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Search Results for " hepatitis c virus "

161

抑制剂 & 化合物

22

天然产物

1

化合物库

18

重组蛋白

4

同位素标记化合物

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Cat. No.	Product Name
L1720	核苷类化合物库		334 compounds
	334 种核苷类化合物，包括核苷酸、核苷酸类似物及衍生物等，适用于抗病毒、抗肿瘤、抗真菌、抗抑郁等药物的研发；

化合物库

核苷类化合物库

Cat.No: L1720

Compounds: 334

Cat. No.	Product Name	Target	Signaling Pathways
T39503	Hepatitis Virus C NS3 Protease Inhibitor 2
	Hepatitis Virus C NS3 Protease Inhibitor 2 is a peptide inhibitor derived from a product that targets the NS3 protease of the hepatitis C virus (HCV). Its inhibitory activity against the NS3 protease is characterized by a Ki value of 41 nM.
T17190	U18666A	Others; HCV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	U18666A 是一种细胞渗透性药物，是一种胆固醇合成和转运抑制剂，抑制埃博拉病毒，登革热病毒和人类丙型肝炎病毒的复制。
T5938	4-Phenoxybenzylamine	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	4-Phenoxybenzylamine 通过稳定无活性构象来抑制NS3蛋白的功能，对 HCV NS3/4a 的 IC50 约为 500 μM。
T9577	HCV-IN-31	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	HCV-IN-31 是一种HCV 抑制剂，EC50/EC95值为15.7 μM。
T6846	Vesatolimod GS-9620,维沙莫德	Apoptosis; HCV Protease; HBV; TLR; HIV Protease	Apoptosis; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Vesatolimod (GS-9620) 是一种选择性 Toll 样受体 7 口服激动剂，EC50值为291 nM。
T16088	MK-0608	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	MK-0608 是一种可口服的体外 HCV 复制抑制剂。在亚基因组复制子测定中，EC50值为 0.3 μM，EC90值为 1.3 μM。
T25268L	Coblopasvir dihydrochloride Coblopasvir dihydrochloride(1312608-46-0 Free base)	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Coblopasvir dihydrochloride 是一种泛基因型非结构蛋白 5A(NS5A)抑制剂。本品可用于慢性丙型肝炎病毒感染的研究。
T11539	HCV-IN-29	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	HCV-IN-29 是一种丙型肝炎病毒抑制剂。
T15573	Inarigivir soproxil SB9200	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Inarigivir soproxil (SB9200) 是一种先天免疫激动剂。它还显示出针对耐药丙型肝炎病毒 (HCV) 变体的有效抗病毒活性。在基因型 1 HCV 复制子系统细胞中， HCV 1a/1b 的 EC50 为 2.2 和 1.0 μM。
T11541	HCV-IN-30	Others; HCV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	HCV-IN-30 是 HCV NS5A 复制复合物的抑制剂（基因型 1a 和 1b 复制子的 IC50 = 901 和 102 nM）。
T4544	Elbasvir MK-8742	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Elbasvir (MK-8742) 是丙型肝炎病毒的非结构蛋白 5A 抑制剂，可用于治疗慢性 HCV 感染。
T38237	2′-O-Methylcytidine	Nucleoside Antimetabolite/Analog; HCV Protease	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	2'-O-Methylcytidine 是 2'-代核苷，可抑制 HCV 复制。它在体外抑制 NS5B 催化的 RNA 合成，其抑制方式是与底物核苷三磷酸竞争。
T7215	NM107 NM-107,2'-C-甲基胞嘧啶核苷,2'-C-Methylcytidine	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	NM107 (2'-C-Methylcytidine) 是一种具有广谱抗病毒活性的核糖核苷，是丙型肝炎病毒 NS5B 聚合酶的核苷抑制剂，在野生型复制子细胞中的 EC50 为 1.85 μM。
T3444	Merimepodib 美泊地布,VX-497,VI-21497	Dehydrogenase; Antiviral; HCV Protease; HBV	Immunology/Inflammation; Metabolism; Microbiology/Virology; Proteases/Proteasome
	Merimepodib (VX-497) 是一种新型非竞争性肌苷一磷酸脱氢酶抑制剂，具有广谱抗病毒活性。
T1565	Deferiprone 去铁酮,Deferidone,CP20	Others; HCV Protease; Ferroptosis; UGT	Apoptosis; Metabolism; Microbiology/Virology; Others; Proteases/Proteasome
	Deferiprone (Deferidone) 是口服活性铁螯合剂，可研究地中海贫血中的输血性铁过载。
T0013	Mecarbinate 优多降,Dimecarbine,Dimecarbin,美卡比酯	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Mecarbinate 是一种吲哚衍生物，具有抗 HCV 活性和免疫调节作用。
T7158	Ombitasvir 奥比他韦,ABT-267	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Ombitasvir (ABT-267) 是丙型肝炎病毒非结构蛋白 5A 的口服生物可利用的强效抑制剂。对 HCV 基因型 1 至 5 的 EC50 为 0.82 至 19.3 pM，对基因型 6a 的 EC50 为 366 pM。
T14489	Azvudine 4-氨基-1-(4-C-叠氮基-2-脱氧-2-氟-BETA-D-呋喃阿拉伯糖基)-2(1H)-嘧啶酮,FNC,RO-0622	HCV Protease; HBV; HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Azvudine (FNC) 是一种有效的核苷逆转录酶抑制剂 (NRTI)，对 HIV、HBV 和 HCV 具有抗病毒活性。它抑制耐 NRTI 的病毒株，高效抑制 HIV-1和 HIV-2。
T1822	Clemizole 克立咪唑,吡咯咪唑	HCV Protease; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Clemizole 是一种 H1 组胺受体拮抗剂，可抑制 NS4B 的 RNA 结合和丙型肝炎病毒复制。它也是TRP5通道抑制剂。
T5126	Glecaprevir ABT-493	HCV Protease; SARS-CoV	Microbiology/Virology; Proteases/Proteasome
	Glecaprevir (ABT-493) 是一种新型的 HCV NS3/4A 蛋白酶抑制剂，其 IC50值在 3.5 和 11.3 nM 之间。它也是 SARS-CoV 3CLpro 的抑制剂，IC50为 4.09 μM。
T4547	Grazoprevir MK-5172	HCV Protease; SARS-CoV	Microbiology/Virology; Proteases/Proteasome
	Grazoprevir (MK-5172) 是一种丙型肝炎病毒 NS3/4a 蛋白酶的选择性抑制剂，具有跨基因型和耐药变体的广泛活性，对 gt1b、gt1a、gt2a、gt2b 和 gt3a 的Ki 分别为 0.01 nM、0.01 nM、0.08 nM、0.15 nM 和 0.90 nM。它也是 SARS-CoV-2 3CLpro 抑制剂。
T3334	Velpatasvir GS-5816,维帕他韦	HCV Protease; SARS-CoV	Microbiology/Virology; Proteases/Proteasome
	Velpatasvir (GS-5816) 是一种的 HCV NS5A 抑制剂。它也是 SARS-CoV 3CLpro 的抑制剂，IC50为 2.16 μM。
T6200	Ledipasvir GS-5885,雷迪帕韦	HCV Protease; SARS-CoV	Microbiology/Virology; Proteases/Proteasome
	Ledipasvir (GS-5885) 是一种丙型肝炎病毒 NS5A 抑制剂。它也是 P-糖蛋白抑制剂和乳腺癌抗性蛋白抑制剂。
T9341	Bemnifosbuvir AT-511	Others; HCV Protease; SARS-CoV	Microbiology/Virology; Others; Proteases/Proteasome
	Bemnifosbuvir (AT-511) 是一种口服活性抑制剂，抑制 HCV 病毒复制，具有全基因型抗病毒活性。它有效抑制 SARS-CoV-2 (COVID-19)感染 (EC90=0.47 μM)。
T11760	KIN101 3-(4-Bromophenyl)-7-[(methylsulfonyl)oxy]-4-oxo-4H-chromene,3-(4-溴苯基)-4-氧代-7-[(甲磺酰基)氧基]-4H-色烯	HCV Protease; Influenza Virus; RSV; Antifection	Microbiology/Virology; Proteases/Proteasome
	KIN101 (3-(4-Bromophenyl)-7-[(methylsulfonyl)oxy]-4-oxo-4H-chromene) 是 IRF-3 依赖性信号传导的异黄酮激动剂，可诱导 IRF-3 核易位。它对 RNA 病毒、HCV 和 RSV 具有抗病毒活性。
T11281L	FGI-106 tetrahydrochloride	Virus Protease; HCV Protease; Influenza Virus; HIV Protease	Microbiology/Virology; Proteases/Proteasome
	FGI-106 tetrahydrochloride 对多种病毒具有抑制活性，有抗埃博拉病毒，裂谷病毒和登革热病毒的 EC50分别为 100 nM，800 nM 和 400-900 nM，抑制非失血性发热病毒HCV 和HIV-1的EC50分别为 200 nM 和 150 nM 。
T4474	Asunaprevir BMS-650032,阿那匹韦	HCV Protease; SARS-CoV	Microbiology/Virology; Proteases/Proteasome
	Asunaprevir (BMS-650032) 是一种有口服活性的 HCV NS3 蛋白酶抑制剂，IC50值为 0.2 nM-3.5 nM。它也是 SARS-CoV-2 3CLpro 抑制剂。
TQ0064	Peretinoin NIK333	HCV Protease; Retinoid Receptor; S1P Receptor; Autophagy	Autophagy; GPCR/G Protein; Metabolism; Microbiology/Virology; Proteases/Proteasome
	Peretinoin (NIK333) 是口服非环状类视黄醇，靶向类视黄醇核受体，结构类维生素 A 。
T9331	Bemnifosbuvir hemisulfate AT-527	HCV Protease; SARS-CoV	Microbiology/Virology; Proteases/Proteasome
	Bemnifosbuvir hemisulfate (AT-527) 是一种 HCV 病毒复制抑制剂。
T0684	Ribavirin Tribavirin,ICN-1229,NSC-163039,利巴韦林,RTCA	Dehydrogenase; HCV Protease; DNA/RNA Synthesis; Antibiotic; AChR; RSV	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Ribavirin (Tribavirin) 是一种合成的呋喃核苷类似物，一种抗病毒剂。Ribavirin 具有抗丙型肝炎病毒和其他 RNA 病毒的活性。
T27499	GSK-A1	HCV Protease; PI4K	Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	GSK-A1 是 III 型磷脂酰肌醇 4-激酶 PI4KA 选择性抑制剂，pIC50为 8.5-9.8，抑制 PtdIns(4,5)P2 再合成，IC50约为 3 nM。GSK-A1有效降低 PtdIns(4)P 的水平，而对 PtdIns(4,5)P2 没影响。GSK-A1在抗丙型肝炎病毒方面有研究的潜力。
T1822L	Clemizole hydrochloride 克立咪唑盐酸,盐酸克立咪唑	HCV Protease; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Clemizole hydrochloride 是一种 TRPC5通道的抑制剂。它还是一种 H1 组胺受体拮抗剂，抑制 HCV 复制。
T19073	Tris(4-aminophenyl)methane 4,4’,4"-三氨基三苯甲烷,Leucopararosaniline	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Tris(4-aminophenyl)methane (Leucopararosaniline) 是一种三苯甲烷类染料，是一种 HCV 解旋酶抑制剂。
T3489	Dasabuvir ABT-333,达塞布韦	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Dasabuvir (ABT-333) 是丙型肝炎病毒非结构蛋白 5B 的非核苷抑制剂，是一种 RNA 依赖性 RNA 聚合酶，具有抗 HCV 的潜在活性。
T6676	Sofosbuvir 索非布韦,GS 7977,PSI-7977	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Sofosbuvir (GS 7977) 是一种丙型肝炎病毒聚合酶 NS5B 的尿苷单磷酸类似物抑制剂，用作治疗慢性丙型肝炎的抗病毒剂。
T22142	RO8191 RO4948191,CDM-3008	HCV Protease; HBV; JAK; IFNAR; STAT	Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Microbiology/Virology; Proteases/Proteasome; Stem Cells
	RO8191 (CDM-3008) 是干扰素 (IFN) 受体激动剂。它直接与 IFNα/β 受体 2 结合，激活 IFN 刺激的基因表达和 JAK/STAT 磷酸化。它通过具有干扰素样活性发挥 cccDNA 调节剂作用，并具有抗 HBV 活性。
T8930	CID44216842 KUC103479N-02	CDK; Ras	Cell Cycle/Checkpoint; GPCR/G Protein; MAPK
	CID44216842 (KUC103479N-02) 是Cdc42选择性抑制剂。在 GDP 结合测定中，它对 Cdc42 野生型和 Cdc42Q61L 突变型的EC50分别为 0.3 和 0.5 μM。在 GTP 结合测定中，它对 Cdc42 野生型和 Cdc42Q61L 突变型的EC50分别为 1.0 和 1.2 μM。它可用作分子探针。
T12961	Sofosbuvir impurity F 索非布韦杂质 F,Sofosbuvir 3',5'-Bis-(S)-phosphate	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Sofosbuvir impurity F (Sofosbuvir 3',5'-Bis-(S)-phosphate) 既是 Sofosbuvir 的非对映异构体，也是 Sofosbuvir 的杂质，Sofosbuvir 是 HCV RNA 复制的抑制剂。
T6964	Resiquimod R848,雷西莫特,S28463	HCV Protease; TLR	Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Resiquimod (R848) 是一种 Toll 样受体7/8的激动剂，可诱导细胞因子上调。
T76524	Hepatitis C Virus S5A/5B
	Hepatitis C Virus S5A/5B是一种合成肽底物，模拟非结构蛋白(NS)的NS5A/5B连接，用于研究HCVNS3蛋白酶活性。
T6729	Lomibuvir VX-222,VCH-222	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Lomibuvir (VCH-222) (VX-222) 是丙型肝炎病毒 NS5B 聚合酶的一种非核苷变构抑制剂，Kd 值为 17 nM，已证明具有临床疗效。Lomibuvir 抑制 1b/Con1 型 HCV 亚基因组复制子，EC50为 5.2 nM。Lomibuvir 优先抑制延长的 RNA 合成，而非从头合成的 RNA。
T2117	PSI-6206 2'-deoxy-2'-fluoro-2'-C-methyluridine,RO 2433,GS-331007	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	PSI-6206 (RO 2433) 是 PSI-6130 的脱氨衍生物，PSI-6206 是一种选择性 HCV RNA 聚合酶抑制剂，低效抑制HCV 复制，EC90为 >100 μM。PSI-6130 是一种有效的选择性 HCV NS5B 聚合酶抑制剂。
T4203	Ledipasvir (acetone) Ledipasvir acetone,雷迪帕韦单丙酮溶剂化物,GS-5885 acetone,雷迪帕韦单丙酮	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Ledipasvir (acetone) (GS-5885 acetone) 是 Ledipasvir 的活性药物成分。Ledipasvir 是一种 HCV NS5A 聚合酶抑制剂，用于治疗丙型肝炎病毒感染。
T19840	GSK-F1 PI4KA inhibitor-F1	PI4K	PI3K/Akt/mTOR signaling
	GSK-F1 (PI4KA inhibitor-F1) 是一种新型强效 PI4KA 抑制剂。
T9567	Samatasvir ATOLIHZIXHZSBA-BTSKBWHGSA-N,IDX719	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Samatasvir (ATOLIHZIXHZSBA-BTSKBWHGSA-N) 是 NS5A HCV 复制抑制剂。它能够有效的选择复制子及感染性 HCV，在基因型 1至5 复制子中，EC50= 2~24 pM。
T4988	Boceprevir SCH 503034,EBP 520,波普瑞韦	HCV Protease; SARS-CoV	Microbiology/Virology; Proteases/Proteasome
	Boceprevir (SCH 503034) 是一种口服有效的选择性 HCV NS3 蛋白酶抑制剂。在酶试验中的 Ki 为 14 nM，在基于细胞的复制子试验中 EC90 为 350 nM。它也是 SARS-CoV-2 3CLpro 抑制剂。
T4686	Simeprevir TMC435,西咪匹韦,TMC-435350,Olysio	HCV Protease; SARS-CoV	Microbiology/Virology; Proteases/Proteasome
	Simeprevir (TMC435) 是一种有效的 HCV NS3/4A 蛋白酶抑制剂，抑制 HCV 复制，EC50 为 7.8 nM。它也是 SARS-CoV-2 3CLpro 抑制剂。
T14667	BLT-1	Others; HCV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	BLT-1 是一种氨基硫脲铜螯合剂，是一种选择性清除受体 B1 型 (SR-BI) 抑制剂，抑制高密度脂蛋白 (HDL) 和 SR-BI 介导的细胞之间的脂质转移。
T22394	Paritaprevir ABT450,ABT-450,帕利普韦,Veruprevir	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Paritaprevir (ABT450) 是一种非结构蛋白 3/4A 蛋白酶抑制剂，对 HCV 1a 和 HCV 1b 的 EC50 值分别为 1 和 0.21 nM。它也是SARS-CoV 3CLpro 的抑制剂，IC50为 1.31 μM。
T25268	Coblopasvir	Others	Others
	Coblopasvir 是一种泛基因型非结构蛋白5A(NS5A)抑制剂。它可以用于研究慢性丙型肝炎病毒的感染。

化合物

Hepatitis Virus C NS3 Protease Inhibitor 2

Cat.No: T39503

Cat.No: T17190

Target: Others, HCV Protease

4-Phenoxybenzylamine

Cat.No: T5938

Target: HCV Protease

Cat.No: T9577

Target: HCV Protease

Cat.No: T6846

Synonym: GS-9620,维沙莫德

Target: Apoptosis, HCV Protease, HBV, TLR, HIV Protease

Cat.No: T16088

Target: HCV Protease

Coblopasvir dihydrochloride

Cat.No: T25268L

Synonym: Coblopasvir dihydrochloride(1312608-46-0 Free base)

Target: HCV Protease

Cat.No: T11539

Target: HCV Protease

Inarigivir soproxil

Cat.No: T15573

Synonym: SB9200

Target: HCV Protease

Cat.No: T11541

Target: Others, HCV Protease

Cat.No: T4544

Synonym: MK-8742

Target: HCV Protease

2′-O-Methylcytidine

Cat.No: T38237

Target: Nucleoside Antimetabolite/Analog, HCV Protease

Cat.No: T7215

Synonym: NM-107,2'-C-甲基胞嘧啶核苷,2'-C-Methylcytidine

Target: HCV Protease

Cat.No: T3444

Synonym: 美泊地布,VX-497,VI-21497

Target: Dehydrogenase, Antiviral, HCV Protease, HBV

Cat.No: T1565

Synonym: 去铁酮,Deferidone,CP20

Target: Others, HCV Protease, Ferroptosis, UGT

Cat.No: T0013

Synonym: 优多降,Dimecarbine,Dimecarbin,美卡比酯

Target: HCV Protease

Cat.No: T7158

Synonym: 奥比他韦,ABT-267

Target: HCV Protease

Cat.No: T14489

Synonym: 4-氨基-1-(4-C-叠氮基-2-脱氧-2-氟-BETA-D-呋喃阿拉伯糖基)-2(1H)-嘧啶酮,FNC,RO-0622

Target: HCV Protease, HBV, HIV Protease, Reverse Transcriptase

Cat.No: T1822

Synonym: 克立咪唑,吡咯咪唑

Target: HCV Protease, Histamine Receptor

Cat.No: T5126

Synonym: ABT-493

Target: HCV Protease, SARS-CoV

Cat.No: T4547

Synonym: MK-5172

Target: HCV Protease, SARS-CoV

Cat.No: T3334

Synonym: GS-5816,维帕他韦

Target: HCV Protease, SARS-CoV

Cat.No: T6200

Synonym: GS-5885,雷迪帕韦

Target: HCV Protease, SARS-CoV

Cat.No: T9341

Synonym: AT-511

Target: Others, HCV Protease, SARS-CoV

Cat.No: T11760

Synonym: 3-(4-Bromophenyl)-7-[(methylsulfonyl)oxy]-4-oxo-4H-chromene,3-(4-溴苯基)-4-氧代-7-[(甲磺酰基)氧基]-4H-色烯

Target: HCV Protease, Influenza Virus, RSV, Antifection

FGI-106 tetrahydrochloride

Cat.No: T11281L

Target: Virus Protease, HCV Protease, Influenza Virus, HIV Protease

Cat.No: T4474

Synonym: BMS-650032,阿那匹韦

Target: HCV Protease, SARS-CoV

Cat.No: TQ0064

Synonym: NIK333

Target: HCV Protease, Retinoid Receptor, S1P Receptor, Autophagy

Bemnifosbuvir hemisulfate

Cat.No: T9331

Synonym: AT-527

Target: HCV Protease, SARS-CoV

Cat.No: T0684

Synonym: Tribavirin,ICN-1229,NSC-163039,利巴韦林,RTCA

Target: Dehydrogenase, HCV Protease, DNA/RNA Synthesis, Antibiotic, AChR, RSV

Cat.No: T27499

Target: HCV Protease, PI4K

Clemizole hydrochloride

Cat.No: T1822L

Synonym: 克立咪唑盐酸,盐酸克立咪唑

Target: HCV Protease, Histamine Receptor

Tris(4-aminophenyl)methane

Cat.No: T19073

Synonym: 4,4’,4"-三氨基三苯甲烷,Leucopararosaniline

Target: HCV Protease

Cat.No: T3489

Synonym: ABT-333,达塞布韦

Target: HCV Protease

Cat.No: T6676

Synonym: 索非布韦,GS 7977,PSI-7977

Target: HCV Protease

Cat.No: T22142

Synonym: RO4948191,CDM-3008

Target: HCV Protease, HBV, JAK, IFNAR, STAT

Cat.No: T8930

Synonym: KUC103479N-02

Target: CDK, Ras

Sofosbuvir impurity F

Cat.No: T12961

Synonym: 索非布韦杂质 F,Sofosbuvir 3',5'-Bis-(S)-phosphate

Target: HCV Protease

Cat.No: T6964

Synonym: R848,雷西莫特,S28463

Target: HCV Protease, TLR

Hepatitis C Virus S5A/5B

Cat.No: T76524

Cat.No: T6729

Synonym: VX-222,VCH-222

Target: HCV Protease

Cat.No: T2117

Synonym: 2'-deoxy-2'-fluoro-2'-C-methyluridine,RO 2433,GS-331007

Target: HCV Protease

Ledipasvir (acetone)

Cat.No: T4203

Synonym: Ledipasvir acetone,雷迪帕韦单丙酮溶剂化物,GS-5885 acetone,雷迪帕韦单丙酮

Target: HCV Protease

Cat.No: T19840

Synonym: PI4KA inhibitor-F1

Target: PI4K

Cat.No: T9567

Synonym: ATOLIHZIXHZSBA-BTSKBWHGSA-N,IDX719

Target: HCV Protease

Cat.No: T4988

Synonym: SCH 503034,EBP 520,波普瑞韦

Target: HCV Protease, SARS-CoV

Cat.No: T4686

Synonym: TMC435,西咪匹韦,TMC-435350,Olysio

Target: HCV Protease, SARS-CoV

Cat.No: T14667

Target: Others, HCV Protease

Cat.No: T22394

Synonym: ABT450,ABT-450,帕利普韦,Veruprevir

Target: HCV Protease

Cat.No: T25268

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T5S1598	Mulberroside C 桑皮苷 C,桑皮苷C	Antioxidant; HCV Protease	Microbiology/Virology; oxidation-reduction; Proteases/Proteasome
	Mulberroside C 是桑树中的主要生物活性成分之一，可抑制 HCV 复制，具有抗病毒活性。
T3273	Bifendate 联苯双酯,Bifendatatum	HBV; Reverse Transcriptase	Microbiology/Virology
	Bifendate (Bifendatatum) 是 Schisandrin C 的合成中间体，在慢性 B 型肝炎的研究中具有抗HBV 功效，用于治疗病毒性肝炎和药物性肝损伤引起的转氨酶升高。
T2770	Gentiopicroside Gentiopicrin,龙胆苦甙,龙胆苦苷	P450; HCV Protease	Metabolism; Microbiology/Virology; Proteases/Proteasome
	Gentiopicroside (Gentiopicrin) 是天然环烯醚萜苷，具有抗炎和抗氧化活性。它抑制P450的活性，对 CYP2A6 的 IC50和 Ki 值分别为 61 µM 和 22.8 µM，
TN2089	Platycodin D3 桔梗皂苷D3,桔梗皂苷 D3	HCV Protease; NF-κB	Microbiology/Virology; NF-κB; Proteases/Proteasome
	Platycodin D3 是桔梗中有抗HCV 活性的一种三萜皂苷类天然产物。
T3810	Saikosaponin B2 柴胡皂苷 B2,柴胡皂甙 B2	Others; HCV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	Saikosaponin B2 是从柴胡根中分离得到的一种活性成分，可抑制 HCV 病毒感染的侵入，有抗癌作用。
T7607	PSI-6130 R 1656,2'-去氧-2'-氟-2'-C-甲基胞苷	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	PSI-6130 (R 1656) 是高效选择性 HCV NS5B 聚合酶抑制剂，抑制 HCV 复制，IC50值为 0.6 μM。
T3001	Honokiol 和厚朴酚,NSC 293100	ERK; HCV Protease; MEK; Akt; Autophagy	Autophagy; Cytoskeletal Signaling; MAPK; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Honokiol (NSC-293100) 是厚朴提取物的活性成分，靶向多种信号分子，具有抗氧化，抗炎，抗血管生成和抗癌活性。它可抑制 Akt 的激活并增强 ERK1/ERK2 的磷酸化。
T3821	Deapioplatycodin D Deapi-platycodin D,去芹糖桔梗皂苷 D,去芹糖桔梗皂苷D,DesapioplatycodinD	Others; HCV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	Deapioplatycodin D 是从桔梗中分离出的一种三萜皂苷，具有抗丙型肝炎病毒活性。
T2S1158	4,5-Dicaffeoylquinic acid 3,4-Dicaffeoylquinic acid,异绿原酸C(4,5),Isochlorogenic acid C	Others; HBV; Endogenous Metabolite	Metabolism; Microbiology/Virology; Others
	4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) 是一种天然产物，有抗病毒、抗肝毒性活性。
T0392	Artemisinin Qinghaosu,Artemisinine,Qinghaosu,NSC 369397,青蒿素,Artemisinine	HCV Protease; Ferroptosis; Akt; Parasite	Apoptosis; Cytoskeletal Signaling; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Artemisinin (Qinghaosu) 是一种倍半萜烯内酯，是从青蒿植物的地上部分分离的一种抗疟疾药物。它有神经保护和抗癌作用。
T1188	Mizoribine Bredinin,NSC 289637,咪唑立宾,HE 69	HCV Protease; SARS-CoV; Tyrosinase	Microbiology/Virology; Proteases/Proteasome
	Mizoribine (NSC-289637) 是一种免疫抑制剂，抑制HCVRNA 复制，有抗 HCV 活性，IC50约为 100 μM。它抑制SARS-CoV 复制，对 SARS-CoV Frankfurt-1 和 SARS-CoV HKU39849 的 IC50分别为 3.5 μg/mL 和 16 μg/mL。
T7203	Oglufanide 奥谷法奈,L-Glutamyl-L-tryptophan,H-Glu-Trp-OH	VEGFR; HCV Protease; Endogenous Metabolite	Angiogenesis; Metabolism; Microbiology/Virology; Proteases/Proteasome; Tyrosine Kinase/Adaptors
	Oglufanide (H-Glu-Trp-OH) 是一种从小牛胸腺中分离出来的二肽免疫调节剂，可抑制血管内皮生长因子，可刺激细胞内细菌感染和对丙型肝炎病毒的免疫反应。
T7060	Amantadine 1-Aminoadamantane,1-金刚烷胺,金刚烷胺,1-Adamantanamine,1-Adamantylamine	Others	Others
	Amantadine (1-Aminoadamantane) 是抗病毒药物，也是是 NMDA 型谷氨酸受体的弱拮抗剂，能促进高多巴胺的释放，并阻断多巴胺的再摄取。
TN1033	Sennidin A	HCV Protease; transporter; Akt; PI3K	Cytoskeletal Signaling; Metabolism; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Sennidin A 是从狭叶番泻分离得到的一种天然产物，能够抑制 HCV NS3 解旋酶，其 IC50值为0.8 μM。它诱导 Akt 和葡萄糖转运蛋白4的磷酸化，刺激葡萄糖掺入。
TN1034	Sennidin B	HCV Protease; transporter; Akt; PI3K	Cytoskeletal Signaling; Metabolism; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Sennidin B 是从Cassia angustifolia 分离得到的Sennidin A 异构体，它刺激葡萄糖掺入，诱导Akt 和葡萄糖转运蛋白4 的磷酸化。
TN6732	Oenothein B	Apoptosis; HCV Protease; Antibacterial; Antifungal	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Oenothein B 是一种聚（ADP-核糖）糖水解酶的特异性抑制剂。 Oenothein B 具有抗氧化、抗炎、抗真菌、抗 HCV 和抗肿瘤特性。
T38375	Pseudane IX 2-nonyl-4-hydroxyquinoline,2-nonyl-1H-quinolin-4-one,2-nonyl-4(1h)-quinolone	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Pseudane IX (2-nonyl-1H-quinolin-4-one) 可减少丙型肝炎病毒 (HCV) 对 Huh 7.5 细胞的感染，IC50 为 1.4 μg/ml。
TN2185	Schisantherin C	Others	Others
	Schisantherin A, B, C, and D show good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis.
TN5079	Sulochrin	HCV Protease; Antifection	Microbiology/Virology; Proteases/Proteasome
	Sulochrin shows antifungal and antibacterial activities, it can inhibit hepatitis C virus (HCV) infection in a dose-dependent manner without any apparent cytotoxicity up to 50 uM. Sulochrin has an inhibitory activity to eosinophil degranulation.
TN3809	Dehydrojuncusol	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Dehydrojuncusol, a new inhibitor of hepatitis C virus RNA replication, it inhibits infection of different HCV genotypes by targeting the NS5A protein and is active against resistant HCV variants frequently found in patients with treatment failure.
TN4404	Ladanein	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Ladanein is a phytochemicals inhibitor that is known to disrupt the interactions of core and other hepatitis C virus (HCV) proteins.Ladanein possesses free radicals DPPH and ABTS +.scavenging activity, it also displays moderate (20-40 microM) activities against K562, K562R (imatinib-resistant), and 697 human leukemia cell lines.
TN3438	Arborinine	HCV Protease; Antifection	Microbiology/Virology; Proteases/Proteasome
	Arborinine shows mild in vitro antibacterial activity, it possesses moderate levels of anti-hepatitis C virus(HCV) activities with the IC50 values being 6.4 ± 0.7 ug/ml. Arborinine shows antifeedant activity against Spodoptera frugiperda. Arborinin shows

天然产物

Cat.No: T5S1598

Synonym: 桑皮苷 C,桑皮苷C

Target: Antioxidant, HCV Protease

Cat.No: T3273

Synonym: 联苯双酯,Bifendatatum

Target: HBV, Reverse Transcriptase

Gentiopicroside

Cat.No: T2770

Synonym: Gentiopicrin,龙胆苦甙,龙胆苦苷

Target: P450, HCV Protease

Cat.No: TN2089

Synonym: 桔梗皂苷D3,桔梗皂苷 D3

Target: HCV Protease, NF-κB

Saikosaponin B2

Cat.No: T3810

Synonym: 柴胡皂苷 B2,柴胡皂甙 B2

Target: Others, HCV Protease

Cat.No: T7607

Synonym: R 1656,2'-去氧-2'-氟-2'-C-甲基胞苷

Target: HCV Protease

Cat.No: T3001

Synonym: 和厚朴酚,NSC 293100

Target: ERK, HCV Protease, MEK, Akt, Autophagy

Deapioplatycodin D

Cat.No: T3821

Synonym: Deapi-platycodin D,去芹糖桔梗皂苷 D,去芹糖桔梗皂苷D,DesapioplatycodinD

Target: Others, HCV Protease

4,5-Dicaffeoylquinic acid

Cat.No: T2S1158

Synonym: 3,4-Dicaffeoylquinic acid,异绿原酸C(4,5),Isochlorogenic acid C

Target: Others, HBV, Endogenous Metabolite

Cat.No: T0392

Synonym: Qinghaosu,Artemisinine,Qinghaosu,NSC 369397,青蒿素,Artemisinine

Target: HCV Protease, Ferroptosis, Akt, Parasite

Cat.No: T1188

Synonym: Bredinin,NSC 289637,咪唑立宾,HE 69

Target: HCV Protease, SARS-CoV, Tyrosinase

Cat.No: T7203

Synonym: 奥谷法奈,L-Glutamyl-L-tryptophan,H-Glu-Trp-OH

Target: VEGFR, HCV Protease, Endogenous Metabolite

Cat.No: T7060

Synonym: 1-Aminoadamantane,1-金刚烷胺,金刚烷胺,1-Adamantanamine,1-Adamantylamine

Target: Others

Cat.No: TN1033

Target: HCV Protease, transporter, Akt, PI3K

Cat.No: TN1034

Target: HCV Protease, transporter, Akt, PI3K

Cat.No: TN6732

Target: Apoptosis, HCV Protease, Antibacterial, Antifungal

Cat.No: T38375

Synonym: 2-nonyl-4-hydroxyquinoline,2-nonyl-1H-quinolin-4-one,2-nonyl-4(1h)-quinolone

Target: HCV Protease

Schisantherin C

Cat.No: TN2185

Target: Others

Cat.No: TN5079

Target: HCV Protease, Antifection

Dehydrojuncusol

Cat.No: TN3809

Target: HCV Protease

Cat.No: TN4404

Target: HCV Protease

Cat.No: TN3438

Target: HCV Protease, Antifection

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01564	Hepatitis C virus (HCV-1a) E2 Protein (His) HCV-1a E2	HCV	HEK293 Cells
	Hepatitis C virus (HCV-1a) E2 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32 kDa and the accession number is NP_751921.1.
TMPY-00296	Hepatitis C virus (HCV) (serotype 1c,isolate HC-G9) E2 Protein (His) HCV-1a E2	HCV	HEK293 Cells
	Hepatitis C virus (HCV) (serotype 1c,isolate HC-G9) E2 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.2 kDa and the accession number is BAA03581.1.
TMPY-05166	Hepatitis C virus (HCV) (serotype 1b, isolate HC-J4) Envelope/E2 Protein (His) HCV-1a E2	HCV	HEK293 Cells
	Hepatitis C virus (HCV) (serotype 1b, isolate HC-J4) Envelope/E2 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.4 kDa and the accession number is AAC15723.1.
TMPY-00323	Hepatitis C virus (HCV-1a) NS3 protease/helicase immunodominant region Protein (aa 1356-1459, GST) NS3	HCV	E. coli
	HCV NS3 displays three enzymatic activities: serine protease, NTPase, and RNA helicase. HCV NS3 serine protease, in association with NS4A, is responsible for the cleavages of NS3-NS4A, NS4A-NS4B, NS4B-NS5A, and NS5A-NS5B. HCV NS3 RNA helicase binds to RNA and unwinds dsRNA in the 3' to 5' direction, and likely RNA stable secondary structure in the template strand (By similarity). Cleaves and inhibits the host antiviral protein MAVS. NS3/NS4A complex also prevents phosphorylation of human IRF3, t...
TMPJ-01273	ACY3 Protein, Human, Recombinant (His) Acylase III,Aminoacylase-3,ACY3,<...	Human	E. coli
	Aspartoacylase 3, also known as ACY3, N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming), Acylase III, Aminoacylase-3, Aspartoacylase-2, Aspartoacylase-2, HCV core-binding protein 1 and ASPA2, is a member of the Aspartoacylase subfamily. ACY3 plays an important role in deacetylating mercapturic acids in kidney proximal tubules and acts on N-acetyl-aromatic amino acids.ACY3 is located in the cytoplasm of S2 and S3 proximal tubules and the apical domain of S1 proximal tubules. ACY3 ...
TMPY-04135	Hepatitis C virus Envelope Glycoprotein E1/HCV-E1 (subtype 1b, strain HC-J4) Protein (His) HCV-E1	HCV	HEK293 Cells
	Hepatitis C virus Envelope Glycoprotein E1/HCV-E1 (subtype 1b, strain HC-J4) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.7 kDa and the accession number is AAC15725.1.
TMPH-00810	Hepatitis delta virus genotype I (HDV) Large delta antigen Protein (His & Myc) p27,Large delta antigen	HDV	P. pastoris (Yeast)
	Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal. Needs co-infection with hepatitis B virus to provide surface proteins, otherwise there is no packaging or budding. Packages the HDV ribonucleoprotein in hepatitis B virus empty particles. Interacts with both HDV genomic RNA and cytoplasmic tail of HBsAg. May inhibit viral RNA replication. Hepatitis delta virus genotype I (HDV) Large delta antigen Protein (His & Myc) is expressed i...
TMPY-02285	Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS2 Protein NS2 Protein	H1N1	E. coli
	Non-structural protein 2 (NS2) plays a crucial role in the hepatitis C virus (HCV) assembly. NS2 was predicted to be composed of three transmembrane (TM) segments. Hepatitis C virus (HCV) nonstructural protein 2 (NS2) is a hydrophobic, transmembrane protein that is required not only for NS2-NS3 cleavage but also for infectious virus production.NS2 protein is essential for hepatitis C virus (HCV) replication. NS2 protein was expressed and purified. Aptamers against NS2 protein were raised and ant...
TMPH-01548	IFI6 Protein, Human, Recombinant (B2M & His) Interferon-induced protein 6-16,IFI6,Interferon alp...	Human	E. coli
	Plays a role in apoptosis, negatively regulating the intrinsinc apoptotic signaling pathway and TNFSF10-induced apoptosis. However, it has also been shown to have a pro-apoptotic activity. Has an antiviral activity towards hepatitis C virus/HCV by inhibiting the EGFR signaling pathway, which activation is required for entry of the virus into cells.
TMPH-01104	Claudin-9 Protein-VLP, Human, Recombinant (His) CLDN9,Claudin-9	Human	HEK293 Cells
	Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.; (Microbial infection) Acts as a receptor for hepatitis C virus (HCV) entry into hepatic cells. Claudin-9 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-10xHis tag. The predicted molecular weight is 24.2 kDa and the accession number is O95484.
TMPH-00848	OASL Protein, Human, Recombinant (His) 59 kDa 2'-5'-oligoadenylate synthase-like protein,Thyroid re...	Human	E. coli
	Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L. OASL Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 65.1 kDa and the accession number is Q15646.
TMPH-01902	DDX60 Protein, Human, Recombinant (His) Probable ATP-dependent RNA helicase DDX60,DEAD box ...	Human	E. coli
	Positively regulates DDX58/RIG-I- and IFIH1/MDA5-dependent type I interferon and interferon inducible gene expression in response to viral infection. Binds ssRNA, dsRNA and dsDNA and can promote the binding of DDX58/RIG-I to dsRNA. Exhibits antiviral activity against hepatitis C virus and vesicular stomatitis virus (VSV). DDX60 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.1 kDa and the accession number is Q8IY2...
TMPH-00811	Hepatitis delta virus genotype I (HDV) Small delta antigen Protein (His & Myc) Small delta antigen,p24	HDV	P. pastoris (Yeast)
	Promotes both transcription and replication of genomic RNA. Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal. May interact with host RNA polymerase II thereby changing its template requirement from DNA to RNA. RNA pol II complex would then acts as an RNA-directed RNA polymerase, and transcribe and replicate HDV genome. Hepatitis delta virus genotype I (HDV) Small delta antigen Protein (His & Myc) is expressed in yeast with N-6xHi...
TMPH-02131	SKP2 Protein, Human, Recombinant (His & SUMO) S-phase kinase-associated protein 2,SKP2,F-box prot...	Human	E. coli
	Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. Degradation of CDKN1B/p27kip also requires CKS1. Recognizes target proteins ORC1, CDT1, RBL2, KMT2A/MLL1, CDK9, RAG2, FOXO1, UB...
TMPH-01248	ADAR Protein, Human, Recombinant (His & SUMO) ADAR1,IFI-4,136 kDa double-stranded RNA-binding protein,Inte...	Human	E. coli
	Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translation by changing codons and hence the amino acid sequence of proteins; pre-mRNA splicing by altering splice site recognition sequences; RNA stability by changing sequences involved in nuclease recognition; genetic stability in the case of RNA virus genomes by changing sequences duri...
TMPK-01450	HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated KRAS1,MHC,K-RAS4B,KRAS,CFC2,K-RAS...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01456	HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi) KRAS2,NS,MHC,C-K-RAS,KRAS1,K-RAS2A,K-RAS2B...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01451	HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi) NS3,K-RAS4A,K-Ras 2,NS,KRAS1,RASK2,MHC,KI-RAS,KRAS,...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.

重组蛋白

Hepatitis C virus (HCV-1a) E2 Protein (His)

Cat.No: TMPY-01564

Species: HCV

Expression System: HEK293 Cells

Hepatitis C virus (HCV) (serotype 1c,isolate HC-G9) E2 Protein (His)

Cat.No: TMPY-00296

Species: HCV

Expression System: HEK293 Cells

Hepatitis C virus (HCV) (serotype 1b, isolate HC-J4) Envelope/E2 Protein (His)

Cat.No: TMPY-05166

Species: HCV

Expression System: HEK293 Cells

Hepatitis C virus (HCV-1a) NS3 protease/helicase immunodominant region Protein (aa 1356-1459, GST)

Cat.No: TMPY-00323

Species: HCV

Expression System: E. coli

ACY3 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01273

Species: Human

Expression System: E. coli

Hepatitis C virus Envelope Glycoprotein E1/HCV-E1 (subtype 1b, strain HC-J4) Protein (His)

Cat.No: TMPY-04135

Species: HCV

Expression System: HEK293 Cells

Hepatitis delta virus genotype I (HDV) Large delta antigen Protein (His & Myc)

Cat.No: TMPH-00810

Species: HDV

Expression System: P. pastoris (Yeast)

Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS2 Protein

Cat.No: TMPY-02285

Species: H1N1

Expression System: E. coli

IFI6 Protein, Human, Recombinant (B2M & His)

Cat.No: TMPH-01548

Species: Human

Expression System: E. coli

Claudin-9 Protein-VLP, Human, Recombinant (His)

Cat.No: TMPH-01104

Species: Human

Expression System: HEK293 Cells

OASL Protein, Human, Recombinant (His)

Cat.No: TMPH-00848

Species: Human

Expression System: E. coli

DDX60 Protein, Human, Recombinant (His)

Cat.No: TMPH-01902

Species: Human

Expression System: E. coli

Hepatitis delta virus genotype I (HDV) Small delta antigen Protein (His & Myc)

Cat.No: TMPH-00811

Species: HDV

Expression System: P. pastoris (Yeast)

SKP2 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02131

Species: Human

Expression System: E. coli

ADAR Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01248

Species: Human

Expression System: E. coli

HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01450

Species: Human

Expression System: HEK293 Cells

HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01456

Species: Human

Expression System: HEK293 Cells

HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01451

Species: Human

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
T12955	Sofosbuvir D6 PSI-7977 D6,GS-7977 D6	Others	Others
	Sofosbuvir D6 is the deuterium labeled Sofosbuvir. Sofosbuvir is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.
TMIH-0524	Sofosbuvir-13C-d3
	Sofosbuvir-13C-d3 是 Sofosbuvir 的 13C 和氘代化合物。Sofosbuvir 的 CAS 号为 1190307-88-0。Sofosbuvir 是一种丙型肝炎病毒聚合酶 NS5B 的尿苷单磷酸类似物抑制剂，用作治疗慢性丙型肝炎的抗病毒剂。
TMIH-0297	Ledipasvir-d6
	Ledipasvir-d6 是 Ledipasvir 的氘代化合物。Ledipasvir 的 CAS 号为 1256388-51-8。Ledipasvir 是一种丙型肝炎病毒 NS5A 抑制剂。它也是 P-糖蛋白抑制剂和乳腺癌抗性蛋白抑制剂。
T38297	Ribavirin-13C5 Ribavirin-13C5
	Ribavirin-13C5is intended for use as an internal standard for the quantification of ribavirin by GC- or LC-MS. Ribavirin is an antiviral guanosine nucleoside analog.1,2Upon entry into cells, ribavirin is metabolized to an active triphosphate form that induces viral RNA chain termination and inhibits viral polymerases. It reduces replication in a panel of seven RNA and four DNA viruses in Vero cells (EC50s = 2-95 μg/ml).3Ribavirin also reduces replication of severe acute respiratory syndrome coro...

同位素标记化合物

Cat.No: T12955

Synonym: PSI-7977 D6,GS-7977 D6

Target: Others

Sofosbuvir-13C-d3

Cat.No: TMIH-0524

Cat.No: TMIH-0297

Cat.No: T38297

Synonym: Ribavirin-13C5

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