购物车
- 全部删除
您的购物车当前为空
SCH 42495
还可以产品编号 T12641LCas号 136511-43-8
SCH 42495 is an orally active neutral metalloendopeptidase inhibitor. SCH 42495 is the orally active ethyl ester prodrug of SCH 42354.
SCH 42495
还可以产品编号 T12641LCas号 136511-43-8
SCH 42495 is an orally active neutral metalloendopeptidase inhibitor. SCH 42495 is the orally active ethyl ester prodrug of SCH 42354.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 mg | ¥ 10,600 | 6-8周 | |
| 50 mg | ¥ 13,800 | 6-8周 | |
| 100 mg | ¥ 17,500 | 6-8周 |
大包装 & 定制
加入购物车
实验操作小课堂
查看更多 联系我们获取更多批次信息
资源下载
产品介绍
生物活性
化学信息
| 产品描述 | SCH 42495 is an orally active neutral metalloendopeptidase inhibitor. SCH 42495 is the orally active ethyl ester prodrug of SCH 42354. |
| 体外活性 | SCH 42354 inhibits the hydrolysis of leu-enkephalin and ANF (IC50: 8.3 and 10.0 nM, respectively) [1]. |
| 体内活性 | SCH 42495 (oral doses of 1, 3, or 10 mg/kg) produces significant reductions in blood pressure in DOCA-N a hypertensive rats of 22±6, 43±7, and 62±12 mm Hg, respectively. SCH 42495 (30 mg/kg; oral gavage; twice daily) leads to a significant reduction in pulmonary vascular remodeling and ventricular hypertrophy in hypoxic rats after 10 days. Treatment with SCH 42495 (30 mg/kg; oral gavage; twice daily) resulting in a decrease in cardiovascular remodeling secondary to chronic hypoxia in rats [1][2]. |
| 分子量 | 411.58 |
| 分子式 | C20H29NO4S2 |
| CAS No. | 136511-43-8 |
| 密度 | 1.158 g/cm3 (Predicted) |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
计算器
体内实验配液计算器
请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
剂量转换
对于不同动物的给药剂量换算，您也可以参考 更多
评论列表
预览
Related Tags: buy SCH 42495 | purchase SCH 42495 | SCH 42495 cost | order SCH 42495 | SCH 42495 chemical structure | SCH 42495 in vivo | SCH 42495 in vitro | SCH 42495 formula | SCH 42495 molecular weight
嗨！很高兴为您提供帮助！
评论内容