCL2A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04936
Species: Human
Expression System: E. coli
ALDH1A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01583
Species: Human
Expression System: E. coli
SFRP2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00920
Species: Mouse
Expression System: HEK293 Cells
Cat. No. Product Name Target Signaling Pathways
TMIJ-0007 Malachite Green-d5 picrate

Malachite Green-d5 picrate 是 Malachite Green picrate 的氘代化合物。Malachite Green picrate 的 CAS 号为 57704-66-2。Malachite green (Solid Green Crystals O) 是一种 N-甲基化二氨基三苯基甲烷染料,可用于着色。
TMIJ-0347 Phenol-d6

Phenol-d6 是 Phenol 的氘代化合物。Phenol 的 CAS 号为 108-95-2。Phenol 是一种有毒的无色结晶固体,具有类似医院气味的甜焦油气味。它通常用作防腐剂和消毒剂。它对包括一些真菌和病毒在内的多种微生物有活性,但对孢子只有缓慢的效果。它已被用于消毒皮肤和缓解瘙痒。苯酚还用于制备化妆品,包括防晒霜、染发剂和亮肤制剂。它还用于生产药物(它是工业生产阿司匹林的原料)、除草剂和合成树脂。
TMIJ-0416 Phenol-d5 (2,3,4,5,6-d5)

Phenol-d5 (2,3,4,5,6-d5) 是 Phenol 的氘代化合物。Phenol 的 CAS 号为 108-95-2。Phenol 是一种有毒的无色结晶固体,具有类似医院气味的甜焦油气味。它通常用作防腐剂和消毒剂。它对包括一些真菌和病毒在内的多种微生物有活性,但对孢子只有缓慢的效果。它已被用于消毒皮肤和缓解瘙痒。苯酚还用于制备化妆品,包括防晒霜、染发剂和亮肤制剂。它还用于生产药物(它是工业生产阿司匹林的原料)、除草剂和合成树脂。

同位素标记化合物

Malachite Green-d5 picrate
Cat.No: TMIJ-0007
Synonym:
Target:
Phenol-d6
Cat.No: TMIJ-0347
Synonym:
Target:
Phenol-d5 (2,3,4,5,6-d5)
Cat.No: TMIJ-0416
Synonym:
Target:
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