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TMPH-00003
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LASP1 Protein, Human, Recombinant (His)
LIM and SH3 domain protein 1,Metastatic lymph node ...
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Human
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P. pastoris (Yeast)
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LASP1 Protein, Human, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 31.2 kDa; 43 kDa, reducing conditions and the accession number is Q14847. |
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TMPJ-00778
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HER2/ERBB2 Protein, Human, Recombinant (His)
TKR1,Metastatic lymph node gene 19 protein,ERBB2,Pr...
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Human
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HEK293 Cells
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HER2/ERBB2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 90-120 KDa and the accession number is P04626. |
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TMPJ-00776
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HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Tyrosine kinase-type cell surface receptor HER2,NGL,EGFR2,TK...
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Human
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HEK293 Cells
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HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 120-140 KDa and the accession number is P04626. |
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TMPJ-00777
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HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc)
TKR1,Proto-oncogene Neu,EGFR2,Tyrosine kinase-type cell surf...
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Human
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HEK293 Cells
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HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 120-145 KDa and the accession number is P04626. |
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TMPY-02030
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CD82 Protein, Human, Recombinant (His)
CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,TSPAN27,ST6,IA4,GR1...
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Human
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HEK293 Cells
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CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud... |
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TMPY-04722
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DcR1/TRAILR3 Protein, Human, Recombinant (His)
TRAILR3,TRID,DCR1,TRAIL-R3,CD263,DCR1-TNFR,tumor necrosis fa...
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Human
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HEK293 Cells
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TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most PC cell lines (except CFPAC-1). Inactivation of TNFRSF10C by CpG island (CGI) hypermethylation can play an important role in PC progression and be potentially useful as a diagnostic marker and a new therapeutic approach for PC. |
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TMPY-04830
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GAS6 Protein, Mouse, Recombinant (His)
growth arrest-specific 6,Gas-6
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Mouse
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HEK293 Cells
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The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin K-dependent protein, plays a role in the survival, proliferation, migration, differentiation, adhesion, and apoptosis of cells. The growth arrest-specific 6 (GAS6) has been implicated in systemic inflammation and coagulation. Growth arrest-specific 6 (GAS6), plays a role in tumor... |
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TMPK-01299
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CEACAM5 Protein, Cynomolgus, Recombinant (aa 35-685, His)
Carcinoembryonic,CEA,CEACD66e,DKFZp781M2392,CEACAM-5,CD66e,M...
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Cynomolgus
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HEK293 Cells
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Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver. CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites. Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors, and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated. |
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TMPY-03876
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PTGFRN Protein, Cynomolgus, Recombinant (His)
prostaglandin F2 receptor inhibitor
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Cynomolgus
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HEK293 Cells
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EWI-F, also known as PTGFRN, is inversely related to the loss of CD9. Its expression correlates with the metastatic status of hLT. EWI-F inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. EWI-F expression positively correlates with the metastatic status of hLT, and that the upregulation of EWI-F expression could be one of the mechanisms underlying the loss of CD9 in solid tumours. |
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TMPY-02622
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Aldolase B Protein, Human, Recombinant (GST)
aldolase B, fructose-bisphosphate,ALDO2,ALDB
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Human
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E. coli
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The aldolase family members involved in metabolism and glycolysis are present in three isoforms: ALDOA, ALDOB, and ALDOC. Aldolases are differentially expressed in human tissues, and aberrant expression has been observed in several human diseases and cancer types. Via GATA6, metastatic cells in the liver upregulate the enzyme aldolase B (ALDOB), which enhances fructose metabolism and provides fuel for major pathways of central carbon metabolism during tumor cell proliferation. Targeting ALDOB or... |
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TMPY-01122
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CGB5 Protein, Human, Recombinant (mFc)
HCG,hCGB,chorionic gonadotropin beta subunit 5,chorionic gon...
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Human
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HEK293 Cells
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The human CGB5 gene encodes chorionic gonadotropin (hCG)beta 5, which is aberrantly expressed in trophoblastic neoplasm and in some non-trophoblastic neoplasms. Fucntional studies observed that it involved tumor initiation, growth, and metastatic outgrowth. Carriage of particular variants in the promoter of the CGB5 gene seems to protect against RM. CGB5 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 41.9 kDa and the acces... |
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TMPK-01182
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CDCP1 Protein, Human, Recombinant (hFc)
CDCP1,PRO5773,TRASK,UNQ2486,SIMA135,CD318
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Human
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HEK293 Cells
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Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression. CDCP1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 98.4 kDa and the accession number is Q9H5V8-1. |
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TMPK-01181
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CDCP1 Protein, Human, Recombinant (His & Avi), Biotinylated
CDCP1,PRO5773,TRASK,UNQ2486,SIMA135,CD318
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Human
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HEK293 Cells
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Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression. CDCP1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 74.6 kDa and the accession number is Q9... |
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TMPK-01255
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CDCP1 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
TRASK,SIMA135,UNQ2486,PRO5773,CD318,CDCP1
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Cynomolgus
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HEK293 Cells
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Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression. CDCP1 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 75 kDa and the accession number is... |
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TMPY-05250
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CLEC3A Protein, Mouse, Recombinant (His)
C-type lectin domain family 3, member A,Gm796,1110019O10Rik,...
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Mouse
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Baculovirus Insect Cells
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C-type lectin domain family 3 member A (CLEC3A) is a poorly characterized protein belonging to the superfamily of C-type lectins. Elevated CLEC3A expression may correlate with breast IDC metastatic potential and indicated a poor prognosis in breast IDC. CLEC3A knockdown inhibited BC cell growth and metastasis might be through suppressing PI3K/AKT signaling activity. That CLEC3A is a promising therapeutic target for BC in the future. Matrilysin (MMP-7) plays important roles in tumor progression. ... |
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TMPK-00593
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Syndecan-1 Protein, Human, Recombinant (His & Avi), Biotinylated
Syndecan-1,CD138,SDC1,SYND1,SDC
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Human
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HEK293 Cells
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Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteoglycans in the liver. Syndecan-1 is normally expressed on the surfaces of hepatocytes and cholangiocytes. Due to liver diseases the amount of syndecan-1 increases in the liver. Syndecan-1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.8 ... |
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TMPK-00635
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CDCP1 Protein, Rat, Recombinant (His)
TRASK,SIMA135,UNQ2486,CD318,PRO5773,CDCP1
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Rat
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HEK293 Cells
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Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression. CDCP1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 73.09 kDa and the accession number is D3ZVA1. |
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TMPK-01256
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CDCP1 Protein, Cynomolgus, Recombinant (His)
TRASK,SIMA135,UNQ2486,CD318,PRO5773,CDCP1
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Cynomolgus
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HEK293 Cells
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Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression. CDCP1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 73.2 kDa and the accession number is F6TPM5. |
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TMPK-00595
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Syndecan-1 Protein, Human, Recombinant (aa 23-254, His)
Syndecan-1,CD138,SDC,SYND1,SDC1
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Human
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HEK293 Cells
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Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteoglycans in the liver. Syndecan-1 is normally expressed on the surfaces of hepatocytes and cholangiocytes. Due to liver diseases the amount of syndecan-1 increases in the liver. Syndecan-1 Protein, Human, Recombinant (aa 23-254, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 25 kDa and the acc... |
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TMPJ-00786
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ITGB1 Protein, Human, Recombinant (aa 21-728, His)
Integrin Beta-1,VLA-4 Subunit β,Fibronectin Receptor Subunit...
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Human
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HEK293 Cells
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Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. ITGB1 is an integrin unit associated with very late antigen receptors, which contains one VWFA domain. It is known to conjoin with α-3 subunit to create α3β1 complex that reacts to such molecules as netrin-1 and ree... |
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TMPK-01010
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CDCP1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
UNQ2486,TRASK,CD318,SIMA135,CDCP1,PRO5773
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Mouse
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HEK293 Cells
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Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression. CDCP1 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 75.3 kDa and the accession number is Q5... |
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TMPK-01183
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CDCP1 Protein, Human, Recombinant (aa 30-368, His)
CDCP1,PRO5773,TRASK,CD318,UNQ2486,SIMA135
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Human
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HEK293 Cells
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Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression. CDCP1 Protein, Human, Recombinant (aa 30-368, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 39.03 kDa and the accession number is Q9H5V8-1. |
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TMPY-02384
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MTSS1 Protein, Human, Recombinant (aa1-250, His & MBP)
metastasis suppressor 1,MIMB,MIM,MIMA
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Human
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E. coli
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MTSS1 (Metastasis suppressor 1), also known as Missing in metastasis (MIM), is a tissue-specific regulator of plasma membrane dynamics. MTSS1 is well described for its function as a metastasis suppressor gene and is expressed in a variety of tissues. MTSS1 might be involved in shaping neuronal membranes in vivo. MTSS1 deforms phosphoinositide-rich membranes through its I-BAR domain and interacts with actin monomers through its WH2 domain. MTSS1/MIM was first identified as a metastasis suppressor... |
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TMPK-01284
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Syndecan-1 Protein, Cynomolgus, Recombinant (His)
Syndecan-1,SYND1,SDC1,CD138,SDC
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Cynomolgus
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HEK293 Cells
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Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteoglycans in the liver. Syndecan-1 is normally expressed on the surfaces of hepatocytes and cholangiocytes. Due to liver diseases the amount of syndecan-1 increases in the liver. Syndecan-1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 24.97 kDa and the access... |
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TMPY-03982
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CGB5 Protein, Human, Recombinant (His)
chorionic gonadotropin beta subunit 5,HCG,chorionic gonadotr...
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Human
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HEK293 Cells
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The human CGB5 gene encodes chorionic gonadotropin (hCG)beta 5, which is aberrantly expressed in trophoblastic neoplasm and in some non-trophoblastic neoplasms. Fucntional studies observed that it involved tumor initiation, growth, and metastatic outgrowth. Carriage of particular variants in the promoter of the CGB5 gene seems to protect against RM. CGB5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17 kDa and the accessi... |
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TMPK-00594
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Syndecan-1 Protein, Human, Recombinant (aa 23-254, hFc)
CD138,SDC1,SYND1,Syndecan-1,SDC
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Human
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HEK293 Cells
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Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteoglycans in the liver. Syndecan-1 is normally expressed on the surfaces of hepatocytes and cholangiocytes. Due to liver diseases the amount of syndecan-1 increases in the liver. Syndecan-1 Protein, Human, Recombinant (aa 23-254, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 50.6 kDa and the a... |
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TMPK-00201
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Syndecan-1 Protein, Mouse, Recombinant (hFc)
Syndecan-1,CD138,SDC,SDC1,SYND1
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Mouse
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HEK293 Cells
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Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still a major medical challenge. Syndecan-1 is one of the most important proteoglycans in the liver. Syndecan-1 is normally expressed on the surfaces of hepatocytes and cholangiocytes. Due to liver diseases the amount of syndecan-1 increases in the liver. Syndecan-1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 51 kDa and the accession numb... |
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TMPK-00906
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PSCA Protein, Mouse, Recombinant (hFc)
UNQ206,PSCA,PRO232
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Mouse
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HEK293 Cells
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Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell surface protein widely expressed in bladder, prostate, and pancreatic cancers. Existing studies have thoroughly recognized the availability of utilizing anti-PSCA CAR-T cells in the treatment of metastatic prostate cancer and non-small-cell lung cancer. PSCA Protein, Mouse, Recomb... |
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TMPK-00728
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PSCA Protein, Human, Recombinant (hFc)
UNQ206,PRO232,PSCA
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Human
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HEK293 Cells
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Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell surface protein widely expressed in bladder, prostate, and pancreatic cancers. Existing studies have thoroughly recognized the availability of utilizing anti-PSCA CAR-T cells in the treatment of metastatic prostate cancer and non-small-cell lung cancer. PSCA Protein, Human, Recomb... |
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TMPY-03047
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Stathmin 1 Protein, Human, Recombinant (His)
SMN,OP18,stathmin 1,LAP18,C1orf215,PP17,Lag,PP19,PR22
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Human
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E. coli
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Stathmin1 (STMN1) is a cytosolic phosphoprotein that regulates cellular microtubule dynamics and is known to have oncogenic activity. STMN1 is a possible biomarker for paclitaxel sensitivity and poor prognosis in GC and could be a novel therapeutic target in metastatic GC. STMN1 expression might serve as a biomarker for determining patient atypical meningioma prognosis. Stathmin1 (STMN1) is a cytosolic protein involved in microtubule dynamics through inhibition of tubulin polymerization and prom... |
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TMPY-04765
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PKLR Protein, Human, Recombinant (His)
PKRL,PKR,RPK,PKL,PK1,pyruvate kinase, liver and RBC
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Human
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E. coli
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Pyruvate kinase (PKLR) is a critical erythrocyte enzyme that is required for glycolysis and production of ATP. Pyruvate kinase deficiency (PKD) is the most frequent red blood cell enzyme abnormality of the glycolytic pathway and the most common cause of hereditary nonspherocytic hemolytic anemia. Over 250 PKLR-gene mutations have been described, including missense/nonsense, splicing and regulatory mutations, small insertions, small and gross deletions, causing PKD and hemolytic anemia of variabl... |
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TMPY-04203
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RAB1B Protein, Human, Recombinant (hFc)
RAB1B, member RAS oncogene family
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Human
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HEK293 Cells
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RAB1B, a member of the RAS oncogene family, was significantly down-regulated in highly metastatic breast cancer cells. Moreover, down-regulation of RAB1B was also found to promote the proliferation and migration of TNBC cells in vitro and in vivo. Mechanistically, loss of RAB1B resulted in elevated expression of TGF-beta receptor 1 (TbetaR1) through decreased degradation of ubiquitin, increased levels of phosphorylated SMAD3 and TGF-beta-induced epithelial-mesenchymal transition (EMT). Furthermo... |
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TMPJ-00157
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CD82 Protein, Human, Recombinant (hFc)
Tetraspanin-27,KAI1,ST6,TSPAN27,TSPAN274F9,CD82 molecule,Tsp...
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Human
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HEK293 Cells
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CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1... |
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TMPY-02276
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GPR56 Protein, Human, Recombinant (His)
BFPP,UNQ540/PRO1083,DKFZp781L1398,TM7LN4,adhesion G protein-...
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Human
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HEK293 Cells
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ADGRG1 (Adhesion G Protein-Coupled Receptor G1, also known as GPR56) is a Protein Coding gene. GPR56 is a member of an adhesion G protein-coupled receptor family with a very long N-terminal stalk and seven transmembrane domains. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. GPR56 may be a target for the treatment of type 2 diabetes. GPR56 inhibits melanoma metastatic growth by impeding the exp... |
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TMPJ-01137
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MIA Protein, Human, Recombinant (His)
MIA,Melanoma Inhibitory Activity Protein,Melanoma-Derived Gr...
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Human
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E. coli
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Melanoma Inhibitory Activity Protein (MIA) is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells, which was the first discovered member of a family of secreted cytokines termed the MIA/OTOR family. The four known members of this family: MIA, MIA2, OTOR and TANGO each contain a Src homology-3 (SH3)-like domain. MIA acts as a potent tumor cell growth inhibitor for malignant melanoma cells and some other neuroectodermal tumors, including gliomas, in an au... |
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TMPY-01595
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PCBP1 Protein, Human, Recombinant (His)
HNRPE1,hnRNP-E1,HEL-S-85,HNRPX,poly(rC) binding protein 1,hn...
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Human
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E. coli
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Poly(rC)-binding protein 1, also known as Heterogeneous nuclear ribonucleoprotein E1, Alpha-CP1, Nucleic acid-binding protein SUB2.3 and PCBP1, is a family member of heterogeneous nuclear ribonucleoproteins (hnRNPs) that belong to RNA-binding proteins and bear three KH domains. PCBP1 is loosely bound in the nucleus. It may shuttle between the nucleus and the cytoplasm. It is abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in pr... |
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TMPY-02386
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PTP4A2 Protein, Human, Recombinant (GST)
HNMT-S2,PRL-2,HNMT-S1,protein tyrosine phosphatase type IVA,...
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Human
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E. coli
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PRL-2 (Protein-tyrosine phosphatase of regenerating liver 2), also known as PTP4A2 (Protein tyrosine phosphatase type IVA, member 2), is a member of PTP family and has an important function in controlling cell growth. PRL-2 phosphatases may be multifunctional enzymes with diverse roles in a variety of tissue and cell types. The phosphatase of regenerating liver (PRL) family, comprising PRL-1, PRL-2 and PRL-3, is a group of prenylated phosphatases that are candidate cancer biomarkers and therapeu... |
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