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Targets Recommended: MAPK p38 MAPK Microtubule Associated

150

抑制剂 & 化合物

18

天然产物

2

化合物库

89

重组蛋白

3

同位素标记化合物

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Cat. No.	Product Name
L1400	MAPK 抑制剂库		365 compounds
	365 种与MAPK 信号通路相关的生物活性小分子化合物的特有集合，可用于高通量筛选和高内涵筛选；
L7840	高溶解性卤化片段化合物库		796 compounds
	高溶解性卤化片段库包含796 个卤化片段化合物。

化合物库

MAPK 抑制剂库

Cat.No: L1400

Compounds: 365

高溶解性卤化片段化合物库

Cat.No: L7840

Compounds: 796

Cat. No.	Product Name	Target	Signaling Pathways
T9504	MAP4343	Microtubule Associated	Cytoskeletal Signaling
	MAP4343 是孕烯醇酮的 3-甲基醚衍生物。它在体外与微管相关蛋白 2 (MAP2) 结合并刺激微管蛋白聚合，从而增强神经突延伸和保护神经元免受神经毒剂的侵害。
T67944	p38 MAP Kinase Inhibitor Ⅵ	p38 MAPK	MAPK
	p38 MAP Kinase Inhibitor Ⅵ是一种有效的p38 MAP Kinase 抑制剂，具有抗炎活性。
T11942	MAP4K4-IN-3 Compound 17	MAPK	MAPK
	MAP4K4-IN-3 (Compound 17) 是 MAP4K4选择性抑制剂，在激酶实验中 IC50为 14.9 nM，在细胞实验中 IC50为 470 nM。具有抗糖尿病作用。
TP2269	MAP kinase fragment [Multiple species]	Others	Others
	This Mitogen-activated protein kinase (MAP kinase) fragment has a peptide sequence of Lys-Tyr-Ile-His-Ser-Ala-Asn-Val-Leu. The MAP kinases are serine/threonine-specific protein kinases belonging to the CMGC (CDK/MAPK/GSK3/CLK) kinase group.
T36011	p38 MAP Kinase Inhibitor IV p38 MAPK Inhibitor IV	Others	Others
	p38 MAPK inhibitor IV is an ATP-competitive inhibitor of p38 MAP kinases with IC50 values of 0.13, 0.55, 5.47, and 8.63 μM for p38α, p38β, p38x, and p38δ, respectively, in vitro.[1] It also inhibits LPS-induced TNF-α and IL-1β cytokine production (IC50s = 22 and 44 nM, respectively) in human peripheral blood mononuclear cells.
T60011	HS220	MAPK	MAPK
	HS220 是 TAK1 抑制剂，TAK1 在炎症和细胞存活的信号通路中起关键作用。
T22961	MAP4	Others	Others
	metabotropic glutamate receptor modulator
T5190	GS-444217 GS 444217,GS444217	Apoptosis; ASK; MAPK	Apoptosis; MAPK
	GS-444217 是一种可口服的选择性 ATP 竞争性凋亡信号调节激酶 1 抑制剂，IC50为 2.87 nM。
T5643	NG25	MAPK	MAPK
	NG25 是TAK1(IC50:149 nM)和MAP4K2(IC50:21.7 nM)的双抑制剂。
T3101	NQDI-1 NQDI1,NQDI 1	Apoptosis; ASK; MAPK	Apoptosis; MAPK
	NQDI-1 (NQDI 1) 是一种凋亡信号调节激酶 1 抑制剂，Ki 为 500 nM，IC50为 3 μM。
T3350	Selonsertib GS-4997	Apoptosis; ASK; MAPK	Apoptosis; MAPK
	Selonsertib (GS-4997) 是一种选择性的，具有生物口服可利用的凋亡信号调节激酶1 抑制剂，pIC50为 8.3。它具有潜在的抗炎、抗肿瘤和抗纤维化活性。
T9377	ASK1-IN-2	Apoptosis; ASK; MAPK	Apoptosis; MAPK
	ASK1-IN-2 是一种口服有活性的凋亡信号调节激酶 1 抑制剂(IC50:32.8 nM)。它可用于研究溃疡性结肠炎。
T15250	ETC-206	MNK	MAPK
	ETC-206 是选择性 MNK1和 MNK2抑制剂，IC50分别为 64 和 86 nM。
T13099	TC ASK 10	ASK; MAPK	Apoptosis; MAPK
	TC ASK 10 是选择性的，口服有效的细胞凋亡信号调节激酶 1 抑制剂，IC50为 14 nM。它对其他代表性激酶的抑制活性低于 50％，除 ASK2之外 (IC50为 0.51 μM)。
T3468	Tomivosertib eFT508	MNK; PD-1/PD-L1	Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation; MAPK
	Tomivosertib (eFT508) 是一种具有口服活性的MNK1和MNK2高选择性抑制剂，IC50值均为 1-2 nM。它可降低肿瘤细胞中eIF4E 的磷酸化水平 (位点为 Ser209，IC50=2-16 nM)，下调PD-L1蛋白的平均含量。
T3707	GNE-3511 GNE3511	DNA Alkylation; MAPK	DNA Damage/DNA Repair; MAPK
	GNE-3511是双亮氨酸拉链激酶 (DLK)抑制剂(Ki:0.5 nM)。
T16987	TAO Kinase inhibitor 1	Others; MAPK	MAPK; Others
	TAO Kinase inhibitor 1 是一种ATP 竞争性的thousand-and-one amino acid kinases (TAOK)选择性抑制剂，对于 TAOK1 和 TAOK2 的IC50s 分别为 11 nM 和 15 nM。它能够延迟有丝分裂以及诱导有丝分裂细胞死亡。
T4264	Takinib EDHS-206	Apoptosis; MAPK	Apoptosis; MAPK
	Takinib (EDHS-206) 是一种TAK1自磷酸化的抑制剂，也是恶性疟原虫蛋白激酶 9 抑制剂，在 ATP 结合口袋内非竞争性结合。它诱导 TNF-α 刺激的细胞凋亡，可研究类风湿关节炎和转移性乳腺癌。
T14988	CMPD1	MAPK	MAPK
	CMPD1 是非 ATP 竞争性 p38 MAPK 介导的 MK2磷酸化选择性抑制剂(Ki:330 nM)。
T4424	SLV-2436 SEL-201,SLV 2436,SEL201-88	MNK	MAPK
	SLV-2436 (SEL201-88) 是一种高效且 ATP 竞争性的MNK1和MNK2抑制剂，IC50分别为 10.8 和 5.4 nM。
T6440	CGP 57380 N3-(4-氟苯基)-1H-吡唑并[3,4-D]嘧啶-3,4-二胺,MNK1 Inhibitor	Apoptosis; MNK	Apoptosis; MAPK
	CGP 57380 (MNK1 Inhibitor) 是细胞渗透的吡唑-嘧啶类化合物，是一种具有选择性的Mnk1抑制剂，IC50值为 2.2 μM。
T64001	MAP855	Others	Others
	MAP855 是一种高效的、选择性的、口服具有活力的具、 ATP 竞争性的 MEK1/2 激酶抑制剂，对 MEK1 ERK2 cascade 的 IC50 值为 3 nM，pERKEC50 值为 5 nM。MAP855 对野生型和突变型 MEK1/2 表现出同等的抑制效果。
T16501	PF-3644022	p38 MAPK; Serine Protease; MAPK	MAPK; Proteases/Proteasome
	PF-3644022 是可口服的，具有 ATP 竞争性的MAPKAPK2 (MK2)选择性抑制剂，IC50为 5.2 nM，Ki 为 3 nM。它有效抑制 TNFα 的产生并具有抗炎作用，还抑制 MK3 和 p38 调节/激活激酶，IC50分别为 53 和 5.0 nM。
T12058	MK2-IN-3 hydrate MK-2 Inhibitor III	ERK; MAPK; MNK	MAPK
	MK2-IN-3 hydrate (MK-2 Inhibitor III) 是一种口服有活性的、ATP 竞争性的MAPKAP-K2 (MK-2)选择性抑制剂(IC50:0.85 nM)。
T9034	MK2-IN-3 MK2 Inhibitor III	MAPK	MAPK
	MK2-IN-3 (MK2 Inhibitor III) 是选择性的 MAPKAP-K2 (MK-2)抑制剂(IC50:8.5 nM)，能够抑制 U937 细胞及体内 TNFα 的生成。
T4442	MK2-IN-1 hydrochloride MK2 Inhibitor,MK 25	MAPK	MAPK
	MK2-IN-1 hydrochloride (MK 25) 是一种高效的选择性 MAPKAPK2(MK2)激酶抑制剂，其 IC50值为0.11uM。
T69894	MAP3K14-IN-173	Others	Others
	MAP3K14-IN-173 is a potent MAP3K14 kinase inhibitor.
T79794	TNIK&MAP4K4-IN-1	Others	Others
	TNIK&MAP4K4-IN-1（化合物A-39）作为TNIK和MAP4K4/HGK的双效抑制剂，在LX-2人肝星状细胞中，其IC50为1.29 nM和<10 nM。该化合物适用于癌症和纤维化治疗。
T1667	Tandutinib MLN518,CT53518,NSC726292,坦度替尼	Apoptosis; FLT; CSF-1R; PDGFR; Src; c-Kit	Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
	Tandutinib (CT53518) 是一种选择性 FLT3抑制剂，其 IC50为 0.22 μM。它还抑制c-Kit 和PDGFR，其IC50分别为 0.17 μM 和 0.20 μM。它可穿透血脑屏障，用于急性骨髓性白血病。
T7196	HG-10-102-01 [4-[[5-氯-4-(甲基氨基)-2-嘧啶基]氨基]-3-甲氧基苯基]-4-吗啉基甲酮	LRRK2	Autophagy
	HG-10-102-01 是富含亮氨酸重复激酶 2 和突变型G2019S 抑制剂，IC50分别为20.3 nM 和3.2 nM。
T36010	p38 MAPK Inhibitor	p38 MAPK	MAPK
	p38 MAPK Inhibitor 是p38 MAPK 激酶的有效抑制剂（IC50＝ 35 nM）。p38 MAPK Inhibitor 抑制癌基因RAS 诱导的衰老。
T7367	Acumapimod BCT-197	p38 MAPK; Autophagy	Autophagy; MAPK
	Acumapimod (BCT-197) 是一种有口服活性的p38 MAP 激酶抑制剂，IC50值小于1 μM。
T77751	Imaprelimab PRX-003	Others	Others
	Imaprelimab (PRX-003) 是一种人源化抗黑素瘤细胞粘附分子 (MCAM) 的 IgG1κ 单克隆抗体。Imaprelimab 具有抗肿瘤活性，可用于研究炎症、肿瘤、银屑病。
T2664	Timapiprant OC000459	GPR; Prostaglandin Receptor	Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation
	Timapiprant (OC000459) 是一种有效的选择性 D 前列腺素受体 2(DP2) 拮抗剂，IC50为 13 nM。它抑制肥大细胞激活 Th2 淋巴细胞和嗜酸性粒细胞，有效地置换来自人重组 DP2、大鼠重组 DP2 和人天然 DP2 的 [3H] PGD2。
T38570	DMAPP triammonium Dimethylallyl diphosphate triammonium,Dimethylallyl Pyrophosphate triammonium salt	Others	Others
	DMAPP triammonium (Dimethylallyl diphosphate triammonium) 是一种异戊二烯类化合物的前提物质之一，参与甲羟戊酸 (MVA) 途径，可用于研究与代谢相关的疾病。
T22724	Dimaprit dihydrochloride	NOS; NO Synthase; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Dimaprit dihydrochloride 是组胺H2受体的一种选择性激动剂，可刺激胃酸的分泌。它还抑制nNOS，IC50值为 49 μM。
T63067	Emprumapimod PF-07265803,ARRY-371797	p38 MAPK	MAPK
	Emprumapimod (PF-07265803) 是一种具有口服活性和特异性的丝裂原活化蛋白激酶 p38α MAPK 抑制剂，抑制 LPS 诱导产生的 IL-6 ，可用于研究 LMNA 基因引起的扩张型心肌病。
T40622	Mapenterol hydrochloride	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Mapenterol hydrochloride 是 β2 肾上腺素受体激动剂。
T38796L	MBP MAPK Substrate acetate MBP MAPK Substrate acetate(138028-00-9 free base)	MAPK	MAPK
	MBP MAPK Substrate acetate 可用作 MAPK 的外源性底物。
T6277	Doramapimod BIRB 796,达马莫德,度马莫德	Raf; p38 MAPK; Autophagy	Autophagy; MAPK
	Doramapimod (BIRB 796) 是一种具有口服活性的p38 MAPK 抑制剂，Kd 值为0.1nM。它也抑制B-Raf 和 Abl，IC50分别为 83 nM 和 14.6 μM。
T16682	Pumaprazole BY-841,普马拉唑	Proton pump	Membrane transporter/Ion channel
	Pumaprazole (BY-841) 是一种有效的、可逆的质子泵拮抗剂。
T6927	Pamapimod R1503,帕吡莫德,Ro4402257	p38 MAPK; Autophagy	Autophagy; MAPK
	Pamapimod (R1503) 是一种新型的选择性 p38 丝裂原活化蛋白激酶抑制剂，对于p38α和p38β的IC50分别为 14 nM 和 480 nM，Ki 分别为 1.3 nM 和 120 nM，对 p38δ 或 p38γ 亚型没有活性，可研究类风湿关节炎和其他自身免疫性疾病。
T12347	p38-α MAPK-IN-1	p38 MAPK; Autophagy	Autophagy; MAPK
	p38-α MAPK-IN-1 是一种 MAPK14 (p38-α) 抑制剂，在 EFC 置换试验和 HTRF 试验中 IC50 分别为 2300 nM 和 5500 nM。
T6089	Neflamapimod VX-745	p38 MAPK; Autophagy	Autophagy; MAPK
	Neflamapimod (VX-745) 是一种可穿过血脑屏障的，高选择性的p38α抑制剂，对 p38α 的IC50值为 10 nM，p38β 的IC50值为 220 nM。它对 p38β 的特异性高 22 倍，具有抗炎活性。
T77780	Zamaporvint RXC004	Others	Others
	Zamaporvint (RXC004) 是一种具有选择性、口服活性和有效性的 Wnt 途径抑制剂，作用于膜结合脂肪酰转移酶 Porcupine，阻断 Wnt 配体棕榈酰化、分泌及通路活化。Zamaporvint 在多种癌细胞系中显示出抗肿瘤和抗增殖活性。
T1764	Adezmapimod PB 203580,4-(4-氟苯基)-2-(4-甲基亚磺酰基苯基)-5-(4-吡啶基)-1H-咪唑,RWJ 64809,SB203580	Mitophagy; p38 MAPK; Autophagy	Autophagy; MAPK
	Adezmapimod (SB 203580) 是一种 p38 MAPK 抑制剂 (IC50=0.3-0.5 μM)，具有选择性和 ATP 竞争性。Adezmapimod 具有自噬和线粒体自噬的激活活性。Adezmapimod 显示出比 PKB、LCK 和 GSK-3β 高 100 倍以上的选择性。
T35593	Semapimod tetrahydrochloride CPSI-2364 tetrahydrochloride	TLR; MAPK	Immunology/Inflammation; MAPK
	Semapimod tetrahydrochloride (CPSI-2364 tetrahydrochloride) 是一种合成鸟腙丝裂原活化蛋白激酶阻滞剂,也是促炎细胞因子生成抑制剂，干扰巨噬细胞和小胶质细胞功能。Semapimod tetrahydrochloride 可抑制 TLR4 信号传导，抑制 TNF-α、IL-1β 和 IL-6，可用于研究克罗恩病和其他炎症。
T2277	Losmapimod GSK-AHAB,GW856553X,6-[5-(环丙基氨基甲酰基)-3-氟-2-甲基苯基]-N-(2,2-二甲基丙基)吡啶-3-甲酰胺,GW856553,洛批莫德,SB856553	p38 MAPK; Autophagy	Autophagy; MAPK
	Losmapimod (GSK-AHAB) 是一种可口服的特异性 p38 MAPK 抑制剂，抑制 p38α 和 p38β 的 pKi 值分别为 8.1 和 7.6。
T2675	Bentamapimod AS 602801	JNK	MAPK
	Bentamapimod (AS 602801) 是一种ATP 竞争性的JNK 抑制剂，对JNK1、JNK2和JNK3的IC50分别为 80、90 和 230 nM。
T11943	MAPK13-IN-1	p38 MAPK	MAPK
	MAPK13-IN-1 是一种有效的 MAPK13 (p38δ) 抑制剂（IC50：620 nM）。

化合物

Cat.No: T9504

Target: Microtubule Associated

p38 MAP Kinase Inhibitor Ⅵ

Cat.No: T67944

Target: p38 MAPK

Cat.No: T11942

Synonym: Compound 17

Target: MAPK

MAP kinase fragment [Multiple species]

Cat.No: TP2269

Target: Others

p38 MAP Kinase Inhibitor IV

Cat.No: T36011

Synonym: p38 MAPK Inhibitor IV

Target: Others

Cat.No: T60011

Target: MAPK

Cat.No: T22961

Target: Others

Cat.No: T5190

Synonym: GS 444217,GS444217

Target: Apoptosis, ASK, MAPK

Cat.No: T5643

Target: MAPK

Cat.No: T3101

Synonym: NQDI1,NQDI 1

Target: Apoptosis, ASK, MAPK

Cat.No: T3350

Synonym: GS-4997

Target: Apoptosis, ASK, MAPK

Cat.No: T9377

Target: Apoptosis, ASK, MAPK

Cat.No: T15250

Target: MNK

Cat.No: T13099

Target: ASK, MAPK

Cat.No: T3468

Synonym: eFT508

Target: MNK, PD-1/PD-L1

Cat.No: T3707

Synonym: GNE3511

Target: DNA Alkylation, MAPK

TAO Kinase inhibitor 1

Cat.No: T16987

Target: Others, MAPK

Cat.No: T4264

Synonym: EDHS-206

Target: Apoptosis, MAPK

Cat.No: T14988

Target: MAPK

Cat.No: T4424

Synonym: SEL-201,SLV 2436,SEL201-88

Target: MNK

Cat.No: T6440

Synonym: N3-(4-氟苯基)-1H-吡唑并[3,4-D]嘧啶-3,4-二胺,MNK1 Inhibitor

Target: Apoptosis, MNK

Cat.No: T64001

Target: Others

Cat.No: T16501

Target: p38 MAPK, Serine Protease, MAPK

MK2-IN-3 hydrate

Cat.No: T12058

Synonym: MK-2 Inhibitor III

Target: ERK, MAPK, MNK

Cat.No: T9034

Synonym: MK2 Inhibitor III

Target: MAPK

MK2-IN-1 hydrochloride

Cat.No: T4442

Synonym: MK2 Inhibitor,MK 25

Target: MAPK

MAP3K14-IN-173

Cat.No: T69894

Target: Others

TNIK&MAP4K4-IN-1

Cat.No: T79794

Target: Others

Cat.No: T1667

Synonym: MLN518,CT53518,NSC726292,坦度替尼

Target: Apoptosis, FLT, CSF-1R, PDGFR, Src, c-Kit

Cat.No: T7196

Synonym: [4-[[5-氯-4-(甲基氨基)-2-嘧啶基]氨基]-3-甲氧基苯基]-4-吗啉基甲酮

Target: LRRK2

p38 MAPK Inhibitor

Cat.No: T36010

Target: p38 MAPK

Cat.No: T7367

Synonym: BCT-197

Target: p38 MAPK, Autophagy

Cat.No: T77751

Synonym: PRX-003

Target: Others

Cat.No: T2664

Synonym: OC000459

Target: GPR, Prostaglandin Receptor

DMAPP triammonium

Cat.No: T38570

Synonym: Dimethylallyl diphosphate triammonium,Dimethylallyl Pyrophosphate triammonium salt

Target: Others

Dimaprit dihydrochloride

Cat.No: T22724

Target: NOS, NO Synthase, Histamine Receptor

Cat.No: T63067

Synonym: PF-07265803,ARRY-371797

Target: p38 MAPK

Mapenterol hydrochloride

Cat.No: T40622

Target: Adrenergic Receptor

MBP MAPK Substrate acetate

Cat.No: T38796L

Synonym: MBP MAPK Substrate acetate(138028-00-9 free base)

Target: MAPK

Cat.No: T6277

Synonym: BIRB 796,达马莫德,度马莫德

Target: Raf, p38 MAPK, Autophagy

Cat.No: T16682

Synonym: BY-841,普马拉唑

Target: Proton pump

Cat.No: T6927

Synonym: R1503,帕吡莫德,Ro4402257

Target: p38 MAPK, Autophagy

p38-α MAPK-IN-1

Cat.No: T12347

Target: p38 MAPK, Autophagy

Cat.No: T6089

Synonym: VX-745

Target: p38 MAPK, Autophagy

Cat.No: T77780

Synonym: RXC004

Target: Others

Cat.No: T1764

Synonym: PB 203580,4-(4-氟苯基)-2-(4-甲基亚磺酰基苯基)-5-(4-吡啶基)-1H-咪唑,RWJ 64809,SB203580

Target: Mitophagy, p38 MAPK, Autophagy

Semapimod tetrahydrochloride

Cat.No: T35593

Synonym: CPSI-2364 tetrahydrochloride

Target: TLR, MAPK

Cat.No: T2277

Synonym: GSK-AHAB,GW856553X,6-[5-(环丙基氨基甲酰基)-3-氟-2-甲基苯基]-N-(2,2-二甲基丙基)吡啶-3-甲酰胺,GW856553,洛批莫德,SB856553

Target: p38 MAPK, Autophagy

Cat.No: T2675

Synonym: AS 602801

Target: JNK

Cat.No: T11943

Target: p38 MAPK

Cat. No.	Product Name	Target	Signaling Pathways
T14055	5Z-7-Oxozeaenol FR148083,L783279,LL-Z 1640-2	VEGFR; FLT; MEK; MAPK; PDGFR; Antibiotic; Src	Angiogenesis; MAPK; Microbiology/Virology; Tyrosine Kinase/Adaptors
	5Z-7-Oxozeaenol (FR148083) 是一种天然抗原生动物抑制剂，不可逆的选择性抑制 TAK1和 VEGF-R2，IC50值分别为 8 nM 和 52 nM。
T11060	DMAPT Dimethylamino Parthenolide	NF-κB	NF-κB
	DMAPT (Dimethylamino Parthenolide) 是一种具有口服活性的NF-κB 抑制剂，是一种 Parthenolide (PTL) 的类似物，对原发性急性髓性白血病细胞的LD50值为1.7 μM。具有潜在的抗肿瘤和抗转移作用。
T36303	Psammaplin A	Others	Others
	Psammaplin A, a marine metabolite, functions as a robust inhibitor of HDAC and DNA methyltransferases, displaying notable potency and selectivity as a DAC1 inhibitor, with an IC50 value of 0.9 nM. It exhibits antimicrobial effects against Gram-positive bacteria and inhibits both DNA synthesis and DNA gyrase activity, also demonstrating antitumor activity[1][2].
TN5795	Chimaphilin 梅笠草素,2,7-Dimethyl-1,4-naphthoquinone
	Chimaphilin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5795，CAS号为 482-70-2。
T3S0462	Rehmapicroside	Others	Others
	Rehmapicroside是一种天然产物，属于玄参科地黄属，其产品编号为 T3S0462，CAS号为 104056-82-8。Rehmapicroside可用作对照参考。
T80259	PMAP-23	Others	Others
	PMAP-23为具有生物活性的抗菌肽(AMP)，源自猪骨髓。
T40454	DMAPP Dimethylallyl diphosphate	Others	Others
	DMAPP, also known as Dimethylallyl pyrophosphate, is an isoprenoid precursor found in all life forms. It serves as an isomer of isopentenyl pyrophosphate (IPP).
TN2336	Rehmapicrogenin	Nrf2	Immunology/Inflammation
	Rehmapicrogenin 调节 Nrf2/ARE 信号通路。Nrf2/ARE 信号通路是氧化应激的重要途径。
TN1505	Clemaphenol A	Others	Others
	Clemaphenol A is a natural product from Cynanchum auriculatum.
TN5796	3-Hydroxychimaphilin
	3-Hydroxychimaphilin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5796，CAS号为 33253-99-5。
TN2354	Methylnissolin 3-Hydroxy-9,10-dimethoxyptercarpan,黄芪紫檀烷,黄芪紫檀烷苷,3-羟基-9,10-二甲氧基紫檀烷	ERK; PDGFR	Angiogenesis; MAPK; Tyrosine Kinase/Adaptors
	Methylnissolin 是从黄芪中分离的一种天然产物，可抑制血小板衍生生长因子 (PDGF)-BB 诱导的细胞增殖，IC50为 10 μM。。它通过抑制ERK1/2MAP 激酶级联反应抑制 PDGF-BB 诱导的血管平滑肌细胞增殖。它还抑制 PDGF-BB 诱导的细胞外信号调节激酶 1/2 (ERIC1/2) 丝裂原活化蛋白 (MAP) 激酶的磷酸化，具有抗菌和抗癌作用。
T7030	anemarsaponin B 知母皂苷B,知母皂苷 B	p38 MAPK; NF-κB; MEK; COX; NO Synthase	Immunology/Inflammation; MAPK; Neuroscience; NF-κB
	Anemarsaponin B 是一种甾体皂苷，可降低iNOS 和COX-2的蛋白和 mRNA 水平，减少促炎细胞因子的表达和产生。它通过阻断 IκBα 的磷酸化来抑制NF-κB 的 p65 亚基的核转位，还抑制 MAP 激酶激酶 3/6 (MKK3/6) 和混合谱系激酶 3 的磷酸化。
T2787	Picroside I 6'-Cinnamoylcatalpol,胡黄连苦苷I	MMP; STAT	JAK/STAT signaling; Proteases/Proteasome; Stem Cells
	Picroside I (6'-Cinnamoylcatalpol) 是胡黄连的一种天然产物，是有肝脏保护作用的代谢成分，可用于哮喘研究，有减轻炎症作用，还下调 pSTAT6 和 GATA3 表达。
T6S1740	Nardosinone 苷松新酮,甘松新酮	Others	Others
	Nardosinone 是一个 dbcAMP 和 staurosporine 的神经生成作用增强剂，分离自Nardostachys chinensis 中。Nardosinone 可能成为一种有用的药理学工具，不仅可用于研究神经生长因子 (NGF) 的作用机理，而且可用于研究神经毒性物质的作用机理。
TN1338	7Beta-Hydroxycholesterol	LDL; Calcium Channel; MAPK	MAPK; Membrane transporter/Ion channel; Metabolism
	7beta-Hydroxycholesterol, a major cytotoxin in oxidized LDL, induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells.
TN2039	Panaxydol	cAMP; p38 MAPK; JNK	GPCR/G Protein; MAPK
	Panaxydol has anti-cancer activity, can inhibit the growth and apoptosis of cancer cells, the signaling mechanisms involve a [Ca(2+)](i) increase, JNK and p38 MAPK activation, cAMP, MAP kinase and ROS generation through NADPH oxidase and mitochondria.
T10910	Cycloartenol	Others	Others
	Cyclopentanol is a plant sterol compound and one of the key precursors for biosynthesis of various sterol compounds. Cycloartenol inhibits the migration of glioma cells and inhibits the phosphorylation of p38 MAP kinase. Cycloenol has various pharmacologi
TN5153	Torilin	MMP; ERK; IκB/IKK; p38 MAPK; NF-κB; Tyrosinase; Reductase; DNA/RNA Synthesis; JNK	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Endocrinology/Hormones; MAPK; Metabolism; NF-κB; Proteases/Proteasome
	Torilin 是一种睾酮5α还原酶抑制剂，它（IC50=31.7+/-4.23μM）对5α还原酶的抑制作用强于α-亚麻酸（IC50=160.3+/-24.62μM），但弱于非那雄胺（IC50=0.38+/-0.06μM）。Torilin 具有免疫调节、肝脏保护和抗炎特性，它通过限制 TAK1介导的 MAP 激酶和 NF-βB 活化来抑制炎症，它可以减轻关节炎的严重程度，改变 dLN 或关节中的白细胞活化，并恢复血清和脾细胞细胞因子失衡。托利林抑制α-黑素细胞刺激激素激活的 B16黑色素瘤细胞中的黑色素生成，IC（50）值为25μM。Torilin 对枯草芽孢杆菌 ATCC 6633孢子和营养细胞表现出优异的抗菌活性。Torilin 在体内和体外都具有强大的抗血管生成活性，它可能通过抑制肿瘤侵袭来抑制肿瘤发生，逆转癌细胞的多药耐药性，它可以增强阿霉素、长春碱、紫杉醇和秋水仙碱对多药耐药 KB-V1和 MCF7/ADR 细胞的细胞毒性。

天然产物

5Z-7-Oxozeaenol

Cat.No: T14055

Synonym: FR148083,L783279,LL-Z 1640-2

Target: VEGFR, FLT, MEK, MAPK, PDGFR, Antibiotic, Src

Cat.No: T11060

Synonym: Dimethylamino Parthenolide

Target: NF-κB

Cat.No: T36303

Target: Others

Cat.No: TN5795

Synonym: 梅笠草素,2,7-Dimethyl-1,4-naphthoquinone

Cat.No: T3S0462

Target: Others

Cat.No: T80259

Target: Others

Cat.No: T40454

Synonym: Dimethylallyl diphosphate

Target: Others

Rehmapicrogenin

Cat.No: TN2336

Target: Nrf2

Cat.No: TN1505

Target: Others

3-Hydroxychimaphilin

Cat.No: TN5796

Cat.No: TN2354

Synonym: 3-Hydroxy-9,10-dimethoxyptercarpan,黄芪紫檀烷,黄芪紫檀烷苷,3-羟基-9,10-二甲氧基紫檀烷

Target: ERK, PDGFR

anemarsaponin B

Cat.No: T7030

Synonym: 知母皂苷B,知母皂苷 B

Target: p38 MAPK, NF-κB, MEK, COX, NO Synthase

Cat.No: T2787

Synonym: 6'-Cinnamoylcatalpol,胡黄连苦苷I

Target: MMP, STAT

Cat.No: T6S1740

Synonym: 苷松新酮,甘松新酮

Target: Others

7Beta-Hydroxycholesterol

Cat.No: TN1338

Target: LDL, Calcium Channel, MAPK

Cat.No: TN2039

Target: cAMP, p38 MAPK, JNK

Cat.No: T10910

Target: Others

Cat.No: TN5153

Target: MMP, ERK, IκB/IKK, p38 MAPK, NF-κB, Tyrosinase, Reductase, DNA/RNA Synthesis, JNK

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01344	MAP1D Protein, Human, Recombinant (His) MetAP 1D,Metap1l,MAP 1D,methionyl aminopeptidase ty...	Human	Baculovirus Insect Cells
	Methionine aminopeptidase 1D, also known as MAP1D, is a member of the peptidase M24A family. N-terminal methionine removal is an important cellular process required for proper biological activity, subcellular localization, and eventual degradation of many proteins. The enzymes that catalyze this reaction are called Methionine aminopeptidases (MAPs). MAP1D is overexpressed in colon cancer cell lines and colon tumors as compared to normal tissues (at protein level). Downregulation of MAP1D express...
TMPH-00654	Methionine aminopeptidase Protein, E. coli, Recombinant (His & SUMO) Methionine aminopeptidase,map,Peptidase M	E. coli	E. coli
	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.
TMPH-03029	MetAP Protein, Mycoplasma pneumoniae, Recombinant (His & SUMO) Peptidase M,Methionine aminopeptidase,map	Mycoplasma pneumoniae	E. coli
	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.
TMPH-03072	MPK5 Protein, Japonica rice, Recombinant (His & Myc) MPK5,Multiple stress-responsive MAP kinase 2,MA...	Rice	E. coli
	MPK5 Protein, Japonica rice, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 48.0 kDa and the accession number is Q10N20.
TMPH-03018	MeTAP1 Protein, Mycobacterium tuberculosis, Recombinant (His) Peptidase M,map-1,Methionine aminopeptidase 1	Mycobacterium tuberculosis	E. coli
	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. MeTAP1 Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 32.9 kDa and the accession ...
TMPJ-00247	METAP1 Protein, Human, Recombinant METAP1,Methionine aminopeptidase 1,MAP 1,MetAP 1,Pe...	Human	E. coli
	Methionine Aminopeptidase 1 is a member of the M24 family of metalloproteases. METAP1 plays an important role in G(2)/M phase regulation of the cell cycle and may serve as a promising target for the discovery and development of new anticancer agents. METAP1 and METAP2 have different substrate specificity due to the differences in both size and shape of the active sites. The proteolytic removal of N-terminal methionine from nascent peptides is catalyzed by a family of enzymes known as methionine...
TMPH-01692	MAPK3 Protein, Human, Recombinant (His) MAP kinase isoform p44,p44-ERK1,MAPK3,Extr...	Human	E. coli
	Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, c...
TMPK-01126	MASP2 Protein, Mouse, Recombinant (His) MASP-2,MAP19,MASP1P1,sMap	Mouse	E. coli
	MASP2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.6 kDa and the accession number is Q91WP0.
TMPK-00581	MASP2 Protein, Rat, Recombinant (E. coli, His) sMap,MASP-2,MASP1P1,MAP19	Rat	E. coli
	MASP2 Protein, Rat, Recombinant (E. coli, His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.7 kDa and the accession number is A2VCV7.
TMPK-00705	MASP2 Protein, Human, Recombinant (His) MAP19,sMap,MASP-2,MASP1P1	Human	E. coli
	The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood. One case-control study has reported an association between susceptibility to SARS and mannan-binding lectin (MBL) in China. As the downstream protein of MBL, variants of the MBL-associated serine protease-2 (MASP2) gene may be associated with SARS coronavirus (SARS-CoV) infection in the same population.
TMPK-00496	MASP2 Protein, Cynomolgus, Recombinant (His) MAP19,MASP1P1,MASP-2,sMap	Cynomolgus	E. coli
	MASP2 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.8 kDa and the accession number is A0A2K5UJY0.
TMPK-00582	MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated MASP1P1,MAP19,sMap,MASP-2	Rat	E. coli
	MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.7 kDa and the accession number is A2VCV7.
TMPY-00018	METAP2 Protein, Human, Recombinant (His) MAP2,MNPEP,p67eIF2,methionyl aminopeptidase 2,p67	Human	Baculovirus Insect Cells
	METAP2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.3 kDa and the accession number is A0A140VJE3.
TMPK-00789	CD228 Protein, Human, Recombinant (His) MFI2,MAP97,MELTF,Melanotransferrin,CD228	Human	HEK293 Cells
	Melanotransferrin is typically overexpressed in melanoma cells compared to other cell types - including cancer cells - and is efficiently sorted and secreted with nanovesicles, or so-called exosomes, due to its membrane-anchoring by a glycosylphosphatidylinositol. Melanotransferrin is exposed on the surface of exosomes and is accessible for antibody recognition.
TMPY-06607	MFI2 Protein, Human, Recombinant (His) MTF1,melanotransferrin,CD228,MTf,MAP97	Human	HEK293 Cells
	MFI2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 77.47 kDa and the accession number is P08582-1.
TMPH-02995	MAP_1030 Protein, Mycobacterium paratuberculosis, Recombinant (His) Probable transcriptional regulatory protein MAP_103...	Mycobacterium paratuberculosis	P. pastoris (Yeast)
	MAP_1030 Protein, Mycobacterium paratuberculosis, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 28.8 kDa and the accession number is P62039.
TMPH-01693	MAP3K14 Protein, Human, Recombinant (His & Myc) MAP3K14,Serine/threonine-protein kinase NIK,NF-kapp...	Human	E. coli
	Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P100, which leads to activation of NF-kappa-B via the non-canonical pathway. Could act in a receptor-selective manner.
TMPY-03340	MAP1LC3A Protein, Human, Recombinant (His) LC3,ATG8E,microtubule-associated protein 1 light chain 3 alp...	Human	E. coli
	LC3A, also known as MAP1LC3A, is one of the light chain subunits that function together with both MAP1A and/or MAP1B. MAP1A and MAP1B are microtubule-associated proteins that mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. As a light chain subunit, MAP1LC3A has an important part in neuronal development and in maintaining the balance between neuronal plasticity and r...
TMPJ-01321	MAP1LC3B Protein, Human, Recombinant Autophagy-related ubiquitin-like modifier LC3 B,MAP...	Human	E. coli
	Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B) is a member of the highly conserved ATG8 protein family. ATG8 proteins are present in all known eukaryotic organisms. MAP1LC3B is one of the four genes in the MAP1LC3 subfamily (others include MAP1LC3A, MAP1LC3C, and MAP1LC3B2). It is moat abundantly expressed in heart, brain, skeletal muscle and testis. LMAP1LC3B is a subunit of neuronal microtubule and functions in formation of autophagosomal vacuoles (autophagosomes). It associat...
TMPY-04389	MAP3K8 Protein, Human, Recombinant (GST) TPL2,MEKK8,EST,ESTF,COT,Tpl-2,c-COT,AURA2,mitogen-activated ...	Human	Baculovirus Insect Cells
	Mitogen-activated protein kinase kinase kinase 8, also known as Cancer Osaka thyroid oncogene, Proto-oncogene c-Cot, Serine/threonine-protein kinase cot, Tumor progression locus 2 and MAP3K8, is a cytoplasm protein that belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase kinase subfamily. MAP3K8 is expressed in several normal tissues and human tumor-derived cell lines. Isoform 1 of MAP3K8 is activated specifically during the S and G2/M phases of the...
TMPH-01250	MAP2K3 Protein, Human, Recombinant (His & SUMO) MAP2K3,MAPK/ERK kinase 3,Dual specificity ...	Human	E. coli
	Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14. MAP2K3 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 55.3 kDa and the accession numbe...
TMPY-04410	MAP4K5 Protein, Human, Recombinant (His & GST) KHS,GCKR,MAPKKKK5,mitogen-activated protein kinase ...	Human	Baculovirus Insect Cells
	Mitogen-activated protein kinase kinase kinase kinase 5, also known as Kinase homologous to SPS1/STE2, MAPK/ERK kinase kinase kinase 5, MEK kinase kinase 5, and MAP4K5, is a cytoplasm protein that belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and STE2 subfamily. MAP4K5 is ubiquitously expressed in all tissues examined, with high levels in the ovary, testis, and prostate. It contains one CNH domain and one protein kinase domain. MAP4K5 is highly similar to yeast SPS...
TMPH-01684	MAP1LC3C Protein, Human, Recombinant (His) MAP1A/MAP1B light chain 3 C,Microtubule-as...	Human	E. coli
	Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruits all ATG8 family members to infecting bacteria such as S.Typhimurium. May also play a role in aggrephagy, the macroautophagic degradation of ubiquitinated and aggregated proteins. MAP1LC3C Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 20.7 kDa and the accession number is Q9BXW...
TMPY-04412	Germinal Center Kinase/MAP4K2 Protein, Human, Recombinant (His & GST) mitogen-activated protein kinase kinase kinase kinase 2,GCK,...	Human	Baculovirus Insect Cells
	Mitogen-activated protein kinase kinase kinase kinase 2, also known as B lymphocyte serine/threonine-protein kinase, Germinal center kinase, MAPK/ERK kinase kinase kinase 2, MEK kinase kinase 2, Rab8-interacting protein, and MAP4K2, is cytoplasm and peripheral membrane protein that belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and STE2 subfamily. MAP4K2 contains one CNH domain and one protein kinase domain. Although this kinase is found in many tissues, its express...
TMPH-02994	MAP_1030 Protein, Mycobacterium paratuberculosis, Recombinant (E. coli, His) Probable transcriptional regulatory protein MAP_103...	Mycobacterium paratuberculosis	E. coli
	MAP_1030 Protein, Mycobacterium paratuberculosis, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 32.8 kDa and the accession number is P62039.
TMPK-01414	Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein, Mouse, MHC (His & Avi) Qa-1b,Qdm,MHC,H2-T23	Mouse	HEK293 Cells
	Qa-1b binds a peptide (AMAPRTLLL), referred to as Qdm (for Qa-1 determinant modifier), derived from the signal sequence of murine class Ia molecules. This peptide binds with high affinity and accounts for almost all of the peptides associated with this molecule. Human histocompatibility leukocyte antigen (HLA)-E, a homologue of Qa-1b, binds similar peptides derived from human class Ia molecules and interacts with CD94/NKG2 receptors on natural killer cells.
TMPY-01461	EMAP-II/AIMP1 Protein, Human, Recombinant (His) SCYE1,p43,EMAPII,aminoacyl tRNA synthetase complex-...	Human	E. coli
	EMAP-II/AIMP1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 35 kDa and the accession number is Q12904-1.
TMPY-04378	MAPKAPK3 Protein, Human, Recombinant (GST) mitogen-activated protein kinase-activated protein kinase 3,...	Human	Baculovirus Insect Cells
	The MAPKAP kinases are a group of MAP kinase substrates that are themselves kinases. In response to activation, the MAP kinases phosphorylate downstream components on a consensus Pro-X-Ser/Thr-Pro motif. Several kinases that contain this motif have been identified and serve as substrates for the ERK and p38 MAP kinases. Mitogen-activated protein (MAP) kinase-activated protein kinase 3, also known as MAPKAPK-3 and 3pK, is a member of the Ser/Thr protein kinase family. It is widely expressed in hu...
TMPY-04425	PRAK/MAPKAPK5 Protein, Human, Recombinant (His & GST) PRAK,MAPKAP-K5,MK-5,mitogen-activated protein kinas...	Human	Baculovirus Insect Cells
	MAPKAPK5 contains 1 protein kinase domain and belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family. MAPKAPK5 has significant sequence homology to mitogen-activated protein kinase (MAPK)-activated protein kinase (MAPKAPK). It is widely distributed. MAPKAPK5 can be phosphorylated by an extracellular-regulated kinase (ERK), and p38 kinase but not by c-jun N-terminal kinase (JNK)in vitro. Recombinant GST-MAPKAPK5 protein can phosphorylate a peptide derived from the regulator...
TMPK-01452	HLA-E*01:03&B2M&Peptide (VMAPKTLVL) Monomer Negative Control Protein, Human, MHC (His & Avi) HLAE,MHC class I antigen E,MHC,QA1,sHLA-E	Human	HEK293 Cells
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules ...
TMPK-01514	HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi) sHLA-E,MHC class I antigen E,MHC HLA-E alpha-1,MHC,HLAE,QA1,...	Human	HEK293 Cells
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules ...
TMPH-03100	PMAP-23 Protein, Pig, Recombinant (His & SUMO) PMAP23,Antibacterial peptide PMAP-23,Myelo...	Sus scrofa (Pig)	E. coli
	Exerts antimicrobial activity against both Gram-positive and negative bacteria at concentrations of 2-16 micro molar. Its activity appears to be mediated by its ability to damage bacterial membranes. PMAP-23 Protein, Pig, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 19.0 kDa and the accession number is P49930.
TMPH-02075	Semaphorin-3B/SEMA3B Protein, Human, Recombinant (His & Myc) Sema A(V),Semaphorin-V,Semaphorin-3B,SEMA3...	Human	Baculovirus Insect Cells
	Semaphorin-3B/SEMA3B Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.
TMPY-04551	p38 delta/MAPK13 Protein, Human, Recombinant (GST) MAPK13,p38δ,PRKM13,MAPK-13,mitogen-activat...	Human	Baculovirus Insect Cells
	p38 delta/MAPK13 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 68.4 kDa and the accession number is O15264.
TMPJ-01285	ERMAP Protein, Human, Recombinant (His) SC,RD,ERMAP,Scianna Blood Group Antigen,Radin Blood...	Human	HEK293 Cells
	ERMAP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 16 KDa and the accession number is Q96PL5.
TMPK-00696	PRAK/MAPKAPK5 Protein, Human, Recombinant (Strep-II) MAPKAPK5,MK5,MAPKAP-K5,MK-5,MAPKA...	Human	Baculovirus Insect Cells
	The p38 mitogen-activated protein kinase (MAPK) pathway plays an important role in cellular responses to inflammatory stimuli and environmental stress. p38 regulated/activated protein kinase (PRAK, also known as mitogen-activated protein kinase activated protein kinase 5 [MAPKAPK5]) functions downstream of p38alpha and p38beta in mediating the signaling of the p38 pathway.
TMPJ-01284	ERMAP Protein, Human, Recombinant (hFc) Erythroid Membrane-Associated Protein,RD,ERMAP,Radi...	Human	HEK293 Cells
	ERMAP Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 40-55 KDa and the accession number is Q96PL5.
TMPH-02074	Semaphorin-3B/SEMA3B Protein, Human, Recombinant (His) Sema A(V),Semaphorin-3B,Semaphorin-V,SEMA3...	Human	E. coli
	Semaphorin-3B/SEMA3B Protein, Human, Recombinant (His) is expressed in E. coli.
TMPK-01545	HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi), Biotinylated sHLA-E,MHC,MHC class I antigen E,HLAE,MHC HLA-E alpha-1,MHC ...	Human	HEK293 Cells
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules ...
TMPK-00867	EMAP-II/AIMP1 Protein, Mouse, Recombinant (His) p43,SCYE1,HLD3,EMAP-II,AIMP1,EMAP-2	Mouse	E. coli
	The potent antiangiogenic and proinflammatory protein Endothelial Monocyte Activating Polypeptide II (EMAP II) has been described as a mediator of pulmonary vascular and alveolar formation and its expression is inversely related to the periods of vascularization and alveolarization in the developing lung. Hence the study of EMAP II could play a vital role in studying and devising appropriate therapeutics for diseases of aberrant lung development, such as BPD.
TMPH-02077	Semaphorin-3G/SEMA3G Protein, Human, Recombinant (His & Myc) Semaphorin sem2,Semaphorin-3G,SEMA3G	Human	HEK293 Cells
	Semaphorin-3G/SEMA3G Protein, Human, Recombinant (His & Myc) is expressed in HEK293.
TMPH-01639	MAPK1IP1L Protein, Human, Recombinant (hFc) Mitogen-activated protein kinase 1-interacting protein 1-lik...	Human	HEK293 Cells
	N/A. MAPK1IP1L Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 53.1 kDa and the accession number is Q8NDC0.
TMPY-04531	p38 delta/MAPK13 Protein, Human, Recombinant (GST), Activated in vitro P38 δ/MAPK13,MAPK13,PRKM13,MAPK-1...	Human	Baculovirus Insect Cells
	p38 delta/MAPK13 Protein, Human, Recombinant (GST), Activated in vitro is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 68.4 kDa and the accession number is O15264.
TMPY-03015	EMAP-II/AIMP1 Protein, Mouse, Recombinant AIMP1,p43,Scye1,EMAPII,aminoacyl tRNA synthetase co...	Mouse	E. coli
	EMAP-II/AIMP1 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is Q62386.
TMPK-01541	HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi), Biotinylated QA1,MHC HLA-E alpha-2.1,MHC,HLAE,MHC class I antigen E,MHC H...	Human	HEK293 Cells
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules ...
TMPK-01544	HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi) MHC class I antigen E,HLAE,sHLA-E,QA1,MHC HLA-E alpha-2.1,MH...	Human	HEK293 Cells
	HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules ...
TMPH-02495	APMAP Protein, Mouse, Recombinant (His & Myc) Adipocyte plasma membrane-associated protein,Protein DD16,Ap...	Mouse	E. coli
	Exhibits strong arylesterase activity with beta-naphthyl acetate and phenyl acetate. May play a role in adipocyte differentiation. APMAP Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 47.3 kDa and the accession number is Q9D7N9.
TMPH-02786	MAPK14 Protein, Mouse, Recombinant (His & Myc) Mapk14,Mitogen-activated protein kinase p38 alpha,C...	Mouse	E. coli
	MAPK14 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 48.6 kDa and the accession number is P47811.
TMPY-04429	p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST) ERK3,SAPK3,PRKM12,ERK6,P38γ,P38GAMMA,mitogen-activated prote...	Human	Baculovirus Insect Cells
	p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69.8 kDa and the accession number is P53778.
TMPY-04430	p38 gamma/MAPK12 Protein, Human, Recombinant mitogen-activated protein kinase 12,SAPK-3,P38 γ/MAP	Human	Baculovirus Insect Cells
	p38 gamma/MAPK12 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 42.1 kDa and the accession number is P53778.
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重组蛋白

MAP1D Protein, Human, Recombinant (His)

Cat.No: TMPY-01344

Species: Human

Expression System: Baculovirus Insect Cells

Methionine aminopeptidase Protein, E. coli, Recombinant (His & SUMO)

Cat.No: TMPH-00654

Species: E. coli

Expression System: E. coli

MetAP Protein, Mycoplasma pneumoniae, Recombinant (His & SUMO)

Cat.No: TMPH-03029

Species: Mycoplasma pneumoniae

Expression System: E. coli

MPK5 Protein, Japonica rice, Recombinant (His & Myc)

Cat.No: TMPH-03072

Species: Rice

Expression System: E. coli

MeTAP1 Protein, Mycobacterium tuberculosis, Recombinant (His)

Cat.No: TMPH-03018

Species: Mycobacterium tuberculosis

Expression System: E. coli

METAP1 Protein, Human, Recombinant

Cat.No: TMPJ-00247

Species: Human

Expression System: E. coli

MAPK3 Protein, Human, Recombinant (His)

Cat.No: TMPH-01692

Species: Human

Expression System: E. coli

MASP2 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01126

Species: Mouse

Expression System: E. coli

MASP2 Protein, Rat, Recombinant (E. coli, His)

Cat.No: TMPK-00581

Species: Rat

Expression System: E. coli

MASP2 Protein, Human, Recombinant (His)

Cat.No: TMPK-00705

Species: Human

Expression System: E. coli

MASP2 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00496

Species: Cynomolgus

Expression System: E. coli

MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated

Cat.No: TMPK-00582

Species: Rat

Expression System: E. coli

METAP2 Protein, Human, Recombinant (His)

Cat.No: TMPY-00018

Species: Human

Expression System: Baculovirus Insect Cells

CD228 Protein, Human, Recombinant (His)

Cat.No: TMPK-00789

Species: Human

Expression System: HEK293 Cells

MFI2 Protein, Human, Recombinant (His)

Cat.No: TMPY-06607

Species: Human

Expression System: HEK293 Cells

MAP_1030 Protein, Mycobacterium paratuberculosis, Recombinant (His)

Cat.No: TMPH-02995

Species: Mycobacterium paratuberculosis

Expression System: P. pastoris (Yeast)

MAP3K14 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01693

Species: Human

Expression System: E. coli

MAP1LC3A Protein, Human, Recombinant (His)

Cat.No: TMPY-03340

Species: Human

Expression System: E. coli

MAP1LC3B Protein, Human, Recombinant

Cat.No: TMPJ-01321

Species: Human

Expression System: E. coli

MAP3K8 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04389

Species: Human

Expression System: Baculovirus Insect Cells

MAP2K3 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01250

Species: Human

Expression System: E. coli

MAP4K5 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04410

Species: Human

Expression System: Baculovirus Insect Cells

MAP1LC3C Protein, Human, Recombinant (His)

Cat.No: TMPH-01684

Species: Human

Expression System: E. coli

Germinal Center Kinase/MAP4K2 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04412

Species: Human

Expression System: Baculovirus Insect Cells

MAP_1030 Protein, Mycobacterium paratuberculosis, Recombinant (E. coli, His)

Cat.No: TMPH-02994

Species: Mycobacterium paratuberculosis

Expression System: E. coli

Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein, Mouse, MHC (His & Avi)

Cat.No: TMPK-01414

Species: Mouse

Expression System: HEK293 Cells

EMAP-II/AIMP1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01461

Species: Human

Expression System: E. coli

MAPKAPK3 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04378

Species: Human

Expression System: Baculovirus Insect Cells

PRAK/MAPKAPK5 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04425

Species: Human

Expression System: Baculovirus Insect Cells

HLA-E*01:03&B2M&Peptide (VMAPKTLVL) Monomer Negative Control Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01452

Species: Human

Expression System: HEK293 Cells

HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01514

Species: Human

Expression System: HEK293 Cells

PMAP-23 Protein, Pig, Recombinant (His & SUMO)

Cat.No: TMPH-03100

Species: Sus scrofa (Pig)

Expression System: E. coli

Semaphorin-3B/SEMA3B Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02075

Species: Human

Expression System: Baculovirus Insect Cells

p38 delta/MAPK13 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04551

Species: Human

Expression System: Baculovirus Insect Cells

ERMAP Protein, Human, Recombinant (His)

Cat.No: TMPJ-01285

Species: Human

Expression System: HEK293 Cells

PRAK/MAPKAPK5 Protein, Human, Recombinant (Strep-II)

Cat.No: TMPK-00696

Species: Human

Expression System: Baculovirus Insect Cells

ERMAP Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-01284

Species: Human

Expression System: HEK293 Cells

Semaphorin-3B/SEMA3B Protein, Human, Recombinant (His)

Cat.No: TMPH-02074

Species: Human

Expression System: E. coli

HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01545

Species: Human

Expression System: HEK293 Cells

EMAP-II/AIMP1 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00867

Species: Mouse

Expression System: E. coli

Semaphorin-3G/SEMA3G Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02077

Species: Human

Expression System: HEK293 Cells

MAPK1IP1L Protein, Human, Recombinant (hFc)

Cat.No: TMPH-01639

Species: Human

Expression System: HEK293 Cells

p38 delta/MAPK13 Protein, Human, Recombinant (GST), Activated in vitro

Cat.No: TMPY-04531

Species: Human

Expression System: Baculovirus Insect Cells

EMAP-II/AIMP1 Protein, Mouse, Recombinant

Cat.No: TMPY-03015

Species: Mouse

Expression System: E. coli

HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01541

Species: Human

Expression System: HEK293 Cells

HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01544

Species: Human

Expression System: HEK293 Cells

APMAP Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02495

Species: Mouse

Expression System: E. coli

MAPK14 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02786

Species: Mouse

Expression System: E. coli

p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04429

Species: Human

Expression System: Baculovirus Insect Cells

p38 gamma/MAPK12 Protein, Human, Recombinant

Cat.No: TMPY-04430

Species: Human

Expression System: Baculovirus Insect Cells

--------- 更多 ---------

Cat. No.	Product Name	Target	Signaling Pathways
TMID-0207	Maprotiline-d5 Hydrochloride
	Maprotiline-d5 Hydrochloride 是 Maprotiline Hydrochloride 的氘代化合物。Maprotiline Hydrochloride 的 CAS 号为 10347-81-6。Maprotiline hydrochloride 是一种桥环四环类抗抑郁药，是去甲肾上腺素重吸收抑制剂。
T70960	Maprotiline-d3 hydrochloride
	Maprotiline-d3 is intended for use as an internal standard for the quantification of maprotiline by GC- or LC-MS. Maprotiline is a tricyclic antidepressant. It binds to the norepinephrine transporter (NET) and is selective for NET over the serotonin and dopamine transporters. Maprotiline also binds to the serotonin (5-HT) receptor subtype 5-HT2A, as well as histamine H1, muscarinic acetylcholine, α1-adrenergic, and dopamine D2 receptors. In vivo, maprotiline inhibits norepinephrine reuptake in r...
TMIJ-0489	Coumaphos-d10
	Coumaphos-d10 是 Coumaphos 的氘代化合物。Coumaphos 的 CAS 号为 56-72-4。

同位素标记化合物

Maprotiline-d5 Hydrochloride

Cat.No: TMID-0207

Maprotiline-d3 hydrochloride

Cat.No: T70960

Cat.No: TMIJ-0489

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