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Targets Recommended: Cytokine release PDE

146

抑制剂 & 化合物

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化合物库

286

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同位素标记化合物

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Cat. No. Product Name
L3600 细胞因子抑制剂库

604 compounds
604 个与细胞因子紧密相关的化合物集合,是高通量、高内涵筛选的良好载体;
L5400 抗心血管疾病化合物库

1408 compounds
1408 种心血管疾病相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L4700 免疫/炎症分子化合物库

4720 compounds
4720 种具有抗炎症活性的化合物的特有集合,可用于高通量筛选和高内涵筛选;
L6720 抗COVID-19中药单体库

1147 compounds
根据抗新冠肺炎疫情过程中应用于临床治疗的中药方剂,收集了1147 种相关中药来源的单体化合物,可用于高通量和高内涵筛选,是抗新冠病毒药物研发的良好工具;

化合物库

细胞因子抑制剂库
Cat.No: L3600
Compounds: 604
抗心血管疾病化合物库
Cat.No: L5400
Compounds: 1408
免疫/炎症分子化合物库
Cat.No: L4700
Compounds: 4720
抗COVID-19中药单体库
Cat.No: L6720
Compounds: 1147
Cat. No. Product Name Target Signaling Pathways
T5033 Olprinone

奥普力农,Loprinone

PDE Metabolism
Olprinone (Loprinone) 是一种有效的磷酸二酯酶(PDE) 3抑制剂,对 PDE1,PDE2,PDE3,PDE4 的IC50分别为 150、100、0.35 和 14 μM,具有抗炎活性。它具有正性肌力和血管扩张作用,可用于心力衰竭的研究。
T7860 SM-324405

SM 324405

TLR Immunology/Inflammation
SM-324405 是TLR7的激动剂,EC50 为 50 nM,对人和大鼠 TLR7 的 pEC50值分别为 7.3 和 6.6,可用于过敏性疾病的免疫治疗研究。
T16111 ML604086

CCR Immunology/Inflammation; Microbiology/Virology
ML604086 是选择性CCR8抑制剂,抑制循环T 细胞上 CCL1 与 CCR8 结合,还抑制 CCL1 介导的趋化性并提高细胞内 Ca2 浓度。
T1421 Aceclofenac

醋氯芬酸,Preservex,Airtal

COX Immunology/Inflammation; Neuroscience
Aceclofenac (Preservex) 是一种可口服的非甾体抗炎药,可用于缓解疼痛、骨关节炎、强直性脊柱炎、类风湿性关节炎的研究。
T15784 LP99

Epigenetic Reader Domain Chromatin/Epigenetic
LP99 是一种表观遗传探针,可破坏 BRD7 和 BRD9 与细胞中染色质的结合。它是一种选择性的 BRD7 和 BRD9 溴结构域抑制剂,对 BRD9 的 Kd 为 99 nM。
T15102 Dexamethasone palmitate

地塞米松棕榈酸酯,DXP

Glucocorticoid Receptor Endocrinology/Hormones
Dexamethasone palmitate (DXP) (DXP) 是 Dexamethasone 的前药。Dexamethasone 是糖皮质激素受体激动剂。与Dexamethasone 相比, DXP 对糖皮质激素受体的亲和力低 47 倍。DXP 显示出抗炎活性。
T13951 UCB-9260

TNF Apoptosis
UCB-9260 是口服活性小分子,通过稳定三聚体的不对称形式抑制肿瘤坏死因子信号传导。它对肿瘤坏死因子的选择性高于其他超家族成员,并与肿瘤坏死因子结合,其Kd 值为 13 nM。
T0498 Salsalate

Disalicylic acid,Salicylsalicylic acid,Sasapyrine,NSC-49171,双水杨酸酯

Reactive Oxygen Species; COX Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
Salsalate (Sasapyrine) 是一种有效的抗风湿药物,是一种非乙酰化水杨酸盐,可以绕过胃的吸收,也可以避免环氧合酶的抑制。它具有抗炎活性,降低血糖水平、胰岛素抵抗和细胞因子表达,可用于研究 2 型糖尿病。
T1902 BAY 11-7082

BAY 11-7821

Apoptosis; Others; IκB/IKK; DUB; Autophagy Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; NF-κB; Others; Ubiquitination
BAY 11-7082 (BAY 11-7821) 是一种 NF-κB 抑制剂,可抑制 TNFα 诱导的 IκBα 磷酸化 (IC50=10 μM)。BAY 11-7082 也是一种泛素特异性蛋白酶 USP7 和 USP21 的抑制剂 (IC50=0.19/0.96 μM)。
T27695 JTE-607

JTE-607 dihydrochloride,JTE-607 HCl,甲氧番荔枝碱

Cysteine Protease Proteases/Proteasome
JTE-607 HCl 是高选择性的炎性细胞因子合成抑制剂,可保护小鼠免受内毒素休克。它作用于 LPS 刺激的人 PBMC,抑制TNF-α(IC50:11 nM)、IL-1β(IC50:5.9 nM)、IL-6(IC50:8.8 nM)、IL-8(IC50:7.3 nM)和IL-10(IC50:9.1 nM)。
T2036 6-OAU

GTPL5846

GPR Endocrinology/Hormones; GPCR/G Protein
6-OAU (GTPL5846) 是 GPR84 的替代激动剂,在 Gqi5 嵌合体存在的情况下,在 HEK293 细胞中激活人 GPR84,在 PI 测定中 EC50 为 105 nM。
T4602 Hydrocortisone hemisuccinate

Hydrocortisone 21-he,氢化可的松琥珀酸酯,hydrocortisone 21-hemisuccinate*free acid,Hydrocortisone 21-hemisuccinate

Glucocorticoid Receptor; Others; Interleukin Endocrinology/Hormones; Immunology/Inflammation; Others
Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) 是糖皮质激素, 是口服有活性的甾体抗炎剂。它能够降低IL-6(IC50:6.7 μM)、IL-3(IC50:21.4 μM)的生物活性,可用于研究溃疡性结肠炎。
T4122 TAPI-1 trifluoroacetate (163847-77-6(free base))

MMP Proteases/Proteasome
TAPI-1 trifluoroacetate 是一种 ADAM17/TACE 抑制剂,可阻断细胞因子受体的脱落。
T8640 G6PDi-1

Dehydrogenase Metabolism
G6PDi-1 是一种有效的 G6PD 抑制剂。它消耗 NADPH 并减少炎性细胞因子的产生。
T6657 SB273005

Integrin Cytoskeletal Signaling
SB273005 是一种具有口服活性和高效性非肽整合素αvβ3 拮抗剂,抑制 αvβ3 和 αvβ5,可减少怀孕小鼠中 Th2 细胞和细胞因子 IL-10 的产生。
T77484 Atibuclimab

TNF Apoptosis
Atibuclimab 是一种靶向 CD14 的嵌合单克隆抗体,由小鼠可变区和人类 IgG4 Fc 区构成。Atibuclimab 可用于治疗肌萎缩侧索硬化症。Atibuclimab 可减少 LPS 诱导的病症,并对 LPS 诱导的促炎细胞因子释放有抑制作用,可延迟抗炎细胞因子可溶性 TNF 受体 I 型的释放,
T13171 TMN355

2-氯-N-[(9H-芴-9-氨基)羰基]-6-氟苯甲酰胺

Others Others
TMN355 是一种化学亲环素 A 抑制剂,能够抑制泡沫细胞形成和细胞因子分泌,可用于动脉粥样硬化的研究。
T80678 (S)-AK-242

(-)-Resatorvid,(S)-Resatorvid,AK-242 (S enantiomer),(-)-AK-242

Others Others
(S)-AK-242 ((S)-Resatorvid) 是一种细胞因子抑制剂,可用于治疗心脏病、自身免疫性疾病、炎症性疾病。
T24154 I942

I 942,I-942

cAMP GPCR/G Protein
I942 是一种新型且具有选择性的非环核苷酸 (NCN) EPAC1 激动剂,可激活交换蛋白调节人脐血管中的炎症基因表达,可抑制与心血管疾病相关的促炎细胞因子信号传导。
T5354 IRAK4-IN-7

CA-4948

IRAK Immunology/Inflammation; NF-κB
IRAK4-IN-7 (CA-4948) 是白介素 1 受体相关激酶 4 (IRAK4) 的选择性抑制剂,口服有活性。它可用于研究癌症以及炎症疾病。
T4078 SB 242235

SB-242235,SB242235

p38 MAPK; Autophagy Autophagy; MAPK
SB 242235 是一种有效的选择性 p38 MAP 激酶抑制剂,可能是细胞因子介导疾病的有效疗法,在人的软骨细胞中 IC50值为 1.0 μM。
T21339 Peramivir

RWJ270201,BCX 1812,BCX1812,RWJ 270201

Antiviral Immunology/Inflammation
Peramivir (BCX1812) 是一种高选择性的甲型和乙型流感神经氨酸酶抑制剂,具有抗病毒活性和抗细胞因子作用,可用于研究新型冠状病毒和流感病毒感染。
T37292 M62812

TLR Immunology/Inflammation
M62812是一种 TLR4抑制剂,可在 HEK239细胞中抑制 LPS 诱导的NF-κB 活化。
T11492 GSK2983559 free acid

Others; RIP kinase Apoptosis; NF-κB; Others
GSK2983559 free acid 是一种有效的特异性受体相互作用蛋白 2 (RIP2) 抑制剂。 GSK2983559 free acid 在阻断人类炎症性肠病外植体样品和体内的许多促炎细胞因子反应方面表现出优异的活性。
T67892 BTB09089

GPR65 agonist (BTB09089)

GPR; DNA DNA Damage/DNA Repair; Endocrinology/Hormones; GPCR/G Protein
BTB09089 (GPR65 agonist ) 是一种 T 细胞死亡相关基因 8 (TDAG8/GPR65) 特异性激动剂。BTB09089 诱导TDAG8 的表达,对 T 细胞和巨噬细胞细胞因子的产生进行调节。
T70277 Cynandione A

Others Others
Cynandione A 是从 Cynanchum wilfordii 中提取的苯乙酮,具有抗炎活性,可通过巨噬细胞 α7 nAChR 激活和随后的 IL-10 表达来显着减少促炎细胞因子的过表达。
T16697 Pyronaridine tetraphosphate

Topoisomerase DNA Damage/DNA Repair
Pyronaridine tetraphosphate 是一种具有口服活性的、含甘露醇的DNA 拓扑异构酶 2 的抑制剂和红细胞裂殖杀灭剂,具有抗疟活性和抗肿瘤活性。Pyronaridine tetraphosphate 可治疗 P. falciparum 和 Echinococcus granulosus感染,可减轻埃博拉病毒传播。
T2690 Tranilast

曲尼司特,MK 341,SB 252218

RAAS; Prostaglandin Receptor Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation
Tranilast (SB 252218) 是一种抗过敏药物,可抑制炎症细胞释放脂质介质和细胞因子,抑制前列腺素 D2 (PGD2)产生,IC50为 0.1 mM。它拮抗血管紧张素 II 并抑制其在血管平滑肌细胞中的生物学作用,具有抗炎和免疫调节作用。
T16850 SB-265610

GSK-CXCR2

CXCR Autophagy; GPCR/G Protein; Immunology/Inflammation
SB-265610 (GSK-CXCR2) 是竞争性非肽变构CXCR2选择性拮抗剂,可阻断大鼠 CINC-1 诱导的钙动员和中性粒细胞趋化性,IC50分别为 3.7 和 70 nM。
T4285 Crisaborole

克立硼罗,AN-2728,PF-06930164

PDE Metabolism
Crisaborole (AN-2728) 是一种有效的 PDE4和 cytokine 释放抑制剂,能够抑制 PDE4(IC50=0.49 μM)。
T9853 STING activator Compound 53

STING Immunology/Inflammation
基于 oxindole 核心结构的 STING activator Compound 53 在永生化细胞和原代细胞中表现出强大的 STING(人 EC50 185 nM)的靶向功能激活以及与 STING 激活一致的细胞因子诱导指纹。
T2513 VX-702

p38 MAPK; Autophagy Autophagy; MAPK
VX702 是一种高度特异性的 p38α MAPK 抑制剂,对 p38α 的选择性比 p38β 高 14 倍。它是一种小分子研究口服抗细胞因子疗法,用于治疗炎症性疾病,如类风湿性关节炎。
TP1938L RS09 2TFA (1449566-36-2 free base)

RS09 2TFA 1449566-36-2(free base)

TLR Immunology/Inflammation
RS09 2TFA (1449566-36-2 free base) 是一种 TLR4 激动剂。促进 NF-κB 核转位并在体外诱导 RAW264.7 巨噬细胞分泌炎性细胞因子。它在体内充当佐剂并提高 X-15 特异性抗体血清浓度。
T79365 TIM-3-IN-2

Immunology/Inflammation related Immunology/Inflammation
TIM-3-IN-2 是 Tim3 抑制剂,可以抑制TIM-3与PtdSer、CEACAM1和Gal-9的结合,抑制TIM-3发挥作用。TIM-3-IN-2能够逆转TIM-3介导的促炎细胞因子的作用。
T1127 Beclometasone dipropionate

Beclovent,Beclomethasone dipropionate,二丙酸倍氯米松,丙酸倍氯米松,Beconase,Vancenase

Glucocorticoid Receptor Endocrinology/Hormones
Beclometasone dipropionate (Vancenase) 是具有口服活性的糖皮质激素,具有抗炎和免疫抑制作用。它是Betamethasone 的前体药物,Betamethasone 是 LPS 诱导的炎症及 MMP 释放的抑制剂。
TP1785L Peptide T acetate(106362-32-7 free base)

Others; HIV Protease Microbiology/Virology; Others; Proteases/Proteasome
Peptide T acetate(106362-32-7 free base) 是一种来自 HIV-1 gp120 V2 区域的八肽。它是一种合成八肽,其可能的作用机制是 gp120 对 CD4 受体的竞争性抑制以及与血管肠肽受体的结合和抑制细胞因子作用。
T3520 Setipiprant

KYTH-105,塞替匹仑,ACT-129968

GPR; Prostaglandin Receptor Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation
Setipiprant (ACT-129968) 是一种口服的选择性 CRTH2 拮抗剂,IC50为6.0 nM。
T4403 AX-024 hydrochloride

AX-024 HCl

IL Receptor; TNF; COX; IFNAR; Interleukin Apoptosis; Immunology/Inflammation; Neuroscience
AX-024 hydrochloride (AX-024 HCl) 是一种细胞因子释放抑制剂,可强烈抑制 IL-6、TNFα、IFN-γ、IL-10 和 IL-17A 的产生。它是口服可利用的 TCR-Nck 相互作用抑制剂,可选择性地抑制 TCR 触发的 T 细胞活化。它通过靶向 SH3结构域调节细胞信号传导,具有低毒、高效和高选择性的特点。
T3701 MCC950

CP-456773

NOD Immunology/Inflammation; NF-κB
MCC950 (CP-456773) 是NLRP3的选择性抑制剂,能够作用于BMDMs(IC50:7.5 nM) 和 HMDMs(IC50:8.1 nM)。
T35593 Semapimod tetrahydrochloride

CPSI-2364 tetrahydrochloride

TLR; MAPK Immunology/Inflammation; MAPK
Semapimod tetrahydrochloride (CPSI-2364 tetrahydrochloride) 是一种合成鸟腙丝裂原活化蛋白激酶阻滞剂,也是促炎细胞因子生成抑制剂,干扰巨噬细胞和小胶质细胞功能。Semapimod tetrahydrochloride 可抑制 TLR4 信号传导,抑制 TNF-α、IL-1β 和 IL-6,可用于研究克罗恩病和其他炎症。
T15096 Delgocitinib

JTE-052,迪高替尼,Corectim(Delgocitinib)

Tyrosine Kinases; JAK Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
Delgocitinib(JTE-052)是一种特异性的JAK(Janus激酶)抑制剂,其对JAK1、JAK2、JAK3 和 Tyk2 的 IC50 值分别为 2.8、2.6、13 和 58 nM。Delgocitinib 通过JAK-依赖性细胞因子参与多种炎症和自身免疫性疾病,能有效地遏制多种细胞因子信号传递,同时抑制了因细胞因子而引发的瘙痒。它可广泛用于治疗各种炎症性疾病,包括自身免疫性疾病和超敏反应。
T29021 TT-301

MW 189,MW189,TT301,TT 301,MW 189 ;MW189,MW-189

Others Others
TT-301 is a cytokine inhibitor and glial cell inhibitor.
T70843 Orazipone

Others Others
Orazipone inhibits cytokine production and histamine release; an NSAID.
T69330 CJ-14897

Others Others
CJ-14897 is the (7R,8S)-isomer; a cytokine production inhibitor.
T26687 AV-1101

4OH OPB,4OH-OPB,4OHOPB

Others Others
AV-1101, a cytokine production inhibitor, is used potentially for the treatment of HIV infection.
T33891 PBI-1393

PBI1393,BCH1393,BCH 1393,BCH-1393,PBI 1393

Others Others
PBI-1393 can be used as an enhancer for Th1 type cytokine production and primary T cell activation.
T71264 Tenidap Sodium

Others Others
Tenidap Sodium is a COX/5-LOX inhibitor and cytokine-modulating anti-inflammatory agent.
T6009 TAPI1

TAPI 1,TAPI,TAPI-1

MMP Proteases/Proteasome
TAPI1 (TAPI) 是一种 ADAM17/TACE 抑制剂,可抑制细胞因子受体的脱落。
T69175 Trilobolide

Others Others
Trilobolide is a natural counterpart of thapsigargin and an activator of cytokine secretion.
T28228 Okicenone

Others Others
Okicenone is an antibiotic, interferring with HuR RNA binding, HuR trafficking, T-cell activation and cytokine expression.

化合物

Olprinone
Cat.No: T5033
Synonym: 奥普力农,Loprinone
Target: PDE
SM-324405
Cat.No: T7860
Synonym: SM 324405
Target: TLR
ML604086
Cat.No: T16111
Synonym:
Target: CCR
Aceclofenac
Cat.No: T1421
Synonym: 醋氯芬酸,Preservex,Airtal
Target: COX
LP99
Cat.No: T15784
Synonym:
Target: Epigenetic Reader Domain
Dexamethasone palmitate
Cat.No: T15102
Synonym: 地塞米松棕榈酸酯,DXP
Target: Glucocorticoid Receptor
UCB-9260
Cat.No: T13951
Synonym:
Target: TNF
Salsalate
Cat.No: T0498
Synonym: Disalicylic acid,Salicylsalicylic acid,Sasapyrine,NSC-49171,双水杨酸酯
Target: Reactive Oxygen Species, COX
BAY 11-7082
Cat.No: T1902
Synonym: BAY 11-7821
Target: Apoptosis, Others, IκB/IKK, DUB, Autophagy
JTE-607
Cat.No: T27695
Synonym: JTE-607 dihydrochloride,JTE-607 HCl,甲氧番荔枝碱
Target: Cysteine Protease
6-OAU
Cat.No: T2036
Synonym: GTPL5846
Target: GPR
Hydrocortisone hemisuccinate
Cat.No: T4602
Synonym: Hydrocortisone 21-he,氢化可的松琥珀酸酯,hydrocortisone 21-hemisuccinate*free acid,Hydrocortisone 21-hemisuccinate
Target: Glucocorticoid Receptor, Others, Interleukin
TAPI-1 trifluoroacetate (163847-77-6(free base))
Cat.No: T4122
Synonym:
Target: MMP
G6PDi-1
Cat.No: T8640
Synonym:
Target: Dehydrogenase
SB273005
Cat.No: T6657
Synonym:
Target: Integrin
Atibuclimab
Cat.No: T77484
Synonym:
Target: TNF
TMN355
Cat.No: T13171
Synonym: 2-氯-N-[(9H-芴-9-氨基)羰基]-6-氟苯甲酰胺
Target: Others
(S)-AK-242
Cat.No: T80678
Synonym: (-)-Resatorvid,(S)-Resatorvid,AK-242 (S enantiomer),(-)-AK-242
Target: Others
I942
Cat.No: T24154
Synonym: I 942,I-942
Target: cAMP
IRAK4-IN-7
Cat.No: T5354
Synonym: CA-4948
Target: IRAK
SB 242235
Cat.No: T4078
Synonym: SB-242235,SB242235
Target: p38 MAPK, Autophagy
Peramivir
Cat.No: T21339
Synonym: RWJ270201,BCX 1812,BCX1812,RWJ 270201
Target: Antiviral
M62812
Cat.No: T37292
Synonym:
Target: TLR
GSK2983559 free acid
Cat.No: T11492
Synonym:
Target: Others, RIP kinase
BTB09089
Cat.No: T67892
Synonym: GPR65 agonist (BTB09089)
Target: GPR, DNA
Cynandione A
Cat.No: T70277
Synonym:
Target: Others
Pyronaridine tetraphosphate
Cat.No: T16697
Synonym:
Target: Topoisomerase
Tranilast
Cat.No: T2690
Synonym: 曲尼司特,MK 341,SB 252218
Target: RAAS, Prostaglandin Receptor
SB-265610
Cat.No: T16850
Synonym: GSK-CXCR2
Target: CXCR
Crisaborole
Cat.No: T4285
Synonym: 克立硼罗,AN-2728,PF-06930164
Target: PDE
STING activator Compound 53
Cat.No: T9853
Synonym:
Target: STING
VX-702
Cat.No: T2513
Synonym:
Target: p38 MAPK, Autophagy
RS09 2TFA (1449566-36-2 free base)
Cat.No: TP1938L
Synonym: RS09 2TFA 1449566-36-2(free base)
Target: TLR
TIM-3-IN-2
Cat.No: T79365
Synonym:
Target: Immunology/Inflammation related
Beclometasone dipropionate
Cat.No: T1127
Synonym: Beclovent,Beclomethasone dipropionate,二丙酸倍氯米松,丙酸倍氯米松,Beconase,Vancenase
Target: Glucocorticoid Receptor
Peptide T acetate(106362-32-7 free base)
Cat.No: TP1785L
Synonym:
Target: Others, HIV Protease
Setipiprant
Cat.No: T3520
Synonym: KYTH-105,塞替匹仑,ACT-129968
Target: GPR, Prostaglandin Receptor
AX-024 hydrochloride
Cat.No: T4403
Synonym: AX-024 HCl
Target: IL Receptor, TNF, COX, IFNAR, Interleukin
MCC950
Cat.No: T3701
Synonym: CP-456773
Target: NOD
Semapimod tetrahydrochloride
Cat.No: T35593
Synonym: CPSI-2364 tetrahydrochloride
Target: TLR, MAPK
Delgocitinib
Cat.No: T15096
Synonym: JTE-052,迪高替尼,Corectim(Delgocitinib)
Target: Tyrosine Kinases, JAK
TT-301
Cat.No: T29021
Synonym: MW 189,MW189,TT301,TT 301,MW 189 ;MW189,MW-189
Target: Others
Orazipone
Cat.No: T70843
Synonym:
Target: Others
CJ-14897
Cat.No: T69330
Synonym:
Target: Others
AV-1101
Cat.No: T26687
Synonym: 4OH OPB,4OH-OPB,4OHOPB
Target: Others
PBI-1393
Cat.No: T33891
Synonym: PBI1393,BCH1393,BCH 1393,BCH-1393,PBI 1393
Target: Others
Tenidap Sodium
Cat.No: T71264
Synonym:
Target: Others
TAPI1
Cat.No: T6009
Synonym: TAPI 1,TAPI,TAPI-1
Target: MMP
Trilobolide
Cat.No: T69175
Synonym:
Target: Others
Okicenone
Cat.No: T28228
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T4S0878 Prunetin

樱黄素,Prunusetin

ERK; Dehydrogenase; NF-κB MAPK; Metabolism; NF-κB
Prunetin (Prunusetin) 是一种O-甲基化异黄酮,具有抗炎的作用。它是人醛脱氢酶的有效抑制剂。
T8716 physalin F

酸浆苦味素F,酸浆苦素 F

Apoptosis Apoptosis
Physalin F 是一种分泌型甾体,诱导人外周血单个核细胞凋亡,降低人 T 淋巴细胞 1 型病毒感染后的自发增殖和细胞因子的产生,具有强烈抗炎和免疫调节作用。
T20089 ATP

Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate

Endogenous Metabolite Metabolism
ATP (Adenosine triphosphate) 可为细胞提供能量,参与整体能量平衡,维持细胞内稳态。ATP 可以通过与特异性嘌呤能受体的相互作用充当细胞外信号分子,以介导神经传递、炎症、细胞凋亡和骨重塑等多种过程。
T2812 ATP disodium salt hydrate

ATP disodium,ATP disodium salt,Adenosine disodium triphosphate,三磷酸腺苷二钠盐

Others; Endogenous Metabolite Metabolism; Others
ATP disodium salt hydrate (Adenosine disodium triphosphate) 是体内能量储存和代谢的重要物质,为代谢提供能量,同时在细胞中作为辅酶发挥作用。同时,它是也是免疫和炎症中重要的内源性信号分子。
T1352 ATP disodium salt

Adenosine 5'-triphosphate disodium salt,三磷酸腺苷二钠,ATP,ATP disodium,腺苷-5'-三磷酸二钠盐,Adetide,Adenosine-Triphosphate,Disodium adenosine triphosphate

P2X Receptor; Endogenous Metabolite Membrane transporter/Ion channel; Metabolism; Neuroscience
ATP disodium salt (Adenosine-Triphosphate) 是体内能量储存的重要物质,为代谢提供能量,同时在细胞中作为辅酶发挥作用。Adenosine 5'-triphosphate disodium salt 也是免疫和炎症中重要的内源性信号分子。
TN1818 Kaempferol 3-O-β-D-glucuronide

Kaempferol-3-O-glucuronide,Kaempferol-3-beta-O-glucuronide,山奈酚葡萄糖醛酸苷,Kaempferol-3-glucuronide

IL Receptor Immunology/Inflammation
Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-beta-O-glucuronide) 具有抗氧化活性。 类黄酮葡糖苷酸可以被来自各种人体细胞的微粒体 α2-葡糖苷酸酶解偶联。
TQ0273 Neopterin

D-(+)-Neopterin,2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)pteridin-4(3H)-one,新蝶呤

Endogenous Metabolite Metabolism
Neopterin (D-(+)-Neopterin) 是三磷酸腺苷的一种分解产物,是细胞免疫系统激活的标志物。
TN1131 Handelin

NF-κB; Immunology/Inflammation related Immunology/Inflammation; NF-κB
Handelin 是一种来自 Chrysanthemum boreale 的愈创木酚内酯二聚体,它能够阻碍 NF-κB 活化和促炎细胞因子产生,具有抗炎作用。
T4S1943 Kirenol

奇壬醇,奇任醇,Kirel

Wnt/beta-catenin Cytoskeletal Signaling; Stem Cells
Kirenol (Kirel) 是分离自 Siegesbeckia orientalis 中的,具有抗氧化、抗炎、抗过敏、抗关节炎活性,可用于缓解疼痛的研究。
TN1475 Caulophyllogenin

Segetalic acid

IL Receptor; TNF; PPAR; Immunology/Inflammation related Apoptosis; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism
Caulophyllogenin 是一种部分 PPARγ 激动剂 (EC50 = 12.6 μM),来源于 Kalopanax pictus (五加科) 的茎皮。 Caulophyllogenin 抑制促炎细胞因子分泌,可用于预防和治疗炎症性疾病、2 型糖尿病、肥胖和代谢综合征的研究。
T0632 3,4,5-Trimethoxybenzoic acid

Gallic acid trimethyl ether,Eudesmic acid,3,4,5-三甲氧基苯甲酸,Trimethylgallic Acid,Benzoic acid,Tri-O-methylgallic acid,没食子酸三甲醚

Antioxidant oxidation-reduction
3,4,5-Trimethoxybenzoic acid (Gallic acid trimethyl ether) 是一种苯甲酸衍生物,可用作医药和有机合成中的砌块。
T0131 Cepharanthine

NSC-623442,千金藤碱,千金藤素

Apoptosis; TNF; HIV Protease; Autophagy Apoptosis; Autophagy; Microbiology/Virology; Proteases/Proteasome
Cepharanthine (NSC-623442) 是从Stephania cepharanthaHayata 中提取的一种生物碱,具有抗炎、抗氧化作用。它可抑制肿瘤坏死因子 (TNF)-α 介导的 NFκB 刺激、质膜脂质过氧化和血小板聚集,并抑制细胞因子的产生。
T3S2296 Gardenoside

羟异栀子苷,栀子苷

Others Others
Gardenoside 是一种发现于栀子中的天然化合物,具有保肝作用。它对 FFA 诱导的细胞脂肪变性有抑制作用。它可以调节 P2X3 和 P2X7 受体来抑制慢性缩痛。
T0070 Pentoxifylline

Oxpentifylline,PTX,己酮可可碱,BL-191

HIV Protease; PDE; Adenosine Receptor; Autophagy Autophagy; GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
Pentoxifylline (PTX) 是一种具有口服活性的磷酸二酯酶非选择性抑制剂,具有免疫调节、抗炎、抗纤溶、抗增殖和血液流变学改善作用。它可研究周围血管疾病、脑血管疾病和其他一些涉及局部微循环缺陷的疾病。
TN4234 Hydrangenol

NOS; NF-κB; Nrf2; NO Synthase; Antifection; Autophagy Autophagy; Immunology/Inflammation; Microbiology/Virology; NF-κB
Hydrangenol 是一种天然产物,可从绣球花 (Hydrangea serrata) 的叶中分离。Hydrangenol 是口服有效的抗光老化化合物,可以预防皱纹的形成。Hydrangenol 可以降低 MMP 和炎症细胞因子的表达,增加保湿因子和抗氧化基因的水平。
T5S1981 alpha-Cyperone

(+)-α-Cyperone,α-香附酮,α-Cyperone

Others; Endogenous Metabolite Metabolism; Others
alpha-Cyperone (α-Cyperone) 与 IL-6, Cox-2, Cdc42, Nck-2, Rac1 的表达下调相关,从而能够抑制炎症反应。
T2S2173 (E)-Naringenin chalcone

Isosalipurpol,柚皮苷查尔酮,Chalconaringenin,trans-2'4'6'4-tetrahydroxychalcone,柚皮素查耳酮

Others Others
Naringenin chalcone (Isosalipurpol) 是一种黄酮醇生物合成的中间体,在查耳酮异构酶的作用下,自发代谢成柚皮素。它具有抗炎和抗过敏活性。
T4S0867 Pogostone

DHELWANGIN,广藿香酮

Apoptosis; Antibacterial; Autophagy Apoptosis; Autophagy; Microbiology/Virology
Pogostone (DHELWANGIN) 是从薄荷中分离出,对革兰氏阴性菌、革兰氏阳性菌、大肠埃希菌等具有强效抗菌、抗真菌活性。它诱导细胞凋亡和自噬。
T3795 Corilagin

Apoptosis; TLR; Reverse Transcriptase; Antibacterial; Autophagy Apoptosis; Autophagy; Immunology/Inflammation; Microbiology/Virology
Corilagin 是一种鞣酸,有抑制 RNA 肿瘤病毒逆转录酶的活性。它抑制金黄色葡萄球菌的生长,MIC 为 25 μg/mL。它有抗肿瘤活性,可用于肝癌和卵巢癌。
T3753 Sinapinic Acid

Sinapic acid,芥子酸,Synapoic acid

Apoptosis; RAAS; Reactive Oxygen Species; HDAC Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Endocrinology/Hormones; Immunology/Inflammation; Metabolism; NF-κB
Sinapinic Acid (Synapoic acid) 是从 Hydnophytum formicarumJack. 根中分离到的酚类,是HDAC 抑制剂,对ACE-I 的活性也有抑制作用。它有抗肿瘤活性,诱导肿瘤细胞凋亡,具有抗氧化、抗糖尿病的作用。
T3929 Kaurenoic acid

Kauren-19-Oic Acid,异贝壳杉烯酸,kaurenoate,kaur-16-en-18-oic acid

Others Others
Kaurenoic acid (kaurenoate) 是一种二萜,来源于 Sphagneticola trilobata 中,可以抑制细胞因子的产生和激活 NO–cyclic GMP–PKG–ATP- 敏感型钾通道信号通路,并抑制炎症疼痛。
T0798 Triamcinolone

Fluoxyprednisolone,曲安西龙,Aristocort,Rodinolone

Glucocorticoid Receptor; COX Endocrinology/Hormones; Immunology/Inflammation; Neuroscience
Triamcinolone (Aristocort) 是一种皮质类固醇激素受体激动剂,也是一种合成的长效糖皮质激素,具有抗炎活性。
T4S2326 Cornuside

7-Galloylsecologanol,7-O-Galloylsecologanol,山茱萸新苷,Comuside

ERK; p38 MAPK; NF-κB; JNK MAPK; NF-κB
Cornuside (Comuside) 是从山茱萸的果实中分离出的环烯醚萜苷,可用于炎症疾病的研究和促进血液循环。 它通过下调 MAPK 和 NF-κB 信号通路抑制肥大细胞介导的过敏反应,用于炎性过敏性疾病中的潜能。
T4S2063 Tetrahydrocoptisine

人血草碱,STYLOPINE

ERK; p38 MAPK; NF-κB MAPK; NF-κB
Tetrahydrocoptisine (STYLOPINE) 具有抑制炎症的有效作用。它通过抑制 NF-κB 信号通路对 LPS 诱导的 ALI 具有保护作用,这可能涉及抑制肺部炎症过程。它具有胃保护活性,归因于减少 NO 产生和调节促炎细胞因子,抑制中性粒细胞积累和 NF-κB 表达。它是一种活性抗炎成分,通过下调 NF-κB 活化、磷酸化 ERK1/2 和磷酸化-p38MAPK 信号通路抑制 TNF-α、IL-6 和 NO 的产生。
TN3901 Dulcioic acid

Others Others
Dulcioic acid shows a significant inhibitory effect on cytokine production.
TN4093 Galeopsin

TNF Apoptosis
Galeopsin shows potential anti-inflammatory activity by inhibiting proinflammatory cytokine TNF-α, it has anti-proliferative effect on several cancer cell lines.
T13628 Curvularin

(S)-Curvularin

NOS Immunology/Inflammation
Curvulin, naturally isolated from Campylobacter curvulans, is a fungal metabolite and a potent mycotoxin that inhibits cytokine-induced nitric oxide synthase (iNOS) with IC50 of 9.5 µM.
TN2327 Zedoarondiol

蓬莪二醇

NOS; NF-κB; COX Immunology/Inflammation; Neuroscience; NF-κB
Zedoarondiol has anti-inflammatory activity, inhibits iNOS, COX-2, and pro-inflammatory cytokine expressions by suppressing the phosphorylations of IKK and MAPKs, and by subsequently inactivating the NF-kappaB pathway.
T16332 NKH477

Colforsin dapropate hydrochloride

NMDAR Neuroscience
NKH477 is a novel water-soluble forskolin derivative that improves cardiac failure mainly through its beneficial effects on diastolic cardiac function. NKH477 shows an antiproliferative effect in vivo with an altered cytokine profile to inhibit the acute
T27282 Erucin

AR 1G3839,AR-1G3839,CCRIS-9056,CCRIS9056,AR1G3839,CCRIS 9056

Erucin is a sulforaphane analog found in cruciferous vegtables. Erucin is a telomerase inhibitor. It induces phase II enzyme activity, suppresses cellular proliferation in hepatocellular carcinoma cells, prevents 6-OHDA-induced neurodegenration, and inhib
TN4437 Licorisoflavan A

MMP; IL Receptor; NF-κB; DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; NF-κB; Proteases/Proteasome
Licorisoflavan A shows weak scavenging activity against superoxide anion radical, it and licoricidin have potential for the development of novel host-modulating strategies for the treatment of cytokine and/or MMP-mediated disorders such as periodontitis.L
TN5593 Euphohelioscopin A

Euphohelioscopin A, an activator of protein kinase C (PKC), it inhibits proliferation and induces differentiation of the myeloid leukemia cell lines THP-1 and HL-60. Euphohelioscopin A has anti-inflammary activity, it exhibits moderate inhibitory activity
T36417 Nargenicin

Antibiotic 47444

Others Others
Nargenicin is a macrolide antibiotic that selectively inhibits the growth of S. aureus, methicilin resistant S. aureus (MRSA), and M. luteus (MICs = 0.6, 0.3, and 2.5 μg/ml, respectively) over a panel of 11 Gram-positive and Gram-negative bacteria (MICs = >80 μg/ml). [1] It dose-dependently inhibits S. aureus DnaE in the presence of DNase I-activated DNA and E. coli DnaE when used at concentrations of 0.00001-0.1 and 0.01-100 μg/mL, respectively. [2] In murine BV-2 microglial cells, nargenicin (...
TN4778 Physalin H

gp120/CD4; Antifection; Autophagy Autophagy; Immunology/Inflammation; Microbiology/Virology
Physalin H is an Hh signaling inhibitor blocks GLI1-DNA-complex formation, it also strong quinone reductase induction activity with IR (Induction ratio, QR induction activity) value of 3.74±0.02. Physalin H shows immunosuppressive effects on T cells both
TN5153 Torilin

MMP; ERK; IκB/IKK; p38 MAPK; NF-κB; Tyrosinase; Reductase; DNA/RNA Synthesis; JNK Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Endocrinology/Hormones; MAPK; Metabolism; NF-κB; Proteases/Proteasome
Torilin 是一种睾酮5α还原酶抑制剂,它(IC50=31.7+/-4.23μM)对5α还原酶的抑制作用强于α-亚麻酸(IC50=160.3+/-24.62μM),但弱于非那雄胺(IC50=0.38+/-0.06μM)。Torilin 具有免疫调节、肝脏保护和抗炎特性,它通过限制 TAK1介导的 MAP 激酶和 NF-βB 活化来抑制炎症,它可以减轻关节炎的严重程度,改变 dLN 或关节中的白细胞活化,并恢复血清和脾细胞细胞因子失衡。托利林抑制α-黑素细胞刺激激素激活的 B16黑色素瘤细胞中的黑色素生成,IC(50)值为25μM。Torilin 对枯草芽孢杆菌 ATCC 6633孢子和营养细胞表现出优异的抗菌活性。Torilin 在体内和体外都具有强大的抗血管生成活性,它可能通过抑制肿瘤侵袭来抑制肿瘤发生,逆转癌细胞的多药耐药性,它可以增强阿霉素、长春碱、紫杉醇和秋水仙碱对多药耐药 KB-V1和 MCF7/ADR 细胞的细胞毒性。

天然产物

Prunetin
Cat.No: T4S0878
Synonym: 樱黄素,Prunusetin
Target: ERK, Dehydrogenase, NF-κB
physalin F
Cat.No: T8716
Synonym: 酸浆苦味素F,酸浆苦素 F
Target: Apoptosis
ATP
Cat.No: T20089
Synonym: Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate
Target: Endogenous Metabolite
ATP disodium salt hydrate
Cat.No: T2812
Synonym: ATP disodium,ATP disodium salt,Adenosine disodium triphosphate,三磷酸腺苷二钠盐
Target: Others, Endogenous Metabolite
ATP disodium salt
Cat.No: T1352
Synonym: Adenosine 5'-triphosphate disodium salt,三磷酸腺苷二钠,ATP,ATP disodium,腺苷-5'-三磷酸二钠盐,Adetide,Adenosine-Triphosphate,Disodium adenosine triphosphate
Target: P2X Receptor, Endogenous Metabolite
Kaempferol 3-O-β-D-glucuronide
Cat.No: TN1818
Synonym: Kaempferol-3-O-glucuronide,Kaempferol-3-beta-O-glucuronide,山奈酚葡萄糖醛酸苷,Kaempferol-3-glucuronide
Target: IL Receptor
Neopterin
Cat.No: TQ0273
Synonym: D-(+)-Neopterin,2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)pteridin-4(3H)-one,新蝶呤
Target: Endogenous Metabolite
Handelin
Cat.No: TN1131
Synonym:
Target: NF-κB, Immunology/Inflammation related
Kirenol
Cat.No: T4S1943
Synonym: 奇壬醇,奇任醇,Kirel
Target: Wnt/beta-catenin
Caulophyllogenin
Cat.No: TN1475
Synonym: Segetalic acid
Target: IL Receptor, TNF, PPAR, Immunology/Inflammation related
3,4,5-Trimethoxybenzoic acid
Cat.No: T0632
Synonym: Gallic acid trimethyl ether,Eudesmic acid,3,4,5-三甲氧基苯甲酸,Trimethylgallic Acid,Benzoic acid,Tri-O-methylgallic acid,没食子酸三甲醚
Target: Antioxidant
Cepharanthine
Cat.No: T0131
Synonym: NSC-623442,千金藤碱,千金藤素
Target: Apoptosis, TNF, HIV Protease, Autophagy
Gardenoside
Cat.No: T3S2296
Synonym: 羟异栀子苷,栀子苷
Target: Others
Pentoxifylline
Cat.No: T0070
Synonym: Oxpentifylline,PTX,己酮可可碱,BL-191
Target: HIV Protease, PDE, Adenosine Receptor, Autophagy
Hydrangenol
Cat.No: TN4234
Synonym:
Target: NOS, NF-κB, Nrf2, NO Synthase, Antifection, Autophagy
alpha-Cyperone
Cat.No: T5S1981
Synonym: (+)-α-Cyperone,α-香附酮,α-Cyperone
Target: Others, Endogenous Metabolite
(E)-Naringenin chalcone
Cat.No: T2S2173
Synonym: Isosalipurpol,柚皮苷查尔酮,Chalconaringenin,trans-2'4'6'4-tetrahydroxychalcone,柚皮素查耳酮
Target: Others
Pogostone
Cat.No: T4S0867
Synonym: DHELWANGIN,广藿香酮
Target: Apoptosis, Antibacterial, Autophagy
Corilagin
Cat.No: T3795
Synonym:
Target: Apoptosis, TLR, Reverse Transcriptase, Antibacterial, Autophagy
Sinapinic Acid
Cat.No: T3753
Synonym: Sinapic acid,芥子酸,Synapoic acid
Target: Apoptosis, RAAS, Reactive Oxygen Species, HDAC
Kaurenoic acid
Cat.No: T3929
Synonym: Kauren-19-Oic Acid,异贝壳杉烯酸,kaurenoate,kaur-16-en-18-oic acid
Target: Others
Triamcinolone
Cat.No: T0798
Synonym: Fluoxyprednisolone,曲安西龙,Aristocort,Rodinolone
Target: Glucocorticoid Receptor, COX
Cornuside
Cat.No: T4S2326
Synonym: 7-Galloylsecologanol,7-O-Galloylsecologanol,山茱萸新苷,Comuside
Target: ERK, p38 MAPK, NF-κB, JNK
Tetrahydrocoptisine
Cat.No: T4S2063
Synonym: 人血草碱,STYLOPINE
Target: ERK, p38 MAPK, NF-κB
Dulcioic acid
Cat.No: TN3901
Synonym:
Target: Others
Galeopsin
Cat.No: TN4093
Synonym:
Target: TNF
Curvularin
Cat.No: T13628
Synonym: (S)-Curvularin
Target: NOS
Zedoarondiol
Cat.No: TN2327
Synonym: 蓬莪二醇
Target: NOS, NF-κB, COX
NKH477
Cat.No: T16332
Synonym: Colforsin dapropate hydrochloride
Target: NMDAR
Erucin
Cat.No: T27282
Synonym: AR 1G3839,AR-1G3839,CCRIS-9056,CCRIS9056,AR1G3839,CCRIS 9056
Target:
Licorisoflavan A
Cat.No: TN4437
Synonym:
Target: MMP, IL Receptor, NF-κB, DNA/RNA Synthesis
Euphohelioscopin A
Cat.No: TN5593
Synonym:
Target:
Nargenicin
Cat.No: T36417
Synonym: Antibiotic 47444
Target: Others
Physalin H
Cat.No: TN4778
Synonym:
Target: gp120/CD4, Antifection, Autophagy
Torilin
Cat.No: TN5153
Synonym:
Target: MMP, ERK, IκB/IKK, p38 MAPK, NF-κB, Tyrosinase, Reductase, DNA/RNA Synthesis, JNK
Cat. No. Product Name Species Expression System
TMPY-05242 CRLF2/TSLPR Protein, Human, Recombinant (His)

CRL2,CRLF2Y,TSLPR,cytokine receptor-like factor 2

Human HEK293 Cells
CRLF2/TSLPR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is D0E2W4.
TMPY-00044 CYTL1 Protein, Human, Recombinant (mFc)

C4orf4,C17,cytokine-like 1

Human HEK293 Cells
Cytokine-like protein 1 (CYTL1) is a small widely expressed secreted protein lacking significant primary sequence homology to any other known protein. Cytokine-like 1 (CYTL1) is a novel potential cytokine that was first identified in CD34(+) cells derived from bone marrow and cord blood, and it was also found using our immunogenomics strategy. CYTL1 expression appears to be highest in the hematopoietic system and in chondrocytes; however, maintenance of cartilage in mouse models of arthritis is ...
TMPH-01187 CRLF1 Protein, Human, Recombinant (E. coli, His & Myc)

Cytokine-like factor 1,Cytokine receptor-l...

Human E. coli
CRLF1 Protein, Human, Recombinant (E. coli, His & Myc) is expressed in E. coli.
TMPH-01188 CRLF1 Protein, Human, Recombinant (His & Myc)

CRLF1,Cytokine receptor-like factor 1,ZcytoR5,CLF-1...

Human Baculovirus Insect Cells
CRLF1 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.
TMPH-01189 CISH Protein, Human, Recombinant (GST)

Suppressor of cytokine signaling,Cytokine-...

Human E. coli
CISH Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 55.7 kDa and the accession number is Q9NSE2.
TMPK-00929 FLT3 Protein, Mouse, Recombinant (hFc)

FL,FLT3LG,Flt3L,SL cytokine,Flt3 ligand

Mouse HEK293 Cells
Flt‑3 Ligand, also known as FL, is an alpha -helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages.Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. FLT3 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 84.78 kDa and the accession number is Q00342.
TMPH-03076 Astakine Protein, Pacifastacus leniusculus, Recombinant (His & Myc)

Prokineticin-like cytokine,Astakine

Pacifastacus leniusculus E. coli
Cytokine directly involved in hematopoiesis. Astakine Protein, Pacifastacus leniusculus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 16.2 kDa and the accession number is Q56R11.
TMPJ-00633 IL-17F Protein, Cynomolgus, Recombinant (His)

IL17F,Cytokine ML-1,IL-17F,Interleukin-17F

Cynomolgus HEK293 Cells
IL-17F Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 19-22 KDa and the accession number is G7P4V0.
TMPK-00125 FLT3 Ligand Protein, Human, Recombinant (hFc)

FLT3LG,FL,Flt3 ligand,SL cytokine,Flt3L

Human HEK293 Cells
Flt‑3 Ligand, also known as FL, is an alpha -helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages.Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. FLT3 Ligand Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 44.8 kDa and the accession number is P49771-1.
TMPH-01551 IFNLR1 Protein, Human, Recombinant (His & SUMO)

Cytokine receptor class-II member 12,Likely interle...

Human E. coli
The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primar...
TMPK-00084 IL-17C Protein, Human, Recombinant (His & Avi)

IL-17C,Cytokine CX2,IL17C,CX2,IL-17CMGC126884

Human HEK293 Cells
Interleukin‑17C (IL‑17C) is a 15‑20 kDa glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold. IL‑17C is Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by sig...
TMPJ-00531 TSLPR Protein, Mouse, Recombinant (His)

Cytokine receptor-like 2,Thymic stromal-derived lym...

Mouse HEK293 Cells
TSLPR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 35-40 KDa and the accession number is AAH23788.1.
TMPJ-00573 IL-17F Protein, Human, Recombinant (His)

IL17F,IL-17F,Cytokine ML-1,Interleukin-17F

Human HEK293 Cells
IL-17F Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 19 KDa and the accession number is AAH70124.1.
TMPJ-00607 RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)

Receptor activator of nuclear factor κ-B ligand,Osteoprotege...

Mouse HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 30-35 KDa and the accession number is BAA97257.1.
TMPY-05769 CRLF2/TSLPR Protein, Human, Recombinant (hFc)

CRLF2Y,cytokine receptor-like factor 2,CRL2,TSLPR

Human HEK293 Cells
CRLF2/TSLPR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.91 kDa and the accession number is D0E2W4.
TMPH-02852 FAM3B Protein, Mouse, Recombinant (His & Myc)

Fam3b,Cytokine-like protein 2-21,Protein FAM3B,Panc...

Mouse Baculovirus Insect Cells
Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner.
TMPK-00051 IL-20 Protein, Human, Recombinant (hFc)

白细胞介素,MGC96907,白介素,IL10D,Cytokine Zcyto10,IL-20,Zcy...

Human HEK293 Cells
Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progression has not yet been investigated. In addition, IL-20 expression was significantly associated with tumor size, metastasis, TNM stage and poor prognosis in patients with HCC. IL-20 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predic...
TMPK-01198 IL-20 Protein, Mouse, Recombinant (His)

Cytokine Zcyto10,IL-20,白细胞介素,IL10D,白介素,Zcyto10,MGC9...

Mouse HEK293 Cells
Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progression has not yet been investigated. In addition, IL-20 expression was significantly associated with tumor size, metastasis, TNM stage and poor prognosis in patients with HCC. IL-20 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predic...
TMPJ-00974 XCL1 Protein, Human, Recombinant (hFc & His)

Cytokine SCM-1,Lymphotaxin,LTN,XC chemokine ligand ...

Human HEK293 Cells
Lymphotactin is a secreted protein which belongs to the intercrine gamma family. It is also a member of the XC chemokine family. XCL1 is found in spleen with highest level, lower in peripheral leukocytes and very low levels in lung, colon and small intestine. XCL1 plays a role in inflammatory and immunological responses, inducing leukocyte migration and activation. XCL1 induces chemotactic function by binding to a chemokine receptor called XCR1. XCL1 is closely related to another chemokine calle...
TMPJ-00123 FLT3LG Protein, Mouse, Recombinant (His)

Fms-related tyrosine kinase 3 ligand (Flt3L),Flt3 ligand,SL ...

Mouse HEK293 Cells
Fms-related tyrosine kinase 3 ligand(Flt3L) is a single-pass type I membrane protein and consists of 232 amino acids. Flt3L is a hematopoietic four helical bundle cytokine, structurally homologous to stem cell factor and colony stimulating factor. Flt3L synergizes well with a number of other colony stimulating factors and interleukins. Flt3L stimulates the proliferation and differentiation of various blood cell progentiors by activating FLT3.
TMPJ-00046 IL-17F Protein, Human, Recombinant

IL17F,白介素,IL-17F,Interleukin-17F,白细胞介素,Cytokine ML-...

Human E. coli
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today, IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F also regulates cartilage mat...
TMPJ-00530 TSLPR Protein, Mouse, Recombinant (hFc)

CRLF2,CRL2 cytokine receptor,TSLPR,CRL2,P2RY8/CRLF2...

Mouse HEK293 Cells
TSLPR Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 62-88 KDa and the accession number is AAH23788.1.
TMPJ-01394 CXCL15 Protein, Mouse, Recombinant (His)

Lungkine,C-X-C motif chemokine 15,Small-inducible cytoki...

Mouse HEK293 Cells
Mouse C-X-C motif chemokine 15, also known as Cxcl15, is a secreted protein which is member of the ELR motif-containing CXC chemokines. It expressed at low levels in fetal lung, the expression restricted to the lung, produced by bronchoepithelial cells and is released into the airways. It plays an important role in lung-specific neutrophil trafficking during normal and inflammatory conditions. It also appears chemotactic for neutrophils.
TMPK-00046 IL-17F Protein, Human, Recombinant (His & Avi), Biotinylated

CANDF6,IL-24,IL24,IL17F,Cytokine ML-1,IL-17F,ML1

Human HEK293 Cells
IL-17F Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.5 /14.9 kDa and the accession number is Q96PD4.
TMPK-00041 IL-17F Protein, Mouse, Recombinant (His & Avi)

IL-24,IL17F,ML1,IL-17F,Cytokine ML-1,CANDF6,IL24

Mouse HEK293 Cells
IL-17F Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.8 kDa and the accession number is Q7TNI7-1.
TMPJ-00078 IL-17C Protein, Human, Recombinant (His)

CX2,IL-17C,interleukin-17C,IL17C,IL-17CMGC126884,Cytokin...

Human HEK293 Cells
IL-17C Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 19 KDa and the accession number is Q9P0M4.
TMPJ-00213 IL-10R beta/IL-10RB Protein, Human, Recombinant (hFc)

Cytokine receptor family 2 member 4,Interleukin-10 ...

Human HEK293 Cells
Interleukin-10 receptor subunit beta(IL10RB), also known as Cytokine receptor class-II member 4,Cytokine receptor family 2 member 4,Interleukin-10 receptor subunit 2, belongs to the type II cytokine receptor family. IL10RB is a single- pass type I membrane protein and contains two fibronectin type-III domains. It is an accessory chain which is essential for the active interleukin 10 receptor complex. Coexpression of IL10RB and IL10RA proteins has been shown to be required for IL10-induced signal...
TMPK-01197 IL-20 Protein, Mouse, Recombinant (hFc)

白细胞介素,IL-20,IL10D,Zcyto10,Cytokine Zcyto10,白介素,MGC9...

Mouse HEK293 Cells
Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progression has not yet been investigated. In addition, IL-20 expression was significantly associated with tumor size, metastasis, TNM stage and poor prognosis in patients with HCC. IL-20 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predic...
TMPK-00060 IL-17B Protein, Mouse, Recombinant (His)

IL20,interleukin 17B,interleukin 20,IL-17B,MGC138901,ZCYTO7,...

Mouse E. coli
IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tumorigenesis and resistance to anticancer therapies. IL-17B/IL-17RB expression patterns and biological activities in cancer and highlight issues that remain to be addressed to better characterize IL-17B and its receptor as potential targets for enhancing the effectiveness of the existing cancer therapies.
TMPJ-00077 IL -17C Protein, Human, Recombinant (His & Avi), Biotinylated

Cytokine CX2,CX2,IL17C,interleukin 17C,IL-17C,inter...

Human HEK293 Cells
IL -17C Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 24-26 KDa and the accession number is Q9P0M4.
TMPK-00042 IL-17F Protein, Mouse, Recombinant (His & Avi), Biotinylated

CANDF6,ML1,Cytokine ML-1,IL17F,IL-24,IL24,IL-17F

Mouse HEK293 Cells
IL-17F Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.8 kDa and the accession number is Q7TNI7-1.
TMPH-00930 Anamorsin Protein, Human, Recombinant (His & SUMO)

CIAPIN1,Fe-S cluster assembly protein DRE2 homolog,Cytok...

Human E. coli
Anamorsin Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.6 kDa and the accession number is Q6FI81.
TMPH-02853 FAM3B Protein, Mouse, Recombinant (hFc)

Fam3b,Cytokine-like protein 2-21,Protein FAM3B,Panc...

Mouse HEK293 Cells
Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner.
TMPK-00052 IL-20 Protein, Human, Recombinant (His)

白细胞介素,MGC96907,Zcyto10,IL-20,白介素,IL10D,Cytokine Zcy...

Human HEK293 Cells
Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progression has not yet been investigated. In addition, IL-20 expression was significantly associated with tumor size, metastasis, TNM stage and poor prognosis in patients with HCC. IL-20 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predic...
TMPY-02194 SOCS3 Protein, Human, Recombinant (His & Trx)

SOCS-3,SSI-3,ATOD4,Cish3,SSI3,suppressor of cytokine

Human E. coli
Suppressor of cytokine signaling 3, also known as SOCS-3, Cytokine-inducible SH2 protein 3, CIS-3, STAT-induced STAT inhibitor 3, SOCS3 and CIS3, is a protein which is widely expressed with high expression in heart, placenta, skeletal muscle, peripheral blood leukocytes, fetal and adult lung, and fetal liver and kidney. SOCS3 / CIS3 contains one SH2 domain and one SOCS box domain. SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. ...
TMPJ-00991 S100A8 Protein, Rat, Recombinant (His)

Leukocyte L1 complex light chain,Migration inhibitory factor...

Rat E. coli
Protein S100-A8(Mrp8) contains 2 EF-hand domains and belongs to the S-100 family. Mrp8 binds two calcium ions per molecule with an affinity similar to that of the S-100 proteins. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. It may function in the inhi...
TMPY-00550 NNT1/CLCF1 Protein, Human, Recombinant (hFc)

NNT-1,CLC,NNT1,NR6,BSF3,cardiotrophin-like cytokine...

Human HEK293 Cells
NNT1/CLCF1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.7 kDa and the accession number is Q9UBD9-1.
TMPH-02919 SOCS1 Protein, Mouse, Recombinant (His & Myc)

STAT-induced STAT inhibitor 1,Suppressor of cytokine

Mouse E. coli
SOCS1 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.7 kDa and the accession number is O35716.
TMPJ-01001 CCL11 Protein, Human, Recombinant

SCYA11,C-C Motif Chemokine 11,Eosinophil Chemotactic Protein...

Human E. coli
C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 selectively recruits eosinophils, a prominent feature of allergic inflammatory reactions. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for CCL11 include CCR2, CCR3 and CCR5. However, it has been found that CCL11 has high degree selectivity for its recept...
TMPK-00661 IL-22 Protein, Cynomolgus, Recombinant (His)

TIFIL-23,IL-22,IL-D110,IL-TIF,TIFa,Interleukin-22,Cytoki...

Cynomolgus HEK293 Cells
The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeability, production of mucus and antimicrobial proteins (AMPs), and complement production. IL-22 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 17.69 kDa and the accession number is G7PHZ7.
TMPJ-01414 GDF-15 Protein, Mouse, Recombinant (His & Flag)

Growth Differentiation Factor 15, Macrophage inhibitory ...

Mouse HEK293 Cells
Growth Differentiation Factor 15 (GDF-15), also called Macrophage Inhibitory Cytokine 1 (MIC-1), is a divergent member of the TGF-beta superfamily. GDF15 can be secreted by a wide variety of cell types in response to a broad range of stressors. GDF-15 expression is dramatically upregulated during acute brain injury, cancer, cardiovascular disease, and inflammation, suggesting its potential value as a disease biomarker. GDF15 was shown to inhibit proliferation of primitive hematopoietic progenito...
TMPK-00568 IL-9 Protein, Cynomolgus, Recombinant (His)

P40,HP40,IL-9,T-cell growth factor P40,Interleukin-9,Cyt...

Cynomolgus HEK293 Cells
IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as cancer, autoimmunity and other pathogen-mediated immune-regulated diseases. In this review, we focus on the role of Th9 and IL-9-producing cells in allergic asthma. IL-9 Protein, Cynomolgu...
TMPJ-01341 CCL24 Protein, Mouse, Recombinant

Scya24,Eosinophil chemotactic protein 2,Small-inducible ...

Mouse E. coli
Mouse CCL24 is a secreted protein, which is a member of the CC chemokine subfamily. Mouse Ccl24 cDNA encodes a 119 amino acid residue precursor protein, shares approximately 58% amino acid sequence identity with human Ccl24. It is predominantly expressed in the jejunum and spleen and also be induced in the lung by allergen challengeand IL4. Mouse ccl24 has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Ccl24 is chemotactic for resting T-lymphocytes, ...
TMPH-02740 IL-31R alpha Protein, Mouse, Recombinant (His)

ZcytoR17,Interleukin-31 receptor subunit alpha,Novel cyt...

Mouse E. coli
Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro. IL-31R alpha Protein, Mouse, Recombinant (His) is expressed in E. coli expression...
TMPK-00026 IL-9 Protein, Mouse, Recombinant (hFc)

P40,IL-9,Interleukin-9,Cytokine P40,T-cell growth f...

Mouse HEK293 Cells
IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as cancer, autoimmunity and other pathogen-mediated immune-regulated diseases. In this review, we focus on the role of Th9 and IL-9-producing cells in allergic asthma. IL-9 Protein, Mouse, Re...
TMPH-02155 SOCS1 Protein, Human, Recombinant (E. coli, His)

Tec-interacting protein 3,JAK-binding protein,Suppressor of ...

Human E. coli
SOCS1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 27.6 kDa and the accession number is O15524.
TMPJ-00852 CCL2 Protein, Rat, Recombinant (His)

C-C motif chemokine 2,Small-inducible cytokine A2,M...

Rat HEK293 Cells
Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, is a member of the beta (C-C) subfamily of chemokines that is a chemoattractant for monocytes and basophils but not eosinophils or neutrophils. CCL2 binds the cognate receptor CCR2, and together this signaling pair has been shown to have multiple pro-tumorigenic roles, from mediating tumor growth and angiogenesis to recruiting and usurping host stromal cells to support tumor progression. CCL2 is found in the circulation, where it has ...
TMPJ-00119 IL-22RA2 Protein, Human, Recombinant (hFc)

Cytokine Receptor Family 2 Member 10,CRF2-10,IL-22R...

Human HEK293 Cells
Interleukin-22 Receptor Subunit α-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. IL22RA2 functions as an IL22 antagonist and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
TMPH-02156 SOCS1 Protein, Human, Recombinant (His)

SOCS1,STAT-induced STAT inhibitor 1,JAK-binding protein,Tec-...

Human P. pastoris (Yeast)
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS1 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway. Through binding to JAKs and IFNGR1, inhibits their kinase activity. In vitro, also suppresses Tec protein-tyrosine activity. Appears to be a major regulator of signaling by interleukin 6 (IL6) and leukemia inhibitory factor (LIF). Regulates interferon-gamma mediated sensory neuron surviv...
TMPK-00025 IL-9 Protein, Human, Recombinant (hFc)

HP40,Cytokine P40,白细胞介素,Interleukin-9,白介素,P40,T-cel...

Human HEK293 Cells
IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as cancer, autoimmunity and other pathogen-mediated immune-regulated diseases. In this review, we focus on the role of Th9 and IL-9-producing cells in allergic asthma. IL-9 Protein, Human, Re...
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重组蛋白

CRLF2/TSLPR Protein, Human, Recombinant (His)
Cat.No: TMPY-05242
Species: Human
Expression System: HEK293 Cells
CYTL1 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-00044
Species: Human
Expression System: HEK293 Cells
CRLF1 Protein, Human, Recombinant (E. coli, His & Myc)
Cat.No: TMPH-01187
Species: Human
Expression System: E. coli
CRLF1 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01188
Species: Human
Expression System: Baculovirus Insect Cells
CISH Protein, Human, Recombinant (GST)
Cat.No: TMPH-01189
Species: Human
Expression System: E. coli
FLT3 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-00929
Species: Mouse
Expression System: HEK293 Cells
Astakine Protein, Pacifastacus leniusculus, Recombinant (His & Myc)
Cat.No: TMPH-03076
Species: Pacifastacus leniusculus
Expression System: E. coli
IL-17F Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-00633
Species: Cynomolgus
Expression System: HEK293 Cells
FLT3 Ligand Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00125
Species: Human
Expression System: HEK293 Cells
IFNLR1 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01551
Species: Human
Expression System: E. coli
IL-17C Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00084
Species: Human
Expression System: HEK293 Cells
TSLPR Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00531
Species: Mouse
Expression System: HEK293 Cells
IL-17F Protein, Human, Recombinant (His)
Cat.No: TMPJ-00573
Species: Human
Expression System: HEK293 Cells
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00607
Species: Mouse
Expression System: HEK293 Cells
CRLF2/TSLPR Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05769
Species: Human
Expression System: HEK293 Cells
FAM3B Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02852
Species: Mouse
Expression System: Baculovirus Insect Cells
IL-20 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00051
Species: Human
Expression System: HEK293 Cells
IL-20 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01198
Species: Mouse
Expression System: HEK293 Cells
XCL1 Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-00974
Species: Human
Expression System: HEK293 Cells
FLT3LG Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00123
Species: Mouse
Expression System: HEK293 Cells
IL-17F Protein, Human, Recombinant
Cat.No: TMPJ-00046
Species: Human
Expression System: E. coli
TSLPR Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00530
Species: Mouse
Expression System: HEK293 Cells
CXCL15 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01394
Species: Mouse
Expression System: HEK293 Cells
IL-17F Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00046
Species: Human
Expression System: HEK293 Cells
IL-17F Protein, Mouse, Recombinant (His & Avi)
Cat.No: TMPK-00041
Species: Mouse
Expression System: HEK293 Cells
IL-17C Protein, Human, Recombinant (His)
Cat.No: TMPJ-00078
Species: Human
Expression System: HEK293 Cells
IL-10R beta/IL-10RB Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00213
Species: Human
Expression System: HEK293 Cells
IL-20 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-01197
Species: Mouse
Expression System: HEK293 Cells
IL-17B Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00060
Species: Mouse
Expression System: E. coli
IL -17C Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00077
Species: Human
Expression System: HEK293 Cells
IL-17F Protein, Mouse, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00042
Species: Mouse
Expression System: HEK293 Cells
Anamorsin Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-00930
Species: Human
Expression System: E. coli
FAM3B Protein, Mouse, Recombinant (hFc)
Cat.No: TMPH-02853
Species: Mouse
Expression System: HEK293 Cells
IL-20 Protein, Human, Recombinant (His)
Cat.No: TMPK-00052
Species: Human
Expression System: HEK293 Cells
SOCS3 Protein, Human, Recombinant (His & Trx)
Cat.No: TMPY-02194
Species: Human
Expression System: E. coli
S100A8 Protein, Rat, Recombinant (His)
Cat.No: TMPJ-00991
Species: Rat
Expression System: E. coli
NNT1/CLCF1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00550
Species: Human
Expression System: HEK293 Cells
SOCS1 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02919
Species: Mouse
Expression System: E. coli
CCL11 Protein, Human, Recombinant
Cat.No: TMPJ-01001
Species: Human
Expression System: E. coli
IL-22 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00661
Species: Cynomolgus
Expression System: HEK293 Cells
GDF-15 Protein, Mouse, Recombinant (His & Flag)
Cat.No: TMPJ-01414
Species: Mouse
Expression System: HEK293 Cells
IL-9 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00568
Species: Cynomolgus
Expression System: HEK293 Cells
CCL24 Protein, Mouse, Recombinant
Cat.No: TMPJ-01341
Species: Mouse
Expression System: E. coli
IL-31R alpha Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02740
Species: Mouse
Expression System: E. coli
IL-9 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-00026
Species: Mouse
Expression System: HEK293 Cells
SOCS1 Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-02155
Species: Human
Expression System: E. coli
CCL2 Protein, Rat, Recombinant (His)
Cat.No: TMPJ-00852
Species: Rat
Expression System: HEK293 Cells
IL-22RA2 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00119
Species: Human
Expression System: HEK293 Cells
SOCS1 Protein, Human, Recombinant (His)
Cat.No: TMPH-02156
Species: Human
Expression System: P. pastoris (Yeast)
IL-9 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00025
Species: Human
Expression System: HEK293 Cells
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Cat. No. Product Name Target Signaling Pathways
TMIJ-0209 Beclomethasone-17-Monopropionate-d3

Beclomethasone-17-Monopropionate-d3 是 Beclomethasone-17-Monopropionate 的氘代化合物。Beclomethasone-17-Monopropionate 的 CAS 号为 5534-18-9。
TMIJ-0249 Crisaborole-d4

Crisaborole-d4 是 Crisaborole 的氘代化合物。Crisaborole 的 CAS 号为 906673-24-3。Crisaborole 是一种有效的 PDE4和cytokine释放抑制剂,能够抑制PDE4(IC50=0.49 μM)。
TMIJ-0208 Beclomethasone Dipropionate-d6

Beclomethasone Dipropionate-d6 是 Beclomethasone Dipropionate 的氘代化合物。Beclomethasone Dipropionate 的 CAS 号为 5534-09-8。Betamethasone dipropionate是具有口服活性的糖皮质激素,具有抗炎和免疫抑制作用。它是Betamethasone 的前体药物,Betamethasone 是 LPS 诱导的炎症及 MMP 释放的抑制剂。

同位素标记化合物

Beclomethasone-17-Monopropionate-d3
Cat.No: TMIJ-0209
Synonym:
Target:
Crisaborole-d4
Cat.No: TMIJ-0249
Synonym:
Target:
Beclomethasone Dipropionate-d6
Cat.No: TMIJ-0208
Synonym:
Target:
TargetMol Loading
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