432
47
12
1
184
10
Cat. No. | Product Name | ||
---|---|---|---|
L7300 | 钾通道分子库 | 152 compounds | |
152 种钾通道相关化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L2151 | 化疗药物库 | 48 compounds | |
48 个肿瘤化疗药物,可以用于高通量和高内涵筛选; | |||
L4100 | TGF-β/Smad靶点化合物库 | 184 compounds | |
184 个 TGF-β/Smad 靶点相关的小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L8300 | 染色质修饰分子库 | 250 compounds | |
250 种染色质化学修饰相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L8000 | 干细胞分化化合物库 | 1197 compounds | |
1197 种干细胞分化信号通路相关的生物活性小分子化合物的特有集合,可用于高通量、高内涵筛选; | |||
L6710 | 中药抗炎分子库 | 1246 compounds | |
1246 种具有抗炎活性或靶向炎症相关靶点的中药单体集合,是药物开发、药理研究的有效工具; | |||
L7200 | 钙通道分子库 | 140 compounds | |
140 种钙通道相关化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L6140 | 糖类及苷类化合物库 | 595 compounds | |
595 种糖类或苷类的化合物,可用于高通量筛选和高内涵筛选; | |||
L9240 | 农药化合物库 | 270 compounds | |
270种农药相关化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L5300 | 线粒体靶向库 | 812 compounds | |
812 种具有潜在或确定线粒体靶向活性的化合物,以促进针对线粒体的药物研究; | |||
L2190 | 抗肺癌化合物库 | 1702 compounds | |
1702 种与肺癌相关的化合物,可以用于抗肺癌药物研发和药理研究; | |||
L2170 | 肿瘤免疫治疗小分子化合物库 | 449 compounds | |
449 种靶向肿瘤免疫治疗靶点的小分子,可用于高通量和高内涵筛选,是研究肿瘤免疫治疗的有力工具; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
C0051 |
Penicillin-Streptomycin Solution (100×), Sterile
青霉素-链霉素双抗溶液(100×),灭菌 |
Solution in bottle |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T38260 |
SP 600125, negative control
JNK Inhibitor II, negative control |
Others | Others |
SP 600125, negative control 是 SP 600125 的甲基化类似物,可用作SP 600125的阴性对照,对 DTP3和GADD45β/MKK7(生长停滞和 DNA 损伤诱导型 β/介原活化蛋白激酶激酶 7)具有抑制作用,能够恢复活化。SP 600125, negative control 对 JNK2 和 JNK3 的 IC50s 分别为 18 和 24 μM。 | |||
TP1555L1 |
Fibronectin Active Fragment Control acetate
Fibronectin Active Fragment Control acetate(97461-84-2 Free base) |
||
Fibronectin Active Fragment Control acetate 是纤连蛋白的活性片段,这是一种糖蛋白。 | |||
TP1833L |
SLLK, Control Peptide for TSP1 Inhibitor acetate
SLLK, Control Peptide for TSP1 Inhibitor acetate(464924-27-4,free base) |
Others | Others |
SLLK, Control Peptide for TSP1 Inhibitor acetate(464924-27-4,free base) 是 LSKL 的对照肽。 | |||
TP2180L |
Compstatin control peptide acetate
|
Complement System | Immunology/Inflammation |
Compstatin control peptide acetate 是补体蛋白 C3 的抑制剂,通过结合和抑制补体 C3 的切割。 | |||
T84727 |
Necrostatin-1 (inactive control)
Nec-1 (inactive control) |
Others | Others |
Necrostatin-1(Nec-1)(inactive control)为Necrostatin-1的非活性类似物,后者为一种高效的坏死性凋亡抑制剂。 | |||
T37559 |
NF-κB Control
|
Others | Others |
NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. It blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α. NF-κB control is a peptide that is identical in sequence to NF-κB inhibitor, except two essential, basic residues of the p105 NLS are substituted with non-basic amino acids... | |||
T39317 |
ELA-14 negative control
|
||
ELA-14 negative control is an inactive peptide that serves as a negative control for ELA-14. | |||
T78337 |
Mouse IgG2a kappa, Isotype Control
|
||
Mouse IgG2a kappa, Isotype Control 是鼠源IIgG2a kappa 抗体的同型抗体。 | |||
T41227 |
ARCC 4 negative control
|
Others | Others |
ARCC 4 negative control is a negative control for ARCC 4. Binds androgen receptors (AR) without inducing degradation. | |||
TP1357 |
Human IgG1 Control
|
||
Human IgG1 Control was purified from Human serum by chromatography.Human IgG1 Control can be used as a Control, standard, blocking agent, or coating protein in a variety of experiments, including ELISA, Western and blotting, immunoprecipitation, and immun | |||
TP2130L |
Rac1 Inhibitor F56, control peptide acetate
Rac1 Inhibitor F56, control peptide acetate(1315378-77-8 free base) |
Rho | Cell Cycle/Checkpoint |
Rac1 Inhibitor F56, control peptide acetate(1315378-77-8 free base) 是 Rac1 Inhibitor 的对照肽版本;包含Rac1的残基45-60,其中Trp56被Phe 取代。不影响 GEF-Rac1 相互作用。 | |||
T36247 |
TBK1 control PROTAC® 4
|
Others | Others |
Negative control for TBK1 PROTAC 3i. Binds TBK1 with high affinity, but exhibits no significant degradation of TBK1. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license. | |||
T36580 |
Glucagon Receptor Antagonist Inactive Control
|
Others | Others |
Glucagon Receptor Antagonist Inactive Control 是一种 Glucagon 受体拮抗剂,可用于生命科学领域的相关研究。其产品编号为 T36580,CAS号为 362482-00-6。 | |||
TP1833 |
SLLK, Control Peptide for TSP1 Inhibitor(TFA)
SLLK, Control Peptide for TSP1 Inhibitor,SLLK,TSP1抑制剂控制肽 |
||
SLLK is a control peptide for LSKL. | |||
TP1450 |
SLLK, Control Peptide for TSP1 Inhibitor(TFA) (464924-27-4 free base)
SLLK, Control Peptide for TSP1 Inhibitor(TFA) |
||
SLLK, Control Peptide for TSP1 Inhibitor (TFA) is a control peptide for LSKL, which is a Thrombospondin (TSP-1) inhibitor. | |||
TP1555 |
Fibronectin Active Fragment Control
|
||
Fibronectin is a high-molecular weight (~440kDa) extracellular matrix glycoprotein that binds to membrane-spanning receptor proteins called integrins.In addition to integrins, fibronectin also binds extracellular matrix components such as collagen, fibrin | |||
TP2130 |
Rac1 Inhibitor F56, control peptide
|
||
Control peptide version of Rac1 Inhibitor; comprises residues 45-60 of Rac1 with Trp56 replaced by Phe. Does not affect GEF-Rac1 interaction. | |||
TP2203 |
Bax inhibitor peptide, negative control
|
Others | Others |
The compound is a negative control peptide for the Bax inhibitor peptides V5 and P5. | |||
T78339 |
Human IgG4 (S228P) kappa, Isotype Control
|
Others | Others |
Human IgG4 (S228P) kappa, Isotype Control是人-鼠嵌合型抗体,可用研究自身免疫疾病。 | |||
TP2039 |
Dynamin inhibitory peptide, myristoylated (control)
|
||
Control peptide version of dynamin inhibitory peptide, myristoylated, an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. In contrast to dynamin inhibitory peptide, has no significant eff | |||
T71316 |
ERK Inhibitor II (Negative control)
|
Others | Others |
ERK InhibitorII (Negative control)为高效的细胞外信号调节激酶(ERK)抑制剂,能抑制胰岛素受体(Insulin Receptor)激活,适用于糖尿病研究。 | |||
T41214 |
(S)-BAY-293
BAY 294,BAY 293 Negative Control |
Ras | GPCR/G Protein; MAPK |
(S)-BAY-293 是一种有效的 pan-KRAS 抑制剂,可用于研究原发性非小肺癌和胰腺癌。 | |||
T35059 |
VinSpinIC
Vinnie's Spindlin Inactive Control,TD020826a |
Others | Others |
VinSpinIC is an inactive control for VinSpinIn. | |||
T74869 |
SiRNA Negative Control
|
Others | Others |
SiRNA Negative Control 是 21个核苷酸的 siRNA,可作为阴性对照使用。 | |||
T23150 |
PHGDH-inactive
|
Others | Others |
PHGDH-inactive 对 PHGDH 无活性,IC50大于57 μM,可用作 NCT-502 和 NCT-503 的阴性对照。 | |||
T81317 |
Rabbit IgG1 kappa, Isotype Control
|
||
RabbitIgG1kappa, Isotype Control为兔源IgG1κ同型对照单克隆抗体,用于科研中作为Rabbit IgG1κ抗体的实验对照。 | |||
T81756 |
Mouse IgG3 kappa, Isotype Control
|
||
MouseIgG3kappa, Isotype Control为鼠源单克隆抗体,充当mouse IgG3κ抗体的同型对照。 | |||
T78244 |
Human IgG4 kappa, Isotype Control
|
||
HumanIgG4kappa Isotype Control为人源化单克隆抗体,用作human IgG4κ抗体的同型对照。 | |||
T81757 |
Mouse IgG2c kappa, Isotype Control
|
||
MouseIgG2ckappa, Isotype Control为mouse IgG2cκ同型对照的鼠源单克隆抗体。 | |||
T81758 |
Mouse IgG2b kappa, Isotype Control
|
||
MouseIgG2bkappa Isotype Control是mouse IgG2bκ抗体的同型对照,属于鼠源单克隆抗体。 | |||
T78336 |
Mouse IgG1 kappa, Isotype Control
|
||
MouseIgG1kappa Isotype Control 为 mouse IgG1κ 抗体的同型对照鼠源单克隆抗体。 | |||
T78242 |
Human IgG1 kappa, Isotype Control
|
||
HumanIgG1kappa, Isotype Control为人源化单克隆抗体,作为human IgG1κ抗体的同型对照物。 | |||
T82156 |
Human IgG3 kappa, Isotype Control
|
||
HumanIgG3kappa, Isotype Control为人-鼠嵌合型抗体,作为human IgG3κ抗体同型对照使用。 | |||
T82157 |
Human IgG1 lambda1, Isotype Control
|
||
HumanIgG1lambda1, Isotype Control为人-鼠嵌合型单克隆抗体,作为human IgG1λ1抗体的同型对照物。 | |||
T78338 |
Rat IgG1 kappa, Isotype Control
|
||
RatIgG1kappa(Isotype Control)是Rat IgG1κ抗体同型对照的鼠源性单克隆抗体。 | |||
T78243 |
Human IgG2 kappa, Isotype Control
|
||
HumanIgG2kappa, Isotype Control为人源化单克隆抗体,作为human IgG2κ抗体的标准同型对照使用。 | |||
T78041 |
Tat-peptide control 168-189 TFA
|
||
Tat-peptide 168-189 是一款标记有 Tat 的细胞渗透融合肽,对应回大鼠 G3BP1 的168-189残基。此配合物末端整合了HIV Tat 序列的一个高度非保守部分,以促进其穿透细胞膜。作为Tat-peptide 168-189 TFA的阴性对照,Tat-peptide 168-189 TFA 已被证实可促进轴突生长和增加神经元的突触数目。 | |||
T19578 |
TH-263
|
Others | Others |
TH-263 是二芳基磺酰胺衍生物,可用作 TH-257 的阴性对照,对 LIMK1 和 LIMK2 均无抑制活性。 | |||
T78340 |
Human IgG1 (N297A) kappa, Isotype Control
|
||
HumanIgG1(N297A) kappa, Isotype Control为具有人-鼠嵌合结构的抗体,作为HumanIgG1(N297A)κ 抗体的同型对照物。 | |||
T82161 |
Human IgG1 (D265A) kappa, Isotype Control
|
||
HumanIgG1(D265A) kappa, Isotype Control是一种人鼠嵌合型抗体,用作HumanIgG1(D265A)κ抗体的同型对照。 | |||
T78341 |
Human IgG1 (F405L) kappa, Isotype Control
|
||
HumanIgG1(F405L) kappa, Isotype Control为人-鼠嵌合型单克隆抗体,作为HumanIgG1(F405L)κ抗体的同型对照使用。 | |||
T82155 |
Human IgG4 (S228P) lambda1, Isotype Control
|
||
HumanIgG4(S228P) lambda1, Isotype Control,为人-鼠嵌合型抗体,作为humanIgG4(S228P) λ1抗体同型对照使用。 | |||
T82160 |
Human IgG1 (D270N) kappa, Isotype Control
|
||
HumanIgG1(D270N) kappa, Isotype Control为人-鼠嵌合型抗体, 作为HumanIgG1(D270N)κ 抗体的同型对照品。 | |||
T81760 |
Mouse IgG1 (D265A) kappa, Isotype Control
|
||
MouseIgG1(D265A) kappa, Isotype Control 为鼠源IgG1 κ类同型对照单克隆抗体,适用作为mouse IgG1(D265A)κ抗体的实验对照。 | |||
T15441 |
GSK8573
|
Epigenetic Reader Domain | Chromatin/Epigenetic |
GSK8573 是 GSK2801 的非活性对照化合物。它与BRD9具有结合活性,Kd 值为 1.04 μM。 | |||
T81755 |
Mouse lgG2a (D265A) kappa, Isotype Control
|
||
Mouse lgG2a (D265A) kappa, Isotype Control 为 mouse lgG2a (D265A) 的鼠源单克隆同型对照抗体。 | |||
T81759 |
Mouse IgG1 (N297A) kappa, Isotype Control
|
||
MouseIgG1(N297A) kappa,Isotype Control 为特定mouse IgG1(N297A)κ 抗体之同型对照,属鼠源单克隆抗体。 | |||
T82159 |
Human IgG1 (K214R) kappa, Isotype Control
|
||
HumanIgG1(K214R) kappa, Isotype Control为HumanIgG1(K214R)κ 抗体的人源化同型对照,属于人-鼠嵌合型抗体。 | |||
T24677 |
PS47
PS 47,PS-47 |
PDK | PI3K/Akt/mTOR signaling |
PS-47(PS 47) 是一种 PS48 的非活性 E-异构体。其中 PS48 是一种 PDK1 的激活剂。PS47 (PS 47) 可用作 PS48 的阴性对照。 | |||
T0961 |
Trometamol
三(羟甲基)氨基甲烷,Tromethamine,缓血酸铵 |
COX | Immunology/Inflammation; Neuroscience |
Trometamol (Tromethamine) 是一种在生理范围内控制 pH 值的有效胺类化合物,也是一种低毒性的生物惰性氨基醇,可以在体内和体外缓冲二氧化碳和酸。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6S2243 |
Alisol A 24-acetate
Alisol A 24-monoacetate,Alisol A monoacetate,泽泻醇A24-醋酸酯 |
Others | Others |
Alisol A 24-acetate (Alisol A monoacetate) 是一种天然产物。 | |||
TQ0195 |
1,5-Anhydrosorbitol
|
Others; Endogenous Metabolite | Metabolism; Others |
1,5-Anhydrosorbitol 是评价短期血糖控制情况的可靠指标,主要来源于食物。 | |||
TN1114 |
Carabrone
|
Antibacterial; Antifection | Microbiology/Virology |
Carabrone 是分离自Carpesium abrotanoides 果实的一种倍半萜,表现出显著抗肿瘤活性和抗菌活性,如灰霉病菌Botrytis cinerea,炭疽病菌Colletotrichum lagenarium 和禾白粉菌Erysiphe graminis。 | |||
T8162 |
Cannabidivarin
Cannabidivarin,GWP-42006,GWP42006,GWP 42006 |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Cannabidivarin (GWP42006) 是一种非拟精神病药大麻素。 它具有缓解多种神经系统疾病 (包括癫痫和自闭症谱系障碍) 的研究潜力。 | |||
T0861 |
Tylosin tartrate
酒石酸泰洛星,酒石酸泰乐菌素 |
Antibacterial; Antibiotic | Microbiology/Virology |
Tylosin tartrate 是一种大环内酯类抗生素,是 Streptomyces fradiae 的产物。它对革兰氏阳性菌具有高效的抗菌活性。它作为饲料添加剂可促进动物生长。它被用于治疗家禽、猪和牛的细菌性痢疾和呼吸道疾病。 | |||
TN1334 |
7-Methoxyrosmanol
7ALPHA-甲氧基迷迭香酚,7-O-Methylrosmanol |
cAMP | GPCR/G Protein |
7-Methoxyrosmanol (7-O-Methylrosmanol) 是一种酚类二萜,从迷迭香中分离得到,可抑制 PEPCK 和 G6Pase 启动子的 cAMP 反应。 | |||
T5786 |
TETRAHYDROPIPERINE
四氢胡椒碱,Cosmoperine |
P450; TRP/TRPV Channel | Membrane transporter/Ion channel; Metabolism |
Tetrahydropiperine (Cosmoperine) 是胡椒碱的环己基类似物,也是一种天然芳基戊酰胺,从Piper longum 分离得到。它对细胞色素 P450 (CYP) 同工型 CYP1A1/芳基烃羟化酶 (AHH;IC50=23 µM)具有抑制作用。 | |||
T2O2774 |
L-Asparagine
alpha-aminosuccinamic acid,L-天门冬氨酸,(-)-Asparagine,Asparamide,2-Aminosuccinamic acid,Asn,Altheine |
Endogenous Metabolite | Metabolism |
L-Asparagine (Asparamide) 是一种非必需氨基酸,可以参与神经和脑组织细胞功能的代谢控制。 | |||
T20754 |
Deltamethrin
Butoss,RU-22974,Esbecythrin,溴氰菊酯,K-Othrin,Decamethrin,RU 22974 |
Others | Others |
Deltamethrin (RU 22974) 是一种具有神经毒性的拟除虫菊酯杀虫剂,在大鼠中能够产生一系列可逆的运动症状(如包括后肢僵硬、舞蹈性关节炎)。 | |||
T3S0195 |
Nootkatone
诺卡酮,努特卡酮,诺卡酮 |
AMPK | Chromatin/Epigenetic; PI3K/Akt/mTOR signaling |
Nootkatone 是一种神经保护剂,来自于Alpiniae OxyphyllaeFructus ,具有抗氧化和抗炎活性。它能够改善脂多糖诱导的阿尔茨海默氏病小鼠模型的认知障碍。 | |||
T4592 |
TOMATIDINE HYDROCHLORIDE
Tomatidine,Tomatidine HCl,盐酸番茄碱 |
Others; NF-κB; JNK; Autophagy | Autophagy; MAPK; NF-κB; Others |
Tomatidine hydrochloride (Tomatidine HCl) 是一种甾体生物碱,可防止肌肉萎缩并促进肌肉生长。它通过阻断 NF-κB 和JNK 信号发挥抗炎作用,可激活哺乳动物细胞或秀丽隐杆线虫中的自噬。 | |||
T14853 |
Cabergoline
FCE-21336,卡麦角林 |
Dopamine Receptor; 5-HT Receptor; Autophagy | Autophagy; GPCR/G Protein; Neuroscience |
Cabergoline (FCE-21336) 是一种麦角衍生的多巴胺 D2亚类受体激动剂,高亲和力作用于D2、D3和5-HT2B 受体,Ki 分别为 0.7、1.5 和 1.2。 | |||
T4A2462 |
Telocinobufagin
Telobufotoxin,远华蟾蜍精,Telocinobufogenin |
Others | Others |
Telocinobufagin (Telobufotoxin) 是一种从蟾酥中分离提取获得的组份。 | |||
TN1059 |
Ganoderic acid B
|
IL Receptor; HIV Protease; JAK; STAT | Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Microbiology/Virology; Proteases/Proteasome; Stem Cells |
Ganoderic acid B 是从灵芝中分离的一种三萜类天然产物。它是端粒酶抑制剂,抑制 Epstein-Barr 病毒抗原的活化。它是 HIV-1 蛋白酶抑制剂。 | |||
TN3048 |
4-Methoxycinnamaldehyde
p-Methoxycinnamaldehyde |
RSV | Microbiology/Virology |
4-Methoxycinnamaldehyde (p-Methoxycinnamaldehyde) 是 Agastache rugosa 的一种活性成分。4-Methoxycinnamaldehyde 对人喉癌细胞系中的呼吸道合胞病毒 (RSV) 具有细胞保护活性,有助于控制 RSV 感染诱发的疾病,IC50 约为 0.055 μg/mL。 | |||
T1157 |
Moxidectin
milbemycin B,CL301423,莫昔克丁,莫西菌素 |
GluCls; Antibiotic; Parasite | Microbiology/Virology |
Moxidectin (CL301423) 是可用于预防和控制心丝虫和蛔虫的一种驱虫剂。 | |||
T6S0232 |
Eriodictyol
圣草酚,Huazhongilexone |
Influenza Virus; DNA/RNA Synthesis; Nrf2; Endogenous Metabolite | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology |
Eriodictyol (Huazhongilexone) 是从中草药中得到的一种黄酮类天然产物,具有抗氧化、抗炎和抗糖尿病作用。它还是一种流感依赖 RNA 的RNA 聚合酶抑制剂,IC50为 18 nM。它可诱导Nrf2信号通路。 | |||
T20945 |
2,4-D
Hedonal,Macondray,2,4-D acid,Chloroxone,2,4-二氯苯氧乙酸 |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
2,4-Dichlorophenoxyacetic acid (Hedonal) 是一种合成生长素,用作植物生长调节剂,也用作植物细胞培养基中的补充剂。它是除草剂中的一种活性成分,用于破坏肌动蛋白细胞骨架,以控制根系伸长和细胞生成。 | |||
T0414 |
D-Mannitol
Mannite,Mannitol,D-甘露糖醇,Osmitrol |
Apoptosis; Dehydrogenase; Endogenous Metabolite | Apoptosis; Metabolism |
D-Mannitol (Mannitol) 是与山梨醇相关的利尿剂和肾脏诊断辅助剂,具有较弱的肾脏血管扩张活性。 | |||
T6S1653 |
Albiflorin
Alibiflorin,芍药内酯苷 |
Reactive Oxygen Species | Immunology/Inflammation; Metabolism; NF-κB |
Albiflorin (Alibiflorin) 是一种牡丹根中的主要成分,是一种单萜糖苷。它具有神经保护、抗炎、抗氧化和缓解疼痛作用。 | |||
T64744 |
Ovalbumins
|
Endogenous Metabolite | Metabolism |
Ovalbumins 是蛋清中的主要蛋白质。Ovalbumins 具有多种生物活性,如降压、抗菌、抗癌、抗氧化和免疫调节活性。Ovalbumins 是雌激素或孕酮处理的输卵管中合成的丰富的蛋白质。Ovalbumins 通常用作研究激素控制该组织中基因表达的标志物。 | |||
T3891 |
Oroxylin A-7-O-glucuronide
Oroxylin A Glucoronide,千层纸素A-7-0-Β-D-葡萄糖醛酸苷,Oroxyloside,Oroxylin A 7-O-beta-D-glucuronide |
Others | Others |
Oroxylin A-7-O-glucuronide (Oroxylin A Glucoronide) 是一种类黄酮葡糖苷酸,提取自 Scutellaria baicalensis 干燥的根中,具有脯氨酰寡肽酶(POP)抑制作用。 | |||
T3926 |
Echinatin
刺甘草查尔酮,Retrochalcone |
Free radical scavengers | oxidation-reduction |
Echinatin (Retrochalcone) 是分离自中草药甘草中,具有保肝和抗炎活性。在大鼠中,它可以被快速吸收和消除,并广泛分布,绝对生物利用度约为 6.81%。 | |||
T2915 |
Bardoxolone
RTA 401,齐墩果烷三萜化合物,CDDO |
Others; Nrf2 | Immunology/Inflammation; Others |
Bardoxolone (CDDO) 是新型核调节因子激活剂。 | |||
T8270 |
Deserpidine
地舍平,Harmonyl |
RAAS | Endocrinology/Hormones |
Deserpidine (Harmonyl) 是从 Rauwolfia canescens 的根中分离的生物碱。Deserpidine 与 Reserpine 相关。Deserpidine 是竞争性血管紧张素转化酶抑制剂,可以被用作抗高血压药以及镇定剂。Deserpidine 还减少了肾上腺皮质血管紧张素 II 诱导的醛固酮分泌。 | |||
TN2635 |
15-Demethylplumieride
|
Others | Others |
15-Demethylplumieride is a quality control index of Plumeriarubra L. | |||
T23825 |
Bryononic acid
|
||
Bryononic acid is a new cucurbitane-type triterpenoid. Bryonolic acid transcriptional control of anti-inflammatory and antioxidant genes in macrophages in vitro and in vivo. | |||
T78499 |
1,5-Anhydro-D-mannitol
|
Others | Others |
1,5-Anhydro-D-mannitol为1,5-Anhydrosorbitol的非活性类似物,通常用作实验对照。1,5-Anhydrosorbitol则作为评估短期血糖控制的可靠指标。 | |||
TN3989 |
Erycibelline
|
LDL; PPAR | DNA Damage/DNA Repair; Metabolism |
Erycibelline has antiobesity activity, it may be a useful therapeutic agent for body weight control by downregulating adipogenesis and lipogenesis. | |||
TN1024 |
Baldrinal
|
Others | Others |
Baldrinal, valtrate, and acevaltrate are the quality control compounds of Valeriana jatamansi Jones. | |||
TN6564 |
Palustrol
|
||
Palustrol exhibits acaricidal, insecticidal, 'pesticidal' and/or arthropod repellent properties, may be useful sources of chemicals for the control of arthropods of medical, veterinary or agricultural importance. | |||
TMA0925 |
Wilforlide A acetate
|
Others | Others |
Wilforlide A (T1) serves as a quality control standard of Tripterygium Glycosides that be listed in Drug Standard of Ministry of Public Health of the People's Republic of China. T1 has anti-inflammatory effects. | |||
TN1479 |
Celosin J
|
Others | Others |
Celosin H, celosin I, celosin J could be used as chemical markers for the quality control of C. argentea seeds. | |||
T20612 |
4,5,6,7-Tetrachlorophthalide
KF 32,KF32,Rabcide,KF-32,Fthalide |
||
4,5,6,7-Tetrachlorophthalide is a fungicide used for the control of rice blast. It has a role as a melanin synthesis inhibitor and an antifungal agrochemical. | |||
TN3056 | 4-O-Galloylbergenin | Others | Others |
4-O-Galloylbergenin shows significant 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical scavenging activity with EC50 7.8 uM, it shows more antioxidant activity than the positive control vitamin C (EC50 = 28.3 uM). | |||
TN2060 |
Petunidin-3-O-glucoside chloride
|
Others | Others |
Petunidin-3-O-glucoside chloride has significantly higher antioxidant activity than the Fe2+ control. Petunidin-3-O-glucoside causes problems in digestibility, may be important dietary supplements with beneficial health effects. | |||
TN5154 |
Torilolone
|
Others | Others |
Torilin and torilolone show hepatoprotective effects on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells,the EC50 values are 20.6 +/- 1.86 and 3.6 +/- 0.1 microM, respectively; and silybin as a positive control shows an EC50 value of 69.0 | |||
TN3626 |
Cerbinal
|
Antifection | Microbiology/Virology |
Cerbinal 是一种天然化合物,来源于非洲非洲菊的草本植物。它具有杀虫活性,是一种潜在的新型害虫防治剂。 | |||
TN1478 |
Celosin I
|
Others | Others |
Celosin H, celosin I, and celosin J could be used as chemical markers for the quality control of C. argentea seeds. Celosin I exhibited significant hepatoprotective effect on carbon tetrachloride-induced and N,N-dimethylformamide-induced hepatotoxicity in | |||
TN7336 |
Glucobrassicin potassium
|
Others | Others |
Glucobrassicin (potassium) 是一种从野生胡萝卜 (Raphanus raphanistrumL.) 中分离的硫代葡萄糖苷 (GSL),适用于生物熏蒸和化感植物在杂草管理研究中的应用。 | |||
TN5463 |
Leachianone G
|
||
Leachianone G exhibits significant antioxidant potentials in the ABTS, ONOO(-), and total ROS assays, it also shows inhibitory activities against pancreatic lipase, it may be used as drug candidate to control obesity. Leachianone G shows potent antiviral | |||
TN7295 |
(R)-(+)-Tetrahydroberberine
(R)-(+)-Canadine,(+)-Canadine |
Others | Others |
(R)-(+)-Tetrahydroberberine 为 (S)-(-)-Tetrahydroberberine 的非活性异构体,常用作实验对照物。其中,(S)-(-)-Tetrahydroberberine 是生物碱种类,作为小檗碱生物合成路径中的中间体,具备杀虫作用。 | |||
TN4999 |
Serratenediol
|
BCL; PARP; Caspase | Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome |
Serratenediol demonstrates strong inhibitory effects on the Epstein-Barr virus early antigen (EBV-EA) activation without showing any cytotoxicity, its effects being stronger than that of a representative control, oleanolic acid. Serratenediol can promote | |||
T82487 |
Ejaponine A
|
||
Ejaponine A(化合物1)为源于日本卫矛的杀虫倍半萜酯。该化合物展现出强效针对粘虫的活性(LD50为89.2 μg/g),在相关杀粘虫机制研究中得到应用。 | |||
TN2553 |
1-Methyl-2-undecyl-4(1H)-quinolone
1-Methyl-2-undecylquinolin-4(1H)-one |
MAO | Metabolism; Neuroscience |
1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodia rutaecarpa (Juss.) Benth. 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of type B MAO (MAO-B) activity with the IC(50) value of 15.3 microM using a substrate kynuramine, but does not inhibit type A MAO (MAO-A) activity.It can mitigate high phosphate-induced human aortic valve interstitial cells (HAVICs) calcification ... | |||
T35741 |
Gliovirin
|
Others | Others |
Gliovirin is a fungal metabolite that has been found inT. harzianumand has fungicidal, antimicrobial and anti-inflammatory activities.1It is active against the plant pathogenic fungusP. ultimum(MIC = 60 ng/ml) and the parasiteT. brucei brucei(IC50= 90 ng/ml), but has no effect on the plant pathogenic fungiR. solani,P. omnivorum,T. basicola,R. arrhizus, andV. dahliaeor the bacteriaB. thuringiensis,P. fluorescens, andX. malvacearumwhen used at concentrations up to 1,000 ng/ml.2,3Gliovirin decrease... | |||
T36563 |
(E)-Guggulsterone
|
Others | Others |
Bile acids are essential for solubilization and transport of dietary lipids, are the major products of cholesterol catabolism, and are physiological ligands for farnesoid X receptor (FXR), a nuclear receptor that regulates genes involved in lipid metabolism.1They are also inherently cytotoxic, as physiological imbalance contributes to increased oxidative stress.2,3Bile acid-controlled signaling pathways are promising novel targets to treat such metabolic diseases as obesity, type II diabetes, hy... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00527 |
Fibritin Protein, Enterobacteria phage T4, Recombinant (His & SUMO)
wac,Whisker antigen control protein,Collar protein,... |
Enterobacteria phage T4 | E. coli |
Chaperone involved in tail fiber assembly and retraction. Acts as a chaperone helping to attach the long tail fibers to the virus during the assembly process. During phage assembly, twelve fibritin molecules attach to the phage neck via gp13: six molecules forming the collar and six molecules forming the whiskers. | |||
TMPY-06351 |
Virus-Like Particle (VLP) isotype control Protein
|
HEK293 Cells | |
Virus-Like Particle (VLP) isotype control Protein is expressed in HEK293 mammalian cells. | |||
TMPY-04021 |
NPDC1 Protein, Human, Recombinant (His)
CAB1,CAB,NPDC-1,CAB-1,CAB-,neural proliferation, differentia... |
Human | HEK293 Cells |
NPDC1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.9 kDa and the accession number is Q9NQX5. | |||
TMPH-03765 |
Virus-Like Particles (VLPs) isotype control
|
HEK293 Cells | |
Virus-Like Particles (VLPs) isotype control can be used as the control of VLP expressed proteins. | |||
TMPH-01167 |
CDK1 Protein, Human, Recombinant (His)
p34 protein kinase,Cell division control protein 2 ... |
Human | E. coli |
CDK1 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPK-01452 |
HLA-E*01:03&B2M&Peptide (VMAPKTLVL) Monomer Negative Control Protein, Human, MHC (His & Avi)
HLAE,MHC class I antigen E,MHC,QA1,sHLA-E |
Human | HEK293 Cells |
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules ... | |||
TMPK-01246 |
GDF-15 Protein, Mouse, Recombinant (His)
MIC1,Placental TGF-beta,Placental TGF-β,PTGF-beta,PTGFBPTGF-... |
Mouse | E. coli |
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Mouse, Rec... | |||
TMPY-00545 |
Dermcidin Protein, Human, Recombinant (hFc)
AIDD,PIF,HCAP,dermcidin,DCD-1,DSEP |
Human | HEK293 Cells |
Hepatocellular carcinoma (HCC) is a major contributor to cancer-related deaths due to its often late stage diagnosis, and dermcidin (DCD) may have the potential to be used as a serum biomarker for HCC for more timely diagnoses. Human dermcidin (DCD) is an antimicrobial peptide secreted constitutively by sweat glands. And the role of DCD in ischemic heart disease has drawn increasing attention in particular its relationship with insulin secretion and glycemic control, nitric oxide (NO) synthesis ... | |||
TMPJ-00249 |
TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated
TGF-Beta-1,TGFB1,Transforming Growth Factor β-1,Latency-Asso... |
Human | HEK293 Cells |
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family... | |||
TMPY-04329 |
Vimentin Protein, Human, Recombinant (His)
CTRCT30,HEL113,vimentin |
Human | Baculovirus Insect Cells |
Vimentin is a type III intermediate filament (IF) protein found in various non-epithelial cells, especially mesenchymal cells. A vimentin monomer, has a central α-helical domain and carboxyl (tail) domains. Two monomers compose the basic subunit of vimentin assembly. Vimentin is crucial for supporting and anchoring the position of the organelles in the cytosol. Vimentin provided cells with a resilience absent from the microtubule or actin filament networks, when under mechanical stress in vivo. ... | |||
TMPY-04125 |
PTP1B Protein, Human, Recombinant (His)
protein tyrosine phosphatase, non-receptor type 1,PTP1B,PTPN... |
Human | E. coli |
PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1B contains 1 tyrosine-protein p... | |||
TMPY-00541 |
LON PROTEASE Protein, E. coli, Recombinant (His)
|
E. coli | E. coli |
Lon protease, an ATP-dependent mitochondrial protease, is important in mitochondrial protein maintenance. Lon protease is a multifunctional enzyme, and its functions include the degradation of damaged proteins and naturally short-lived proteins, ATPase and chaperone-like activities, as well as DNA binding. Lon protease plays a major role in the protein quality control system in mammalian cell mitochondria. It is present in the mitochondrial matrix and degrades oxidized and misfolded proteins, th... | |||
TMPJ-00662 |
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)
Receptor activator of nuclear factor kappa-B ligand,Receptor... |
Human | E. coli |
CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL is the ligand of nuclear factor (NF)-κB (RANK). When RANKL binds to RANK, it will undergo trimerization and then bind to an adaptor molecule TNF receptor-associated factor 6 (TRAF6). This results in the activation of several downstream signaling cascades, including the NFκB, mitog... | |||
TMPY-06981 |
IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)
interleukin 1 α,IL1,白介素,IL-1F1,IL1-α,IL-1A,IL1F1,白细胞介素,IL-1 ... |
Human | E. coli |
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophage... | |||
TMPY-02521 |
HIST3H2A Protein, Human, Recombinant
histone cluster 3, H2a,MGC3165 |
Human | E. coli |
Histones are a complex family of highly conserved basic proteins responsible for packaging chromosomal DNA into nucleosomes. There are subtype diversities: H1, H2A, H2B, and H3 or H4. It has become more and more evident that histone modifications are key players in the regulation of chromatin states and dynamics as well as in gene expression. Therefore, histone modifications and the enzymatic machinery that set them are crucial regulators that can control cellular proliferation, differentiation,... | |||
TMPH-03764 |
YAP1 Protein, Human, Recombinant (His)
YAP1-2gamma,YAP2L,YAP65 |
Human | P. pastoris (Yeast) |
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1,... | |||
TMPH-02843 |
NPY Protein, Mouse, Recombinant (hFc)
Pro-neuropeptide Y,Npy |
Mouse | P. pastoris (Yeast) |
NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | |||
TMPH-03720 |
YscM Protein, Yersinia enterocolitica, Recombinant (His & SUMO)
Yop proteins translocation protein M,yscM |
Yersinia enterocolitica | E. coli |
Belongs to an operon involved in the translocation of Yop proteins across the bacterial membranes or in the specific control of this function. | |||
TMPH-01276 |
ENOX1 Protein, Human, Recombinant (His)
Ecto-NOX disulfide-thiol exchanger 1,ENOX1,cNOX,cCNOX |
Human | E. coli |
Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 24 minutes and play a role in control of the ultradian cellular biological clock. | |||
TMPH-01278 |
ENOX2 Protein, Human, Recombinant (His & Myc)
Cytosolic ovarian carcinoma antigen 1,Ecto-NOX disulfide-thi... |
Human | E. coli |
May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 22 minutes and play a role in control of the ultradian cellular biol... | |||
TMPH-03726 |
YscM Protein, Yersinia pseudotuberculosis serotype I, Recombinant (His & SUMO)
Yop proteins translocation protein M,Low calcium response lo... |
Yersinia pseudotuberculosis | E. coli |
Belongs to an operon involved in the translocation of Yop proteins across the bacterial membranes or in the specific control of this function. | |||
TMPH-00722 |
PykF Protein, E. coli, Recombinant (His)
Pyruvate kinase I,PK-1,pykF |
E. coli | E. coli |
Catalyzes the formation of pyruvate in the last step of glycolysis, it is irreversible under physiological conditions. The reaction is critical for the control of metabolic flux in the second part of glycolysis. | |||
TMPH-01277 |
ENOX2 Protein, Human, Recombinant
ENOX2,APK1 antigen,Cytosolic ovarian carcinoma antigen 1,COV... |
Human | E. coli |
May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 22 minutes and play a role in control of the ultradian cellular biol... | |||
TMPJ-00528 |
PPP1R1A Protein, Human, Recombinant (His)
PPP1R1A,I-1,IPP-1,Protein Phosphatase Inhibitor 1,Protein Ph... |
Human | E. coli |
Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen metabolism, IPP-1 protein plays important function. Hormones can elevate intracellular cAMP level and elevate IPP-1 activity. PPP1R1A activation caused cAMP increase , cAMP control over proteins that are not directly phosphorylated by PKA following a rise in intracellular calcium. IPP-1 is inactivated by cal... | |||
TMPH-03387 |
TSHB Protein, Rat, Recombinant (His & Myc)
Thyrotropin subunit beta,Thyroid-stimulating hormone subunit... |
Rat | P. pastoris (Yeast) |
Indispensable for the control of thyroid structure and metabolism. TSHB Protein, Rat, Recombinant (His & Myc) is expressed in yeast with N-6xHis and C-Myc tag. The predicted molecular weight is 16.4 kDa and the accession number is P04652. | |||
TMPH-03041 |
IHF-alpha Protein, MenB, Recombinant (His)
Integration host factor subunit alpha,ihfA |
MenB | E. coli |
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. | |||
TMPY-03049 |
GALNT10 Protein, Human, Recombinant (His)
GALNACT10,PPGANTASE10,polypeptide N-acetylgalactosaminyltran... |
Human | HEK293 Cells |
Ectopic expression and knockdown studies showed that GALNT10 indeed promotes proliferation and apoptosis resistance of hepatoma cells in a glycosyltransferase-dependent manner. The genetic variants on LEKR1 and GALNT10 genes have been associated with control of adiposity and weight. | |||
TMPH-02198 |
TXNRD2 Protein, Human, Recombinant (His & SUMO)
TR-beta,Thioredoxin reductase 2, mitochondrial,Thioredoxin r... |
Human | E. coli |
Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis. Maintains thioredoxin in a reduced state. May play a role in redox-regulated cell signaling. | |||
TMPH-02493 |
ADAMDEC1 Protein, Mouse, Recombinant (His)
A disintegrin and metalloproteinase domain-like protein decy... |
Mouse | E. coli |
May play an important role in the control of the immune response and during pregnancy. ADAMDEC1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 34.9 kDa and the accession number is Q9R0X2. | |||
TMPH-03386 |
TSHB Protein, Rat, Recombinant (E. coli, His & Myc)
Thyrotropin beta chain,Tshb,Thyrotropin subunit beta,Thyroid... |
Rat | E. coli |
Indispensable for the control of thyroid structure and metabolism. TSHB Protein, Rat, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 19.9 kDa and the accession number is P04652. | |||
TMPY-02259 |
FKBP25/FKBP3 Protein, Human, Recombinant (GST)
FKBP-25,PPIase,FKBP25,FK506 binding protein 3,FKBP-3 |
Human | E. coli |
FKBP3 is a member of FK506-binding proteins (FKBPs). miR-145-5p overexpression suppressed cell proliferation of NSCLC cells which was abrogated by FKBP3 overexpression, that FKBP3/Sp1/HDAC2/p27 control cell proliferation during NSCLC development. | |||
TMPK-00742 |
PRL-3/PTP4A3 Protein, Human, Recombinant (His)
PRL-R,PRLR,PRL3,PTP4A3,PRL-3 |
Human | E. coli |
Phosphatases of regenerating liver (PRL-1, PRL-2, and PRL-3, also known as PTP4A1, PTP4A2, and PTP4A3) control magnesium homeostasis through an association with the CNNM magnesium transport regulators. PTP4A3 (PRL-3) plays an important role in the tumorigenesis and metastasis of multiple tumors. | |||
TMPH-03042 |
IHF-beta Protein, MenB, Recombinant (His)
Integration host factor subunit beta,ihfB |
MenB | E. coli |
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. IHF-beta Protein, MenB, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 17.8 kDa and the accession number is P0A0U2. | |||
TMPH-00538 |
Epstein-Barr virus (strain GD1) EBNA3 Protein (His & Myc)
Epstein-Barr nuclear antigen 3A,Epstein-Barr nuclear antigen... |
EBV | E. coli |
Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop. | |||
TMPK-01132 |
PRL-1/PTP4A1 Protein, Human, Recombinant (His)
PTPCAAX1,PRL1,PRL-1,PTP(CAAXI),PTP4A1 |
Human | E. coli |
Phosphatases of regenerating liver (PRL-1, PRL-2, and PRL-3, also known as PTP4A1, PTP4A2, and PTP4A3) control magnesium homeostasis through an association with the CNNM magnesium transport regulators. PRL-1 (PTP4A1) is a key molecule that activates tyrosine phosphorylation, which is important for cancer progression and metastasis. | |||
TMPY-00140 |
ABP1/AOC1 Protein, Human, Recombinant (His)
amine oxidase, copper containing 1,DAO,ABP1,ABP,KAO,DAO1 |
Human | HEK293 Cells |
Amine oxidase copper-containing 1 (AOC1; formerly known as amiloride-binding protein 1) is a secreted glycoprotein that catalyzes the degradation of putrescine and histamine. Polyamines and their diamine precursor putrescine are ubiquitous to all organisms and fulfill pivotal functions in cell growth and proliferation. That the Wilms tumor protein, WT1, which is necessary for normal kidney development, activates transcription of the AOC1 gene. Expression of a firefly luciferase reporter under co... | |||
TMPK-00868 |
Notch 4 Protein, Mouse, Recombinant (His)
Notch-4,Int-3,Notch4,Int3 |
Mouse | HEK293 Cells |
The Notch signaling pathway is important for cell-cell communication; it is involved in gene regulation mechanisms that control multiple cell differentiation processes during embryonic and adult life. Notch-4 expression correlates with Ki67. Notch-4 also plays a key role in breast cancer stem-like cells. | |||
TMPJ-00057 |
REG3G Protein, Human, Recombinant (hFc)
PAP-1B,REG3G,Regenerating islet-derived protein III-γ,Regene... |
Human | HEK293 Cells |
Pancreatitis-associated protein IB, Regenerating islet-derived protein III-gamma, is a secreted protein which contains 1 C-type lectin domain. It is expressed almost exclusively in the pancreas and also expressed in testis, but not found in small intestine. This protein might be a stress protein involved in the control of bacterial proliferation. | |||
TMPH-00537 |
Epstein-Barr virus (strain B95-8) EBNA3 Protein (His & Myc)
Epstein-Barr nuclear antigen 3,EBNA3,Epstein-Barr nuclear an... |
EBV | E. coli |
Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop. | |||
TMPK-00403 |
SEMA4D Protein, Human, Recombinant (His & Avi)
CD100,FLJ34282,SEMA4D,Semaphorin-4D,coll-4,SEMAJ,MGC169141,C... |
Human | HEK293 Cells |
Semaphorin 4D (Sema4D) is a multifunctional protein widely expressed in an organism that plays an important role in the control of many physiological and pathological processes, including immunoregulation, neurogenesis, angiogenesis, and tumor progression. SEMA4D Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 82.1 kDa and the accession number is Q92854-1. | |||
TMPK-01379 |
SEMA4D Protein, Cynomolgus, Recombinant (His)
Semaphorin-4D,FLJ33485,FLJ46484,SEMA4D,FLJ39737,coll-4,FLJ34... |
Cynomolgus | HEK293 Cells |
Semaphorin 4D (Sema4D) is a multifunctional protein widely expressed in an organism that plays an important role in the control of many physiological and pathological processes, including immunoregulation, neurogenesis, angiogenesis, and tumor progression. SEMA4D Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 80.1 kDa and the accession number is A0A2K5TZC9. | |||
TMPY-06623 |
CB2/CNR2 Protein, Human, Recombinant
CB2,CB-2,CX5 |
Human | HEK293 Cells |
Genetic variants within the CNR2 gene encoding the cannabinoid receptor CB2 are associated with osteoporosis and low bone mineral density (BMD) in case-control studies. There is a possibility that genetic variants of the CNR1 gene may produce a liability to the complication of psychotic state after abuse of methamphetamine. | |||
TMPJ-00625 |
Serpin E1 Protein, Mouse, Recombinant (His)
Pai1,Planh1,Plasminogen activator inhibitor 1,Serpin E1,Mr1,... |
Mouse | HEK293 Cells |
Plasminogen activator inhibitor-1 (serpin E1) is a serine protease inhibitor which belongs to the serpin family. Serpin E1 acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis. | |||
TMPK-00404 |
SEMA4D Protein, Human, Recombinant (His & Avi), Biotinylated
FLJ39737,CD100,SEMAJ,C9orf164,FLJ34282,M-sema-G,FLJ46484,Sem... |
Human | HEK293 Cells |
Semaphorin 4D (Sema4D) is a multifunctional protein widely expressed in an organism that plays an important role in the control of many physiological and pathological processes, including immunoregulation, neurogenesis, angiogenesis, and tumor progression. SEMA4D Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 82.1 kDa and the accession number is Q92854-1. | |||
TMPJ-01385 |
CLEC4E Protein, Human, Recombinant (His)
C-Type Lectin Superfamily Member 9,CLEC4E,C-Type Lectin Doma... |
Human | HEK293 Cells |
C-Type Lectin Domain Family 4 Member E (CLEC4E) is a 219 amino acid single-pass type II membrane protein that contains one C-type Lectin domain. It is expressed in monocytes, CLEC4E functions as a downstream target of C/EBP β and is thought to play a role in the inflammatory response, possibly via transcriptional control of C/EBP β. CLEC4E may play a role in the response to inflammatory stimuli in peritoneal macrophages and may be involved in immune surveillance processes under transcriptional c... | |||
TMPH-00304 |
SV2A Protein, Bovine, Recombinant (His & Myc)
Synaptic vesicle glycoprotein 2A,p87,SV2A |
Bovine | HEK293 Cells |
Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles. SV2A Protein, Bovine, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 22.8 kDa and the accession number is Q29397. | |||
TMPH-01798 |
Nucleolar transcription factor 1 Protein, Human, Recombinant (Cell-Free, His & SUMO)
Nucleolar transcription factor 1,Upstream-binding factor 1,U... |
Human | E. coli |
Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element. Nucleolar transcription factor 1 Protein, Human, Recombinant (Cell-Free, His & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO tag. The predicted molecular weight is 107.9 kDa and the accession number is P17480. | |||
TMPH-01799 |
Nucleolar transcription factor 1 Protein, Human, Recombinant (E. coli, His & SUMO)
Nucleolar transcription factor 1,Autoantigen NOR-90,UBTF,Ups... |
Human | E. coli |
Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element. Nucleolar transcription factor 1 Protein, Human, Recombinant (E. coli, His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 95.2 kDa and the accession number is P17480. | |||
TMPJ-01245 |
UCMA Protein, Human, Recombinant
UCMA,Unique cartilage matrix-associated protein,Gla-rich pro... |
Human | E. coli |
C10orf49 is a secreted protein which encoded by the UCMA gene. It is a member of the UCMA family. C10orf49 is predominantly expressed in resting chondrocytes. It may be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface. | |||
TMPH-00893 |
AHCY Protein, Human, Recombinant (His & SUMO)
AdoHcyase,S-adenosyl-L-homocysteine hydrolase,SAHH,Adenosylh... |
Human | E. coli |
Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine. AHCY Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 63.6 kDa and the accession number is P23526. | |||
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Cat. No. | Product Name | Target | Signaling Pathways |
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TMIJ-0246 |
Tetracaine-d6
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Tetracaine-d6 是 Tetracaine 的氘代化合物。Tetracaine 的 CAS 号为 94-24-6。 | |||
TMIJ-0479 |
Dicamba-d3 (methoxy-d3)
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Dicamba-d3 (methoxy-d3) 是 Dicamba 的氘代化合物。Dicamba 的 CAS 号为 1918-00-9。Dicamba 是一种氯化有机除草剂。 Dicamba 可用于防治阔叶杂草。 | |||
TMIJ-0490 |
Azamethiphos-d6
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Azamethiphos-d6 是 Azamethiphos 的氘代化合物。Azamethiphos 的 CAS 号为 35575-96-3。Azamethiphos 是有机磷杀虫剂和神经毒性物质,能够抑制乙酰胆碱酯酶的活性。 | |||
TMIJ-0486 |
Diazinon-d10
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Diazinon-d10 是 Diazinon 的氘代化合物。Diazinon 的 CAS 号为 333-41-5。Diazinon是硫代磷酸酯, 是一种非系统性有机磷杀虫剂,用于防治蟑螂、银鱼、蚂蚁和跳蚤。 | |||
TMIJ-0467 |
Dimethoate-d6 (O,O dimethyl-d6)
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Dimethoate-d6 (O,O dimethyl-d6) 是 Dimethoate 的氘代化合物。Dimethoate 的 CAS 号为 60-51-5。Dimethoate 是一种系统性和接触性杀虫剂,用于控制牛蛴螬和农场动物的某些其他害虫。 | |||
TMIJ-0476 |
Chlorotoluron-d6 (N,N-dimethyl-d6)
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Chlorotoluron-d6 (N,N-dimethyl-d6) 是 Chlorotoluron 的氘代化合物。Chlorotoluron 的 CAS 号为 15545-48-9。Chlorotoluron 是取代的苯基脲除草剂,普遍用于谷物作物的选择性杂草控制,是环境污染物。 | |||
TMIJ-0516 |
Carbaryl-d3
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Carbaryl-d3 是 Carbaryl 的氘代化合物。Carbaryl 的 CAS 号为 63-25-2。Carbaryl 可作为一种杀虫剂。 | |||
TMID-0048 |
Dinotefuran-d3
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Dinotefuran-d3 是 Dinotefuran 的氘代化合物。Dinotefuran 的 CAS 号为 165252-70-0。Dinotefuran是一种新型烟碱类杀虫剂, 通过抑制烟碱乙酰胆碱受体而破坏昆虫的神经系统起作用。 | |||
TMIH-0146 |
Chloroquine-d5
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Chloroquine-d5 是 Chloroquine 的氘代化合物。Chloroquine 的 CAS 号为 54-05-7。Chloroquine 是一种自噬和 Toll 样受体抑制剂。 氯喹是一种抗疟疾和抗炎剂,广泛用于治疗疟疾和类风湿性关节炎。它在体外控制 SARS-CoV-2 (COVID-19) 感染方面非常有效,EC50 为 1.13 μM。 | |||
TMIJ-0417 |
2,4-D-d3
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2,4-D-d3 是 2,4-D 的氘代化合物。2,4-D 的 CAS 号为 94-75-7。2,4-Dichlorophenoxyacetic acid 是一种合成生长素,用作植物生长调节剂,也用作植物细胞培养基中的补充剂。它是除草剂中的一种活性成分,用于破坏肌动蛋白细胞骨架,以控制根系伸长和细胞生成。 |