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141
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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T14954 |
Chlorthal-dimethyl
Dimethyl tetrachloroterephthalate |
Others | Others |
Chlorthal-dimethyl用作农药中间体。 | |||
T5988 |
Dimethyl biphenyl-4,4'-dicarboxylate
Biphenyl dimethyl dicarboxylate,联苯二甲酸二甲酯 |
Others | Others |
Dimethyl biphenyl-4,4'-dicarboxylate (Biphenyl dimethyl dicarboxylate) 是一种保肝剂,提取自五味子中,能够诱导 IFN 相关的信号转导。 | |||
T5696 |
Dimethyl succinate
|
Others | Others |
Dimethyl succinate 存在于坚果中。琥珀酸二甲酯存在于烤榛子中。琥珀酸二甲酯是一种调味成分。 | |||
T5377 |
Dimethyl itaconate
|
Others | Others |
Dimethyl itaconate 是一种化学试剂,用于合成功能化 2-异恶唑啉,用于基于片段的药物发现。 | |||
T4239 |
1,3-dimethyl-2-oxobenzimidazole-5-carbaldehyde
1,3-DIMETHYL-2-OXO-2,3-DIHYDRO-1H-BENZIMIDAZOLE-5-CARBALDEHYDE |
Others | Others |
1,3-dimethyl-2-oxobenzimidazole-5-carbaldehyde 是中间体。 | |||
T22309 |
2,5-Dimethyl-3(2H)-furanone
2,5-二甲基-3(2H)-呋喃酮,2,5-Dimethyl-2,3-dihydrofuran-3-one |
Others | Others |
2,5-Dimethyl-3(2H)-furanone (2,5-Dimethyl-2,3-dihydrofuran-3-one) 是一种调味物质,无遗传毒性。 | |||
T7658 |
Dimethyl DL-Glutamate (hydrochloride)
|
Others | Others |
Dimethyl DL-Glutamate (hydrochloride) 是一种细胞渗透性谷氨酸衍生物,可在孤立的胰岛和糖尿病动物模型中增强胰岛素释放以响应葡萄糖。 | |||
T0341 |
Dimethyl sulfoxide
Methyl Sulfoxide,DMSO,二甲基亚砜 |
Others; Antibacterial | Microbiology/Virology; Others |
Dimethyl sulfoxide (DMSO) 是一种常用的溶剂,可溶解极性和非极性化合物。Dimethyl sulfoxide 已被广泛用于生物实验中化合物的母液配制。Dimethyl sulfoxide 具有抑菌活性。 | |||
T35610 |
2,5-dimethyl Celecoxib
|
Apoptosis; Wnt/beta-catenin; Prostaglandin Receptor | Apoptosis; Cytoskeletal Signaling; GPCR/G Protein; Immunology/Inflammation; Stem Cells |
2,5-dimethyl Celecoxib 是塞来昔布衍生物和微粒体前列腺素 E 合酶 1 (mPGES-1) 的靶向抑制剂,mPGES-1 是炎症介质 PGE2 合成途径中的关键酶。 | |||
T50075 |
3,5-dimethyl-4-phenyl-1,2-oxazole
|
Others | Others |
3,5-dimethyl-4-phenyl-1,2-oxazole 是一种用作分子结构单元的杂环化合物,具有抗炎、抗肿瘤、抗细菌和抗真菌活性,以及调节免疫系统的能力。 | |||
T21546 |
NG,NG-dimethyl-L-Arginine dihydrochloride
|
NO Synthase | Immunology/Inflammation |
NG,NG-dimethyl-L-Arginine dihydrochloride 是一种内源性一氧化氮合酶抑制剂。由 L-精氨酸合成的一氧化氮 (NO) 有助于调节血压和宿主防御。 | |||
T72030 |
6,6'-Dimethyl-2,2'-dipyridyl
6,6'-Bi-2-picoline |
Others | Others |
6,6'-Dimethyl-2,2'-dipyridyl (6,6'-Bi-2-picoline) 是一种新型的时间分辨荧光免疫分析(TRFIA)螯合物,具有较好的杀菌效果,可用于研究酒渣鼻。 | |||
T27177 |
Dimethyl ceanothate
dimethyl emmolate |
Others | Others |
Dimethyl ceanothate shows moderate to low leishmanicidal and trypanocidal activities. | |||
T72460 |
Dimethyl L-glutamate
Dimethyl glutamate |
||
Dimethyl L-glutamate (Dimethyl glutamate), 一种可透膜的谷氨酸类似物,可刺激葡萄糖诱导的胰岛素 (insulin) 释放。Dimethyl L-glutamate 抑制KATP 通道的活性。Dimethyl L-glutamate 抑制E. gracilis 生长并导致细胞异常分裂。Dimethyl L-glutamate 可用于糖尿病、葡萄糖转运、磷酸化和进一步代谢的研究。 | |||
T38111 |
Dimethyl-W84 (dibromide)
Dimethyl-W84 (dibromide) |
Others | Others |
Dimethyl-W84 is a selective allosteric modulator of the M2 muscarinic acetylcholine receptor. It hinders the dissociation of the orthosteric antagonist N-methylscopolamine from the M2 receptor with an EC50 value of 3 nM. | |||
T77568 |
6,7-dimethylisatin
6,7-dimethyl-1H-indole-2,3-dione |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) 对 hGAT3 的抑制效力为108μM,对 hBGT1,hGAT2 也具有抑制作用。 | |||
T0874 |
Dimetridazole
1, 2-Dimethyl-5-nitroimidazole,1,2-Dimethyl-5-nitroimidazole,二甲硝咪唑 |
Antibiotic; Parasite | Microbiology/Virology |
Dimetridazole (1, 2-Dimethyl-5-nitroimidazole) 是一种对抗原生动物感染的硝基咪唑类药物。 | |||
Fr14565 |
2,4-DIMETHYLTHIAZOLE
2,4-Dimethyl-1,3-thiazole |
Others | Others |
Compound Fr14565 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 Fr14565,CAS号为 541-58-2。 | |||
T71961 |
TUN-92046
DM-α-KG,T71961,Dimethyl 2-ketoglutarate,Dimethyl 2-oxoglutarate |
Others | Others |
TUN-92046 (Dimethyl 2-oxoglutarate)是一种膜渗透性α酮戊二酸类似物,抑制压力过载诱导的心肌病中适应不良的自噬。 | |||
T37618 |
Leukotriene B4 dimethyl amide
Leukotriene B4 dimethyl amide |
Others | Others |
LTB4 dimethyl amide is a moderate inhibitor of LTB4-induced degranulation of human neutrophils (Ki = 130 nM) and lysozyme release from rat PMNL. LTB4 dimethyl amide appears to be an antagonist of the LTB4 receptor on guinea pig lung membranes. | |||
T37993 |
16,16-dimethyl Prostaglandin F2α
16,16-dimethyl Prostaglandin F2α |
Others | Others |
16,16-dimethyl Prostaglandin F2α 可用于生命科学领域的相关研究。其产品编号为 T37993,CAS号为 39746-23-1。 | |||
T36041 |
16,16-dimethyl Prostaglandin A2
16,16-dimethyl Prostaglandin A2 |
Others | Others |
16,16-dimethyl PGA2 is a metabolism-resistant analog of PGA2 with a prolonged in vivo half-life. It inhibits the proliferation of Sendai virus in cultured African green monkey kidney cells by >90% at a concentration of 4 μg/ml. Daily infusion of 10 μg of 16,16-dimethyl PGA2 methyl ester into mice infected with influenza A virus increased survival by 40%. Similar treatment of mice inoculated with erythroleukemia cells delayed tumor growth and increased survival time. | |||
T36040 |
16,16-dimethyl Prostaglandin A1
16,16-dimethyl Prostaglandin A1 |
Others | Others |
16,16-dimethyl Prostaglandin A1 是一种前列腺素类似物,可以抑制 Lewis 肺癌和 B 16无黑色素瘤细胞中的 DNA 合成 (DNA synthesis),以及抑制 HSV 和 HIV-1的病毒复制。 | |||
T36213 |
16,16-dimethyl Prostaglandin D2
16,16-dimethyl Prostaglandin D2 |
Others | Others |
16,16-dimethyl PGD2 is a metabolically stable synthetic analog of PGD2. It enhances ADP-induced human platelet aggregation and increases systemic blood pressure in rats. | |||
T50008 |
2,2-Dimethyl-5-(2,5-xylyloxy)valeramide
5-(2,5-二甲基苯氧基)-2,2-二甲基戊酰胺,5-(2,5-dimethylphenoxy)-2,2-dimethylpentanamide |
Others | Others |
2,2-Dimethyl-5-(2,5-xylyloxy)valeramide (5-(2,5-dimethylphenoxy)-2,2-dimethylpentanamide) 是一种苯氧基家族化合物。它已被证明对神经系统具有刺激作用,包括神经元放电率的增加、突触传递的增加和神经递质释放的增加;还被证明对心血管系统有刺激作用,包括提高心率和血压。 | |||
T36214 |
16,16-dimethyl Prostaglandin E1
16,16-dimethyl Prostaglandin E1 |
Others | Others |
16,16-dimethyl Prostaglandin E1 是 PGE1 (T1626) 类似物,可诱导支气管收缩和血管平滑肌收缩,并抑制吲哚美辛诱导的细胞伸长。 | |||
T11046 |
Dimethyl-SGD-1882
Dimethyl-PBD dimer |
Others | Others |
Dimethyl-SGD-1882 (Dimethyl-PBD dimer) is a highly efficient DNA alkylating agent used as antibody-drug conjugate (ADC) cytotoxin. PBD Dimer is a DNA alkylating agent that inhibits DNA replication. | |||
T31323 |
Decane, 2,4-dimethyl-
2,4-dimethyl-decane |
Others | Others |
Decane, 2,4-dimethyl- is a biochemical. | |||
T10046 |
16,16-Dimethyl prostaglandin E2
16,16-dimethyl PGE2 |
Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
16,16-Dimethyl prostaglandin E2 is an orally active vertebrate Hematopoietic stem cells homeostasis critical regulator. It can act through EP2/EP4 and has an interaction with the Wnt pathway. | |||
T31332 |
Decane,2,3-dimethyl-
2,3-DIMETHYLDECANE,Decane, 2,3-dimethyl |
Others | Others |
Decane,2,3-dimethyl- 可作为化学合成中间体。其产品编号为 T31332,CAS号为 17312-44-6。 | |||
T77705 |
Diethyl 2,4-dimethylpyrrole-3,5-dicarboxylate
Diethyl 3,5-dimethyl-1H-pyrrole-2,4-dicarboxylate |
Others | Others |
Diethyl 2,4-dimethylpyrrole-3,5-dicarboxylate 是一种生化试剂,可用于研究生化反应。 | |||
T84576 |
16,16-dimethyl Prostaglandin F2β
9β,16,16-dimethyl PGF2α |
Others | Others |
16,16-Dimethyl PGF2β, a metabolically stable analog of PGF2β, mitigates bronchospasm in asthma patients, albeit with lower potency compared to PGE2. | |||
T36987 |
N,N-dimethyl Sphinganine (d18:0)
N,N-dimethyl Sphinganine (d18:0) |
Others | Others |
N,N-dimethyl Sphinganine (d18:0) is a sphingolipid that increases during development ofL. donovanipromastigotes.1 1.Silva, A.M., Cordeiro-da-Silva, A., and Coombs, G.H.Metabolic variation during development in culture of Leishmania donovani promastigotesPLoS Negl. Trop. Dis.5(12)e1451(2011) | |||
T84585 |
11-deoxy-16,16-dimethyl Prostaglandin E2
11-deoxy-16,16-dimethyl PGE2 |
Others | Others |
11-Deoxy-16,16-dimethyl Prostaglandin E2 (11-deoxy-16,16-dimethyl PGE2) is a stable synthetic analog of Prostaglandin E2 (PGE2), acting as an agonist for both EP2 and EP3 receptors. It effectively inhibits gastric acid secretion and ulcer formation in rats, with ED50 values of 1 mg/kg and 0.021 mg/kg, respectively. This compound is also 900 times more potent than Prostaglandin F2α (PGF2α) in inducing contraction of human respiratory tract smooth muscle in vitro. | |||
T0535 |
Memantine Related Compound B
美金刚杂质B,3,5-Dimethyl-1-adamantanol |
Others | Others |
Memantine Related Compound B (3,5-Dimethyl-1-adamantanol) 是Memantine 的杂质。 | |||
T50024 |
7-benzyl-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
|
HCV Protease | Microbiology/Virology; Proteases/Proteasome |
7-benzyl-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine 是丙型肝炎病毒 (HCV) 的抑制剂。 | |||
T37626 |
Latanoprost dimethyl amide
|
Others | Others |
Latanoprost dimethyl amide is a derivative of latanoprost and an isomer of latanoprost ethyl amide . N/A | |||
T37942 |
17-phenyl trinor Prostaglandin F2α dimethyl amide
17-phenyl trinor Prostaglandin F2α dimethyl amide |
Others | Others |
17-phenyl trinor Prostaglandin F2αdimethyl amide is an isomer of 17-phenyl trinor prostaglandin F2αethyl amide . N/A | |||
T28754 |
Sepin-1
Sepin 1,Sepin1,2H-Benzimidazole, 2,2-dimethyl-5-nitro-, 1,3-dioxide |
Others | Others |
Sepin-1 是一种分离酶的非竞争性抑制剂,IC50 为 14.8 µM。 Sepin-1可以通过抑制细胞增殖和诱导细胞凋亡来抑制小鼠和人类癌细胞系乳腺癌异种移植瘤的生长。 | |||
T31491 |
Dimethyl terephthalate
|
Others | Others |
Dimethyl terephthalate is a diester obtained from terephthalic acid and methanol. It is a white solid that melts to give a distillable colorless liquid. | |||
T36829 |
9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2
9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 |
Others | Others |
9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (Meteneprost) is a potent analog of prostaglandin E2 with an extended half-life in vivo. In combination with various other prostaglandin derivatives, it results in the termination of first trimester pregnancy in monkeys. A single intramuscular injection containing 0.5 mg of meteneprost and 7.5 mg of 17-phenyl trinor PGF1α is very effective in terminating early pregnancy. This prostaglandin mixture is ineffective on monkeys in their third trimes... | |||
T85251 |
1,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-PE
16:0 Dimethyl PE,1,2-N,NMe2DPPE,1,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-Phosphoethanolamine |
Others | Others |
1,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-PE is a derivative of 1,2-dipalmitoyl-sn-glycero-3-PE (1,2-DPPE) with two added methyl groups on its sn-3 moiety, which in aqueous suspensions, reduces the phase transition temperature relative to those of 1,2-DPPE and 1,2-dipalmitoyl-sn-glycero-3-N-methyl-PE (1,2-NMeDPPE). It is utilized in creating liposomes and monolayers for investigating membrane permeability and monolayer viscosity. | |||
T38463 |
Hexaethylene glycol dimethyl ether
|
Others | Others |
Hexaethylene glycol dimethyl ether, a PEG-based PROTAC linker, facilitates the synthesis of PROTACs. | |||
T37344 |
5,6-dimethyl-2-Thiouracil
|
Others | Others |
5,6-dimethyl-2-Thiouracil is a heterocyclic building block that has been used in the synthesis of anti-HIV-1 pyrimidinones.1 It has also been used as an internal standard for the quantification of thyreostats, including 2-thiouracil, in bovine plasma.2 |1. Navrotskii, M.B. Synthesis and anti-HIV-1 activity of new 2-[(2-phthalimidoethyl)thio]-4(3H)-pyrimidinone derivatives. Pharm. Chem. J. 39(9), 466-467 (2005).|2. Schmidt, K.S. In-house validation and factorial effect analysis of a liquid chroma... | |||
T11579 |
HSL-IN-3
HSL inhibitor 3,Ethyl 2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzoate |
Others | Others |
HSL-IN-3 (HSL inhibitor 3) 是激素敏感性脂肪酶的抑制剂,是一种硼酸衍生物。 | |||
T22739 |
DMPO
5,5-二甲基-1-吡咯啉-N-氧化物,5,5-Dimethyl-1-pyrroline N-oxide |
Others | Others |
DMPO (5,5-Dimethyl-1-pyrroline N-oxide) 是一种亲水自旋诱捕剂,具有细胞渗透性。DMPO 可用于超氧化物检测,可检测超氧阴离子和羟自由基。 | |||
T13720 |
Hexadimethrine bromide
1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide,海美溴铵,聚凝胺,Polybrene |
Others | Others |
Hexadimethrine bromide (Polybrene) 是一种阳离子聚合物,可以用于逆转录病毒和慢病毒感染,提高基因转移效率。 | |||
T35491 |
3,5-dimethyl PIT-1
|
Others | Others |
PtdIns-(3,4,5)-P3 (PIP3) serves as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains such as phosphatidylinositol 3-kinase (PI3K) or PTEN. Protein binding to PIP3 is important for cytoskeletal rearrangement and membrane trafficking and initiates an intricate signaling cascade that has been implicated in cancer. 3,5-dimethyl PIT-1 is a dimethyl analog of PIT-1, the selective inhibitor of PIP3/Akt PH domain binding, that is designed for more favorab... | |||
T29315 |
2,2'-Dimethyl hexestrol
|
Others | Others |
2,2'-Dimethyl hexestrol is a bioactive chemical. | |||
T20466 |
Keto-pantoyllactone
二氢-4,4-二甲基-2,3-呋喃二酮,Keto pantoyllactone,Ketopantoyllactone,Dihydro-4,4-dimethyl-2,3-furandione |
Others | Others |
Keto-pantoyllactone (Dihydro-4,4-dimethyl-2,3-furandione) 通过烟酰胺腺嘌呤二核苷酸磷酸的酮泛酰内酯依赖性氧化来测定。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8034 |
Dimethyl Trisulfide
|
Others; Endogenous Metabolite | Metabolism; Others |
Dimethyl trisulfide 是存在于大蒜,洋葱,西兰花和类似植物中的有机三硫化物。它是一种氰化物解毒剂。 | |||
T10886 |
Crocetine dimethyl ester
Dimethylcrocetin |
Antioxidant | oxidation-reduction |
Crocetine dimethyl ester (Dimethylcrocetin) 是一种藏红花素衍生物,具有抗氧化活性,抑制 AChE 活性,抑制细胞生长分化。 | |||
T5695 |
Dimethyl malonate
|
Others | Others |
Dimethyl malonate 是一种琥珀酸脱氢酶抑制剂。 | |||
TN6752 |
Dimethyl sulfone
|
Endogenous Metabolite | Metabolism |
Dimethyl sulfone 是内源性代谢产物的一种。 | |||
T0492 |
Dimethyl fumarate
富马酸二甲酯,DMF |
Reactive Oxygen Species; HIV Protease; Nrf2; Endogenous Metabolite; Autophagy | Autophagy; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome |
Dimethyl fumarate (DMF) 是具有口服活性且可透过血脑屏障的Nrf2激活剂,可诱导抗氧化剂基因表达上调。它是一种富马酸盐衍生物,可作抗炎和免疫调节剂,可研究多发性硬化症。 | |||
T8084 |
Dimethyl 4-hydroxyisophthalate
二甲基 4-羟基异邻苯二甲酸酯,Dimetghyl 4-Hydroxyisophthalate |
Others | Others |
Dimethyl 4-hydroxyisophthalate (Dimetghyl 4-Hydroxyisophthalate) 是水杨酸甲酯类似物。 | |||
T3746 |
Dimethyl phthalate
邻苯二甲酸二甲酯,Solvanom,Avolin,Fermine,避蚊酯 |
Others | Others |
Dimethyl phthalate (Fermine) 是一种邻苯二甲酸酯 (PAEs),是一种已知的内分泌干扰物,也是一种普遍存在的污染物。它常作为增塑剂,赋予硬质聚氯乙烯 (PVC) 树脂以柔韧性。 | |||
T2S0531 |
Pinoresinol dimethyl ether
(+)-Eudesmin,松脂素二甲醚 |
Others; PKC | Chromatin/Epigenetic; Cytoskeletal Signaling; Others |
Pinoresinol dimethyl ether 是一种非酚性呋喃木质素,从 Magnolia kobus 茎皮中分离得到,具有神经活性。它可刺激上游 MAPK、PKC 和 PKA 通路,诱导 PC12 细胞神经突起生长。 | |||
T8299 |
Dimethyl lithospermate B
丹酚酸B二甲酯,dmLSB |
Sodium Channel | Membrane transporter/Ion channel |
Dimethyl lithospermate B (dmLSB) 是 Na+通道的选择性激动剂,减缓钠电流 (INa) 失活,导致动作电位 (AP) 早期内向电流增加。 | |||
T66911 |
1,3-Dimethoxybenzene
Resorcinol dimethyl ether |
Others | Others |
1,3-Dimethoxybenzene (Resorcinol dimethyl ether) 是一种来自德国榛子中的二甲氧基苯类化合物,是合成其他化合物的中间体。 | |||
TN2898 |
Kaempferol-7,4'-dimethyl ether
3,5-Dihydroxy-4',7-dimethoxyflavone |
Antioxidant; Antifection | Microbiology/Virology; oxidation-reduction |
Kaempferol-7,4'-dimethyl ether 是从 Zingiber phillipseae 的根茎中分离得到的,对金黄色葡萄球菌和大肠杆菌具有抗氧化活性,MIC 分别为 200 和 225 μg/ml。 | |||
TN7231 |
Di-O-methylhonokiol
Honokiol dimethyl ether |
Antioxidant | oxidation-reduction |
Di-O-methylhonokiol (Honokiol dimethyl ether) 是Magnolia grandiflora L 的酚类成分,具有抗微生物活性,对革兰氏阳性和抗酸细菌和真菌具有显著的抗氧化活性。 | |||
T4824 |
5,6-Dimethyl-1H-benzo[d]imidazole
5,6-Dimethylbenzimidazole,5,6-二甲基苯并咪唑 |
Others; Endogenous Metabolite | Metabolism; Others |
5,6-Dimethyl-1H-benzo[d]imidazole (5,6-Dimethylbenzimidazole) 是内源性代谢产物的一种。 | |||
T40807 |
1,3-Dimethylpyrazole
1,3-Dimethyl-1H-pyrazole,2,5-Dimethylpyrazole |
Others | Others |
1,3-Dimethylpyrazole (2,5-Dimethylpyrazole) 是一种存在于毛竹根的生物活性物质。 | |||
T21157 |
Sebacic acid dimethyl ester
Sebacic acid, dimethyl ester (8CI),Dimethyl sebacate,Decanedioic acid, 1,10-dimethyl ester,Decanedioic acid, dimethyl ester |
||
Dimethyl sebacate was used in the biosynthesis of oligomeric sebacates, lubricant oils. Dimethyl sebacate was a convenient starting material for cyclization of N-Succinylglycine dimethyl ester. Dimethyl sebacate was also used to prepare polytetramethylene | |||
TN1552 |
7,8-Dimethoxycoumarin
7,8-dimethoxychromen-2-one,Daphnetin dimethyl ether |
Others | Others |
7,8-Dimethoxycoumarin 是一种从 Artemisia caruifolia 和 Wikstroemia indica 中分离出来的天然产物。 | |||
T19278 |
Dicaprylyl carbonate
碳酸二辛酯,Dimethyl carbonate |
Others | Others |
Dicaprylyl carbonate (Dimethyl carbonate) 是植物来源的固体脂肪,是干燥润肤剂。它具有强大的皮肤相容性和全面的性能,如防晒滤光片的增溶和分散能力。 | |||
TN6822 |
3,5-Dimethoxytoluene
Orcinol dimethyl ether,1,3-dimethoxy-5-methylbenzene |
Others | Others |
3,5-Dimethoxytoluene (Orcinol dimethyl ether) 是玫瑰中主要香味成分,具有镇静作用,可作为一种害虫引诱剂使用。 | |||
T8013 |
(S)-(-)-Citronellal
(S)-(-)-3,7-Dimethyl-6-Octenal,(-)-香茅醛,(-)-Citronellal |
Others; Endogenous Metabolite | Metabolism; Others |
(S)-(-)-Citronellal ((S)-(-)-3,7-Dimethyl-6-Octenal) 是存在于Corymbia citriodora 和Cymbopogon nardus 中的一种单萜类化合物。 | |||
TN6793 |
Demethylisoencecalin
6-Acetyl-5-hydroxy-2,2-dimethyl-2H-1-benzopyran |
Others | Others |
Demethylisoencecalin (6-Acetyl-5-hydroxy-2,2-dimethyl-2H-1-benzopyran) 具有抗高血糖活性。 | |||
TN7136 |
1,7-dimethyl-1H-indole-3-carbaldehyde
1,7-dimethylindole-3-carbaldehyde,ZINC14592128,N,7-Dimethylindole-3-carbaldehyde |
Others | Others |
1,7-dimethyl-1H-indole-3-carbaldehyde (ZINC14592128) 是一种海洋来源的天然产物,存在于 Lyngbya majuscula。 | |||
T4S2354 |
Dimethylfraxetin
二甲基白蜡树亭,Fraxetin dimethyl ether,6,7,8-Trimethoxycoumarin |
Carbonic Anhydrase | Metabolism |
Dimethylfraxetin (6,7,8-Trimethoxycoumarin) 是Carbonic anhydrase 抑制剂(Ki:0.0097 μM)。 | |||
T7438 |
3,5-Dimethoxyphenol
Phloroglucinol dimethyl ether,3,5-二甲氧基苯酚 |
Tyrosinase | Proteases/Proteasome |
3,5-Dimethoxyphenol (Phloroglucinol dimethyl ether) 是一种存在于人类食用红豆杉的叶子中的毒素代谢物。 | |||
TN7058 |
Dihydrolapachenole
6-methoxy-2,2-dimethyl-3,4-dihydro-2H-benzo[h]chromene |
Others | Others |
Dihydrolapachenole (6-methoxy-2,2-dimethyl-3,4-dihydro-2H-benzo[h]chromene) 可分离自T. chrysantha。 | |||
TN7251 |
Olivetol Dimethyl Ether
1,3-dimethoxy-5-pentylbenzene |
Others | Others |
Olivetol Dimethyl Ether 是一种单酰基甘油,具有镇痛活性和潜在的抗炎活性,可以抑制脂肪酸的合成。 | |||
T5547 |
Furaneol
呋喃酮,4-Hydroxy-2,5-dimethyl-3(2H)furanone,HDMF |
Antibacterial | Microbiology/Virology |
Furaneol (HDMF) 主要来源于美洲葡萄(Vitis labrusca)及其杂交品种。作为水果中的重要香气成分,在一些葡萄酒中展现出类似草莓的香气特征。 | |||
TN7115 |
3,5-Dimethoxystilbene
3,5-二甲氧基二苯乙烯,cis-Pinosylvin dimethyl ether |
Others | Others |
3,5-Dimethoxystilbene (cis-Pinosylvin dimethyl ether) 是一种从短叶松 Pinus bunksiuna 树皮中分离出来的天然产物。 | |||
T2729 |
Scoparone
滨蒿内酯,Escoparone,Scoparon,Aesculetin dimethyl ether,6,7-dimethoxycoumarin,6,7-Dimethylesculetin |
Others | Others |
Scoparone (Aesculetin dimethyl ether) 是分离自毛蒿中,具有抗凝血,抗血管舒张作用和抗炎活性。 | |||
T3329 |
4',7-Dimethoxyisoflavone
4',7-二甲氧基异黄酮,Dimethoxydaidzein,Daidzein dimethyl ether |
Endogenous Metabolite; Antifungal | Metabolism; Microbiology/Virology |
4',7-Dimethoxyisoflavone (Daidzein dimethyl ether) 是从阔荚合欢中分离的黄酮类化合物,有抗真菌作用,可抑制大鼠前列腺睾酮5α-还原酶。 | |||
T0983 |
Penicillamine
青霉胺,d-penicillamin,Dimethyl Cysteine,D-青霉胺,Artamine,D-(-)-Penicillamine |
Antibiotic | Microbiology/Virology |
Penicillamine (Artamine) 是一种 penicillin 的代谢降解产物,是一种螯合剂,可作用于威尔逊氏病。 | |||
TN2740 |
2,6-Dimethyl-3-O-methyl-
2,6-Dimethyl-3-O-methyl-4-(2-methylbutyryl)phloroglucinol |
Others | Others |
2,6-Dimethyl-3-O-methyl- 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2740,CAS号为 97761-91-6。 | |||
TN6921 | Dimethyl Azelate | ||
Dimethyl Azelate is a natural product. | |||
T16442 |
PCO371
2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl- |
Thyroid hormone receptor(THR) | Endocrinology/Hormones |
PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) 是口服具有活性的甲状旁腺激素受体 1 的完全激动剂,对 PTHR2 无作用 | |||
TN5695 |
1,6-Dimethyl-5-vinyl-9,10-dihydrophenanthren-2-ol
2-Hydroxy-1,6-dimethyl-5-vinyl-9,10-dihydrophenathrene |
||
1,6-Dimethyl-5-vinyl-9,10-dihydrophenanthren-2-ol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5695,CAS号为 745056-83-1。 | |||
T7344 |
SDMA
NG,NG'-Dimethyl-L-arginine,Symmetric dimethylarginine,对称N,N-二甲基精氨酸 |
Endogenous Metabolite | Metabolism |
SDMA (Symmetric dimethylarginine) 是一氧化氮 (NO) 合酶的内源性抑制剂。 | |||
TN4981 |
Secologanin dimethyl acetal
金银花 |
Others | Others |
Secologanin dimethyl acetal induces significant neurite outgrowth. | |||
T2883 |
Syringic acid
3,5-dimethyl ether Gallic Acid,SYRA,3,5-dimethoxy-4-hydroxy Benzoic Acid,丁香酸,NSC 2129 |
Others; Endogenous Metabolite; Antibacterial | Metabolism; Microbiology/Virology; Others |
Syringic acid (3,5-dimethoxy-4-hydroxy Benzoic Acid) 能抑制低密度脂蛋白的氧化。 | |||
TN3100 |
5-Acetoxymatairesinol dimethyl ether
|
Others | Others |
5-Acetoxymatairesinol dimethyl ether 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3100,CAS号为 74892-45-8。 | |||
TN4413 |
Lariciresinol dimethyl ether
|
Others | Others |
Lariciresinol dimethyl ether is a natural product from Rostellularia procumbens. | |||
TN6237 |
Forsythide dimethyl ester
|
||
Forsythide dimethyl ester 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6237,CAS号为 42830-22-8。 | |||
T5769 |
Stachydrine
Methyl hygrate betaine,水苏碱,L-stachydrine,Proline betaine,N,N-Dimethyl-L-proline |
NF-κB; Endogenous Metabolite | Metabolism; NF-κB |
Stachydrine (N,N-Dimethyl-L-proline) 是中国草本植物益母草的主要成分,具有促进血液循环和消除血瘀的功效。Stachydrine (N,N-Dimethyl-L-proline) 能够抑制NF-κB 信号通路。 | |||
TN1587 |
Dihydroseselin
ZINC302323,8,8-dimethyl-9,10-dihydropyrano[2,3-h]chromen-2-one,二氢邪蒿内酯 |
Others | Others |
Dihydroseselin (8,8-dimethyl-9,10-dihydropyrano[2,3-h]chromen-2-one) 是一种源自 Toddalia 根的香豆素。 | |||
T21290 |
1,3-Dioxane, 2,4-dimethyl-
|
||
1,3-Dioxane, 2,4-dimethyl- is a bioactive chemical. | |||
T3759 |
3,4-Dimethoxycinnamic acid
Dimethylcaffeic acid,3,4-二甲氧基肉桂酸,Caffeic acid dimethyl ether,O-Methylferulic acid |
Apoptosis; Virus Protease; Reactive Oxygen Species | Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB |
3,4-Dimethoxycinnamic acid (O-Methylferulic acid) 是从 Securidaca inappendiculata Hassk 中提取和纯化的单体。 3,4-Dimethoxycinnamic acid 通过 ROS 介导的信号通路对 L-02 细胞发挥抗凋亡作用。抗凋亡作用。 | |||
TN5564 |
10-Hydroxyoleoside dimethyl ester
|
||
10-Hydroxyoleoside dimethyl ester 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5564,CAS号为 91679-27-5。 | |||
TN4875 |
Quercetin 3,3'-dimethyl ether
|
Others | Others |
Quercetin 3,3'-dimethyl ether may have moderate estrogenic activity. | |||
TN3986 |
Eriodictyol 7,3'-dimethyl ether
|
Antioxidant; Antibacterial | Microbiology/Virology; oxidation-reduction |
Eriodictyol 7,3'-dimethyl ether 是首次从 B. riparia 提取的黄酮类化合物,具有抗氧化和抗菌活性。 | |||
TN4877 | Quercetin 3,4'-dimethyl ether | ERK; BCL; MAPK; Caspase; JNK | Apoptosis; MAPK; Proteases/Proteasome |
Quercetin 3,4'-dimethyl ether shows anti-lipid peroxidation activity (IC 50 values of 0.3 uM), it also shows anti-inflammatory activity. Quercetin 3,4'-dimethyl ether could be useful in the development of novel anticancer agents, it has high cytotoxic aga | |||
TN2695 |
2,3-Dihydroamentoflavone 7,4'-dimethyl ether
|
Others | Others |
2,3-Dihydroamentoflavone 7,4'-dimethyl ether exhibits cytotoxicities (ED50 values < 4 microg/mL) against P-388 and/or HT-29 cell lines in vitro. | |||
TN1839 |
Kumatakenin
Jaranol,华良姜素,熊竹素,Kaempferol 3,7-O-dimethyl ether |
Apoptosis; Anti-infection | Apoptosis; Microbiology/Virology |
Kumatakenin 是一种从丁香中分离得到的黄酮类天然产物,可诱导卵巢癌细胞凋亡。 | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01622 |
KDM3B Protein, Human, Recombinant (His & Myc & SUMO)
[histone H3]-dimethyl-L-lysine(9) demethylase 3B,Ly... |
Human | E. coli |
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. | |||
TMPH-01529 |
INMT Protein, Human, Recombinant (His & SUMO)
Thioether S-methyltransferase,INMT,Aromatic alkylamine N-met... |
Human | E. coli |
Functions as thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide. Plays an important role in the detoxification of selenium compounds. Catalyzes the N-methylation of tryptamine and structurally related compounds. | |||
TMPH-03017 |
CYP51 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)
Cytochrome P450-14DM,Sterol 14alpha-demethylase,Sterol 14-al... |
Mycobacterium tuberculosis | Baculovirus Insect Cells |
Its precise biological substrate is not known. Catalyzes C14-demethylation of lanosterol, 24,25-dihydrolanosterol and obtusifoliol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. | |||
TMPH-03447 |
ERG11 Protein, S. cerevisiae, Recombinant (GST)
Ergosterol biosynthetic protein 11,Cytochrome P450 51,ERG11,... |
Saccharomyces cerevisiae | E. coli |
Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. ERG11 Protein, S. cerevisiae, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 29.1 kDa and the accession number is P10614. | |||
TMPH-01733 |
DDAH2 Protein, Human, Recombinant (GST & His)
Inactive dimethylarginine dimethylaminohyd... |
Human | E. coli |
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. DDAH2 Protein, Human, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 61.2 kDa and the accession number is O95865. | |||
TMPH-01732 |
DDAH1 Protein, Human, Recombinant (His & Myc)
DDAHI,N(G),N(G)-dimethylarginine dimethyla... |
Human | E. coli |
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. DDAH1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 38.4 kDa and the accession number is O94760. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9242 |
Dimethyl-d6 Sulfoxide
|
Others | Others |
Dimethyl-d6 Sulfoxide 是二甲基亚砜 (DMSO, (CH3) 2S = O) 的氢 (“H”) 被另一种同位素氘 (“d”) 取代的形式。二甲基-d6 亚砜是核磁共振光谱中的常用溶剂。 | |||
T11045 |
Dimethyl fumarate-d6
Dimethyl fumarate D6,DMF D6 |
Others | Others |
Dimethyl fumarate D6 is a deuterium labeled Dimethyl fumarate. can induces upregulation of antioxidant gene expression. | |||
TMIH-0193 |
Dimethyl Sildenafil-d5
|
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Dimethyl Sildenafil-d5 是 Dimethyl Sildenafil 的氘代化合物。 | |||
TMIJ-0457 |
Daminozide-d6 (dimethyl-d6)
|
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Daminozide-d6 (dimethyl-d6) 是 Daminozide 的氘代化合物。Daminozide 的 CAS 号为 1596-84-5。Daminozide 是一种植物生长调节剂,选择性地抑制 KDM2/7 JmjC 亚家族,对PHF8、KDM2A和KIAA1718的IC50值分别为 0.55、1.5 和 2.1 μM。 | |||
TMIH-0191 |
dimethyl 2-(methyl-d3)malonate
|
||
dimethyl 2-(methyl-d3)malonate 是 dimethyl 2-(methyl)malonate 的氘代化合物。dimethyl 2-(methyl)malonate 的 CAS 号为 516-05-2。Methylmalonic acid 是癌症患者缺乏维生素 B-12的指标。 | |||
TMIJ-0459 |
Methamidophos-d6 (dimethyl-d6)
|
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Methamidophos-d6 (dimethyl-d6) 是 Methamidophos 的氘代化合物。 | |||
TMIJ-0361 |
Dimethyl Fumarate-2,3-d2
|
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Dimethyl Fumarate-2,3-d2 是 Dimethyl Fumarate 的氘代化合物。Dimethyl Fumarate 的 CAS 号为 624-49-7。Dimethyl fumarate 是具有口服活性且可透过血脑屏障的Nrf2激活剂,可诱导抗氧化剂基因表达上调。它是一种富马酸盐衍生物,可作抗炎和免疫调节剂,可研究多发性硬化症。 | |||
TMIJ-0296 |
Bezafibrate-d6 (dimethyl-d6)
|
||
Bezafibrate-d6 (dimethyl-d6) 是 Bezafibrate 的氘代化合物。Bezafibrate 的 CAS 号为 41859-67-0。Bezafibrate 是一种降血脂剂,是PPAR的激动剂,对人以及鼠PPARα、PPARγ和PPARδ的EC50分别为 50、60和20 μM, 以及 90、55 和110 μM。 | |||
TMIJ-0462 |
trans-Permethrin-d6 (dimethyl-d6)
|
||
trans-Permethrin-d6 (dimethyl-d6) 是 trans-Permethrin 的氘代化合物。trans-Permethrin 的 CAS 号为 551877-74-8。 | |||
TMIJ-0464 |
trans-Cypermethrin-d6 (dimethyl-d6)
|
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trans-Cypermethrin-d6 (dimethyl-d6) 是 trans-Cypermethrin 的氘代化合物。trans-Cypermethrin 的 CAS 号为 67375-30-8。alpha-Cypermethrin 是一种合成拟除虫菊酯杀虫剂,用于大规模商业农业应用。 | |||
TMIJ-0481 |
Fenitrothion-d6 (O,O-dimethyl-d6)
|
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Fenitrothion-d6 (O,O-dimethyl-d6) 是 Fenitrothion 的氘代化合物。Fenitrothion 的 CAS 号为 122-14-5。 | |||
TMIJ-0467 |
Dimethoate-d6 (O,O dimethyl-d6)
|
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Dimethoate-d6 (O,O dimethyl-d6) 是 Dimethoate 的氘代化合物。Dimethoate 的 CAS 号为 60-51-5。Dimethoate 是一种系统性和接触性杀虫剂,用于控制牛蛴螬和农场动物的某些其他害虫。 | |||
TMIJ-0476 |
Chlorotoluron-d6 (N,N-dimethyl-d6)
|
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Chlorotoluron-d6 (N,N-dimethyl-d6) 是 Chlorotoluron 的氘代化合物。Chlorotoluron 的 CAS 号为 15545-48-9。Chlorotoluron 是取代的苯基脲除草剂,普遍用于谷物作物的选择性杂草控制,是环境污染物。 | |||
TMID-0265 |
Dothiepin-d6 HCl (N,N-dimethyl-d6) (cis/trans mixture)
|
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Dothiepin-d6 HCl (N,N-dimethyl-d6) (cis/trans mixture) 是 Dothiepin HCl 的氘代化合物。Dothiepin HCl 的 CAS 号为 25627-36-5。 | |||
TMID-0020 |
N-Nitrosodimethylamine-d6
|
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N-Nitrosodimethylamine-d6 是 N-Nitrosodimethylamine 的氘代化合物。N-Nitrosodimethylamine 的 CAS 号为 62-75-9。 | |||
TMIH-0023 |
1-[3-carboxypropyl]-3,7-dimethylxanthine-d6
pentoxyfylline metabolite 1-d6 |
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1-[3-carboxypropyl]-3,7-dimethylxanthine-d6 是 1-[3-carboxypropyl]-3,7-dimethylxanthine 的氘代化合物。 | |||
TMIH-0361 |
N,N'-Dimethylarginine-d6
|
||
N,N'-Dimethylarginine-d6 是 N,N'-Dimethylarginine 的氘代化合物。N,N'-Dimethylarginine 的 CAS 号为 30344-00-4。SDMA 是一氧化氮 (NO) 合酶的内源性抑制剂。 | |||
TMIH-0021 |
1-(5-hydroxyhexyl)-3,7-dimethylxanthine-d6
pentoxyfylline metabolite 2-d6 |
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1-(5-hydroxyhexyl)-3,7-dimethylxanthine-d6 是 1-(5-hydroxyhexyl)-3,7-dimethylxanthine 的氘代化合物。 | |||
TMIJ-0045 |
3,3-Dimethylbutanoic acid-d9
|
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3,3-Dimethylbutanoic acid-d9 是 3,3-Dimethylbutanoic acid 的氘代化合物。3,3-Dimethylbutanoic acid 的 CAS 号为 1070-83-3。 | |||
TMIJ-0418 |
2,4-Dimethylphenol-d3 (3,5,6-d3)
|
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2,4-Dimethylphenol-d3 (3,5,6-d3) 是 2,4-Dimethylphenol 的氘代化合物。2,4-Dimethylphenol 的 CAS 号为 105-67-9。 | |||
TMIJ-0478 |
Pirimicarb-d6 (dimethylcarbamate-d6)
|
||
Pirimicarb-d6 (dimethylcarbamate-d6) 是 Pirimicarb 的氘代化合物。Pirimicarb 的 CAS 号为 23103-98-2。 | |||
TMIJ-0390 |
N,N-Dimethylformamide-d7
|
||
N,N-Dimethylformamide-d7 是 N,N-Dimethylformamide 的氘代化合物。N,N-Dimethylformamide 的 CAS 号为 68-12-2。 | |||
T70990 |
ADMA-d6
|
||
NG,NG-dimethyl-L-arginine-d6 (ADMA-d6) (hydrochloride) is intended for use as an internal standard for the quantification of NG,NG-dimethyl-L-arginine by GC- or LC-MS. ADMA is an endogenous inhibitor of nitric oxide synthase (NOS). It is formed from arginine by protein arginine methyltransferases (PRMTs) and degraded by dimethylarginine dimethylaminohydrolases (DDAHs) and alanine-glyoxylate aminotransferase 2 (AGXT2). ADMA levels are increased concomitant with an increase in blood pressure in Da... |