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Anti-IFNL3 Monoclonal Antibody-AF488
产品编号 TMAZ-0008A4
别名 Interferon lambda-3, Interleukin-28C, Cytokine Zcyto22, Interleukin-28B
Anti-IFNL3 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting IFNL3. Anti-IFNL3 Monoclonal Antibody-AF488 can be used in ELISA, FACS.
Anti-IFNL3 Monoclonal Antibody-AF488
Anti-IFNL3 Monoclonal Antibody-AF488
产品编号 TMAZ-0008A4 别名 Interferon lambda-3, Interleukin-28C, Cytokine Zcyto22, Interleukin-28B
Anti-IFNL3 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting IFNL3. Anti-IFNL3 Monoclonal Antibody-AF488 can be used in ELISA, FACS.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μg | ¥ 2,087.42¥ 3,599 | 7日内发货 | |
| 50 μg | ¥ 3,478.84¥ 5,998 | 7日内发货 | |
| 100 μg | ¥ 5,218.26¥ 8,997 | 7日内发货 |
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| 产品描述 | Anti-IFNL3 Monoclonal Antibody-AF488 is a Biotin-conjugated rabbit antibody targeting IFNL3. Anti-IFNL3 Monoclonal Antibody-AF488 can be used in ELISA, FACS. |
| 别名 | Interferon lambda-3, Interleukin-28C, Cytokine Zcyto22, Interleukin-28B |
| Ig Type | Rabbit monoclonal IgG |
| 交叉反应 | Human |
| 验证活性 | Flow cytometry analysis of IFNL3 overexpressed 411F cells with TMAZ-0008A4, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| 应用 | ELISA, FACS |
| 推荐剂量 | 0.1-0.2 μg/10E6 cells for FACS; 1 ng/μl for ELISA |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Secreted |
| 构建方式 | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of IFNL3 protein. |
| 纯化方式 | Protein A Affinity Purified |
| 性状 | Liquid |
| 缓冲液 | 0.22 μm filtered solution in 20 mM HEPES7.4, 150 mM NaCl, 50% glycerol and 0.03% proclin. |
| 纯度 | > 95% as determined by SDS-PAGE. |
| 研究背景 | Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression |
| 偶联 | AF488 |
| 其他可选修饰符 | Biotin/APC/PE/AF555/AF647 |
| 可提供抗体种类 | 1 |
| 免疫原 | IFNL3 |
| 抗原种属 | Human |
| 基因ID | 282617 |
| Uniprot ID | |
| 研究领域 | Immunology Research |
| 分子量 | 150 kDa |
存储&运输
| 储存方式 | For unconjugated and biotin antibody, store at -20°C or -80°C for long term. Avoid repeated freeze-thaw cycles. For APC/PE/AF647/AF555/AF488 conjugated antibody, store at 4°C, do not freeze. |
| 运输方式 | For unconjugated and biotin antibody, shipping with dry ice. For APC/PE/AF647/AF555/AF488 conjugated antibody, shipping with blue ice. |
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