|
TMPY-03227
|
CISD1 Protein, Human, Recombinant (His)
ZCD1,CDGSH iron sulfur domain 1,C10orf70,mitoNEET,M...
|
Human
|
E. coli
|
|
Mitochondrial dysfunction is thought to play a significant role in neurodegeneration observed in Parkinson's disease (PD), the loss of mitoNEET (CISD1), an iron-sulfur containing protein that regulates mitochondrial bioenergetics, results in mitochondrial dysfunction and loss of striatal dopamine and tyrosine hydroxylase. CDGSH iron sulfur domain 1 (CISD1, also termed mitoNEET), an iron-containing outer mitochondrial membrane protein, negatively regulates ferroptotic cancer cell death. At the ce... |
|
TMPH-03561
|
lsdB Protein, S. aureus, Recombinant (His & SUMO)
Fur-regulated protein B,Iron-regulated surface dete...
|
Staphylococcus aureus
|
E. coli
|
|
Cell wall-anchored surface receptor that extracts heme from oxidized metHb to enable growth on hemoglobin as a sole iron source. Rapidly extracts heme from hemoglobin and transfers it to IsdA or IsdC, which then relays it to the membrane transporter/IsdEF for internalization. Promotes also resistance to hydrogen peroxide and killing by neutrophils. lsdB Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is ... |
|
TMPH-03407
|
NIFH Protein, Rhizobium leguminosarum, Recombinant (GST & His & Myc)
Nitrogenase iron protein,Nitrogenase reductase,Nitr...
|
Rhizobium leguminosarum
|
E. coli
|
|
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein. NIFH Protein, Rhizobium leguminosarum, Recombinant (GST & His & Myc) is expressed in E. coli expression system with N-10xHis-GST and C-Myc tag. The predicted molecular weight is 35.0 kDa and the accession number is P20623. |
|
TMPH-02460
|
nifH1 Protein, Methanobacterium ivanovii, Recombinant (His & Myc)
Nitrogenase iron protein 1,Nitrogenase reductase,Ni...
|
Methanobacterium ivanovii
|
E. coli
|
|
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein. nifH1 Protein, Methanobacterium ivanovii, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 37.4 kDa and the accession number is P51602. |
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TMPH-00641
|
YTFE Protein, E. coli, Recombinant (GST)
Regulator of cell morphogenesis and NO signaling,Iron
|
E. coli
|
E. coli
|
|
Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions. YTFE Protein, E. coli, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 51.9 kDa and the accession number is P69506. |
|
TMPH-03560
|
lsdA Protein, S. aureus, Recombinant (His & Myc)
Iron-regulated surface determinant protein A,Staphy...
|
Staphylococcus aureus
|
E. coli
|
|
lsdA Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 35.1 kDa and the accession number is Q6GA85. |
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TMPH-01561
|
ISCU Protein, Human, Recombinant (His & Myc)
NifU-like protein,ISCU,Iron-sulfur cluster assembly...
|
Human
|
Baculovirus Insect Cells
|
|
Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic Functions as a cytoplasmic scaffold protein for the de novo synthesis of iron-sulfur clusters in the cytoplasm. |
|
TMPH-00387
|
Toxin CfTX-1 Protein, Chironex fleckeri, Recombinant (His & SUMO)
Toxin CfTX-1
|
Chironex fleckeri
|
E. coli
|
|
Toxin CfTX-1 Protein, Chironex fleckeri, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 65.1 kDa and the accession number is A7L035. |
|
TMPH-02646
|
Erythroferrone Protein, Mouse, Recombinant (His)
Erythroferrone,Myonectin,Erfe,Complement C1q tumor necrosis ...
|
Mouse
|
P. pastoris (Yeast)
|
|
Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake. Erythroferrone Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted m... |
|
TMPY-02707
|
PAH Protein, Human, Recombinant (415 Asn/Asp, His)
phenylalanine hydroxylase,PH,PKU1,PKU
|
Human
|
Baculovirus Insect Cells
|
|
PAH (phenylalanine hydroxylase), also known as PH, belongs to the biopterin-dependent aromatic amino acid hydroxylase family. It contains 1 ACT domain, N-terminal region of PAH is thought to contain allosteric binding sites for phenylalanine and to constitute an "inhibitory" domain that regulates the activity of a catalytic domain in the C-terminal portion of the molecule. In humans, PAH is expressed both in the liver and the kidney, and there is some indication that it may be differentially reg... |
|
TMPK-01170
|
Hepcidin/HAMP Protein, Mouse, Recombinant (GST)
Hamp1,LEAP-1,PLTR,HFE2B,LEAP1,Hepc1,Hepc
|
Mouse
|
E. coli
|
|
Hepcidin, the main regulator of iron metabolism, is synthesized and released by hepatocytes in response to increased body iron concentration and inflammation. Deregulation of hepcidin expression is a common feature of genetic and acquired iron disorders: in Hereditary Hemochromatosis (HH) and iron-loading anemias low hepcidin causes iron overload, while in Iron Refractory Iron Deficiency Anemia (IRIDA) and anemia of inflammation (AI), high hepcidin levels induce iron-restricted erythropoiesis. |
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TMPY-02711
|
Ferritin heavy chain 1/FTH1 Protein, Human, Recombinant
FHC,FTHL6,FTH,PIG15,PLIF,ferritin, heavy polypeptide 1,HFE5
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Human
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E. coli
|
|
FTH1 (ferritin, heavy polypeptide 1) is the heavy subunit of ferritin which is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative dis... |
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TMPJ-00761
|
FTH Protein, Human, Recombinant (His)
FTHL6,Cell proliferation-inducing gene 15 protein,Ferritin h...
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Human
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E. coli
|
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Ferritin heavy polypeptide 1(FTH1), is a ubiquitous intracellular protein which stores iron in a soluble, non-toxic, readily available form. FTH1 has ferroxidase activity and is important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Ferritin is composed of 24 subunits of the light and heavy ferritin chains. It plays a role in delivery of iron to cells and mediates iron uptake in capsule cells of the developing kidney. Variation of... |
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TMPH-00793
|
FtnA Protein, Helicobacter pylori, Recombinant (E. coli, His)
Bacterial non-heme ferritin,ftnA
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Helicobacter pylori
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E. coli
|
|
Iron-storage protein. |
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TMPH-03505
|
Glutaredoxin 4/GrxD Protein, Shigella flexneri, Recombinant (His & SUMO)
grxD,Monothiol glutaredoxin,Glutaredoxin 4
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Shigella flexneri
|
E. coli
|
|
Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. |
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TMPH-00771
|
Ferritin-2 Protein, Glycine max, Recombinant (His & SUMO)
Ferritin-2, chloroplastic,SFerH-2
|
Glycine max
|
E. coli
|
|
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. |
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TMPH-00792
|
FtnA Protein, Helicobacter pylori, Recombinant (His)
Bacterial non-heme ferritin,ftnA
|
Helicobacter pylori
|
Baculovirus Insect Cells
|
|
Iron-storage protein. |
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TMPY-02482
|
Aconitase 1 Protein, Human, Recombinant (His)
HEL60,IRP1,ACONS,aconitase 1, soluble,IREBP,IREBP1,IREB1
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Human
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Baculovirus Insect Cells
|
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Aconitase 1(ACO1) or IRP1 is one member of the aconitase family that contains a diverse group of iron-sulphur(Fe-S) isomerases and two types of iron regulatory protein. Aconitase exits in two forms: one is soluble and the other is mitochondrial. ACO1 is the soluble existing form, and the mitochondrial form is ACO2. Residues from all three N-terminal domains and the larger C-terminal domain contribute to the active site region. When the enzyme is activated, it gains an additional iron atom. ACO1 ... |
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TMPH-02661
|
Frataxin/FXN Protein, Mouse, Recombinant (E. coli, His)
Fxn,Frataxin, mitochondrial
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Mouse
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E. coli
|
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Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activit... |
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TMPH-02660
|
Frataxin/FXN Protein, Mouse, Recombinant (His)
Fxn,Frataxin, mitochondrial
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Mouse
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P. pastoris (Yeast)
|
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Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+); the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activit... |
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TMPH-00016
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Ferredoxin Protein, Acetoanaerobium sticklandii, Recombinant (His & Myc)
Ferredoxin
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Acetoanaerobium sticklandii
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E. coli
|
|
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. |
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TMPH-01301
|
Erythroferrone Protein, Human, Recombinant (His & SUMO)
Myonectin,Erythroferrone,ERFE,Complement C1q tumor necrosis ...
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Human
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E. coli
|
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Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake. |
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TMPY-02582
|
Ferritin light chain Protein, Human, Recombinant (His)
NBIA3,LFTD,MGC71996,ferritin, light polypeptide
|
Human
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E. coli
|
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Ferritin, light polypeptide (FTL) is the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Storage of iron in the tissues occurs in the form of ferritin and hemosiderin. The latter originates from ferritin that has undergone intracellular digestion of its protein shell, leaving the iron core. Ferritin and hemosiderin are components of a continuum. Fer... |
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TMPJ-00378
|
Transferrin Receptor/TFRC Protein, Human, Recombinant (aa 101-760, His)
p90,TfR,T9,Trfr,Transferrin receptor protein 1,TR
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Human
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HEK293 Cells
|
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Transferrin receptor protein 1 (TFRC) belongs to the peptidase M28 family that is synthesized as a 172 amino acid (aa). TFRC regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. It binds one transferrin or HFE molecule per subunit and binds the HLA class II histocompatibility antigen, DR1. It Interacts with SH3BP3 and STEAP3, facilitates TFRC endocytosis in erythroid precursor cells. Cellular uptake of iron o... |
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TMPJ-01062
|
HAMP Protein, Human, Recombinant (GST)
Liver-expressed antimicrobial peptide 1,HEPC,LEAP1,Putative ...
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Human
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E. coli
|
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Hepcidin（HAMP）is a secreted protein that belongs to the hepcidin family.It is expressed in liver, heart and brain. It is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta sheet structure... |
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TMPY-02426
|
UBE2D1 Protein, Human, Recombinant (His)
UBC4/5,E2(17)KB1,ubiquitin-conjugating enzyme E2D 1,UBCH5,UB...
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Human
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E. coli
|
|
Ubiquitin-conjugating enzyme E2 D1 (UBE2D1), a member of human E2 ubiquitin-conjugating enzymes, is closely related to SFT, which is short for stimulator of iron (Fe) transport. In other words, UbcH5A is significantly up-regulated in the liver of iron-overloaded patients with hereditary hemochromatosis, as previously published for SFT. Moreover, a complex of UBE2D1 is critical in maintaining KRAS protein stability and propose that targeting such complex may be a unique strategy to degrade mutant... |
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TMPY-01770
|
HAO1 Protein, Human, Recombinant (His)
GOX1,hydroxyacid oxidase (glycolate oxidase) 1,GOX,HAOX1
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Human
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E. coli
|
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Hydroxyacid oxidase 1, also known as Glycolate oxidase, HAO1, and GOX1, is a member of the FMN-dependent alpha-hydroxy acid dehydrogenase family. HAO1 / GOX1 has 2-hydroxyacid oxidase activity. It is most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate. HAO1 / GOX1 is a liver-specific peroxisomal enzyme that oxidizes glycolate to glyoxylate with the concomitant production of H2O2. In H... |
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TMPH-03371
|
Transferrin Protein, Rat, Recombinant (His & KSI)
Tf,Beta-1 metal-binding globulin,Liver regeneration-related ...
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Rat
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E. coli
|
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Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. Transferrin Protein, Rat, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight ... |
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TMPJ-00513
|
LTF Protein, Human, Recombinant (His)
Lactoferroxin-A,Talalactoferrin,LTF,Lactotransferrin,Lactofe...
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Human
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HEK293 Cells
|
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Lactotransferrin is a member of the transferrin family that transfer iron to the cells and control the level of free iron in the blood and external secretions. Lactotransferrin is a secreted protein and contains two transferrin-like domains. Lactotransferrin can be cleaved into the following four chains: Kaliocin-1, Lactoferroxin-A, Lactoferroxin-B, and Lactoferroxin-C. Lactoferroxin A, Lactoferroxin B, and Lactoferroxin C have opioid antagonist activity. Lactoferroxin A shows preference for mu-... |
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TMPH-03046
|
TBP1 Protein, MenB, Recombinant (His & Myc)
Transferrin-binding protein 1,Transferrin-binding protein A,...
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MenB
|
E. coli
|
|
Neisseria acquires iron by extracting it from serum transferrin (TF) in its human host. Acts as a TF receptor and is required for TF utilization. Binds both apo- and holo-TF, via the TF C-terminus. |
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TMPH-00384
|
Vitellogenin-1 Protein, Chicken, Recombinant (His)
Vitellogenin-1,Vitellogenin I,VTG1,Minor vitellogenin
|
Chicken
|
E. coli
|
|
Precursor of the egg-yolk proteins that are sources of nutrients during early development of oviparous organisms.; Phosvitin is believed to be of importance in sequestering calcium, iron and other cations for the developing embryo. Vitellogenin-1 Protein, Chicken, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 72.4 kDa and the accession number is P87498. |
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TMPH-03746
|
NfuA Protein, E. coli, Recombinant (Avi & His & MBP), Biotinylated
Fe/S biogenesis protein NfuA,nfuA
|
ENT-Escherichia coli
|
E. coli
|
|
Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. NfuA Protein, E. coli, Recombinant (Avi & His & MBP), Biotinylated is expressed in E. coli expression system with N-MBP and C-6xHis-Avi tag. The predicted molecular weight is 68.8 kDa and the accession number is B1X760. |
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TMPH-03705
|
NfuA Protein, Vibrio vulnificus, Recombinant
nfuA,Fe/S biogenesis protein NfuA
|
Vibrio vulnificus
|
E. coli
|
|
Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. NfuA Protein, Vibrio vulnificus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 21.0 kDa and the accession number is Q8DDU2. |
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TMPH-00418
|
Rubredoxin Protein, Clostridium pasteurianum, Recombinant (His & SUMO)
Rubredoxin
|
Clostridium pasteurianum
|
E. coli
|
|
Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule. Rubredoxin Protein, Clostridium pasteurianum, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 22.0 kDa and the accession number is P00268. |
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TMPY-04920
|
ICA Protein, Mouse, Recombinant (His)
|
Mouse
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HEK293 Cells
|
|
INHCA, official full name is inhibitor of carbonic anhydrase, which is a member of the transferrin gene family. Unlike many members of that gene family it does not play a significant role in iron homeostasis but rather is an inhibitor of carbonic anhydrase. Carbonic anhydrase inhibitors are a class of pharmaceuticals that suppress the activity of carbonic anhydrase. |
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TMPH-00621
|
NfuA Protein, E. coli, Recombinant (His)
Fe/S biogenesis protein NfuA,nfuA
|
E. coli
|
E. coli
|
|
Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. NfuA Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25.1 kDa and the accession number is B1X760. |
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TMPJ-00105
|
SOD2 Protein, Human, Recombinant (His)
Superoxide Dismutase [Mn] Mitochondrial,SOD2
|
Human
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HEK293 Cells
|
|
Superoxide Dismutase (SOD2) belongs to the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 transforms toxic superoxide, a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. It is reported that oxidative stress plays an essential role in the development of breast cancer, while SOD2 is one of the primary enzymes that directly convert potential ... |
|
TMPJ-00999
|
UBE2D1 Protein, Human, Recombinant (GST)
Ubiquitin-conjugating enzyme E2(17)KB 1,UB,UbcH5,UBC5A,Stimu...
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Human
|
E. coli
|
|
Ubiquitin-conjugating enzyme E2 D1（UBE2D1）belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transc... |
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TMPH-01080
|
Ceruloplasmin Protein, Human, Recombinant (His & Myc)
CP,Ceruloplasmin,Ferroxidase ceruloplasmin,Cuproxidase cerul...
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Human
|
E. coli
|
|
Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane. Provides Cu(2+) ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1. May also play a role in fetal lung development or pulmonary antioxidant defense. Ceruloplasmin Protein, Human, Recombinant (His & Myc) is expressed in E. co... |
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TMPJ-01142
|
CDO1 Protein, Human, Recombinant (His)
CDO-I,CDO,Cysteine Dioxygenase Type I,CDO1,Cysteine Dioxygen...
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Human
|
E. coli
|
|
Cysteine Dioxygenase Type 1 (CDO1) is a mammalian non-heme iron enzyme that belongs to the cysteine dioxygenase family. CDO1 is highly expressed in the liver and placenta, and has a low expression in heart, brain and pancreas. CDO1 can also be detected in hepatoblastoma HepG2 cells. CDO1 catalyzes the conversion of L-cysteine to cysteine sulfinic acid by incorporation of dioxygen. CDO1 is a vital regulator of cellular cysteine concentrations and has an essential role in maintaining the hepatic c... |
|
TMPY-03109
|
PHYH Protein, Human, Recombinant
PHYH1,RD,PAHX,LN1,phytanoyl-CoA 2-hydroxylase,LNAP1
|
Human
|
E. coli
|
|
PHYH belongs to the family of iron(II)-dependent oxygenases, which typically incorporate one atom of dioxygen into the substrate and one atom into the succinate carboxylate group. PHYH is expressed in liver, kidney, and T-cells, but not in spleen, brain, heart, lung and skeletal muscle. It converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. Defects in PHYH can cause Refsum disease (RD). RD is an autosomal recessive disorder characterized clinically by a tetrad of abnormalities: retinitis pigmentos... |
|
TMPJ-00806
|
HMBS Protein, Human, Recombinant (His)
Pre-Uroporphyrinogen Synthase,PBG-D,Hydroxymethylbilane Synt...
|
Human
|
HEK293 Cells
|
|
Porphobilinogen Deaminase (HMBS) is a member of the HMBS family. PBGD is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. HMBS is involved in the production of heme, which is important for all of the body's organs, although it is most abundant in the blood, bone marrow, and liver. In addition, Heme is an essential component of iron-containing proteins called hemoproteins, including... |
|
TMPJ-00104
|
SOD2 Protein, Human, Recombinant (E. coli, His)
SOD2,Superoxide Dismutase [Mn] Mitochondrial
|
Human
|
E. coli
|
|
Superoxide Dismutase (SOD2) is a number of the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. The SOD2 protein transforms toxic superoxide and a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. Genetic variation in SOD2 is associated with microvascular complications of diabetes type 6 (MVCD6), idiopathic cardiomyopathy (IDC), sporadic motor neuron dis... |
|
TMPJ-00944
|
PPP1CC Protein, Human, Recombinant (His)
PP-1G,Serine/Threonine-Protein Phosphatase PP1-Gamma Catalyt...
|
Human
|
E. coli
|
|
Serine/Threonine-Protein Phosphatase PP1-Υ Catalytic Subunit (PPP1CC) is a member of the PPP phosphatase family. It is essential for cell division, participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. PPP1CC colocalizes with SPZ1 in the nucleus, with URI1 at mitochondrion, Rapidly exchanges between the nucleolar, nucleoplasmic and cytoplasmic compartments. As a cofactor, PPP1CC binds one iron ion and one manganese ion per subunit.. In addition, PPP1C... |
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TMPJ-00817
|
HO-1 Protein, Human, Recombinant
HO,HMOX1,HO-1,Heme Oxygenase 1,HO1
|
Human
|
E. coli
|
|
Heme Oxygenase 1 (HO-1) is an enzyme in endoplasmic reticulum that belongs to the heme oxygenase family. HO-1 cleaves the heme ring at the alpha methene bridge to form Biliverdin. Biliverdin is subsequently converted to Bilirubin by Biliverdin reductase. In physiological state, the highest activity of HO-1 is found in the spleen, where senescent erythrocytes are sequestrated and destroyed. HO-1 activity is highly inducible by its substrate heme and by various non-heme substances such as heavy me... |
|
TMPH-01540
|
Intelectin-1/ITLN1 Protein, Human, Recombinant (His & Myc)
Galactofuranose-binding lectin,Endothelial lectin HL-1,Intel...
|
Human
|
E. coli
|
|
Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner. Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-ulosonic acid (KDO). Binds to glycans from Gram-positive and Gram-negative bacteria, including K.pneumoniae, S.pneumoniae, Y.pestis, P.mirabilis and P.vulgaris. Does not ... |
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TMPJ-01055
|
HBA1 Protein, Human, Recombinant (His)
α-globin,Hemoglobin subunit alpha,HBH,HBA-T3,Alpha-globin,He...
|
Human
|
E. coli
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Hemoglobin subunit alpha 1 (HBA1), also known as α2β2, is a hetero-tetramer consisting of two α and two β subunits held together by non-covalent interactions. Each subunit contains a heme group with an iron atom in the Fe2+ state. Cooperativity of Hemoglobin (Hb) in binding with O2 and allosteric regulatory binding properties with CO2, H+, Cl−, and 2,3-DPG (2,3-bisphosphoglycerate) are based on subunit interactions. HBA1 is the most common type of Hb in adult humans, which mediates the transport... |
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TMPJ-00082
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NGAL/Lipocalin-2 Protein, Mouse, Recombinant (hFc)
Lipocalin-2,SV-40-induced 24P3 protein,Siderocalin LCN2,LCN2...
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Mouse
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HEK293 Cells
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Lipocalin-2, also known as Neutrophil Gelatinase-Associated Lipocalin (NGAL), is a secretory protein of the lipocalin superfamily. Lipocalin-2 contains a signal peptide that enables it to be secreted and form complexes with matrix metalloproteinase-9 (MMP-9) through disulfide bonds. Similar to other lipocalin family members, Lipocalin-2 is involved in diverse cellular processes, including the transport of small hydrophobic molecules, protection of MMP-9 from proteolytic degradation, and cell sig... |
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TMPY-02375
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acnB Protein, E. coli, Recombinant
yacI,yacJ
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E. coli
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E. coli
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Escherichia coli contains two major aconitases (Acns), AcnA and AcnB. They are distantly related monomeric Fe-S proteins that contain different arrangements of four structural domains. acnA is specifically subject to SoxRS-mediated activation, whereas acnB encodes the major aconitase that is synthesized earlier in the growth cycle than AcnA. It is concluded that AcnB is the major citric acid cycle enzyme. Aconitate hydratase 2 (acnB) catalyzes the isomerization of citrate to isocitrate via cis-a... |
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TMPY-02527
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p53R2 Protein, Human, Recombinant (His)
P53R2,MTDPS8A,MTDPS8B,ribonucleotide reductase M2 B (TP53 in...
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Human
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E. coli
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Ribonucleoside reductase subunit M2B, also known as RRM2B or p53R2, is an enzyme belonging to the iron-dependent ribonucleotide reductase (RNR) enzyme family which is essential for DNA synthesis. Ribonucleotide reductase (RNR) is an enzyme that catalyzes the formation of deoxyribonucleotides from ribonucleotides and plays a critical role in regulating the total rate of DNA synthesis so that DNA to cell mass is maintained at a constant ratio during cell division and DNA repair. RRM2B is a phospho... |
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