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Targets Recommended: APC

98

抑制剂 & 化合物

9

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T8561 Apcin

APC Cell Cycle/Checkpoint
Apcin 是后期促进复合物/环体 (APC/C(Cdc20)) E3 连接酶活性的有效竞争性抑制剂,可通过与 Cdc20 结合并阻止底物识别竞争性地抑制 APC/C 依赖性泛素化。它占据 WD40 结构域侧面的 D-box 结合口袋,并可以延长有丝分裂。它通过阻断有丝分裂退出并通过共同添加 Ts-Arg-OMe 协同放大而起作用。
T16670 PS210

PDK PI3K/Akt/mTOR signaling
PS210 是针对 PDK1的 PIF 结合口袋的、选择性的、有效的 PDK1激活剂,对其他蛋白激酶无活性。在细胞中,它的前药 PS423 可作为 PDK1的底物选择性抑制剂,抑制 S6K 的磷酸化和活化。
T9627 PHD-1-IN-1

HIF/HIF Prolyl-Hydroxylase Chromatin/Epigenetic; Metabolism
PHD-1-IN-1 是口服有效的缺氧诱导因子脯氨酰羟化酶结构域 1抑制剂,IC50为 0.034 μM。它与活性位 Fe2+具有独特的单齿结合相互作用,并诱导形成一个 “Arg367-out” 口袋。
T2301 SB 202190

FHPI,SB202190

Apoptosis; p38 MAPK; Autophagy Apoptosis; Autophagy; MAPK
SB 202190 (FHPI) 是一种 p38 MAPK 抑制剂,可以抑制 p38α 和 p38β2 (IC50=50/100 nM),具有选择性和细胞渗透性。SB 202190 具有抗肿瘤活性,还可以诱导人胚胎干细胞向心肌细胞分化。
T8719 SC99

Apoptosis; JAK; STAT Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
SC99 是一种口服有效选择性STAT3抑制剂,靶向 JAK2-STAT3 途径,抑制血小板活化和聚集,有抗骨髓瘤和抗血栓活性。它结合在 JAK2 的 ATP 结合袋中,抑制 JAK2 和 STAT3 的磷酸化。
T9079 Apostatin-1

Apt-1

Others Others
Apostatin-1 (Apt-1) 是一种新型 TRADD 抑制剂。 Apostatin-1 可以与 TRADD 的 N 末端 TRAF2 结合域上的口袋结合。
T10533 BI-2852

Ras GPCR/G Protein; MAPK
BI-2852 是具有纳摩尔亲和力的开关 I/II 口袋(SI/II-口袋)的 KRAS 抑制剂,可抑制 KRAS 突变细胞的下游信号传导和抗增殖作用。
T23969 DCAI

Others Others
DCAI 是一种核苷酸交换和核苷酸释放的抑制剂,通过与 Ras-SOS 界面附近的口袋结合而起作用。
T8700 TKIM

Potassium Channel Membrane transporter/Ion channel
TKIM 是一种 TWIK 相关的钾通道 1 (TREK-1) 抑制剂,与 TREK-1 的中间 (IM) 状态的口袋结合。
T15579 INDY

1-(3-ethyl-5-hydroxy-1,3-benzothiazol-2-ylidene)propan-2-one

DYRK Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors
INDY 是 Dyrk1A 和 Dyrk1B 的 ATP 竞争性抑制剂,IC50 分别为 0.24 μM 和 0.23 μM,对 Dyrk1A ATP 口袋的 Ki 为 0.18 μM。
T1980 HA14-1

BCL Apoptosis
HA14-1 是一种 Bcl-2/Bcl-xL 拮抗剂,与 Bcl-2 上的特定口袋结合,IC50约为 9 μM。
T17205 UNC2541

Others; FLT; TAM Receptor Angiogenesis; Others; Tyrosine Kinase/Adaptors
UNC2541 是 Mer 酪氨酸激酶特异性抑制剂,与 MerTK ATP 结合口袋结合的IC50值为 4.4 nM,对其选择性远高于 Axl,Tyro3 和 Flt3。它能够抑制磷酸化的 MerTK (pMerTK;EC50,510 nM)。
T8659 K-Ras-PDEδ-IN-1

PDE Metabolism
K-Ras-PDEδ-IN-1 是新型的 K-Ras-PDEδ 抑制剂,它能够以低纳摩尔Kd8 nM 与 PDEδ 的法尼基结合袋竞争性结合。
T9095 Necrostatin-34

2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4

RIP kinase Apoptosis; NF-κB
Necrostatin-34 (2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4) 是一种 RIPK1 激酶抑制剂,通过在激酶结构域中占据一个独特的结合口袋,将 RIPK1 激酶稳定在非活性构象中。
T3163 PS 48

PDK PI3K/Akt/mTOR signaling
PS 48 已被证明是一种 PKB 激酶 (PDK1) 激活剂 (Kd: 10.3 μM)。该化合物选择性地与 PKB 激酶 (PDK1) 的 PIF 结合口袋结合。
T27133 DCLX069

DCLX 069,DCLX-069

Histone Methyltransferase Chromatin/Epigenetic
DCLX069 是一种选择性蛋白精氨酸甲基转移酶 1 抑制剂,IC50值为 17.9 µM,对 PRMT4 和 PRMT6 的活性较低。它可有效阻断乳腺癌、肝癌和急性髓性白血病细胞系中的细胞增殖。
T14978 CL-82198

MMP Proteases/Proteasome
CL-82198 是 MMP-13选择性抑制剂。它能够与 MMP-13 的整个 S1' 口袋结合,这是其对 MMP-13 选择性和对其他 MMP 缺乏抑制活性的基础。它可用于研究骨关节炎。
T35694 OD36

OD 36,OD 36 hydrochloride,OD-36

ALK; RIP kinase Angiogenesis; Apoptosis; NF-κB; Tyrosine Kinase/Adaptors
OD36 是一种选择性强效 RIPK2 抑制剂,IC50 为 5.3 nM。OD36 可抑制 ALK2 信号传导和成骨分化(KD:37 nM),并能与 ALK2 激酶 ATP 袋有效结合。
T10585 Bozitinib

CBT-101,PLB-1001

c-Met/HGFR Tyrosine Kinase/Adaptors
Bozitinib (PLB-1001) 是一种可透过血脑屏障的、高效的、选择性的的、 ATP 竞争性的小分子 c-MET 激酶抑制剂,能够与酪氨酸激酶超家族的常规 ATP 结合口袋结合。
T67753 Trifluoromethyl-tubercidin

Influenza Virus Microbiology/Virology
Trifluoromethyl-tubercidin (TFMT)可抑制宿主Mtr1并抑制病毒复制。TFMT 通过其S-adenosyl-l-methionine 结合袋相互作用抑制Mtr1,限制流感病毒复制。TFMT 能有效抑制病毒在小鼠体内的复制,毒性很小。
T9103 BVDV-IN-1

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
BVDV-IN-1 是一种牛病毒性腹泻病毒 (BVDV) 的非核苷抑制剂 (NNI),EC50 为 1.8 μM。它直接与 BVDV RdRp 的疏水口袋结合,对耐 NNI 氨基硫脲 (TSC) 的 BVDV 具有抗病毒活性。
T12609 R-10015

LIM Kinase; Reverse Transcriptase Cell Cycle/Checkpoint; Microbiology/Virology
R-10015 是一种高效选择性 LIMK 抑制剂,通过结合 ATP 结合口袋阻断 LIMK,抑制人 LIMK1 的 IC50值为 38 nM。它还发挥广谱抗病毒作用,可用于 HIV 感染研究。
T11807 L002

Others; Histone Acetyltransferase; STAT Chromatin/Epigenetic; JAK/STAT signaling; Others; Stem Cells
L002 是一种细胞可渗透的,可逆特定性乙酰转移酶 p300(KAT3B)抑制剂,IC50为 1.98 μM。 它结合乙酰辅酶 A 口袋并竞争性抑制 FATp300 催化结构域,阻断组蛋白乙酰化和 p53 乙酰化,且抑制 STAT3 激活,有用于高血压引起的心脏肥大和纤维化的研究潜力。
T8931L ICCB-19 hydrochloride

ICCB-19 HCl(750621-52-4 free base)

Apoptosis; Others; Autophagy; RIP kinase Apoptosis; Autophagy; NF-κB; Others
ICCB-19 hydrochloride (ICCB-19 HCl) 是RIPK1激酶活性的间接抑制剂。它是一种 TRADD 抑制剂,可与 TRADD 的 N 端结构域结合,破坏其与 TRADD-C 和 TRAF2 的结合,诱导自噬和长寿命蛋白质的降解。
T29111 VPC-13566

Androgen Receptor Endocrinology/Hormones
VPC-13566 是一种 BF3 特异性小分子,可有效抑制雄激素受体转录活性并从 BF3 口袋中置换出 BAG1L 肽。 VPC-13566 抑制各种前列腺癌细胞系的生长,并减少小鼠中 AR 依赖性前列腺癌异种移植肿瘤的生长。
T8873 Bractoppin

Others; DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
Bractoppin 是一种BRCA1 (t)BRCT domain 识别磷酸肽的选择性抑制剂,IC50为 74 nM。它优先抑制 BRCA1 -tBRCT 依赖的 DNA 损伤。它减少 BRCA1 对 DNA 断裂片段的招募,进而抑制损伤诱导的 G2 期阻滞和重组酶 RAD51 的组装。
T14322 ARP-100

MMP-2 Inhibitor III

MMP Proteases/Proteasome
ARP-100 (MMP-2 Inhibitor III) 是选择性基质金属蛋白酶MMP-2抑制剂 (IC50=12 nM)。它对 MMP-1 (>50 μM),MMP-3 (4.5 μM),MMP-7 (>50 μM) 和MMP-9 (0.2 μM) 的抑制活性较小。它与 MMP-2 的 S1'口袋相互作用,并在体外对基质胶的侵袭模型中显示抗侵袭特性。
T72055 FM04

P-gp Membrane transporter/Ion channel; Neuroscience
FM04 是一种具有口服活性和高效性的 P-糖蛋白 (P-gp) 抑制剂 ,EC50 值为 83 nM。FM04 可以与人P-gp核苷酸结合域2(NBD2)中的Q1193和I1115相互作用。从而破坏 R262-Q1081-Q1118 相互作用口袋并解偶联 ICL2-NBD2 相互作用,从而抑制 P-gp。FM04 可用于癌症和肿瘤的治疗。
T3157 COH29

RNR Inhibitor COH29

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
COH29 (RNR Inhibitor COH29) 是一种口服可用的芳香族取代噻唑,是人类核糖核苷酸还原酶 (RNR) 的抑制剂,具有潜在的抗肿瘤活性。它抑制核糖核苷酸还原酶的IC50为 16 μM。
T24676 PS423

PS210AM,PS 210 AM,PS 423,PS210-AM,PS-423

Others Others
PS423 is a substrate-selective protein kinase PDK1 inhibitor that acts by binding to the PIF-pocket allosteric docking site.
T39440 CXCL12 ligand 1

Others Others
CXCL12 ligand 1 is the first ligand of the sY12-binding pocket on chemokine CXCL12 .
T23656 VUF11211

VUF-11211,VUF 11211

Others Others
VUF11211 is an effective antagonist of CXCR3 that acts by extending from the minor pocket into the major pocket of the transmembrane domains.
T71939 PS77

Others Others
PS77 is a Pkh inhibitor directed to the PIF-pocket with increased selectivity for C. albicans Pkh2.
T24099 GP29

GP-29,GP 29

Others Others
GP29 is a Type II kinase inhibitor of the IRE1α endoribonuclease that acts by targeting the ATP-binding pocket of IRE1α.
T10446 BA-53038B

Others Others
BA-53038B is an HBV core protein allosteric modulator (CpAM), binding to the HAP pocket and modulating HBV capsid assembly in a distinct manner (EC50: 3.32 μM).
T23901 CM026

CM 026,CM-026

Others Others
CM026 is a selective aldehyde dehydrogenase 1A1 inhibitor that acts by binding within the aldehyde binding pocket of ALDH1A1 in an uncompetitive partial mode of inhibition.
T24740 RS-104966

Others Others
RS-104966 is an inhibitor of collagenase that acts by inducing the conformational change in the side-chains of the S1 pocket of MMP-1.
T24543 NP603

NP 603,NP-603

Others Others
NP603 is a cell-permeable inhibitor of FGFR1, PDGFRβ, and VEGFR2 that binds to the ATP pocket. It also is a very weak EGFR inhibitor.
T68466 BI-207524

Others Others
BI-207524 is a novel NS5B Thumb Pocket 1 Inhibitor with Improved Potency for the Potential Treatment of Chronic Hepatitis C Virus Infection.
T24806 SMBA2

SMBA-2,NSC4436,NSC 4436,NSC-4436,SMBA 2

Others Others
SMBA2 is a Bax activator. It acts by specifically targeting the binding pocket at S184.
T41113 3BrB-PP1

3BrB-PP1

Others Others
3BrB-PP1 is an ATP-competitive analog that exhibits specific inhibitory activity towards protein kinase. It is effective in inhibiting protein kinase with mutations in the ATP-binding pocket, specifically the mutation of Thr97 within Sty1's ATP-binding pocket.
T39955 JNJ-67569762

Others Others
JNJ-67569762 is a selective BACE1 inhibitor targeting the S3 pocket ( IC 50 = 2.7 nM).
T30089 AP-22161

AP22161,G7VE62573J,UNII-G7VE62573J,SCHEMBL7243003,AP 22161

Others Others
AP-22161 selectively binds the Src SH2 domain by targeting highly conserved phosphotyrosine binding to cysteine residues in the pocket. AP-22161 selectively inhibits Src SH2 binding and can be used to inhibit osteoclast absorption.
T28389 PF-6422899

PF6422899,PF 6422899

Others Others
PF-6422899 irreversibly inhibits EGFR kinase activity by binding covalently to active-site cysteine residues in the ATP binding pocket of EGFR.
T24098 GP17

GP-17,GP 17

Others Others
GP17 is a type II kinase inhibitor of the IRE1α endoribonuclease that acts by targeting the ATP-binding pocket of IRE1α.
T16119 MLT-747

Others Others
MLT-747 is an effective and allosteric inhibitor of MALT1. It binds MALT1 in the allosteric Trp580 pocket (IC50: 14 nM).
T26343 YK5

YK 5,YK-5

Others Others
YK5 is an allosteric inhibitor pocket of Hsp70 and represents a previously unknown chemical tool to investigate cellular mechanisms associated with Hsp70.
T10374 ARS-1323-alkyne

Ras GPCR/G Protein; MAPK
ARS-1323-alkyne 是switch-II pocket (S-IIP)抑制剂,能够特异性报告活体细胞中 KRASG12C 核苷酸的状态。
T32500 L6Y

TTR stabilizer L6

Others Others
L6Y is a transthyretin (TTR) stabilizer which binds to the T4 binding pocket of TTR and prevents the dissociation of TTR to monomer.
T71843 HPA-12

Others Others
HPA-12 is a novel potent inhibitor of cert, binding to the ceramide-binding pocket in the cert start domain

化合物

Apcin
Cat.No: T8561
Synonym:
Target: APC
PS210
Cat.No: T16670
Synonym:
Target: PDK
PHD-1-IN-1
Cat.No: T9627
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase
SB 202190
Cat.No: T2301
Synonym: FHPI,SB202190
Target: Apoptosis, p38 MAPK, Autophagy
SC99
Cat.No: T8719
Synonym:
Target: Apoptosis, JAK, STAT
Apostatin-1
Cat.No: T9079
Synonym: Apt-1
Target: Others
BI-2852
Cat.No: T10533
Synonym:
Target: Ras
DCAI
Cat.No: T23969
Synonym:
Target: Others
TKIM
Cat.No: T8700
Synonym:
Target: Potassium Channel
INDY
Cat.No: T15579
Synonym: 1-(3-ethyl-5-hydroxy-1,3-benzothiazol-2-ylidene)propan-2-one
Target: DYRK
HA14-1
Cat.No: T1980
Synonym:
Target: BCL
UNC2541
Cat.No: T17205
Synonym:
Target: Others, FLT, TAM Receptor
K-Ras-PDEδ-IN-1
Cat.No: T8659
Synonym:
Target: PDE
Necrostatin-34
Cat.No: T9095
Synonym: 2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4
Target: RIP kinase
PS 48
Cat.No: T3163
Synonym:
Target: PDK
DCLX069
Cat.No: T27133
Synonym: DCLX 069,DCLX-069
Target: Histone Methyltransferase
CL-82198
Cat.No: T14978
Synonym:
Target: MMP
OD36
Cat.No: T35694
Synonym: OD 36,OD 36 hydrochloride,OD-36
Target: ALK, RIP kinase
Bozitinib
Cat.No: T10585
Synonym: CBT-101,PLB-1001
Target: c-Met/HGFR
Trifluoromethyl-tubercidin
Cat.No: T67753
Synonym:
Target: Influenza Virus
BVDV-IN-1
Cat.No: T9103
Synonym:
Target: DNA/RNA Synthesis
R-10015
Cat.No: T12609
Synonym:
Target: LIM Kinase, Reverse Transcriptase
L002
Cat.No: T11807
Synonym:
Target: Others, Histone Acetyltransferase, STAT
ICCB-19 hydrochloride
Cat.No: T8931L
Synonym: ICCB-19 HCl(750621-52-4 free base)
Target: Apoptosis, Others, Autophagy, RIP kinase
VPC-13566
Cat.No: T29111
Synonym:
Target: Androgen Receptor
Bractoppin
Cat.No: T8873
Synonym:
Target: Others, DNA/RNA Synthesis
ARP-100
Cat.No: T14322
Synonym: MMP-2 Inhibitor III
Target: MMP
FM04
Cat.No: T72055
Synonym:
Target: P-gp
COH29
Cat.No: T3157
Synonym: RNR Inhibitor COH29
Target: DNA/RNA Synthesis
PS423
Cat.No: T24676
Synonym: PS210AM,PS 210 AM,PS 423,PS210-AM,PS-423
Target: Others
CXCL12 ligand 1
Cat.No: T39440
Synonym:
Target: Others
VUF11211
Cat.No: T23656
Synonym: VUF-11211,VUF 11211
Target: Others
PS77
Cat.No: T71939
Synonym:
Target: Others
GP29
Cat.No: T24099
Synonym: GP-29,GP 29
Target: Others
BA-53038B
Cat.No: T10446
Synonym:
Target: Others
CM026
Cat.No: T23901
Synonym: CM 026,CM-026
Target: Others
RS-104966
Cat.No: T24740
Synonym:
Target: Others
NP603
Cat.No: T24543
Synonym: NP 603,NP-603
Target: Others
BI-207524
Cat.No: T68466
Synonym:
Target: Others
SMBA2
Cat.No: T24806
Synonym: SMBA-2,NSC4436,NSC 4436,NSC-4436,SMBA 2
Target: Others
3BrB-PP1
Cat.No: T41113
Synonym: 3BrB-PP1
Target: Others
JNJ-67569762
Cat.No: T39955
Synonym:
Target: Others
AP-22161
Cat.No: T30089
Synonym: AP22161,G7VE62573J,UNII-G7VE62573J,SCHEMBL7243003,AP 22161
Target: Others
PF-6422899
Cat.No: T28389
Synonym: PF6422899,PF 6422899
Target: Others
GP17
Cat.No: T24098
Synonym: GP-17,GP 17
Target: Others
MLT-747
Cat.No: T16119
Synonym:
Target: Others
YK5
Cat.No: T26343
Synonym: YK 5,YK-5
Target: Others
ARS-1323-alkyne
Cat.No: T10374
Synonym:
Target: Ras
L6Y
Cat.No: T32500
Synonym: TTR stabilizer L6
Target: Others
HPA-12
Cat.No: T71843
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPY-02028 RON/CD136 Protein, Human, Recombinant (His)

CD136,macrophage stimulating 1 receptor,CDw136,PTK8,RON

Human HEK293 Cells
The tyrosine kinase receptor, macrophage-stimulating 1 receptor (MST1R), a c-met-related tyrosine kinase, also known as the Ron receptor or CD136, controls cell survival and motility programs related to invasive growth. As the tyrosine kinase receptor is comprised of an extracellular domain, MST1R protein contains the ligand-binding pocket and an intracellular region where the kinase domain is located. MST1R signaling may be involved in the regulation of macrophage and T-lymphocyte activation in...
TMPK-00982 NTS1 Protein, Cynomolgus, Recombinant (His)

NTR1,NT,NTRR,NTRH,NTS1,NTSR1,NT/N,NTS,NMN-125,NN,NTR

Cynomolgus HEK293 Cells
Crystal structures of neurotensin receptor subtype 1 (NTS1) allowed us to visualize the binding mode of the endogenous peptide hormone neurotensin and its pharmacologically active C-terminal fragment NT(8-13) within the orthosteric binding pocket of NTS1. NTS1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 18.84 kDa and the accession number is Q2PG57.
TMPH-03158 PAD Protein, Porphyromonas gingivalis, Recombinant (His)

Peptidylarginine deiminase

Porphyromonas gingivalis E. coli
Deiminates the guanidino group of C-terminal arginine residues on a variety of peptides, including the vasoregulatory peptide-hormone bradykinin, to yield ammonia and a citrulline residue. May promote the growth of the pathogen in the periodontal pocket by producing ammonia, ammonia having a protective effect during acidic cleaning cycles in the mouth. PAD Protein, Porphyromonas gingivalis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weig...
TMPK-01162 NTS1 Protein, Mouse, Recombinant (hFc)

NTS1,NTRH,NN,NT,NTR1,NMN-125,NT/N,NTSR1,NTR,NTRR

Mouse HEK293 Cells
Crystal structures of neurotensin receptor subtype 1 (NTS1) allowed us to visualize the binding mode of the endogenous peptide hormone neurotensin and its pharmacologically active C-terminal fragment NT(8-13) within the orthosteric binding pocket of NTS1. NTS1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 42.9 kDa and the accession number is Q9D3P9.
TMPK-00545 HPX Protein, Cynomolgus, Recombinant (His)

Hemopexin,Hpx,Hpxn

Cynomolgus HEK293 Cells
Hemopexin (HPX) serves as scavenger and transporter of toxic plasma heme to the liver. HPX is formed by two four-bladed beta-propeller domains, resembling two thick disks that lock together at a 90 degrees angle. The heme is bound between the two beta-propeller domains in a pocket formed by the interdomain linker peptide.HPX, acting not only as a heme carrier but also displaying transient heme-based ligand binding and (pseudo-)enzymatic properties, could be considered a 'chronosteric' heme-prote...
TMPY-02390 SSPA Protein, E. coli, Recombinant (His)

ssp,pog

E. coli E. coli
Stringent starvation protein A (ssPA), a member of the GST superfamily, is an RNA polymerase-associated transcriptional activator for the lytic development of phage P1 and is essential for stationary phase-induced acid tolerance of E. coli. It indicates that the flexible regions are not critical for SspA function, whereas the surface pocket is important for both transcriptional activation of the phage P1 late promoter and acid resistance of E. coli. SspA is known to be implicated in survival dur...
TMPY-05438 CAN F 4 Protein, Canine, Recombinant (His)

Canine HEK293 Cells
Dog dander is an important cause of respiratory allergy but its content of allergenic components is still incompletely known. The size and the amino acid composition of the ligand-binding pocket indicate that Can f 4 is capable of binding only relatively small hydrophobic molecules which are different from those that Can f 2 is able to bind. The crystal structure of Can f 4 contained both monomeric and dimeric forms of the allergen, suggesting that Can f 4 is able to form transient (weak) dimers...
TMPY-02461 AKR1A1 Protein, Human, Recombinant (His)

DD3,ALDR1,HEL-S-6,aldo-keto reductase family 1, member A1 (a...

Human E. coli
Aldehyde reductase (AKR1A1) is a member of the aldo-keto reductase superfamily, which consists of more than 40 known enzymes and proteins that includes variety of monomeric NADPH-dependent oxidoreductases, such as aldehyde reductase. Aldehyde reductase has wide substrate specificities for carbonyl compounds. These enzymes are implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Aldehyde reductase possess a structure with a beta-alpha-beta fo...
TMPY-01679 LCN1 Protein, Human, Recombinant (His)

TLC,MGC71975,TP,VEGP,Lipocalin 1,PMFA

Human HEK293 Cells
Lipocalin-1, also known as Von Ebner gland protein, VEG protein, Tear Prealbumin, VEGP, Tear lipocalin, and LCN1 is a secreted protein that belongs to the calycin superfamily and Lipocalin family. Human Lipocalin-1 / VEGP was originally described as a major protein of human tear fluid, which was thought to be tear specific. Lipocalin-1 / VEGP is identical to lingual von Ebner's gland protein and is also produced in the prostate, nasal mucosa, and tracheal mucosa. Homologous proteins have been fo...

重组蛋白

RON/CD136 Protein, Human, Recombinant (His)
Cat.No: TMPY-02028
Species: Human
Expression System: HEK293 Cells
NTS1 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00982
Species: Cynomolgus
Expression System: HEK293 Cells
PAD Protein, Porphyromonas gingivalis, Recombinant (His)
Cat.No: TMPH-03158
Species: Porphyromonas gingivalis
Expression System: E. coli
NTS1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-01162
Species: Mouse
Expression System: HEK293 Cells
HPX Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00545
Species: Cynomolgus
Expression System: HEK293 Cells
SSPA Protein, E. coli, Recombinant (His)
Cat.No: TMPY-02390
Species: E. coli
Expression System: E. coli
CAN F 4 Protein, Canine, Recombinant (His)
Cat.No: TMPY-05438
Species: Canine
Expression System: HEK293 Cells
AKR1A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02461
Species: Human
Expression System: E. coli
LCN1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01679
Species: Human
Expression System: HEK293 Cells
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