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Cat. No. Product Name
L4520 抗菌活性库

904 compounds
904 种具有抗菌活性的化合物,是抗菌药物研发的有力工具;
L3900 DNA 损伤和修复分子库

910 compounds
910 个与 DNA 损伤和修复紧密相关的化合物集合,是高通量筛选,高内涵筛选的良好载体;
L3980 DNA损伤/修复库Plus

667 compounds
667 种 DNA 损伤/修复靶向、结构新颖的化合物;

化合物库

抗菌活性库
Cat.No: L4520
Compounds: 904
DNA 损伤和修复分子库
Cat.No: L3900
Compounds: 910
DNA损伤/修复库Plus
Cat.No: L3980
Compounds: 667
Cat. No. Product Name Target Signaling Pathways
T9318 TP0586532

Others Others
TP0586532 是有效的non-hydroxamate LpxC 抑制剂 (IC50=0.101 μM)。TP0586532具有低心血管风险的特点,对肺炎克雷伯菌有效,包括耐药菌株。
T38236 2′-Deoxy-2′-fluoroguanosine

Nucleoside Antimetabolite/Analog; Influenza Virus Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
2′-Deoxy-2′-fluoroguanosine 是一种核苷类似物,有效抑制流感病毒,抑制A 型和B 型流感病毒的EC90值 <0.35 μM。2′-Deoxy-2′-fluoroguanosine 显著抑制流感病毒在上呼吸道中的复制,从而改善鼻腔炎症和发烧。
T22287 Cefteram pivoxil

头孢特仑新戊酯,Ro 19-5248,T-2588

Antibacterial; Antibiotic Microbiology/Virology
Cefteram pivoxil (T-2588) 是一种口服头孢菌素抗生素,可治疗细菌感染。
T9858 5-(3-bromo-4,5-dihydroisoxazol-5-yl)-3-(4-(tert-butyl)phenyl)-1,2,4-oxadiazole

Parasite Microbiology/Virology
Antileishmanial agent-2 是一种基于 3-Br-isoxazoline 的疟原虫抑制剂恶性疟原虫(D10 和 W2 菌株)和利什曼原虫属。 (L. infantum 和 L.tropica) 前鞭毛体,IC50 为 0.035、0.058、3.5 和 7.5 μM。
T5325 Nifurtimox

硝呋替莫,BAY-2502,BAY-A-2502

Dehydrogenase; Parasite Metabolism; Microbiology/Virology
Nifurtimox (BAY-A-2502) 是一种用于锥虫病的抗虫剂,可影响乳酸脱氢酶活性。它有潜力研究神经母细胞瘤细胞。
T10903 CWHM-1552

Parasite Microbiology/Virology
CWHM-1552 是一种有效的恶性疟原虫抑制剂。 对于 3D7 和 Dd2 菌株,IC50 分别为 51 nM 和 53 nM。
T29187 YM-53403

Others Others
YM-53403是具有抗病毒活性,可有效抑制属于A 亚群和B 亚组的RSV 毒株的复制,可用来治疗呼吸道合胞病毒感染。
T10378 Artelinic acid

Parasite Microbiology/Virology
Artelinic acid 是水溶性青蒿素类似物,具有抗疟活性,用于治疗恶性疟原虫多重耐药菌株。
T9580 SB-734117

HCV Protease Microbiology/Virology; Proteases/Proteasome
SB-734117 抑制几种 HCMV 菌株的生产性复制。 SB-734117 表现出多种药理作用,是 AGC 和 CMCG 激酶组中几种蛋白质的抑制剂。
T7804 Garenoxacin mesylate hydrate

Garenoxacin mesylate [USAN],加雷沙星甲磺酸盐,BMS284756 (Mesylate hydrate)

Antibacterial Microbiology/Virology
Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) 是一种新型口服 des-fluoro(6) 喹诺酮,具有强抗菌活性,抗呼吸道病原体。
T10356 AQ-13 dihydrochloride

Parasite Microbiology/Virology
AQ-13 dihydrochloride 是一种氨基喹啉类抗疟药,对耐药型菌株 Plasmodium falciparum 有抑制作用。
T10329 anti-TB agent 1

Antibiotic Microbiology/Virology
anti-TB agent 1是一种有效的口服活性抗结核化合物,对结核分枝杆菌H37Rv、rRMP 和rINH 的MICs<2nM。
T7342 BM212

Antibacterial Microbiology/Virology
BM212 是一种分枝杆菌膜蛋白 MmpL3抑制剂。它抑制结核分枝杆菌和部分非结核分枝杆菌,抗结核杆菌 H37Rv 菌株的 MIC 值为 5 µM。
T4063 Delafloxacin

ABT492,WQ-3034,德拉沙星,RX-3341

Antibacterial; Antibiotic Microbiology/Virology
Delafloxacin (WQ-3034) 是一种广谱氟喹诺酮类抗生素,抑制耐药性的金黄色葡萄球菌,肺炎链球菌和肺炎克雷伯菌。
T14324 Artemisone

BAY 44-9585,Artemifone,青蒿酮

Others; Parasite Microbiology/Virology; Others
Artemisone (BAY 44-9585) 是一种半合成的有效抗疟疾剂,还是一种人CMV 的有效抑制剂,可抑制多种P. falciparum,平均IC50值为 0.83 nM。
T19825 X-alpha-Gal

Others Others
X-alpha-Gal 是 α-半乳糖苷酶的底物。它用于区分酵母的α-半乳糖苷酶阳性菌株。
T1610 Metaxalone

Skelaxin,Methaxalonum,美他沙酮,Zorane,NSC170959,AHR438

Others Others
Metaxalone (Methaxalonum) 具有肌肉松弛作用。
T7897 PK150

Others; Antibacterial Microbiology/Virology; Others
PK150 是一种 Sorafenib 类似物,具有抗菌活性。它抑制甲氧西林敏感金黄色葡萄球菌,耐甲氧西林金黄色葡萄球菌,万古霉素中介金黄色葡萄球菌的 MIC 分别为 0.3,0.3-1,0.3 µM。
T8620 piperacillin

Pipril,Pipracil,哌拉西林,Pipercillin

Antibacterial Microbiology/Virology
Piperacillin (Pipercillin) 是半合成青霉素,可以作用于革兰氏阳性和革兰氏阴性需氧和厌氧菌。与其他青霉素相比,它对产生 β-内酰胺酶的菌类表现出更强的活性。
T8701 GRP-60367

Others Others
GRP-60367 是一种小分子狂犬病病毒进入抑制剂,对某些 RABV 株具有纳摩尔作用效果。
T72037 Anti-Influenza agent 4

Influenza Virus Microbiology/Virology
Anti-Influenza agent 4 是一种有效且具有选择性的流感病毒 抑制剂,对A/Parma 和 A/Roma 毒株具有抑制作用, EC50 分别为 62 nM 和150 nM。
T28946 Tenofovir exalidex

Tenofovir,HDP-Tenofovir,CMX-157,CMX157,CMX 157

Antiviral Immunology/Inflammation
Tenofovir exalidex (CMX 157) 是一种非环核苷酸类似物 Tenofovir 的脂质结合物,对野生型和抗逆转录病毒耐药的 HIV 毒株,包括多药核苷/核苷酸类似物耐药病毒,都有活性。Tenofovir exalidex 对人外周血单个核细胞中所有主要的HIV-1和HIV-2亚型以及单核细胞来源的巨噬细胞中所有 HIV-1 菌株具有活性,EC50 范围在 0.2 和 7.2 nM 之间。Tenofovir exalidex 具有口服活性,无明显毒性。Tenofovir exalidex 对 HBV 也有活性。
T6549 Isepamicin sulfate

Isepamicine (Isepamycin,硫酸异帕米星,Isepamicin Sulphate,Isepacin,sch21420) Sulphate

Antibacterial; Antibiotic Microbiology/Virology
Isepamicin sulfate (sch21420) Sulphate) 是一种广谱氨基糖苷类抗生素,对产生 I 型 6-乙酰转移酶的菌株具有良好的活性,通过靶向细菌 30S 核糖体亚基来抑制细菌蛋白质合成。
T22438 Tetramethylthiuram monosulfide

一硫化四甲基秋兰姆,TMTM

Others Others
Tetramethylthiuram monosulfide 被广泛用作橡胶加工技术中的催化剂,它具有中等毒性,并在菌株 TA 100 和 TA 1535(鼠伤寒沙门氏菌 LT 2)中引起点突变。
T14489 Azvudine

4-氨基-1-(4-C-叠氮基-2-脱氧-2-氟-BETA-D-呋喃阿拉伯糖基)-2(1H)-嘧啶酮,FNC,RO-0622

HCV Protease; HBV; HIV Protease; Reverse Transcriptase Microbiology/Virology; Proteases/Proteasome
Azvudine (FNC) 是一种有效的核苷逆转录酶抑制剂 (NRTI),对 HIV、HBV 和 HCV 具有抗病毒活性。它抑制耐 NRTI 的病毒株,高效抑制 HIV-1和 HIV-2。
T0170 Phosphonic acid, [(2R,​3S)​-​3-​methyloxiranyl]​-​, calcium salt (9CI)

phosphonomycin calcium,Fosfomycin calcium,磷霉素钙,phosphomycin calcium

Antibiotic Microbiology/Virology
Phosphonic acid, [(2R,​3S)​-​3-​methyloxiranyl]​-​, calcium salt (9CI) (phosphonomycin calcium)是一种抗生素,用于治疗敏感菌株引起的尿路感染和肠道感染。
T3114 Povidone iodine

Betadine,聚乙烯吡酮磺,Povidone-iodine,聚乙烯吡咯烷酮碘,Isodine,PVP iodine,iodopovidone,PVP-I

Antibacterial; Antibiotic Microbiology/Virology
Povidone iodine (Povidone-iodine) 有很强的抗细菌活性, 可杀死 MRSA 和 MSSA 菌株,其 MICs 值分别为 31.25 mg/L 和7.82 mg/L。
T12154L N-Desethyl amodiaquine dihydrochloride

Parasite Microbiology/Virology
N-Desethyl amodiaquine dihydrochloride 是一种抗寄生虫剂,是主要的生物活性阿莫地喹代谢物。它对菌株 V1/S 和 3D7 的 IC50值分别为 97 nM 和 25 nM。
T0331L Moxifloxacin

Avelox,Moxeza,莫西沙星

Others; Antibacterial; Antibiotic Microbiology/Virology; Others
Moxifloxacin (Avelox) 是一种8-甲氧基喹诺酮类口服有效抗菌药物,用于急性细菌性鼻窦炎,慢性支气管炎的急性细菌性加重和感染性肺炎的研究。
TP1364L ALX 40-4C acetate

ALX 40-4C acetate(143413-49-4 free base)

Apelin receptor; CXCR Autophagy; GPCR/G Protein; Immunology/Inflammation
ALX 40-4C acetate 是趋化因子受体 (Ki = 1 μM) 的 CXCR4 抑制剂,可抑制 HIV-1 X4 株的复制。 ALX 40-4C acetate 是 APJ 受体的拮抗剂 (IC50 = 2.9 μM)。
T17210L Vaborbactam ammonium salt

RPX7009 ammonium salt,Vaborbactam ammonium salt(1360457-46-0 Free base)

Antibacterial Microbiology/Virology
Vaborbactam ammonium salt 是一种 β-内酰胺酶抑制剂,可以恢复碳青霉烯类药物对 KPC 生产菌株的活性,常与其它药物连用来研究真菌感染。
T1312 Nafcillin sodium monohydrate

CL 8491,萘夫西林钠,nafcillin sodium

Antibacterial; Antibiotic Microbiology/Virology
Nafcillin sodium monohydrate (CL 8491) 是一种抗生素,是可逆的β-lactamase 抑制剂。它用于治疗由耐青霉素的葡萄球菌菌株引起的感染。
T11815 Lanopepden

GSK 1322322,GSK-1322322B,GSK-1322322J

Antibiotic Microbiology/Virology
Lanopepden (GSK 1322322) 是一种有效的肽去甲酰酶抑制剂,抑制金黄色葡萄球菌,抑制 ATCC 29213 和 ATCC 25923 菌株,可用于研究肺炎、皮肤病和传染病。
T36692 Fanotaprim

DHFR Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
Fanotaprim 是二氢叶酸还原酶的有效抑制剂,抑制 tgDHFR (Toxoplasma gondiiDHFR) 和 hDHFR (human DHFR)的 IC50分别为 1.57 和 308 nM。Fanotaprim 在研究弓形虫病方面具有价值。
T9449 Nitrofural

[(E)-(5-nitrofuran-2-yl)methylideneamino,(E)-2-((5-硝基呋喃-2-基)亚甲基)肼甲酰胺

Antibacterial Microbiology/Virology
Nitrofural 是 20 世纪已在临床应用中确立的硝基呋喃。 Nitrofural 在临床上对广泛的革兰氏阳性和革兰氏阴性细菌(包括许多常见的泌尿道病原体菌株)仍然有效。
T2162 Maribavir

BW1263W94,GW257406X,Benzimidavir,马立巴韦,1263W94

Others; HCV Protease Microbiology/Virology; Others; Proteases/Proteasome
Maribavir (GW257406X) 是一种可口服的苯并咪唑核苷化合物,具有抗巨细胞病毒的活性。
T79088 Chlamydia pneumoniae-IN-1

Antibacterial Microbiology/Virology
Chlamydia pneumoniae-IN-1 是一种对衣原体有抑制作用的苯并咪唑类化合物,在低浓度下即可对肺炎衣原体产生抑制作用。Chlamydia pneumoniae-IN-1 具有抗菌活性,对CV-6菌株的 MIC 为12.6 μM,可用于研究肺部感染。
T11888 LtaS-IN-1

Others; Antibacterial Microbiology/Virology; Others
LtaS-IN-1 是多药耐药粪肠球菌中脂磷壁酸合成的有效抑制剂,可改变细胞壁形态。 LtaS-IN-1 对抗肠球菌属 28 菌株,MIC 值从 0.5 μg/mL 到 64 μg/mL 不等。 LtaS-IN-1 抑制菌株 E1630 和 E1590,MIC 值为 0.5 μg/mL。
Fr13587 7-Chloro-4-(piperazin-1-yl)quinoline

Others Others
7-Chloro-4-(piperazin-1-yl)quinolone 结构是药物化学中的重要支架,它单独或与其他活性药效团混合显示出多种药理特性。7-Chloro-4-(piperazin-1-yl)quinolone 是有效的sirtuin 抑制剂,并且抑制 5-羟色胺的摄取,IC50值为 50 μM。7-Chloro-4-(piperazin-1-yl)quinolone 对恶性疟原虫 D10 和 K1 菌株表现出抗疟疾活性,IC50分别为 1.18 μM 和 0.97 μM。
T18928 Brilliant Black BN

亮黑1,E 151

Others; Virus Protease Microbiology/Virology; Others
Brilliant Black BN (E 151) 是一种偶氮染料和一种食品着色剂。它抑制 EV71 与其细胞脱壳因子亲环蛋白 A 之间的相互作用,是一种很有前途的抗 EV71 感染的抗病毒药物。
T13284L Vapendavir

BTA798

Others Others
Vapendavir is a potent enteroviral capsid binder. Vapendavir has an effective antiviral activity for enterovirus 71 replication (EC50: 0.5-1.4 μM in different EV71 strains).
T13284 Vapendavir diphosphate

BTA798 diphosphate

Others Others
Vapendavir diphosphate is a potent enteroviral capsid binder (CB) and has a potent antiviral activity for enterovirus 71 (EV71) replication (EC50: 0.5-1.4 μM in different EV71 strains).
T71856 FA-613

Others Others
FA-613 is a pyrimidine synthesis inhibitor which exhibits low micromolar antiviral activity against various influenza A and B virus strains, including the highly pathogenic influenza A strains H5N1 and H7N9, enterovirus A71, respiratory syncytial virus, human rhinovirus A, SARS- and MERS-coronavirus.
T32395 Kidamycin

Iyomycin-F

Others Others
Kidamycin, obtained from Streptomyces phaeoverticillatus strains, can interfere with RNA synthesis.
T33690 Nitroscanate

Lopatol,CGA-23654GS,CGA 23654

Others Others
Nitroscanate is an anthelmintic found to be effective in certain strains of parasites in canines.
T39323 Temporin L

Temporin L, a potent antimicrobial peptide, exhibits activity against Gram-negative bacteria and yeast strains, as well as demonstrating antiendotoxin properties.
T40329 Antifungal agent 14

Others Others
Antifungal agent 14 demonstrates potent broad-spectrum antifungal activity, effectively targeting a variety of fungal strains with exceptional minimum inhibitory concentration values.
T26116 Rokitamycin

Others Others
Rokitamycin is a macrolide antibiotic produced from strains of Streptomyces kitasatoensis.
T10902 CWHM-1008

Others Others
CWHM-1008 is an effective oral antimalarial drug. The EC50 values of the drug-sensitive Plasmodium falciparum 3D7 and drug-resistant Dd2 strains are 46 and 21 nM, respectively.
T61869 Metyltetraprole

Others Others
Metyltetraprole is a potent fungicide that demonstrates promising efficacy against sensitive wild-type and G143A mutant strains of Zymoseptoria tritici, as indicated by its low EC50 values of 0.002 ppm. Additionally, this compound exhibits effectiveness against QoI-resistant strains. Metyltetraprole functions by inhibiting the respiratory chain through complex III [1] [2].

化合物

TP0586532
Cat.No: T9318
Synonym:
Target: Others
2′-Deoxy-2′-fluoroguanosine
Cat.No: T38236
Synonym:
Target: Nucleoside Antimetabolite/Analog, Influenza Virus
Cefteram pivoxil
Cat.No: T22287
Synonym: 头孢特仑新戊酯,Ro 19-5248,T-2588
Target: Antibacterial, Antibiotic
5-(3-bromo-4,5-dihydroisoxazol-5-yl)-3-(4-(tert-butyl)phenyl)-1,2,4-oxadiazole
Cat.No: T9858
Synonym:
Target: Parasite
Nifurtimox
Cat.No: T5325
Synonym: 硝呋替莫,BAY-2502,BAY-A-2502
Target: Dehydrogenase, Parasite
CWHM-1552
Cat.No: T10903
Synonym:
Target: Parasite
YM-53403
Cat.No: T29187
Synonym:
Target: Others
Artelinic acid
Cat.No: T10378
Synonym:
Target: Parasite
SB-734117
Cat.No: T9580
Synonym:
Target: HCV Protease
Garenoxacin mesylate hydrate
Cat.No: T7804
Synonym: Garenoxacin mesylate [USAN],加雷沙星甲磺酸盐,BMS284756 (Mesylate hydrate)
Target: Antibacterial
AQ-13 dihydrochloride
Cat.No: T10356
Synonym:
Target: Parasite
anti-TB agent 1
Cat.No: T10329
Synonym:
Target: Antibiotic
BM212
Cat.No: T7342
Synonym:
Target: Antibacterial
Delafloxacin
Cat.No: T4063
Synonym: ABT492,WQ-3034,德拉沙星,RX-3341
Target: Antibacterial, Antibiotic
Artemisone
Cat.No: T14324
Synonym: BAY 44-9585,Artemifone,青蒿酮
Target: Others, Parasite
X-alpha-Gal
Cat.No: T19825
Synonym:
Target: Others
Metaxalone
Cat.No: T1610
Synonym: Skelaxin,Methaxalonum,美他沙酮,Zorane,NSC170959,AHR438
Target: Others
PK150
Cat.No: T7897
Synonym:
Target: Others, Antibacterial
piperacillin
Cat.No: T8620
Synonym: Pipril,Pipracil,哌拉西林,Pipercillin
Target: Antibacterial
GRP-60367
Cat.No: T8701
Synonym:
Target: Others
Anti-Influenza agent 4
Cat.No: T72037
Synonym:
Target: Influenza Virus
Tenofovir exalidex
Cat.No: T28946
Synonym: Tenofovir,HDP-Tenofovir,CMX-157,CMX157,CMX 157
Target: Antiviral
Isepamicin sulfate
Cat.No: T6549
Synonym: Isepamicine (Isepamycin,硫酸异帕米星,Isepamicin Sulphate,Isepacin,sch21420) Sulphate
Target: Antibacterial, Antibiotic
Tetramethylthiuram monosulfide
Cat.No: T22438
Synonym: 一硫化四甲基秋兰姆,TMTM
Target: Others
Azvudine
Cat.No: T14489
Synonym: 4-氨基-1-(4-C-叠氮基-2-脱氧-2-氟-BETA-D-呋喃阿拉伯糖基)-2(1H)-嘧啶酮,FNC,RO-0622
Target: HCV Protease, HBV, HIV Protease, Reverse Transcriptase
Phosphonic acid, [(2R,​3S)​-​3-​methyloxiranyl]​-​, calcium salt (9CI)
Cat.No: T0170
Synonym: phosphonomycin calcium,Fosfomycin calcium,磷霉素钙,phosphomycin calcium
Target: Antibiotic
Povidone iodine
Cat.No: T3114
Synonym: Betadine,聚乙烯吡酮磺,Povidone-iodine,聚乙烯吡咯烷酮碘,Isodine,PVP iodine,iodopovidone,PVP-I
Target: Antibacterial, Antibiotic
N-Desethyl amodiaquine dihydrochloride
Cat.No: T12154L
Synonym:
Target: Parasite
Moxifloxacin
Cat.No: T0331L
Synonym: Avelox,Moxeza,莫西沙星
Target: Others, Antibacterial, Antibiotic
ALX 40-4C acetate
Cat.No: TP1364L
Synonym: ALX 40-4C acetate(143413-49-4 free base)
Target: Apelin receptor, CXCR
Vaborbactam ammonium salt
Cat.No: T17210L
Synonym: RPX7009 ammonium salt,Vaborbactam ammonium salt(1360457-46-0 Free base)
Target: Antibacterial
Nafcillin sodium monohydrate
Cat.No: T1312
Synonym: CL 8491,萘夫西林钠,nafcillin sodium
Target: Antibacterial, Antibiotic
Lanopepden
Cat.No: T11815
Synonym: GSK 1322322,GSK-1322322B,GSK-1322322J
Target: Antibiotic
Fanotaprim
Cat.No: T36692
Synonym:
Target: DHFR
Nitrofural
Cat.No: T9449
Synonym: [(E)-(5-nitrofuran-2-yl)methylideneamino,(E)-2-((5-硝基呋喃-2-基)亚甲基)肼甲酰胺
Target: Antibacterial
Maribavir
Cat.No: T2162
Synonym: BW1263W94,GW257406X,Benzimidavir,马立巴韦,1263W94
Target: Others, HCV Protease
Chlamydia pneumoniae-IN-1
Cat.No: T79088
Synonym:
Target: Antibacterial
LtaS-IN-1
Cat.No: T11888
Synonym:
Target: Others, Antibacterial
7-Chloro-4-(piperazin-1-yl)quinoline
Cat.No: Fr13587
Synonym:
Target: Others
Brilliant Black BN
Cat.No: T18928
Synonym: 亮黑1,E 151
Target: Others, Virus Protease
Vapendavir
Cat.No: T13284L
Synonym: BTA798
Target: Others
Vapendavir diphosphate
Cat.No: T13284
Synonym: BTA798 diphosphate
Target: Others
FA-613
Cat.No: T71856
Synonym:
Target: Others
Kidamycin
Cat.No: T32395
Synonym: Iyomycin-F
Target: Others
Nitroscanate
Cat.No: T33690
Synonym: Lopatol,CGA-23654GS,CGA 23654
Target: Others
Temporin L
Cat.No: T39323
Synonym:
Target:
Antifungal agent 14
Cat.No: T40329
Synonym:
Target: Others
Rokitamycin
Cat.No: T26116
Synonym:
Target: Others
CWHM-1008
Cat.No: T10902
Synonym:
Target: Others
Metyltetraprole
Cat.No: T61869
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T13750 L-Fucitol

L-岩藻糖醇,1-Deoxy-D-galactitol

Others Others
L-Fucitol (1-Deoxy-D-galactitol) 是一种糖醇,从肉豆蔻 (Nutmeg) 中分离得到。
TN1527 (-)-Corynoxidine

Corynoxidine

Antibacterial; AChE; Antifection Microbiology/Virology; Neuroscience
(-)-Corynoxidine 是一种源自 Stephania succifera 块茎的 AChE 抑制剂。 Corynoxidine 对金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌具有不同程度的抗菌活性。
TN3694 Coniferaldehyde

NOS; COX; Nrf2; PKC; Autophagy Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; Immunology/Inflammation; Neuroscience
Coniferaldehyde 能显着抑制酒球菌菌株的生长活力。 Coniferaldehyde 通过诱导血红素加氧酶 1 (HO-1) 发挥抗炎特性。
TN3748 D-Asparagine

D-天冬酰胺,H-D-Asn-OH

Others; Endogenous Metabolite Metabolism; Others
D-Asparagine (H-D-Asn-OH) 是酵母菌株的氮源。 D-Asparagine 是 L-Asparagine 水解的竞争性抑制剂 (Ki = 0.24 mM)。
TN3790 Dehydroabietinol

Pomiferin A,Dehydroabietyl alcohol

Antifection Microbiology/Virology
Dehydroabietinol (Pomiferin A) 在体外抑制红细胞中的氯喹敏感及氯喹抵抗型疟原虫,IC50为26-27 μM.
TN2730 2,5-Dihydroxybenzaldehyde

Gentisaldehyde,2,5-二羟基苯甲醛

Anti-infection; Antibacterial Microbiology/Virology
2,5-Dihydroxybenzaldehyde (Gentisaldehyde) 是一种天然抗微生物剂,可抑制Mycobacterium avium subsp. paratuberculosis 的生长。它还抑制金黄色葡萄球菌菌株,MIC50为 500 mg/L。
TN1524 Continentalic acid

NOS; COX; Antibacterial; Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
Continentalic acid 是来自 Aralia continentalis 的,对金黄色葡萄球菌的 MIC 约为 8-16 µg/mL,包括对甲氧西林敏感的金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌标准菌株。
T7910 4-Methoxybenzaldehyde

大茴香醛,Anisaldehyde,p-Anisaldehyde,Anisic aldehyde,4-Anisaldehyde,4-甲氧基苯甲醛,P-Methoxybenzaldehyde

Others; Endogenous Metabolite Metabolism; Others
4-Methoxybenzaldehyde (p-Anisaldehyde) 是一种天然存在的芳香酚类化合物,存在于许多植物物种中,包括辣根,茴香,八角茴香等。它是一种能够能的神经毒物,已经表现出致死亡率,吸引力和干扰宿主寻求的影响。
T3810 Saikosaponin B2

柴胡皂苷 B2,柴胡皂甙 B2

Others; HCV Protease Microbiology/Virology; Others; Proteases/Proteasome
Saikosaponin B2 是从柴胡根中分离得到的一种活性成分,可抑制 HCV 病毒感染的侵入,有抗癌作用。
T8724 6-Methoxydihydrosanguinarine

Others Others
6-Methoxydihydrosanguinarine 是一种从M. cordata 果实中分离出的生物碱,它对 MCF-7 细胞系(IC50:0.61 μM)和 SF-268 细胞系(IC50:0.54 μM)具有强的细胞毒性。
T1100 Polymyxin B Sulfate

Aerosporin,硫酸多粘菌素 B,PMB,Polymyxin B sulphate,硫酸多粘菌素B,Polymyxin B sulfate (1404-26-8 free base),Poly-RX

Antibacterial; Antibiotic Microbiology/Virology
Polymyxin B Sulfate (Poly-RX) 是一个阳离子型表面活性剂抗生素剂,能够提高细胞膜的渗透性。
T4859 1-Monomyristin

rac-Glycerol 1-myristate,Glyceryl myristate,1-肉豆蔻酸单甘油酯,肉豆寇酸单甘油酯,Monomyristin,2,3-Dihydroxypropyl tetradecanoate

Others; FAAH; Endogenous Metabolite; Antibacterial; Autophagy; Antifungal Autophagy; Metabolism; Microbiology/Virology; Neuroscience; Others
1-Monomyristin (2,3-Dihydroxypropyl tetradecanoate) 是从 Serenoa repens 中提取的,抑制脂肪酸酰胺水解酶活性(IC50=18 μM) 和 2-油酰甘油的水解 (IC50=32 μM)。它对白色念珠菌有抗真菌活性,对金黄色葡萄球菌和聚集性放线菌有抗菌活性。
TN1905 Magnolioside

七叶苷甲基醚,6-甲氧基香豆素-7-0-BETA-D-吡喃葡萄糖苷

Antifection Microbiology/Virology
Magnolioside 是分离自Angelica gigas Nakai(Umbelliferae) 中,对谷氨酸诱导的毒性有显著的神经保护作用。 它显示出对金黄色葡萄球菌 CIP 53.154 的中等抗菌活性。它具有抗疟原虫活性,对氯喹敏感的恶性疟原虫菌株具有强烈的生长抑制作用。
TN3013 4,5-Dimethoxycanthin-6-one

Methylnigakinone

P450; Antibacterial; PDE Metabolism; Microbiology/Virology
4,5-Dimethoxycanthin-6-one 从 Picrasma quassioides BENNET (Simaroubaceae)是一种从 Picrasma quassioides BENNET (Simaroubaceae) 中分离得到生物碱。4,5-Dimethoxycanthin-6-one 是一种有效的、非竞争性的 CYP1A2 介导的 phenacetin O-deethylation 抑制剂(IC50 : 1.7 μM, Ki : 2.6 μM),对环磷酸腺苷(cAMP)磷酸二酯酶有很强的抑制作用。4,5-Dimethoxycanthin-6-one 具有抗菌活性,对金黄色葡萄球菌及其耐药菌株有抑制作用。4,5-Dimethoxycanthin-6-one 对肿瘤细胞株 U937 和 HepG2 具有细胞毒性。
T36585 Isodeoxycholic Acid

isoDCA

Chloride channel; Antibacterial Membrane transporter/Ion channel; Microbiology/Virology
Isodeoxycholic Acid 是一种胆汁酸,由肠道细菌通过脱氧胆酸的表聚作用形成。Isodeoxycholic acid 的临界胶束浓度高于二氯苯甲醚,这表明它的去污活性降低了,而且在抑制七种肠道共生细菌生长方面的活性低于二氯苯甲醚。Isodeoxycholic Acid(0.1%)能抑制几种艰难梭菌菌株在牛磺胆酸诱导下的孢子萌发,并能降低艰难梭菌培养上清对 Vero 细胞的细胞毒性。在高脂饮食诱发肥胖的大鼠模型中,血浆中的Isodeoxycholic acid 水平比正常饮食的大鼠低。
TN4596 Musellactone

Antifection Microbiology/Virology
Musellactone shows different effects against five bacteria strains.
T12712 Reutericyclin

Reutericycline

Others Others
Reutericyclin is a unique tetramic acid, is an antibiotic produced by some strains of Lactobacillus reuteri.
TN3921 Effusanin B

Antifection Microbiology/Virology
Effusanin B shows antibacterial activity. It exhibits DNA-damaging activity in assay which employes DNA-repair deficient (RAD 52Y) and repair proficient (RAD +) yeast strains.
TN6010 Picrasidine S

Picrasidine S shows the potent cytotoxicity against human HeLa cervical, gastric MKN-28, and mouse melanoma B-16 cancer cells, it also shows the potent antibacterial activity against two strains of pathogenic bacteria methicillin-resistant Staphylococcus
TN7530 CBDP

CBD-heptyl,Cannabidiphorol,CBD-C7

Others Others
CBDP, an analytical reference standard classified as a phytocannabinoid, is a bis-homolog of cannabidiol identified in specific Cannabis strains. Intended for research and forensic applications, this compound serves as a crucial reference in scientific studies.
T3831 Licoricone

Antifection Microbiology/Virology
Licoricone exhibits anti-helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains.
TN2271 Thalrugosaminine

Antifection Microbiology/Virology
Thalrugosaminine shows promising antibacterial activity with MIC values of 64-128ug/ml and Staphylococcus species is the most sensitive strains. Thalrugosaminine possesses hypotensive activity in rabbits and is active against Mycobacterium smegmatis.
T16942 Sterigmatocystine

Others Others
Sterigmatocystine is an inhibitor of G1 Phase and DNA synthesis and is used to inhibit p21 activity. Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor.
TN4944 Santamarine

Caspase Apoptosis; Proteases/Proteasome
Santamarine has significant anticancer activity, can inhibit L1210 cells because of its cytotoxic,cytostatic and blocking mitosis and reducing uptake of thymidine. Santamarine and reynosin show bactericidal activity against clinical strains of Mycobacterium tuberculosis.
TQ0072 Warangalone

Scandenolone,攀登鱼藤异黄酮

PKA Tyrosine Kinase/Adaptors
Warangalone is an anti-malarial compound that can inhibit the growth of both strains of parasite 3D7 (chloroquine-sensitive) and K1 (chloroquine-resistant) with IC50s of 4.8 μg/mL and 3.7 μg/mL, respectively.
TMA2418 1-Methoxyphaseollidin

PAFR; Antifection GPCR/G Protein; Microbiology/Virology
1-Methoxyphaseollidin exhibits anti-Helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains. 1-Methoxyphaseollidin may show moderate cytotoxic activity against KB and L1210 cells. 1-Methoxyphaseollidin also shows inhibition of lysoPAF acetyltransferase activity.
TN4716 Oplodiol

Influenza Virus Microbiology/Virology
Oplodiol exhibits noteworthy anti-plasmodial activity against Plasmodium falciparum strains. Oplodiol has a stimulative effect on significantly proliferation and differentiation of culture osteoblasts; it also shows moderate cytotoxic effects on the human
TN1814 Juncusol

6-甲基灯心草二酚,灯心草酚

Caspase; Antifection Apoptosis; Microbiology/Virology; Proteases/Proteasome
Juncusol shows anxiolytic and sedative activities, it shows anxiolytic activity at dosages of 10 mg/kg; it can induce caspase-3-mediated cytotoxicity in HT22 cells. Juncusol has anti-microbial activity, it shows significant activity against MRSA strains.
TN5012 Shizukaol C

HIV Protease; Antifection Microbiology/Virology; Proteases/Proteasome
1. Shizukaol C shows anti-HIV-1 replication activities in both wild-type HIV-1 and two NNRTIs-resistant strains. <br/> 2. Shizukaol C has significant cytotoxicities against C8166 cells. <br/>
T11509 Guanfu base H

Atisinium chloride

Others Others
Guanfu base H is a diterpenoid alkaloid isolated from Aconitum coreanum. It has antiplasmodial activity against the malarial Plasmodium falciparum strains TM4/8.2 (wild type) and K1CB1 (IC50s: 4 μM and 3.6 μM).
TN7516 Isoreserpiline

3-Isoreserpilinic Acid, methyl ester

Others Others
Isoreserpiline, an indole alkaloid discovered in R. tetraphylla, exhibits a range of biological activities. This compound enhances the antibacterial efficacy of nalidixic acid against both nalidixic acid-sensitive and -resistant E. coli strains through a synergistic effect. Additionally, at a dosage of 25 mg/kg, it mitigates amphetamine-induced hyperactivity in mice.
TN7531 CBDB

​Cannabidiol-C4,CBD-C4,Cannabidibutol

Others Others
CBDB, a phytocannabinoid analytical reference standard, is identified in strains of Cannabis and hemp. It is regarded as an impurity in commercial cannabidiol (CBD) extractions from hemp. This compound is designated for research and forensic applications.
T79942 Terpenomycin

Others Others
Terpenomycin是从Nocardia分离物中提取的一种多烯化合物,具有细胞毒性和抗真菌活性。
T13970 Xinjiachalcone A

Others Others
Xinjiachalcone A is a natural product isolated from Glycyrrhiza inflata Batalin. Xinjiachalcone A shows both a low MIC and a strong bactericidal activity against H. pylori(MIC : 12.5 to 50 µM, seventeen H. pylori strains).
TN1526 Corydalmine

P450; Antifection Metabolism; Microbiology/Virology
Corydalmine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains.1-Corydalmine significantly inhibits spore germination of all the fungi at 100 to 1500 ppm. l-Corydalmine also exhibits potent analgesic activity in preclinical models, it is under development as an oral analgesic agent.
T74200 Glicophenone

Others Others
Glicophenone 作为一种抗细菌(antibacterial)剂,对MRSA OM481、MRSA OM505、MRSA OM584、MRSA OM623 以及MSSA 209P的MIC值均为32 μg/mL。
T66935 1-Aminopropan-2-ol

Endogenous Metabolite Metabolism
1-Aminopropan-2-ol 参与枯草芽孢杆菌菌株中的苏氨酸代谢,可作为真菌培养基上的氮源。
TN2278 Torachrysone

决明柯酮

Antifection Microbiology/Virology
Torachrysone shows promising antioxidant activity. Torachrysone, toralactone , aloe-emodin, rhein and emodin show noticeable antibacterial effects on four strains of methicillin-resistant Staphylococcus aureus with a minimum inhibitory concentration of 2-
TN4202 (-)-Heraclenol

Antifection Microbiology/Virology
(-)-Heraclenol shows in vitro anti-plasmodial activity against chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum.(-)-Heraclenol has moderate antibacterial and antifungal activities.
TN4387 Khellactone

Antifection Microbiology/Virology
Khellactone shows antitumor activity,it can suppress the growth of NCI-H460 tumor cells. (+)-4'-cis-Khellactone and (+)-3'-cis-khellactone have antiplasmodial activities, they show notable inhibitory activity against -sensitive strains of with IC(50) values from 1.5 and 2.4 microM.
TN4097 Gancaonin G

Antifection Microbiology/Virology
Gancaonin G shows antibacterial effects on the MRSA strains with MIC values of 16 microg/ml, it also shows more moderate antibacterial activity against Streptococcus mutans.
TN4433 Licoarylcoumarin

cAMP; HIV Protease; Antifection GPCR/G Protein; Microbiology/Virology; Proteases/Proteasome
Licoarylcoumarin is a strong inhibitor of adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase. Licoarylcoumarin has antibacterial effects on the VRE strains; it has anti-HIV activity, and it has inhibitory effects on xanthine oxidase.
T82750 Cellooctaose

Cellooctaose,由8个葡萄糖残基构成的低聚糖,作为低成本的多糖,在发酵中能促进重组乳酸菌的生长。
TN3995 Erythrabyssin II

Antifection Microbiology/Virology
Erythrabyssin II actives against several strains of Staphylococcus and Streptococcus with an MIC range of 0.78-1.56 microg/ml. It inhibits bacterial neuraminidase in a dose-dependent manner with significant inhibition (IC(50)=0.09-3.25 μM).
T22468 1-Deoxymannojirimycin hydrochloride

Others; Influenza Virus; HIV Protease Microbiology/Virology; Others; Proteases/Proteasome
1-Deoxymannojirimycin hydrochloride 是一种选择性的 α1,2-甘露糖苷酶抑制剂,IC50值为 20 μM。它还抑制 HIV-1 毒株,抗病毒活性较差。
TN7525 Parvodicin C2

Antibiotic A40926 B1

Others Others
Parvodicin C2, a glycopeptide antibiotic derived from A. parvosata and part of the parvodicin complex, serves as a component of the A40926 antibiotic complex utilized as a precursor for synthesizing dalbavancin. It exhibits activity against methicillin-sensitive and methicillin-resistant strains of S. aureus, S. epidermidis, S. saprophyticus, S. hemolyticus, and E. faecalis.
T79943 6-C-Methylquercetin-3,4'-dimethyl ether

Antibiotic Microbiology/Virology
6-C-Methylquercetin-3,4'-dimethyl etheris 是一种黄酮醇衍生物,提取自Bauhinia thonningii Schum叶。本化合物对多重耐药的革兰氏阴性细菌及耐甲氧西林金黄色葡萄球菌(MRSA)表现出抗菌活性。
TN7544 (−)-Voacangarine

(−)-Voacristine,NSC 306219

Others Others
(–)-Voacangarine, an indole alkaloid isolated from V. africana, exhibits cytotoxicity towards various cell lines including HepG2, A375, MDA-MB-231, SH-SY5Y, and CT26 with IC50 values of 20 µg/ml. Additionally, it demonstrates cytostatic effects on wild-type S. cerevisiae and is cytotoxic to Δrad3-e5 and Δrad6-1 mutant strains of S. cerevisiae, which have defects in DNA strand break repair and the mutagenic repair pathway, respectively.
T62625 11-O-Methylpseurotin A

Others Others
11-O-Methylpseurotin A为一种(PKS/NRPS)混合聚酮合成酶-非核糖体肽合成酶化合物,其特性为选择性抑制Hof1缺失菌株。
T80351 Maximin 28

Others Others
Maximin 28为源自蟾蜍大脑的抗菌肽,对金黄色葡萄球菌(Staphylococcus aureus)、大肠杆菌(Escherichia coli)及枯草芽孢杆菌(Bacillus subtilis)表现出抗菌活性,其MIC值分别为4.7、9.4、75 μg/mL。
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天然产物

L-Fucitol
Cat.No: T13750
Synonym: L-岩藻糖醇,1-Deoxy-D-galactitol
Target: Others
(-)-Corynoxidine
Cat.No: TN1527
Synonym: Corynoxidine
Target: Antibacterial, AChE, Antifection
Coniferaldehyde
Cat.No: TN3694
Synonym:
Target: NOS, COX, Nrf2, PKC, Autophagy
D-Asparagine
Cat.No: TN3748
Synonym: D-天冬酰胺,H-D-Asn-OH
Target: Others, Endogenous Metabolite
Dehydroabietinol
Cat.No: TN3790
Synonym: Pomiferin A,Dehydroabietyl alcohol
Target: Antifection
2,5-Dihydroxybenzaldehyde
Cat.No: TN2730
Synonym: Gentisaldehyde,2,5-二羟基苯甲醛
Target: Anti-infection, Antibacterial
Continentalic acid
Cat.No: TN1524
Synonym:
Target: NOS, COX, Antibacterial, Prostaglandin Receptor
4-Methoxybenzaldehyde
Cat.No: T7910
Synonym: 大茴香醛,Anisaldehyde,p-Anisaldehyde,Anisic aldehyde,4-Anisaldehyde,4-甲氧基苯甲醛,P-Methoxybenzaldehyde
Target: Others, Endogenous Metabolite
Saikosaponin B2
Cat.No: T3810
Synonym: 柴胡皂苷 B2,柴胡皂甙 B2
Target: Others, HCV Protease
6-Methoxydihydrosanguinarine
Cat.No: T8724
Synonym:
Target: Others
Polymyxin B Sulfate
Cat.No: T1100
Synonym: Aerosporin,硫酸多粘菌素 B,PMB,Polymyxin B sulphate,硫酸多粘菌素B,Polymyxin B sulfate (1404-26-8 free base),Poly-RX
Target: Antibacterial, Antibiotic
1-Monomyristin
Cat.No: T4859
Synonym: rac-Glycerol 1-myristate,Glyceryl myristate,1-肉豆蔻酸单甘油酯,肉豆寇酸单甘油酯,Monomyristin,2,3-Dihydroxypropyl tetradecanoate
Target: Others, FAAH, Endogenous Metabolite, Antibacterial, Autophagy, Antifungal
Magnolioside
Cat.No: TN1905
Synonym: 七叶苷甲基醚,6-甲氧基香豆素-7-0-BETA-D-吡喃葡萄糖苷
Target: Antifection
4,5-Dimethoxycanthin-6-one
Cat.No: TN3013
Synonym: Methylnigakinone
Target: P450, Antibacterial, PDE
Isodeoxycholic Acid
Cat.No: T36585
Synonym: isoDCA
Target: Chloride channel, Antibacterial
Musellactone
Cat.No: TN4596
Synonym:
Target: Antifection
Reutericyclin
Cat.No: T12712
Synonym: Reutericycline
Target: Others
Effusanin B
Cat.No: TN3921
Synonym:
Target: Antifection
Picrasidine S
Cat.No: TN6010
Synonym:
Target:
CBDP
Cat.No: TN7530
Synonym: CBD-heptyl,Cannabidiphorol,CBD-C7
Target: Others
Licoricone
Cat.No: T3831
Synonym:
Target: Antifection
Thalrugosaminine
Cat.No: TN2271
Synonym:
Target: Antifection
Sterigmatocystine
Cat.No: T16942
Synonym:
Target: Others
Santamarine
Cat.No: TN4944
Synonym:
Target: Caspase
Warangalone
Cat.No: TQ0072
Synonym: Scandenolone,攀登鱼藤异黄酮
Target: PKA
1-Methoxyphaseollidin
Cat.No: TMA2418
Synonym:
Target: PAFR, Antifection
Oplodiol
Cat.No: TN4716
Synonym:
Target: Influenza Virus
Juncusol
Cat.No: TN1814
Synonym: 6-甲基灯心草二酚,灯心草酚
Target: Caspase, Antifection
Shizukaol C
Cat.No: TN5012
Synonym:
Target: HIV Protease, Antifection
Guanfu base H
Cat.No: T11509
Synonym: Atisinium chloride
Target: Others
Isoreserpiline
Cat.No: TN7516
Synonym: 3-Isoreserpilinic Acid, methyl ester
Target: Others
CBDB
Cat.No: TN7531
Synonym: ​Cannabidiol-C4,CBD-C4,Cannabidibutol
Target: Others
Terpenomycin
Cat.No: T79942
Synonym:
Target: Others
Xinjiachalcone A
Cat.No: T13970
Synonym:
Target: Others
Corydalmine
Cat.No: TN1526
Synonym:
Target: P450, Antifection
Glicophenone
Cat.No: T74200
Synonym:
Target: Others
1-Aminopropan-2-ol
Cat.No: T66935
Synonym:
Target: Endogenous Metabolite
Torachrysone
Cat.No: TN2278
Synonym: 决明柯酮
Target: Antifection
(-)-Heraclenol
Cat.No: TN4202
Synonym:
Target: Antifection
Khellactone
Cat.No: TN4387
Synonym:
Target: Antifection
Gancaonin G
Cat.No: TN4097
Synonym:
Target: Antifection
Licoarylcoumarin
Cat.No: TN4433
Synonym:
Target: cAMP, HIV Protease, Antifection
Cellooctaose
Cat.No: T82750
Synonym:
Target:
Erythrabyssin II
Cat.No: TN3995
Synonym:
Target: Antifection
1-Deoxymannojirimycin hydrochloride
Cat.No: T22468
Synonym:
Target: Others, Influenza Virus, HIV Protease
Parvodicin C2
Cat.No: TN7525
Synonym: Antibiotic A40926 B1
Target: Others
6-C-Methylquercetin-3,4'-dimethyl ether
Cat.No: T79943
Synonym:
Target: Antibiotic
(−)-Voacangarine
Cat.No: TN7544
Synonym: (−)-Voacristine,NSC 306219
Target: Others
11-O-Methylpseurotin A
Cat.No: T62625
Synonym:
Target: Others
Maximin 28
Cat.No: T80351
Synonym:
Target: Others
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Cat. No. Product Name Species Expression System
TMPY-04483 IRAK4 Protein, Human, Recombinant (His)

IPD1,NY-REN-64,REN64,interleukin-1 receptor-associated kinas...

Human Baculovirus Insect Cells
Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4 contains one death domain and one protein kinase domain. IRAK4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. ...
TMPY-00105 Recombinant Protein G

E. coli
Protein G is a bacterial cell wall protein expressed at the cell surface of certain group C and group G Streptococcal strains. It has affinity for both Fab- and Fc-fragments of human IgG by independent and separate binding sites. Binding to the Fc region of immunoglobulins from several species by a non-immune mechanism exhibits great affinity for almost all mammalian immunoglobulin G (IgG) classes, including all human IgG subclasses (IgG1, IgG2, IgG3 and IgG4) and also rabbit, mouse, and goat Ig...
TMPY-03465 Flagellin Protein, Listeria monocytogenes, Recombinant (His)

flaA

Listeria monocytogenes E. coli
The role of flagella and motility in the attachment of the foodborne pathogen Listeria monocytogenes to various surfaces is mixed with some systems requiring flagella for an interaction and others needing only motility for cells to get to the surface. In nature this bacterium is a saprophyte and contaminated produce is an avenue for infection. Previous studies have documented the ability of this organism to attach to and colonize plant tissue. Motility mutants were generated in three wild ...
TMPJ-00574 RNASE3 Protein, Human, Recombinant (His)

RNase 3,RNS3,ECP,Eosinophil Cationic Protein,RNASE3,Ribonucl...

Human HEK293 Cells
Ribonuclease 3 (RNASE3) is a basic protein that is localized to the eosinophil primary matrix and belongs to the pancreatic ribonuclease family. RNASE3 is released during degranulation of eosinophils. RNASE3 possesses a wide variety of biological activities. RNASE3 interacts with bacterial lipopolysaccharide (LPS) and lipoteichoic acid (LTA). RNASE3 exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. It p...
TMPH-02236 TMPRSS2 Protein, Human, Recombinant (E. coli, His)

Transmembrane protease serine 2,TMPRSS2,Serine protease 10

Human E. coli
Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption and metastasis of prostate cancer cells. In addition, activates trigeminal neurons and contribute to both spontaneous pain and mechanical allodynia....
TMPH-02237 TMPRSS2 Protein, Human, Recombinant (His & Myc)

Serine protease 10,Transmembrane protease serine 2,TMPRSS2

Human HEK293 Cells
Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption and metastasis of prostate cancer cells. In addition, activates trigeminal neurons and contribute to both spontaneous pain and mechanical allodynia....
TMPJ-00751 IgG4 hFc Protein, Human, Recombinant (aa 99-326)

IgG4 Fc,Ig γ-4 chain C region,Ig gamma-4 chain C region

Human HEK293 Cells
As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells, and constitutes 75% of serum immunoglobulins in humans. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC). IgG tetram...

重组蛋白

IRAK4 Protein, Human, Recombinant (His)
Cat.No: TMPY-04483
Species: Human
Expression System: Baculovirus Insect Cells
Recombinant Protein G
Cat.No: TMPY-00105
Species:
Expression System: E. coli
Flagellin Protein, Listeria monocytogenes, Recombinant (His)
Cat.No: TMPY-03465
Species: Listeria monocytogenes
Expression System: E. coli
RNASE3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00574
Species: Human
Expression System: HEK293 Cells
TMPRSS2 Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-02236
Species: Human
Expression System: E. coli
TMPRSS2 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-02237
Species: Human
Expression System: HEK293 Cells
IgG4 hFc Protein, Human, Recombinant (aa 99-326)
Cat.No: TMPJ-00751
Species: Human
Expression System: HEK293 Cells
Cat. No. Product Name Target Signaling Pathways
TMIH-0438 Piperacillin-d5

Piperacillin-d5 是 Piperacillin 的氘代化合物。Piperacillin 的 CAS 号为 61477-96-1。Piperacillin 是半合成青霉素,可以作用于革兰氏阳性和革兰氏阴性需氧和厌氧菌。与其他青霉素相比,它对产生 β-内酰胺酶的菌类表现出更强的活性。
T77211 Sudan I-d5

Sudan I-d5为Sudan I的一种氘代物。作为一种偶氮共轭红色染料(red dye),Sudan I常被作为油、溶剂或抛光剂的添加剂使用。此外,Sudan I能够抑制产气荚膜梭菌及鼠李糖菌的生长。
TMIJ-0232 Piperacillin-d5 (N-ethyl-d5)

Piperacillin-d5 (N-ethyl-d5) 是 Piperacillin 的氘代化合物。Piperacillin 的 CAS 号为 61477-96-1。Piperacillin 是半合成青霉素,可以作用于革兰氏阳性和革兰氏阴性需氧和厌氧菌。与其他青霉素相比,它对产生 β-内酰胺酶的菌类表现出更强的活性。
TMIJ-0059 Moxifloxacin-d4

Moxifloxacin-d4 是 Moxifloxacin 的氘代化合物。Moxifloxacin 的 CAS 号为 151096-09-2。Moxifloxacin 是一种8-甲氧基喹诺酮类口服有效抗菌药物,用于急性细菌性鼻窦炎,慢性支气管炎的急性细菌性加重和感染性肺炎的研究。
TMID-0281 Moxifloxacin-13C-d3

Moxifloxacin-13C-d3 是 Moxifloxacin 的 13C 和氘代化合物。Moxifloxacin 的 CAS 号为 151096-09-2。Moxifloxacin 是一种8-甲氧基喹诺酮类口服有效抗菌药物,用于急性细菌性鼻窦炎,慢性支气管炎的急性细菌性加重和感染性肺炎的研究。
T71293 Nifuroxazide-d4

Nifuroxazide-d4 is intended for use as an internal standard for the quantification of nifuroxazide by GC- or LC-MS. Nifuroxazide is a nitrofuran antibiotic. It is active against strains of the enteropathogenic bacteria C. jejuni, Salmonella, Y. enterocolitica, Shigella, and E. coli. It inhibits quorum sensing and virulence factor production in P. aeruginosa. Nifuroxazide inhibits STAT3 activity in a reporter assay and decreases viability of U266 and INA-6 myeloma cells, which have constitutive S...
T69995 Chlorhexidine-d8 HCl

Chlorhexidine-d8 is intended for use as an internal standard for the quantification of chlorhexidine by GC- or LC-MS. Chlorhexidine is a bis(biguanide) antimicrobial disinfectant and antiseptic agent. It inhibits growth of clinical methicillin-resistant S. aureus (MRSA) isolates (MIC90 = 4 μg/ml). It is also active against canine isolates of MRSA, methicillin-susceptible S. aureus (MSSA), methicillin-resistant S. pseudintermedius (MRSP), and methicillin-susceptible S. pseudintermedius (MSSP; MIC...

同位素标记化合物

Piperacillin-d5
Cat.No: TMIH-0438
Synonym:
Target:
Sudan I-d5
Cat.No: T77211
Synonym:
Target:
Piperacillin-d5 (N-ethyl-d5)
Cat.No: TMIJ-0232
Synonym:
Target:
Moxifloxacin-d4
Cat.No: TMIJ-0059
Synonym:
Target:
Moxifloxacin-13C-d3
Cat.No: TMID-0281
Synonym:
Target:
Nifuroxazide-d4
Cat.No: T71293
Synonym:
Target:
Chlorhexidine-d8 HCl
Cat.No: T69995
Synonym:
Target:
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