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Targets Recommended: Glucocorticoid Receptor Mitophagy IL Receptor Annexin A NOS Antibacterial Autophagy ADC Cytotoxin

207

抑制剂 & 化合物

50

天然产物

14

化合物库

334

重组蛋白

2

同位素标记化合物

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Cat. No. Product Name
L2130 抗癌细胞代谢库

1268 compounds
1268 种癌细胞代谢相关的生物活性小分子化合物的特有集合,用于肿瘤相关的研究以及抗肿瘤药物的筛选,用于高通量、高内涵筛选;
L3200 自噬库

1248 compounds
1248 种细胞自噬相关的生物活性小分子化合物的特有集合,用于自噬相关的研究,用于高通量、高内涵筛选;
L1200 表观遗传库

953 compounds
953 种表观遗传学研究相关的生物活性小分子的特有集合,用于表观遗传学研究及其相关的检测和高通量、高内涵筛选;
L4000 经典已知活性库

14439 compounds
14439 个已知活性化合物的集合,可用于高通量筛选、高内涵筛选、细胞诱导和靶点确认;
L3700 JAK-STAT 化合物库

252 compounds
252 个 JAK/STAT 靶点相关的小分子化合物的独特集合,用于高通量、高内涵筛选;
L6140 糖类及苷类化合物库

595 compounds
595 种糖类或苷类的化合物,可用于高通量筛选和高内涵筛选;
L2501 人内源代谢化合物库 Plus

1283 compounds
1283种内源性生物活性化合物的独特集合,用于高通量、高内涵筛选。
L7700 神经再生化合物库

524 compounds
524 种神经再生相关化合物的独特集合,可用于高通量筛选和高内涵筛选;
L2510 脂代谢化合物库

492 compounds
492 个脂代谢相关的化合物集合,可用于高通量和高内涵筛选;
L2610 神经递质受体化合物库

1513 compounds
1513 种与神经递质受体相关的化合物,用于高通量、高内涵筛选;
L2520 糖代谢化合物库

702 compounds
702 种糖代谢相关的化合物,可用于高通量和高内涵筛选;
L8500 HIF-1化合物库

1336 compounds
1336 个HIF-1相关小分子的独特集合,可用于缺血性疾病、癌症等相关领域的药物开发和药理研究;
L2550 谷氨酰胺代谢化合物库

565 compounds
565 种谷氨酰胺代谢相关的分子,可以用于高通量和高内涵筛选;
DO1200 药物靶点库

53200 compounds
数量多,含53200种小分子化合物,是高通量筛选的有力工具;

化合物库

抗癌细胞代谢库
Cat.No: L2130
Compounds: 1268
自噬库
Cat.No: L3200
Compounds: 1248
表观遗传库
Cat.No: L1200
Compounds: 953
经典已知活性库
Cat.No: L4000
Compounds: 14439
JAK-STAT 化合物库
Cat.No: L3700
Compounds: 252
糖类及苷类化合物库
Cat.No: L6140
Compounds: 595
人内源代谢化合物库 Plus
Cat.No: L2501
Compounds: 1283
神经再生化合物库
Cat.No: L7700
Compounds: 524
脂代谢化合物库
Cat.No: L2510
Compounds: 492
神经递质受体化合物库
Cat.No: L2610
Compounds: 1513
糖代谢化合物库
Cat.No: L2520
Compounds: 702
HIF-1化合物库
Cat.No: L8500
Compounds: 1336
谷氨酰胺代谢化合物库
Cat.No: L2550
Compounds: 565
药物靶点库
Cat.No: DO1200
Compounds: 53200
Cat. No. Product Name Target Signaling Pathways
T0947 Dexamethasone acetate

Dexamethasone 21-acetate,醋酸地塞米松,Dexamethason acetate,NSC 39471

Glucocorticoid Receptor; Mitophagy; IL Receptor; Annexin A; NOS; Antibacterial; Autophagy; ADC Cytotoxin Antibody-drug Conjugate/ADC Related; Autophagy; Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology
Dexamethasone acetate (NSC 39471) 是一种糖皮质素类甾体,有抗炎和免疫抑制活性。它可研究眼部感染。
T33885 Parkeyl acetate

Others Others
Parkeyl acetate is a bioactive chemical.
TP1620 Cyclic MKEY

MKEY, a synthetic cyclic peptide inhibitor of CXCL4-CCL5 heterodimer formation, has been shown to protect against atherosclerosis and aortic aneurysm formation by mediating inflammation, but whether it modulates neuroinflammation and brain injury has not
T78011 Cyclic MKEY TFA

Cyclic MKEY TFA为CXCL4-CCL5异二聚体的合成环肽抑制剂,可通过调控炎症反应预防动脉粥样硬化和主动脉瘤。此外,该化合物亦能阻止小鼠中风后脑损伤的发生。
T60011 HS220

MAPK MAPK
HS220 是 TAK1 抑制剂,TAK1 在炎症和细胞存活的信号通路中起关键作用。
T19588 TP748

2-苄氧基恶唑

Others Others
TP748 是一种异恶唑,也是合成四环素的关键中间体。
T20318 Benzylideneaniline

N-苄叉苯胺,N-Benzylideneaniline

Others Others
Benzylideneaniline (N-Benzylideneaniline) 是一种有效的木质芪-α,β-双加氧酶抑制剂,它是氧化裂解木质芪中心双键的关键酶。
T4659 ELN484228

Others Others
ELN484228 是一种 α-突触核蛋白的阻断剂。α-突触核蛋白是帕金森病中的关键蛋白质。
T15140 DLinDMA

Others Others
DLinDMA 是一种稳定的核酸脂质颗粒 (SNALPs) 中的关键脂质成分,是一种可电离的阳离子脂质。它可用于siRNA 递送的研究。
T5015 Gonadorelin Acetate (33515-09-2 free base)

醋酸戈那瑞林,Luteinizing Hormone Releasing Hormone (LH-RH),Luteinizing Hormone Releasing Hormone (LH-RH), human,Gonadorelin Acetate

Reductase Endocrinology/Hormones; Metabolism
Gonadorelin Acetate (33515-09-2 free base) (Luteinizing Hormone Releasing Hormone (LH-RH)) 是下丘脑神经肽,在控制生殖功能中起关键作用。
T0637 2-Acetyl-6-methoxynaphthalene

Others Others
2-Acetyl-6-methoxynaphthalene 是naphthalene tome 和naproxen 的关键中间体,用于合成非甾体抗炎镇痛药。
T12896L Shepherdin 79-87 acetate

Shepherdin 79-87 acetate (861224-28-4 free base)

HSP; Survivin Apoptosis; Cytoskeletal Signaling; Metabolism
Shepherdin 79-87 acetate 是 Hsp90 和 survivin 之间复合物的拟肽拮抗剂,survivin 是肿瘤细胞活力的另一个关键调节剂。
T7201 Nelociguat

N-[4,6-二氨基-2-[1-[(2-氟苯基)甲基]-1H-吡唑并[3,4-B]吡啶-3-基]-5-嘧啶]-氨基甲酸甲酯,BAY60-4552

Guanylate cyclase GPCR/G Protein
Nelociguat (BAY60-4552) 是一种一氧化氮敏感的可溶性鸟苷酸环化酶刺激剂。
T10884 CRAC intermediate 1

5-(S)-Fluorowillardiine

Calcium Channel Membrane transporter/Ion channel; Metabolism
CRAC intermediate 1是用于CRAC离子通道系列化合物合成的关键中间体,详细信息来自专利WO 2010122089。
T29856 Aleplasinin

PAZ 417,PAZ417,PAZ-417

PAI-1 Metabolism
Aleplasinin (PAZ 417) 是纤溶酶原激活物抑制剂 1 (PAI-1) 的选择性和口服活性抑制剂,是纤溶系统的关键负调节剂。 Aleplasinin 可用于阿尔茨海默病研究。
T2280 Endoxifen (Z-isomer)

Z-因多昔芬,Endoxifen Z-isomer,4-[(1E)-1-{4-[2-(甲基氨基)乙氧基]苯基}-2-苯基-1-丁烯-1-基]苯酚

Estrogen Receptor/ERR; EGFR; Potassium Channel; Estrogen/progestogen Receptor; HER Angiogenesis; Endocrinology/Hormones; JAK/STAT signaling; Membrane transporter/Ion channel; Tyrosine Kinase/Adaptors
Endoxifen Z-isomer (EDX)是 Tamoxifen 重要的代谢产物,在表达 ERα的乳腺癌细胞中发挥抗雌激素作用。它以浓度依赖的方式抑制 hERG, IC50值为1.6μM。
T1869 PluriSIn 1

4-吡啶羧酸 2-苯基酰肼,NSC 14613,PluriSIn #1,PluriSln 1

Apoptosis; Dehydrogenase; Stearoyl-CoA Desaturase (SCD) Apoptosis; Metabolism
PluriSIn 1 (NSC 14613) 是一种酰基-辅酶 A 去饱和酶抑制剂,是一种多能细胞特异性的抑制剂。
T9208 1,3,6,8-Tetrahydroxynaphthalene

T4HN,1,3,6,8-THN,naphthalene-1,3,6,8-tetrol

Others Others
1,3,6,8-Tetrahydroxynaphthalene (T4HN) 是一种独特的对称聚酮起源化合物,是 DHN 黑色素不可缺少的前体。
T11265 Faropenem daloxate

法罗培南酯,Faropenem medoxil

Antibacterial; Antibiotic Microbiology/Virology
Faropenem daloxate (Faropenem medoxil) 是β-内酰胺类口服抗生素。
T9697 ASK1-IN-1

ASK Apoptosis
ASK1-IN-1 是一种凋亡信号调节激酶 1(SK1) 抑制剂,具有良好的效价 (细胞IC50=138 nM; BiochemicalIC50=21 nM)。ASK1-IN-1具有中枢神经系统渗透性。
T9462 2-Amino-6-cyclopropylamino-9H-purine

Others Others
2-Amino-6-cyclopropylamino-9H-purine 是阿巴卡韦(abacavir) 的关键中间体,以氰基乙酸乙酯为原料,经亚硝化、盐酸胍在 EtONa 存在下环合、还原得到2,4,5-三氨基-6-羟基嘧啶
T21249L Myristoyl Pentapeptide-17 Acetate

Myristoyl Pentapeptide-17 Acetate(959610-30-1 Free base)

Others Others
Myristoyl Pentapeptide-17 Acetate 是一种小肽。促进关键成分的输送,从而有效促进睫毛生长,使睫毛变长变浓密,强韧秀发,显着强化眼部表情。
T4414 Eprenetapopt

APR-246,PRIMA-1Met

Apoptosis; Others; Ferroptosis; p53; Autophagy Apoptosis; Autophagy; Others
Eprenetapopt (PRIMA-1Met) 是一种在 TP53突变细胞中恢复野生型 p53功能的小分子,可引发肿瘤细胞凋亡,还抑制硒蛋白硫氧还蛋白还原酶 1。
TP2358 KRPEP-2D acetate

Raf MAPK
KRPEP-2D acetate 被鉴定为针对 K-Ras 的 G12D 突变体的 K-Ras(G12D) 选择性抑制肽,K-Ras 是 Ras 蛋白家族的关键成员和有吸引力的癌症治疗靶点。
T1497 Liranaftate

Piritetrate,利拉萘酯,M-732

Antifungal Microbiology/Virology
Liranaftate (Piritetrate) 是一种具有抗真菌活性的硫代氨基甲酸酯和角鲨烯环氧酶抑制剂,可研究皮肤癣菌。
T50030 1-(2,4-difluorophenyl)guanidine hydrochloride

Others Others
1-(2,4-difluorophenyl)guanidine hydrochloride 是一种化合物,是电压门控钠通道Nav1.7的强效选择性抑制剂,Nav1.7是疼痛信号传输的关键参与者,因此它能够减少疼痛信号的传递,从而产生镇痛作用。
TP2137L pp60 c-src (521-533) (phosphorylated) acetate

Others Others
pp60 c-src (521-533) (phosphorylated) acetate 是粘着斑形成和细胞扩散的调节剂。它还调节细胞运动,是由促运动透明质酸受体 RHAMM 触发的信号通路中的关键成分。
TP1820L Osteogenic Growth Peptide, OGP acetate

Osteogenic Growth Peptide, OGP acetate(132996-61-3 free base)

Others Others
Osteogenic Growth Peptide, OGP acetate(132996-61-3 free base) 是一种短的、天然存在的 14 聚体生长因子肽,存在于血清中,浓度为 μM。成骨生长肽 OGP 是局部骨髓损伤全身成骨反应机制的关键因素。
TP1359L Amyloid β Peptide (42-1)(human) acetate

Amyloid β Peptide (42-1)(human) acetate(317366-82-8 free base)

Beta Amyloid Neuroscience
Amyloid β Peptide (42-1)(human) acetate 是淀粉样蛋白 β 肽 (1-42) 的无活性形式。Amyloid β Peptide (42-1)(human) acetate 是由 42 个氨基酸组成的肽,其在阿尔茨海默病的发病机制中起关键作用。
T3520 Setipiprant

KYTH-105,塞替匹仑,ACT-129968

GPR; Prostaglandin Receptor Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation
Setipiprant (ACT-129968) 是一种口服的选择性 CRTH2 拮抗剂,IC50为6.0 nM。
T77597 SXC 2023

(S)-2-acetamido-3-(4-methylbenzoylthio)propanoic acid

Others Others
SXC 2023 ((S)-2-acetamido-3-(4-methylbenzoylthio)propanoic acid) 是一种可治疗中枢神经疾病和神经认知障碍的N-乙酰-L-半胱氨酸的前药,可用于治疗谷氨酸能功能障碍和氧化应激起关键作用的精神疾病。
T67729 UCM-1306

Dopamine Receptor GPCR/G Protein; Neuroscience
UCM-1306 是具有口服活性的人多巴胺 D1 受体变构调节剂 (PAM)。UCM-1306 增加结合在人和小鼠 D1 受体的内源性多巴胺 (DA) 效应。UCM-1306可以改善运动症状,解决与长期帕金森病(PD) 相关的关键共病认知障碍。
T21872 CCT018159

Apoptosis; HSP Apoptosis; Cytoskeletal Signaling; Metabolism
CCT018159 是一种 3,4-二芳基吡唑间苯二酚,是一种 ATP 竞争性HSP90ATPase 抑制剂,对人 Hsp90β 和酵母 Hsp90 具有抑制作用,IC50分别为 3.2 和 6.6 μM。CCT018159 抑制与侵袭和血管生成有关的关键内皮细胞和肿瘤细胞功能。CCT018159 引起与 G1 期阻滞相关的细胞抑制并诱导细胞凋亡。
T4473 Ibiglustat

Venglustat,SAR402671,GZ402671

Transferase Metabolism
Ibiglustat (GZ402671) 是一种可透过血脑屏障的、具有口服活性的葡萄糖神经酰胺合成酶(GCS)抑制剂。它可用于戈谢病 3 型、法布瑞氏症、与 GBA 突变相关的帕金森病、GM2 神经节苷脂病和常染色体显性多囊肾病的研究。
T1185 Rofecoxib

MK 966,罗非昔布,罗非考昔,MK-0966

COX Immunology/Inflammation; Neuroscience
Rofecoxib (MK 966) 是可口服的 COX-2特异性抑制剂,具有抗炎、解热和镇痛特性以及潜在的抗肿瘤特性。在人骨肉瘤细胞和中国仓鼠卵巢细胞中,对人 COX-2 的 IC50值分别为 26 和 18 nM。
T39584 MI-3454

Histone Methyltransferase Chromatin/Epigenetic
MI-3454 是一种具有口服活性,选择性和高效性的 Menin-MLL1 相互作用抑制剂,可抑制具有 MLL1 易位或 NPM1 突变的急性白血病细胞增殖并诱导分化。MI-3454 通过下调参与白血病发生的关键基因,诱导MLL1重排或NPM1突变白血病小鼠模型中白血病的完全缓解或消退。
T3716 Rolapitant

罗拉吡坦,SCH619734,罗拉匹坦

Neurokinin receptor GPCR/G Protein; Neuroscience
Rolapitant (SCH619734) 是一种高效选择性具有口服活性的神经激肽 1 受体抑制剂,Ki 值为0.66 nM。
T71704 Navamepent

RX-10045

Others Others
Navamepent (RX-10045) 是 resolvin E1 (一种膳食-3多不饱和脂肪酸代谢物)的类似物,具有强大的抗炎活性,可减少角膜炎症、上皮损伤,加速角膜组织修复。Navamepent 可抑制角膜上皮细胞释放几种关键促炎介质。Navamepent 对干眼和杯状细胞损失非常有效,可加速泪液的产生。
T6509 Galeterone

VN-124-1,TOK-001,VN/124-1,VN 124

P450; Androgen Receptor Endocrinology/Hormones; Metabolism
Galeterone (VN 124) 是CYP17抑制剂,能够多功能的抗雄激素,在去势抵抗性前列腺癌中,其IC50值为 47 nM。
T9108 BI-0115

Lipoxygenase Metabolism
BI-0115 是LOX-1的选择性抑制剂,其IC50值为 5.4 µM,可以阻止细胞摄取氧化低密度脂蛋白。它通过形成同源二聚体配体结合域的二聚体来触发受体抑制。
T4260 Capmatinib 2HCl

INC-280 2HCl,INCB28060盐酸盐,INCB28060 2HCl

c-Met/HGFR Tyrosine Kinase/Adaptors
Capmatinib 2HCl (INC-280 2HCl) 是一种新型的 ATP 竞争性 c-MET 激酶抑制剂,IC50 为 0.13 nM。它具有皮摩尔酶效,对 c-MET 具有高度特异性,选择性超过 10, 000 倍一大组人类激酶。该抑制剂在 c-MET 依赖性肿瘤细胞系中有效阻断 c-MET 磷酸化和其关键下游效应子的激活。因此,它在体外有效抑制 c-MET 依赖性肿瘤细胞增殖和迁移,并有效诱导细胞凋亡。
T3024 Avitinib

AC0010,艾维替尼

EGFR; JAK; BTK Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
Avitinib (AC0010) 是一种不可逆的、突变体选择性的EGFR 抑制剂,可有效抑制非小细胞肺癌中EGFR T790M 耐药突变。阿比替尼也是一种新型BTK 抑制剂。
T35610 2,5-dimethyl Celecoxib

Apoptosis; Wnt/beta-catenin; Prostaglandin Receptor Apoptosis; Cytoskeletal Signaling; GPCR/G Protein; Immunology/Inflammation; Stem Cells
2,5-dimethyl Celecoxib 是塞来昔布衍生物和微粒体前列腺素 E 合酶 1 (mPGES-1) 的靶向抑制剂,mPGES-1 是炎症介质 PGE2 合成途径中的关键酶。
T3226 Paritaprevir free base

ABT-450,Veruprevir,帕利瑞韦

HCV Protease Microbiology/Virology; Proteases/Proteasome
Paritaprevir free base (ABT-450) 是一种口服生物可利用的合成酰基磺酰胺抑制剂,可抑制丙型肝炎病毒 (HCV) 蛋白酶复合物,由非结构蛋白 3 和 4A (NS3/NS4A) 组成,对 HCV 基因型 1 具有潜在活性。 给药后,paritaprevir 可逆地结合 HCV NS3/NS4A 蛋白酶的活性中心和结合位点,并阻止 NS3/NS4A 蛋白酶介导的多蛋白成熟。这会破坏病毒蛋白的加工和病毒复制复合物的形成,从而抑制病毒在 HCV 基因型 1 感染的宿主细胞中的复制。 NS3 是一种丝氨酸蛋白酶,对于 HCV 多蛋白内多个位点的蛋白水解切割至关重要,并且在 HCV 核糖核酸 (RNA) 复制过程中起关键作用。 NS4A 是 NS3 的激活因子。 HCV 是属于黄病毒科的一种小的、有包膜的单链 RNA 病毒,感染与肝细胞癌 (HCC) 的发展有关。
T30806 CFLZ-567

Others Others
CFLZ-567 is a key intermediate for making carfilzomib.
T12557 PROTAC BET-binding moiety 1

Others Others
PROTAC BET-binding moiety 1 is a key intermediate in the synthesis of high affinity BET inhibitors
T21342 CFLZ-171 TFA salt

Others Others
CFLZ-171 is a key intermediate for the synthesis of carfilzomib.
T28211 NSC-668036

Others Others
NSC-668036 is an inhibitor of Dishevelled (Dvl) protein, a key protein in wnt signaling.
T28288 Pacidamycin I

A-68567,A 68567,A68567

Others Others
Pacidamycin I is an antimicrobial nucleoside antibiotics. Pacidamycin I inhibits translocase I, a key enzyme in peptidoglycan assembly.
T16843 Saridegib

IPI-926,Patidegib

Others Others
Saridegib is an effective and specific inhibitor of Smoothened and a key signaling transmembrane protein in the Hedgehog pathway.

化合物

Dexamethasone acetate
Cat.No: T0947
Synonym: Dexamethasone 21-acetate,醋酸地塞米松,Dexamethason acetate,NSC 39471
Target: Glucocorticoid Receptor, Mitophagy, IL Receptor, Annexin A, NOS, Antibacterial, Autophagy, ADC Cytotoxin
Parkeyl acetate
Cat.No: T33885
Synonym:
Target: Others
Cyclic MKEY
Cat.No: TP1620
Synonym:
Target:
Cyclic MKEY TFA
Cat.No: T78011
Synonym:
Target:
HS220
Cat.No: T60011
Synonym:
Target: MAPK
TP748
Cat.No: T19588
Synonym: 2-苄氧基恶唑
Target: Others
Benzylideneaniline
Cat.No: T20318
Synonym: N-苄叉苯胺,N-Benzylideneaniline
Target: Others
ELN484228
Cat.No: T4659
Synonym:
Target: Others
DLinDMA
Cat.No: T15140
Synonym:
Target: Others
Gonadorelin Acetate (33515-09-2 free base)
Cat.No: T5015
Synonym: 醋酸戈那瑞林,Luteinizing Hormone Releasing Hormone (LH-RH),Luteinizing Hormone Releasing Hormone (LH-RH), human,Gonadorelin Acetate
Target: Reductase
2-Acetyl-6-methoxynaphthalene
Cat.No: T0637
Synonym:
Target: Others
Shepherdin 79-87 acetate
Cat.No: T12896L
Synonym: Shepherdin 79-87 acetate (861224-28-4 free base)
Target: HSP, Survivin
Nelociguat
Cat.No: T7201
Synonym: N-[4,6-二氨基-2-[1-[(2-氟苯基)甲基]-1H-吡唑并[3,4-B]吡啶-3-基]-5-嘧啶]-氨基甲酸甲酯,BAY60-4552
Target: Guanylate cyclase
CRAC intermediate 1
Cat.No: T10884
Synonym: 5-(S)-Fluorowillardiine
Target: Calcium Channel
Aleplasinin
Cat.No: T29856
Synonym: PAZ 417,PAZ417,PAZ-417
Target: PAI-1
Endoxifen (Z-isomer)
Cat.No: T2280
Synonym: Z-因多昔芬,Endoxifen Z-isomer,4-[(1E)-1-{4-[2-(甲基氨基)乙氧基]苯基}-2-苯基-1-丁烯-1-基]苯酚
Target: Estrogen Receptor/ERR, EGFR, Potassium Channel, Estrogen/progestogen Receptor, HER
PluriSIn 1
Cat.No: T1869
Synonym: 4-吡啶羧酸 2-苯基酰肼,NSC 14613,PluriSIn #1,PluriSln 1
Target: Apoptosis, Dehydrogenase, Stearoyl-CoA Desaturase (SCD)
1,3,6,8-Tetrahydroxynaphthalene
Cat.No: T9208
Synonym: T4HN,1,3,6,8-THN,naphthalene-1,3,6,8-tetrol
Target: Others
Faropenem daloxate
Cat.No: T11265
Synonym: 法罗培南酯,Faropenem medoxil
Target: Antibacterial, Antibiotic
ASK1-IN-1
Cat.No: T9697
Synonym:
Target: ASK
2-Amino-6-cyclopropylamino-9H-purine
Cat.No: T9462
Synonym:
Target: Others
Myristoyl Pentapeptide-17 Acetate
Cat.No: T21249L
Synonym: Myristoyl Pentapeptide-17 Acetate(959610-30-1 Free base)
Target: Others
Eprenetapopt
Cat.No: T4414
Synonym: APR-246,PRIMA-1Met
Target: Apoptosis, Others, Ferroptosis, p53, Autophagy
KRPEP-2D acetate
Cat.No: TP2358
Synonym:
Target: Raf
Liranaftate
Cat.No: T1497
Synonym: Piritetrate,利拉萘酯,M-732
Target: Antifungal
1-(2,4-difluorophenyl)guanidine hydrochloride
Cat.No: T50030
Synonym:
Target: Others
pp60 c-src (521-533) (phosphorylated) acetate
Cat.No: TP2137L
Synonym:
Target: Others
Osteogenic Growth Peptide, OGP acetate
Cat.No: TP1820L
Synonym: Osteogenic Growth Peptide, OGP acetate(132996-61-3 free base)
Target: Others
Amyloid β Peptide (42-1)(human) acetate
Cat.No: TP1359L
Synonym: Amyloid β Peptide (42-1)(human) acetate(317366-82-8 free base)
Target: Beta Amyloid
Setipiprant
Cat.No: T3520
Synonym: KYTH-105,塞替匹仑,ACT-129968
Target: GPR, Prostaglandin Receptor
SXC 2023
Cat.No: T77597
Synonym: (S)-2-acetamido-3-(4-methylbenzoylthio)propanoic acid
Target: Others
UCM-1306
Cat.No: T67729
Synonym:
Target: Dopamine Receptor
CCT018159
Cat.No: T21872
Synonym:
Target: Apoptosis, HSP
Ibiglustat
Cat.No: T4473
Synonym: Venglustat,SAR402671,GZ402671
Target: Transferase
Rofecoxib
Cat.No: T1185
Synonym: MK 966,罗非昔布,罗非考昔,MK-0966
Target: COX
MI-3454
Cat.No: T39584
Synonym:
Target: Histone Methyltransferase
Rolapitant
Cat.No: T3716
Synonym: 罗拉吡坦,SCH619734,罗拉匹坦
Target: Neurokinin receptor
Navamepent
Cat.No: T71704
Synonym: RX-10045
Target: Others
Galeterone
Cat.No: T6509
Synonym: VN-124-1,TOK-001,VN/124-1,VN 124
Target: P450, Androgen Receptor
BI-0115
Cat.No: T9108
Synonym:
Target: Lipoxygenase
Capmatinib 2HCl
Cat.No: T4260
Synonym: INC-280 2HCl,INCB28060盐酸盐,INCB28060 2HCl
Target: c-Met/HGFR
Avitinib
Cat.No: T3024
Synonym: AC0010,艾维替尼
Target: EGFR, JAK, BTK
2,5-dimethyl Celecoxib
Cat.No: T35610
Synonym:
Target: Apoptosis, Wnt/beta-catenin, Prostaglandin Receptor
Paritaprevir free base
Cat.No: T3226
Synonym: ABT-450,Veruprevir,帕利瑞韦
Target: HCV Protease
CFLZ-567
Cat.No: T30806
Synonym:
Target: Others
PROTAC BET-binding moiety 1
Cat.No: T12557
Synonym:
Target: Others
CFLZ-171 TFA salt
Cat.No: T21342
Synonym:
Target: Others
NSC-668036
Cat.No: T28211
Synonym:
Target: Others
Pacidamycin I
Cat.No: T28288
Synonym: A-68567,A 68567,A68567
Target: Others
Saridegib
Cat.No: T16843
Synonym: IPI-926,Patidegib
Target: Others
Cat. No. Product Name Target Signaling Pathways
TN1243 3-Aminocoumarin

3-Amino-2-benzopyrone,3-aminochromen-2-one,Coumarin amine

Others Others
3-Aminocoumarin (3-aminochromen-2-one) 是金属配合物的关键中间体。
T5804 Pneumocandin B0

纽莫康定B0,L-688786

Antibiotic; Antifungal Microbiology/Virology
Pneumocandin B0 (L-688786)是 Cancidas 的合成中间体。
T7479 Ambroxide

降龙涎香醚,(-)-Ambroxide

Others Others
Ambroxide ((-)-Ambroxide) 是龙涎香的一种关键成分,是天然存在的萜类化合物。
T20255 L-Galactose

Galactose, L-

Endogenous Metabolite Metabolism
L-Galactose (Galactose, L-) 是一种天然产物,广泛存在动植物体内。L-Galactose 在Pistia stratiotes 中被证明是D-葡萄糖转化为草酸的分子途径中的关键中间体。
T22300 Creatine monohydrate

Methylguanidoacetic acid monohydrate,一水肌酸

Others; Endogenous Metabolite Metabolism; Others
Creatine monohydrate (Methylguanidoacetic acid monohydrate) 是磷酸原能量系统的关键参与者,尤其是在肌肉和大脑中。 Creatine monohydrate 是高强度、短期活动中 ATP 的主要来源。
T4921 Oxoadipic acid

2-氧代己二酸,2-Oxoadipic acid

Endogenous Metabolite Metabolism
Oxoadipic acid (2-Oxoadipic acid) 是必需氨基酸色氨酸和赖氨酸的一种代谢物。
TN3689 Comanthoside A

Comanthosid A

Others Others
Comanthoside A (Comanthosid A) 是一种可从 Comanthosphace japonica 中分离的天然黄酮苷。Comanthoside A 也 是合成 Linaroside和 Comanthoside B 的关键中间体。
T6S0655 Corynoxeine

ERK MAPK
Corynoxeine 是从钩藤中分离的一种天然产物,是 PDGF-BB 诱导血管平滑肌细胞 (VSMCs) 增殖过程中的 ERK1/ERK2抑制剂。
T10939L L-Cystathionine

L-胱硫醚,Cystathionine,ZINC1532680,L-(+)-Cystathionine,Cystathionine, L-

Apoptosis; Endogenous Metabolite Apoptosis; Metabolism
L-Cystathionine (Cystathionine, L-) 是一种与含硫氨基酸的代谢条件有关的关键非蛋白质氨基酸。L-Cystathionine 可用于有关心血管保护的研究。
T5980 2-Ketoglutaric acid

α-酮戊二酸,alpha-酮戊二酸

Tyrosinase; Endogenous Metabolite Metabolism; Proteases/Proteasome
2-Ketoglutaric acid 是 Krebs 循环的中间体,可以产生 ATP 或 GTP 。2-Ketoglutaric acid 还充当氮同化反应的主要碳骨架。2-Ketoglutaric acid 是酪氨酸酶(tyrosinase)的可逆抑制剂 (IC50=15 mM)。
T5770 Alisol B

RANKL/RANK NF-κB
Alisol B 是一种具有用于骨科疾病研究潜力的化合物,通过分化破骨细胞发挥其功能。
T13502 3-Oxo-5β-cholanoic acid

3-氧代-5β-胆烷酸,Dehydrolithocholic acid

ROR Metabolism
3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid) 是胆汁酸的一种代谢产物。3-Oxo-5β-cholanoic acid 直接与关键转录因子RORγt(Kd=1.13 μM) 结合抑制TH17细胞分化。
T2O2701 L-Ornithine hydrochloride

L(+)-Ornithine hydrochloride,(S)-2,5-Diaminopentanoic acid,L-鸟氨酸盐酸盐;L-2,5-二氨基戊酸盐酸盐;L-鸟氨酸单盐酸盐;鸟氨酸盐酸盐;L-盐酸鸟氨酸;L-鸟粪氨基酸盐酸盐

Others; Endogenous Metabolite Metabolism; Others
L-Ornithine hydrochloride ((S)-2,5-Diaminopentanoic acid) 通过提高能量消耗效率和促进氨的排泄而具有抗疲劳作用。它是尿素循环中的关键反应物之一。
T22446 NADP disodium salt

Disodium NADP,Triphosphopyridine nucleotide disodium salt,beta-烟酰胺腺嘌呤二核苷酸磷酸二钠盐

Others Others
NADP disodium salt (Disodium NADP) 是一种氧化还原辅助因子,是一种烟酰胺腺嘌呤二核苷酸。它是代谢中电子转移的关键辅因子,可以被交替氧化 (NADP+) 和还原 (NADPH)。
T21437 DSPS

DSPS (From soybeans),Phosphatidylserine(36:0),磷脂酰丝氨酸,Dioctadecanoylphosphatidylserine,Distearoyl phosphatidylserine

Others Others
DSPS (Dioctadecanoylphosphatidylserine) 是一种甘油磷脂,是重要的磷脂膜成分,在细胞周期信号传导中起关键作用。DSPS 可以调节细胞活性,介导细胞凋亡。DSPS 被广泛用作营养补充剂。
T5249 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine

1,2-DSPE,1,2-二硬酯酰-SN-甘油-3-磷酰乙醇胺,1,2-Distearoyl-sn-glycero-3-phosphoethan

Others; Endogenous Metabolite Metabolism; Others
1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (1,2-DSPE) 是一种磷脂酸乙醇胺 (PE) ,能够用于合成脂质体。
T4928 L-Kynurenine

L-犬尿氨酸,(S)-Kynurenine

AhR; Aryl Hydrocarbon Receptor; Endogenous Metabolite Immunology/Inflammation; Metabolism
L-Kynurenine ((S)-Kynurenine) 是L-色氨酸的代谢物,是芳香烃受体激动剂,可抑制同种异体 T 细胞增殖并增加恶性 U87 神经胶质瘤细胞侵入胶原基质。
T2133 Adenosine monophosphate

5'-Adenylic acid,5'-腺嘌呤核苷酸,AMP,Adenosine 5'-monophosphate

Endogenous Metabolite; AMPK Chromatin/Epigenetic; Metabolism; PI3K/Akt/mTOR signaling
Adenosine monophosphate (AMP) 是一种嘌呤核糖核苷5'-单磷酸腺苷,是信号转导和调节能量稳态的关键细胞代谢物。它具有EC 3.1.3.11(果糖-二磷酸酶)抑制剂、EC 3.1.3.1(碱性磷酸酶)抑制剂和腺苷A1受体激动剂的作用。
T4920 2-Ketoglutaric acid Sodium

Oxoglutaric acid,AKG,2-oxoglutarate monobasic,LPHA-酮戊二酸钠,α-Ketoglutaric acid sodium salt

Tyrosinase; Endogenous Metabolite Metabolism; Proteases/Proteasome
2-Ketoglutaric acid Sodium (AKG) 是一种三羧酸循环的中间产物,它可以由谷氨酸通过谷氨酸脱氢酶氧化脱氨产生,也可以作为磷酸吡哆醛依赖的转氨化反应的产物(由支链氨基酸转氨酶介导),其中谷氨酸是常见的氨基供体。
T5079 Adenosine 5'-diphosphate sodium salt

腺苷-5‘-二磷酸钠盐,Adenosine-5'-diphosphate trisodium salt,ADP sodium salt

Others; Endogenous Metabolite Metabolism; Others
Adenosine 5'-diphosphate sodium salt (ADP sodium salt) 是一种核苷二磷酸,是一种 ATP 酶对 ATP 去磷酸化的产物。它通过在 P2T-嘌呤受体上的作用诱导人血小板聚集并抑制刺激的腺苷酸环化酶。
T5243 (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate

DMPE,1,2-十四酰基磷脂酰乙醇胺,1,2-Dihexadecanoyl-sn-glycero-3-phosphoethanolamine,1,2-Dimyristoyl-sn-glycero-3-PE

Others; Endogenous Metabolite Metabolism; Others
(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate (DMPE) 是内源性代谢产物的一种。
TN6508 Trachelogenin

(-)-Trachelogenin

Virus Protease; c-Myc; HCV Protease; Wnt/beta-catenin Cell Cycle/Checkpoint; Cytoskeletal Signaling; Microbiology/Virology; Proteases/Proteasome; Stem Cells
Trachelogenin ((-)-Trachelogenin) 分离自Combretum fruticosum,是一种 HCV 进入抑制剂 具有抗增殖作用,其机制与影响β-Catenin 信号通路中的 β-Catenin、c-Myc 和 GSK3 等关键蛋白的磷酸化有关,且呈浓度依赖性。Trachelogenin具有抗病毒、抗炎和镇痛活性,在 HCVcc 和 HCVpp 模型中的 IC50 分别为 0.325 和 0.259 μg/mL。
T4889 2,6-Diaminoheptanedioic acid

Others; Endogenous Metabolite Metabolism; Others
2,6-Diaminoheptanedioic acid 是内源性代谢产物的一种。
T6S1572 Sauchinone

ERK; p38 MAPK; NF-κB MAPK; NF-κB
Sauchinone 是一种从Saururus chinensis 中获得的非对映异构的木脂素。它通过抑制I-κBα磷酸化和p65核易位来抑制 LPS 诱导的 iNOS,TNF-α 和 COX-2 表达。它具有抗炎和抗氧化活性。
T2966 Beta-Sitosterol

Cupreol,谷甾醇,Beta-Sitosterol,β-Sitosterol,Azuprostat,SKF 14463,beta-谷甾醇,22,23-Dihydrostigmasterol,Betaprost

Apoptosis; Lipase; Endogenous Metabolite Apoptosis; Metabolism
Beta-Sitosterol (SKF 14463) 属于天然产物,是一种植物甾醇,广泛存在于植物界。Beta-Sitosterol 的摄人量与许多慢性病的发生率有关系,比如具有明显降低血清胆固醇的功效。
T6S1315 Oroxylin A

千层纸素A,6-Methoxybaicalein,Baicalein 6-methyl ether

Virus Protease; HIF/HIF Prolyl-Hydroxylase; Autophagy Autophagy; Chromatin/Epigenetic; Metabolism; Microbiology/Virology
Oroxylin A (Baicalein 6-methyl ether) 是一种有活性的黄酮,具有较强的抗癌作用。
T4838 (S)-Malic acid

L-(-)-Malic acid,(S)-(-)-HYDROXYSUCCINIC ACID,(S)-2-Hydroxysuccinic acid,L-苹果酸

Others; Endogenous Metabolite Metabolism; Others
(S)-Malic acid ((S)-2-Hydroxysuccinic acid) 是天然存在的二羧酸,是水果酸甜味的来源,常用作食品添加剂。
T13732 Hydroxy-Epsilon-Sanshool

Others Others
Hydroxy-Epsilon-Sanshool is an alkyl amide isolated from Zanthoxylum bungeanum. Hydroxy-Epsilon-Sanshool produces key tingling and numbing chemosensation.
T20447 L-Linalool

p-Linalool

L-Linalool is the jasmine tea, spruce essential oil, and young leaves of Litchi chinensis Sonn key volatile compound.
T40758 Hydrastinine

Others Others
Hydrastinine, a key alkaloid component found in Hydrastis canadensis (goldenseal), serves as an effective hemostatic agent.
T10025 1-PeCSO

S-1-Propenyl-L-cysteine sulfoxide

Others Others
1-PeCSO is isolated from onion or garlic bulbs. It acts as a key compound in garlic greening and reacts with lachrymatory factor synthase.
T10074 2-Keto-D-Glucose

D-Glucosone

Others Others
2-Keto-D-Glucose (D-Glucosone) is a key intermediate in a secondary metabolic pathway leading to the antibiotic Cortalcerone. It is found in various natural sources, including fungi, algae, and shellfish.
TN4473 Macrocarpal A

Antifection Microbiology/Virology
Macrocarpal A is the key component that stimulates the synthesis of ceramide in the stratum corneum. Macrocarpal A has cytotoxic, and antibacterial activities.
T20628 Kifunensine

Kifunensine, a potent and selective inhibitor of class I α-mannosidases, may serve as a key inhibitor of glycoprotein biosynthesis. Its inhibitory effect may lead to high mannose glycoproteins in cell culture.
T40458 3-Keto petromyzonol

Others Others
3-Keto petromyzonol, a key constituent of Sea lamprey male sex pheromones, governs the synthesis and release of gonadotropin releasing hormone (GnRH). This in turn regulates the hypothalamic-pituitary-gonadal (HPG) output in immature sea lamprey.
T80953 Tremulacin

Tremulacin为Populus树皮及其叶子中的关键糖苷组分。
TN1952 Moracin P

桑辛素 P,桑辛素P

Others; ROS; HIF Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; Others
Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia.
TN4016 Ethyl 2,4,6-trihydroxybenzoate

Liver X Receptor Metabolism
Ethyl 2,4,6-trihydroxybenzoate is a dual-LXR modulator that regulates the expression of key genes in cholesterol homeostasis in multiple cells without inducing lipid accumulation in HepG2 cells. It suppresses cellular cholesterol accumulation in a dose-dependent manner and induces the transcriptional activation of LXR-α/-β-responsive genes.
T10194 7-Methylguanine

Others Others
7-Methylguanine is a metabolite of DNA methylation. It can be generated by methylating agents and used as a probe of DNA–protein interactions and a key component of the DNA sequencing method.
T10910 Cycloartenol

Others Others
Cyclopentanol is a plant sterol compound and one of the key precursors for biosynthesis of various sterol compounds. Cycloartenol inhibits the migration of glioma cells and inhibits the phosphorylation of p38 MAP kinase. Cycloenol has various pharmacologi
TN3725 Cucurbitadienol

Cucurbitadienol has significant anti-inflammatory, anti-tumor effect, is also CucurbitacinBE compounds biosynthesis the key intermediate. Cucurbitadienol synthase, the first committed enzyme for cucurbitacin biosynthesis, is a distinct enzyme from cycloar
TN1783 Isolicoflavonol

异甘草黄酮醇

Lipid Metabolism
Isolicoflavonol 以可逆和混合的方式抑制人羧酸酯酶2介导的荧光素二乙酸酯水解, Ki 小于1.0 μM。
T83902 Polymyxin E1 sulfate

Colistin A sulfate

Others Others
Polymyxin E1,是一种肽类抗生素,也是原初从B. polymyxa分离得到的阳离子脂肽抗生素colistin的主要成分。对P. aeruginosa和E. coli具有活性(MICs分别为2和0.8 µg/ml)。
TN6198 Mahanine

Mahanine has effects on the activation of the apoptotic pathway in human leukemia U937 cells, causes the mitochondrial membranes to lose their permeability, resulting in caspase-3 activation and apoptosis. Mahanine can reverse an epigenetically silenced g
TN1951 Moracin O

桑辛素 O,桑辛素O

HIF Angiogenesis; Chromatin/Epigenetic
Moracin O shows significant neuroprotective, and analgesic activities, it also has a strong protective influence against doxorubicin-induced cardiomyopathy in H9c2 cells with the EC50 value of 4.5 ± 1.3 μM. Moracin O exhibits potent in vitro inhibitory ac
T74368 OKI-006

Others Others
OKI-006 是一种有效的、具有口服活性的组蛋白脱乙酰酶 (HDAC) 抑制剂。OKI-006 是天然产物HDAC 抑制剂 largazole 的独特同系物。组蛋白去乙酰化酶 (HDAC) 在表观基因组调控中起关键作用,并且组蛋白乙酰化在许多人类癌症中失调。OKI-006 具有研究癌症疾病的潜力。
T83904 Polymyxin E2 sulfate

Colistin B sulfate

Others Others
Polymyxin E2 是一种肽类抗生素,也是最初从B. polymyxa分离出的阳离子脂肽抗生素colistin的主要成分。该化合物对植物致病菌X. oryzae具有活性(EC50 = 0.21 µg/ml),并且在温室研究中,当以200 µg/ml的浓度应用时,能够预防和逆转水稻细菌性叶枯病。
T82822 Brassicanate A sulfoxide

Brassicanate A sulfoxide 表现出除草效果,它能抑制植物中必需氨基酸的生物合成路径。该化合物通过结合并抑制多种酶的活性来发挥其作用,包括二羟酸脱水酶 (DHAD)、羟甲基丙酮酸双加氧酶 (HPPD)、乙酰乳酸合酶 (ALS)、PYL家族蛋白及转运抑制剂响应 1 (TIR1)。Brassicanate A sulfoxide 可以从甘蓝 (Brassica oleracea) 中提取获得。
T72581 SARS-CoV MPro-IN-2

Others Others
SARS-CoVMPro-IN-2 是一种有效的SARS-CoV-2 Mpro 抑制剂,IC50sub>值为 72.07 nM。病毒的主要蛋白酶 Mpro 作为加工病毒多蛋白的主要酶,有助于 SARS-CoV-2 在宿主细胞中的复制和转录,并已被定性为药物发现的有吸引力的靶点。SARS-CoVMPro-IN-2 具有研究 COVID-19 的潜力。
TN3364 Agrimonolide

Apoptosis; Dehydrogenase; p38 MAPK; ROS; JAK Angiogenesis; Apoptosis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; MAPK; Metabolism; Stem Cells
Agrimonolide 是一种来自异香豆素的化合物,主要存在于草药Agrimonia pilosa Ledeb 中,具有显著的生物活性。Agrimonolide 通过抑制脂多糖(LPS)诱导的JAK-STATs 和p38 MAPKs 信号通路的激活而发挥抗炎作用。Agrimonolide 及其衍生物去甲阿戈莫内德已显示出能够有效提高肝细胞中胰岛素介导的糖原水平,可能在调节胰岛素抵抗的HepG2细胞中发挥关键作用。Agrimonolide 通过靶向卵巢癌细胞中的SCD1,对癌症的进展和诱导细胞死亡和凋亡表现出抑制作用。特别是,Agrimonolide 对A2780和SKOV-3细胞的增殖、迁移和侵袭表现出剂量依赖性的抑制,同时促进细胞凋亡。该化合物还被发现能诱导铁介导的细胞死亡,同时增加活性氧(ROS)和总铁的水平。Agrimonolide 很容易穿过血脑屏障,表明其在神经系统疾病的治疗应用方面具有潜力。
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天然产物

3-Aminocoumarin
Cat.No: TN1243
Synonym: 3-Amino-2-benzopyrone,3-aminochromen-2-one,Coumarin amine
Target: Others
Pneumocandin B0
Cat.No: T5804
Synonym: 纽莫康定B0,L-688786
Target: Antibiotic, Antifungal
Ambroxide
Cat.No: T7479
Synonym: 降龙涎香醚,(-)-Ambroxide
Target: Others
L-Galactose
Cat.No: T20255
Synonym: Galactose, L-
Target: Endogenous Metabolite
Creatine monohydrate
Cat.No: T22300
Synonym: Methylguanidoacetic acid monohydrate,一水肌酸
Target: Others, Endogenous Metabolite
Oxoadipic acid
Cat.No: T4921
Synonym: 2-氧代己二酸,2-Oxoadipic acid
Target: Endogenous Metabolite
Comanthoside A
Cat.No: TN3689
Synonym: Comanthosid A
Target: Others
Corynoxeine
Cat.No: T6S0655
Synonym:
Target: ERK
L-Cystathionine
Cat.No: T10939L
Synonym: L-胱硫醚,Cystathionine,ZINC1532680,L-(+)-Cystathionine,Cystathionine, L-
Target: Apoptosis, Endogenous Metabolite
2-Ketoglutaric acid
Cat.No: T5980
Synonym: α-酮戊二酸,alpha-酮戊二酸
Target: Tyrosinase, Endogenous Metabolite
Alisol B
Cat.No: T5770
Synonym:
Target: RANKL/RANK
3-Oxo-5β-cholanoic acid
Cat.No: T13502
Synonym: 3-氧代-5β-胆烷酸,Dehydrolithocholic acid
Target: ROR
L-Ornithine hydrochloride
Cat.No: T2O2701
Synonym: L(+)-Ornithine hydrochloride,(S)-2,5-Diaminopentanoic acid,L-鸟氨酸盐酸盐;L-2,5-二氨基戊酸盐酸盐;L-鸟氨酸单盐酸盐;鸟氨酸盐酸盐;L-盐酸鸟氨酸;L-鸟粪氨基酸盐酸盐
Target: Others, Endogenous Metabolite
NADP disodium salt
Cat.No: T22446
Synonym: Disodium NADP,Triphosphopyridine nucleotide disodium salt,beta-烟酰胺腺嘌呤二核苷酸磷酸二钠盐
Target: Others
DSPS
Cat.No: T21437
Synonym: DSPS (From soybeans),Phosphatidylserine(36:0),磷脂酰丝氨酸,Dioctadecanoylphosphatidylserine,Distearoyl phosphatidylserine
Target: Others
1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine
Cat.No: T5249
Synonym: 1,2-DSPE,1,2-二硬酯酰-SN-甘油-3-磷酰乙醇胺,1,2-Distearoyl-sn-glycero-3-phosphoethan
Target: Others, Endogenous Metabolite
L-Kynurenine
Cat.No: T4928
Synonym: L-犬尿氨酸,(S)-Kynurenine
Target: AhR, Aryl Hydrocarbon Receptor, Endogenous Metabolite
Adenosine monophosphate
Cat.No: T2133
Synonym: 5'-Adenylic acid,5'-腺嘌呤核苷酸,AMP,Adenosine 5'-monophosphate
Target: Endogenous Metabolite, AMPK
2-Ketoglutaric acid Sodium
Cat.No: T4920
Synonym: Oxoglutaric acid,AKG,2-oxoglutarate monobasic,LPHA-酮戊二酸钠,α-Ketoglutaric acid sodium salt
Target: Tyrosinase, Endogenous Metabolite
Adenosine 5'-diphosphate sodium salt
Cat.No: T5079
Synonym: 腺苷-5‘-二磷酸钠盐,Adenosine-5'-diphosphate trisodium salt,ADP sodium salt
Target: Others, Endogenous Metabolite
(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate
Cat.No: T5243
Synonym: DMPE,1,2-十四酰基磷脂酰乙醇胺,1,2-Dihexadecanoyl-sn-glycero-3-phosphoethanolamine,1,2-Dimyristoyl-sn-glycero-3-PE
Target: Others, Endogenous Metabolite
Trachelogenin
Cat.No: TN6508
Synonym: (-)-Trachelogenin
Target: Virus Protease, c-Myc, HCV Protease, Wnt/beta-catenin
2,6-Diaminoheptanedioic acid
Cat.No: T4889
Synonym:
Target: Others, Endogenous Metabolite
Sauchinone
Cat.No: T6S1572
Synonym:
Target: ERK, p38 MAPK, NF-κB
Beta-Sitosterol
Cat.No: T2966
Synonym: Cupreol,谷甾醇,Beta-Sitosterol,β-Sitosterol,Azuprostat,SKF 14463,beta-谷甾醇,22,23-Dihydrostigmasterol,Betaprost
Target: Apoptosis, Lipase, Endogenous Metabolite
Oroxylin A
Cat.No: T6S1315
Synonym: 千层纸素A,6-Methoxybaicalein,Baicalein 6-methyl ether
Target: Virus Protease, HIF/HIF Prolyl-Hydroxylase, Autophagy
(S)-Malic acid
Cat.No: T4838
Synonym: L-(-)-Malic acid,(S)-(-)-HYDROXYSUCCINIC ACID,(S)-2-Hydroxysuccinic acid,L-苹果酸
Target: Others, Endogenous Metabolite
Hydroxy-Epsilon-Sanshool
Cat.No: T13732
Synonym:
Target: Others
L-Linalool
Cat.No: T20447
Synonym: p-Linalool
Target:
Hydrastinine
Cat.No: T40758
Synonym:
Target: Others
1-PeCSO
Cat.No: T10025
Synonym: S-1-Propenyl-L-cysteine sulfoxide
Target: Others
2-Keto-D-Glucose
Cat.No: T10074
Synonym: D-Glucosone
Target: Others
Macrocarpal A
Cat.No: TN4473
Synonym:
Target: Antifection
Kifunensine
Cat.No: T20628
Synonym:
Target:
3-Keto petromyzonol
Cat.No: T40458
Synonym:
Target: Others
Tremulacin
Cat.No: T80953
Synonym:
Target:
Moracin P
Cat.No: TN1952
Synonym: 桑辛素 P,桑辛素P
Target: Others, ROS, HIF
Ethyl 2,4,6-trihydroxybenzoate
Cat.No: TN4016
Synonym:
Target: Liver X Receptor
7-Methylguanine
Cat.No: T10194
Synonym:
Target: Others
Cycloartenol
Cat.No: T10910
Synonym:
Target: Others
Cucurbitadienol
Cat.No: TN3725
Synonym:
Target:
Isolicoflavonol
Cat.No: TN1783
Synonym: 异甘草黄酮醇
Target: Lipid
Polymyxin E1 sulfate
Cat.No: T83902
Synonym: Colistin A sulfate
Target: Others
Mahanine
Cat.No: TN6198
Synonym:
Target:
Moracin O
Cat.No: TN1951
Synonym: 桑辛素 O,桑辛素O
Target: HIF
OKI-006
Cat.No: T74368
Synonym:
Target: Others
Polymyxin E2 sulfate
Cat.No: T83904
Synonym: Colistin B sulfate
Target: Others
Brassicanate A sulfoxide
Cat.No: T82822
Synonym:
Target:
SARS-CoV MPro-IN-2
Cat.No: T72581
Synonym:
Target: Others
Agrimonolide
Cat.No: TN3364
Synonym:
Target: Apoptosis, Dehydrogenase, p38 MAPK, ROS, JAK
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Cat. No. Product Name Species Expression System
TMPH-01003 ATG14 Protein, Human, Recombinant (His & Myc)

Barkor,Autophagy-related protein 14-like protein,ATG14L,Becl...

Human E. coli
ATG14 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 60.3 kDa and the accession number is Q6ZNE5.
TMPY-06588 Monkeypox Virus (MPXV) A5L Protein (His)

MPXV E. coli
Monkeypox Virus (MPXV) A5L Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 31.95 kDa and the accession number is QNP13710.1.
TMPY-04738 Influenza A H5N8 (A/turkey/California/K1500169-1.2/2015) Hemagglutinin/HA1 Protein (His)

Harvey rat sarcoma viral oncogene homolog

H5N8 HEK293 Cells
Influenza A H5N8 (A/turkey/California/K1500169-1.2/2015) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.7 kDa and the accession number is A0A0F6T4B3.
TMPY-06569 Monkeypox Virus (MPXV) B6R Protein (His)

MPXV HEK293 Cells
Monkeypox Virus (MPXV) B6R Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.52 kDa and the accession number is QNP13760.1.
TMPY-06522 Monkeypox Virus (MPXV) Protein A29 (His)

MPXV E. coli
Monkeypox Virus (MPXV) Protein A29 (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 11.36 kDa and the accession number is QNP13733.1.
TMPY-06606 Monkeypox Virus (MPXV) B6R Protein (His), Biotinylated

MPXV HEK293 Cells
Monkeypox Virus (MPXV) B6R Protein (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.52 kDa and the accession number is QNP13760.1.
TMPY-04174 Influenza A H7N3 (A/turkey/Italy/214845/2002) Hemagglutinin/HA1 Protein (His)

Harvey rat sarcoma viral oncogene homolog

H7N3 HEK293 Cells
Influenza A H7N3 (A/turkey/Italy/214845/2002) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q701U0.
TMPY-00370 Influenza A H7N1 (A/turkey/Italy/4602/99) Hemagglutinin/HA1 Protein (His)

Harvey rat sarcoma viral oncogene homolog

H7N1 HEK293 Cells
Influenza A H7N1 (A/turkey/Italy/4602/99) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q7TAW6.
TMPY-06602 Monkeypox Virus (MPXV) C19L Protein (His)

MPXV Baculovirus Insect Cells
Monkeypox Virus (MPXV) C19L Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 43.25 kDa and the accession number is QNP13638.1.
TMPY-06523 Monkeypox Virus (MPXV) L1R Protein (His)

MPXV E. coli
Monkeypox Virus (MPXV) L1R Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 19.64 kDa.
TMPK-01253 A35R Protein, Monkeypox virus, Recombinant (His)

A35R

Monkeypox virus HEK293 Cells
Monkeypox virus (MPXV) is double-stranded DNA virus belonging to the genus orthopoxvirus that causes a smallpox-like disease in humans. A35R Protein, Monkeypox virus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 14.77 kDa and the accession number is QJQ40286.1.
TMPK-01123 A29 Protein, Monkeypox virus, Recombinant (His)

A29L,IMV surface,14 kDa protein,14kDa fusion

Monkeypox virus E. coli
Monkeypox virus (MPXV) is double-stranded DNA virus belonging to the genus orthopoxvirus that causes a smallpox-like disease in humans. A29 Protein, Monkeypox virus, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 13.65 kDa and the accession number is Q90188.
TMPY-04166 Influenza A H7N3 (A/turkey/Italy/214845/2002) Hemagglutinin/HA Protein (His)

Harvey rat sarcoma viral oncogene homolog

H7N3 Baculovirus Insect Cells
Influenza A H7N3 (A/turkey/Italy/214845/2002) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.8 kDa and the accession number is Q701U0.
TMPY-06562 Monkeypox Virus (MPXV) Envelope protein E8L Protein (His)

MPXV Baculovirus Insect Cells
Monkeypox Virus (MPXV) Envelope protein E8L Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 35.75 kDa and the accession number is QNP13700.1.
TMPY-06529 Monkeypox Virus (MPXV) Protein A35 (His)

MPXV HEK293 Cells
Monkeypox Virus (MPXV) Protein A35 (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.12 kDa.
TMPY-00421 Influenza A H5N8 (A/turkey/Ireland/1378/1983) Hemagglutinin/HA Protein (His)

Harvey rat sarcoma viral oncogene homolog

H5N8 Baculovirus Insect Cells
Influenza A H5N8 (A/turkey/Ireland/1378/1983) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.4 kDa and the accession number is P11135.
TMPY-04606 Influenza A H5N8 (A/turkey/Germany-MV/R2472/2014 ) Hemagglutinin/HA1 Protein (His)

Harvey rat sarcoma viral oncogene homolog

H5N8 HEK293 Cells
Influenza A H5N8 (A/turkey/Germany-MV/R2472/2014 ) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.8 kDa.
TMPY-06568 Monkeypox Virus (MPXV) M1R Protein (His)

MPXV HEK293 Cells
Monkeypox Virus (MPXV) M1R Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.59 kDa and the accession number is QNP13675.1.
TMPK-01116 A30 Protein, Monkeypox virus, Recombinant (His)

Envelope protein A28 homolog,A30,A30L,Protein A30

Monkeypox virus HEK293 Cells
Monkeypox virus (MPXV) is double-stranded DNA virus belonging to the genus orthopoxvirus that causes a smallpox-like disease in humans. A30L is an envelope protein required for the fusion of virus and host cell to form syncytia, and is also considered to be an important target in MPXV research.
TMPK-01252 E8L Protein, Monkeypox virus, Recombinant (His)

Cell surface-binding protein,Carbonic anhydrase homolog

Monkeypox virus E. coli
E8L is an important protein that mediates the invasion of monkeypox virus into host cells. In the process of invading and completing replication, E8L acts as a surface-binding protein of mature virion and can bind to chondroitin sulfate on the cell surface, so that the virus can attach to target cells.
TMPK-01250 M1R Protein, Monkeypox virus, Recombinant (His)

Monkeypox virus,M1R

Monkeypox virus HEK293 Cells
Monkeypox virus (MPXV) is double-stranded DNA virus belonging to the genus orthopoxvirus that causes a smallpox-like disease in humans. M1R Protein, Monkeypox virus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 20.41 kDa and the accession number is QJQ40223.1.
TMPK-01251 L1R Protein, Monkeypox virus, Recombinant (His)

0

Monkeypox virus E. coli
L1R, a myristylated late gene product of vaccinia virus, is essential for formation of infectious intracellular mature virions (IMV). In its absence, only viral particles arrested at an immature stage are detected and no infectious progeny virus is produced.
TMPY-06584 Monkeypox Virus (MPXV) A33R Protein (His & GST)

MPXV E. coli
Monkeypox Virus (MPXV) A33R Protein (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 44.07 kDa.
TMPY-06540 Monkeypox Virus (MPXV) Envelope protein H3 (His)

MPXV HEK293 Cells
Monkeypox Virus (MPXV) Envelope protein H3 (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.69 kDa and the accession number is QNP13688.1.
TMPY-06539 Monkeypox Virus (MPXV) I1L Protein (His)

MPXV E. coli
Monkeypox Virus (MPXV) I1L Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 37.71 kDa.
TMPY-00202 Influenza A H5N8 (A/turkey/Ireland/1378/1983) Hemagglutinin/HA1 Protein (His)

Harvey rat sarcoma viral oncogene homolog

H5N8 HEK293 Cells
Influenza A H5N8 (A/turkey/Ireland/1378/1983) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.8 kDa and the accession number is P11135.
TMPY-01128 Influenza A H5N1 (A/turkey/Turkey/1/2005) Hemagglutinin/HA Protein (His)

Harvey rat sarcoma viral oncogene homolog

H5N1 HEK293 Cells
Influenza A H5N1 (A/turkey/Turkey/1/2005) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is Q207Z6.
TMPY-04840 Influenza A H5N8 (A/turkey/Germany-MV/R2472/2014) Hemagglutinin/HA Protein (His)

Harvey rat sarcoma viral oncogene homolog

H5N8 Baculovirus Insect Cells
Influenza A H5N8 (A/turkey/Germany-MV/R2472/2014) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 60.1 kDa.
TMPH-02151 OXCT1 Protein, Human, Recombinant (His)

OXCT1,Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mito...

Human E. coli
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. OXCT1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 56.1 kDa and the accession number is P55809.
TMPY-02115 R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His)

CRISTIN1,THSD2,R-spondin 3,PWTSR

Human HEK293 Cells
R-spondin 3 (RSPO3) is a member of the R-Spondin (RSPO) family in vertebrates that activate Wnt/beta-catenin signaling, plays a key role in these processes. The RSPO family of secreted Wnt modulators is involved in development and disease and holds therapeutic promise as stem cell growth factors. The four members have high structural homology. RSPO2 and RSPO3 are more potent than RSPO1, whereas RSPO4 is relatively inactive. All RSPO members require Wnt ligands and LRP6 for activity and amplify s...
TMPK-00305 TGFBR1 Protein, Human, Recombinant (mFc & Avi)

tbetaR-I,TGFβRI,TGFbetaRI,LDS2A,ALK-5,TGF-beta RI,tβR-I,TGF-...

Human HEK293 Cells
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1.
TMPY-06986 FGF-8b Protein, Human, Recombinant

NEWENTRY,fibroblast growth factor 8 (androgen-induced),FGF-8...

Human E. coli
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac...
TMPY-04180 PfLDH Protein, P. falciparum, Recombinant (His)

PfLDH,L-lactate dehydrogenase

P. falciparum E. coli
Plasmodium falciparum lactate dehydrogenase (PfLDH) is a key enzyme for energy generation of malarial parasites and is considered to be a potential antimalarial target. The ability of PfLDH- or PfIDEh-based immuno-PCR assays to detect <1 parasite/microL suggests that improvements of bound antibody sensor technology may greatly increase the sensitivity of malaria rapid diagnostic tests. The PfLDH test could be used to detect failures and, therefore, to assess anti-malarial efficacy.
TMPY-00005 FGF-8a Protein, Human, Recombinant

fibroblast growth factor 8 (androgen-induced),FGF-8,AIGF,NEW...

Human E. coli
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac...
TMPY-02279 Nucleoside phosphorylase/PNP Protein, Human, Recombinant (His)

PUNP,PRO1837,purine nucleoside phosphorylase,NP

Human E. coli
Purine nucleoside phosphorylase (PNP) is a purine-metabolizing enzyme that catalyzes the reversible phosphorolysis of 6-oxypurine (deoxy)nucleosides to their respective bases and (deoxy)ribose-1-phosphate. It is a key enzyme in the purine salvage pathway of mammalian cells. Purine nucleoside phosphorylase is a transferase that catalyzes the addition of phosphate and removal of a purine base from guanosine and similar nucleosides.PNP defects result in metabolic abnormalities and fatal T cell immu...
TMPK-00369 HGF Protein, Human, Recombinant (hFc)

HGF,F-TCF,HGFB,SF,F-TCFB,肝细胞生长因子,DFNB39,Hepatopoietin-A,HPTA

Human HEK293 Cells
Hepatocyte growth factor (HGF) is an important component of the pathophysiology of IR, with increased levels in most common IR conditions, including obesity. HGF has a role in the metabolic flux of glucose in different insulin sensitive cell types; plays a key role in β-cell homeostasis; and is capable of modulating the inflammatory response.HGF plays a central role in these metabolic disorders,HGF levels could be employed as a biomarker for disease status/progression, and HGF/c-Met signaling pa...
TMPH-03764 YAP1 Protein, Human, Recombinant (His)

YAP1-2gamma,YAP2L,YAP65

Human P. pastoris (Yeast)
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1,...
TMPY-03221 Intrinsic Factor Protein, Human, Recombinant (His)

IF,IFMH,gastric intrinsic factor (vitamin B synthesis),INF,T...

Human HEK293 Cells
Gastric intrinsic factor, also known as GIF, belongs to the of the cobalamin transport protein family. It is a glycoprotein produced by the parietal cells of the stomach. Gastric intrinsic factor plays a key role in the absorption of vitamin B12 on in the small intestine. Vitamin B12 bounds to haptocorrin after entry into the stomach. The resulting complex enters the duodenum, where pancreatic enzymes digest haptocorrin. In the less acidic environment of the small intestine, B12 can then bind to...
TMPY-00817 Granzyme B/GZMB Protein, Human, Recombinant (His)

CGL1,CTLA1,CSP-B,CTSGL1,HLP,SECT,CSPB,granzyme B (granzyme 2...

Human HEK293 Cells
Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the target cells depending on another membrane-binding granule protein, perforin, results in the activation of effector caspases and mitochondrial depolarization through caspase-dependent and -independent pathways, and consequently induces rapid cell apoptosis. Over 3 substrates of G...
TMPY-04069 Neurotrophin 3 Protein, Human, Recombinant

NGF2,HDNF,NT-3,neurotrophin 3,NGF-2,NT3

Human E. coli
NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. NTF3 is a key mediator of neuronal development during the early neurogenic period. NTF3 is a novel target gene of POU3F2 and that the POU3F2/NTF3 pathway plays a role in the process of neuronal differentiation. ...
TMPY-00539 GSTA1 Protein, Human, Recombinant (His)

glutathione S-transferase alpha 1,GTH1,GST2,glutathione S-tr...

Human HEK293 Cells
GSTA1 (Glutathione S-Transferase Alpha 1) is a Protein Coding gene. This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds. Glutathione S-transferases (GSTs) are involved in the detoxification of carcinogens and may be linked to carcinogenesis. As a vital component of GSTs, GSTA1 plays an important role in carcinogenesis. GSTA1 expression may be a target molecule in the early diagnosis and treatment of lung cancer. Human colonic adeno...
TMPY-02953 TEM8/ANTXR1 Protein, Human, Recombinant (hFc)

ATR,TEM8,anthrax toxin receptor 1,GAPO

Human HEK293 Cells
ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are serine-threonine protein kinases and belongs to the phosphatidylinositol 3' kinase-like kinase (PIKK) family. Upon recruitment by the DNA damage binding proteins/complexes (ATRIP for ATR; MRN for ATM), ATM/ATR initiate the DNA damage checkpoint by phosphorylating a number of key pro...
TMPY-03650 BirA Protein, E. coli, Recombinant (His & MBP)

BirA,dhbB,bioR

E. coli E. coli
The enzyme BirA is a key reagent because of its ability to biotinylate proteins at a specific residue in a recognition sequence. This enzyme is used to biotinylate the C termini of membrane proteins, allowing these proteins to be tetramerized by binding to streptavidin. Because of the specificity of the biotinylation at the C terminus, the orientation of the membrane proteins on the streptavidin is equivalent to that of the native protein on the cell surface. These tetrameric proteins can be use...
TMPY-02779 Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)

thyroid peroxidase,MSA,TPX,TDH2A

Human Baculovirus Insect Cells
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two i...
TMPJ-01466 Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)

OPG,Tumor Necrosis Factor Receptor Superfamily Member 11B,OC...

Human HEK293 Cells
TNFRSF11B is a secreted protein, containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits nuclear kappa B (NF-κB) which is a central and rapid acting transcription factor for immune-related genes, and a key regulator of inflammation, innate immunity, and cell survival and differentiation. TNFRSF11B levels are influenced by voltage-dependent calcium channelsCav1.2. TNF...
TMPY-01736 COX-2 Protein, Human, Recombinant (His)

GRIPGHS,PHS-2,hCox-2,COX-2,PGHS-2,prostaglandin-endoperoxide...

Human Baculovirus Insect Cells
PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS). PTGS, also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. PTGS2 is overexpressed in many cancers. The overexpression of PTGS2 along with increased angiogenesis and GLUT-1 expression ...
TMPY-02521 HIST3H2A Protein, Human, Recombinant

histone cluster 3, H2a,MGC3165

Human E. coli
Histones are a complex family of highly conserved basic proteins responsible for packaging chromosomal DNA into nucleosomes. There are subtype diversities: H1, H2A, H2B, and H3 or H4. It has become more and more evident that histone modifications are key players in the regulation of chromatin states and dynamics as well as in gene expression. Therefore, histone modifications and the enzymatic machinery that set them are crucial regulators that can control cellular proliferation, differentiation,...
TMPY-01806 CD9 Protein, Human, Recombinant (His)

BTCC-1,DRAP-27,TSPAN29,MRP-1,CD9 molecule,MIC3,TSPAN-29

Human HEK293 Cells
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d...
TMPY-04552 AKT1 Protein, Human, Recombinant (His)

RAC-ALPHA,v-akt murine thymoma viral oncogene homolog 1,RAC,...

Human Baculovirus Insect Cells
v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to insulin, insulin-like growth factor 1 (IGF1), and glucose. AKT1 also plays a key role in the regulation of both muscle cell hypertrophy and atrophy. AKT1 activity is required for physiologic cardiac growth in response to IGF1 stimulation or exercise training. In contrast, AKT1 ac...
TMPY-04396 C-ABL/ABL1 Protein, Human, Recombinant (GST)

v-abl,ABL,JTK7,ABL proto-oncogene 1, non-receptor tyrosine k...

Human Baculovirus Insect Cells
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity an...
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重组蛋白

ATG14 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01003
Species: Human
Expression System: E. coli
Monkeypox Virus (MPXV) A5L Protein (His)
Cat.No: TMPY-06588
Species: MPXV
Expression System: E. coli
Influenza A H5N8 (A/turkey/California/K1500169-1.2/2015) Hemagglutinin/HA1 Protein (His)
Cat.No: TMPY-04738
Species: H5N8
Expression System: HEK293 Cells
Monkeypox Virus (MPXV) B6R Protein (His)
Cat.No: TMPY-06569
Species: MPXV
Expression System: HEK293 Cells
Monkeypox Virus (MPXV) Protein A29 (His)
Cat.No: TMPY-06522
Species: MPXV
Expression System: E. coli
Monkeypox Virus (MPXV) B6R Protein (His), Biotinylated
Cat.No: TMPY-06606
Species: MPXV
Expression System: HEK293 Cells
Influenza A H7N3 (A/turkey/Italy/214845/2002) Hemagglutinin/HA1 Protein (His)
Cat.No: TMPY-04174
Species: H7N3
Expression System: HEK293 Cells
Influenza A H7N1 (A/turkey/Italy/4602/99) Hemagglutinin/HA1 Protein (His)
Cat.No: TMPY-00370
Species: H7N1
Expression System: HEK293 Cells
Monkeypox Virus (MPXV) C19L Protein (His)
Cat.No: TMPY-06602
Species: MPXV
Expression System: Baculovirus Insect Cells
Monkeypox Virus (MPXV) L1R Protein (His)
Cat.No: TMPY-06523
Species: MPXV
Expression System: E. coli
A35R Protein, Monkeypox virus, Recombinant (His)
Cat.No: TMPK-01253
Species: Monkeypox virus
Expression System: HEK293 Cells
A29 Protein, Monkeypox virus, Recombinant (His)
Cat.No: TMPK-01123
Species: Monkeypox virus
Expression System: E. coli
Influenza A H7N3 (A/turkey/Italy/214845/2002) Hemagglutinin/HA Protein (His)
Cat.No: TMPY-04166
Species: H7N3
Expression System: Baculovirus Insect Cells
Monkeypox Virus (MPXV) Envelope protein E8L Protein (His)
Cat.No: TMPY-06562
Species: MPXV
Expression System: Baculovirus Insect Cells
Monkeypox Virus (MPXV) Protein A35 (His)
Cat.No: TMPY-06529
Species: MPXV
Expression System: HEK293 Cells
Influenza A H5N8 (A/turkey/Ireland/1378/1983) Hemagglutinin/HA Protein (His)
Cat.No: TMPY-00421
Species: H5N8
Expression System: Baculovirus Insect Cells
Influenza A H5N8 (A/turkey/Germany-MV/R2472/2014 ) Hemagglutinin/HA1 Protein (His)
Cat.No: TMPY-04606
Species: H5N8
Expression System: HEK293 Cells
Monkeypox Virus (MPXV) M1R Protein (His)
Cat.No: TMPY-06568
Species: MPXV
Expression System: HEK293 Cells
A30 Protein, Monkeypox virus, Recombinant (His)
Cat.No: TMPK-01116
Species: Monkeypox virus
Expression System: HEK293 Cells
E8L Protein, Monkeypox virus, Recombinant (His)
Cat.No: TMPK-01252
Species: Monkeypox virus
Expression System: E. coli
M1R Protein, Monkeypox virus, Recombinant (His)
Cat.No: TMPK-01250
Species: Monkeypox virus
Expression System: HEK293 Cells
L1R Protein, Monkeypox virus, Recombinant (His)
Cat.No: TMPK-01251
Species: Monkeypox virus
Expression System: E. coli
Monkeypox Virus (MPXV) A33R Protein (His & GST)
Cat.No: TMPY-06584
Species: MPXV
Expression System: E. coli
Monkeypox Virus (MPXV) Envelope protein H3 (His)
Cat.No: TMPY-06540
Species: MPXV
Expression System: HEK293 Cells
Monkeypox Virus (MPXV) I1L Protein (His)
Cat.No: TMPY-06539
Species: MPXV
Expression System: E. coli
Influenza A H5N8 (A/turkey/Ireland/1378/1983) Hemagglutinin/HA1 Protein (His)
Cat.No: TMPY-00202
Species: H5N8
Expression System: HEK293 Cells
Influenza A H5N1 (A/turkey/Turkey/1/2005) Hemagglutinin/HA Protein (His)
Cat.No: TMPY-01128
Species: H5N1
Expression System: HEK293 Cells
Influenza A H5N8 (A/turkey/Germany-MV/R2472/2014) Hemagglutinin/HA Protein (His)
Cat.No: TMPY-04840
Species: H5N8
Expression System: Baculovirus Insect Cells
OXCT1 Protein, Human, Recombinant (His)
Cat.No: TMPH-02151
Species: Human
Expression System: E. coli
R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His)
Cat.No: TMPY-02115
Species: Human
Expression System: HEK293 Cells
TGFBR1 Protein, Human, Recombinant (mFc & Avi)
Cat.No: TMPK-00305
Species: Human
Expression System: HEK293 Cells
FGF-8b Protein, Human, Recombinant
Cat.No: TMPY-06986
Species: Human
Expression System: E. coli
PfLDH Protein, P. falciparum, Recombinant (His)
Cat.No: TMPY-04180
Species: P. falciparum
Expression System: E. coli
FGF-8a Protein, Human, Recombinant
Cat.No: TMPY-00005
Species: Human
Expression System: E. coli
Nucleoside phosphorylase/PNP Protein, Human, Recombinant (His)
Cat.No: TMPY-02279
Species: Human
Expression System: E. coli
HGF Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00369
Species: Human
Expression System: HEK293 Cells
YAP1 Protein, Human, Recombinant (His)
Cat.No: TMPH-03764
Species: Human
Expression System: P. pastoris (Yeast)
Intrinsic Factor Protein, Human, Recombinant (His)
Cat.No: TMPY-03221
Species: Human
Expression System: HEK293 Cells
Granzyme B/GZMB Protein, Human, Recombinant (His)
Cat.No: TMPY-00817
Species: Human
Expression System: HEK293 Cells
Neurotrophin 3 Protein, Human, Recombinant
Cat.No: TMPY-04069
Species: Human
Expression System: E. coli
GSTA1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00539
Species: Human
Expression System: HEK293 Cells
TEM8/ANTXR1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02953
Species: Human
Expression System: HEK293 Cells
BirA Protein, E. coli, Recombinant (His & MBP)
Cat.No: TMPY-03650
Species: E. coli
Expression System: E. coli
Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)
Cat.No: TMPY-02779
Species: Human
Expression System: Baculovirus Insect Cells
Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)
Cat.No: TMPJ-01466
Species: Human
Expression System: HEK293 Cells
COX-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01736
Species: Human
Expression System: Baculovirus Insect Cells
HIST3H2A Protein, Human, Recombinant
Cat.No: TMPY-02521
Species: Human
Expression System: E. coli
CD9 Protein, Human, Recombinant (His)
Cat.No: TMPY-01806
Species: Human
Expression System: HEK293 Cells
AKT1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04552
Species: Human
Expression System: Baculovirus Insect Cells
C-ABL/ABL1 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04396
Species: Human
Expression System: Baculovirus Insect Cells
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Cat. No. Product Name Target Signaling Pathways
TMIJ-0518 L-Kynurenine-d4-1

L-Kynurenine-d4-1 是 L-Kynurenine 的氘代化合物。L-Kynurenine 的 CAS 号为 2922-83-0。L-Kynurenine是L-色氨酸的代谢物,是芳香烃受体激动剂,可抑制同种异体 T 细胞增殖并增加恶性 U87 神经胶质瘤细胞侵入胶原基质。
TMID-0071 L-Kynurenine-d4

L-Kynurenine-d4 是 L-Kynurenine 的氘代化合物。L-Kynurenine 的 CAS 号为 2922-83-0。L-Kynurenine是L-色氨酸的代谢物,是芳香烃受体激动剂,可抑制同种异体 T 细胞增殖并增加恶性 U87 神经胶质瘤细胞侵入胶原基质。

同位素标记化合物

L-Kynurenine-d4-1
Cat.No: TMIJ-0518
Synonym:
Target:
L-Kynurenine-d4
Cat.No: TMID-0071
Synonym:
Target:
TargetMol Loading
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