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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8887 |
2'MeO6MF
|
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
2'MeO6MF 是可透过血脑屏障的α2β1γ2L 和所有含α1的GABAA 受体的正变构调节剂。它也可以直接激活α2β2/3和α2β2/3γ2L GABAA 受体。它具有抗焦虑和促进安定作用。它可提供神经保护作用并改善功能恢复,还可抑制中风诱发的炎症反应。 | |||
T17566 |
Biotin-PEG2-CH2CH2N3
|
Others; PROTAC Linker | Others; PROTAC |
Biotin-PEG2-CH2CH2N3 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T60404 |
NLRP3/AIM2-IN-2
|
AIM2 | Immunology/Inflammation |
NLRP3/AIM2-IN-2是一种新型强效抑制剂,对依赖于 NLRP3和 AIM2炎症体的热扩散具有不同物种特异性影响,IC50为0.2392 ± 0.0233 μ M。 | |||
T67824L |
3-([2,2':5',2'':5'',2'''-quaterthiophen]-5-yl)propan-1-amine FA
|
Others | Others |
3-([2,2':5',2'':5'',2'''-quaterthiophen]-5-yl)propan-1-amine FA 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67824L。 | |||
Fr21265 |
2-Methyl-2H-indazole-3-carboxylic acid
|
Others | Others |
2-Methyl-2H-indazole-3-carboxylic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 Fr21265,CAS号为 34252-44-3。 | |||
T21474 |
Navuridine
AZddU,CS 87,CS-87,AzUrd,3'-Azido-2',3'-dideoxyuridine,AZdU,3'-叠氮-2',3'-双脱氧尿苷 |
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
Navuridine (AZdU) 是一种口服活性的 HIV 逆转录酶抑制剂,半衰期相对较短。 | |||
T73027 |
PARP-2-IN-3
|
Apoptosis; PARP | Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair |
PARP-2-IN-3 作为一种强效 PARP-2 抑制剂(IC50=0.07 μM),具有抗肿瘤活性,能够诱导癌细胞凋亡(apoptosis)和坏死,可用于研究乳腺癌。 | |||
TPL0023 |
(2S,3AS,7aS)-Octahydroindole-2-carboxylic acid
|
Others | Others |
(2S,3AS,7aS)-Octahydroindole-2-carboxylic acid 是有一种有用的有机化合物,已被用于生命科学相关研究。 | |||
T79365 |
TIM-3-IN-2
|
Immunology/Inflammation related | Immunology/Inflammation |
TIM-3-IN-2 是 Tim3 抑制剂,可以抑制TIM-3与PtdSer、CEACAM1和Gal-9的结合,抑制TIM-3发挥作用。TIM-3-IN-2能够逆转TIM-3介导的促炎细胞因子的作用。 | |||
T9034 |
MK2-IN-3
MK2 Inhibitor III |
MAPK | MAPK |
MK2-IN-3 (MK2 Inhibitor III) 是选择性的 MAPKAP-K2 (MK-2)抑制剂(IC50:8.5 nM),能够抑制 U937 细胞及体内 TNFα 的生成。 | |||
T61271 |
MMP2-IN-3
|
MMP | Proteases/Proteasome |
MMP2-IN-3是一种有效的基质金属蛋白酶(MMP-2)抑制剂( IC50 值:31 μM)。MMP2-IN-3 抑制 MMP-9 和 MMP-8 ,其 IC50 分别为 26.6 和 32 μM。 | |||
T73270 |
GSK3-IN-2
|
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
GSK3-IN-2 是一种有效的 GSK3抑制剂。 | |||
T60185 |
FGFR2-IN-3
|
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
FGFR2-IN-3 是一种具有口服活性的选择性 FGFR2抑制剂。 | |||
T11562 |
HIF-2α-IN-3
|
HIF | Angiogenesis; Chromatin/Epigenetic |
HIF-2α-IN-3 是一种 HIF-2α 变构抑制剂,具有抗肿瘤特性,可用于研究心血管疾病。 | |||
T67874 |
PFKFB3-IN-2
|
Glucokinase | Metabolism |
PFKFB3-IN-2是一种6-磷酸果糖-2-激酶/果糖-2,6-二磷酸酶3 (PFKFB3)抑制剂。在体内,对PFKFB3进行反义治疗可降低肿瘤生长速度。 | |||
T11471 |
GSK-3β inhibitor 2
GSK-3β 抑制剂 2,5-Thiazolecarboxamide,2-[2-[(cyclopropylcarbonyl)amino]-4-pyridinyl]-4-methoxy- |
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
GSK-3β inhibitor 2 (5-Thiazolecarboxamide,2-[2-[(cyclopropylcarbonyl)amino]-4-pyridinyl]-4-methoxy-) 是一种特异性的 GSK-3β 抑制剂 (IC50 = 1.1 nM)。 GSK-3β inhibitor 2 可用于阿尔茨海默病的研究。 | |||
T1938 |
FLT3-IN-2
|
FLT | Angiogenesis; Tyrosine Kinase/Adaptors |
FLT3-IN-2 是 FLT3 抑制剂(IC50<1 μM)。 | |||
T64043 |
EZH2-IN-13
|
Histone Methyltransferase | Chromatin/Epigenetic |
EZH2-IN-13 是一种有效的 EZH2 抑制剂,具有潜在的抗癌活性。EZH2-IN-13 可用于研究与 EZH2 活性相关的疾病。 | |||
T60442 |
NLRP3/AIM2-IN-3
|
NOD; AIM2 | Immunology/Inflammation; NF-κB |
NLRP3/AIM2-IN-3 是一种独特的分子,能以物种特异性的方式抑制 NLRP3 和 AIM2 炎性体的激活。它对细胞裂解的 IC50 值为 0.077 ± 0.008 μ M。NLRP3/AIM2-IN-3是一种 NLRP3 和 AIM2 炎症体依赖性细胞裂解的强效抑制剂,对细胞裂解的 IC50 值为 0.077 ± 0.008 μ M。NLRP3/AIM2-IN-3 可抑制 LPS/nigericin 刺激的 THP-1 巨噬细胞的细胞裂解,其 IC50 值为 0.077 ± 0.008 μM。NLRP3/AIM2-IN-3 干扰了 NLRP3 或 AIM2 与桥接蛋白 ASC 的相互作用,抑制了 ASC 的寡聚。 | |||
T78650 |
Nrf2 activator-3
|
Antioxidant; Nrf2 | Immunology/Inflammation; oxidation-reduction |
Nrf2 activator-3为一种高效 Nrf2 激活剂,具有潜在的抗炎抗氧化抗肿瘤活性,可用于研究神经系统疾病和免疫相关疾病。 | |||
T22309 |
2,5-Dimethyl-3(2H)-furanone
2,5-二甲基-3(2H)-呋喃酮,2,5-Dimethyl-2,3-dihydrofuran-3-one |
Others | Others |
2,5-Dimethyl-3(2H)-furanone (2,5-Dimethyl-2,3-dihydrofuran-3-one) 是一种调味物质,无遗传毒性。 | |||
T22730 |
DL-AP3
DL-2-氨基-3-磷丙酸 |
GluR | Neuroscience |
DL-AP3 是一种竞争性 I 族代谢型谷氨酸受体拮抗剂和磷酸丝氨酸磷酸酶抑制剂。 | |||
T7785 |
T-1105
|
Influenza Virus | Microbiology/Virology |
T-1105 是 T-705 的结构类似物,是一种广谱病毒聚合酶抑制剂,在转化为核糖核苷三磷酸代谢物后抑制 RNA 病毒的聚合酶,有抗病毒活性。 | |||
T2265 |
Bimiralisib
5-(4,6-dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine,PQR309,PI3K-IN-2 |
Others; PI3K; S6 Kinase; mTOR | MAPK; Others; PI3K/Akt/mTOR signaling |
Bimiralisib (PI3K-IN-2) 是一种有效的,可渗透脑的 mTOR/PI3K 抑制剂,是一种 mTORC1和 mTORC2抑制剂。它能够抑制 PI3Kα,PI3Kδ,PI3Kβ,PI3Kγ和 mTOR,IC50分别为 33 nM,451 nM,661 nM,708 nM 和 89 nM。 | |||
T50039 |
3-(2-aminopropyl)phenol hydrochloride
|
Others | Others |
3-(2-aminopropyl)phenol hydrochloride 是一种用作分子结构单元的苯乙胺类化合物。它是一种精神活性药物,是5-HT1A、5-HT1B 和5-HT2C 等几种血清素受体的部分激动剂,也是5-HT2A 受体的拮抗剂。 | |||
T64386 |
2,3,5-Trimethylphenol
Isopseudocumenol |
Others | Others |
2,3,5-Trimethylphenol (Isopseudocumenol) 是一种抗增殖化合物,对T. pyriformisp 的pGI50= 0.36。 | |||
T23897 |
CLK1/2-IN-3
CLK1/2 inhibitor 3,CLK1/2-inhibitor-3,CLK1/2 IN 3,CLK1/2IN3 |
CDK | Cell Cycle/Checkpoint |
CLK1/2-IN-3(Cpd-3) 是一种具有高效性和选择性的 CLK1 和 CLK2 抑制剂,抗增殖活性,抑制 CLK1、CLK2、SRPK1、SRPK2、SRPK3 的 的活性。CLK1/2-IN-3 可诱导核斑点扩大,可诱导S6K pre-mRNA选择性剪接和随后抑制多种癌细胞类型细胞生长。 | |||
T60240 |
ALDH1A3-IN-2
|
Dehydrogenase | Metabolism |
ALDH1A3-IN-2 是一种有效的 ALDH1A3 抑制剂,IC50 为 0.30 μM。ALDH1A3-IN-2 具有癌症疾病研究的潜力。 | |||
T7693 |
Thiorphan
|
Neprilysin | Metabolism |
Thiorphan 是选择性neprilysin 抑制剂 (IC50:6.9 nM) 。 | |||
T11874 |
Lp-PLA2-IN-3
|
Phospholipase | Metabolism |
Lp-PLA2-IN-3 是一种强效且具有口服生物活性的脂蛋白相关磷脂酶 A2(Lp-PLA2)抑制剂,对重组人 Lp-PLA2 具有抑制作用,IC50 值为 14 nM。 | |||
T10712 |
CCR2 antagonist 3
AZD-2927,AZD2927 |
CCR | Immunology/Inflammation; Microbiology/Virology |
CCR2 antagonist 3 (AZD-2927) 是 CCR2的拮抗剂。 | |||
T61964 |
RXFP3/4 agonist 2
|
RXFP receptor | GPCR/G Protein |
RXFP3/4 agonist 2 是一种高效的非肽双 RXFP3/4 激动剂,诱导 RXFP3 和 β-arrestin-2 之间的相互作用,可用于研究代谢异常引起的疾病。 | |||
T13360 |
XRK3F2
|
Autophagy | Autophagy |
XRK3F2 是 p62-ZZ 结构域的抑制剂,在体外减弱 MM 诱导的 Runx2 抑制,在体内肿瘤存在的情况下诱导新骨形成和重塑。 | |||
T9344 |
3-Amino-2-oxazolidinone
|
Others; Endogenous Metabolite | Metabolism; Others |
3-Amino-2-oxazolidinone 是一种呋喃唑烷酮的代谢物 (metabolite),可用作检测呋喃唑烷酮残留的一个指标。 | |||
TNU1205 |
2’-Deoxy-N4-methylcytidine
N(3)-Methyl-2'-deoxycytidine |
Nucleoside Antimetabolite/Analog | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
2’-Deoxy-N4-methylcytidine (N(3)-Methyl-2'-deoxycytidine) 是一种嘌呤核苷类似物,具有潜在的抗肿瘤活性,可用于研究细胞凋亡。 | |||
T19925 |
EcDsbB-IN-9
|
Others | Others |
EcDsbB-IN-9 是一种特异性 EcDsbB 抑制剂,靶向革兰氏阴性菌的二硫键形成酶 DsbB。 | |||
T8649 |
TMBIM6 antagonist-1
BAX-inhibitor-1,1-(2-氨基苯基)-3-(3-硝基苯基)-2-丙烯-1-酮,BIA |
mTOR | PI3K/Akt/mTOR signaling |
TMBIM6 antagonist-1 (BAX-inhibitor-1) 是有潜力的TMBIM6拮抗剂,能够抑制 TMBIM6 与 mTORC2 结合,抑制 mTORC2 活性,调节TMBIM6 释放 Ca2+。 | |||
T9607 |
2-Thiopheneacetamide, α-[(2-bromoacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-
|
||
2-Thiopheneacetamide, α-[(2-bromoacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)- 在生命科学相关研究中具有广泛的应用。 | |||
T67696 |
1-(2-fluorophenyl)-3-[5-(2-methoxyphenyl)
|
Others | Others |
1-(2-fluorophenyl)-3-[5-(2-methoxyphenyl)-1,3,4-thiadiazol-2-yl]urea 是一种化合物。 | |||
T8826 |
3-AMINO-1,2,4-TRIAZINE
|
Others | Others |
3-AMINO-1,2,4-TRIAZINE 是一种芳香族生物活性化合物,已用于合成各种药物,包括抗真菌药物氟康唑、抗炎药物布洛芬和抗癌药物紫杉醇;也被用于设计新药,如抗艾滋病药物齐多夫定和抗疟疾药物青蒿素;以及用于合成各种其他化合物,如抗糖尿病药物二甲双胍和抗高血压药物赖诺普利。 | |||
T50122 |
3-Ethyl-1-methyl-2-thioxoimidazolidin-4-one
|
||
3-Ethyl-1-methyl-2-thioxoimidazolidin-4-one 是一种属于咪唑烷酮类化合物的有机化合物,已被用于生命科学相关研究。 | |||
T64318 |
Capecitabine-2',3'-cyclic Carbonate
|
Others | Others |
Capecitabine-2',3'-cyclic Carbonate 是一种抗增殖化合物。 | |||
T60158 |
PBRM1-BD2-IN-3
|
Epigenetic Reader Domain | Chromatin/Epigenetic |
PBRM1-BD2-IN-3 (compound 12) 是一种有效的 PBRM1-BD2 抑制剂,IC50 为 1.1 μM。PBRM1-BD2 Inhibitor 可用于抗癌研究。 | |||
T8351 |
UBP551
3,5-二羟基-2-萘酸 |
NMDAR | Neuroscience |
UBP551 是一种有效的选择性 NMDA 受体调节剂。 | |||
T50090 |
3-(2-phenylethynyl)pyridine
|
Others | Others |
3-(2-phenylethynyl)pyridine 是一种吡啶衍生物,是人体中各种受体的配体,包括多巴胺 D2受体、sigma-1受体和5-HT6受体,已被研究用于治疗各种神经疾病,包括精神分裂症、抑郁症和阿尔茨海默病。 | |||
T9365 |
3-Methyl-2-nitrobenzoic acid
|
Others | Others |
3-Methyl-2-nitrobenzoic acid 在农药等的制备中用作中间体。 | |||
T50035 |
3-methyl-1,2-dihydroquinolin-2-one
|
Epigenetic Reader Domain | Chromatin/Epigenetic |
3-methyl-1,2-dihydroquinolin-2-one 是一个已知的 ATAD2 溴结构域的微摩尔抑制剂。 | |||
T6330 |
Linperlisib
PI3Kδ-IN-2 |
PI3K | PI3K/Akt/mTOR signaling |
Linperlisib (PI3Kδ-IN-2) 是一种有效的,效选择性的,具有口服活性的 PI3Kδ的抑制剂,其 IC50=6.4 nM。 | |||
T8673 |
FMOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CAR
Fmoc-Tpi-OH,FMOC-L-1,2,3,4-四氢-Β-咔啉-3-羧酸 |
Others | Others |
FMOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CAR (Fmoc-Tpi-OH) 是THN 的衍生物。 | |||
T77288 |
KKII5
|
Lipoxygenase | Metabolism |
KKII5 是一种有效的脂氧合酶 LOX-1 抑制剂,IC50 为 19 μM。KKII5 抑制脂质过氧化,增强部分化合物活性中心接收电子的能力。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T10065L |
2',3'-cGAMP sodium
2'-3'-cyclic GMP-AMP sodium |
STING; cGAS | Immunology/Inflammation |
2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) 是细胞天然免疫中第二信使,在 DNA 结合条件下由 cGAMP 合成酶 (cGAS) 催化形成。2',3'-cGAMP sodium 可与 STING 结合形成二聚体,诱导 IFN-β 及其他细胞因子的产生和表达。 | |||
T4751 |
(2R,3R)-Butane-2,3-diol
(2R,3R)-(-)-2,3-Butanediol,levo-2,3-Butanediol,(2R,3R)-(-)-2,3-丁二醇 |
Others; Endogenous Metabolite | Metabolism; Others |
(2R,3R)-Butane-2,3-diol (levo-2,3-Butanediol) 是内源性代谢产物的一种。 | |||
T5901 |
3-Hydroxy-2-methylpyridine
|
Others | Others |
3-Hydroxy-2-methylpyridine 是分离自可可碱提取物,可用于合成嘧啶。 | |||
T5232 |
3-Methyl-2-oxobutanoic acid
3-甲基-2-氧丁酸,2-Oxoisovaleric acid,alpha-Ketoisovaleric acid |
Others; Endogenous Metabolite | Metabolism; Others |
3-Methyl-2-oxobutanoic acid (2-Oxoisovaleric acid) 是大肠杆菌中泛酸的前体。它是由支链氨基酸的不完全分解产生的一种异常代谢物。 | |||
T13495 |
3-Amino-2-piperidinone
Cyclo-ornithine |
Endogenous Metabolite | Metabolism |
3-Amino-2-piperidinone 是来自生物体的代谢物,可用作环状鸟氨酸类似物。 | |||
T5273 |
2-Hydroxy-3-methylbutanoic acid
2-Hydroxy-3-methylbutyric acid,2-Hydroxyisovaleric Acid,2-羟基-3-甲基丁酸,(±)-2-Hydroxyisopentanoic Acid |
Others; Endogenous Metabolite | Metabolism; Others |
2-Hydroxy-3-methylbutyric acid 是一种 GHB 的结构类似物,其中GHB 是一种中枢神经系统中发现的天然物质,也是一种神经药物。 | |||
T8264 |
3-Methyl-2-oxovaleric acid
|
Endogenous Metabolite | Metabolism |
3-Methyl-2-oxovaleric acid 是神经毒素,代谢毒素和酸性原,它是支链氨基酸不完整分解产生的异常代谢物。 | |||
T7923 |
2-Amino-3-hydroxypyridine
|
Others | Others |
2-Amino-3-hydroxypyridine 作为显色试剂用于分光光度法测定锇。 | |||
T4939 |
Indole-3-pyruvic acid
3-(3-吲哚基)-2-氧代丙酸,3-(3-Indolyl)-2-oxopropanoic acid |
Others | Others |
Indole-3-pyruvic acid (3-(3-Indolyl)-2-oxopropanoic acid) 是一种参与Indole-3-acetic acid 生物合成的化合物,Indole-3-acetic acid 是一种植物激素,在调节生长和对环境变化的反应中起重要作用。 | |||
T5986 |
3-Hydroxypicolinic acid
3-羟基-2-吡啶甲酸,Picolinic acid, 3-hydroxy- (6CI,7CI,8CI),2-Carboxy-3-hydroxypyridine |
Endogenous Metabolite | Metabolism |
3-Hydroxypicolinic acid (Picolinic acid, 3-hydroxy- (6CI,7CI,8CI)) 是一种内源性代谢物,属于吡啶甲酸的衍生物。 | |||
T8023 |
2,3,4-Trihydroxybenzoic acid
|
Others | Others |
2,3,4-Trihydroxybenzoic acid 是高效液相色谱法分离酚酸的内参。它是具有抗氧化活性的天然化合物。 | |||
TN7144 |
3,4-Diphenyl-5H-furan-2-one
3,4-diphenyl-2H-furan-5-one,3,4-二苯基-2,5-二氢呋喃-2-酮,3,4-diphenyl-2,5-dihydrofuran-2-one |
Others | Others |
3,4-Diphenyl-5H-furan-2-one (3,4-diphenyl-2H-furan-5-one) 是一种海洋来源的天然产物,存在于Aspergillus flavipes。 | |||
TN7204 |
2-Chlorobenzene-1,3,5-triol
2-Chloro-1,3,5-benzenetriol,2-氯苯-1,3,5-三醇,2-Chlorophloroglucinol,2-chloro-1,3,5-trihydroxybenzene |
Others | Others |
2-Chlorobenzene-1,3,5-triol (2-Chlorophloroglucinol) 是一种海洋来源的天然产物,存在于 Rhabdonia verticillata。 | |||
T4707 |
3-Hydroxyanthranilic acid
3-HYDROXY-2-AMINOBENZOIC ACID,3-羟基-2-氨基苯甲酸 |
Others; Antioxidant; Endogenous Metabolite | Metabolism; Others; oxidation-reduction |
3-Hydroxyanthranilic acid是犬尿氨酸途径中的色氨酸代谢物。它已在人类表皮和膀胱组织中发现,并且在多种生物体液中也已检测到,例如尿液和血液。在细胞内,它主要位于细胞质中。 它存在于从酵母到人类的所有真核生物中。 3-Hydroxyanthranilic acid 具有抗氧化活性。 | |||
TN6798 |
Progoitrin
|
Others | Others |
Progoitrin 是一种硫代葡萄糖苷,与受感染作物中占主导地位。它对甲状腺活性具有抑制作用。 | |||
T3737 |
3-(2,4-Dihydroxyphenyl)propanoic acid
3-(2,4-二羟基苯)丙酸,Hydroumbellic acid,2,4-Dihydroxyhydrocinnamic acid |
Tyrosinase | Proteases/Proteasome |
3-(2,4-Dihydroxyphenyl)propanoic acid (Hydroumbellic acid) 是竞争性酪氨酸酶 (tyrosinase) 抑制剂,可抑制 L-Tyrosine 和 DL-DOPA,IC50和 Ki 分别为 3.02 μM 和 11.5 μM。 | |||
T8050 |
2-Methyltetrahydrofuran-3-one
|
Others | Others |
2-Methyltetrahydrofuran-3-one 是一种烤咖啡的挥发性成分。 | |||
T36818 |
Questiomycin A
|
GPR; Antibacterial | Endocrinology/Hormones; GPCR/G Protein; Microbiology/Virology |
Questiomycin A 是一种在鲜奶油中生产的抗生素,具有抗菌和抗癌活性。 Questiomycin A 抑制细胞保护性 ER 伴侣蛋白 GRP78 的表达。 | |||
TN7153 |
1-(2-hydroxyethyl)thymine
1-(hydroxyethyl)thymine,2,4(1H,3H)-Pyrimidinedione, 1-(2-hydroxyethyl)-5-methyl- |
Others | Others |
1-(2-hydroxyethyl)thymine (2,4(1H,3H)-Pyrimidinedione, 1-(2-hydroxyethyl)-5-methyl-) 是一种海洋来源的天然产物,存在于Zoanthus sp。 | |||
T67047 |
2-Acetyl-3-ethylpyrazine
|
Endogenous Metabolite | Metabolism |
2-Acetyl-3-ethylpyrazine 具有抗肿瘤活性。 | |||
TN7226 |
2-Hydroxy-3-methoxy chalcone
|
||
2-Hydroxy-3-methoxy chalcone 具有抗癌活性,对结肠癌具有抑制作用。 | |||
T8051 |
Bis(2-methyl-3-furyl)disulfide
双(2-甲基-3-呋喃基)二硫,Bis(2-methyl-3-furyl)disulphide |
Others | Others |
Bis(2-methyl-3-furyl)disulphide 是调味剂,能够增强与牛奶相关的产品的自然感,清新感。 | |||
TN7188 |
2-broMobenzene-1,3,5-triol
2-bromo-phloroglucinol,1,3,5-三羟基2-溴苯,Bromophloroglucinol,2-Bromo-1,3,5-benzenetriol |
Others | Others |
2-broMobenzene-1,3,5-triol (Bromophloroglucinol) 是一种海洋来源的天然产物,发现于 Rhabdonia verticillata。 | |||
TN7222 |
2',3',4'-Trimethoxyacetophenone
|
||
2',3',4'-Trimethoxyacetophenone 是制备查耳酮化合物的原料,具有抗炎活性。 | |||
T7991 |
2-Hydroxycinnamic acid
邻羟基肉桂酸(邻香豆酸),(E)-3-(2-羟基苯基)丙烯酸 |
Others; SARS-CoV; HIV Protease | Microbiology/Virology; Others; Proteases/Proteasome |
2-Hydroxycinnamic acid 是从肉桂的甲醇提取物中分离出的一种天然产物,具有光氧化活性。它对HIV/SARS-CoV S 假病毒的感染具有抑制作用,IC50为 0.3 mM。 | |||
T37152 |
3-Methyl-2-cyclopenten-1-one
|
Endogenous Metabolite | Metabolism |
3-Methyl-2-cyclopenten-1-one 可作为食品添加剂,在 2-5 ppm 下可改善肉类和肉制品的风味。添加3-Methyl-2-cyclopenten-1-one 在对雄性Wistar 大鼠口服给药时显示出胃细胞保护活性。 | |||
T7054 |
N-Benzoyl-(2R,3S)-3-phenylisoserine
N-苯甲酰基-(2R,3S)-3-苯基异丝氨酸,taxol side chain |
Antiviral | Immunology/Inflammation |
N-Benzoyl-(2R,3S)-3-phenylisoserine (taxol side chain) 是一种制备用于研究结合位点位置的强效抗癌药物紫杉醇的中间体。 它显示出细胞毒性、抗病毒和免疫调节活性。 | |||
T5379 |
(Rac)-Antineoplaston A10
3-苯基乙酰氨基-2,6-哌啶二酮,Antineoplaston A10 |
Apoptosis; Ras | Apoptosis; GPCR/G Protein; MAPK |
(Rac)-Antineoplaston A10 (Antineoplaston A10) 是 Antineoplaston A10 的消旋体,是一种有抗肿瘤活性的天然产物。Antineoplaston A10 是一种Ras 抑制剂,可研究胶质瘤、淋巴瘤、星形细胞瘤和乳腺癌。 | |||
T7131 |
Antineoplaston A10
3-苯基乙酰氨基-2,6-哌啶二酮,NSC-648539 |
Apoptosis; Endogenous Metabolite; Ras | Apoptosis; GPCR/G Protein; MAPK; Metabolism |
Antineoplaston A10 (NSC-648539) 是存在于人体内的一种天然产物,可研究胶质瘤、淋巴瘤、星形细胞瘤和乳腺癌,是一种 Ras 抑制剂。 | |||
T4237 |
Rubiadin-1-methyl ether
Rubiadin 1-methyl ether,3-羟基-1-甲氧基-2-甲基蒽醌 |
Anti-infection; NF-κB | Microbiology/Virology; NF-κB |
Rubiadin-1-methyl ether (Rubiadin 1-methyl ether) 是一种巴戟天中的蒽醌类化合物,能够抑制 NF-κB p65 的磷酸化和 IκBα 的降解以及减少 p65 的核转位,阻碍破骨细胞的骨吸收。 | |||
T8225 |
2-HYDROXY-3,4-DIMETHOXYBENZOIC ACID
|
Others | Others |
2-HYDROXY-3,4-DIMETHOXYBENZOIC ACID 是一种天然产物。 | |||
TN7187 |
2,4-dibroMobenzene-1,3,5-triol
2,4-dibromophloroglucinol,1,3,5-三羟基2,4-二溴苯,2,4-Dibromo-1,3,5-benzenetriol |
Others | Others |
2,4-dibroMobenzene-1,3,5-triol (2,4-Dibromo-1,3,5-benzenetriol) 是一种海洋来源的天然产物,存在于Rhabdonia verticillata。 | |||
T38373 |
2-heptyl-3-hydroxy-4(1H)-Quinolone
2-heptyl-3-hydroxy-4(1H)-Quinolone,PQS,Pseudomonas Quinolone Signal |
Others | Others |
2-heptyl-3-hydroxy-4(1H)-Quinolone (Pseudomonas Quinolone Signal) 是一种铜绿假单胞菌为应对细胞密度增加而产生的一种法定人数感应信号分子。 它增加了铜绿假单胞菌中lasB 基因的表达,增加代谢物焦蓝蛋白和凝集素PA-IL 的分泌,以及增加铜绿假单胞菌种群的生物膜生产。当使用浓度为40 μM 时,它还会降低铜绿假单胞菌生长介质中的铁含量,并在硫酸铁溶液中充当一种铁螯合剂。 | |||
TN7209 |
3-bromopyrrole-2,5-dione
ZINC13379821,3-溴-1H-吡咯-2,5-二酮,3-Bromo-1H-pyrrole-2,5-dione |
Others | Others |
3-bromopyrrole-2,5-dione (ZINC13379821) 是一种海洋来源的天然产物,存在于 Axinella brevistyla。 | |||
TN7225 |
2'-Hydroxy-3,4-dimethoxychalcone
|
Antioxidant; Parasite | Microbiology/Virology; oxidation-reduction |
2'-Hydroxy-3,4-dimethoxychalcone 是从槐树根分离除的查耳酮化合物,具有抗氧化活性,抑制了多诺瓦尼乳杆菌寄生虫 EC 的细胞内存活50值介于 0.39 和 0.41 μg/mL 之间,可用于研究糖尿病,治疗血吸虫病、疟疾和其它感染。 | |||
TN4221 |
Homoembelin
2,5-dihydroxy-3-nonyl-1,4-benzoquinone |
Antibacterial | Microbiology/Virology |
Homoembelin (2,5-dihydroxy-3-nonyl-1,4-benzoquinone) 是来自 E. ribes 和 C. monocarpus 的色素,具有抗菌效果,可用于耐多药细菌感染的研究。 | |||
T19085 |
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC
POPC,2-油酰-1-棕榈锡甘油-3-磷酸胆碱,1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine,Palmitoyloleoylphosphatidylcholine |
Others | Others |
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (Palmitoyloleoylphosphatidylcholine) 是生物膜的主要成分,是一种磷脂。它用于脂质体的制备以及脂质双层的特性的研究。 | |||
TN1252 |
3'-Geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone
|
Apoptosis | Apoptosis |
3'-Geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone 是一种来自桑叶的黄酮类化合物,具有细胞毒性,可诱导细胞凋亡。 | |||
T3859 |
Isomucronulatol
7,2'-Dihydroxy-3',4'-dimethoxyisoflavan,7,2'-二羟基-3',4'-二甲氧基异黄烷,异短尖剑豆酚 |
Others | Others |
Isomucronulatol 是一种黄酮类化合物,分离自A. membranaceus根。它在体外对 LPS 刺激产生的 IL-12 p40 有抑制作用,具有潜在的抗炎作用。 | |||
T3794 |
Pentagalloylglucose
Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose,1,2,3,4,6-五没食子酰葡萄糖 |
Influenza Virus | Microbiology/Virology |
1,2,3,4,6-O-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) 存在于多种植物中,具有重要的药理作用。Pentagalloylglucose 表现出显著的抗狂犬病病毒 (RABV) 活性。 | |||
TN7161 |
2,3-Dibromomaleinimide
3,4-dibromo-1h-pyrrole-2,5-dione,3,4-Dibromopyrrole-2,5-dione,3,4-二溴-1H-吡咯-2,5-二酮 |
Others | Others |
2,3-Dibromomaleinimide (3,4-Dibromopyrrole-2,5-dione) 是一种海洋来源的天然产物,存在于Axinella brevistyla。 | |||
TN6640 |
1,2,3,4-Tetrahydronorharman-1-one
1,2,3,4-四羟基去甲哈尔满-1-酮,L-Oxonoreleagnine |
Parasite; Antifection | Microbiology/Virology |
1,2,3,4-Tetrahydronorharman-1-one (L-Oxonoreleagnine) 是从印度尼西亚海海绵 Acanthostrongylophora ingens 中分离得到的。 | |||
TN6719 |
Kaempferol-3-O-β-D-glucosyl(1-2)rhamnoside
|
Others | Others |
Kaempferol-3-O-β-D-glucosyl(1-2)rhamnoside 是一种从阿拉伯茉莉中分离出来的天然产物。 | |||
TN2130 |
Manghaslin
槲皮素-3-O-芸香糖-(1→2)-O-鼠李糖苷,Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside |
AChE; Glucosidase | Metabolism; Neuroscience |
Manghaslin (Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside) 是具有抗炎活性的黄酮苷,对 AChE 具有抑制活性,IC50=94.92 µM。 | |||
T36850 |
Curvulin
|
Microtubule Associated | Cytoskeletal Signaling |
Curvulin 是一种植物毒素,可以抑制微管组装,也可以抑制 iNOS 的表达。 | |||
T7959 |
(+)-ISOPINOCAMPHEOL
|
Others | Others |
(+)-ISOPINOCAMPHEOL 是一种天然产物。 | |||
TN7180 |
2-Pyrimidinamine, 4-(5-bromo-1H-indol-3-yl)-
4-(5-溴-1H-吲哚-3-基)嘧啶-2-胺,Meridianin C |
Others | Others |
2-Pyrimidinamine, 4-(5-bromo-1H-indol-3-yl)- (Meridianin C)是一种海洋来源的天然产物,存在于Aplidium meridianum。 | |||
TCS1372 |
Atraric acid
|
Phosphatase; Androgen Receptor | Endocrinology/Hormones; Metabolism |
Atraric acid 衍生物作为一种新的化学先导结构,用于作为 AR 拮抗剂的新型治疗化合物,可用于预防或治疗前列腺疾病。它以剂量依赖性方式抑制 PTP1B 活性,IC50 值为 51.5 uM,表明阿特拉酸具有治疗糖尿病的潜力。 | |||
TN1160 |
1,2,3,6-Tetragalloylglucose
1,2,3,6-Tetra-O-galloyl-β-D-glucose,1,2,3,6-四-O-没食子酰-Β-D-葡萄糖,TeGG |
LDL; UGT | Metabolism |
1,2,3,6-Tetragalloylglucose (TeGG) 是 UDP-葡萄糖醛酸转移酶 1 家族成员,是多肽A1 的抑制剂(Ki:1.68 μM)。 | |||
TN6734 |
Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside
Quercetin 3-O-beta-D-glucosyl-(1->2)-rhamnoside,槲皮素-3-O-葡萄糖基-(1-2)-L-鼠李糖苷,槲皮素 3-O-葡萄糖基 (1→2)鼠李糖苷 |
Others | Others |
Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside (Quercetin 3-O-beta-D-glucosyl-(1->2)-rhamnoside) 是 Shuxuenin 中的一种主要抗氧化剂。 | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00602 |
Influenza A H3N2 (A/Aichi/2/1968) Neuraminidase/NA Protein (His)
NA Protein |
H3N2 | HEK293 Cells |
Influenza A H3N2 (A/Aichi/2/1968) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.8 kDa and the accession number is Q75VQ4.1. | |||
TMPY-00560 |
Influenza A H3N2 (A/Aichi/2/1968) Nucleoprotein/NP Protein (His)
NP Protein |
H3N2 | Baculovirus Insect Cells |
Influenza A H3N2 (A/Aichi/2/1968) Nucleoprotein/NP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is I6TAH8. | |||
TMPY-04779 |
BTN3A2 Protein, Human, Recombinant (His)
BTF3,BT3.2,BTF4,BTN3.2,CD277,buty... |
Human | HEK293 Cells |
The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A2 is overexpressed in gastric tumors, and deletion of BTN3A2 inhibited proliferation, migration, and invasion of gastric cancer cells. The butyrophilin 3 (BTN3) receptors are implicated in the T lymphocytes regulation and present a wide plasticity in mammals. A thorough phylogenetic analysis reveals a concerted... | |||
TMPY-01524 |
Influenza A H3N2 (A/Aichi/2/1968) Hemagglutinin/HA Protein (HA1+HA2, uncleaved) (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | HEK293 Cells |
Influenza A H3N2 (A/Aichi/2/1968) Hemagglutinin/HA Protein (HA1+HA2, uncleaved) (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is P03437. | |||
TMPY-02521 |
HIST3H2A Protein, Human, Recombinant
histone cluster 3, H2a,MGC3165 |
Human | E. coli |
Histones are a complex family of highly conserved basic proteins responsible for packaging chromosomal DNA into nucleosomes. There are subtype diversities: H1, H2A, H2B, and H3 or H4. It has become more and more evident that histone modifications are key players in the regulation of chromatin states and dynamics as well as in gene expression. Therefore, histone modifications and the enzymatic machinery that set them are crucial regulators that can control cellular proliferation, differentiation,... | |||
TMPY-02237 |
KIR2DL3 Protein, Human, Recombinant (His)
NKAT2,MGC129943,KIR-K7c,NKAT2B,CU464054.1,NKAT,KIR-... |
Human | HEK293 Cells |
KIR2DL3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.9 kDa and the accession number is Q32WE4. | |||
TMPY-01525 |
Influenza A H3N2 (A/Aichi/2/1968) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | HEK293 Cells |
Influenza A H3N2 (A/Aichi/2/1968) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is P03437. | |||
TMPY-01621 |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His)
TIMD-3,hepatitis A virus cellular receptor 2,HAVcr-... |
Human | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.3 kDa and the accession number is AAL65157.1. | |||
TMPY-05442 |
KIR2DL3 Protein, Human, Recombinant (hFc)
KIR-K7b,CU464054.1,killer cell immunoglobulin like receptor,... |
Human | HEK293 Cells |
KIR2DL3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.6 kDa and the accession number is Q32WE4. | |||
TMPY-05227 |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated
TIMD3,hepatitis A virus cellular receptor 2,CD3... |
Human | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.3 kDa and the accession number is AAL65157.1. | |||
TMPK-00887 |
KIR3DL2 Protein, Human, Recombinant (His & Avi)
KIR3DL2,p140,NKAT4,NKAT4A,NKAT4B,CL-5,CD158k,NKAT-4 |
Human | HEK293 Cells |
KIR3DL2 is a member of the killer cell immunoglobulin-like receptor (KIR) family that was initially identified at the surface of natural killer (NK) cells. KIR3DL2, also known as CD158k, is expressed as a disulfide-linked homodimer. Each chain is composed of three immunoglobulin-like domains and a long cytoplasmic tail containing two immunoreceptor tyrosine-based inhibitory motifs. KIR3DL2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The pred... | |||
TMPY-02336 |
Influenza A H3N2 (A/Babol/36/2005) Neuraminidase/NA Protein (His)
NA Protein |
H3N2 | HEK293 Cells |
Influenza A H3N2 (A/Babol/36/2005) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.6 kDa and the accession number is C0LU95. | |||
TMPY-00152 |
Influenza A H3N2 (A/Texas/50/2012) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | Baculovirus Insect Cells |
Influenza A H3N2 (A/Texas/50/2012) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.3 kDa. | |||
TMPY-05205 |
Influenza A H3N2 (A/Hong Kong/4801/2014) Neuraminidase/NA Protein (His)
NA Protein |
H3N2 | HEK293 Cells |
Influenza A H3N2 (A/Hong Kong/4801/2014) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.5 kDa. | |||
TMPY-00113 |
Influenza A H3N2 (A/Wisconsin/67/2005) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | Baculovirus Insect Cells |
Influenza A H3N2 (A/Wisconsin/67/2005) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.3 kDa and the accession number is B4URC5. | |||
TMPY-00957 |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | HEK293 Cells |
Influenza A H3N2 (A/Brisbane/10/2007) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is A8W8K8. | |||
TMPY-04784 |
Influenza A H3N2 (A/Switzerland/9715293/2013) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | Baculovirus Insect Cells |
Influenza A H3N2 (A/Switzerland/9715293/2013) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.1 kDa. | |||
TMPY-04783 |
Influenza A H3N2 (A/Wuhan/359/1995) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | Baculovirus Insect Cells |
Influenza A H3N2 (A/Wuhan/359/1995) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is J9R649. | |||
TMPY-06066 |
Influenza A H3N2 (A/Kansas/14/2017) Neuraminidase/NA Protein (His)
NA Protein |
H3N2 | Baculovirus Insect Cells |
Influenza A H3N2 (A/Kansas/14/2017) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.6 kDa and the accession number is A0A2L2FIU4. | |||
TMPY-00278 |
Influenza A H3N2 (A/Victoria/361/2011) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | Baculovirus Insect Cells |
Influenza A H3N2 (A/Victoria/361/2011) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.4 kDa and the accession number is L0HR89. | |||
TMPY-02612 |
Influenza A H3N2 (A/Perth/16/2009) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | HEK293 Cells |
Influenza A H3N2 (A/Perth/16/2009) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is C6KNH7. | |||
TMPY-05920 |
Influenza A H3N2 (A/Kansas/14/2017) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | HEK293 Cells |
Influenza A H3N2 (A/Kansas/14/2017) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is A0A346MM15. | |||
TMPY-06058 |
Influenza A H3N2 (A/Hong Kong/2671/2019) Nucleoprotein/NP Protein (His)
NP Protein |
H3N2 | Baculovirus Insect Cells |
Influenza A H3N2 (A/Hong Kong/2671/2019) Nucleoprotein/NP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.3 kDa. | |||
TMPY-05825 |
Influenza A H3N2 (A/Hong Kong/4801/2014) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | Baculovirus Insect Cells |
Influenza A H3N2 (A/Hong Kong/4801/2014) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.26 kDa. | |||
TMPY-05921 |
Influenza A H3N2 (A/Hong Kong/2671/2019) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | HEK293 Cells |
Influenza A H3N2 (A/Hong Kong/2671/2019) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.1 kDa. | |||
TMPY-06057 |
Influenza A H3N2 (A/Hong Kong/45/2019) Nucleoprotein/NP Protein (His)
NP Protein |
H3N2 | Baculovirus Insect Cells |
Influenza A H3N2 (A/Hong Kong/45/2019) Nucleoprotein/NP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.3 kDa. | |||
TMPY-04658 |
Influenza A H3N2 (A/Switzerland/9715293/2013) Hemagglutinin/HA0 Protein
Harvey rat sarcoma viral oncogene homolog |
H3N2 | Baculovirus Insect Cells |
Influenza A H3N2 (A/Switzerland/9715293/2013) Hemagglutinin/HA0 Protein is expressed in Baculovirus insect cells. The predicted molecular weight is 61.8 kDa. | |||
TMPY-04293 |
Influenza A H3N2 (A/Perth/16/2009) Hemagglutinin/HA0 Protein
Harvey rat sarcoma viral oncogene homolog |
H3N2 | Baculovirus Insect Cells |
Influenza A H3N2 (A/Perth/16/2009) Hemagglutinin/HA0 Protein is expressed in Baculovirus insect cells. The predicted molecular weight is 61.9 kDa and the accession number is C6KNH7. | |||
TMPY-00012 |
Influenza A H3N2 (A/Texas/50/2012) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | HEK293 Cells |
Influenza A H3N2 (A/Texas/50/2012) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.1 kDa and the accession number is R4L4F3. | |||
TMPY-05826 |
Influenza A H3N2 (A/Singapore/INFIMH-16-0019/2016) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | HEK293 Cells |
Influenza A H3N2 (A/Singapore/INFIMH-16-0019/2016) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.27 kDa. | |||
TMPY-03937 |
Influenza A H3N2 (A/Hong Kong/1/1968) Hemagglutinin/HA Protein (aa 1-530, His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | Baculovirus Insect Cells |
Influenza A H3N2 (A/Hong Kong/1/1968) Hemagglutinin/HA Protein (aa 1-530, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59 kDa and the accession number is Q91MA7.1. | |||
TMPY-04802 |
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc)
kinase insert domain receptor,CD309,VEGFR2,FLK1,Flk... |
Human | HEK293 Cells |
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.4 kDa and the accession number is P35968-1. | |||
TMPY-04796 |
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His)
FLK1,kinase insert domain receptor,CD309,VEGFR2,Flk... |
Human | HEK293 Cells |
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.8 kDa and the accession number is P35968-1. | |||
TMPY-04849 |
Influenza A H3N2 (A/Aichi/2/1968) Neuraminidase/NA Protein
NA Protein |
H3N2 | HEK293 Cells |
Influenza A H3N2 (A/Aichi/2/1968) Neuraminidase/NA Protein is expressed in HEK293 mammalian cells. The predicted molecular weight is 52.2 kDa and the accession number is Q75VQ4.1. | |||
TMPY-04795 |
VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, His)
kinase insert domain receptor,VEGFR2,FLK1,Flk-1,CD3... |
Human | HEK293 Cells |
VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.9 kDa and the accession number is P35968-1. | |||
TMPY-04794 |
VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, hFc)
VEGFR,kinase insert domain receptor,Flk-1,VEGFR2,FLK1,CD... |
Human | HEK293 Cells |
VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.5 kDa and the accession number is P35968-1. | |||
TMPY-00282 |
Influenza A H3N2 (A/Aichi/2/1968) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | Baculovirus Insect Cells |
Influenza A H3N2 (A/Aichi/2/1968) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59 kDa and the accession number is P03437.1. | |||
TMPJ-00571 |
UBE2D3 Protein, Human, Recombinant
Ubiquitin-protein ligase D3,Ubiquitin-conjugating e... |
Human | E. coli |
UBE2D3 is an enzyme that belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. | |||
TMPY-05898 |
Influenza A H3N2 (A/swine/Miyazaki/2/2013) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H3N2 | HEK293 Cells |
Influenza A H3N2 (A/swine/Miyazaki/2/2013) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is A0A077KEB1. | |||
TMPY-02448 |
Influenza A H3N2 Neuraminidase/NA Protein
NA Protein |
H3N2 | HEK293 Cells |
Influenza A H3N2 Neuraminidase/NA Protein is expressed in HEK293 mammalian cells. The accession number is C0LU95. | |||
TMPY-05428 |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc)
HAVcr-2,KIM-3,Tim-3,TIMD3,HAVCR2,... |
Human | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.6 kDa and the accession number is Q8TDQ0-1. | |||
TMPH-01589 |
KIR2DS3 Protein, Human, Recombinant (His)
KIR2DS3,Natural killer-associated transcript 7,Kill... |
Human | P. pastoris (Yeast) |
Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells. | |||
TMPY-03051 |
B3GNT2 Protein, Human, Recombinant (hFc)
B3GNT-2,B3GNT,UDP-GlcNAc:betaGal beta-1, |
Human | HEK293 Cells |
B3GNT2 belongs to the beta-1,3-N-acetylglucosaminyltransferase family. It is a type II transmembrane protein that prefers the substrate of lacto-N-neotetraose. Alternative splicing produced 2 isoforms of the human protein. B3GNT2 catalyzes the initiation and elongation of poly-N- acetyllactosamine chains. Enzymatic activities of some glycosyltransferases are markedly increased via complex formation with other transferases or cofactor proteins. B3GNT2 and beta3Gn-T8 can form a heterodimer in vitr... | |||
TMPH-02891 |
SCGB3A2 Protein, Mouse, Recombinant (GST & His)
Uteroglobin-related protein 1,Secretoglobin family 3 |
Mouse | E. coli |
SCGB3A2 Protein, Mouse, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 43.2 kDa and the accession number is Q920H1. | |||
TMPY-03677 |
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (hFc)
Tim3,TIM-3,hepatitis A virus cellular rece... |
Mouse | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.9 kDa and the accession number is AAL65156.1. | |||
TMPY-01933 |
CHI3L2 Protein, Human, Recombinant (His)
YKL-39,CHIL2,chitinase 3 like 2,YKL3 |
Human | HEK293 Cells |
Chondrocyte protein 39 (YKL-39), also known as Chitinase 3-like 2 (CHI3L2), is a secretory protein of articular chondrocytes belonging to the glycosyl hydrolase 18 family. Its highest expression is in chondrocytes, followed by synoviocytes, lung and heart. YKL-39/CHI3L2 is not detected in spleen, pancreas, and liver. YKL-39/CHI3L2 may also be expressed in developing brain and placenta. YKL-39/CHI3L2, a cartilage-related protein, is found to induce arthritis accompanied by pathologic changes in b... | |||
TMPK-00224 |
BTN3A2 Protein, Human, Recombinant (His & Avi)
FLJ40011,BTN3A2,BTF4,CD277,BT3.2,BTF3<... |
Human | HEK293 Cells |
BTN3A2/BT3.2 butyrophilin mRNA expression by tumoral cells was previously identified as a prognostic factor in a small cohort of high grade serous epithelial ovarian cancer (HG-EOC).In conclusion, BT3.2 protein is a potential prognostic biomarker for the identification of HG-EOC patients with better outcome. In contrast, high CD206 /CD68 expression is associated with high risk of disease progression. | |||
TMPY-05463 |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (mFc)
HAVCR2,TIM3,CD366,TIMD3,hepatitis... |
Human | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 46.2 kDa and the accession number is Q8TDQ0-1. | |||
TMPJ-00189 |
TIM-3/KIM-3/HAVCR2 Protein, Cynomolgus, Recombinant (His)
HAVCR2,Tim-3,TIM3,T cell immunoglobulin an... |
Cynomolgus | HEK293 Cells |
T cell immunoglobulin and mucin domain 3 is a member of the TIM family of immune regulating molecules. Mature cynomolgus TIM3 consists of a 182 amino acid (aa)extracellular domain (ECD), a 21 aa transmembrane segment, and a 78 aa cytoplasmic tail. TIM3 is up-regulated on several populations of activated myeloid cells (macrophage, monocyte, dendritic cell, microglia, mast cell) and T cells (Th1, CD8+, NK, Treg). Its binding to Galectin9 induces a range of immunosuppressive functions which enhance... | |||
TMPJ-00624 |
TIM-3/KIM-3/HAVCR2 Protein, Marmoset, Recombinant (His)
Tim3,HAVcr-2,Timd3,Hepatitis A virus cellu... |
Marmoset | HEK293 Cells |
TIM-3/KIM-3/HAVCR2 Protein, Marmoset, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 30-45 KDa and the accession number is F7I881. | |||
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Cat. No. | Product Name | Target | Signaling Pathways |
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TMID-0157 |
Indole-3-butyric acid-d2
|
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Indole-3-butyric acid-d2 是 Indole-3-butyric acid 的氘代化合物。Indole-3-butyric acid 的 CAS 号为 133-32-4。3-Indolebutyric acid 是一种植物生长素。 它能够促进草本植物和木本观赏植物生根,并用于提高果实率。 | |||
TMIJ-0197 |
Tauroursodeoxycholic-2,2,3,4,4-d5 Acid
|
||
Tauroursodeoxycholic-2,2,3,4,4-d5 Acid 是 Tauroursodeoxycholic Acid 的氘代化合物。Tauroursodeoxycholic Acid 的 CAS 号为 14605-22-2。Tauroursodeoxycholate,又称 ursodoxicoltaurine,是一种高度亲水性的三级胆汁酸,在人体内以低浓度产生。Tauroursodeoxycholate 是 ursodeoxycholic acid 更亲水的形式,而 ursodeoxycholic acid 是人类体内自然产生的更丰富的胆汁酸。Tauroursodeoxycholate 正在研究用于几种疾病,如原发性胆汁性肝硬化(PBC)、胰岛素抵抗、淀粉样变性、囊性纤维化、胆汁淤滞和肌萎缩性侧索硬化症。 | |||
TMID-0172 |
(-)-2-Methyl Isoborneol-d3
|
||
(-)-2-Methyl Isoborneol-d3 是 (-)-2-Methyl Isoborneol 的氘代化合物。(-)-2-Methyl Isoborneol 的 CAS 号为 68330-43-8。 | |||
TMIJ-0101 |
DL-Alanine-2,3,3,3-d4
|
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DL-Alanine-2,3,3,3-d4 是 DL-Alanine 的氘代化合物。DL-Alanine 的 CAS 号为 302-72-7。DL-Alanine 是一种氨基酸,是L-和D-丙氨酸的外消旋化合物。DL-Alanine 与硝酸银水溶液一起用于纳米颗粒生成时常作为还原剂和封端剂。DL-Alanine 是一种甜味剂,可把它位与甘氨酸和糖精钠归为一类。DL-Alanine 在组织和肝脏之间的葡萄糖-丙氨酸循环中起重要作用。DL-Alanine 可用于研究 Cu、Zn、Cd 等过渡金属螯合。 | |||
TMIJ-0417 |
2,4-D-d3
|
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2,4-D-d3 是 2,4-D 的氘代化合物。2,4-D 的 CAS 号为 94-75-7。2,4-Dichlorophenoxyacetic acid 是一种合成生长素,用作植物生长调节剂,也用作植物细胞培养基中的补充剂。它是除草剂中的一种活性成分,用于破坏肌动蛋白细胞骨架,以控制根系伸长和细胞生成。 | |||
TMID-0215 |
2-Butanone 2,4-Dinitrophenylhydrazone-3,5,6-d3
|
||
2-Butanone 2,4-Dinitrophenylhydrazone-3,5,6-d3 是 2-Butanone 2,4-Dinitrophenylhydrazone 的氘代化合物。2-Butanone 2,4-Dinitrophenylhydrazone 的 CAS 号为 958-60-1。 | |||
T37119 |
1,2,3-Trioctanoyl-rac-glycerol-13C3
1,2,3-Trioctanoyl-rac-glycerol-13C3 |
||
1,2,3-Trioctanoyl-rac-glycerol-13C3 is intended for use as an internal standard for the quantification of 1,2,3-trioctanoyl-rac-glycerol by GC- or LC-MS. 1,2,3-Trioctanoyl-rac-glycerol is a triacylglycerol that contains octanoic acid at the sn-1, sn-2, and sn-3 positions. Dietary administration of 1,2,3-trioctanoyl-rac-glycerol increases hippocampal levels of the glycolytic metabolites glucose 6-phosphate, fructose 6-phosphate, and β-hydroxybutyrate and the seizure threshold in the 6 Hz psychomo... | |||
TMIH-0036 |
2-Furoic Acid-d3
|
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2-Furoic Acid-d3 是 2-Furoic Acid 的氘代化合物。 | |||
TMID-0101 |
2-Phenylethyl Acetate-d3
|
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2-Phenylethyl Acetate-d3 是 2-Phenylethyl Acetate 的氘代化合物。2-Phenylethyl Acetate 的 CAS 号为 103-45-7。 | |||
TMIJ-0442 |
(1'S,2'S)-Nicotine-1'-Oxide-d3
|
||
(1'S,2'S)-Nicotine-1'-Oxide-d3 是 (1'S,2'S)-Nicotine-1'-Oxide 的氘代化合物。(1'S,2'S)-Nicotine-1'-Oxide 的 CAS 号为 51095-86-4。 | |||
TMIJ-0027 |
3-Methyl-2-quinoxalinecarboxylic Acid-d4
MQCA-d4 |
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3-Methyl-2-quinoxalinecarboxylic Acid-d4 是 3-Methyl-2-quinoxalinecarboxylic Acid 的氘代化合物。3-Methyl-2-quinoxalinecarboxylic Acid 的 CAS 号为 74003-63-7。3-Methyl-2-quinoxalinecarboxylic acid 在生命科学相关研究中具有广泛的应用。 | |||
TMIH-0086 |
Amifampridine-d3 2HCl
|
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Amifampridine-d3 2HCl 是 Amifampridine 2HCl 的氘代化合物。Amifampridine 2HCl 的 CAS 号为 54-96-6。Amifampridine 可用于罕见肌肉疾病的研究。 | |||
TMIH-0037 |
2-Methylpropanedioic acid-d3
methyl-d3-malonic acid |
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2-Methylpropanedioic acid-d3 是 2-Methylpropanedioic acid 的氘代化合物。2-Methylpropanedioic acid 的 CAS 号为 516-05-2。Methylmalonic acid 是癌症患者缺乏维生素 B-12的指标。 | |||
TMIJ-0418 |
2,4-Dimethylphenol-d3 (3,5,6-d3)
|
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2,4-Dimethylphenol-d3 (3,5,6-d3) 是 2,4-Dimethylphenol 的氘代化合物。2,4-Dimethylphenol 的 CAS 号为 105-67-9。 | |||
TMIH-0039 |
3 Hydroxy Midostaurin Epimer 2-d5
CGP52421 Epimer 2-d5 |
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3 Hydroxy Midostaurin Epimer 2-d5 是 3 Hydroxy Midostaurin Epimer 2 的氘代化合物。3 Hydroxy Midostaurin Epimer 2 的 CAS 号为 155848-20-7。 | |||
TMIJ-0415 |
2-Chlorophenol-d4 (3,4,5,6-d4)
|
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2-Chlorophenol-d4 (3,4,5,6-d4) 是 2-Chlorophenol 的氘代化合物。2-Chlorophenol 的 CAS 号为 95-57-8。 | |||
TMIH-0050 |
3-phenylpropanoic-2,2-d2 acid
|
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3-phenylpropanoic-2,2-d2 acid 是 3-phenylpropanoic-2,2 acid 的氘代化合物。 | |||
TMIH-0035 |
2-Furamide-3,4,5-d3
|
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2-Furamide-3,4,5-d3 是 2-Furamide-3,4,5 的氘代化合物。 | |||
TMIH-0191 |
dimethyl 2-(methyl-d3)malonate
|
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dimethyl 2-(methyl-d3)malonate 是 dimethyl 2-(methyl)malonate 的氘代化合物。dimethyl 2-(methyl)malonate 的 CAS 号为 516-05-2。Methylmalonic acid 是癌症患者缺乏维生素 B-12的指标。 | |||
TMIH-0033 |
2-chloro-6-methylbenzoic acid-d3
|
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2-chloro-6-methylbenzoic acid-d3 是 2-chloro-6-methylbenzoic acid 的氘代化合物。2-chloro-6-methylbenzoic acid 的 CAS 号为 21327-86-6。 | |||
TMIJ-0517 |
3,5-Dinitrosalicylhydrazide-15N2
|
||
3,5-Dinitrosalicylhydrazide-15N2 是 3,5-Dinitrosalicylhydrazide 的 13C 和氘代化合物。 | |||
TMID-0029 |
Succinic-2,2,3,3-d4 Acid
|
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Succinic-2,2,3,3-d4 Acid 是 Succinic Acid 的氘代化合物。Succinic Acid 的 CAS 号为 110-15-6。Succinic acid 是无氧代谢的发酵产物,也是三羧酸循环的中间产物。 | |||
TMIH-0031 |
25-Hydroxy vitamin D2-d3
|
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25-Hydroxy vitamin D2-d3 是 25-Hydroxy vitamin D2 的氘代化合物。 | |||
TMID-0261 |
Indole-2,4,5,6,7-d5-3-acetic Acid
|
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Indole-2,4,5,6,7-d5-3-acetic Acid 是 Indole-3-acetic Acid 的氘代化合物。Indole-3-acetic Acid 的 CAS 号为 87-51-4。3-Indoleacetic acid 是常见的天然植物生长激素。它可以诱导植物细胞的伸长和分裂。 | |||
TMIJ-0008 |
3-Amino-2-Oxazolidinone-d4
Aoz-d4 |
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3-Amino-2-Oxazolidinone-d4 是 3-Amino-2-Oxazolidinone 的氘代化合物。3-Amino-2-Oxazolidinone 的 CAS 号为 80-65-9。3-Amino-2-oxazolidinone 是一种呋喃唑烷酮的代谢物 (metabolite),可用作检测呋喃唑烷酮残留的一个指标。 | |||
TMIH-0028 |
2-(1-(methyl-d3)-1H-imidazol-4-yl)ethan-1-amine 2HCl
1-Methylhistamine-d3 Dihydrochloride |
||
2-(1-(methyl-d3)-1H-imidazol-4-yl)ethan-1-amine 2HCl 是 2-(1-(methyl)-1H-imidazol-4-yl)ethan-1-amine 2HCl 的氘代化合物。2-(1-(methyl)-1H-imidazol-4-yl)ethan-1-amine 2HCl 的 CAS 号为 6481-48-7。1-Methylhistamine dihydrochloride 是组胺代谢物。 | |||
TMIJ-0363 |
DL-Valine-d8
|
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DL-Valine-d8 是 DL-Valine 的氘代化合物。DL-Valine 的 CAS 号为 516-06-3。DL-Valine 是 2-氨基-3-甲基丁酸。它是在植物中从丙酮酸开始通过几个步骤合成的。 | |||
T35790 |
Palmitic acid-1,2,3,4-13C4
Palmitic Acid-13C (C1, C2, C3, and C4 labeled) |
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Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellula... |