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Cat. No. | Product Name | ||
---|---|---|---|
L2510 | 脂代谢化合物库 | 492 compounds | |
492 个脂代谢相关的化合物集合,可用于高通量和高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T18946 |
Cy3 NHS ester
Cyanine3 NHS ester |
Others | Others |
Cy3 NHS ester (Cyanine3 NHS ester) 是一种荧光染料,用于标记蛋白质、肽、抗体和寡核苷酸中的氨基。 | |||
T27572 |
Ibuprofen diethylaminoethyl ester
Brufen diethylaminoethyl ester,BF-DEAE,BF DEAE |
Others | Others |
Ibuprofen diethylaminoethyl ester (BF DEAE) 具有抗炎活性,可作为局部麻醉剂,可用于研究麻风性神经炎等神经系统疾病。 | |||
T15067 |
DBCO-NHS ester
|
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
DBCO-NHS ester 是一种 ADC 连接剂,可裂解的 3 单元 PEG,还可以用于合成抗体药物共轭物 (ADC)。 | |||
T17014 |
TCO-NHS ester
|
Others; PROTAC Linker | Others; PROTAC |
TCO-NHS ester 是一种 PROTAC linker,属于 alkyl/ether 类。可用于合成 PROTAC 分子。 | |||
T22092 |
Indomethacin heptyl ester
|
COX | Immunology/Inflammation; Neuroscience |
Indomethacin heptyl ester 是 COX-1 和 COX-2 的非选择性抑制剂。 | |||
T9495 |
Haloxyfop methyl ester
|
Others | Others |
Haloxyfop methyl ester 是一种选择性除草剂,脂肪酸合成抑制剂,具有内吸作用。茎叶经处理后,迅速被杂草吸收并传递至全株,水解成酸,抑制根、茎分生组织的生长,导致死亡。 | |||
T18560 |
Propargyl-C1-NHS ester
4-戊炔酸琥珀亚胺酯,4-Pentynoic Acid Succinimidyl Ester |
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
Propargyl-C1-NHS ester (4-Pentynoic Acid Succinimidyl Ester) 是一种不可切割的 ADC 接头,可用于合成抗体偶联药物。 | |||
T19294 |
Docosahexaenoic Acid methyl ester
二十二六烯酸甲酯,Methyl docosahexaenoate,all cis-DHA methyl ester |
Others | Others |
Docosahexaenoic Acid methyl ester (all cis-DHA methyl ester) 是甲基化的二十二碳六烯酸类似物,能够插入膜磷脂中而不被氧化或水解。 | |||
T15991 |
Mal-PEG4-NHS ester
|
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
Mal-PEG4-NHS ester是一种 ADC linker,参与制备 OMV-Mal。 | |||
T17978 |
Fmoc-PEG12-NHS ester
|
Others; PROTAC Linker | Others; PROTAC |
Fmoc-PEG12-NHS ester 是 PEG 类 PROTAC linker。可用于合成 PROTAC 分子。 | |||
T15073 |
DBCO-PEG4-NHS ester
|
PROTAC Linker | PROTAC |
DBCO-PEG4-NHS ester 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T17842 |
DOTA-NHS-ester
|
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
DOTA-NHS-ester 是 affibody 分子的接头,应用于小动物 PET、SPECT 和 CT。 它可用于标记放射治疗剂或成像探针以检测肿瘤。 | |||
T17017 |
TCO-PEG4-NHS ester
|
PROTACs; ADC Linker | Antibody-drug Conjugate/ADC Related; PROTAC |
TCO-PEG4-NHS ester 是一种属于 PEG 类的 PROTAC 连接桥。TCO-PEG4-NHS ester 可用于合成一系列 PROTAC 分子。TCO-PEG4-NHS ester 是一种可降解 (cleavable) 且可用于抗体活性分子结合物 (ADCs) 的合成 ADC 连接桥。 | |||
T14594 |
Biotin-PEG3-NHS ester
|
Others | Others |
Biotin-PEG3-NHS ester 是基于 PEG 结构且可以用来制备 PROTAC 的 PROTAC linker。 | |||
T1547 |
L-Cysteine methyl ester hydrochloride
L-半胱氨酸甲酯盐酸盐,L-Cysteine methyl ester hydrochloride(Acdrile) |
Amino Acids and Derivatives | Metabolism |
L-Cysteine methyl ester hydrochloride (L-Cysteine methyl ester hydrochloride (Acdrile)) 是一种粘痰溶解剂,是镇咳药,可用于缓解大量粘痰引起的呼吸困难。 | |||
T3420 |
CA-074 methyl ester
Cathepsin B Inhibitor IV,CA-074Me |
Cysteine Protease | Proteases/Proteasome |
CA-074 methyl ester (Cathepsin B Inhibitor IV) 是Cathepsin B 的选择性抑制剂,具有保护神经、抗炎、抗癌等多种作用。 | |||
T41143 |
pCPA methyl ester hydrochloride
4-氯-DL-苯基丙氨酸甲酯盐酸盐,4-Chloro-DL-phenylalanine methyl ester hydrochloride |
5-HT Receptor; Hydroxylase | GPCR/G Protein; Metabolism; Neuroscience |
pCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride) 是色氨酸羟化酶抑制剂和5-HT 合成的抑制剂。 pCPA methyl ester hydrochloride 可穿过血脑屏障并降低 5-HT 中枢可用性。 | |||
T17486 |
Azido-PEG12-NHS ester
|
Others; PROTAC Linker | Others; PROTAC |
Azido-PEG12-NHS ester 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T15976 |
Mal-PEG1-NHS ester
|
Others; PROTAC Linker; ADC Linker | Antibody-drug Conjugate/ADC Related; Others; PROTAC |
Mal-PEG1-NHS ester 是一种可裂解的基于 PEG 的 ADC 接头,用于合成抗体-药物偶联物。它也是基于 PEG 的 PROTAC 接头,可用于 PROTAC 的合成。 | |||
T16259 |
N3-PEG4-C2-NHS ester
|
ADC Linker; Antibody-Drug Conjugates (ADCs) | Antibody-drug Conjugate/ADC Related |
N3-PEG4-C2-NHS ester 是一种不可降解的 ADC linker,含 4 个单元 PEG 可用于合成抗体偶联活性分子 (ADC)。 | |||
T14635 |
Bis-PEG3-NHS ester
|
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
Bis-PEG3-NHS ester 是用于抗体-药物偶联的不可切割的 3 单元 PEG 接头。 | |||
T37482 |
Diclofenac methyl ester
|
Others | Others |
Diclofenac methyl ester 是双氯芬酸(diclofenac)的疏水性前药形式,它是一种非甾体抗炎药 (NSAID)。它比双氯芬酸更易溶于肉豆蔻酸异丙酯,但毒性更高。 | |||
T15962 |
Mal-amido-PEG8-NHS ester
|
Others; PROTAC Linker | Others; PROTAC |
Mal-amido-PEG8-NHS ester 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T18467 |
N3-C4-NHS ester
|
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
N3-C4-NHS ester 是一种不可切割的 ADC 接头,用于合成抗体-药物偶联物。 | |||
T4433 |
6-CFDA N-succinimidyl ester
Carboxyfluorescein diacetate succinimidyl |
Others | Others |
6-CFDA N-succinimidyl ester (Carboxyfluorescein diacetate succinimidyl) 能够自发且不可逆地与游离胺结合。在流式细胞术实验中用于追踪哺乳动物细胞和细菌的细胞分裂。与多种细胞透化剂结合使用,作为一种有效的、非破坏性的荧光染料,可快速检测细菌细胞。 | |||
T17791 |
DBCO-PEG3-NHS ester
|
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
DBCO-PEG3-NHS ester是一种可降解的 ADC linker,可用于合成抗体偶联活性分子 。 | |||
T18987 |
Py-BODIPY-NHS ester
|
Autophagy | Autophagy |
Py-BODIPY-NHS ester 是一种具有强紫外吸收能力的小分子染料,可用于标记活细胞和固定细胞。 | |||
T39189 |
3,4,5-Trihydroxycinnamic acid decyl ester
|
Apoptosis | Apoptosis |
3,4,5-Trihydroxycinnamic acid decyl ester 是一种胰腺脂肪酶抑制剂,具有抗癌活性,可诱导细胞凋亡。3,4,5-Trihydroxycinnamic acid decyl ester 具有抗肥胖作用,抑制脂质吸收和积累,可用于研究乳腺癌和前列腺癌。 | |||
T41323 |
Dihomo-γ-Linolenic acid methyl ester
|
Others | Others |
Dihomo-γ-Linolenic acid methyl ester 是 Dihomo-γ-Linolenic acid 的甲酯形式,Dihomo-γ-Linolenic acid 具有抗炎和抗增殖作用。 | |||
T18794 |
Tetrazine-Ph-NHCO-C3-NHS ester
|
Others; PROTAC Linker | Others; PROTAC |
Tetrazine-Ph-NHCO-C3-NHS ester是一种源于PEG的PROTACs合成连接剂。 | |||
T41321 |
Docosahexaenoic acid ethyl ester
Ethyl docosahexaenoate |
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) 通过诱导小鼠纹状体脂质过氧化增强6-羟基多巴胺诱导的神经元损伤,可用于研究视网膜或神经元氧化疾病。 | |||
T19147 |
5-ALA benzyl ester hydrochloride
Benzyl-ALA hydrochloride |
Others; Endogenous Metabolite | Metabolism; Others |
5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) 是一种原卟啉前体,可用作光检测器。5-ALA benzyl ester hydrochloride 在结肠癌细胞系中可以诱导原卟啉 IX (PPIX) 的积聚。 | |||
T38432 |
Cyanine5 NHS ester chloride
|
Others | Others |
Cyanine5 NHS ester chloride 是一种具有红色荧光的活性染料,需要少量的有机共溶剂(如DMF 或DMSO)用于标记肽、蛋白质和寡核苷酸中的氨基。 | |||
T17372 |
Ald-Ph-NHS ester
|
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
Ald-Ph-NHS ester 是用于抗体-药物偶联的不可切割接头。 | |||
T18468 |
N3-C5-NHS ester
叠氮-C5-琥珀酰亚胺酯 |
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
N3-C5-NHS ester 是一种不可切割的 ADC 接头,用于合成抗体-药物偶联物。 | |||
T9829 |
5,6-DIAMINOPYRIDINE-3-CARBOXYLIC ACID METHYL ESTER
|
Others | Others |
5,6-DIAMINOPYRIDINE-3-CARBOXYLIC ACID METHYL ESTER 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T9829,CAS号为 104685-76-9。 | |||
T17694 |
Br-C10-methyl ester
11-溴代十一烷酸甲酯 |
Others; PROTAC Linker | Others; PROTAC |
Br-C10-methyl ester 是一种属于 alkyl/ether 类的 PROTAC linker,可用于一系列 PROTAC 分子的合成。PROTAC 分子含有两个通过 linker 连接的不同配体,一种是 VHL 配体部分,另一种是靶蛋白配体。 | |||
T15956 |
Mal-amido-PEG4-NHS ester
N-[15-[(2,5-二氧代-1-吡咯烷基)氧基]-15-氧代-3,6,9,12-四氧杂十五烷-1-基]-2,5-二氢-2,5-二氧代-1H-吡咯-1-丙酰胺 |
Others; PROTAC Linker | Others; PROTAC |
Mal-amido-PEG4-NHS ester 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T18476 |
N3-Ph-NHS ester
琥珀酰亚胺基 4-叠氮基苯甲酸酯 |
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
N3-Ph-NHS ester 是一种不可切割的 ADC 接头,用于合成抗体-药物偶联物。 | |||
T40122 |
L-Histidine benzyl ester bistosylate
|
Others | Others |
L-Histidine benzyl ester bistosylate可作为HutP(一种RNA结合蛋白)的激活剂。 | |||
T17561 |
Biotin-PEG12-NHS ester
生物素十二聚乙二醇琥珀酰亚胺酯 |
Others; PROTAC Linker | Others; PROTAC |
Biotin-PEG12-NHS ester 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T25865 |
NG-Nitroarginine methyl ester
ω-Nitroarginine methyl,L-NAME |
NO Synthase | Immunology/Inflammation |
NG-Nitroarginine methyl ester (ω-Nitroarginine methyl) 是一种非选择性一氧化氮合酶抑制剂。它已在实验中用于诱发高血压。 | |||
T17677 |
Boc-NH-PEG3-NHS ester
氨基叔丁酯-三聚乙二醇-NHS 酯 |
Others; PROTAC Linker | Others; PROTAC |
Boc-NH-PEG3-NHS ester 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T11013L2 |
Levorotation nimorazole phosphate ester TFA
|
Others | Others |
Levorotation nimorazole phosphate ester TFA 是一种抗厌氧菌和抗原虫感染的试剂。 | |||
T15324 |
Fmoc-NH-PEG8-NHS ester
FMOC-N-酰氨基-DPEG(R)8-NHS酯 |
PROTAC Linker | PROTAC |
Fmoc-NH-PEG8-NHS ester 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T10951 |
Dabigatran ethyl ester hydrochloride
N-[[2-[[[4-(氨基亚氨甲基)苯基]氨基]甲基]-1-甲基-1H-苯并咪唑-5-基]羰基]-N-(2-吡啶基)-BETA-丙氨酸乙酯盐酸盐 |
Others; Thrombin | Others; Proteases/Proteasome |
Dabigatran ethyl ester hydrochloride 是一种核糖基二氢烟酰胺脱氢酶抑制剂,IC50=0.8 μM,也是一种凝血酶的抑制剂。 | |||
FL0195 |
N-Boc-4-hydroxy-L-proline methyl ester
|
Others; ADC Linker | Antibody-drug Conjugate/ADC Related; Others |
N-Boc-cis-4-hydroxy-L-proline methyl ester为不可降解(non-cleavable)的ADC linker,用于抗体药物偶联体(ADCs)合成。该化合物同时作为基于烷基链(alkyl chain)的PROTAC linker,适用于PROTAC合成。 | |||
T60663L |
Oseltamivir acid methyl ester hydrochloride
|
Others | Others |
Oseltamivir acid methyl ester hydrochloride 是奥司他韦酸的前体形式。它通过羧酸酯酶1 (CES1) 转化为奥司他韦酸。 | |||
T11013L1 |
Dextrorotation nimorazole phosphate ester TFA
|
Others | Others |
Dextrorotation nimorazole phosphate ester TFA 是一种抗厌氧菌和抗原虫感染的试剂。 | |||
T64390 |
Triclopyr 2-butoxyethyl ester
Triclopyr-butotyl |
Others | Others |
Triclopyr 2-butoxyethyl ester (Triclopyr-butotyl) 是一种生物活性物质。Triclopyr 2-butoxyethyl ester 对蜜蜂有毒性。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T10886 |
Crocetine dimethyl ester
Dimethylcrocetin |
Antioxidant | oxidation-reduction |
Crocetine dimethyl ester (Dimethylcrocetin) 是一种藏红花素衍生物,具有抗氧化活性,抑制 AChE 活性,抑制细胞生长分化。 | |||
T7068 |
Eicosapentaenoic acid ethyl ester
Icosapent ethyl,顺-二十碳五烯酸乙酯,EPA ethyl ester,Ethyl eicosapentaenoate |
Others; Endogenous Metabolite | Metabolism; Others |
Eicosapentaenoic acid ethyl ester (Ethyl eicosapentaenoate) 是 一种ω-3 脂肪酸剂和人内源性代谢物。 | |||
TN1427 |
Baicalin methyl ester
|
Anti-infection | Microbiology/Virology |
Baicalin methyl ester 是黄芩苷根的一种成分。 | |||
T0603 |
Phthalic acid mono-2-ethylhexyl ester
Phthalic Acid Monooctyl Ester,邻苯二甲酸单乙基己基酯 |
P450; Endogenous Metabolite | Metabolism |
Phthalic acid mono-2-ethylhexyl ester (Phthalic Acid Monooctyl Ester) 是diethylhexyl phthalate (DEHP) 的主要生物活性代谢物,能够抑制 CYP17 的 17,20 裂合酶特性。 | |||
TN5845 |
Neochlorogenic acid methyl ester
5-O-Caffeoylquinic acid methyl ester,Methyl 3-caffeoylquinate,GIP (1-39) acetate(725474-97-5 Free base),Methyl neochlorogenate,新绿原酸甲酯 |
Antioxidant; HBV | Microbiology/Virology; oxidation-reduction |
Neochlorogenic acid methyl ester (5-O-Caffeoylquinic acid methyl ester) 来源于毛蒿和黑色苦莓(Aronia melanocarpa)果实。Neochlorogenic acid methyl ester 显示出抗 HBV 活性、抗氧化活性和醌还原酶活性,CD 为 6.7 μM。 | |||
T2S0842 |
Scutellarin methyl ester
Scutellarin methylester,野黄芩苷甲酯 |
Others | Others |
Scutellarin methyl ester (3-Oxotirucallenoic Acid) 是一种灯盏花素的成分, 其中灯盏花素是灯盏花中几种黄酮类化合物的粗提物。 | |||
TN4562 |
Oleoside 11-methyl ester
木樨榄苷-11-甲酯,Methyloleoside |
Others | Others |
Oleoside 11-methyl ester (Methyloleoside) 是一种对 Hep-G2 细胞具有强细胞毒作用的裂环烯醚萜苷。 | |||
TJS0123 |
Guvacine ethyl ester
槟榔碱,PT00442-2 |
Others | Others |
Guvacine ethyl ester (Arecoline) 是一种生物碱,存在于槟榔中,可用于 GABA 摄取抑制剂的合成。 | |||
T3896 |
Shanzhiside methyl ester
三栀子甙甲酯,山芝皂苷甲酯 |
Glucagon Receptor | GPCR/G Protein |
Shanzhiside methyl ester 是一种小分子胰高血糖素样肽 1 受体激动剂,分离自轮状乳杆菌,能够诱导抗异常性痛觉耐受。 | |||
T21504 |
γ-Linolenic Acid methyl ester
Methyl gamma-linolenate,γ-亚麻酸甲酯 |
LTR | Immunology/Inflammation |
γ-Linolenic Acid methyl ester (Methyl gamma-linolenate) 是一种弱白三烯 B4 (LTB4) 受体拮抗剂。 | |||
TN1261 |
3-O-Caffeoylquinic acid methyl ester
|
Others | Others |
3-O-Caffeoylquinic acid methyl ester 是 Pyrrosia calvata 的成分之一。 | |||
T3S0006 |
(E)-Ferulic acid methyl ester
Methyl ferulate,Methyl (E)-ferulate,(E)-阿魏酸甲酯 |
IL Receptor; p38 MAPK; TNF; COX; NO Synthase; JNK; Antifection | Apoptosis; Immunology/Inflammation; MAPK; Microbiology/Virology; Neuroscience |
(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) 具有较强 DPPH 和 ABTS+自由基清除特性。 | |||
T7929 |
L-Aspartic Acid 4-Benzyl Ester
|
Others | Others |
L-Aspartic Acid 4-Benzyl Ester 是一种螯合剂,与金属离子形成稳定的络合物,已用于研究金属离子对酶活性的影响,以及研究金属离子在基因表达调控中的作用等。 | |||
T3S0870 |
Paederosidic acid methyl ester
鸡屎藤苷酸甲酯,紫草酸甲酯 |
ATPase; Potassium Channel; NO Synthase | Immunology/Inflammation; Membrane transporter/Ion channel |
Paederosidic acid methyl ester 是 ATP 敏感的 K+channel 通道激活剂,分离自 P. scandens。它通过激活脑中和脊髓水平中 ATP 敏感型 K+通道提高了痛觉阈值,表现出显著的中枢缓解疼痛活性。 | |||
T6429 |
Caffeic Acid Phenethyl Ester
Phenylethyl Caffeate,咖啡酸苯乙酯,CAPE |
Apoptosis; NF-κB | Apoptosis; NF-κB |
Caffeic Acid Phenethyl Ester (Phenylethyl Caffeate) 是咖啡酸的苯乙醇酯,是蜂巢蜂胶的生物活性成分。它抑制核转录因子 NF-kappa B 的激活,具有抗肿瘤、细胞保护和免疫调节活性。它抑制 PDGF 诱导的血管平滑肌细胞增殖。 | |||
T13808 |
p-Coumaric Acid Ethyl Ester
对香豆酸乙酯,Ethyl (E)-p-hydroxycinnamate,Ethyl trans-4-hydroxycinnamate |
Others; Drug Metabolite | Metabolism; Others |
p-Coumaric Acid Ethyl Ester (Ethyl (E)-p-hydroxycinnamate) 是 p-Coumaric acid 的乙酯形式。p-Coumaric Acid 是一种免疫抑制剂, 能够用于自身免疫性炎性疾病 (如类风湿关节炎) 的研究。 | |||
TL0004 |
FERULIC ACID METHYL ESTER
阿魏酸甲酯,Methyl ferulate,Methyl 4'-hydroxy-3'-methoxycinnamate |
p38 MAPK; Autophagy | Autophagy; MAPK |
FERULIC ACID METHYL ESTER (Methyl ferulate) 是从大百部中分到的阿魏酸衍生物,具有抗氧化和抗炎作用。在原发性骨髓源性巨噬细胞中,它抑制 COX-2 的表达,降低 p-p38和 p-JNK 的水平。它能够透过细胞膜和血脑屏障,清除自由基,可研究神经退行性疾病。 | |||
T3S0208 |
Hederagenin 28-O-beta-D-glucopyranosyl ester
Hederagenin-28-beta-D-glucopyranoside,常春苷元-28-BETA-D-吡喃葡萄糖苷,常春藤皂苷元28-O-beta-D-吡喃葡萄糖酯 |
Others | Others |
Hederagenin-28-beta-D-glucopyranoside 是一种分离自Ilex cornuta中的三萜皂苷,能够保护H2O2诱导的心肌细胞免于损伤。 | |||
TN7129 |
Methyl maslinate
马斯里酸甲酯,Maslinic acid methyl ester,Crategolic acid methyl ester |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Methyl maslinate (Maslinic acid methyl ester) 是一种具有强心和抗心律失常特性的 β-肾上腺素受体拮抗剂。Methyl maslinate 可用于高血压研究。 | |||
T2P2810 |
Methyl Linoleate
Linoleic acid methyl ester,亚油酸甲酯,Telfairic Acid methyl ester |
Antioxidant | oxidation-reduction |
Methyl Linoleate (Telfairic Acid methyl ester) 是一种 Sageretia thea 果实的主要活性成分,能够下调小眼畸形相关转录因子和酪氨酸酶相关蛋白,是一种主要的抗黑色素生成化合物。 | |||
T31708 |
Ethyl caprate
Decanoic acid, ethyl ester,Capric acid ethyl ester,Ethyl decylate,Ethyl caprinate,Ethyl decanoate |
||
Ethyl caprate (Ethyl decanoate) 是一种存在于葡萄酒中的香料和食品添加剂,可用于食品、香精和化妆品等方面。 | |||
T4S1050 |
Pristimerin
扁塑藤素,Celastrol methyl ester |
NF-κB; Antibacterial | Microbiology/Virology; NF-κB |
Pristimerin (Celastrol methyl ester) 是一种可逆的单酰基甘油脂肪酶高效抑制剂,IC50值为93 nM。 | |||
T21157 |
Sebacic acid dimethyl ester
Sebacic acid, dimethyl ester (8CI),Dimethyl sebacate,Decanedioic acid, 1,10-dimethyl ester,Decanedioic acid, dimethyl ester |
||
Dimethyl sebacate was used in the biosynthesis of oligomeric sebacates, lubricant oils. Dimethyl sebacate was a convenient starting material for cyclization of N-Succinylglycine dimethyl ester. Dimethyl sebacate was also used to prepare polytetramethylene | |||
TN6743 |
ETHYL OCTANOATE
辛酸乙酯,CAPRYLIC ACID ETHYL ESTER |
Others | Others |
ETHYL OCTANOATE (CAPRYLIC ACID ETHYL ESTER) 是一种天然产物。 | |||
T2O2667 |
Methyl Oleate
油酸甲酯,oleic acid methyl ester,Methyl cis-9-Octadecenoate,cis-9-Octadecenoic Acid methyl ester |
Others; Antioxidant | Others; oxidation-reduction |
Methyl oleate 是脂肪酸甲酯。它能够显著提高抗氧化能力,但也明显削弱二烷基二硫代磷酸锌的抗磨能力。 | |||
TN3952 |
copyranosyl ester
ent-6,9-Dihydroxy-15-oxo-16-kauren-19-oic acid beta-D-glucopyranosyl ester |
Others | Others |
copyranosyl ester 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3952,CAS号为 81263-98-1。 | |||
T2744 |
Methyl Cholate
胆酸甲酯,Cholic acid methyl ester |
Others | Others |
Methyl Cholate 是胆酸的甲酯形式。其中胆酸是一种由肝脏产生的主要胆汁酸,由胆固醇合成。Methyl Cholate 具有抗炎抗肿瘤活性。 | |||
TN6710 |
Methyl acetylsalicylate
ACETYLSALICYLIC ACID METHYL ESTER,乙酰水杨酸甲酯 |
Others | Others |
Methyl acetylsalicylate (ACETYLSALICYLIC ACID METHYL ESTER) 是一种从豌豆中分离出来的天然产物。抑制胶原蛋白诱导的人富含血小板的血浆聚集。 | |||
TN7052 |
Crocin III
西红花苷 III,Crocetin-mono-(β-D-gentiobiosyl)-ester |
Others | Others |
Crocin III (Crocetin-mono-(β-D-gentiobiosyl)-ester) 是一种来自于藏红花 (Crocus sutivusL)的藏红花素。Crocins 可用作香料和着色剂。Crocins 具有抗炎作用,能够抑制肿瘤细胞的细胞生长。 | |||
T19424 |
Methyl mycophenolate
Mycophenolic Acid Methyl Ester,霉酚酸酯杂质E |
Others | Others |
Methyl mycophenolate (Mycophenolic Acid Methyl Ester) 是一种霉酚酸的甲酯,存在于海洋真菌Phaeosphaeria spartinae 中。 | |||
T8067 |
Methyl Nonadecanoate
Nonadecanoic Acid methyl ester,正十九酸甲酯 |
Others | Others |
Methyl Nonadecanoate (Nonadecanoic Acid methyl ester)是一种内标物,能够用于生物柴油中脂肪酸甲酯含量的测定。 | |||
T5667 |
Octyl acetate
Acetic acid octyl ester,醋酸辛酯 |
Others | Others |
Octyl acetate (Acetic acid octyl ester) 是一种野生欧洲防风草 (Pastinaca sativa) 的管子或油管中精油的主要成分,具有抗氧化作用。 | |||
T3727 |
Methyl syringate
Syringic Acid Methyl Ester,丁香酸甲酯 |
TRP/TRPV Channel | Membrane transporter/Ion channel |
Methyl syringate (Syringic Acid Methyl Ester) 是水仙花蜜的化学标记物,是有效的细菌和真菌漆酶酚介质。它也是TRPA1激动剂。 | |||
T38552 |
Dehydrosoyasaponin I methyl ester
大豆皂苷BE甲酯,Soyasaponin Be methyl ester,DHS-Imethylester |
Others | Others |
Dehydrosoyasaponin I methyl ester, also known as Soyasaponin Be methyl ester, is a saponin compound that is naturally occurring in Trifolium alexandrinum. | |||
TN7194 |
AC-PHE-OME
Methyl N-acetyl-L-phenylalaninate,N-乙酰基-L-苯丙氨酸甲酯,N-Acetyl-L-phenylalanine methyl ester,N-acetyl phenylalanine methyl ester |
Others | Others |
AC-PHE-OME (Methyl N-acetyl-L-phenylalaninate) 是一种海洋来源的天然产物,存在于 Family Jaspidae。 | |||
T13966 |
Wogonin 7-O-beta-D-glucuronide methyl ester
Wogonoside methyl ester |
Others | Others |
Wogonin 7-O-beta-D-glucuronide methyl ester is a natural product isolated from Huanglian Jiedutang. | |||
T2O2666 |
Methyl stearate
Stearic Acid methyl ester,硬脂酸甲酯,Methyl Octadecanoate |
Others | Others |
Methyl stearate (Methyl Octadecanoate) 是大豆和油菜籽生物柴油的组分,分离自 Rheum palmatumL 中。 | |||
TN6999 |
Methyl elaidate
(E)-Methyl octadec-9-enoate,Elaidic Acid Methyl Ester,Methyl (9E)-octadec-9-enoate |
||
Methyl elaidate (Elaidic Acid Methyl Ester) 是一种合成脂肪酸甲酯,可作为植物保护产品配方中的佐剂。 | |||
T3S0013 |
Ethyl trans-caffeate
咖啡酸乙酯,Ethyl caffeate,Caffeic Acid Ethyl Ester |
Others | Others |
Ethyl trans-caffeate (Caffeic Acid Ethyl Ester) 具有抗炎作用。 它是一种有前途的天然化合物,未来在慢性肝病中的应用。它是一种有效的化学预防化合物,可防止因太阳紫外线照射引起的皮肤癌变。它是与人胰腺α-淀粉酶复合的代表性抑制剂的高分辨率结构。 它强烈抑制 JB6 Cl41细胞的肿瘤转化,无毒性。 PI3K、ERK1/2 和 p38 激酶活性在体外通过与 HOEC 直接结合而受到抑制。 | |||
TN7075 |
Linocinnamarin
3-[4-(beta-D-Glucopyranosyloxy)phenyl]acrylic acid methyl ester |
Phospholipase; Syk | Angiogenesis; Metabolism; Tyrosine Kinase/Adaptors |
Linocinnamarin (3-[4-(beta-D-Glucopyranosyloxy)phenyl]acrylic acid methyl ester) 是从 Fragaria ananassa Duch 中分离出来的。 它对抗原刺激脱粒的抑制主要是由于 Syk/磷脂酶 Cgamma (PLCgamma) 途径的失活。 | |||
T3982 |
Vulpinic Acid
狐衣酸,Vulpic acid,Pulvinic acid methyl ester |
Others | Others |
Vulpinic Acid (Pulvinic acid methyl ester) 是地衣代谢物,可降低人脐静脉内皮细胞 (HUVEC) 中 H2O2诱导的ROS,氧化应激和氧化应激相关损伤,可作用于厌氧菌、葡萄球菌及肠球菌。它对脉粥样硬化的研究具有潜在的价值。 | |||
T1368 |
Methyl 3,4-dihydroxybenzoate
3,4-Dihydroxybenzoic acid methyl ester,Methyl protocatechuate,原儿茶酸甲酯,3,4-二羟基苯甲酸甲酯,Protocatechuic acid methyl ester |
Apoptosis; Antioxidant; Nrf2 | Apoptosis; Immunology/Inflammation; oxidation-reduction |
Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester) 是绿茶中发现的主要代谢产物,是一种多酚,有抗氧化和抗炎作用。 | |||
T0650 |
Phenyl acetate
Acetylphenol,乙酸苯酯,Phenol acetate,Acetic acid phenyl ester |
Others; Endogenous Metabolite | Metabolism; Others |
Phenyl acetate (Acetic acid phenyl ester) 是苯丙氨酸的芳香脂肪酸代谢物,具有潜在的抗肿瘤活性。苯乙酸酯天然存在于哺乳动物中,可诱导肿瘤细胞分化、生长抑制和凋亡。 | |||
T0729 |
Benzyl benzoate
Ascabiol,Novoscabin,Scabitox,苯甲酸苄酯,Benzoic acid benzyl ester |
Parasite | Microbiology/Virology |
Benzyl benzoate (Benzoic acid benzyl ester) 是化妆品中的香料成分,可研究疥疮和蠕形螨相关的炎症性皮肤病。 | |||
T22366 |
Methyl cyclohexanecarboxylate
Hexahydrobenzoic acid methyl ester,环己甲酸甲酯,Methyl hexahydrobenzoate |
Others; Endogenous Metabolite | Metabolism; Others |
Methyl cyclohexanecarboxylate (Methyl hexahydrobenzoate) 是一种内源性代谢物,用作化学合成的原料。环己烷羧酸甲酯是一种具有浆果味、酯味和水果味的调味成分。 | |||
TN7205 |
Methyl 5,6-dibromo-1H-indole-3-carboxylate
5,6-Dibromo-1H-indole-3-carboxylic acid methyl ester |
Others | Others |
Methyl 5,6-dibromo-1H-indole-3-carboxylate (5,6-Dibromo-1H-indole-3-carboxylic acid methyl ester) 是一种海洋来源的天然产物,存在于Smenospongia sp.。 | |||
T9513 |
Methyl 3-phenylpropanoate
3-Phenylpropionic acid methyl ester,3-苯丙酸甲酯 |
Endogenous Metabolite | Metabolism |
Methyl 3-phenylpropanoate (3-Phenylpropionic acid methyl ester) 是内源性代谢产物的一种。 | |||
T3239 |
Geranyl Tiglate
Geranium oil,tiglic acid geranyl ester,洋绣球,天竺葵油 |
Others | Others |
Geranyl Tiglate (tiglic acid geranyl ester) 是最重要的天然香料之一。 | |||
T2784 |
Ethyl Orsellinate
苷色酸乙酯,山梨酸乙酯,Orsellinic acid ethyl ester |
Others; Antibacterial | Microbiology/Virology; Others |
Ethyl Orsellinate (Orsellinic acid ethyl ester) 是地衣代谢产物,抑制A.salina 的细胞毒性活性,IC50为 495 μM。它是 lecanoric acid 的衍生物,具有抗增殖和抗肿瘤活性。 | |||
T3729 |
Ethyl gallate
Nipagallin A,Phyllemblin,gallic acid ethyl ester,没食子酸乙酯 |
MMP; NF-κB; Akt; Antibacterial | Cytoskeletal Signaling; Microbiology/Virology; NF-κB; PI3K/Akt/mTOR signaling; Proteases/Proteasome |
Ethyl gallate (gallic acid ethyl ester) 是一种非类黄酮酚过氧化氢清除剂。 | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03353 |
CEL Protein, Mouse, Recombinant (His)
1810036E18Rik,carboxyl ester lipase,BAL |
Mouse | Baculovirus Insect Cells |
CEL-maturity onset diabetes of the young (MODY), diabetes with pancreatic lipomatosis and exocrine dysfunction, is due to dominant frameshift mutations in the acinar cell carboxyl ester lipase gene (CEL). Bile-salt activated carboxylic ester lipase (CEL) is a major triglyceride, cholesterol ester and vitamin ester hydrolytic enzyme contained within pancreatic and lactating mammary gland secretions. Carboxyl ester lipase is a digestive pancreatic enzyme encoded by the CEL gene. Mutations in CEL c... | |||
TMPH-03323 |
LIPA Protein, Rat, Recombinant (His)
Lysosomal acid lipase/cholesteryl ester hy... |
Rat | E. coli |
Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol. LIPA Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 48.6 kDa and the accession number is Q64194. | |||
TMPH-01626 |
LIPA Protein, Human, Recombinant (GST)
Lysosomal acid lipase/cholesteryl ester hy... |
Human | E. coli |
Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol. LIPA Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 70.0 kDa and the accession number is P38571. | |||
TMPH-01625 |
LIPA Protein, Human, Recombinant (His)
Cholesteryl esterase,Lysosomal acid lipase... |
Human | P. pastoris (Yeast) |
Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol. LIPA Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 45.0 kDa and the accession number is P38571. | |||
TMPH-00711 |
BioH Protein, E. coli, Recombinant (His & Myc)
bioB,Carboxylesterase BioH,Biotin synthesis protein... |
E. coli | E. coli |
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. E.coli employs a methylation and demethylation strategy to allow elongation of a temporarily disguised malonate moiety to a pimelate moiety by the fatty acid synthetic enzymes. BioH shows a preference for short chain fatty acid esters (acyl c... | |||
TMPH-03448 |
EHT1 Protein, S. cerevisiae, Recombinant (His)
EHT1,Ethanol hexanoyl transferase 1,Alcohol O-acetyltransfer... |
Saccharomyces cerevisiae | E. coli |
Displays enzymatic activity both for medium-chain fatty acid (MCFA) ethyl ester synthesis and hydrolysis (esterase activity). MCFA are toxic for yeast and this enzyme could thus be involved in their detoxification by esterification. EHT1 Protein, S. cerevisiae, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 57.3 kDa and the accession number is P38295. | |||
TMPH-03376 |
SULT1A1 Protein, Rat, Recombinant (His & Myc & SUMO)
Sulfokinase,Aryl sulfotransferase IV,Phenol sulfotransferase... |
Rat | E. coli |
SULT1A1 Protein, Rat, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10XHis-SUMO and C-Myc tag. The predicted molecular weight is 53.9 kDa and the accession number is P17988. | |||
TMPH-02032 |
GPRC5A Protein, Human, Recombinant (GST)
G-protein coupled receptor family C group 5 member A,GPRC5A,... |
Human | E. coli |
Orphan receptor. Could be involved in modulating differentiation and maintaining homeostasis of epithelial cells. This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G-protein signaling pathways. Functions as a negative modulator of EGFR signaling. May act as a lung tumor suppressor. GPRC5A Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 37.0 kDa and the accession number i... | |||
TMPY-01776 |
Carboxylesterase 2/CES2 Protein, Human, Recombinant (His)
carboxylesterase 2,CES2A1,CE-2,PCE-2,iCE |
Human | HEK293 Cells |
Carboxylesterase 2/CES2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60.4 kDa and the accession number is O00748-1. | |||
TMPY-01693 |
Butyrylcholinesterase Protein, Human, Recombinant (His)
CHE1,E1,butyrylcholinesterase,CHE2 |
Human | HEK293 Cells |
Butyrylcholinesterase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.5 kDa and the accession number is P06276. | |||
TMPY-04189 |
Influenza A H15N2 (A/Australian shelduck/Western Australia/1756/1983) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H15N2 | HEK293 Cells |
Influenza A H15N2 (A/Australian shelduck/Western Australia/1756/1983) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is Q2FCC6. | |||
TMPJ-00459 |
Esterase D Protein, Human, Recombinant (His)
FGH,Methylumbelliferyl-Acetate Deacetylase,ESD,S-Formylgluta... |
Human | E. coli |
Human Esterase D is a cytoplasmic serine hydrolase that belongs to the esterase D family. Esterase D is involved in the detoxification of formaldehyde. Esterase D plays a part in a variety of substrates, including O-acetylated sialic acids, which may involves in the recycling of sialic acids. Esterase D is used as a genetic marker for retinoblastoma and Wilson’s disease. | |||
TMPH-03234 |
Acetylcholinesterase Protein, Rat, Recombinant (His)
AChE,EC:3.1.1.7 |
Rat | E. coli |
Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Acetylcholinesterase Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 68.9 kDa and the accession number is P37136. | |||
TMPH-03659 |
Vaccinia virus (strain Western Reserve) OPG094 Protein (His)
Protein F1,Myristoylated protein G9,Entry-fusion complex pro... |
VACV | P. pastoris (Yeast) |
Envelope protein part of the entry-fusion complex responsible for the virus membrane fusion with host cell membrane during virus entry. Also plays a role in cell-cell fusion (syncytium formation). Vaccinia virus (strain Western Reserve) OPG094 Protein (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 37.8 kDa and the accession number is P07611. | |||
TMPH-03657 |
Vaccinia virus (strain Western Reserve) OPG057 Protein (His & Myc)
p37K,OPG057,37 kDa protein,Envelope phospholipase OPG057,Env... |
VACV | E. coli |
Major envelope protein that plays a role in the biogenesis of the viral double membrane and in egress of virus from the host cell. Produces the wrapped form of virus that is required for cell-to-cell spread. Acts as a lipase with broad specificity including phospholipase C, phospholipase A, and triacylglycerol lipase activities. Vaccinia virus (strain Western Reserve) OPG057 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight ... | |||
TMPY-05673 |
Human coronavirus (HCoV-OC43) Hemagglutinin esterase Protein (His)
|
HCoV-OC43 | HEK293 Cells |
Human coronavirus (HCoV-OC43) Hemagglutinin esterase Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44 kDa and the accession number is A0A1L7H9D0. | |||
TMPH-03675 |
Vaccinia virus (strain Western Reserve) L1 Protein (E. coli, His)
Entry-fusion complex associated protein OPG095,EFC-associate... |
VACV | E. coli |
Envelope protein which probably plays a role in virus entry into the host cell. Is probably involved in the virus attachment to the host cell surface and associates with the entry/fusion complex (EFC). Needed for fusion and penetration of the virus core into host cell. Vaccinia virus (strain Western Reserve) L1 Protein (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 24.8 kDa and the accession number is P07612. | |||
TMPH-03661 |
Vaccinia virus (strain Western Reserve) OPG154 Protein (His & Myc)
OPG154,Protein OPG154 |
VACV | E. coli |
Structural protein involved in the envelopment of mature virion (MV) to form the wrapped virion (WV). The wrapping consists of the addition of Golgi membranes to the mature virion. Participates in mature virion (MV) movement within the infected cell. May play an indirect role in MV-cell fusion. Vaccinia virus (strain Western Reserve) OPG154 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.6 kDa and the accession numbe... | |||
TMPH-03668 |
Vaccinia virus (strain Western Reserve) OPG190 Protein (E. coli, His)
OPG190,Plaque-size/host range protein,Protein OPG190 |
VACV | E. coli |
Plays a role in the dissolution of the outermost membrane of extracellular enveloped virions (EV) to allow virion entry into host cells. Participates also in wrapping mature virions (MV) to form enveloped virions (EV). Vaccinia virus (strain Western Reserve) OPG190 Protein (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33.2 kDa and the accession number is Q01227. | |||
TMPY-01690 |
Carboxylesterase 2/CES2 Protein, Mouse, Recombinant (His)
carboxylesterase 2,ces2A3 |
Mouse | HEK293 Cells |
Carboxylesterase 2/CES2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60.4 kDa and the accession number is Q91WG0. | |||
TMPH-00232 |
Bovine coronavirus (strain Mebus) Hemagglutinin-esterase Protein (His)
Hemagglutinin-esterase,E3 glycoprotein,HE,HE protei... |
Bovine | P. pastoris (Yeast) |
Bovine coronavirus (strain Mebus) Hemagglutinin-esterase Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 47.7 kDa and the accession number is P15776. | |||
TMPH-03671 |
Vaccinia virus (strain Western Reserve) K3 Protein (His)
Protein K2,Protein K3 |
VACV | P. pastoris (Yeast) |
Viral mimic of eIF-2-alpha that acts as a pseudosubstrate for EIF2AK2/PKR kinase. Inhibits therefore eIF-2-alpha phosphorylation by host EIF2AK2/PKR kinase and prevents protein synthesis shutoff. Vaccinia virus (strain Western Reserve) K3 Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 12.6 kDa and the accession number is P18378. | |||
TMPH-01141 |
Human coronavirus HKU1 (isolate N2) Hemagglutinin-esterase (His)
HE,E3 glycoprotein,Hemagglutinin-esterase |
HCoV-HKU1 | E. coli |
Human coronavirus HKU1 (isolate N2) Hemagglutinin-esterase (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 45.9 kDa and the accession number is Q14EB1. | |||
TMPY-01742 |
Acetylcholinesterase Protein, Mouse, Recombinant (His)
Acre,Chrne,acetylcholinesterase (Yt blood group) |
Mouse | HEK293 Cells |
Acetylcholinesterase, also known as ACHE, is an enzyme that degrades (through its hydrolytic activity) the neurotransmitter acetylcholine, producing choline and an acetate group. Acetylcholinesterase plays a crucial role in nerve impulse transmission at cholinergic synapses by rapid hydrolysis of the neurotransmitter acetylcholine (ACh). ACHE appears to be a potential therapeutic target at muscle injuries including organophosphate myopathy. It is an externally oriented membrane-bound enzyme and ... | |||
TMPH-00571 |
ACP phosphodiesterase Protein, E. coli, Recombinant (His & Myc)
yajB,acpH,Acyl carrier protein phosphodiesterase |
E. coli | E. coli |
Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP. | |||
TMPH-00482 |
Arginine esterase Protein, Canine, Recombinant (His & SUMO)
|
Canine | E. coli |
Arginine esterase Protein, Canine, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-03669 |
Vaccinia virus (strain Western Reserve) OPG190 Protein (His)
OPG190,Plaque-size/host range protein,Protein OPG190 |
VACV | P. pastoris (Yeast) |
Plays a role in the dissolution of the outermost membrane of extracellular enveloped virions (EV) to allow virion entry into host cells. Participates also in wrapping mature virions (MV) to form enveloped virions (EV). Vaccinia virus (strain Western Reserve) OPG190 Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 31.1 kDa and the accession number is Q01227. | |||
TMPH-03654 |
Vaccinia virus (strain Western Reserve) 3-beta-HSD Protein (His & Myc)
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase,OP... |
VACV | E. coli |
Catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. During viral infection, steroid production contributes to virulence by inhibiting the host inflammatory response. Vaccinia virus (strain Western Reserve) 3-beta-HSD Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted... | |||
TMPY-03250 |
Influenza A H15N2 (A/Australian shelduck/Western Australia/1756/1983) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H15N2 | Baculovirus Insect Cells |
Influenza A H15N2 (A/Australian shelduck/Western Australia/1756/1983) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59 kDa and the accession number is Q2FCC6. | |||
TMPY-01596 |
Butyrylcholinesterase Protein, Mouse, Recombinant (His)
C730038G20Rik,butyrylcholinesterase |
Mouse | HEK293 Cells |
Butyrylcholinesterase Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.7 kDa and the accession number is Q03311. | |||
TMPH-03672 |
Vaccinia virus (strain Western Reserve) K3 Protein (His & SUMO)
Protein K2,Protein K3 |
VACV | E. coli |
Viral mimic of eIF-2-alpha that acts as a pseudosubstrate for EIF2AK2/PKR kinase. Inhibits therefore eIF-2-alpha phosphorylation by host EIF2AK2/PKR kinase and prevents protein synthesis shutoff. Vaccinia virus (strain Western Reserve) K3 Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 26.6 kDa and the accession number is P18378. | |||
TMPH-03664 |
Vaccinia virus (strain Western Reserve) OPG161 Protein (His)
OPG161,Protein OPG161 |
VACV | P. pastoris (Yeast) |
Coordinates the incorporation of A36 into wrapped enveloped virion (EV) membranes and, subsequently, the production of actin tails. Therefore plays an essential role in efficient cell-to-cell spread of viral particles. Vaccinia virus (strain Western Reserve) OPG161 Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 16.2 kDa and the accession number is P68617. | |||
TMPH-03676 |
Vaccinia virus (strain Western Reserve) L1 Protein (His)
Entry-fusion complex associated protein OPG095,EFC-associate... |
VACV | P. pastoris (Yeast) |
Envelope protein which probably plays a role in virus entry into the host cell. Is probably involved in the virus attachment to the host cell surface and associates with the entry/fusion complex (EFC). Needed for fusion and penetration of the virus core into host cell. Vaccinia virus (strain Western Reserve) L1 Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 21.3 kDa and the accession number is P07612. | |||
TMPH-02562 |
CES1C Protein, Mouse, Recombinant (His & Myc)
Ces1c,Liver carboxylesterase N,Es1,Lung surfactant ... |
Mouse | HEK293 Cells |
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant. | |||
TMPH-02561 |
CES1C Protein, Mouse, Recombinant (GST)
Liver carboxylesterase N,Es1,Lung surfactant conver... |
Mouse | E. coli |
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant. | |||
TMPY-03330 |
BPHL Protein, Human, Recombinant (His)
biphenyl hydrolase-like (serine hydrolase),VACVASE,MCNAA,BPH... |
Human | E. coli |
BPHL is a member of the serine protease family. BPHL is expressed large quantities in liver and kidney and in minor quantities in heart, intestine and skeletal muscle. BPHL is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol. It catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir ... | |||
TMPH-02563 |
CES1C Protein, Mouse, Recombinant
Es1,PES-N,Liver carboxylesterase N,Carboxyleste... |
Mouse | E. coli |
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant. CES1C Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 58.6 kDa and the accession number is P23953. | |||
TMPH-02667 |
Galactosylceramidase Protein, Mouse, Recombinant
Galactocerebroside beta-galactosidase,Galactocerebrosidase,G... |
Mouse | E. coli |
Hydrolyzes the galactose ester bonds of glycolipids such as galactosylceramide and galactosylsphingosine. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon. | |||
TMPY-04406 |
Protein Kinase D2/PRKD2 Protein, Human, Recombinant (His & GST)
protein kinase D2,nPKC-D2,PKD2,HSPC187 |
Human | Baculovirus Insect Cells |
Serine/threonine-protein kinase D2, also known as PRKD2 and PKD2, is a cytoplasm and membrane protein that belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and PKD subfamily. PRKD2 / PKD2 is widely expressed. It contains one PH domain, two phorbol-ester/DAG-type zinc fingers and one protein kinase domain. PRKD2 / PKD2 is activated by DAG and phorbol esters. Phorbol-ester/DAG-type domains bind DAG, mediating translocation to membranes. Autophosphorylation of Ser-71 an... | |||
TMPY-02452 |
CMBL Protein, Human, Recombinant (His)
carboxymethylenebutenolidase homolog (Pseudomonas),JS-1 |
Human | E. coli |
Carboxymethylenebutenolidase (CMBL), also known as 4-carboxymethylenebut-2-en-4-olide lactonohydrolase, maleylacetate enol- lactonase, dienelactone hydrolase, and carboxymethylene butenolide hydrolase, is a hydrolase specially belonging to the family of hydrolases. It maily acts on carboxylic ester bonds. CMBL is a human homolog of Pseudomonas dienelactone hydrolase involved in the bacterial halocatechol degradation pathway. The ubiquitous expression of human CMBL gene transcript in various tiss... | |||
TMPY-02952 |
SIAE Protein, Human, Recombinant (His)
CSE-C,AIS6,CSEC,LSE,YSG2,sialic acid acetylesterase |
Human | Baculovirus Insect Cells |
Sialate O-acetylesterase belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. It is widely expressed with high expression in the testis, prostate, and colon. The systematic name of this enzyme class is N-acyl-O-acetylneuraminate O-acetylhydrolase. Other names in common use include N-acetylneuraminate acetyltransferase, sialate 9(4)-O-acetylesterase, and sialidase. Sialate O-acetylesterase catalyzes the removal of O-acetyl ester groups from position 9 of the p... | |||
TMPH-02605 |
Complement C4-B Protein, Mouse, Recombinant (His)
C3 and PZP-like alpha-2-macroglobulin domain-containing prot... |
Mouse | E. coli |
Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. Catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens. | |||
TMPY-04456 |
PKC nu Protein, Human, Recombinant (GST)
PRKCN,nPKC-NU,PKC-NU,PKD3,EPK2,protein kinase D3 |
Human | Baculovirus Insect Cells |
Serine/threonine-protein kinase D3, also known as Protein kinase C nu type, Protein kinase EPK2, PRKD3, EPK2 and PRKCN, is a cytoplasm and membrane protein that belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and PKD subfamily. PRKD3 / PRKCN contains one PH domain, two phorbol-ester/DAG-type zinc fingers and one protein kinase domain. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second ... | |||
TMPJ-01138 |
UBE2S Protein, Human, Recombinant (GST)
UBE2S,Ubiquitin-Conjugating Enzyme E2-24 kDa,E2-EPF,E2EPF,Ub... |
Human | E. coli |
Ubiquitin-Conjugating Enzyme E2 S (UBE2S) is a member of the Ubiquitin-Conjugating Enzyme family. UBE2S interacts with CDC20, FZR1/CDH1 and VHL. UBE2S can form a thiol ester linkage with Ubiquitin in an Ubiquitin Activating Enzyme-Dependent manner, a characteristic property of Ubiquitin Carrier Proteins. UBE2S acts as an essential factor of the Anaphase Promoting Complex/Cyclosome, a cell cycle-regulated Ubiquitin ligase that controls progression through mitosis. UBE2S is also involved in ubiqui... | |||
TMPY-03182 |
PLRP2 Protein, Human, Recombinant (His)
PLRP2,pancreatic lipase-related protein 2 |
Human | Baculovirus Insect Cells |
Galactolipase, also known as PNLIPRP2, is a lipase with broad substrate specificity. It can hydrolyze both phospholipids and galactolipids. Galactolipase acts preferentially on monoglycerides, phospholipids and galactolipids. It also hydrolyses milk fat with a lower catalytic efficiency. The expressed galactolipase shows a lipolytic activity that is, however, only marginally dependent on the presence of colipase. The lipolytic activity of pancreatic extracts and human pancreatic juice on Labraso... | |||
TMPY-03216 |
GMF beta/GMFB Protein, Human, Recombinant
GMF β/GMFB,glia maturation factor, β,glia maturation factor,... |
Human | E. coli |
GMFB is a nerve growth factor which belongs to the actin-binding proteins ADF family, GMF subfamily. GMFB is involved in nervous system development, angiogenesis and immune function. It is especially crucial for the nervous system. GMFB causes brain cell differentiation, stimulates neural regeneration and inhibits tumor cell proliferation. It contains 1 ADF-H domain and is phosphorylated after phorbol ester stimulation. GMFB overexpression in astrocytes results in the increase of BDNF production... | |||
TMPH-03740 |
DCL Protein, Bacillus subtilis, Recombinant (His)
DCL,D-alanine--poly(phosphoribitol) ligase subunit 1,dltA,DA... |
Bacillus subtilis | E. coli |
Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the... | |||
TMPJ-00024 |
GMF beta/GMFB Protein, Human, Recombinant (His)
GMF-β,GMF-beta,GMFB,Glia maturation factor beta,Glia maturat... |
Human | E. coli |
Glia maturation factor beta (GMFB) contains a ADF-H domain,which is a member of the actin-binding proteins ADF family, GMF subfamily. It is a nerve growth factor implicated in nervous system development, angiogenesis and immune function. GMFB causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells. It is phosphorylated after phorbol ester stimulation, and is crucial for the nervous system. GMFB overexpression in astrocytes results... | |||
TMPY-02453 |
CROT Protein, Human, Recombinant (474 Leu/Val, His)
carnitine O-octanoyltransferase,COT |
Human | Baculovirus Insect Cells |
Carnitine octanoyltransferase (CROT or COT), also known as octanoyl-CoA: L-carnitine O-octanoyltransferase, medium-chain/long-chain carnitine acyltransferase, and carnitine medium-chain acyltransferase, is a carnitine acyltransferase belonging to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups that catalyzes the reversible transfer of fatty acyl groups between CoA and carnitine. Carnitine octanoyltransferase (CROT or COT) facilitate... | |||
TMPJ-00553 |
Lp-PLA2/PLA2G7 Protein, Human, Recombinant (aa 22-441, His)
PAF Acetylhydrolase,LDL-Associated Phospholipase A2,LDL-PLA(... |
Human | HEK293 Cells |
Platelet-Activating Factor Acetylhydrolase (PAFAH) is a secreted enzyme which belongs to the AB hydrolase superfamily and Lipase family and catalyzes the degradation of platelet-activating factor to biologically inactive products. PAFAH is produced by inflammatory cells and hydrolyzes oxidised phospholipids in LDL. PAFAH has been implicated in the development of atherosclerosis and has also been identified as a marker for cardiac disease. PAFAH might have a major physiologic effect in the presen... | |||
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Cat. No. | Product Name | Target | Signaling Pathways |
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TMIJ-0413 |
Phthalic acid, bis-propyl ester-d4
|
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Phthalic acid, bis-propyl ester-d4 是 Phthalic acid, bis-propyl ester 的氘代化合物。Phthalic acid, bis-propyl ester 的 CAS 号为 131-16-8。 | |||
TMIJ-0412 |
Phthalic acid, bis-isobutyl ester-d4
|
||
Phthalic acid, bis-isobutyl ester-d4 是 Phthalic acid, bis-isobutyl ester 的氘代化合物。Phthalic acid, bis-isobutyl ester 的 CAS 号为 84-69-5。Dibutyl phthalate 是一种用于大多数塑料的增塑剂,存在于水、空气、土壤、植物和动物中。长期接触可能会产生一些不利影响。 | |||
TMIJ-0368 |
Phthalic acid, bis-2-n-butoxyethyl ester-d4
|
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Phthalic acid, bis-2-n-butoxyethyl ester-d4 是 Phthalic acid, bis-2-n-butoxyethyl ester 的氘代化合物。Phthalic acid, bis-2-n-butoxyethyl ester 的 CAS 号为 117-83-9。 | |||
TMIJ-0367 |
Phthalic acid, bis-4-methyl-2-pentyl ester-d4
|
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Phthalic acid, bis-4-methyl-2-pentyl ester-d4 是 Phthalic acid, bis-4-methyl-2-pentyl ester 的氘代化合物。Phthalic acid, bis-4-methyl-2-pentyl ester 的 CAS 号为 146-50-9。 | |||
T19416 |
Medroxyprogesterone acetate D3
MPA D3,Medroxyprogesterone 17-acetate D3 |
Others | Others |
Medroxyprogesterone acetate D3 is deuterium labeled Medroxyprogesterone acetate. Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors. | |||
TMID-0133 |
Medroxyprogesterone-d3
|
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Medroxyprogesterone-d3 是 Medroxyprogesterone 的氘代化合物。Medroxyprogesterone 的 CAS 号为 520-85-4。Medroxyprogesterone 是一种合成的人孕酮变体,是孕酮受体激动剂,用于治疗肾癌。在兽医实践中用作发情调节剂。 | |||
TMIH-0324 |
Medroxyprogesterone 17-Acetate-d3
|
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Medroxyprogesterone 17-Acetate-d3 是 Medroxyprogesterone 17-Acetate 的氘代化合物。Medroxyprogesterone 17-Acetate 的 CAS 号为 71-58-9。Medroxyprogesterone acetate 是广泛使用的合成类固醇,与雄激素,孕酮及糖皮质激素受体均有作用。 | |||
TMID-0226 |
Cholesterol-d4
|
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Cholesterol-d4 是 Cholesterol 的氘代化合物。Cholesterol 的 CAS 号为 57-88-5。Cholesterol 是哺乳动物中的主要固醇,占质膜结构成分的 20-25%。Cholesterol 在确定膜的流动性和渗透性特征以及转运蛋白和信号蛋白的功能中起着重要作用。Cholesterol 还是内源性雌激素相关受体 α 激动剂。 | |||
TMIH-0456 |
Progesterone-d9 (isomer)
17α-progesterone-d9 |
||
Progesterone-d9 (isomer) 是 Progesterone (isomer) 的氘代化合物。Progesterone (isomer) 的 CAS 号为 2000-66-0。 | |||
TMIH-0455 |
Progesterone-d9
|
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Progesterone-d9 是 Progesterone 的氘代化合物。 | |||
TMID-0223 |
Cholesterol-d7
|
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Cholesterol-d7 是 Cholesterol 的氘代化合物。Cholesterol 的 CAS 号为 57-88-5。Cholesterol 是哺乳动物中的主要固醇,占质膜结构成分的 20-25%。Cholesterol 在确定膜的流动性和渗透性特征以及转运蛋白和信号蛋白的功能中起着重要作用。Cholesterol 还是内源性雌激素相关受体 α 激动剂。 | |||
TMID-0224 |
Cholesterol-d6
|
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Cholesterol-d6 是 Cholesterol 的氘代化合物。Cholesterol 的 CAS 号为 57-88-5。Cholesterol 是哺乳动物中的主要固醇,占质膜结构成分的 20-25%。Cholesterol 在确定膜的流动性和渗透性特征以及转运蛋白和信号蛋白的功能中起着重要作用。Cholesterol 还是内源性雌激素相关受体 α 激动剂。 | |||
TMID-0225 |
Cholesterol-d6-1
|
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Cholesterol-d6-1 是 Cholesterol 的氘代化合物。Cholesterol 的 CAS 号为 57-88-5。Cholesterol 是哺乳动物中的主要固醇,占质膜结构成分的 20-25%。Cholesterol 在确定膜的流动性和渗透性特征以及转运蛋白和信号蛋白的功能中起着重要作用。Cholesterol 还是内源性雌激素相关受体 α 激动剂。 | |||
TMIH-0206 |
Dydrogesterone-d6
|
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Dydrogesterone-d6 是 Dydrogesterone 的氘代化合物。Dydrogesterone 的 CAS 号为 152-62-5。Dydrogesterone 是一种口服有效的孕激素,可作用于孕酮缺乏相关疾病。 | |||
TMIH-0026 |
17α-Hydroxyprogesterone-d8
|
||
17α-Hydroxyprogesterone-d8 是 17α-Hydroxyprogesterone 的氘代化合物。 | |||
TMIJ-0337 |
(24Rac)-Campesterol-d7
|
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(24Rac)-Campesterol-d7 是 (24Rac)-Campesterol 的氘代化合物。(24Rac)-Campesterol 的 CAS 号为 474-62-4。Campesterol是一种植物甾醇,具有降胆固醇和抗癌的活性。 | |||
TMID-0129 |
Megestrol-d5
|
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Megestrol-d5 是 Megestrol 的氘代化合物。Megestrol 的 CAS 号为 3562-63-8。 | |||
TMID-0128 |
Megestrol-d3
|
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Megestrol-d3 是 Megestrol 的氘代化合物。Megestrol 的 CAS 号为 3562-63-8。 | |||
TMIJ-0486 |
Diazinon-d10
|
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Diazinon-d10 是 Diazinon 的氘代化合物。Diazinon 的 CAS 号为 333-41-5。Diazinon是硫代磷酸酯, 是一种非系统性有机磷杀虫剂,用于防治蟑螂、银鱼、蚂蚁和跳蚤。 | |||
TMID-0086 |
Mycophenolate Mofetil-d4
|
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Mycophenolate Mofetil-d4 是 Mycophenolate Mofetil 的氘代化合物。Mycophenolate Mofetil 的 CAS 号为 128794-94-5。Mycophenolate mofetil 是 Mycophenolic acid 的吗啉乙酯前药。它通过抑制肌苷一磷酸脱氢酶抑制从头嘌呤合成,显示出选择性淋巴细胞抗增殖作用。 | |||
TMIJ-0208 |
Beclomethasone Dipropionate-d6
|
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Beclomethasone Dipropionate-d6 是 Beclomethasone Dipropionate 的氘代化合物。Beclomethasone Dipropionate 的 CAS 号为 5534-09-8。Betamethasone dipropionate是具有口服活性的糖皮质激素,具有抗炎和免疫抑制作用。它是Betamethasone 的前体药物,Betamethasone 是 LPS 诱导的炎症及 MMP 释放的抑制剂。 | |||
TMIJ-0204 |
Betamethasone-d10 Dipropionate
|
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Betamethasone-d10 Dipropionate 是 Betamethasone Dipropionate 的氘代化合物。Betamethasone Dipropionate 的 CAS 号为 5593-20-4。Betamethasone dipropionate 是糖皮质激素类固醇,具有免疫抑制、抗炎作用。 | |||
T70883 |
Moexipril-d5
|
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Moexipril-d5 intended for use as an internal standard for the quantification of moexipril by GC- or LC-MS. Moexipril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor moexiprilat. It is converted to moexiprilat in vivo by side chain ester hydrolysis. Moexipril inhibits ACE in a cell-free assay (IC50 = 2.7 µM for the rabbit enzyme). It also inhibits phosphodiesterase 4 (IC50s = 38, 160, and 230 µM for PDE4B2, PDE4A5 and PDE4D5, respectively). Moexipril (0.1-30 mg/kg per day) ... | |||
TMIJ-0398 |
rac 1,2-Bis-palmitoyl-3-chloropropanediol-d5
|
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rac 1,2-Bis-palmitoyl-3-chloropropanediol-d5 是 rac 1,2-Bis-palmitoyl-3-chloropropanediol 的氘代化合物。rac 1,2-Bis-palmitoyl-3-chloropropanediol 的 CAS 号为 51930-97-3。 |