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Targets Recommended: Adrenergic Receptor

224

抑制剂 & 化合物

57

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43

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Cat. No. Product Name Target Signaling Pathways
T6703 Tetrahydrozoline hydrochloride

Murine Plus,盐酸四氢萘咪唑,Tetryzoline hydrochloride,Tyzine,Tetrahydrozoline HCl,盐酸四氢唑林

Adrenergic Receptor GPCR/G Protein; Neuroscience
Tetrahydrozoline hydrochloride (Murine Plus) 是一种咪唑啉的衍生物,是一种 α-肾上腺素能 (α-adrenergic) 激动剂,能引起血管收缩,常用于研究鼻充血、结膜充血。
T79921 Moloney murine leukemia virus RT

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Moloney murine leukemia virus RT为源自Moloney小鼠白血病病毒的逆转录酶,作为复制聚合酶在逆转录病毒生命周期中扮演关键角色。
T38155 N-Acetyl-D-cysteine

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
N-Acetyl-D-cysteine 具有抗氧化活性,机制是通过与巯基反应清除ROS。N-Acetyl-D-cysteine 不能进入谷胱甘肽代谢途径。
T0120 Voriconazole

UK-109496,伏立康唑

Antifection; Antifungal Microbiology/Virology
Voriconazole (UK-109496) 是一种三唑类抗真菌剂,可抑制真菌麦角甾醇的生物合成。它特异性抑制由真菌细胞色素 P450 酶介导的 14-α-羊毛甾醇去甲基化作用
T12575 Unesbulin

PTC596

Apoptosis; BMI-1 Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Unesbulin (PTC596) 是一种口服有效和选择性的 B 细胞特异性莫洛尼氏鼠白血病病毒整合位点 1 抑制剂。它在急性髓细胞白血病细胞中可下调 MCL-1 并诱导不依赖 p53 的线粒体凋亡,具有抗白血病作用。
T1209 Flunixin meglumine

Banamine,Finadyne,Flunixin meglumin,氟尼辛葡甲胺

COX Immunology/Inflammation; Neuroscience
Flunixin meglumine (Banamine) 是一种环氧合酶抑制剂,具有抗炎和解热活性。
T19794 Temafloxacin

替马沙星,Omniflox

Antibiotic Microbiology/Virology
Temafloxacin (Omniflox) 是一种喹诺酮类广谱抗菌剂,对革兰氏阳性菌、革兰氏阴性菌和厌氧菌均有效。
T12684 Radioprotectin-1

5-chloro-2-[4-(1,3-dioxobenzo[de]isoquinolin-2-yl)butylsulfamoyl]benzoic acid

LPA Receptor GPCR/G Protein
Radioprotectin-1 是特异性的 LPA2 激动剂,对小鼠 LPA2 GPCR 的 EC50 为 25 nM,具有辐射保护和辐射缓解作用。
T17103 TM-N1324

Others; GHSR GPCR/G Protein; Others
TM-N1324 是一种 GPR39 激动剂。 TM-N1324 在没有和存在 Zn2+ 的情况下分别以 280 nM 和 9 nM 的高效率和效力激活人 GPR39。 TM-N1324 对鼠 GPR39 表现出相似的效力,EC50 分别为 180 nM 和 5 nM。
T22893 L-168049

L-168,049

Glucagon Receptor GPCR/G Protein
L-168049 是一种选择性和非竞争性人胰高血糖素受体拮抗剂,对人、鼠和犬的 IC50 分别为 3.7 nM、63 nM 和 60 nM。
T38514 PMEDAP

Others; HIV Protease Microbiology/Virology; Others; Proteases/Proteasome
PMEDAP 是有效的人类免疫缺陷病毒 (HIV) 复制抑制剂。它具有抗小鼠巨细胞病毒活性。它有效抑制莫罗尼鼠肉瘤病毒诱导的肿瘤形成和相关死亡率。
T78337 Mouse IgG2a kappa, Isotype Control

Mouse IgG2a kappa, Isotype Control 是鼠源IIgG2a kappa 抗体的同型抗体。
T14924 Cenerimod

ACT-334441

S1P Receptor GPCR/G Protein
Cenerimod (ACT-334441) 是一种具有口服活性、选择性和高效性的磷酸鞘氨醇 1 受体(S1P1)激动剂(EC50:1 nM)。Cenerimod 对多种 S1P 的亚型具有抑制作用,可用于研究鼠类实验性自身免疫性脑脊髓炎 (EAE)和鼠类硬皮病。
T1792L Regorafenib monohydrate

Raf; VEGFR; c-RET; PDGFR; c-Kit; Autophagy Angiogenesis; Apoptosis; Autophagy; MAPK; Tyrosine Kinase/Adaptors
Regorafenib monohydrate 是一种新型口服多激酶抑制剂,对VEGFR1/2/3、PDGFRβ、Kit、RET 和Raf-1的IC50分别为 13、4.2、46、22、7、1.5 和 2.5 nM。
T40380 17α-Hydroxyprogesterone acetate

Others Others
17α-Hydroxyprogesterone acetate 具有孕激素活性和抗炎活性。
T7506 Yoda 1

Piezo Channel Membrane transporter/Ion channel
Yoda 1 是Piezo1激动剂,能够激活纯化的 Piezo1 通道。
T9588 JI130

Others Others
JI130 能够削弱 Hes1 抑制转录的能力。 JI130 治疗显著减少了小鼠胰腺肿瘤异种移植模型中的肿瘤体积。
T10397 ATN-161 trifluoroacetate salt

ATN-161 TFA salt

Integrin Cytoskeletal Signaling
ATN-161 trifluoroacetate salt (ATN-161 TFA salt) 是一种新型整合素 α5β1 拮抗剂,可在小鼠模型中抑制血管生成和肝转移瘤的生长。
T10133 3'-Azido-3'-deoxy-5-methylcytidine

Antiviral; HIV Protease Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
3'-Azido-3'-deoxy-5-methylcytidine 抑制 HIV-1 逆转录酶 (EC50 = 0.06 μM),是异嗜性鼠白血病相关逆转录病毒 (XMRV, CC50 = 43.5 μM) 的有效抑制剂。
T24706 RBC10

RBC 10,RBC-10

GTPase GPCR/G Protein
RBC10 抑制 Ral 与其效应物 RALBP1 的结合,以及抑制 Ral 介导的鼠胚胎成纤维细胞的细胞扩散和人类癌细胞系的非贴壁依赖性生长。
TQ0156 GW1929

PPAR DNA Damage/DNA Repair; Metabolism
GW1929是PPAR-γ有效激动剂,对人PPAR-γ的pKi 为8.84。对人和鼠的pEC50分别为8.56 和 8.27。
T9411 KX2-361

Others; Microtubule Associated; Src Angiogenesis; Cytoskeletal Signaling; Others; Tyrosine Kinase/Adaptors
KX2-361 是一种口服生物可利用的小分子双 Src/微管蛋白抑制剂,可在小鼠胶质母细胞瘤模型中提供长期存活。
T7183 CPI-444

V81444,ciforadenant

Adenosine Receptor GPCR/G Protein; Neuroscience
CPI-444 (V81444) 是一种选择性的,可口服的 A2A 受体 (A2AR) 拮抗剂,可诱导抗肿瘤反应。
T3589 NSC23005 Sodium

CDK Cell Cycle/Checkpoint
NSC23005 sodium 是新型 p18 抑制剂 (ED50=5.21 nM),在小鼠和人类模型中促进造血干细胞扩增。
T5341 WYC-209

WYC209

Apoptosis; Retinoid Receptor; Autophagy Apoptosis; Autophagy; Metabolism
WYC-209 是一种合成类视黄醇,是维甲酸受体激动剂。它主要通过 caspase 3途径抑制恶性鼠黑色素瘤肿瘤再生细胞的增殖,IC50值为 0.19 μM。
TP1600L Iα52 acetate(137756-45-7 free base)

Others Others
Iα52 acetate(137756-45-7 free base) 是一种天然加工的肽,包含鼠 I-Eα 链的 52-68 位残基,可能有助于选择未成熟的 T 细胞。
T67936 BAY-0069

PPAR DNA Damage/DNA Repair; Metabolism
BAY-0069 是一种 PPARγ 反向激活剂,具有有效性和选择性,对人 PPARγ 和鼠 PPARγ 具有抑制作用, IC50 分别为 6.3 nM 和 24 nM。BAY-0069 可用于研究癌症。
T77408 Abagovomab

ACA 125

Others Others
Abagovomab (Anti-Human CA-125 Recombinant Antibody) 是一种独特型靶向肿瘤相关抗原 CA-125 的鼠源单克隆抗体。Abagovomab 由小鼠杂交瘤细胞产生。Abagovomab 可用于研究卵巢癌。
T3502 C29

TLR Immunology/Inflammation
C29 是 Toll 样受体 2 抑制剂,可阻断 hTLR2/1 和 hTLR2/6 信号,IC50值分别为 19.7 和 37.6 μM。
T17018 TCPOBOP

BCL Apoptosis
TCPOBOP 是一种组成型雄烷受体激动剂,可诱导强大的肝细胞增殖和肝肿大。它通过改变 Bcl-2 蛋白来减少 Fas 诱导的小鼠肝损伤。
T21578 NSC 66811

Mdm2 Apoptosis
NSC 66811 是一种MDM2-p53抑制剂,其结合到 MDM2 的Ki 值为 120 nM。
T78268 Anti-Mouse NK1.1 Antibody (PK136)

Anti-Mouse NK1.1 Antibody (PK136) 是鼠源靶向 NK1.1的IgG2a类抗体,可消除外周血、脾脏和肺组织中的NK1.1和NK1.1NKT细胞,抑制 NK1.1 信号传导,可用于研究心肺衰竭。
T3080 Pyridone 6

Janus-Associated Kinase Inhibitor I,JAK Inhibitor,CMP 6,吡啶酮6,JAK Inhibitor I

Tyrosine Kinases; JAK Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
Pyridone 6 (JAK Inhibitor) 是一种泛JAK 抑制剂,有效抑制 JAK 激酶家族,对JAK2、TYK2、JAK3和JAK1的IC50分别为 1、1、5 和 15 nM。
T11090L1 Aldoxorubicin hydrochloride

Aldoxorubicin hydrochloride (1361644-26-9 Free base)

Topoisomerase; ADC Cytotoxin Antibody-drug Conjugate/ADC Related; DNA Damage/DNA Repair
Aldoxorubicin hydrochloride 是 Doxorubicin (DNA 拓扑异构酶 II 抑制剂) 的白蛋白结合前药。Aldoxorubicin hydrochloride 在酸性条件下从白蛋白中释放出来。 Aldoxorubicin hydrochloride 显示出有效的抗肿瘤活性。
T78308 Tenatumomab

ST2146

Tenatumomab (ST2146) 是一种针对过度表达于癌症中的大型细胞外糖蛋白tenascin-C 的鼠源单克隆抗体。它已被应用于预靶向抗体引导放射免疫研究(PAGRIT),用以携带放射性同位素131碘,直接或通过PAGRIT技术向肿瘤细胞进行靶向放疗。
T6273 Vadimezan

DMXAA,伐地美生,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404

Influenza Virus; VDA; STING; IFNAR Angiogenesis; Immunology/Inflammation; Microbiology/Virology
Vadimezan (DMXAA) 是一种血管破坏剂,一种鼠 STING 激动剂,也是一种细胞因子如 I 型 IFN 的诱导剂。Vadimezan 具有抗肿瘤活性,可以诱导肿瘤中的血流快速停止,但不影响正常组织中的血流。
T8695 5-Hydroxymethyldeoxyuridine

Others Others
5-Hydroxymethyldeoxyuridine 是一种核苷类似物,具有抗癌和抗病毒活性。它抑制鼠 S180 肺癌细胞和 Ehrlich 腹水乳腺癌细胞(ED50s = 8.5 和 4 μM,分别)和多种人类白血病细胞系(IC50s = 1.7-5.8 μM)的复制。
T3486 3-MATIDA

GluR; NMDAR Neuroscience
3-MATIDA 是一种有效的 mGluR-1 拮抗剂(IC50:6.3 μM,大鼠 mGluR-1a)。显示出 ≥ 40 倍于其他受体的选择性:mGluR-5、mGluR-2、mGluR-4 (mGluR-4a) (IC50 > 300 μM)、NMDA 和 GluR (AMPA) (IC50 = 250 μM)。 3-MATIDA 在体外培养的鼠皮质细胞和大鼠海马切片培养物中充当神经保护剂。
T10831L Cl-amidine hydrochloride

Apoptosis; PAD Apoptosis; Chromatin/Epigenetic
Cl-amidine hydrochloride 是一种口服有效的PAD 抑制剂,可阻断组蛋白 3 瓜氨酸化和中性粒细胞胞外陷阱的形成,并提高败血症小鼠的存活率。它可诱导癌细胞凋亡,还可诱导 miR-16 引起细胞周期阻滞。
T6695 Tasquinimod

他喹莫德,ABR-215050

HDAC Chromatin/Epigenetic; DNA Damage/DNA Repair
Tasquinimod (ABR-215050) 是一种口服抗血管生成剂,有潜在的抗肿瘤活性。它也是 S100A9抑制剂,与 HDAC4Zn2+结合结构域结合的 Kd 值在10到30 nM 之间。
T3627 IQ-1S free acid

IQ-1,IQ-1S,IQ-1S (free acid)

NF-κB; JNK MAPK; NF-κB
IQ-1S free acid (IQ-1S) 是 NF-κB/激活蛋白1 (AP-1) 抑制剂(IC50:2.3±0.41 μM)。它对 JNK1(Kd:240 nM)、JNK2(Kd:360 nM) 和 JNK3(Kd:100 nM)的都具有高的结合亲和力 。
T24816 SP-100030

SP100030,SP 100030

NF-κB NF-κB
SP-100030 是一种有效的 NF-κB 和激活蛋白-1 (AP-1) 双抑制剂 (IC50 分别为 50 和 50 nM)。SP-10003 抑制 Jurkat 和其他T 细胞系产生的 IL-2、IL-8 和 TNF-α 的产生。SP-100030 降低小鼠胶原性关节炎 (CIA)。
T1298 Clofibrate

氯贝丁酯,氯贝特,Clofibrato,Clofibratum,Ethyl clofibrate

PPAR DNA Damage/DNA Repair; Metabolism
Clofibrate (Clofibrato) 是芳氧基异丁酸衍生物,具有抗高血脂活性。它是一种 PPAR 的激动剂,对人和鼠 PPARα 和 PPARγ 的 EC50值分别为 55 μM,约500 μM 和 50 μM,约500 μM。
T23027 MRT-10

Hedgehog/Smoothened GPCR/G Protein; Stem Cells
MRT 10 是一种七跨膜平滑受体 (Smo) 拮抗剂,通过多种 Hedgehog (Hh) 测定,其IC50=0.65 μM。它与Smo 受体结合的位点是 Bodipycyclopamine。它可用于研究癌症。
T0841 Bezafibrate

BM15075,苯扎贝特

PPAR DNA Damage/DNA Repair; Metabolism
Bezafibrate (BM15075) 是一种降血脂剂,是PPAR 的激动剂,对人以及鼠PPARα、PPARγ和PPARδ的EC50分别为 50、60和20 μM, 以及 90、55 和110 μM。
T3170 Troglitazone

CS-045,Romozin,Rezulin,Romglizone,Noscal,Prelay,曲格列酮

Apoptosis; Ferroptosis; PPAR; Autophagy Apoptosis; Autophagy; DNA Damage/DNA Repair; Metabolism
Troglitazone (Romglizone) 是一种 PPARγ 激动剂,具有口服活性。Troglitazone 具有降血糖活性,可以改善胰岛素抵抗,增强胰岛素作用。Troglitazone 还具有抗炎和抗肿瘤活性。
T10474 BAY-7598

Others Others
BAY-7598 is a potent, selective, and orally bioavailable MMP12 inhibitor (IC50s: 0.085, 0.67, and 1.1 nM for human/murine/rat MMP12).
T20338 Methopterin

NSC 107144,alpha-Methopterin,NSC-107144,10-Methylfolic acid,NSC107144

Others Others
Methopterin shows the activation and bone resorption function of murine osteoclasts.
T69320 Aminoquinuride

Others Others
Aminoquinuride, also known as Surfen, is a proteoglycan binding agent that reduces inflammation but inhibits remyelination in murine models of Multiple Sclerosis. Murine T cell activation is regulated by Surfen.
T34694 Spicamycin

Others Others
Spicamycin can be used as a potent inducer of differentiation of human myeloid leukemia cells (HL-60) and murine myeloid leukemia cells (M1).

化合物

Tetrahydrozoline hydrochloride
Cat.No: T6703
Synonym: Murine Plus,盐酸四氢萘咪唑,Tetryzoline hydrochloride,Tyzine,Tetrahydrozoline HCl,盐酸四氢唑林
Target: Adrenergic Receptor
Moloney murine leukemia virus RT
Cat.No: T79921
Synonym:
Target: DNA/RNA Synthesis
N-Acetyl-D-cysteine
Cat.No: T38155
Synonym:
Target: Reactive Oxygen Species
Voriconazole
Cat.No: T0120
Synonym: UK-109496,伏立康唑
Target: Antifection, Antifungal
Unesbulin
Cat.No: T12575
Synonym: PTC596
Target: Apoptosis, BMI-1
Flunixin meglumine
Cat.No: T1209
Synonym: Banamine,Finadyne,Flunixin meglumin,氟尼辛葡甲胺
Target: COX
Temafloxacin
Cat.No: T19794
Synonym: 替马沙星,Omniflox
Target: Antibiotic
Radioprotectin-1
Cat.No: T12684
Synonym: 5-chloro-2-[4-(1,3-dioxobenzo[de]isoquinolin-2-yl)butylsulfamoyl]benzoic acid
Target: LPA Receptor
TM-N1324
Cat.No: T17103
Synonym:
Target: Others, GHSR
L-168049
Cat.No: T22893
Synonym: L-168,049
Target: Glucagon Receptor
PMEDAP
Cat.No: T38514
Synonym:
Target: Others, HIV Protease
Mouse IgG2a kappa, Isotype Control
Cat.No: T78337
Synonym:
Target:
Cenerimod
Cat.No: T14924
Synonym: ACT-334441
Target: S1P Receptor
Regorafenib monohydrate
Cat.No: T1792L
Synonym:
Target: Raf, VEGFR, c-RET, PDGFR, c-Kit, Autophagy
17α-Hydroxyprogesterone acetate
Cat.No: T40380
Synonym:
Target: Others
Yoda 1
Cat.No: T7506
Synonym:
Target: Piezo Channel
JI130
Cat.No: T9588
Synonym:
Target: Others
ATN-161 trifluoroacetate salt
Cat.No: T10397
Synonym: ATN-161 TFA salt
Target: Integrin
3'-Azido-3'-deoxy-5-methylcytidine
Cat.No: T10133
Synonym:
Target: Antiviral, HIV Protease
RBC10
Cat.No: T24706
Synonym: RBC 10,RBC-10
Target: GTPase
GW1929
Cat.No: TQ0156
Synonym:
Target: PPAR
KX2-361
Cat.No: T9411
Synonym:
Target: Others, Microtubule Associated, Src
CPI-444
Cat.No: T7183
Synonym: V81444,ciforadenant
Target: Adenosine Receptor
NSC23005 Sodium
Cat.No: T3589
Synonym:
Target: CDK
WYC-209
Cat.No: T5341
Synonym: WYC209
Target: Apoptosis, Retinoid Receptor, Autophagy
Iα52 acetate(137756-45-7 free base)
Cat.No: TP1600L
Synonym:
Target: Others
BAY-0069
Cat.No: T67936
Synonym:
Target: PPAR
Abagovomab
Cat.No: T77408
Synonym: ACA 125
Target: Others
C29
Cat.No: T3502
Synonym:
Target: TLR
TCPOBOP
Cat.No: T17018
Synonym:
Target: BCL
NSC 66811
Cat.No: T21578
Synonym:
Target: Mdm2
Anti-Mouse NK1.1 Antibody (PK136)
Cat.No: T78268
Synonym:
Target:
Pyridone 6
Cat.No: T3080
Synonym: Janus-Associated Kinase Inhibitor I,JAK Inhibitor,CMP 6,吡啶酮6,JAK Inhibitor I
Target: Tyrosine Kinases, JAK
Aldoxorubicin hydrochloride
Cat.No: T11090L1
Synonym: Aldoxorubicin hydrochloride (1361644-26-9 Free base)
Target: Topoisomerase, ADC Cytotoxin
Tenatumomab
Cat.No: T78308
Synonym: ST2146
Target:
Vadimezan
Cat.No: T6273
Synonym: DMXAA,伐地美生,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404
Target: Influenza Virus, VDA, STING, IFNAR
5-Hydroxymethyldeoxyuridine
Cat.No: T8695
Synonym:
Target: Others
3-MATIDA
Cat.No: T3486
Synonym:
Target: GluR, NMDAR
Cl-amidine hydrochloride
Cat.No: T10831L
Synonym:
Target: Apoptosis, PAD
Tasquinimod
Cat.No: T6695
Synonym: 他喹莫德,ABR-215050
Target: HDAC
IQ-1S free acid
Cat.No: T3627
Synonym: IQ-1,IQ-1S,IQ-1S (free acid)
Target: NF-κB, JNK
SP-100030
Cat.No: T24816
Synonym: SP100030,SP 100030
Target: NF-κB
Clofibrate
Cat.No: T1298
Synonym: 氯贝丁酯,氯贝特,Clofibrato,Clofibratum,Ethyl clofibrate
Target: PPAR
MRT-10
Cat.No: T23027
Synonym:
Target: Hedgehog/Smoothened
Bezafibrate
Cat.No: T0841
Synonym: BM15075,苯扎贝特
Target: PPAR
Troglitazone
Cat.No: T3170
Synonym: CS-045,Romozin,Rezulin,Romglizone,Noscal,Prelay,曲格列酮
Target: Apoptosis, Ferroptosis, PPAR, Autophagy
BAY-7598
Cat.No: T10474
Synonym:
Target: Others
Methopterin
Cat.No: T20338
Synonym: NSC 107144,alpha-Methopterin,NSC-107144,10-Methylfolic acid,NSC107144
Target: Others
Aminoquinuride
Cat.No: T69320
Synonym:
Target: Others
Spicamycin
Cat.No: T34694
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T6S1027 Tussilagone

Others Others
Tussilagone 是Tussilago farfara 的主要活性成分,具有抗炎作用。它抑制盲肠结扎和穿刺导致脓毒症的小鼠的炎症反应,提高其生存率。它改善葡聚糖硫酸钠诱导的小鼠结肠炎的炎症反应。
T37341 N-Acetyltyramine

Antibacterial Microbiology/Virology
N-Acetyltyramine 是一种群体感应抑制剂,由溶藻弧菌 M3-10 产生。N-Acetyltyramine 可以抑制C. violaceumATCC 12472 的群体感应。它可以逆转阿霉素耐药白血病 P388 细胞的耐药性。
T0934 Nicotinamide

Nicotinic acid amide,Vitamin B3,Niacinamide,烟酰胺,Vitamin PP

Sirtuin; Endogenous Metabolite Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
Nicotinamide 是维生素 B3 的吡啶核苷形式,可作为烟酰胺腺嘌呤二核苷酸或 NAD+ 的前体,可通过膳食摄入来补充,能预防或治疗黑舌病和糙皮病。
TN6369 Amurine

C09334

Antifungal Microbiology/Virology
Amurine (C09334) 是一种从P. stylatum分离出来的生物碱,具有潜在的抗菌活性。
T3829 Ginsenoside F3

人参皂苷F3

Others; IFNAR; Interleukin Immunology/Inflammation; Others
Ginsenoside F3 是一种皂苷,提取自Panax ginseng 叶片。它能够调节1 型 (IL-2, IFN-γ) 及 2 型细胞因子(IL-4 and IL-10) 的产生和表达,有免疫增强的作用。
T36115 Colchicoside

3-Demethylcolchicine glucoside

Others Others
Colchicoside (3-Demethylcolchicine glucoside) 提取自嘉兰,在胰腺癌小鼠模型中显示出疗效。
TN1697 Glucosyringic acid

葡萄糖基丁香酸

Immunology/Inflammation related Immunology/Inflammation
Glucosyringic acid 具有免疫抑制作用,在体外能抑制鼠 B 淋巴细胞的增殖。
T2978 Mogroside V

AMPK Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
Mogroside V 是三萜糖苷,是非糖类甜味剂,甜度比蔗糖甜高300倍。它具有抗氧化,抗糖尿病和抗癌作用。
T7052 Gnetol

Tyrosinase; COX; HDAC; AChR Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation; Neuroscience; Proteases/Proteasome
Gnetol 是从买麻藤的根中分离出来的一种酚类。它是酪氨酸酶抑制剂,对鼠酪氨酸酶的 IC50为 4.5 μM,可抑制黑色素的生物合成。它有效抑制 COX-1和 HDAC,具有抗氧化、抗增殖、抗癌和保肝活性,还具有浓度依赖性的 α-淀粉酶、α-葡萄糖苷酶和脂肪形成活性。
TN6339 (R)-5-Hydroxy-1,7-diphenylheptan-3-one

(5R)-Dihydroyashabushiketol,(R)-5-羟基-1,7-二苯基-3-庚酮

Others Others
(R)-5-Hydroxy-1,7-diphenylheptan-3-one ((5R)-Dihydroyashabushiketol) 是从中药材高良姜的根茎中提取的。它抑制茶碱刺激的鼠 B16 黑色素瘤 4A5 细胞中的黑色素生成。
T6S1543 Dehydrodiisoeugenol

去氢二异丁香酚,脱氢二异丁香酚

Others; NF-κB; COX; Antibacterial Immunology/Inflammation; Microbiology/Virology; Neuroscience; NF-κB; Others
Dehydrodiisoeugenol 是从Myristica fragrans Houtt 中分离得到的天然产物,具有抗炎和抗菌作用。它抑制 LPS 刺激的小鼠巨噬细胞中NF-κB 活化和环氧合酶 (COX)-2 基因的表达。
T3S0645 N-trans-Feruloyltyramine

Feruloyltyramine,N-Feruloyltyramine,Moupinamide,N-反式阿魏酰酪胺

Others; COX Immunology/Inflammation; Neuroscience; Others
N-trans-Feruloyltyramine (Feruloyltyramine) 是从大麻中分离得到的一种生物碱,是COX1和COX2的抑制剂,具有抗氧化和抗炎活性。
T3S0153 Xanthatin

苍耳亭,叶黄制菌素

Apoptosis; VEGFR; Lipoxygenase; Wnt/beta-catenin; Antibacterial Angiogenesis; Apoptosis; Cytoskeletal Signaling; Metabolism; Microbiology/Virology; Stem Cells; Tyrosine Kinase/Adaptors
Xanthatin 是一种从Xanthium strumarium 叶子中提取的天然产物,可诱导细胞凋亡。它抑制布鲁氏菌的IC50值为 2.63 μg/ mL,对寄生虫特异性锥虫硫磷还原酶具有不可逆的弱抑制作用。它通过抑制PGE2的合成和 5-脂氧合酶的活性而显示出抗炎活性。
T4S0350 Licochalcone B

甘草查尔酮 B,甘草查尔酮B

Beta Amyloid; Others Neuroscience; Others
Licochalcone B 是从Glycyrrhiza inflate 根中提取的。它能够抑制淀粉样蛋白 β 自聚集作用 (IC50=2.16 μM) ,分解预先形成的 Aβ42原纤维,并通过螯合金属离子抑制金属诱导的 Aβ42聚集。
T3S0737 Flavokawain A

2'-羟基-4,4',6'-三甲氧基查耳酮,Flavokavain A

Apoptosis; p38 MAPK Apoptosis; MAPK
Flavokawain A (Flavokavain A) 是 kava 提取物中的查耳酮,是一种抗癌试剂,具有抗肿瘤活性。它通过 Bax 蛋白依赖和线粒体依赖的凋亡途径诱导细胞凋亡,有潜力用于膀胱癌的相关研究。
TCS2170 2,5-Dihydroxyacetophenone

Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,2 ',5'-二羟基苯乙酮,Acetylhydroquinone,2,5-二羟基苯乙酮,DHAP

ERK; NF-κB; Tyrosinase MAPK; NF-κB; Proteases/Proteasome
2,5-Dihydroxyacetophenone (Quinacetophenone) 是从熟地黄中分离出的一种天然产物,通过阻断 ERK1/2和 NF-κB 信号通路,抑制活化巨噬细胞中炎症介质的产生。
T40790 ω-Muricholic Acid

Others Others
ω-Muricholic acid (ω-MCA) is a murine-specific secondary bile acid.
TN2029 p-Hydroxy-5,6-dehydrokawain

4'-Hydroxydehydrokawain,4'-羟基-5,6-脱氢醉椒素

Others Others
p-Hydroxy-5,6-dehydrokawain (4'-Hydroxydehydrokawain) 是一种分离自 Kawain 的天然产物。
TN6048 Zarzissine

Zarzissine exhibits cytotoxicity against three human and murine tumor cell lines.
TN5212 Uvedalin

Others Others
Uvedalin shows cytotoxicity against HeLa, HL-60, and Murine B16-F10 melanoma cell lines.
T72578 Siegesbeckialide I

Others Others
Siegesbeckialide I 在 RAW264.7 细胞中通过直接结合IKKα/β有效地抑制 LPS 诱导的 NO 生成。
TN1486 Chimonanthine

Others Others
(-)-Chimonanthine (IC50 = 0.93 μM) shows potent inhibitory effects on melanogenesis in theophylline-stimulated murine B16 melanoma 4A5 cells.
T68865 Amoorastatin

Others Others
Amoorastatin is a natural product that has been studied in cancer research. Its derivative was found to significantly inhibit growth of the murine P388 lymphocytic leukemia cell lines.
TN4047 Excisanin B

Others Others
Excisanin B shows inhibitory effects on LPS-induced production of nitric oxide in murine macrophage RAW264.7 cells.
TN1242 3,3'-Di-O-methylellagic acid

3,8-Di-O-methylellagic acid,3,3'-O-二甲基鞣花酸

Others; TNF; Antifection Apoptosis; Microbiology/Virology; Others
3,3'-Di-O-methylellagic acid reveals moderate antibacterial activity, it also shows strong DPPH radical scavenging activities with SC50 of 123.3 ug/mL. It has a lower capacity of stimulating murine peritoneal macrophages to release nitric oxide and tumoural-alpha necrose factor
TN4050 Fargesone A

NOS Immunology/Inflammation
Fargesone A shows inhibitory effects on nitric oxide (NO) production in the lipopolysaccharide plus interferon-gamma activated-murine macrophage cell line, J774.1.
TN2813 23-deoxojessic acid

Others Others
23-Deoxojessic acid possesses strong cytotoxicity towards highly liver metastatic murine colon 26-L5 carcinoma cells, with ED50 values equal to or less than 6 microM.
T72858 Maydispenoid B

Others Others
Maydispenoid B,一种有效的免疫抑制剂,能够抑制抗CD3/抗CD28单抗和脂多糖激活的小鼠脾细胞增殖。
T38338 Quinolactacin A

Others Others
Quinolactactin A is a quinolone fungal metabolite originally isolated from Penicillium. It inhibits TNF production induced by LPS in murine peritoneal macrophages (IC50 = 12.2 μg/ml). It is not active against a variety of bacteria, fungi, and yeasts. Quinolactacin A is a mixture of quinolactacin A1 and A2.
TN4089 Futokadsurin C

Others Others
Futokadsurin C can inhibit nitric oxide production by a murine macrophage-like cell line (RAW 264.7), which is activated by lipopolysaccharide and interferon-gamma.
T14317 ar-Turmerone

(+)-ar-Turmerone

Others Others
ar-Turmerone ((+)-ar-Turmerone) is a major bioactive compound of the herb Curcuma longa with anti-tumorigenesis and anti-inflammatory activities[1][2][3]. ar-Turmerone ((+)-ar-Turmerone) exerts positive modulation on murine DCs, induces NSC proliferation.
TN3461 Asebotin

Influenza Virus Microbiology/Virology
Asebotin shows anti-influenza A virus activity, it also possesses potent antiviral activity (100% inhibition at the concentration of 1 ug /mL) against highly pathogenic avian influenza strain H5N1. Asebotin can inhibit the proliferation of murine B cells.
T35400 β-Muricholic Acid

β-MCA,5β-Cholanic Acid-3α,6β,7β-triol,β-Muricholic Acid

Others Others
β-Muricholic acid (β-MCA) is a murine-specific primary bile acid.[1],[2] Dietary administration of β-MCA reduces HMG-CoA reductase activity in liver microsomes from mice fed a high cholesterol and cholic acid diet.[3] Dietary administration of β-MCA also dissolves 100% of gallstones in a gallstone-susceptible mouse model of diet-induced cholesterol gallstones.[4]
T72857 Maydispenoid A

Others Others
Maydispenoid A, 作为一种有效的免疫抑制剂,能够抑制抗CD3/抗CD28单抗和脂多糖激活的小鼠脾细胞增殖。
TN2106 Protodeltonin

原三角叶皂苷

BCL; PARP; Caspase Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome
Protodeltonin may have anti-thrombotic activity by both improving the anticoagulation activity and inhibiting platelet aggregation action. Protodeltonin can inhibit the proliferation of a panel of established human and murine cancer cell lines in vitro.
TN5233 Villosin

Others Others
Villosin exhibits potent cytotoxic activity , it may be used as a potential lead molecule for antitumor therapeutic development. Villosin shows inhibitory effects against nitric oxide production in LPS and IFN-γ-induced RAW 264.7 murine macrophages with I
TN3869 Dimeric coniferyl acetate

Others Others
Dimeric coniferyl acetate has anti-inflammary activity, it shows strong NO inhibition with IC50 values of 27.1 uM in lipopolysacchalide (LPS)-activated murine macrophage-like J774.1 cells. It exhibits significant inhibitory effects on the nitric oxide pro
TN4623 Nagilactone C

Antifection Microbiology/Virology
Nagilactone C and phyllanthoside are novel protein synthesis inhibitors, they are specific for the eukaryotic translation apparatus, function in vivo and in vitro, and interfere with translation elongation. Nagilactone C shows high insecticidal activity against second-instar nymphs of Eocanthecona furcellata. Nagilactone C possesses potent antiproliferative activity against human fibrosarcoma and murine colon carcinoma tumor cell lines exhibiting ED50 values of 2.3 and 1.2 microg/ml, respectivel...
T36931 Penicillide

Others Others
Penicillide is a fungal metabolite originally isolated from Penicillium that has diverse biological activities. It is an inhibitor of calpain 2/m-calpain (IC50 = 7.1 μM) and acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 22.9 μM). It is also an antagonist of oxytocin receptors (IC50 = 67 μM). Penicillide inhibits RNA synthesis in P388 murine leukemia cells.
T36337 Burnettramic Acid A aglycone

Others Others
Burnettramic acid A aglycone is a fungal metabolite and an aglycone form of burnettramic acid A originally isolated fromA. burnettiithat has anticancer activity.1It is cytotoxic to NS-1 murine myeloma cells but not neonatal foreskin fibroblasts (IC50s = 8.4 and >100 μg/ml, respectively). 1.Li, H., Gilchrist, C.L.M., Lacey, H.J., et al.Discovery and heterologous biosynthesis of the burnettramic acids: Rare PKS-NRPS-derived bolaamphiphilic pyrrolizidinediones from an Australian fungus, Aspergillus...
TN4146 Glutinol acetate

TNF Apoptosis
Glutinol acetate shows significant cytotoxic activity against four human cancer cell lines (HL-60, SK-OV-3, A549, and HT-29), with GI(50) in the range of 11.1-17.9microM; it also has anti-inflammatory effect, exhibits moderate inhibitory activity of TNF-alpha secretion in the lipopolysaccharide (LPS)-stimulated murine RAW264.7 macrophage cell line.
TN4263 Isoangustone A

MMP; GSK-3; NF-κB; ROS; Akt; PI3K; CDK; JNK Cell Cycle/Checkpoint; Cytoskeletal Signaling; Immunology/Inflammation; MAPK; NF-κB; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation by targeting PI3K, MKK4, and MKK7 in human melanoma. Isoangustone A dampens mesangial sclerosis associated with inflammation in response to high glucose through hindering TGF-β and NF-κB signaling. Isoangustone A also shows strong ferric reducing activities and effectively scavenged DPPH, ABTS(+), and singlet oxygen radicals.
TN3979 Epiyangambin

PAFR GPCR/G Protein
Epiyangambin is a phytotoxic lignan, it shows inhibition of seed germination of Agrostis stolonifera cv. penncross (Poaceae) and inhibition of development of Lactuca sativa L. (Asteraceae) seedlings in a microassay using 24-well plates. Epiyangambin exhibits significant inhibition of the transformation of murine epidermal JB6 cells, with the IC50 value of 0.15 microg/mL. (+)-Epiyangambin also has anti-platelet aggregation activity.
T38097 Antibiotic PF 1052

Others Others
Antibiotic PF 1052 is a fungal metabolite originally isolated from Phoma.1,2 It is active against S. aureus, S. parvulus, and C. perfringens (MICs = 3.13, 0.78, and 0.39 μg/ml, respectively), among others.1 It inhibits neutrophil migration in a wound assay using zebrafish larvae expressing GFP-labeled neutrophils, reducing pseudopodia formation and inducing rounding of neutrophils.2 Antibiotic PF 1052 is selective for neutrophil migration over macrophage migration in zebrafish larvae. It also in...
T75453 11-epi-Chaetomugilin I

Others Others
11-epi-Chaetomugilin I 是一种在Chaetomium globosum 中发现的代谢物。11-epi-Chaetomugilin I 对小鼠 P388 白血病细胞系、人类 HL-60 白血病细胞系、小鼠 L1210 白血病细胞系和人类 KB 表皮样癌细胞系具有显著的细胞毒性活性。
TN6062 1,3,9-Trimethyluric acid

1,3,9-Trimethyluric acid exhibits in vitro cytotoxic activity against breast cancer (MCF-7), human neuroblastoma (SHSY5Y), human non-small cell lung cancer (A549) and human liver cancer (HEPG2) with IC50 value in the range of 1-3 uM. 1,3,9-Trimethyluric a
T75890 Conantokin G TFA

Others Others
Conantokin G TFA 是一种 17 个氨基酸的肽,是一种有效,选择性和竞争性的 N-甲基-D-天冬氨酸 (NMDA) 受体拮抗剂。Conantokin G TFA 抑制鼠皮质神经元中NMDA 诱发的电流,IC50为 480 nM,具有神经保护作用。
TN7283 Lentztrehalose A

(+)-Lentztrehalose A

Others Others
Lentztrehalose A, a disaccharide microbial metabolite identified in Lentzea, exhibits a range of biological activities. This compound specifically inhibits M. smegmatis trehalase—an enzyme involved in trehalose metabolism—more effectively than trehalase from porcine kidney, with IC50 values of 0.67 mM and >20 mM, respectively. Additionally, Lentztrehalose A at a concentration of 100 mM promotes autophagy in MeWo melanoma and OVK18 ovarian cancer cells. When administered at 50 mg/kg daily, it enh...
T5157 9,13-Epidioxy-8(14)-abieten-18-oic acid

Others Others
9,13β-Epidioxy-8(14)-abieten-18-oic acid has anti-inflammatory activities, it exhibits moderate activities on NO levels in LPS-stimulated murine microglia BV2 cells, with IC50 values of 57.3 ± 0.2 uM. It is also a potential antitumor-promoting diterpenoid, it shows potent inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate. 9 α ,13 β -Epidioxyabeit-8(14)en-18-oic acid may contribute to the growth inhibitory...
TN2641 15-Methoxypinusolidic acid

ERK; IL Receptor; p38 MAPK; Calcium Channel; NOS; NF-κB; COX; JNK; NMDAR; PPAR DNA Damage/DNA Repair; Immunology/Inflammation; MAPK; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB
15-Methoxypinusolidic acid has anti-inflammatory effects, it inhibits LPS-induced iNOS expression and NO production, independent on MAPK and NF-kappaB. 15-Methoxypinusolidic acid suppresses adipocyte differentiation through the inhibition of PPARgamma-dep
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天然产物

Tussilagone
Cat.No: T6S1027
Synonym:
Target: Others
N-Acetyltyramine
Cat.No: T37341
Synonym:
Target: Antibacterial
Nicotinamide
Cat.No: T0934
Synonym: Nicotinic acid amide,Vitamin B3,Niacinamide,烟酰胺,Vitamin PP
Target: Sirtuin, Endogenous Metabolite
Amurine
Cat.No: TN6369
Synonym: C09334
Target: Antifungal
Ginsenoside F3
Cat.No: T3829
Synonym: 人参皂苷F3
Target: Others, IFNAR, Interleukin
Colchicoside
Cat.No: T36115
Synonym: 3-Demethylcolchicine glucoside
Target: Others
Glucosyringic acid
Cat.No: TN1697
Synonym: 葡萄糖基丁香酸
Target: Immunology/Inflammation related
Mogroside V
Cat.No: T2978
Synonym:
Target: AMPK
Gnetol
Cat.No: T7052
Synonym:
Target: Tyrosinase, COX, HDAC, AChR
(R)-5-Hydroxy-1,7-diphenylheptan-3-one
Cat.No: TN6339
Synonym: (5R)-Dihydroyashabushiketol,(R)-5-羟基-1,7-二苯基-3-庚酮
Target: Others
Dehydrodiisoeugenol
Cat.No: T6S1543
Synonym: 去氢二异丁香酚,脱氢二异丁香酚
Target: Others, NF-κB, COX, Antibacterial
N-trans-Feruloyltyramine
Cat.No: T3S0645
Synonym: Feruloyltyramine,N-Feruloyltyramine,Moupinamide,N-反式阿魏酰酪胺
Target: Others, COX
Xanthatin
Cat.No: T3S0153
Synonym: 苍耳亭,叶黄制菌素
Target: Apoptosis, VEGFR, Lipoxygenase, Wnt/beta-catenin, Antibacterial
Licochalcone B
Cat.No: T4S0350
Synonym: 甘草查尔酮 B,甘草查尔酮B
Target: Beta Amyloid, Others
Flavokawain A
Cat.No: T3S0737
Synonym: 2'-羟基-4,4',6'-三甲氧基查耳酮,Flavokavain A
Target: Apoptosis, p38 MAPK
2,5-Dihydroxyacetophenone
Cat.No: TCS2170
Synonym: Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,2 ',5'-二羟基苯乙酮,Acetylhydroquinone,2,5-二羟基苯乙酮,DHAP
Target: ERK, NF-κB, Tyrosinase
ω-Muricholic Acid
Cat.No: T40790
Synonym:
Target: Others
p-Hydroxy-5,6-dehydrokawain
Cat.No: TN2029
Synonym: 4'-Hydroxydehydrokawain,4'-羟基-5,6-脱氢醉椒素
Target: Others
Zarzissine
Cat.No: TN6048
Synonym:
Target:
Uvedalin
Cat.No: TN5212
Synonym:
Target: Others
Siegesbeckialide I
Cat.No: T72578
Synonym:
Target: Others
Chimonanthine
Cat.No: TN1486
Synonym:
Target: Others
Amoorastatin
Cat.No: T68865
Synonym:
Target: Others
Excisanin B
Cat.No: TN4047
Synonym:
Target: Others
3,3'-Di-O-methylellagic acid
Cat.No: TN1242
Synonym: 3,8-Di-O-methylellagic acid,3,3'-O-二甲基鞣花酸
Target: Others, TNF, Antifection
Fargesone A
Cat.No: TN4050
Synonym:
Target: NOS
23-deoxojessic acid
Cat.No: TN2813
Synonym:
Target: Others
Maydispenoid B
Cat.No: T72858
Synonym:
Target: Others
Quinolactacin A
Cat.No: T38338
Synonym:
Target: Others
Futokadsurin C
Cat.No: TN4089
Synonym:
Target: Others
ar-Turmerone
Cat.No: T14317
Synonym: (+)-ar-Turmerone
Target: Others
Asebotin
Cat.No: TN3461
Synonym:
Target: Influenza Virus
β-Muricholic Acid
Cat.No: T35400
Synonym: β-MCA,5β-Cholanic Acid-3α,6β,7β-triol,β-Muricholic Acid
Target: Others
Maydispenoid A
Cat.No: T72857
Synonym:
Target: Others
Protodeltonin
Cat.No: TN2106
Synonym: 原三角叶皂苷
Target: BCL, PARP, Caspase
Villosin
Cat.No: TN5233
Synonym:
Target: Others
Dimeric coniferyl acetate
Cat.No: TN3869
Synonym:
Target: Others
Nagilactone C
Cat.No: TN4623
Synonym:
Target: Antifection
Penicillide
Cat.No: T36931
Synonym:
Target: Others
Burnettramic Acid A aglycone
Cat.No: T36337
Synonym:
Target: Others
Glutinol acetate
Cat.No: TN4146
Synonym:
Target: TNF
Isoangustone A
Cat.No: TN4263
Synonym:
Target: MMP, GSK-3, NF-κB, ROS, Akt, PI3K, CDK, JNK
Epiyangambin
Cat.No: TN3979
Synonym:
Target: PAFR
Antibiotic PF 1052
Cat.No: T38097
Synonym:
Target: Others
11-epi-Chaetomugilin I
Cat.No: T75453
Synonym:
Target: Others
1,3,9-Trimethyluric acid
Cat.No: TN6062
Synonym:
Target:
Conantokin G TFA
Cat.No: T75890
Synonym:
Target: Others
Lentztrehalose A
Cat.No: TN7283
Synonym: (+)-Lentztrehalose A
Target: Others
9,13-Epidioxy-8(14)-abieten-18-oic acid
Cat.No: T5157
Synonym:
Target: Others
15-Methoxypinusolidic acid
Cat.No: TN2641
Synonym:
Target: ERK, IL Receptor, p38 MAPK, Calcium Channel, NOS, NF-κB, COX, JNK, NMDAR, PPAR
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Cat. No. Product Name Species Expression System
TMPJ-00135 BDNF Protein, Human/Murine/Rat, Recombinant

BDNF,Abrineurin,Brain-Derived Neurotrophic Factor

Human,Mouse,Rat E. coli
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. ...
TMPY-04552 AKT1 Protein, Human, Recombinant (His)

RAC-ALPHA,v-akt murine thymoma viral oncogene homol...

Human Baculovirus Insect Cells
v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to insulin, insulin-like growth factor 1 (IGF1), and glucose. AKT1 also plays a key role in the regulation of both muscle cell hypertrophy and atrophy. AKT1 activity is required for physiologic cardiac growth in response to IGF1 stimulation or exercise training. In contrast, AKT1 ac...
TMPY-04574 AKT3 Protein, Mouse, Recombinant (aa 106-479, His & GST)

v-akt murine thymoma viral oncogene homolog 3,Nmf35...

Mouse Baculovirus Insect Cells
AKT3 Protein, Mouse, Recombinant (aa 106-479, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 71 kDa and the accession number is Q9WUA6-1.
TMPY-04446 AKT3 Protein, Mouse, Recombinant (aa 106-479)

D930002M15Rik,AI851531,Nmf350,v-akt murine thymoma ...

Mouse Baculovirus Insect Cells
AKT3 Protein, Mouse, Recombinant (aa 106-479) is expressed in Baculovirus insect cells. The predicted molecular weight is 43.4 kDa and the accession number is Q9WUA6-1.
TMPH-02986 Murine polyomavirus (MPyV) (strain Kilham) VP2 Protein (His)

Minor capsid protein VP2,Minor structural protein VP2

MPyV E. coli
Murine polyomavirus (MPyV) (strain Kilham) VP2 Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 41.4 kDa and the accession number is P24596.
TMPY-04387 AKT2 Protein, Human, Recombinant (His & GST)

RAC-β,RAC-BETA,HIHGHH,PKBBETA,PKBβ,PRKBB,PKBB,v-akt muri...

Human Baculovirus Insect Cells
AKT (AK mouse plus Transforming or Thymoma) is a frequent oncogene expressed in most tissues which includes three isoforms AKT1, AKT2, and AKT3. Hyperactivation of AKT signaling is a central key in many human cancer progressions, through modulating angiogenesis, tumor growth, and cell migration, invasion, metastasis, and chemoresistance. Among all three isoforms, AKT2 is most related to cancer cell invasion, metastasis, and survival. Amplification and overexpression of AKT2 have been shown in ma...
TMPH-02984 Murine polyomavirus (MPyV) (strain Kilham) VP1 Protein (His)

Major structural protein VP1,Major capsid protein VP1

MPyV Baculovirus Insect Cells
Murine polyomavirus (MPyV) (strain Kilham) VP1 Protein (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 42.5 kDa and the accession number is P24595.
TMPH-02465 Moloney murine leukemia virus (MoMLV) (isolate Shinnick) Gag polyprotein (GST)

gag,Gag polyprotein,Core polyprotein

MoMLV E. coli
Moloney murine leukemia virus (MoMLV) (isolate Shinnick) Gag polyprotein (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 57.6 kDa and the accession number is P03332.
TMPH-02985 Murine polyomavirus (MPyV) (strain Kilham) VP1 Protein (E. coli, His)

Major structural protein VP1,Major capsid protein VP1

MPyV E. coli
Murine polyomavirus (MPyV) (strain Kilham) VP1 Protein (E. coli, His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 42.4 kDa and the accession number is P24595.
TMPY-04553 AKT3 Protein, Human, Recombinant (GST)

PRKBG,RAC-γ,RAC-PK-γ,MPPH,PKB-γ,PKBG,RAC-PK-gamma,STK-2,PKB-...

Human Baculovirus Insect Cells
AKT3 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 81 kDa and the accession number is Q9Y243-1.
TMPK-01414 Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein, Mouse, MHC (His & Avi)

Qa-1b,Qdm,MHC,H2-T23

Mouse HEK293 Cells
Qa-1b binds a peptide (AMAPRTLLL), referred to as Qdm (for Qa-1 determinant modifier), derived from the signal sequence of murine class Ia molecules. This peptide binds with high affinity and accounts for almost all of the peptides associated with this molecule. Human histocompatibility leukocyte antigen (HLA)-E, a homologue of Qa-1b, binds similar peptides derived from human class Ia molecules and interacts with CD94/NKG2 receptors on natural killer cells.
TMPY-01648 TREML2 Protein, Human, Recombinant (His)

TLT2,dJ238O23.1,triggering receptor expressed on myeloid cel...

Human HEK293 Cells
Trem-like transcript 2 protein, also known as Triggering receptor expressed on myeloid cells-like protein 2, TREML2 and TLT2, is a single-pass type I membrane protein that contains one Ig-like V-type (immunoglobulin-like) domain. TREML2 is detected in cultured B cells, T cell leukemia and monocyte leukemia. TREML2 is expressed constitutively on CD8 T-cells and induced on CD4 T-cells after activation. TREML2 is a cell surface receptor that may play a role in the innate and adaptive immune respons...
TMPK-00471 PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated

MGC2463,MGC104322,LPD,C7orf15,ALS2CR18,PREL2,ALS2CR9,RMO1,PR...

Mouse HEK293 Cells
Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth. PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 42.7 kDa and the accession number is ...
TMPK-00470 PVRIG Protein, Mouse, Recombinant (hFc & Avi)

PREL-2,RMO1,MGC2463,C7orf15,MGC104322,PREL2,PVRIG,LPD,MGC138...

Mouse HEK293 Cells
Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth. PVRIG Protein, Mouse, Recombinant (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 42.70 kDa and the accession number is A0A1B0GS01.
TMPJ-00011 CXCL2 Protein, Mouse, Recombinant

Gro-beta,GRO β,GROB,melanoma growth stimulatory activity bet...

Mouse E. coli
C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. The expression of mouse MIP-2 is stimulated by endotoxin. The mouse MIP-2 shares approximately 63% aa sequence identity with murine KC, another mouse alpha chemokine, which is induced by PDGF. It has been suggested that mouse KC and MIP-2 are the homologs of the hum...
TMPK-00760 IgG1 Fc Protein, Mouse, Recombinant

VH7183,RGD1359539,IgG1,Igh-4

Mouse HEK293 Cells
Recombinant murine Fc fragment contains the hinge region, CH2, and CH3 region of the mouse IgG1 isotype. IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflammation, and target Ig to particular tissues.
TMPK-01035 SP17 Protein, Mouse, Recombinant (His)

SPA17,Sperm protein 17,CT22,Sp17-1

Mouse E. coli
Sperm protein 17 (Sp17) is a highly conserved mammalian protein characterized in rabbit, mouse, monkey, baboon, macaque, human testis and spermatozoa. mRNA encoding Sp17 has been detected in a range of murine and human somatic tissues. It was also recognized in two myeloma cell lines and in neoplastic cells from patients with multiple myeloma and ovarian carcinoma. SP17 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 1...
TMPK-00624 CD200R1/CRTR2 Protein, Human, Recombinant (hFc)

MOX2R,CRTR2,CD200R,HCRTR2,CD200 R1,MOX2 receptor,OX2R,CD200 ...

Human HEK293 Cells
CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid and T cell lineage. A recent report focused attention on a family of CD200Rs, but concluded that only one member used CD200 as its ligand. CD200R1/CRTR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 53....
TMPJ-00692 GAS7 Protein, Human, Recombinant (His)

GAS-7,GAS7,Growth Arrest-Specific Protein 7,KIAA0394

Human E. coli
Growth Arrest-Specific Protein 7 (GAS7) is expressed primarily in terminalaly differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 may play a role in neuronal development by promoting maturation and morphological differentiation of cerebellar neurons. Inhibition of GAS7 production in terminally differentiating cultures of embryonic murine cerebullum impedes neurite outgrowth. The hyper-expression of GAS7 may play an major role in the initiation and development...
TMPK-01262 CD200R1/CRTR2 Protein, Cynomolgus, Recombinant (His)

CD200 receptor 1,OX2R,MOX2R,CD200 R1,MOX2 receptor,CD200R,HC...

Cynomolgus HEK293 Cells
CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid and T cell lineage. A recent report focused attention on a family of CD200Rs, but concluded that only one member used CD200 as its ligand. CD200R1/CRTR2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight i...
TMPK-00623 CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi), Biotinylated

CRTR2,MOX2R,OX2R,CD200 R1,HCRTR2,CD200 receptor 1,MOX2 recep...

Human HEK293 Cells
CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid and T cell lineage. A recent report focused attention on a family of CD200Rs, but concluded that only one member used CD200 as its ligand. CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted...
TMPK-00974 SP17 Protein, Human, Recombinant (His)

Sperm protein 17,SPA17,CT22,Sp17-1

Human E. coli
Sperm protein 17 (Sp17) is a highly conserved mammalian protein characterized in rabbit, mouse, monkey, baboon, macaque, human testis and spermatozoa. mRNA encoding Sp17 has been detected in a range of murine and human somatic tissues. It was also recognized in two myeloma cell lines and in neoplastic cells from patients with multiple myeloma and ovarian carcinoma. SP17 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 1...
TMPK-00622 CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi)

OX2R,CD200R,MOX2R,CD200 R1,CRTR2,HCRTR2,CD200 receptor 1,MOX...

Human HEK293 Cells
CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid and T cell lineage. A recent report focused attention on a family of CD200Rs, but concluded that only one member used CD200 as its ligand. CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular wei...
TMPK-01385 CRTAM Protein, Canine, Recombinant (His)

CRTAM,CD355 antigen,CD355

Canine HEK293 Cells
Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNγ by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis. CRTAM Pr...
TMPY-00641 LEC/CCL16 Protein, Human, Recombinant (His)

SCYL4,HCC-4,ILINCK,LMC,SCYA16,NCC-4,CKb12,Mtn-1,LCC-1,LEC,ch...

Human E. coli
CCL16, a chemokine poorly characterized at the functional level. Human CCL16 is a member of the CC family, and its gene maps to human chromosome 17q. In the mouse, only a pseudogene has been identified to date. CCL16 is a functional ligand for CCR1, CCR2, CCR5, and CCR8. Recombinant CCL16 demonstrated chemotactic activity on human monocytes and lymphocytes. Based on the ability of human chemokines to exert activity on and bind to murine receptors, the TSA mouse adenocarcinoma cell line was trans...
TMPY-05014 INSL6 Protein, Human, Recombinant (His)

RIF1,insulin-like 6

Human HEK293 Cells
INSL6 (Insulin-Like 6) is a Protein Coding gene. An important paralog of this gene is RLN1. The protein encoded by this gene contains a classical signature of the insulin superfamily and is significantly similar to relaxin and relaxin-like factor. INSL6 is a newly identified insulin/relaxin family peptide hormone that is predominantly expressed by the male germ cells in testes. It may have a role in sperm development and fertilization. A recent murine study demonstrated that INSL6-knockout resul...
TMPJ-01079 TFF2 Protein, Mouse, Recombinant (His)

SP,Trefoil Factor 2,Spasmolytic polypeptide,Tff2,Sml1

Mouse HEK293 Cells
Recombinant Murine TFF-2 is an 11.9 kDa polypeptide of 106 amino acid residues, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds. The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility and gastric acid secretion. Recent data suggests a potential role for TFF2 in acute a...
TMPY-03969 SUSD4 Protein, Human, Recombinant (mFc)

sushi domain containing 4,PRO222

Human HEK293 Cells
SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and testis but not other tissues. In brains, SUSD4 is highly expressed in the white matter on oligodendrocytes/axons, and in eyes, it is exclusively expressed on the photoreceptor outer segments. In in vitro complement assays, SUSD4 augments the alternative but not the classical path...
TMPJ-00451 IL-16 Protein, Human, Recombinant

Interleukin-16,IL16,Lymphocyte Chemoattractant Factor,IL-16,...

Human E. coli
Interleukin-16 (IL-16) is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, human IL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-...
TMPK-00971 CRTAM Protein, Mouse, Recombinant (His)

CRTAM,CD355,CD355 antigen

Mouse HEK293 Cells
Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNγ by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis. CRTAM Pr...
TMPJ-00079 IL-11 Protein, Mouse, Recombinant (hFc)

IL-11,Il11,白细胞介素,白介素,Interleukin-11

Mouse HEK293 Cells
Interleukin-11(IL-11) is a secreted protein and belongs to the IL-6 superfamily. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induceacute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cellproliferation and differentiation and could be use as a therapeutic for osteoporosis. IL-11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thicknes...
TMPY-02891 PSG6 Protein, Human, Recombinant (His)

PSG12,PSG6,PSBG-6,pregnancy specific β-1-glycoprotein 6,PSG1...

Human Baculovirus Insect Cells
PSG6 is a pregnancy-specific glycoprotein(PSG). PSGs are secreted proteins produced by the rodent and primate placenta and play a critical role in pregnancy success. The levels of PSGs are highest during the third trimester of pregnancy, a time marked by the most profound suppression of MS disease attacks. PSGs regulate T-cell function. The regulation of T-cell function during pregnancy is likely the result of significant hormonal changes and may well involve immunoregulatory proteins derived fr...
TMPY-00963 ASAH2 Protein, Mouse, Recombinant (His)

N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) ...

Mouse HEK293 Cells
ASAH2 (N-acylsphingosine amidohydrolase 2), also known as neutral ceramidase, is a type II integral membrane protein that can be cleaved to produce a soluble secreted protein. The enzyme is abundant in the brush border membranes of the intestine, and also expressed in several tissues such as kidney, brain and liver. The primary structure of ASAH2/neutral ceramidase is highly conserved from bacteria to humans, however, there is a clear difference in the molecular architecture. The murine ASAH2 po...
TMPY-02117 Marapsin Protein, Human, Recombinant (His)

UNQ1884/PRO4327,protease, serine 27,CAPH2,MPN

Human HEK293 Cells
The name "Pancreasin" because it is transcribed strongly in the pancreas. This secreted, tryptic serine protease, also known as Marapsin or PRSS27 (Protease, serine, 27), is a member of the peptidase S1 family. Pancreasin is inhibited by benzamidine and leupeptin but resists several classic inhibitors of trypsin. Marapsin was constitutively expressed in nonkeratinizing stratified squamous epithelia of human esophagus, tonsil, cervix, larynx, and cornea. In fact, marapsin was the second most stro...
TMPY-02838 FGFBP3 Protein, Human, Recombinant (His)

C10orf13,FGF-BP3,fibroblast growth factor binding protein 3

Human Baculovirus Insect Cells
FGFBP3 is a member of the fibroblast growth factor-binding protein family. Members of this family binds and activates FGF-1 and FGF-2, thereby contributing to tumor angiogenesis. Fibroblast growth factors (FGFs) are important regulators of cell migration, proliferation and differentiation, e.g., during embryogenesis and wound healing, and under several pathological conditions including tumor growth and tumor angiogenesis. Expression of FGF-BP increases after injury to murine and human skin, in p...
TMPJ-00674 RANK/TNFRSF11A Protein, Mouse, Recombinant (His)

Receptor activator of NF-KB,TNFRSF11A,Osteoclast differentia...

Mouse HEK293 Cells
Receptor activator of NF-κB(RANK,TNFRSF11A) belongs to one member of tumor necrosis factor receptor family.It is a receptor for TNFSF11/RANKL/TRANCE/OPGL. This gene encodes a type 1 membrane protein with a 30 amino acids (aa) signal peptide, 184 aa extracellular region , a 20 aa transmembrane domain and a 391 aa cytoplasmic region. Human and murine RANK share 81% aa identity in their extracellular domains. RANK is ubiquitous highly expressed in trabecular bone, thymus, small intestine, lung, br...
TMPY-02597 IL-37 Protein, Human, Recombinant

FIL1Z,IL-37,白细胞介素,IL37,IL1F7,IL-1RP1,FIL1(ζ),IL1RP1,FIL1,白介素...

Human E. coli
Interleukin 1 family member 7, or interleukin 37 (IL1F7 / IL37 / IL-1H4) is a secretory protein belonging to the Interleukin 1 family. IL-1F7 was localized in human peripheral monocytic cells. It has been localized the expression of IL-1F7b protein in discrete cell populations including plasma cells and tumor cells. These data suggest that IL-1F7 may be involved in immune response, inflammatory diseases, and/or cancer. Through constructing an adenoviral vector that allows high-level expression i...
TMPY-00004 CD28 Protein, Rat, Recombinant (hFc)

CD28 molecule

Rat HEK293 Cells
CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell r...
TMPY-01909 Elafin Protein, Human, Recombinant (His)

WAP3,ESI,peptidase inhibitor 3,SKALP,cementoin,MGC13613,WFDC...

Human HEK293 Cells
Elafin, also known as Elastase-specific inhibitor, Peptidase inhibitor 3, Protease inhibitor WAP3, Skin-derived antileukoproteinase, WAP four-disulfide core domain protein 14, PI3, WAP3 and WFDC14, is a secreted protein that contains one WAP domain. Elafin / PI3 consists of two domains: the transglutaminase substrate domain (cementoin moiety) and the elastase inhibitor domain. The transglutaminase substrate domain at the N-terminus serves as an anchor to localize elafin covalently to specific si...
TMPY-03504 CBFB Protein, Human, Recombinant (His)

core-binding factor, β subunit,core-binding factor, beta sub...

Human E. coli
CBFB is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). CBFB is a non-DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enh...
TMPY-04554 JNK1 Protein, Human, Recombinant (GST)

PRKM8,JNK,JNK-46,JNK21B1/2,JNK1A2,mitogen-activated protein ...

Human Baculovirus Insect Cells
Mitogen-activated protein kinase 8 (MAPK8), also known as JNK1, is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. The protein kinases JNK1 has been found to serve as critical molecular links between obesity, metabolic inflammation, and disorders of glucose homeostasis. It is critically involved in ...
TMPY-01416 OLFM4 Protein, Human, Recombinant (His)

hGC-1,GC1,OLM4,bA209J19.1,GW112,olfactomedin 4,OlfD,hOLfD,UN...

Human HEK293 Cells
Olfactomedin-4, also known as G-CSF-stimulated clone 1 protein, Antiapoptotic protein GW112, and OLFM4, is a secreted protein that contains one olfactomedin-like domain. The OLFM4 gene was recently reported to inhibit various apoptotic pathways and promote the proliferation of cancer cells, suggesting that OLFM4 might serve as a diagnostic marker for human cancers. Thus, OLFM4 mRNA might be a useful tool to support the diagnosis of cancer, irrespective of the clinical stages. It is overexpressed...
TMPY-01249 Cathepsin V Protein, Human, Recombinant (His)

CTSV,cathepsin V,MGC125957,CATL2,CTSU,CTSL2

Human HEK293 Cells
Cathepsin V (CTSV), also known as Cathepsin L2, CTSL2, and CATL2, is a member of the peptidase C1 family. It is predominantly expressed in the thymus and testis. Cathepsin V is also expressed in corneal epithelium, and to a lesser extent in conjuctival epithelium and skin. It is a lysosomal cysteine proteinase that may play an important role in corneal physiology. It has about 75% protein sequence identity to murine cathepsin L. The fold of this enzyme is similar to the fold adopted by other mem...

重组蛋白

BDNF Protein, Human/Murine/Rat, Recombinant
Cat.No: TMPJ-00135
Species: Human,Mouse,Rat
Expression System: E. coli
AKT1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04552
Species: Human
Expression System: Baculovirus Insect Cells
AKT3 Protein, Mouse, Recombinant (aa 106-479, His & GST)
Cat.No: TMPY-04574
Species: Mouse
Expression System: Baculovirus Insect Cells
AKT3 Protein, Mouse, Recombinant (aa 106-479)
Cat.No: TMPY-04446
Species: Mouse
Expression System: Baculovirus Insect Cells
Murine polyomavirus (MPyV) (strain Kilham) VP2 Protein (His)
Cat.No: TMPH-02986
Species: MPyV
Expression System: E. coli
AKT2 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04387
Species: Human
Expression System: Baculovirus Insect Cells
Murine polyomavirus (MPyV) (strain Kilham) VP1 Protein (His)
Cat.No: TMPH-02984
Species: MPyV
Expression System: Baculovirus Insect Cells
Moloney murine leukemia virus (MoMLV) (isolate Shinnick) Gag polyprotein (GST)
Cat.No: TMPH-02465
Species: MoMLV
Expression System: E. coli
Murine polyomavirus (MPyV) (strain Kilham) VP1 Protein (E. coli, His)
Cat.No: TMPH-02985
Species: MPyV
Expression System: E. coli
AKT3 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04553
Species: Human
Expression System: Baculovirus Insect Cells
Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein, Mouse, MHC (His & Avi)
Cat.No: TMPK-01414
Species: Mouse
Expression System: HEK293 Cells
TREML2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01648
Species: Human
Expression System: HEK293 Cells
PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPK-00471
Species: Mouse
Expression System: HEK293 Cells
PVRIG Protein, Mouse, Recombinant (hFc & Avi)
Cat.No: TMPK-00470
Species: Mouse
Expression System: HEK293 Cells
CXCL2 Protein, Mouse, Recombinant
Cat.No: TMPJ-00011
Species: Mouse
Expression System: E. coli
IgG1 Fc Protein, Mouse, Recombinant
Cat.No: TMPK-00760
Species: Mouse
Expression System: HEK293 Cells
SP17 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01035
Species: Mouse
Expression System: E. coli
CD200R1/CRTR2 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00624
Species: Human
Expression System: HEK293 Cells
GAS7 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00692
Species: Human
Expression System: E. coli
CD200R1/CRTR2 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01262
Species: Cynomolgus
Expression System: HEK293 Cells
CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00623
Species: Human
Expression System: HEK293 Cells
SP17 Protein, Human, Recombinant (His)
Cat.No: TMPK-00974
Species: Human
Expression System: E. coli
CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00622
Species: Human
Expression System: HEK293 Cells
CRTAM Protein, Canine, Recombinant (His)
Cat.No: TMPK-01385
Species: Canine
Expression System: HEK293 Cells
LEC/CCL16 Protein, Human, Recombinant (His)
Cat.No: TMPY-00641
Species: Human
Expression System: E. coli
INSL6 Protein, Human, Recombinant (His)
Cat.No: TMPY-05014
Species: Human
Expression System: HEK293 Cells
TFF2 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01079
Species: Mouse
Expression System: HEK293 Cells
SUSD4 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-03969
Species: Human
Expression System: HEK293 Cells
IL-16 Protein, Human, Recombinant
Cat.No: TMPJ-00451
Species: Human
Expression System: E. coli
CRTAM Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00971
Species: Mouse
Expression System: HEK293 Cells
IL-11 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00079
Species: Mouse
Expression System: HEK293 Cells
PSG6 Protein, Human, Recombinant (His)
Cat.No: TMPY-02891
Species: Human
Expression System: Baculovirus Insect Cells
ASAH2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00963
Species: Mouse
Expression System: HEK293 Cells
Marapsin Protein, Human, Recombinant (His)
Cat.No: TMPY-02117
Species: Human
Expression System: HEK293 Cells
FGFBP3 Protein, Human, Recombinant (His)
Cat.No: TMPY-02838
Species: Human
Expression System: Baculovirus Insect Cells
RANK/TNFRSF11A Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00674
Species: Mouse
Expression System: HEK293 Cells
IL-37 Protein, Human, Recombinant
Cat.No: TMPY-02597
Species: Human
Expression System: E. coli
CD28 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-00004
Species: Rat
Expression System: HEK293 Cells
Elafin Protein, Human, Recombinant (His)
Cat.No: TMPY-01909
Species: Human
Expression System: HEK293 Cells
CBFB Protein, Human, Recombinant (His)
Cat.No: TMPY-03504
Species: Human
Expression System: E. coli
JNK1 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04554
Species: Human
Expression System: Baculovirus Insect Cells
OLFM4 Protein, Human, Recombinant (His)
Cat.No: TMPY-01416
Species: Human
Expression System: HEK293 Cells
Cathepsin V Protein, Human, Recombinant (His)
Cat.No: TMPY-01249
Species: Human
Expression System: HEK293 Cells
Cat. No. Product Name Target Signaling Pathways
T71293 Nifuroxazide-d4

Nifuroxazide-d4 is intended for use as an internal standard for the quantification of nifuroxazide by GC- or LC-MS. Nifuroxazide is a nitrofuran antibiotic. It is active against strains of the enteropathogenic bacteria C. jejuni, Salmonella, Y. enterocolitica, Shigella, and E. coli. It inhibits quorum sensing and virulence factor production in P. aeruginosa. Nifuroxazide inhibits STAT3 activity in a reporter assay and decreases viability of U266 and INA-6 myeloma cells, which have constitutive S...
T70882 Orlistat-d3

Orlistat-d3 is intended for use as an internal standard for the quantification of orlistat by GC- or LC-MS. Orlistat is a digestive lipase inhibitor. It inhibits diacylglycerol lipase α (DAGLα), DAGLβ, α/β-hydrolase domain-containing protein 12 (ABHD12), ABHD16A, and platelet-activating factor acetylhydrolase (PAF-AH; IC50s = 0.06, 0.1, 0.08, 0.03, and 0.05 µM, respectively), as well as pancreatic lipase and hormone-sensitive lipase (IC50s = 0.65 and 2.1 µg/ml, respectively) but does not inhibit...
T69966 Roxadustat-d5

Roxadustat-d5 is intended for use as an internal standard for the quantification of roxadustat by GC- or LC-MS. Roxadustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH; IC50s = 1.4, 1.26, and 1.32 µM for HIF-PH1, HIF-PH2, and HIF-PH3, respectively). It is selective for HIF-PH over other 2-oxoglutarate-dependent dioxygenases, including lysine-specific demethylase 5A (KDM5A), KDM5B, -5C, -5D, and -6B (IC50s = >100 µM for all). Roxadustat (10-200 µM) stabilizes HIF-1α and ...
T36055 Nitisinone-13C6

Nitisinone-13C6

Nitisinone-13C6is intended for use as an internal standard for the quantification of nitisinone by GC- or LC-MS. Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homogentisate in the tyrosine catabolic pathway.1Nitisinone increases urinary levels of HPPA and 4-hydroxyphenyllactate (HPLA) in rats when administered at a dose of 10 mg/kg. Nitisinone (3 mg/kg) prevents the neonatal lethality of fumarylacetoacetate hydrolase (F...

同位素标记化合物

Nifuroxazide-d4
Cat.No: T71293
Synonym:
Target:
Orlistat-d3
Cat.No: T70882
Synonym:
Target:
Roxadustat-d5
Cat.No: T69966
Synonym:
Target:
Nitisinone-13C6
Cat.No: T36055
Synonym: Nitisinone-13C6
Target:
TargetMol Loading
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