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Prostaglandin F2α isopropyl ester
还可以产品编号 T38196Cas号 53764-90-2
别名 Prostaglandin F2α isopropyl ester
PGF2α isopropyl ester is an ester prodrug of PGF2α with enhanced lipid solubility. Due to better membrane penetration, PGF2α isopropyl ester is more suitable than PGF2α or PGF2α tromethamine salt for topical application in studies on intraocular pressure. The ester functionality is readily hydrolyzed in vivo to release the active compound PGF2α. When administered topically to the eyes of cynomolgus monkeys, a 5 μg dose reduces intraocular pressure by 68% after the fourth day of treatment.
Prostaglandin F2α isopropyl ester
还可以产品编号 T38196 别名 Prostaglandin F2α isopropyl esterCas号 53764-90-2
PGF2α isopropyl ester is an ester prodrug of PGF2α with enhanced lipid solubility. Due to better membrane penetration, PGF2α isopropyl ester is more suitable than PGF2α or PGF2α tromethamine salt for topical application in studies on intraocular pressure. The ester functionality is readily hydrolyzed in vivo to release the active compound PGF2α. When administered topically to the eyes of cynomolgus monkeys, a 5 μg dose reduces intraocular pressure by 68% after the fourth day of treatment.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 1 mg | ¥ 1,240 | 35日内发货 | |
| 5 mg | ¥ 5,470 | 35日内发货 | |
| 10 mg | ¥ 9,690 | 35日内发货 |
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| 产品描述 | PGF2α isopropyl ester is an ester prodrug of PGF2α with enhanced lipid solubility. Due to better membrane penetration, PGF2α isopropyl ester is more suitable than PGF2α or PGF2α tromethamine salt for topical application in studies on intraocular pressure. The ester functionality is readily hydrolyzed in vivo to release the active compound PGF2α. When administered topically to the eyes of cynomolgus monkeys, a 5 μg dose reduces intraocular pressure by 68% after the fourth day of treatment. |
| 别名 | Prostaglandin F2α isopropyl ester |
| 分子量 | 396.568 |
| 分子式 | C23H40O5 |
| CAS No. | 53764-90-2 |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度信息 | DMSO: >50 mg/mL DMF: >30 mg/mL Ethanol: >50 mg/mL PBS (pH 7.2): <50 μg/mL |
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