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Search Results for " metastasis "

Targets Recommended: LPA Receptor LPL Receptor

154

抑制剂 & 化合物

27

天然产物

7

化合物库

110

重组蛋白

3

同位素标记化合物

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Cat. No.	Product Name
L2151	化疗药物库		48 compounds
	48 个肿瘤化疗药物，可以用于高通量和高内涵筛选；
L2200	酪氨酸激酶分子库		1016 compounds
	1016 种酪氨酸激酶抑制剂的独特集合，可用于高通量筛选和高内涵筛选；
L4800	血管生成库		1353 compounds
	1353 个高潜力的抑制或促进血管生成的小分子集合，可用于药物靶点开发、血管生成机理研究的高通量筛选，高内涵筛选；
L2100	抗癌化合物库		7234 compounds
	7234 种肿瘤相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L9420	外泌体相关化合物库		76 compounds
	76 种外泌体相关的化合物，可以用于高通量和高内涵筛选；
L7600	趋化因子抑制剂库		59 compounds
	59 种趋化因子或其受体抑制剂的独特集合，可用于高通量筛选和高内涵筛选；
L8500	HIF-1化合物库		1336 compounds
	1336 个HIF-1相关小分子的独特集合，可用于缺血性疾病、癌症等相关领域的药物开发和药理研究；

化合物库

化疗药物库

Cat.No: L2151

Compounds: 48

酪氨酸激酶分子库

Cat.No: L2200

Compounds: 1016

血管生成库

Cat.No: L4800

Compounds: 1353

抗癌化合物库

Cat.No: L2100

Compounds: 7234

外泌体相关化合物库

Cat.No: L9420

Compounds: 76

趋化因子抑制剂库

Cat.No: L7600

Compounds: 59

HIF-1化合物库

Cat.No: L8500

Compounds: 1336

Cat. No.	Product Name	Target	Signaling Pathways
T6347	Ki16198	LPA Receptor; LPL Receptor	GPCR/G Protein
	Ki16198 是一种可口服的 LPA 受体拮抗剂，是 Ki16425 的甲酯衍生物。它抑制 LPA1 和 LPA3 诱导的肌醇磷酸的Ki值分别为 0.34 和 0.93 μM，可用于胰腺癌发生和转移的研究。
T22336	Galloflavin	Dehydrogenase	Metabolism
	Galloflavin 是乳酸脱氢酶抑制剂。用 Pyruvate 法得到的 Ki 为 5.46 µM (LDH-A) 以及15.06 µM (LDH-B)。它能够阻断 ATP 的生成和糖酵解，从而抑制癌细胞的增殖。
T12580	PTUPB	COX; Epoxide Hydrolase	Immunology/Inflammation; Metabolism; Neuroscience
	PTUPB 是强效的sEH(IC50:0.9 μM)和COX-2(IC50:1.26 μM)的双向抑制剂。
T4033	MSX-130 MSX 130	CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation
	MSX-130 是一种CXCR4拮抗剂，可抑制肿瘤转移。
T9107	NP-G2-044	Others	Others
	NP-G2-044 是fascin 蛋白抑制剂，具有口服活性，IC50值约为 2 μM。它可阻断肿瘤转移并增强抗肿瘤免疫应答。
T9963	MPT0B390	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	MPT0B390 是 HDAC 抑制剂和 TIMP3 诱导剂，可抑制肿瘤生长、转移和血管生成。
T4032	MSX-127 MSX 127	CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation
	MSX-127 是一种CXCR4拮抗剂，可抑制肿瘤转移。
T4306	CCG-203971 CCG203971	Rho; Ras	Cell Cycle/Checkpoint; GPCR/G Protein; MAPK
	CCG-203971 是一种Rho/MRTF/SRF 通路抑制剂，具有潜在的抗转移作用。它有效靶向 RhoA/C 激活的 SRE 荧光素酶，IC50为 6.4 μM。它抑制 PC-3 细胞迁移，IC50为 4.2 μM。
T8310	MMP-9-IN-1	MMP	Proteases/Proteasome
	MMP-9-IN-1 是特异性的基质金属蛋白酶-9 抑制剂，选择性靶向 MMP-9 的血红素域，对其他 MMP 无影响。
T5465	PF-5274857 PF-5274857 freebase	Smo	Stem Cells
	PF-5274857 (PF-5274857 free base) freebase 是有效的、具有口服活性的、选择性的、可透过血脑屏障的 Smo 拮抗剂，其 IC50=5.8 nM，Ki=4.6 nM。它有用于包括激活的 Hh 途径驱动的脑肿瘤和脑转移在内的多种肿瘤的研究潜力。
T10425	AZ084	CCR	Immunology/Inflammation; Microbiology/Virology
	AZ084 是可口服的选择性 CCR8变构拮抗剂，其Ki 值为 0.9 nM，可研究哮喘。
T10297L	AMG 487	CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation
	AMG 487 是可口服的选择性趋化因子受体3拮抗剂，对 I-IP-10、I-ITAC 和 MIG 的 IC50 值分别为 8、15 和 36nM。
T2014	CCG-1423 CCG1423	LRRK2; Rho; Ras	Autophagy; Cell Cycle/Checkpoint; GPCR/G Protein; MAPK
	CCG-1423 是一种选择性 RhoA 通路抑制剂，可抑制 SRF 介导的转录，能抑制细胞的转移前列腺癌PC-3细胞侵袭模型。
T1921	Alpelisib BYL-719	PI3K	PI3K/Akt/mTOR signaling
	Alpelisib (BYL-719) 是一种 PI3Kα 抑制剂 (IC50=5 nM)，具有选择性、有效性和口服活性。Alpelisib 以较低活性抑制 PI3Kβ/γ/δ (IC50=250/290/1200 nM)。Alpelisib 具有抗肿瘤活性，对 PIK3CA 突变肿瘤具有靶向性。
T36758	CAIX Inhibitor S4 S4	Carbonic Anhydrase	Metabolism
	CAIX Inhibitor S4 (S4) 是一种有效的碳酸酐酶 IX/XII 抑制剂，Ki 分别为 7 nM 和 2 nM。 CA II 和 CA I 的 Ki 分别为 546 和 5600 nM。
T27730	KGP94 KGP-94,KGP 94	Cysteine Protease	Proteases/Proteasome
	KGP94 是一种有效的、选择性的和竞争性的溶酶体内肽酶抑制剂。
T0939	Phenytoin 苯妥英,Diphenylhydantoin,5,5-Diphenylhydantoin	Virus Protease; Sodium Channel	Membrane transporter/Ion channel; Microbiology/Virology
	Phenytoin (5,5-Diphenylhydantoin) 是一种有效的电压门控钠离子通道阻滞剂，可减少小鼠乳腺肿瘤的生长和转移，具有抗癫痫活性。
T9236	WSB1 Degrader 1	Others; E1/E2/E3 Enzyme	Others; Ubiquitination
	WSB1 Degrader 1 是具有口服活性的 WSB1降解剂，具有抗癌活性。
T7764	CCG-222740	ROCK; Rho; Ras	Cell Cycle/Checkpoint; Cytoskeletal Signaling; GPCR/G Protein; MAPK; Stem Cells
	CCG-222740 是一种口服有效的选择性Rho/MRTF 途径抑制剂。它也是 α-平滑肌的肌动蛋白表达抑制剂，可减少皮肤纤维化并阻止黑色素瘤转移。
T41003	KG5	Raf; FLT; PDGFR; c-Kit	Angiogenesis; MAPK; Tyrosine Kinase/Adaptors
	KG5 是 PDGFRβ 和 B-Raf 的双重变构抑制剂，对 PDGFRβ 和 PDGFRα 的 Kd 分别为 520 nM 和 300 nM。 KG5 抑制 FLT3、KIT 和 c-Raf，具有抗癌和抗血管生成活性。
T5007	Benproperine phosphate 磷酸苯丙哌林,Blascorid,Pirexyl phosphate	Others; Microtubule Associated	Cytoskeletal Signaling; Others
	Benproperine phosphate (Pirexyl phosphate) 是一种具有口服活性的，肌动蛋白相关蛋白 2/3 复合亚基 2 (ARPC2) 抑制剂。它通过削弱 Arp2/3 功能来减弱肌动蛋白的聚合反应速率。它可抑制癌细胞迁移和肿瘤转移，有用于治疗止咳的潜力。
T0008	Phenytoin sodium 5,5-Diphenylhydantoin sodium salt,Diphantoine,苯妥英钠,Dilantin sodium,Diphenylhydantoin Sodium	Virus Protease; Sodium Channel	Membrane transporter/Ion channel; Microbiology/Virology
	Phenytoin sodium (Diphantoine) 是一种有效的电压门控钠离子通道阻滞剂，可减少小鼠乳腺肿瘤的生长和转移，具有抗癫痫活性。
T25492	Hepln-13 Hepln 13,Hepln13	c-Met/HGFR	Tyrosine Kinase/Adaptors
	Hepln-13 是具有口服活性的Hepsin 抑制剂(IC50:0.33 µM)。它可用于研究转移性前列腺癌。
T24642	YH-306 YH306,TRV055 acetate (25849-90-5 Free base)	MMP; MMP; FAK; Rho; PI3K; Src	Angiogenesis; Cell Cycle/Checkpoint; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Tyrosine Kinase/Adaptors
	YH-306 (TRV055 acetate ) 是 FAK 信号通路的调节剂。 YH-306 显示出抗肿瘤活性，抑制结直肠肿瘤的生长和转移。
T62620	ZY-444	Others	Others
	ZY-444具有潜在的抗癌活性，抑制 PCa 细胞的增殖和转移，抑制皮下肿瘤的生长。
TQ0290	ONO-AE3-208 AE 3-208	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	ONO-AE3-208 (AE 3-208) 是一种 EP4 拮抗剂，可抑制前列腺癌的细胞迁移、侵袭和转移。
T14510	BAY-850	Epigenetic Reader Domain	Chromatin/Epigenetic
	BAY-850 是一种具有选择性和有效的三磷酸腺苷酶家族蛋白 2 (ATAD2) 抑制剂，（IC50 ： 166 nM），在体外和体内模型中抑制卵巢癌的生长和转移。
T12493	PK68	Others; RIP kinase	Apoptosis; NF-κB; Others
	PK68 是 II 型受体相互作用激酶 1 (RIPK1, IC50 = 90 nM) 的有效特异性抑制剂。 PK68可用于治疗炎症性疾病和癌症转移的研究。
T28212	NSC668394 NSC-668394,NSC 668394	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	NSC668394 是一种有效的小分子 ezrin (Thr567) 磷酸化抑制剂。NSC668394 具有潜在的抗肿瘤活性，抑制 ezrin T567 磷酸化，增加 Ca2+依赖性ezrin裂解。NSC668394 可用于研究肿瘤转移。
T27613	inS3-54-A26	STAT	JAK/STAT signaling; Stem Cells
	inS3-54-A26 是 STAT3 的 DNA 结合域的抑制剂。 inS3-54-A26 抑制肿瘤生长、转移和 STAT3 的基因表达。
T20626	Esomeprazole	Proton pump; Cysteine Protease	Membrane transporter/Ion channel; Proteases/Proteasome
	Esomeprazole 是奥美拉唑(omeprazole) 的S-异构体，抑制溶酶体半胱氨酸蛋白酶legumain，防止癌症转移。它是一种质子泵抑制剂（PPI）。
T11947	MARK4 inhibitor 1	Apoptosis; Others; AMPK	Apoptosis; Chromatin/Epigenetic; Others; PI3K/Akt/mTOR signaling
	MARK4 inhibitor 1 是一种MARK4的抑制剂，IC50值为1.54 μM。它抑制癌细胞增殖、转移，诱导凋亡。
T6011	Batimastat 巴马司他,BB94	MMP	Proteases/Proteasome
	Batimastat (BB94) 是广谱MMP 抑制剂，能够抑制MMP-1 (IC50:3 nM)，MMP-2 (IC50:4 nM)，MMP-9 (IC50:4 nM)，MMP-7 (IC50:6 nM) 和 MMP-3 (IC50:20 nM)。
T41094	Wnt/β-catenin agonist 2	GSK-3; Wnt/beta-catenin	Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Stem Cells
	Wnt/β-catenin agonist 2激活 Wnt/β-catenin 信号传导，是一种有效的 Wnt 激动剂。 Wnt/β-catenin agonist 2可用于与信号转导相关的疾病研究，与癌症侵袭转移密切相关。
T9732	VY-3-135	Fatty Acid Synthase	Metabolism
	VY-3-135 是口服有效的乙酰辅酶 A 合成酶 2 (ACSS2)选择性抑制剂，IC50为 44 nM，对重组人 ACSS1 或 ACSS3 没有抑制活性。它有效抑制 ACSS2 依赖性脂肪酸代谢，但对肿瘤中的基因表达没有影响。
T9205	NCGC00378430	Phosphatase; Others	Metabolism; Others
	NCGC00378430 是一种 SIX1/EYA2 相互作用抑制剂。它部分逆转 SIX1 过表达介导的转录和代谢谱，并逆转 SIX1 诱导的 TGF-β 信号传导和上皮-间质转化。在小鼠模型中，它能够抑制 SIX1 介导的乳腺癌转移。
T15574	Incyclinide COL-3,CMT-3	MMP	Proteases/Proteasome
	Incyclinide (COL-3) 是一种基质金属蛋白酶 (MMP) 抑制剂，能够诱导细胞外基质降解，抑制血管生成，肿瘤生长和侵袭以及转移。
T12731	RIPK1-IN-7	RIP kinase	Apoptosis; NF-κB
	RIPK1-IN-7 是一种选择性有效的 RIPK1 抑制剂，Kd 值为 4 nM，IC50值为 11 nM。在实验性 B16 黑色素瘤肺转移模型中表现出优异的抗转移活性。
T3710	XMD16-5	Tyrosinase; PPAR	DNA Damage/DNA Repair; Metabolism; Proteases/Proteasome
	XMD16-5 是TNK2抑制剂，对D163E 和R806Q 突变体的IC50值分别为16和77nM。
T10426	AZ12601011	ALK	Angiogenesis; Tyrosine Kinase/Adaptors
	AZ12601011 is a highly potent and selective inhibitor of the TGFBR1 kinase, administered orally. It displays an IC50 of 18 nM and a Kd of 2.9 nM. By selectively targeting ALK4, TGFBR1, and ALK7, AZ12601011 effectively inhibits the phosphorylation of SMAD2. Additionally, it has been shown to hinder the growth and metastasis of mammary tumors [1].
T26629	Angstrom6 A-6,A 6 peptide,A6,A 6,A6 peptide,A-6 peptide	PAI-1	Metabolism
	Angstrom6 (A-6 peptide) 是一种从单链尿激酶纤溶酶原激活剂(scuPA)中提取的 8 肽，它能干扰 uPA/uPAR 级联反应并抑制下游效应。Angstrom6 具有抗肿瘤活性，能通过与 CD44 结合并调节 CD44 介导的细胞信号传导，抑制肿瘤细胞的迁移、侵袭和转移。
T14496	BAMB-4 ITPKA-IN-C14	Others	Others
	BAMB-4 (ITPKA-IN-C14) 是一种新型的膜渗透型ITPKA 抑制剂，在ADP-Glo 实验中的IC50值为37uM。
TP1472	Tyroserleutide	Others	Others
	Tyroserleutide 是一种可从猪脾脏的降解产物中分离得到的小分子三肽，在体内外均对肿瘤生长具有抑制作用。
T15367	Gadoxetate Disodium Gd-EOB-DTPA Disodium,钆塞酸二钠,ZK 139834	Others	Others
	Gadoxetate Disodium 是一种肝胆系统中磁共振成像 (MRI) 中的造影剂，能够在正常的功能性肝细胞中累积，可用于局灶性肝脏病变（如肝细胞癌或 T1 加权成像的肝转移）的研究。
T16549	PKI-166	VEGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	PKI-166是一种可口服的EGF-R 酪氨酸激酶抑制剂（IC50 ： 0.7 nM），具有有效性和选择性。PKI-166能有效抑制包括胰腺癌在内的多种人类癌细胞的生长和转移。
T84314	BFC1108	Apoptosis	Apoptosis
	BFC1108 可靶向 Bcl-2 并将其转化为促凋亡蛋白，抑制Bcl-2高表达的三阴性乳腺癌异种移植物的生长，抑制乳腺癌肺转移，促使表达 Bcl-2 的癌症细胞凋亡。
T29231	ZLD1039 ZLD-1039,ZLD 1039	Histone Methyltransferase	Chromatin/Epigenetic
	ZLD1039 是一种口服有效的、高选择性 EZH2 抑制剂。ZLD1039 高效抑制 EZH2 野生型及 Y641F 和 A677G 突变型，IC50 分别为 5.6、15 和 4.0 nM。ZLD1039 抑制乳腺肿瘤的生长和转移。
T10904	CWP232228	Wnt/beta-catenin	Cytoskeletal Signaling; Stem Cells
	CWP232228 是一种高效的、选择性的Wnt/β-catenin 信号通路抑制剂，在细胞核中，拮抗 β-catenin 与 T 细胞因子结合。它能够抑制乳腺癌和肝癌干细胞的生长，抑制肿瘤的形成和转移，且没有毒性。
T27371	FR-167356 FR167356,FR 167356	ATPase	Membrane transporter/Ion channel
	FR-167356 是 a3 异构体液泡型 H+-ATPase 的特异性抑制剂，对破骨细胞质膜、肾刷状缘膜和巨噬细胞微粒体的 IC50 分别为 170 nM、370 nM 和 220 nM。 FR-167356 减少 B16-F10 细胞的骨转移。
T12006	Metarrestin ML246	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Metarrestin (ML246) 是一种口服有效的选择性核仁周区室 (PNC) 抑制剂，可有效抑制转移。Metarrestin 破坏核仁结构并抑制 RNA 聚合酶 (Pol) I 转录，部分是通过与翻译延伸因子 eEF1A2 的相互作用。

化合物

Cat.No: T6347

Target: LPA Receptor, LPL Receptor

Cat.No: T22336

Target: Dehydrogenase

Cat.No: T12580

Target: COX, Epoxide Hydrolase

Cat.No: T4033

Synonym: MSX 130

Target: CXCR

Cat.No: T9107

Target: Others

Cat.No: T9963

Target: HDAC

Cat.No: T4032

Synonym: MSX 127

Target: CXCR

Cat.No: T4306

Synonym: CCG203971

Target: Rho, Ras

Cat.No: T8310

Target: MMP

Cat.No: T5465

Synonym: PF-5274857 freebase

Target: Smo

Cat.No: T10425

Target: CCR

Cat.No: T10297L

Target: CXCR

Cat.No: T2014

Synonym: CCG1423

Target: LRRK2, Rho, Ras

Cat.No: T1921

Synonym: BYL-719

Target: PI3K

CAIX Inhibitor S4

Cat.No: T36758

Synonym: S4

Target: Carbonic Anhydrase

Cat.No: T27730

Synonym: KGP-94,KGP 94

Target: Cysteine Protease

Cat.No: T0939

Synonym: 苯妥英,Diphenylhydantoin,5,5-Diphenylhydantoin

Target: Virus Protease, Sodium Channel

WSB1 Degrader 1

Cat.No: T9236

Target: Others, E1/E2/E3 Enzyme

Cat.No: T7764

Target: ROCK, Rho, Ras

Cat.No: T41003

Target: Raf, FLT, PDGFR, c-Kit

Benproperine phosphate

Cat.No: T5007

Synonym: 磷酸苯丙哌林,Blascorid,Pirexyl phosphate

Target: Others, Microtubule Associated

Phenytoin sodium

Cat.No: T0008

Synonym: 5,5-Diphenylhydantoin sodium salt,Diphantoine,苯妥英钠,Dilantin sodium,Diphenylhydantoin Sodium

Target: Virus Protease, Sodium Channel

Cat.No: T25492

Synonym: Hepln 13,Hepln13

Target: c-Met/HGFR

Cat.No: T24642

Synonym: YH306,TRV055 acetate (25849-90-5 Free base)

Target: MMP, MMP, FAK, Rho, PI3K, Src

Cat.No: T62620

Target: Others

Cat.No: TQ0290

Synonym: AE 3-208

Target: Prostaglandin Receptor

Cat.No: T14510

Target: Epigenetic Reader Domain

Cat.No: T12493

Target: Others, RIP kinase

Cat.No: T28212

Synonym: NSC-668394,NSC 668394

Target: PKC

Cat.No: T27613

Target: STAT

Cat.No: T20626

Target: Proton pump, Cysteine Protease

MARK4 inhibitor 1

Cat.No: T11947

Target: Apoptosis, Others, AMPK

Cat.No: T6011

Synonym: 巴马司他,BB94

Target: MMP

Wnt/β-catenin agonist 2

Cat.No: T41094

Target: GSK-3, Wnt/beta-catenin

Cat.No: T9732

Target: Fatty Acid Synthase

Cat.No: T9205

Target: Phosphatase, Others

Cat.No: T15574

Synonym: COL-3,CMT-3

Target: MMP

Cat.No: T12731

Target: RIP kinase

Cat.No: T3710

Target: Tyrosinase, PPAR

Cat.No: T10426

Target: ALK

Cat.No: T26629

Synonym: A-6,A 6 peptide,A6,A 6,A6 peptide,A-6 peptide

Target: PAI-1

Cat.No: T14496

Synonym: ITPKA-IN-C14

Target: Others

Cat.No: TP1472

Target: Others

Gadoxetate Disodium

Cat.No: T15367

Synonym: Gd-EOB-DTPA Disodium,钆塞酸二钠,ZK 139834

Target: Others

Cat.No: T16549

Target: VEGFR

Cat.No: T84314

Target: Apoptosis

Cat.No: T29231

Synonym: ZLD-1039,ZLD 1039

Target: Histone Methyltransferase

Cat.No: T10904

Target: Wnt/beta-catenin

Cat.No: T27371

Synonym: FR167356,FR 167356

Target: ATPase

Cat.No: T12006

Synonym: ML246

Target: DNA/RNA Synthesis

Cat. No.	Product Name	Target	Signaling Pathways
TN1046	Murrayone	Others	Others
	Murrayone 是一种提取自M. paniculata 中的含有香豆素的化合物。Murrayone 具有独特的药理特性，可用作防止癌症转移的化学预防剂。
T3862	Irigenin	NF-κB; Integrin	Cytoskeletal Signaling; NF-κB
	Irigenin 可通过特异性和选择性地阻断 Extra Domain A 域的 C-C 环上α9β1和α4β1整合素结合位点，介导其抗转移作用。可通过增强胃癌细胞中促凋亡分子的表达来敏化 TRAIL 诱导的凋亡，具有抗癌作用。
T2786	Oxysophocarpine 氧化槐树碱,氧卡地平	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Oxysophocarpine 是提取自海藻的生物碱。它对中枢神经系统和周围神经系统具有神经保护作用和抗伤害感受作用。
T3860	Isoliquiritin apioside	MMP; p38 MAPK; NF-κB	MAPK; NF-κB; Proteases/Proteasome
	Isoliquiritin apioside 可抑制癌细胞和内皮细胞的侵袭和血管生成，显著降低 PMA 诱导的MMP9活性增加，并抑制 PMA 诱导的MAPK 和NF-κB 活化。
T4S0969	Obtusifolin 决明蒽醌,决明蒽醌；美决明子素	Antioxidant; NF-κB	NF-κB; oxidation-reduction
	Obtusifolin 是分离自决明子的种子中，能够抑制NF-kB 通路，调节气道上皮细胞中 MUC5AC 粘蛋白的基因表达和产生。它通过靶向甲状旁腺激素相关蛋白来抑制邻苯二甲酸酯诱导的乳腺癌骨转移。
T1181	Gefitinib ZD1839,吉非替尼	EGFR; Tyrosine Kinases; Autophagy	Angiogenesis; Autophagy; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Gefitinib (ZD1839) 是一种 EGFR 一代抑制剂，具有口服活性，抑制 EGFR 19 Del 和 L858R 突变。Gefitinib 具有抗肿瘤活性，用于治疗 EGFR 突变的非小细胞肺癌。Gefitinib 用药会产生 EGFR C797S 耐药突变。
T2982	Xanthone Genicide,呫吨酮,氧杂蒽酮,Xanthenone,Benzophenone oxide	Apoptosis; Others; Influenza Virus; Antibacterial; Antifungal	Apoptosis; Microbiology/Virology; Others
	Xanthone (Xanthenone) 是一种从山竹果中分离得到的天然产物，具有抗炎，抗氧化，抗肿瘤，抗过敏，抗细菌，抗真菌和抗病毒活性。在癌变的不同阶段可控制细胞分裂和生长，凋亡，炎症和转移。
T8169	Decursinol	Others	Others
	Decursinol 是一种分离自Angelica gigas 的根中的、口服具有活性的抗伤害药物。它具有抗肿瘤和抗转移作用。
T6S1676	Cimigenoside	Others; Gamma-secretase	Neuroscience; Others; Proteases/Proteasome; Stem Cells
	Cimigenoside 是升麻属中的一种成分,是一种 γ-分泌酶抑制剂，通过 γ-分泌酶/Notch 轴抑制人类乳腺癌细胞的增殖或转移。
T4S1383	Escin IA Aescin IA,Escin IA;Aescin IA,Escin IA	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Escin IA (Escin IA;Aescin IA);Aescin IA 是从马蹄中七叶树分离出的一种三萜皂苷，抑制HIV-1蛋白酶，IC50值为 35 μM。它具有抗 TNBC 转移活性，其作用机制涉及通过下调 LOXL2 表达抑制上皮-间质转化过程。
T3402	20(S)-Ginsenoside Rg3 20(S)-人参皂苷 Rg3,人参皂苷 Rg3,20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3	EGFR; Beta Amyloid; Potassium Channel; NF-κB; COX; Sodium Channel; Endogenous Metabolite	Angiogenesis; Immunology/Inflammation; JAK/STAT signaling; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB; Tyrosine Kinase/Adaptors
	20(S)-Ginsenoside Rg3 (Rg3) 是红参的主要成分，通过抑制肿瘤细胞的粘附和侵袭来抑制肿瘤细胞肺转移。它抑制Na+和hKv1.4通道，IC50分别为 32.2±4.5 和 32.6±2.2 μM。它还抑制Aβ，NF-κB 活性和COX-2表达，抑制人脐静脉内皮细胞的增殖并具有抗血管生成活性。
TN1982	Neoglycyrol	Others	Others
	Neoglycyrol 是分离自甘草的根中的化合物。它是由传统专利药通脉养心丸中筛选得到，具有潜在心肌保护作用。
T5244	Aminomalonic acid 2-Aminopropanedioic Acid,氨基丙二酸,Aminomalonate	Others; Endogenous Metabolite	Metabolism; Others
	Aminomalonic acid 是氨基内源性代谢产物，在体外能作为来源 Leukemia 5178Y/AR 和小鼠胰腺的L- 天冬酰胺合成酶的高效抑制剂 (Leukemia 5178Y/AR:Ki= 0.0023 M，小鼠胰腺:Ki= 0.0015 M)。它有潜力用作区分黑素瘤转移的不同阶段生物标志物。
T4S1050	Pristimerin 扁塑藤素,Celastrol methyl ester	NF-κB; Antibacterial	Microbiology/Virology; NF-κB
	Pristimerin (Celastrol methyl ester) 是一种可逆的单酰基甘油脂肪酶高效抑制剂，IC50值为93 nM。
T75643	Isoxanthohumol	HSV	Microbiology/Virology
	Isoxanthohumol 是一种从啤酒花和啤酒中提取的一种前黄酮类化合物，对几种人类癌细胞株具有抗增殖活性。Isoxanthohumol对肿瘤细胞肺转移灶的转移或侵袭有抑制作用。Isoxanthohumol具有抗病毒活性，对疱疹病毒（HSV1和HSV2）和牛病毒性腹泻病毒（BVDV）具有抑制作用。
T3403	Glabridin 光甘草定,Q-100692,KB-289522,LS-176045	Reactive Oxygen Species; Tyrosinase; GABA Receptor; Antibacterial; PPAR	DNA Damage/DNA Repair; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; NF-κB; Proteases/Proteasome
	Glabridin (KB-289522) 能够结合并激活PPARγ，EC50值为 6115 nM，是一种从Glycyrrhiza glabra 中分到的异黄烷类天然产物。它具有抗炎、抗菌、抗肾炎、抗氧化、抗肿瘤、抗糖尿病、抗骨质疏松、保护神经、保护心血管、清除自由基等作用。
T6S1699	Shogaol [6]-Shogaol,姜烯酚,6-姜烯酚,6-Shogaol	Lipoxygenase; Autophagy	Autophagy; Metabolism
	6-Shogaol (6-Shogaol) 是从生姜中分离的一种天然产物，具有抗癌、抗炎和抗氧化的多种生物活性。
T5S0055	Chelidonine Helidonine,Khelidonin,白屈菜碱,Stylophorin	Apoptosis; Others; Influenza Virus	Apoptosis; Microbiology/Virology; Others
	Chelidonine (Stylophorin) 是白屈菜中的一种异喹啉生物碱，有抗肿瘤和抗病毒作用。它可导致细胞周期 G2/M 停滞，诱导 caspase 依赖和非依赖性的细胞凋亡。
T23773	Barbigerone Barubigeron
	Barbigerone is a tumor angiogenesis, growth, and metastasis inhibitor in melanoma.
TN5901	Cudratricusxanthone A
	Cudratricusxanthone A has potent anti-proliferative, antioxidative, and monoamine oxidase inhibitory effects, it also possesses anti-cancer activities and provide a basis for developing effective therapeutic agents to inhibit growth and metastasis of brea
TN4166	Griffipavixanthone	ERK; Raf; ROS; MEK; Caspase	Apoptosis; Immunology/Inflammation; MAPK; Proteases/Proteasome
	Griffipavixanthone inhibits the growth of human Non-small-cell lung cancer H520 cells in dose- and time-dependent manners, it induces cell apoptosis through mitochondrial apoptotic pathway accompanying with ROS production. It can inhibit tumor metastasis
T19978	Puromycin NSC 3055,NSC3055,Puromycine,嘌呤霉素,NSC-3055	Antibiotic	Microbiology/Virology
	Puromycin (NSC-3055) 是一种抗生素蛋白质合成抑制剂。它通过与 RNA 结合来抑制蛋白质合成。它还通过 Akt 磷酸化抑制食道癌细胞的生长和转移而用作抗癌药物。它是一种抗肿瘤剂和抗锥虫剂，在研究中用作蛋白质合成的抑制剂。
T71471	Chrysotobibenzyl	Others	Others
	Chrysotobibenzyl, a bibenzyl found in the stem of Dendrobium pulchellum, may facilitate anoikis--a form of programmed cell death that occurs in anchorage-dependent cells when they detach from the surrounding extracellular matrix (ECM)-- and inhibit the growth of lung cancer cells in anchorage-independent condition. Preliminary data obtained discloses the inhibitory effect on cancer cell metastasis of the isolated compounds and may provide a new approach for cancer drug development.
TN3587	Capillarisin	MMP; ERK; IL Receptor; BCL; VEGFR; TNF; NOS; NF-κB; TLR; MAPK; COX; DNA/RNA Synthesis; Prostaglandin Receptor; JNK; STAT	Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; JAK/STAT signaling; MAPK; Neuroscience; NF-κB; Proteases/Proteasome; Stem Cells; Tyrosine Kinase/Adaptors
	Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cells, it inhibits cancer cell growth of osteosarcoma cells by inducing apoptosis accompanied with
TN4300	Isojacareubin	MAPK; PKC; Antifection	Chromatin/Epigenetic; Cytoskeletal Signaling; MAPK; Microbiology/Virology
	Isojacareubin displays potent activity against H. pylori HP40 clinical isolate with MIC 23.9 uM, which is approximately two times greater than that of the standard drug amoxicillin. Isojacareubin is a potent inhibitor of protein kinase C (PKC), suppresses
T3229	Cytochalasin D	ATPase; p38 MAPK; Calcium Channel; Akt; PI3K	Cytoskeletal Signaling; MAPK; Membrane transporter/Ion channel; Metabolism; PI3K/Akt/mTOR signaling
	Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertilization processes such as sperm penetration or sperm head decondensation. Cytochalasin D inhibit
T35624	Ajoene	Others	Others
	Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities, including antibacterial, anticancer, antiplatelet, and antioxidant properties.1,2,3,4It is active against Gram-positive (MICs = 5-160 &#181g/ml) and Gram-negative bacteria (MICs = 136-200 &#181g/ml), as well as yeasts (MICs = 10-20 &#181g/ml).1Ajoene is cytotoxic to mouse melanoma cells (IC50= 18 &#181M), as well as human colon, lung, mammary, and pancreatic cancer cells (IC50s = 7-41 &#181M).2It reduces...

天然产物

Cat.No: TN1046

Target: Others

Cat.No: T3862

Target: NF-κB, Integrin

Oxysophocarpine

Cat.No: T2786

Synonym: 氧化槐树碱,氧卡地平

Target: Prostaglandin Receptor

Isoliquiritin apioside

Cat.No: T3860

Target: MMP, p38 MAPK, NF-κB

Cat.No: T4S0969

Synonym: 决明蒽醌,决明蒽醌；美决明子素

Target: Antioxidant, NF-κB

Cat.No: T1181

Synonym: ZD1839,吉非替尼

Target: EGFR, Tyrosine Kinases, Autophagy

Cat.No: T2982

Synonym: Genicide,呫吨酮,氧杂蒽酮,Xanthenone,Benzophenone oxide

Target: Apoptosis, Others, Influenza Virus, Antibacterial, Antifungal

Cat.No: T8169

Target: Others

Cat.No: T6S1676

Target: Others, Gamma-secretase

Cat.No: T4S1383

Synonym: Aescin IA,Escin IA;Aescin IA,Escin IA

Target: HIV Protease

20(S)-Ginsenoside Rg3

Cat.No: T3402

Synonym: 20(S)-人参皂苷 Rg3,人参皂苷 Rg3,20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3

Target: EGFR, Beta Amyloid, Potassium Channel, NF-κB, COX, Sodium Channel, Endogenous Metabolite

Cat.No: TN1982

Target: Others

Aminomalonic acid

Cat.No: T5244

Synonym: 2-Aminopropanedioic Acid,氨基丙二酸,Aminomalonate

Target: Others, Endogenous Metabolite

Cat.No: T4S1050

Synonym: 扁塑藤素,Celastrol methyl ester

Target: NF-κB, Antibacterial

Cat.No: T75643

Target: HSV

Cat.No: T3403

Synonym: 光甘草定,Q-100692,KB-289522,LS-176045

Target: Reactive Oxygen Species, Tyrosinase, GABA Receptor, Antibacterial, PPAR

Cat.No: T6S1699

Synonym: [6]-Shogaol,姜烯酚,6-姜烯酚,6-Shogaol

Target: Lipoxygenase, Autophagy

Cat.No: T5S0055

Synonym: Helidonine,Khelidonin,白屈菜碱,Stylophorin

Target: Apoptosis, Others, Influenza Virus

Cat.No: T23773

Synonym: Barubigeron

Cudratricusxanthone A

Cat.No: TN5901

Griffipavixanthone

Cat.No: TN4166

Target: ERK, Raf, ROS, MEK, Caspase

Cat.No: T19978

Synonym: NSC 3055,NSC3055,Puromycine,嘌呤霉素,NSC-3055

Target: Antibiotic

Chrysotobibenzyl

Cat.No: T71471

Target: Others

Cat.No: TN3587

Target: MMP, ERK, IL Receptor, BCL, VEGFR, TNF, NOS, NF-κB, TLR, MAPK, COX, DNA/RNA Synthesis, Prostaglandin Receptor, JNK, STAT

Cat.No: TN4300

Target: MAPK, PKC, Antifection

Cat.No: T3229

Target: ATPase, p38 MAPK, Calcium Channel, Akt, PI3K

Cat.No: T35624

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02384	MTSS1 Protein, Human, Recombinant (aa1-250, His & MBP) metastasis suppressor 1,MIMB,MIM,MIMA	Human	E. coli
	MTSS1 (Metastasis suppressor 1), also known as Missing in metastasis (MIM), is a tissue-specific regulator of plasma membrane dynamics. MTSS1 is well described for its function as a metastasis suppressor gene and is expressed in a variety of tissues. MTSS1 might be involved in shaping neuronal membranes in vivo. MTSS1 deforms phosphoinositide-rich membranes through its I-BAR domain and interacts with actin monomers through its WH2 domain. MTSS1/MIM was first identified as a metastasis suppressor...
TMPJ-00708	CST7 Protein, Mouse, Recombinant (His) CMAP,Cystatin-7,Leukocystatin,Cystatin-like Metastasis	Mouse	HEK293 Cells
	Mouse Cystatin F belongs to cystatin superfamily, which encompasses proteins that contain multiple cystatin-like sequences. It has been shown that Cystatin F is selectively expressed by hematopoietic cells and may be a biomarker for both liver metastasis and inflammatory lung disorders. Mouse Cystatin F inhibits papain and cathepsin L but with affinities lower than other cystatins. It may play a role in immune regulation through inhibition of a unique target in the hematopoietic system.
TMPJ-00025	CST7 Protein, Human, Recombinant (His) Cystatin-7,CST7,Leukocystatin,Cystatin-F,CMAP,Cystatin-Like ...	Human	HEK293 Cells
	CST7 is a secreted protein and primarily expressed in peripheral blood cells and spleen.It is belongs to the cystatin family. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2...
TMPY-02030	CD82 Protein, Human, Recombinant (His) CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,TSPAN27,ST6,IA4,GR1...	Human	HEK293 Cells
	CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud...
TMPK-00022	Galectin-1 Protein, Human, Recombinant (hFc) GAL1,LGALS1,Galectin-1,S-Lac lectin 1,DKFZp686E23103,GBP,Gal...	Human	HEK293 Cells
	Galectin 1 (Gal-1), a β-galactoside binding mammalian lectin of 14KDa, is implicated in many signalling pathways, immune responses associated with cancer progression and immune disorders. Inhibition of human Gal-1 has been regarded as one of the potential therapeutic approaches for the treatment of cancer, as it plays a major role in tumour development and metastasis by modulating various biological functions viz. apoptosis, angiogenesis, migration, cell immune escape.
TMPK-00305	TGFBR1 Protein, Human, Recombinant (mFc & Avi) tbetaR-I,TGFβRI,TGFbetaRI,LDS2A,ALK-5,TGF-beta RI,tβR-I,TGF-...	Human	HEK293 Cells
	transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1.
TMPY-00476	ITGB1 Protein, Human, Recombinant (His) VLAB,integrin, beta 1 (fibronectin receptor, beta polypeptid...	Human	HEK293 Cells
	ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involved in cell functions such as proliferation, migration, invasion, and survival. ITGB1 has been recognized to play a major role in tumor growth, invasion, and metastasis. Using luciferase assays, the researcher identified ITGB1 as a direct target of miR-134. ITGB1 is a direct targe...
TMPY-00566	CCL18 Protein, Human, Recombinant (His) PARC,CCL18,CKb7,DC-CK1,chemokine (C-C motif) ligand 18,MIP-4...	Human	P. pastoris (Yeast)
	CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its potential as a circulating biomarker. CCL18 chemokine has an important role in chemokine-mediated tumor metastasis, and may serve as a potential predictor for poor survival outcomes for ovarian cancer. (CCL18) is predominantly secreted by M2-tumor associated macrophages (TAMs) a...
TMPY-02028	RON/CD136 Protein, Human, Recombinant (His) CD136,macrophage stimulating 1 receptor,CDw136,PTK8,RON	Human	HEK293 Cells
	The tyrosine kinase receptor, macrophage-stimulating 1 receptor (MST1R), a c-met-related tyrosine kinase, also known as the Ron receptor or CD136, controls cell survival and motility programs related to invasive growth. As the tyrosine kinase receptor is comprised of an extracellular domain, MST1R protein contains the ligand-binding pocket and an intracellular region where the kinase domain is located. MST1R signaling may be involved in the regulation of macrophage and T-lymphocyte activation in...
TMPY-04467	NME1 Protein, Human, Recombinant (His) NME/NM23 nucleoside diphosphate kinase 1,NB,NDPK-A,NM23-H1,N...	Human	E. coli
	NME1, also known as Nucleoside Diphosphate Kinase A (NDK-A), or NM23-H1, belongs to the NDK family. NM23-H1 is known to have a metastasis suppressive activity in many tumor cells. Recent studies have shown that the interacting proteins with NM23-H1 which mediate cell proliferation, may act as modulators of the metastasis suppressor activity. The interacting proteins with NM23-H1 can be classified into 3 groups. The first group of proteins can be classified as upstream kinases of NM23-H1 such as ...
TMPK-00293	Nectin-2 Protein, Human, Recombinant (His & Avi) PRR2,CD112,Nectin2,MPH,PVRR2,PVRL2,HVEB	Human	HEK293 Cells
	Nectin-2 is an adhesion molecule that has been reported to play a role in tumor growth, metastasis and tumor angiogenesis. Nectin-2 expression in ovarian cancer may support tumor cell adhesion, leading to growth and lymph node metastasis. Effect of VEGF on Nectin-2 expression as well as permeability was investigated in HUVEC.
TMPK-00865	TM4SF1 Protein-VLP, Human, Recombinant TAAL6,L6,H-L6,M3S1	Human	HEK293 Cells
	Transmembrane-4-L-six-family-1(TM4SF1), a four-transmembrane L6 family member, is highly expressed in various pancreatic cancer cell lines and promotes cancer cells metastasis. It is upregulated in several epithelial cancers and is closely associated with poor prognosis.
TMPK-00742	PRL-3/PTP4A3 Protein, Human, Recombinant (His) PRL-R,PRLR,PRL3,PTP4A3,PRL-3	Human	E. coli
	Phosphatases of regenerating liver (PRL-1, PRL-2, and PRL-3, also known as PTP4A1, PTP4A2, and PTP4A3) control magnesium homeostasis through an association with the CNNM magnesium transport regulators. PTP4A3 (PRL-3) plays an important role in the tumorigenesis and metastasis of multiple tumors.
TMPH-01060	Cathepsin F Protein, Human, Recombinant (His) Cathepsin F,CTSF,CATSF	Human	E. coli
	Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. Cathepsin F Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 27.4 kDa and the accession number is Q9UBX1.
TMPK-00820	AREG Protein, Human, Recombinant (hFc) SDGF,AR,MGC13647,AREGB,CRDGF,Amphiregulin,AREG	Human	HEK293 Cells
	Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and is expressed in a plethora of cancers. Tumour growth and metastasis were decreased by AREG silencing in an orthotopic model of pancreatic cancer. AREG may play a critical role in cell migration, invasion, and EMT by activating the EGFR/ERK/NF‑κB signalling pathway in pancreatic cancer cells.
TMPJ-00050	AG-3 Protein, Human, Recombinant (His) BCMP11,hAG-3,AG-3,AG3,Anterior Gradient Protein 3 Homolog,Br...	Human	HEK293 Cells
	Anterior Gradient Protein 2(AG-2) and Anterior Gradient Protein 3 (AG-3) are human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan (hAG-3 protein). AG-3 could serve as a prognostic marker for survival in patients with low grade and high grade serous ovarian carcinomas.
TMPK-01028	BSPII Protein, Mouse, Recombinant (His) IBSP,SP II,BSP,BSP II,BNSP,BSP-II,BSP 2,SPII,SP-II	Mouse	HEK293 Cells
	Osteopontin (OPN), bone sialoprotein (BSPII), and osteonectin (ON) belong to a family of glycoproteins, which have been linked to cancer metastasis and progression. Here, we report on the selection of antisense oligonucleotides (ASOs), which are effective in reducing their protein levels.
TMPK-01256	CDCP1 Protein, Cynomolgus, Recombinant (His) TRASK,SIMA135,UNQ2486,CD318,PRO5773,CDCP1	Cynomolgus	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression. CDCP1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 73.2 kDa and the accession number is F6TPM5.
TMPJ-00159	EMMPRIN/CD147 Protein, Human, Recombinant (Avi & His), Biotinylated Membrane glycoprotein gp42,Basigin,HT7 antigen,Bsg,Basic imm...	Human	HEK293 Cells
	Basigin/CD147 is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore...
TMPK-01132	PRL-1/PTP4A1 Protein, Human, Recombinant (His) PTPCAAX1,PRL1,PRL-1,PTP(CAAXI),PTP4A1	Human	E. coli
	Phosphatases of regenerating liver (PRL-1, PRL-2, and PRL-3, also known as PTP4A1, PTP4A2, and PTP4A3) control magnesium homeostasis through an association with the CNNM magnesium transport regulators. PRL-1 (PTP4A1) is a key molecule that activates tyrosine phosphorylation, which is important for cancer progression and metastasis.
TMPK-01183	CDCP1 Protein, Human, Recombinant (aa 30-368, His) CDCP1,PRO5773,TRASK,CD318,UNQ2486,SIMA135	Human	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression. CDCP1 Protein, Human, Recombinant (aa 30-368, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 39.03 kDa and the accession number is Q9H5V8-1.
TMPK-00260	CD155/PVR Protein, Human, Recombinant (His & Avi) NECL5,PVSFLJ25946,Necl-5,CD155,Tage4,PVR,HVED,FLJ25946,necti...	Human	HEK293 Cells
	CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells to induce their cytotoxicity. CD155 is also commonly referred to as the "poliovirus receptor," or PVR.
TMPK-00829	Galectin-1 Protein, Mouse, Recombinant (hFc) GBP,DKFZp686E23103,S-Lac lectin 1,GAL1,Galectin-1,HLBP14,LGA...	Mouse	HEK293 Cells
	Galectin 1(Gal-1), a β-galactoside binding mammalian lectin of 14KDa, is implicated in many signalling pathways, immune responses associated with cancer progression and immune disorders. Inhibition of human Gal-1 has been regarded as one of the potential therapeutic approaches for the treatment of cancer, as it plays a major role in tumour development and metastasis by modulating various biological functions viz. apoptosis, angiogenesis, migration, cell immune escape.
TMPK-01188	CHODL Protein, Human, Recombinant (hFc) PRED12,C21orf68,CHODL,MT75,Chondrolectin,3110074E07Rik,FLJ12...	Human	HEK293 Cells
	chondrolectin (CHODL) is commonly overexpressed in the majority of lung cancers, indicating a possible correlation between CHODL and metastasis of lung cancer cells. the expression of CHODL is significantly decreased in HCC clinical samples and in HCC cell lines. Overexpression of CHODL in SMMC7721 cells with a lentiviral vector increased SMMC7721 cell migration and invasion.
TMPY-01584	PR-Set7 Protein, Human, Recombinant SET8,SET07,PR-Set7,SET domain containing (lysine methyltrans...	Human	E. coli
	KMT5A (known as PR-Set7/9, SETD8 and SET8), a member of the SET domain containing methyltransferase family specifically targeting H4K20 for methylation, has been implicated in multiple biological processes. Inhibition of KMT5A attenuated proliferation and induced apoptosis. Elevated KMT5A expression was significantly correlated with extrathyroidal extension, lymph node metastasis and advanced pathological stage of papillary thyroid cancer. KMT5A may be a novel oncogenic factor, specifically a re...
TMPK-01255	CDCP1 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated TRASK,SIMA135,UNQ2486,PRO5773,CD318,CDCP1	Cynomolgus	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression. CDCP1 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 75 kDa and the accession number is...
TMPK-00635	CDCP1 Protein, Rat, Recombinant (His) TRASK,SIMA135,UNQ2486,CD318,PRO5773,CDCP1	Rat	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression. CDCP1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 73.09 kDa and the accession number is D3ZVA1.
TMPK-01182	CDCP1 Protein, Human, Recombinant (hFc) CDCP1,PRO5773,TRASK,UNQ2486,SIMA135,CD318	Human	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression. CDCP1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 98.4 kDa and the accession number is Q9H5V8-1.
TMPY-03795	EIF5A2 Protein, Human, Recombinant (His) eIF5AII,eukaryotic translation initiation factor 5A2,EIF-5A2	Human	E. coli
	Eukaryotic translation initiation factor 5A2 (EIF5A2) has been demonstrated to be upregulated in numerous types of human cancer and is associated with cancer progression. Silencing of EIF5A2 in the NSCLC cells resulted in the downregulation of the tumorigenic proteins, apoptosis regulator Bcl-2 and myc proto-oncogene protein, and upregulation of E-cadherin, suggesting that EIF5A2 promotes proliferation and metastasis through these proteins. EIF5A2 may therefore serve as a novel therapeutic targe...
TMPK-00410	AXL Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated ARK,EC 2.7.10.1,EC 2.7.10,Axl,JTK11,AXL oncogene,UFO,AI32364...	Human	HEK293 Cells
	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein (Primary Amine Labeling), Human, Rec...
TMPK-01010	CDCP1 Protein, Mouse, Recombinant (His & Avi), Biotinylated UNQ2486,TRASK,CD318,SIMA135,CDCP1,PRO5773	Mouse	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression. CDCP1 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 75.3 kDa and the accession number is Q5...
TMPK-00899	EPHA5 Protein, Human, Recombinant (His) HEK7,EK7,Rek7,EphA5,EHK1,TYRO4HEK7CEK7,TYRO4,BSK,EHK-1	Human	HEK293 Cells
	Ephrin type-A receptor 5 (EphA5) expression was detected in all non-tumor gastric epithelia but was differentially expressed among gastric cancer samples. EphA5 is differentially expressed in gastric cancer. EphA5 may therefore be a potential therapeutic target and may have clinical utility as a marker for lymph node metastasis in gastric cancer. EPHA5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 61.9 kDa and the acces...
TMPK-01225	MRC2 Protein, Human, Recombinant (His) C-type lectin domain family 13 member E, Endocytic receptor ...	Human	HEK293 Cells
	MRC2 (Mannose Receptor C Type 2) is a constitutively recycling endocytic receptor belonging to the mannose receptor family, which has been found to be closely involved with cancer metastasis. MRC2 expresses an extracellular fibronectin type II domain that binds to and internalizes collagen, suggesting that it may play a role in modulating renal fibrosis. MRC2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.64 kDa and t...
TMPH-01059	Cathepsin B Protein, Human, Recombinant (GST) Cathepsin B1,APPS,Cathepsin B,CPSB,APP secretase,CTSB	Human	E. coli
	Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen. Has also been implicated in tumor invasion and metastasis. Cathepsin B Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 54.6 kDa and the accession number is P07858.
TMPJ-00561	SDC2 Protein, Human, Recombinant (His) CD362,SDC2,HSPG,HSPG1,Syndecan-2,SYND2,Heparan Sulfate Prote...	Human	HEK293 Cells
	Syndecan-2 is a member of the Syndecans family comprised of type I transmembrane heparan sulfate proteoglycans (HSPG) that are involved in the regulation of many cellular processes. Four sub-types of mammalian Syndecans have been reported and among them. Syndecan-2 plays a role in the cancer development. It can affect the basal and chemotherapy-induced apoptosis in osteosarcoma. It can also suppress MMP2 activation, suppressing metastasis.
TMPK-00574	MRC2 Protein, Canine, Recombinant (His) Mannose receptor C type 2	Canine	HEK293 Cells
	MRC2 (Mannose Receptor C Type 2) is a constitutively recycling endocytic receptor belonging to the mannose receptor family, which has been found to be closely involved with cancer metastasis. MRC2 expresses an extracellular fibronectin type II domain that binds to and internalizes collagen, suggesting that it may play a role in modulating renal fibrosis. MRC2 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.76 kDa and ...
TMPK-00529	EPHA5 Protein, Cynomolgus, Recombinant (His) EHK-1,BSK,Rek7,EK7,EphA5,HEK7,TYRO4,TYRO4HEK7CEK7,EHK1	Cynomolgus	HEK293 Cells
	Ephrin type-A receptor 5 (EphA5) expression was detected in all non-tumor gastric epithelia but was differentially expressed among gastric cancer samples. EphA5 is differentially expressed in gastric cancer. EphA5 may therefore be a potential therapeutic target and may have clinical utility as a marker for lymph node metastasis in gastric cancer. EPHA5 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 61.73 kDa and the...
TMPK-00172	B7-H4 Protein, Human, Recombinant (His & Avi) B7H4,B7x,VTCN1,PRO1291,B7S1,B7h.5,FLJ22418,B7-H4	Human	HEK293 Cells
	B7-H4, also known as B7x and B7S1, is a 50-80 kDa glycosylated member of the B7 family of immunomodulatory proteins.B7-H4 is up-regulated in several carcinomas in correlation with tumor progression and metastasis. A soluble form of B7-H4 is elevated in the serum of ovarian cancer, renal cell carcinoma, and rheumatoid arthritis patients, also in correlation with advanced disease status .
TMPJ-01137	MIA Protein, Human, Recombinant (His) MIA,Melanoma Inhibitory Activity Protein,Melanoma-Derived Gr...	Human	E. coli
	Melanoma Inhibitory Activity Protein (MIA) is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells, which was the first discovered member of a family of secreted cytokines termed the MIA/OTOR family. The four known members of this family: MIA, MIA2, OTOR and TANGO each contain a Src homology-3 (SH3)-like domain. MIA acts as a potent tumor cell growth inhibitor for malignant melanoma cells and some other neuroectodermal tumors, including gliomas, in an au...
TMPY-05068	PDGFA Protein, Rat, Recombinant (His) 血小板源生长因子,platelet-derived growth factor alpha polypeptide,pl...	Rat	P. pastoris (Yeast)
	Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site. PDG...
TMPY-05075	PDGFA Protein, Canine, Recombinant (His) platelet-derived growth factor α polypeptide,血小板源生长因子,platel...	Canine	P. pastoris (Yeast)
	Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site. PDG...
TMPY-04387	AKT2 Protein, Human, Recombinant (His & GST) RAC-β,RAC-BETA,HIHGHH,PKBBETA,PKBβ,PRKBB,PKBB,v-akt murine t...	Human	Baculovirus Insect Cells
	AKT (AK mouse plus Transforming or Thymoma) is a frequent oncogene expressed in most tissues which includes three isoforms AKT1, AKT2, and AKT3. Hyperactivation of AKT signaling is a central key in many human cancer progressions, through modulating angiogenesis, tumor growth, and cell migration, invasion, metastasis, and chemoresistance. Among all three isoforms, AKT2 is most related to cancer cell invasion, metastasis, and survival. Amplification and overexpression of AKT2 have been shown in ma...
TMPK-00340	ALCAM Protein, Human, Recombinant (His & Avi), Biotinylated CD166,CD6L,KG-CAM,ALCAM,MEMD	Human	HEK293 Cells
	Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression promote BM formation in NSCLC through increased tumor cell dissemination and interaction with the brain endothelial cells. Therefore, ALCAM could be targeted to reduce the occurrence of BM. ALCAM Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian...
TMPK-00408	AXL Protein, Human, Recombinant (His & Avi), Biotinylated AXL oncogene,EC 2.7.10.1,AI323647,Axl,JTK11,ARK,EC 2.7.10,UF...	Human	HEK293 Cells
	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein, Human, Recombinant (His & Avi), Bio...
TMPK-00812	Midkine Protein, Mouse, Recombinant (His) MK1,ARAP,MKARAP,MEK,MK,NEGF2,MDK	Mouse	E. coli
	Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Mo...
TMPK-01181	CDCP1 Protein, Human, Recombinant (His & Avi), Biotinylated CDCP1,PRO5773,TRASK,UNQ2486,SIMA135,CD318	Human	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression. CDCP1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 74.6 kDa and the accession number is Q9...
TMPJ-00508	CTSL Protein, Human, Recombinant (His) CTSL,CTSL1,Cathepsin L1,Major Excreted Protein,MEP	Human	HEK293 Cells
	Cathepsin L is an enzyme. Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L plays a major role in antigen processing, tumor invasion and metastasis, bone resorption, and turnover of intracellular and secreted proteins involved in growth regulation. Unlike the precursor forms of other papain family members, the 43 kDa pro-cathepsin L itself is secreted from various cells. Pro-cathepsin L is the maj...
TMPK-00052	IL-20 Protein, Human, Recombinant (His) 白细胞介素,MGC96907,Zcyto10,IL-20,白介素,IL10D,Cytokine Zcyto10	Human	HEK293 Cells
	Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progression has not yet been investigated. In addition, IL-20 expression was significantly associated with tumor size, metastasis, TNM stage and poor prognosis in patients with HCC. IL-20 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predic...
TMPK-00341	ALCAM Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated ALCAM,KG-CAM,MEMD,CD166,CD6L	Human	HEK293 Cells
	Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression promote BM formation in NSCLC through increased tumor cell dissemination and interaction with the brain endothelial cells. Therefore, ALCAM could be targeted to reduce the occurrence of BM. ALCAM Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed ...
TMPK-00957	MFAP5 Protein, Human, Recombinant (hFc) MAGP2,AAT9,MAGP-2,MP25,MFAP-5	Human	HEK293 Cells
	Human basal-like breast cancer (BLBC) is an aggressive malignancy with poor prognosis. Since most current treatments are ineffective, there is an urgent need to identify therapeutic targets for BLBC. Microfibrillar-associated protein 5 (MFAP5) plays an important role in the integration of elastic microfibers and the regulation of endothelial cell behaviors.MFAP5 was significantly overexpressed in BLBC tissues and associated with poor metastasis-free survival of patients with BLBC. MFAP5 Protein,...
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重组蛋白

MTSS1 Protein, Human, Recombinant (aa1-250, His & MBP)

Cat.No: TMPY-02384

Species: Human

Expression System: E. coli

CST7 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00708

Species: Mouse

Expression System: HEK293 Cells

CST7 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00025

Species: Human

Expression System: HEK293 Cells

CD82 Protein, Human, Recombinant (His)

Cat.No: TMPY-02030

Species: Human

Expression System: HEK293 Cells

Galectin-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00022

Species: Human

Expression System: HEK293 Cells

TGFBR1 Protein, Human, Recombinant (mFc & Avi)

Cat.No: TMPK-00305

Species: Human

Expression System: HEK293 Cells

ITGB1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00476

Species: Human

Expression System: HEK293 Cells

CCL18 Protein, Human, Recombinant (His)

Cat.No: TMPY-00566

Species: Human

Expression System: P. pastoris (Yeast)

RON/CD136 Protein, Human, Recombinant (His)

Cat.No: TMPY-02028

Species: Human

Expression System: HEK293 Cells

NME1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04467

Species: Human

Expression System: E. coli

Nectin-2 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00293

Species: Human

Expression System: HEK293 Cells

TM4SF1 Protein-VLP, Human, Recombinant

Cat.No: TMPK-00865

Species: Human

Expression System: HEK293 Cells

PRL-3/PTP4A3 Protein, Human, Recombinant (His)

Cat.No: TMPK-00742

Species: Human

Expression System: E. coli

Cathepsin F Protein, Human, Recombinant (His)

Cat.No: TMPH-01060

Species: Human

Expression System: E. coli

AREG Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00820

Species: Human

Expression System: HEK293 Cells

AG-3 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00050

Species: Human

Expression System: HEK293 Cells

BSPII Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01028

Species: Mouse

Expression System: HEK293 Cells

CDCP1 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01256

Species: Cynomolgus

Expression System: HEK293 Cells

EMMPRIN/CD147 Protein, Human, Recombinant (Avi & His), Biotinylated

Cat.No: TMPJ-00159

Species: Human

Expression System: HEK293 Cells

PRL-1/PTP4A1 Protein, Human, Recombinant (His)

Cat.No: TMPK-01132

Species: Human

Expression System: E. coli

CDCP1 Protein, Human, Recombinant (aa 30-368, His)

Cat.No: TMPK-01183

Species: Human

Expression System: HEK293 Cells

CD155/PVR Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00260

Species: Human

Expression System: HEK293 Cells

Galectin-1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00829

Species: Mouse

Expression System: HEK293 Cells

CHODL Protein, Human, Recombinant (hFc)

Cat.No: TMPK-01188

Species: Human

Expression System: HEK293 Cells

PR-Set7 Protein, Human, Recombinant

Cat.No: TMPY-01584

Species: Human

Expression System: E. coli

CDCP1 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01255

Species: Cynomolgus

Expression System: HEK293 Cells

CDCP1 Protein, Rat, Recombinant (His)

Cat.No: TMPK-00635

Species: Rat

Expression System: HEK293 Cells

CDCP1 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-01182

Species: Human

Expression System: HEK293 Cells

EIF5A2 Protein, Human, Recombinant (His)

Cat.No: TMPY-03795

Species: Human

Expression System: E. coli

AXL Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated

Cat.No: TMPK-00410

Species: Human

Expression System: HEK293 Cells

CDCP1 Protein, Mouse, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01010

Species: Mouse

Expression System: HEK293 Cells

EPHA5 Protein, Human, Recombinant (His)

Cat.No: TMPK-00899

Species: Human

Expression System: HEK293 Cells

MRC2 Protein, Human, Recombinant (His)

Cat.No: TMPK-01225

Species: Human

Expression System: HEK293 Cells

Cathepsin B Protein, Human, Recombinant (GST)

Cat.No: TMPH-01059

Species: Human

Expression System: E. coli

SDC2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00561

Species: Human

Expression System: HEK293 Cells

MRC2 Protein, Canine, Recombinant (His)

Cat.No: TMPK-00574

Species: Canine

Expression System: HEK293 Cells

EPHA5 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00529

Species: Cynomolgus

Expression System: HEK293 Cells

B7-H4 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00172

Species: Human

Expression System: HEK293 Cells

MIA Protein, Human, Recombinant (His)

Cat.No: TMPJ-01137

Species: Human

Expression System: E. coli

PDGFA Protein, Rat, Recombinant (His)

Cat.No: TMPY-05068

Species: Rat

Expression System: P. pastoris (Yeast)

PDGFA Protein, Canine, Recombinant (His)

Cat.No: TMPY-05075

Species: Canine

Expression System: P. pastoris (Yeast)

AKT2 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04387

Species: Human

Expression System: Baculovirus Insect Cells

ALCAM Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00340

Species: Human

Expression System: HEK293 Cells

AXL Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00408

Species: Human

Expression System: HEK293 Cells

Midkine Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00812

Species: Mouse

Expression System: E. coli

CDCP1 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01181

Species: Human

Expression System: HEK293 Cells

CTSL Protein, Human, Recombinant (His)

Cat.No: TMPJ-00508

Species: Human

Expression System: HEK293 Cells

IL-20 Protein, Human, Recombinant (His)

Cat.No: TMPK-00052

Species: Human

Expression System: HEK293 Cells

ALCAM Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

Cat.No: TMPK-00341

Species: Human

Expression System: HEK293 Cells

MFAP5 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00957

Species: Human

Expression System: HEK293 Cells

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Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0302	Esomeprazole-d3
	Esomeprazole-d3 是 Esomeprazole 的氘代化合物。Esomeprazole 的 CAS 号为 119141-88-7。Esomeprazole 是奥美拉唑(omeprazole) 的S-异构体，抑制溶酶体半胱氨酸蛋白酶legumain，防止癌症转移。它是一种质子泵抑制剂（PPI）。
TMIJ-0099	Minodronic acid-d4
	Minodronic acid-d4 是 Minodronic acid 的氘代化合物。Minodronic acid 的 CAS 号为 180064-38-4。Minodronic acid(YM-529) 是一种 P2X2/3 受体拮抗剂，具有抗癌活性，可直接或间接的抑制癌细胞增殖，诱导细胞凋亡。Minodronic-acid 对各种类型的癌细胞的转移具有抑制作用。Minodronic-acid 可用于研究骨质疏松。
T71293	Nifuroxazide-d4
	Nifuroxazide-d4 is intended for use as an internal standard for the quantification of nifuroxazide by GC- or LC-MS. Nifuroxazide is a nitrofuran antibiotic. It is active against strains of the enteropathogenic bacteria C. jejuni, Salmonella, Y. enterocolitica, Shigella, and E. coli. It inhibits quorum sensing and virulence factor production in P. aeruginosa. Nifuroxazide inhibits STAT3 activity in a reporter assay and decreases viability of U266 and INA-6 myeloma cells, which have constitutive S...

同位素标记化合物

Esomeprazole-d3

Cat.No: TMIJ-0302

Minodronic acid-d4

Cat.No: TMIJ-0099

Nifuroxazide-d4

Cat.No: T71293

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