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Kalii Dehydrographolidi Succinas (Dehydroandrographolide Succinate Potasium Salt) 从中药穿心莲中提取得到,具有免疫刺激、抗感染和抗炎作用,对病毒性肺炎和病毒性上呼吸道感染具有潜在的研究价值。
Kalii Dehydrographolidi Succinas (Dehydroandrographolide Succinate Potasium Salt) 从中药穿心莲中提取得到,具有免疫刺激、抗感染和抗炎作用,对病毒性肺炎和病毒性上呼吸道感染具有潜在的研究价值。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥ 178 | 现货 | |
10 mg | ¥ 247 | 现货 | |
25 mg | ¥ 465 | 现货 | |
50 mg | ¥ 678 | 现货 | |
100 mg | ¥ 997 | 现货 | |
200 mg | ¥ 1,470 | 现货 | |
500 mg | ¥ 2,490 | 现货 |
产品描述 | Kalii Dehydrographolidi Succinas (Dehydroandrographolide Succinate Potasium Salt) is a natural compound with anti-virus infection activity. |
激酶实验 | In vitro kinase assay is based on a filter binding assay, using the recombinant GST-fused kinase domains expressed in baculovirus and purified over glutathione-sepharose, γ-[33P]ATP as the phosphate donor, and poly(Glu:Tyr 4:1) peptide as the acceptor. Each GST-fused kinase is incubated under optimized buffer conditions [20 mM Tris-HCl buffer (pH 7.5), 1-3 mM MnCl2, 3-10 mM MgCl2, 3-8 μg/mL poly(Glu:Tyr 4:1), 0.25 mg/mL polyethylene glycol 20000, 8 μM ATP, 10 μM sodium vanadate, 1 mM DTT] and 0.2 μCi γ-33P ATP in a total volume of 30 μL in the presence or absence of a test substance for 10 min at ambient temperature. The reaction is stopped by adding 10 mL of 250 mM EDTA. Using a 384-well filter system, half the volume is transferred onto an Immobilon-polyvinylidene difluoride membrane. The membrane is then washed extensively and dried, and scintillation counting is performed. IC50s for compounds are calculated by linear regression analysis of the percentage inhibition[1]. |
别名 | 穿琥宁, Dehydroandrographolide Succinate Potasium Salt, Ddhads |
分子量 | 570.67 |
分子式 | C28H35KO10 |
CAS No. | 76958-99-1 |
Smiles | C[C@]12[C@@](CCC([C@H]2/C=C/C3=CCOC3=O)=C)([H])[C@@](C)([C@@H](CC1)OC(CCC([O-])=O)=O)COC(CCC(O)=O)=O.[K+] |
密度 | no data available |
存储 | keep away from direct sunlight,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
溶解度信息 | DMSO: 5.7 mg/mL (10 mM), Sonication is recommended. | ||||||||||||||||||||
溶液配制表 | |||||||||||||||||||||
DMSO
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