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Search Results for " metabolic diseases "

Targets Recommended: Others

64

抑制剂 & 化合物

15

天然产物

14

化合物库

14

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name
L2560	代谢化合物库		2320 compounds
	2320 种代谢途径相关的化合物，可用于高通量和高内涵筛选。
L5300	线粒体靶向库		812 compounds
	812 种具有潜在或确定线粒体靶向活性的化合物，以促进针对线粒体的药物研究；
L2540	肠道微生物代谢化合物库		614 compounds
	614 种肠道微生物代谢物的集合，可以用于高通量和高内涵筛选；
L1510	核受体化合物库		531 compounds
	531 个核受体作用化合物的独特集合，可用于高通量筛选和高内涵筛选；
L2501	人内源代谢化合物库 Plus		1283 compounds
	1283种内源性生物活性化合物的独特集合，用于高通量、高内涵筛选。
L1600	激酶抑制剂库		2720 compounds
	2720 种激酶抑制剂/调节剂的独特集合，用于特定靶向激酶，可用于高通量筛选和高内涵筛选；
L6600	胃肠炎天然产物库		219 compounds
	219 种胃肠炎相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L1120	AMPK靶向分子库		80 compounds
	80 个靶向AMPK 的分子集合，可用于高通量和高内涵筛选；
L2510	脂代谢化合物库		492 compounds
	492 个脂代谢相关的化合物集合，可用于高通量和高内涵筛选；
L2500	人内源代谢化合物库		499 compounds
	499 种内源性生物活性化合物的独特集合，用于高通量、高内涵筛选；
L9600	多肽分子库		791 compounds
	791 种多肽类分子，可用于多肽药物开发及信号转导通路和作用机制研究；
L2520	糖代谢化合物库		702 compounds
	702 种糖代谢相关的化合物，可用于高通量和高内涵筛选；
L6400	海洋天然产物库		144 compounds
	144 种海洋来源的单体化合物，是药物开发、药理研究等领域的有力工具；
L7110	抗高血压化合物库		678 compounds
	678 种高血压相关的小分子，用于高通量和高内涵筛选；

化合物库

代谢化合物库

Cat.No: L2560

Compounds: 2320

线粒体靶向库

Cat.No: L5300

Compounds: 812

肠道微生物代谢化合物库

Cat.No: L2540

Compounds: 614

核受体化合物库

Cat.No: L1510

Compounds: 531

人内源代谢化合物库 Plus

Cat.No: L2501

Compounds: 1283

激酶抑制剂库

Cat.No: L1600

Compounds: 2720

胃肠炎天然产物库

Cat.No: L6600

Compounds: 219

AMPK靶向分子库

Cat.No: L1120

Compounds: 80

脂代谢化合物库

Cat.No: L2510

Compounds: 492

人内源代谢化合物库

Cat.No: L2500

Compounds: 499

多肽分子库

Cat.No: L9600

Compounds: 791

糖代谢化合物库

Cat.No: L2520

Compounds: 702

海洋天然产物库

Cat.No: L6400

Compounds: 144

抗高血压化合物库

Cat.No: L7110

Compounds: 678

Cat. No.	Product Name	Target	Signaling Pathways
TD0093	Oil Red O	Others	Others
	Oil Red O 用于制备染色溶液，可用于检测组织学冷冻切片中的脂质。
T12998	SR10067	Others; Autophagy	Autophagy; Others
	SR10067 是选择性的Rev-Erbα/β的激动剂，其对Rev-Erbβ 和Rev-Erbα 的IC50分别为 160 nM 和 170 nM。SR10067可以透过大脑的。SR10067具有抗焦虑活性。
T19700	IBC 293 IBC293,1-异丙基-1H-1,2,3-苯并噻唑-5-羧酸,IBC-293	GPR	Endocrinology/Hormones; GPCR/G Protein
	IBC 293 对 GPR109B 的选择性高于烟酸受体 GPR109A。 IBC 293 是 GPR109B 的高选择性激动剂，GPR109B 是一种在脂肪细胞中表达的人类孤儿 G 蛋白偶联受体。
T23209	Qc1 Qc 1	Dehydrogenase	Metabolism
	Qc1是苏氨酸脱氢酶（TDH）的抑制剂，可用于有关代谢性疾病的研究。
T15448	GW-1100 GW 1100,GW1100	GPR	Endocrinology/Hormones; GPCR/G Protein
	GW-1100是选择性的 GPR40 和 FFAR1 拮抗剂，可用于研究糖尿病和代谢疾病。
T11758	KI696 isomer	Nrf2	Immunology/Inflammation
	KI696 isomer 是 KI696 的异构体，是一种亲和力较低的探针，可用于研究免疫和代谢疾病。
T22832	H-8 hydrochloride	PKA	Tyrosine Kinase/Adaptors
	H-8 hydrochloride 是一种具有可逆性和 ATP 竞争性的 PKA 抑制剂。可用研究代谢疾病。
T34385	Ronacaleret HCl SB 751689,SB 751689A,SB-751689A,SB-751689,SB751689A,SB751689	CaSR	GPCR/G Protein
	Ronacaleret HCl (SB-751689) 是一种小分子 CaSR 拮抗剂，可用于治疗内分泌与代谢疾病、皮肤和肌肉骨骼疾病。
T39350	Sebetralstat KVD900	Others	Others
	Sebetralstat (KVD900) 是一种血浆激肽释放酶抑制剂，可用于代谢性疾病的研究。
T21457	Carbazeran UK-31557,UK31,557,UK-31,557,UK31557,UK 31557,卡巴折伦,UK 31,557	PDE	Metabolism
	Carbazeran (UK-31,557) 是 PDE2 和 PDE3 的抑制剂，可用于代谢疾病的研究。 Carbazeran 在体内显示出正性肌力和变时性作用 (EC50 = 100 μM)。
T60908	SARM1-IN-2	Others	Others
	SARM1-IN-2 是一种有效的 SARM1 抑制剂，可用于研究代谢系统和神经系统相关疾病。
T11978	McN3716 NSC359682,Methyl palmoxirate	Mitochondrial Metabolism; CPT	Metabolism
	McN3716 是一种肉碱棕榈酰转移酶 I (CPT-1) 抑制剂，可用于研究代谢疾病。
T40287	FATP1-IN-2	Others	Others
	FATP1-IN-2 是一种脂肪酸转运蛋白1 (FATP1) 抑制剂，具有口服活性，可用于研究肥胖和代谢疾病。
T61144	Hepcidin antagonist-1	Others	Others
	Hepcidin antagonist-1 是一种铁调素拮抗剂。Hepcidin antagonist-1 可用于研究像缺铁疾病和贫血类的代谢紊乱。
T9089	FTO-IN-1 UUN44923	Others	Others
	UUN44923 是脂肪及肥胖相关酶(FTO) 抑制剂(IC50<1 μM)。其中FTO-IN-1 (UUN44923) 可用于研究癌症。
T37994	16-hydroxy Hexadecanoic Acid Juniperic acid
	16-hydroxy Hexadecanoic Acid (Juniperic acid) 是从拟南芥叶和茎中分离出的化合物，可用于预防、缓解或治疗代谢性疾病。
T13898	SPD-473 citrate BTS 74398 citrate	Dopamine Receptor; 5-HT Receptor; Norepinephrine	GPCR/G Protein; Neuroscience
	SPD-473 citrate (BTS 74398 citrate) 是多巴胺重摄取抑制剂、去甲肾上腺素转运蛋白（NET）抑制剂和5-羟色胺重摄取抑制剂，可用于研究神经系统疾病和内分泌与代谢疾病。
T60060	ACSS2-IN-2 MTB-9655	Fatty Acid Synthase	Metabolism
	ACSS2-IN-2 (MTB-9655) 是酰基辅酶 A 合成酶短链家族成员 2 (ACSS2) 抑制剂。ACSS2-IN-2 可抑制 ACSS2 活性，IC50 为 3.8 nM。ACSS2-IN-2 可用于多种疾病的研究，如病毒感染、代谢紊乱、神经精神疾病、炎症/自身免疫疾病和癌症。
T68053	Denagliptin GW823093	DPP-4	Proteases/Proteasome
	Denagliptin是一种小分子二肽基肽酶IV（DPP-4）抑制剂，可用于治疗内分泌于代谢疾病，可用于研究2型糖尿病。
T61964	RXFP3/4 agonist 2	RXFP receptor	GPCR/G Protein
	RXFP3/4 agonist 2 是一种高效的非肽双 RXFP3/4 激动剂，诱导 RXFP3 和 β-arrestin-2 之间的相互作用，可用于研究代谢异常引起的疾病。
T111959	IFB-088 acetate	Others	Others
	IFB-088 acetate 是一种苄基胍衍生物，可用于治疗与PPP1R15A 途径相关并与蛋白质错误折叠应激相关的疾病和癌症，如tau 病、突触核蛋白病、多谷氨酰胺和多丙氨酸疾病、白质营养不良、囊性纤维化、多发性硬化症、溶酶体储存障碍、淀粉样变性疾病、炎症、代谢障碍、心血管疾病、骨质疏松症、神经系统创伤等等。
T77194L	D-Ribose 5-phosphate disodium dihydrate	Endogenous Metabolite	Metabolism
	D-Ribose 5-phosphate disodium dihydrate 参与磷酸戊糖途径，是磷酸戊糖途径的中间产物，可用于研究由核黄素缺乏引起的眼部疾病和内分泌与代谢疾病。
T10035	10,12-Tricosadiynoic acid TDA,TCDA	Acyltransferase	Metabolism
	10,12-Tricosadiynoic acid 是一种口服有效的酰基辅酶 A 氧化酶-1 (ACOX1) 抑制剂，具有高特异性，选择性，高亲和力的特点。10,12-Tricosadiynoic acid 可改善线粒体脂质和 ROS 代谢，在高脂饮食或肥胖引起的代谢性疾病中有研究的价值。
T23512	VU 0364739 hydrochloride VU 0364739 HCl	Apoptosis; Phospholipase	Apoptosis; Metabolism
	VU 0364739 hydrochloride (VU 0364739 HCl) 是一种具有选择性和高效性的磷脂酶 D2 (PLD2) 抑制剂，对 PLD2 和 PLD1 的 IC50 分别为 20 和 1500 nM。VU 0364739 hydrochloride 具有潜在的抗癌活性，诱导细胞凋亡，可用于研究癌症和代谢相关疾病。
T83971L	LCC-12 FA	Antiviral; Antibacterial	Immunology/Inflammation; Microbiology/Virology
	LCC-12 FA 是一种由二甲双胍组成的二聚体，通过靶向线粒体铜（ii）从而诱导 NAD（H）池减少。LCC-12 FA 可减少细菌和病毒感染小鼠模型中的炎症，可用于研究代谢疾病。
T61932	Nesuparib JPI-547/OCN-201	PARP; Wnt/beta-catenin	Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Stem Cells
	Nesuparib (JPI-547/OCN-201) 是一种有效的PARP抑制剂，对PARP 和TNKS1具有抑制作用。Nesuparib 具有抗肿瘤活性，可用于治疗肿瘤、内分泌与代谢疾病、泌尿生殖系统疾病，可用于研究神经性疼痛、神经退行性疾病和心血管疾病。
T38683	SCD1 inhibitor-3 SCD1-IN-3,SCD1 inhibitor-3,SCD1 inhibitor 17a	Dehydrogenase	Metabolism
	SCD1 inhibitor-3 (ML-270) 是一种高效、口服的化合物，可以抑制SCD1，且安全性极高。 SCD1 inhibitor-3 显示出在代谢疾病(包括肥胖、二型糖尿病和血脂异常，以及痤疮和癌症等各种皮肤病)方面的巨大研究潜力。
T77577	SLU-PP-332	Estrogen/progestogen Receptor	Endocrinology/Hormones
	SLU-PP-332 是一种泛雌激素受体相关受体 (ERR) 激动剂，其对 ERRα, ERRβ 以及 ERRγ 具有很高的亲和力，EC50 值分别为 98、230 以及 430 nM。SLUPP-332 可增强骨骼肌细胞系的线粒体功能和细胞呼吸，增加 IIa 型氧化骨骼肌纤维并增强了运动耐力。SLU-PP-332 具有研究代谢性疾病以及肌肉功能改善的潜力，可能用于改善代谢紊乱和衰老。
T9729	AGI-43192	Others	Others
	AGI-43192是一种有效的，可渗透进血脑屏障的蛋氨酸腺苷转移酶 2A (MAT2A) 抑制剂。AGI-43192抑制 s -腺苷蛋氨酸(SAM)生成代谢酶和蛋氨酸腺苷转移酶2A (MAT2A)，具有研究 SAM 调节在中枢神经系统 (CNS) 中的作用和治疗癌症疾病的潜力。
T9025	KY19382 2H-Indol-2-one, 5,6-dichloro-3-[1,3-dihydro-3-(methoxyimino)-2H-indol-2-ylidene]-1,3-dihydro-Ky19382,A3051	Others; GSK-3; Wnt/beta-catenin	Cytoskeletal Signaling; Others; PI3K/Akt/mTOR signaling; Stem Cells
	KY19382 (2H-Indol-2-one, 5,6-dichloro-3-[1,3-dihydro-3-(methoxyimino)-2H-indol-2-ylidene]-1,3-dihydro-Ky19382) 是一种具有口服活性的 CXXC5-DVL (IC50:19 nM) 和 GSK3β (IC50:10 nM) 的双重抑制剂。它通过对 CXXC5-DVL 相互作用和 GSK3β 活性的抑制作用激活 Wnt/β-catenin 信号传导。它可用于高脂饮食诱发的代谢性疾病的研究。
T28573	Ro 23-7637 Ro-23-7637	Others	Others
	Ro 23-7637 is a drug may have potent to treat metabolic diseases.
T33423	MK-0916 MK 0916	Others	Others
	MK-0916 is a 11β-hydroxysteroid dehydrogenase type 1 inhibitor indicated for the treatment of type 2 diabetes and metabolic syndrome as well as obesity-related diseases.
T31940	Glucosylgalactosylhydroxylysine Hydroxylysine-glucose-galactose	Others	Others
	Glucosylgalactosylhydroxylysine is a bone formation and bone resorption marker that is related to bone turnover processes during growth and development as well as metabolic bone diseases.
T13260	Gastrin/CCK antagonist 1	cholecystokinin	GPCR/G Protein
	Gastrin/CCK antagonist 1 是一种有效的 gastrin/CCK 拮抗剂，可用于研究代谢系统相关疾病。
T63818	Omesdafexor	Others	Others
	Omesdafexor 是 FXR 激动剂，能够用于研究肝病或代谢性炎症引起的疾病。
T14563	BI-4916 BI 4916,BI4916	Dehydrogenase	Metabolism
	BI-4916 是一种选择性磷酸甘油酸脱氢酶 (PHGDH) 抑制剂，可抑制 SSP,可减少癌细胞迁移。BI-4916 可用于研究癌症和代谢疾病。
T79624	PDE4-IN-14	Others	Others
	PDE4-IN-14 (化合物1)是PDE4抑制剂，适用于研究与PDE4关联的疾病（例如炎症性和免疫性疾病、癌症及代谢性疾病等）。
T75160	FXR agonist 5	Others	Others
	FXR agonist5 (compound 1) 是一种FXR 激动剂。FXR agonist5 可用于研究代谢性炎症引起的疾病或紊乱。
T83546	(D-Trp8,D-Cys14)-Somatostatin-14
	"(D-Trp8,D-Cys14)-Somatostatin-14"为一种生长抑素合成类似物，主要用于代谢相关疾病研究。
T79160	PROTAC PTPN2 degrader-2	Phosphatase	Metabolism
	PROTACPTPN2 degrader-2（example 187B）作为PTPN2降解剂，展现出对研究癌症和代谢性疾病的有效性。
T35040	Vatiquinone EPI-743,EPI743,alpha-Tocotrienol quinone. ATQ3,EPI 743	Others	Others
	Vatiquinone, also known as EPI 743, is an orally bioavailable para-benzoquinone being developed for inherited mitochondrial diseases. The mechanism of action of EPI-743 involves augmenting the synthesis of glutathione, optimizing metabolic control, enhanc
T74732	PROTAC PTPN2 degrader-1	Others	Others
	PROTACPTPN2 degrader-1 (compound example 77) 是一种有效的 PTPN2降解剂。PROTACPTPN2 degrader-1 具有研究癌症或代谢性疾病的潜力。
T60441	DK3	Others	Others
	DK3 是雌激素相关受体 α(ERRα)的一种有效的选择性激动剂，ERRα是癌症和代谢性疾病的潜在药物靶点[1]。
T84659	DOG-IM4	Others	Others
	DOG-IM4 用于合成携带抗原编码核酸的纳米颗粒，适用于研究自身免疫性疾病、罕见血液或代谢疾病、过敏、癌症及传染病的靶向治疗。
T72596	RORγt modulator 5	Others	Others
	RORγt modulator 5 是一种 RORγt 调节剂，Ki 值 <100 nM。RORγt modulator 5 可用于研究 RORy 介导的炎症、代谢、自身免疫和其他疾病。
T72611	GLP-1R agonist 17	Others	Others
	GLP-1R agonist 17，一种表现出极佳激动作用于GLP-1受体的GLP-1受体激动剂，适用于心血管代谢疾病研究。
T74043	Hexanoyl coenzyme A trilithium	Endogenous Metabolite	Metabolism
	Hexanoyl coenzyme A trilithium 是一种广泛存在于动植物体内的化合物，参与生物体的多种代谢，可用于研究代谢异常引起的疾病。
T76526	Ac-D-DGla-LI-Cha-C
	Ac-D-DGla-LI-Cha-C 是一种有效的HCV 蛋白酶抑制剂肽。Ac-D-DGla-LI-Cha-C 可用于癌症、自身免疫性疾病、纤维化疾病、炎症性疾病、神经退行性疾病、感染性疾病、肺部疾病、心脏和血管疾病以及代谢性疾病的研究。
T62350	XO/COX/LOX-IN-1	Others	Others
	XO/COX/LOX-IN-1 是一种黄嘌呤氧化酶/环氧酶/脂氧合酶 XO/COX/LOX 的有效抑制剂。XO/COX/LOX-IN-1 能够用于研究炎症、癌症以及代谢性疾病。
T78738	hnNOS-IN-2	NO Synthase	Immunology/Inflammation
	hnNOS-IN-2（compound 17）是一种针对人神经元一氧化氮合酶（hnNOS）的抑制剂，表现出优秀的代谢稳定性，并可应用于神经退行性疾病的研究工作。

化合物

Cat.No: TD0093

Target: Others

Cat.No: T12998

Target: Others, Autophagy

Cat.No: T19700

Synonym: IBC293,1-异丙基-1H-1,2,3-苯并噻唑-5-羧酸,IBC-293

Target: GPR

Cat.No: T23209

Synonym: Qc 1

Target: Dehydrogenase

Cat.No: T15448

Synonym: GW 1100,GW1100

Target: GPR

Cat.No: T11758

Target: Nrf2

H-8 hydrochloride

Cat.No: T22832

Target: PKA

Ronacaleret HCl

Cat.No: T34385

Synonym: SB 751689,SB 751689A,SB-751689A,SB-751689,SB751689A,SB751689

Target: CaSR

Cat.No: T39350

Synonym: KVD900

Target: Others

Cat.No: T21457

Synonym: UK-31557,UK31,557,UK-31,557,UK31557,UK 31557,卡巴折伦,UK 31,557

Target: PDE

Cat.No: T60908

Target: Others

Cat.No: T11978

Synonym: NSC359682,Methyl palmoxirate

Target: Mitochondrial Metabolism, CPT

Cat.No: T40287

Target: Others

Hepcidin antagonist-1

Cat.No: T61144

Target: Others

Cat.No: T9089

Synonym: UUN44923

Target: Others

16-hydroxy Hexadecanoic Acid

Cat.No: T37994

Synonym: Juniperic acid

SPD-473 citrate

Cat.No: T13898

Synonym: BTS 74398 citrate

Target: Dopamine Receptor, 5-HT Receptor, Norepinephrine

Cat.No: T60060

Synonym: MTB-9655

Target: Fatty Acid Synthase

Cat.No: T68053

Synonym: GW823093

Target: DPP-4

RXFP3/4 agonist 2

Cat.No: T61964

Target: RXFP receptor

IFB-088 acetate

Cat.No: T111959

Target: Others

D-Ribose 5-phosphate disodium dihydrate

Cat.No: T77194L

Target: Endogenous Metabolite

10,12-Tricosadiynoic acid

Cat.No: T10035

Synonym: TDA,TCDA

Target: Acyltransferase

VU 0364739 hydrochloride

Cat.No: T23512

Synonym: VU 0364739 HCl

Target: Apoptosis, Phospholipase

Cat.No: T83971L

Target: Antiviral, Antibacterial

Cat.No: T61932

Synonym: JPI-547/OCN-201

Target: PARP, Wnt/beta-catenin

SCD1 inhibitor-3

Cat.No: T38683

Synonym: SCD1-IN-3,SCD1 inhibitor-3,SCD1 inhibitor 17a

Target: Dehydrogenase

Cat.No: T77577

Target: Estrogen/progestogen Receptor

Cat.No: T9729

Target: Others

Cat.No: T9025

Synonym: 2H-Indol-2-one, 5,6-dichloro-3-[1,3-dihydro-3-(methoxyimino)-2H-indol-2-ylidene]-1,3-dihydro-Ky19382,A3051

Target: Others, GSK-3, Wnt/beta-catenin

Cat.No: T28573

Synonym: Ro-23-7637

Target: Others

Cat.No: T33423

Synonym: MK 0916

Target: Others

Glucosylgalactosylhydroxylysine

Cat.No: T31940

Synonym: Hydroxylysine-glucose-galactose

Target: Others

Gastrin/CCK antagonist 1

Cat.No: T13260

Target: cholecystokinin

Cat.No: T63818

Target: Others

Cat.No: T14563

Synonym: BI 4916,BI4916

Target: Dehydrogenase

Cat.No: T79624

Target: Others

Cat.No: T75160

Target: Others

(D-Trp8,D-Cys14)-Somatostatin-14

Cat.No: T83546

PROTAC PTPN2 degrader-2

Cat.No: T79160

Target: Phosphatase

Cat.No: T35040

Synonym: EPI-743,EPI743,alpha-Tocotrienol quinone. ATQ3,EPI 743

Target: Others

PROTAC PTPN2 degrader-1

Cat.No: T74732

Target: Others

Cat.No: T60441

Target: Others

Cat.No: T84659

Target: Others

RORγt modulator 5

Cat.No: T72596

Target: Others

GLP-1R agonist 17

Cat.No: T72611

Target: Others

Hexanoyl coenzyme A trilithium

Cat.No: T74043

Target: Endogenous Metabolite

Ac-D-DGla-LI-Cha-C

Cat.No: T76526

XO/COX/LOX-IN-1

Cat.No: T62350

Target: Others

Cat.No: T78738

Target: NO Synthase

Cat. No.	Product Name	Target	Signaling Pathways
T3836	Eudesmin	MAPK; S6 Kinase	MAPK; PI3K/Akt/mTOR signaling
	Eudesmin 通过抑制S6K1信号通路来干扰成脂分化，具有抗肿瘤、抗炎和抗菌活性。
T19538	(R)-(-)-1,3-Butanediol	Endogenous Metabolite	Metabolism
	(R)-(-)-1,3-Butanediol 是一种新型生酮酯，可在短时间内快速增加健康成人循环中 r- 和 s-ß-羟基丁酸浓度，可用于研究代谢系统相关疾病。
TN1352	N-(3-Methoxybenzyl-(9z,12z)-octadecadienamide 12顺-亚油酸酰胺,(9Z,12Z)-N-(3-Methoxybenzyl)octadeca-9,12-dienamide,n-3-methoxybenzyl-9z-12z-octadecadienamide,玛卡酰胺杂质10	Drug Metabolite	Metabolism
	N-(3-Methoxybenzyl-(9z,12z)-octadecadienamide ((9Z,12Z)-N-(3-Methoxybenzyl)octadeca-9,12-dienamide) 是一种 Macamide 杂质，可能用于代谢疾病的研究。
TN3050	4'-Methoxyflavanone	Others	Others
	4'-Methoxyflavanone 是一种从天然 Isaria fumosorosea KCH J2中分离得到的黄酮类化合物，可用于研究代谢疾病和心血管疾病。
T4A2456	Gamabufotalin Gamabufagin,日本蟾蜍毒苷元	COX	Immunology/Inflammation; Neuroscience
	Gamabufotalin (Gamabufagin) 是一种蟾蜍甾烯，存在于蟾酥中。它稳定性高，毒性低，被广泛用于癌症的研究。
TN1475	Caulophyllogenin Segetalic acid	IL Receptor; TNF; PPAR; Immunology/Inflammation related	Apoptosis; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism
	Caulophyllogenin 是一种部分 PPARγ 激动剂 (EC50 = 12.6 μM)，来源于 Kalopanax pictus (五加科) 的茎皮。 Caulophyllogenin 抑制促炎细胞因子分泌，可用于预防和治疗炎症性疾病、2 型糖尿病、肥胖和代谢综合征的研究。
T5623	Bisphenol A	Others; Endogenous Metabolite	Metabolism; Others
	Bisphenol A 是酚类内源性代谢合成物，广泛用于环氧树脂和聚碳酸酯塑料的生产。它是生殖、发育和全身毒性物质，常被归类为内分泌干扰物。它与许多疾病有关，包括呼吸系统疾病、心血管疾病、糖尿病、肾脏疾病、肥胖和生殖障碍。
T6S1559	Aurantio-obtusin	Others	Others
	Aurantio-obtusin 是从决明子中分离出的蒽醌类化合物，具有抗炎、抗凝血、抗氧化、抗高血压的活性。它能抑制 IgE 介导的肥大细胞和过敏模型中的过敏反应，具有研究过敏相关疾病的潜力。在大鼠中，它通过内皮细胞 PI3K/AKT/ eNOS 依赖信号通路放松全身动脉，是潜在的新型血管扩张剂。
T8274	3-Methyl-L-histidine	Endogenous Metabolite	Metabolism
	3-Methyl-L-histidine 是一种肉类尤其是鸡肉摄入和大豆制品摄入的生物标记。
T8053	N-Acetyl-L-arginine N-Α-乙酰-L-精氨酸,Ac-Arg-OH	Endogenous Metabolite	Metabolism
	N-Acetyl-L-arginine (Ac-Arg-OH) 是一种胍基诺化合物，被发现存在于血液渗析性肾不足儿童患者血清中的。
T19204	Compound 2	Others	Others
	Compound 2 is used for the research of metabolic bone diseases.
T78466	Erythronic acid potassium	Endogenous Metabolite	Metabolism
	Erythronic acid potassium为糖类内源性代谢物，关键作用于高尿酸血症发病及改善过程，并与转醛缩酶缺乏症相关的线粒体功能障碍有关，常用于代谢性疾病研究。
TN7261	Tridocosahexaenoylglycerol TG-DHA,Meganol D	Others	Others
	Tridocosahexaenoylglycerol (TG-DHA)是一种改善小鼠自身免疫性脑脊髓炎的口服有效膳食补充剂，展现出对神经退行性疾病的有益作用，并能改善糖尿病视网膜病变黄斑功能。该化合物在神经系统性疾病、炎症免疫疾病以及代谢性疾病研究中具有应用潜力。
TN4670	Norlichexanthone	Antibacterial; Parasite	Microbiology/Virology
	Norlichexanthone 具有治疗和/或预防生活方式相关疾病的潜力，例如 2 型糖尿病、代谢综合征、动脉粥样硬化和心血管疾病。它具有抗菌和抗疟活性，对枯草芽孢杆菌有很强的活性，IC50范围为1-5uM，对耐甲氧西林金黄色葡萄球菌的生长也有很强的抑制作用，IC50为20.95±1.56uM。
T36563	(E)-Guggulsterone	Others	Others
	Bile acids are essential for solubilization and transport of dietary lipids, are the major products of cholesterol catabolism, and are physiological ligands for farnesoid X receptor (FXR), a nuclear receptor that regulates genes involved in lipid metabolism.1They are also inherently cytotoxic, as physiological imbalance contributes to increased oxidative stress.2,3Bile acid-controlled signaling pathways are promising novel targets to treat such metabolic diseases as obesity, type II diabetes, hy...

天然产物

Cat.No: T3836

Target: MAPK, S6 Kinase

(R)-(-)-1,3-Butanediol

Cat.No: T19538

Target: Endogenous Metabolite

N-(3-Methoxybenzyl-(9z,12z)-octadecadienamide

Cat.No: TN1352

Synonym: 12顺-亚油酸酰胺,(9Z,12Z)-N-(3-Methoxybenzyl)octadeca-9,12-dienamide,n-3-methoxybenzyl-9z-12z-octadecadienamide,玛卡酰胺杂质10

Target: Drug Metabolite

4'-Methoxyflavanone

Cat.No: TN3050

Target: Others

Cat.No: T4A2456

Synonym: Gamabufagin,日本蟾蜍毒苷元

Target: COX

Caulophyllogenin

Cat.No: TN1475

Synonym: Segetalic acid

Target: IL Receptor, TNF, PPAR, Immunology/Inflammation related

Cat.No: T5623

Target: Others, Endogenous Metabolite

Aurantio-obtusin

Cat.No: T6S1559

Target: Others

3-Methyl-L-histidine

Cat.No: T8274

Target: Endogenous Metabolite

N-Acetyl-L-arginine

Cat.No: T8053

Synonym: N-Α-乙酰-L-精氨酸,Ac-Arg-OH

Target: Endogenous Metabolite

Cat.No: T19204

Target: Others

Erythronic acid potassium

Cat.No: T78466

Target: Endogenous Metabolite

Tridocosahexaenoylglycerol

Cat.No: TN7261

Synonym: TG-DHA,Meganol D

Target: Others

Norlichexanthone

Cat.No: TN4670

Target: Antibacterial, Parasite

(E)-Guggulsterone

Cat.No: T36563

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-00639	Alkaline Phosphatase (Germ type) /ALPG Protein, Rat, Recombinant (His) GCAP,ALP-1,Alkaline Phosphatase,ALPPL2,PLAP-like,ALPPL,ALPG,...	Rat	HEK293 Cells
	Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Rat, Recombinant (His) is expressed in HEK293...
TMPY-01460	ABHD4 Protein, Human, Recombinant (His) abhydrolase domain containing 4,ABH4	Human	Baculovirus Insect Cells
	Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4) , or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain containing (ABHD) gene was a small group belongs to alpha/beta hydrolase superfamily. Known members of this group are all found to be involved in important biochemical processes and related to various diseases. The alpha/beta-hydrolase 4 (ABH4) is a lysophospholipase/phospholipa...
TMPK-00803	Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His) ALPG,ALPPL,Alkaline phosphatase, placental-like,Alkaline Pho...	Human	HEK293 Cells
	Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His) is expressed in HEK2...
TMPK-00796	Alkaline phosphatase (Intestinal type) /ALPI Protein, Human, Recombinant (His & Flag) FLJ40094,ALPI,APTNAP,EC 3.1.3.1,AP-TNAP,IAP,TNAP,HOPS,FLJ930...	Human	HEK293 Cells
	Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline phosphatase (Intestinal type) /ALPI Protein, Human, Recombinant (His & Flag) is expr...
TMPK-01326	Alkaline Phosphatase (Placental type) /ALPP Protein, Cynomolgus, Recombinant (His) Alkaline phosphatase,PLAP,PLAP-1,ALPP	Cynomolgus	HEK293 Cells
	Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Placental type) /ALPP Protein, Cynomolgus, Recombinant (His) is express...
TMPK-00801	Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His & Avi), Biotinylated ALPPL2,PLAP-like,GCAP,ALPG,Alkaline phosphatase, placental-l...	Human	HEK293 Cells
	Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His & Avi), Biotinylated ...
TMPK-00802	Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (hFc) GCAP,ALPPL,Alkaline phosphatase, placental-like,Alkaline Pho...	Human	HEK293 Cells
	Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (hFc) is expressed in HEK2...
TMPK-00684	Alkaline phosphatase (Intestinal type) /ALPI Protein, Mouse, Recombinant (His) IAP,TNSALP,APTNAP,FLJ40094,AP-TNAP,MGC161443,TNAP,Akp2,HOPS,...	Mouse	HEK293 Cells
	Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline phosphatase (Intestinal type) /ALPI Protein, Mouse, Recombinant (His) is expressed i...
TMPK-00855	Alkaline Phosphatase (Germ type) /ALPG Protein, Mouse, Recombinant (His) Alkaline Phosphatase,Alppl2,Akp5,Alpg,Alkaline phosphatase, ...	Mouse	HEK293 Cells
	Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Mouse, Recombinant (His) is expressed in HEK2...
TMPK-00804	Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (mFc) GCAP,Alkaline Phosphatase,PLAP-like,Alkaline phosphatase, pl...	Human	HEK293 Cells
	Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (mFc) is expressed in HEK2...
TMPY-04554	JNK1 Protein, Human, Recombinant (GST) PRKM8,JNK,JNK-46,JNK21B1/2,JNK1A2,mitogen-activated protein ...	Human	Baculovirus Insect Cells
	Mitogen-activated protein kinase 8 (MAPK8), also known as JNK1, is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. The protein kinases JNK1 has been found to serve as critical molecular links between obesity, metabolic inflammation, and disorders of glucose homeostasis. It is critically involved in ...
TMPY-03985	Adenosine Deaminase Protein, Human, Recombinant (His) ADA1,adenosine deaminase,ADA	Human	Baculovirus Insect Cells
	Adenosine Desaminase (ADA) deficiency, is a purine metabolic disorder that cause severe combined immunodeficiency (SCID) due to the accumulation of toxic metabolites that primarily affects development, differentiation and function of T and B lymphocytes. Adenosine deaminase is a polymorphic enzyme that has an important role in immune functions and in the regulation of intracellular and extracellular concentrations of adenosine and adenosine receptor activity. ADA activity might be considered as...
TMPY-05029	INHBE Protein, Human, Recombinant (hFc) inhibin beta E,inhibin β E	Human	HEK293 Cells
	INHBE (Inhibin Subunit Beta E) is a Protein Coding gene. This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate an inhibin beta subunit. INHBE was identified as a novel putative hepatokine with hepatic gene expression that positively correlated with insulin resistance and body mass index in humans. The quantitative real time-PCR analysis also showed an increase in INHBE gene expressi...
TMPY-02622	Aldolase B Protein, Human, Recombinant (GST) aldolase B, fructose-bisphosphate,ALDO2,ALDB	Human	E. coli
	The aldolase family members involved in metabolism and glycolysis are present in three isoforms: ALDOA, ALDOB, and ALDOC. Aldolases are differentially expressed in human tissues, and aberrant expression has been observed in several human diseases and cancer types. Via GATA6, metastatic cells in the liver upregulate the enzyme aldolase B (ALDOB), which enhances fructose metabolism and provides fuel for major pathways of central carbon metabolism during tumor cell proliferation. Targeting ALDOB or...

重组蛋白

Alkaline Phosphatase (Germ type) /ALPG Protein, Rat, Recombinant (His)

Cat.No: TMPK-00639

Species: Rat

Expression System: HEK293 Cells

ABHD4 Protein, Human, Recombinant (His)

Cat.No: TMPY-01460

Species: Human

Expression System: Baculovirus Insect Cells

Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His)

Cat.No: TMPK-00803

Species: Human

Expression System: HEK293 Cells

Alkaline phosphatase (Intestinal type) /ALPI Protein, Human, Recombinant (His & Flag)

Cat.No: TMPK-00796

Species: Human

Expression System: HEK293 Cells

Alkaline Phosphatase (Placental type) /ALPP Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01326

Species: Cynomolgus

Expression System: HEK293 Cells

Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00801

Species: Human

Expression System: HEK293 Cells

Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00802

Species: Human

Expression System: HEK293 Cells

Alkaline phosphatase (Intestinal type) /ALPI Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00684

Species: Mouse

Expression System: HEK293 Cells

Alkaline Phosphatase (Germ type) /ALPG Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00855

Species: Mouse

Expression System: HEK293 Cells

Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (mFc)

Cat.No: TMPK-00804

Species: Human

Expression System: HEK293 Cells

JNK1 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04554

Species: Human

Expression System: Baculovirus Insect Cells

Adenosine Deaminase Protein, Human, Recombinant (His)

Cat.No: TMPY-03985

Species: Human

Expression System: Baculovirus Insect Cells

INHBE Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05029

Species: Human

Expression System: HEK293 Cells

Aldolase B Protein, Human, Recombinant (GST)

Cat.No: TMPY-02622

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
T19261	D-Glucose-13C6 D-(+)-Glucose-13C6,Glucose-13C6,Dextrose-13C6	Endogenous Metabolite	Metabolism
	D-Glucose-13C6 (Dextrose-13C6) 是一种 D-Glucose 的同位素标记物，可作为代谢示踪剂，可用于研究机体代谢相关疾病和部分物质的代谢过程。

同位素标记化合物

Cat.No: T19261

Synonym: D-(+)-Glucose-13C6,Glucose-13C6,Dextrose-13C6

Target: Endogenous Metabolite

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