GSK9311

产品编号 T13715LCas号 1923851-49-3

别名

GSK9311 inhibits BRPF bromodomain (pIC50: 6.0 and 4.3 for BRPF1 and BRPF2, respectively). GSK9311 is a less active analog of GSK6853. It can be used as a negative control.

GSK9311

产品编号 T13715LCas号 1923851-49-3

GSK9311 inhibits BRPF bromodomain (pIC50: 6.0 and 4.3 for BRPF1 and BRPF2, respectively). GSK9311 is a less active analog of GSK6853. It can be used as a negative control.

规格	价格	库存	数量
2 mg	¥ 447	5日内发货
5 mg	¥ 859	5日内发货

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产品介绍

生物活性

产品描述	GSK9311 inhibits BRPF bromodomain (pIC50: 6.0 and 4.3 for BRPF1 and BRPF2, respectively). GSK9311 is a less active analog of GSK6853. It can be used as a negative control.
靶点活性	BRPF1:6.0 (pic50), BRPF2:4.3 (pic50)
体外活性	GSK6853 is a less active analogue of GSK6853 in which the 5-amide is alkylated. GSK6853 is a potent (300 pM), soluble, cell active (20 nM), and highly selective inhibitor of the BRPF1 bromodomain. GSK6853 shows properties suitable for cellular and in vivo studies[1].

化学信息

分子量	437.53
分子式	C₂₄H₃₁N₅O₃
CAS No.	1923851-49-3

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

溶解度信息

DMSO: 30 mg/mL (68.57 mM)

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2856 mL	11.4278 mL	22.8556 mL	114.2779 mL
5 mM	0.4571 mL	2.2856 mL	4.5711 mL	22.8556 mL
10 mM	0.2286 mL	1.1428 mL	2.2856 mL	11.4278 mL
20 mM	0.1143 mL	0.5714 mL	1.1428 mL	5.7139 mL
50 mM	0.0457 mL	0.2286 mL	0.4571 mL	2.2856 mL