|
TMPY-03221
|
Intrinsic Factor Protein, Human, Recombinant (His)
IF,IFMH,gastric intrinsic factor (vitamin B synthes...
|
Human
|
HEK293 Cells
|
|
Gastric intrinsic factor, also known as GIF, belongs to the of the cobalamin transport protein family. It is a glycoprotein produced by the parietal cells of the stomach. Gastric intrinsic factor plays a key role in the absorption of vitamin B12 on in the small intestine. Vitamin B12 bounds to haptocorrin after entry into the stomach. The resulting complex enters the duodenum, where pancreatic enzymes digest haptocorrin. In the less acidic environment of the small intestine, B12 can then bind to... |
|
TMPY-00319
|
GIP Protein, Human, Recombinant (hFc)
gastric inhibitory polypeptide,GIP
|
Human
|
HEK293 Cells
|
|
Glucose-dependent insulinotropic polypeptide (GIP) is an incretin that plays an important role in fat accumulation. GIP is involved in fat accumulation and insulin resistance with aging. Glucose-dependent insulinotropic polypeptide (GIP) is an intestinal hormone with a broad range of physiological actions. Elevated concentrations of the incretin hormone GIP are found in patients with atherosclerotic cardiovascular disease, while GIP treatment attenuates atherosclerotic plaque inflammation in mi... |
|
TMPY-04079
|
LIPF Protein, Human, Recombinant (His)
GL,HLAL,lipase, gastric,HGL
|
Human
|
Baculovirus Insect Cells
|
|
LIPF Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 44.6 kDa and the accession number is AAI12273.1. |
|
TMPH-01377
|
GIPR Protein, Human, Recombinant (His)
GIPR,Glucose-dependent insulinotropic polypeptide receptor,<...
|
Human
|
E. coli
|
|
This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. GIPR Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.5 kDa and the accession number is P48546. |
|
TMPH-01378
|
GIPR Protein, Human, Recombinant (His & Myc)
GIPR,Glucose-dependent insulinotropic polypeptide receptor,<...
|
Human
|
HEK293 Cells
|
|
This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. GIPR Protein, Human, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 18.5 kDa and the accession number is P48546. |
|
TMPH-02672
|
GIPR Protein, Mouse, Recombinant (His & Myc)
Gastric inhibitory polypeptide receptor,Glucose-dep...
|
Mouse
|
E. coli
|
|
This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. |
|
TMPH-01892
|
ATP4A Protein, Human, Recombinant (His & Myc)
ATP4A,Gastric H(+)/K(+) ATPase subunit alpha,Potass...
|
Human
|
E. coli
|
|
ATP4A Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 54.6 kDa and the accession number is P20648. |
|
TMPJ-01061
|
Nucleobindin-2 Protein, Human, Recombinant
NUCB2,NEFA,Gastric cancer antigen Zg4,Nesfatin-1,Pr...
|
Human
|
E. coli
|
|
Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin2 (NUCB2). Nesfatin-1 is a neuropeptide produced in the hypothalamus of mammals. It participates in the regulation of hunger and fat storage. Nesfatin-1 is also expressed in other areas of the brain, and in pancreatic islets β-cells, gastric endocrine cells and adipocytes. Nesfatin-1 suppresses food intake and can regulate energy metabolism in a Leptin independent manner. Nesfatin-1 may ... |
|
TMPJ-00320
|
AMIGO2 Protein, Human, Recombinant (hFc)
DEGA,AMIGO-2,AMIGO2,ALI1,Alivin-1,Amphoterin-Induced Protein...
|
Human
|
HEK293 Cells
|
|
Amphoterin-Induced Protein 2 (AMIGO2) is a single-pass type I membrane protein which belongs to the AMIGO family of immunoglobulin superfamily. Mature AMIGO2 contains an Ig-like C2-type (immunoglobulin-like) domain, 6 LRR (leucine-rich) repeats, a LRRCT domain, as well as a LRRNT domain. AMIGO2 is mainly expressed in in breast, ovary, cervix, and uterus, although lower in lung, colon, and rectum. AMIGO2 required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2... |
|
TMPH-01893
|
ATP4B Protein, Human, Recombinant (GST)
Proton pump beta chain,Gastric H(+)/K(+) ATPase sub...
|
Human
|
E. coli
|
|
ATP4B Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 53.6 kDa and the accession number is P51164. |
|
TMPH-01894
|
ATP4B Protein, Human, Recombinant
Proton pump beta chain,Potassium-transporting ATPase subunit...
|
Human
|
E. coli
|
|
ATP4B Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 26.6 kDa and the accession number is P51164. |
|
TMPJ-00953
|
ADH7 Protein, Human, Recombinant (His)
Retinol Dehydrogenase,Alcohol Dehydrogenase Class 4 μ/σ Chai...
|
Human
|
HEK293 Cells
|
|
Alcohol dehydrogenase class 4 mu/sigma chain (ADH7) is a cytoplasm enzyme which is a member of the alcohol dehydrogenase family. The expression of this gene makes it much more abundant in the stomach than the liver, thus it differs from the other known gene family members. ADH7 may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good subst... |
|
TMPY-04779
|
BTN3A2 Protein, Human, Recombinant (His)
BTF3,BT3.2,BTF4,BTN3.2,CD277,butyrophilin subfamily 3 member...
|
Human
|
HEK293 Cells
|
|
The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A2 is overexpressed in gastric tumors, and deletion of BTN3A2 inhibited proliferation, migration, and invasion of gastric cancer cells. The butyrophilin 3 (BTN3) receptors are implicated in the T lymphocytes regulation and present a wide plasticity in mammals. A thorough phylogenetic analysis reveals a concerted... |
|
TMPY-02292
|
IGSF11 Protein, Human, Recombinant (His)
CT119,immunoglobulin superfamily, member 11,BT-IgSF,Igsf13,C...
|
Human
|
HEK293 Cells
|
|
Immunoglobulin superfamily member 11(IGSF11) is expressed on the plasma membrane in the testis and brain. These IGSF proteins undergo final modifications during capacitation and/or the acrosome reaction. IGSF proteins share significant homology with endothelial cell-selective adhesion molecule and coxsackievirus and adenovirus receptor, which mediates cell attachment and homotypic intercellular interactions. In clinical, the IGSF11 has been reported to overexpressed in colorectal cancers and hep... |
|
TMPY-01897
|
PRSS3 Protein, Human, Recombinant (His)
PRSS4,TRY4,TRY3,RP11-176F3.3,T9,MTG,protease, serine 3
|
Human
|
HEK293 Cells
|
|
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their ... |
|
TMPY-01442
|
DMBT1 Protein, Human, Recombinant (His)
GP340,deleted in malignant brain tumors 1,muclin
|
Human
|
HEK293 Cells
|
|
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are invo... |
|
TMPY-00150
|
IGF2/IGF-II Protein, Human, Recombinant
PP9974,胰岛素样生长因子,C11orf43,IGF-II,insulin-like growth factor 2
|
Human
|
P. pastoris (Yeast)
|
|
Insulin-like growth factor 2 (IGF-2/IGF-II) is a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumor, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. IGF-2/IGF-II is a mediator of prolactin-induced alveologenesis; prolactin, IGF-2, and cyclin D1, all of which are overexpressed in br... |
|
TMPK-00899
|
EPHA5 Protein, Human, Recombinant (His)
HEK7,EK7,Rek7,EphA5,EHK1,TYRO4HEK7CEK7,TYRO4,BSK,EHK-1
|
Human
|
HEK293 Cells
|
|
Ephrin type-A receptor 5 (EphA5) expression was detected in all non-tumor gastric epithelia but was differentially expressed among gastric cancer samples. EphA5 is differentially expressed in gastric cancer. EphA5 may therefore be a potential therapeutic target and may have clinical utility as a marker for lymph node metastasis in gastric cancer. EPHA5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 61.9 kDa and the acces... |
|
TMPK-00529
|
EPHA5 Protein, Cynomolgus, Recombinant (His)
EHK-1,BSK,Rek7,EK7,EphA5,HEK7,TYRO4,TYRO4HEK7CEK7,EHK1
|
Cynomolgus
|
HEK293 Cells
|
|
Ephrin type-A receptor 5 (EphA5) expression was detected in all non-tumor gastric epithelia but was differentially expressed among gastric cancer samples. EphA5 is differentially expressed in gastric cancer. EphA5 may therefore be a potential therapeutic target and may have clinical utility as a marker for lymph node metastasis in gastric cancer. EPHA5 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 61.73 kDa and the... |
|
TMPY-00519
|
Gastrokine 1 Protein, Human, Recombinant (His)
UNQ489/PRO1005,CA11,foveolin,BRICD1,AMP18,gastrokine 1,FOV
|
Human
|
Baculovirus Insect Cells
|
|
Gastrokine 1 (GKN1) belongs to the BRICHOS domain family and plays a major role in maintaining gastric mucosa integrity. GKN1 is highly expressed in gastric tissue and is secreted into the stomach but is not expressed in gastric cancer. GKN1-mediated inhibition of APP processing might represent a new approach for the prevention and therapy of Alzheimer's disease (AD). In the presence of GKN2, GKN1 loses its ability to decrease cell proliferation, induce apoptosis, and inhibit epigenetic alterati... |
|
TMPJ-01079
|
TFF2 Protein, Mouse, Recombinant (His)
SP,Trefoil Factor 2,Spasmolytic polypeptide,Tff2,Sml1
|
Mouse
|
HEK293 Cells
|
|
Recombinant Murine TFF-2 is an 11.9 kDa polypeptide of 106 amino acid residues, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds. The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility and gastric acid secretion. Recent data suggests a potential role for TFF2 in acute a... |
|
TMPK-01019
|
EPHA5 Protein, Mouse, Recombinant (His)
TYRO4,HEK7,EHK-1,EphA5,EK7,BSK,Rek7,EHK1,TYRO4HEK7CEK7
|
Mouse
|
HEK293 Cells
|
|
The aim of the present study was to evaluate ephrin type-A receptor 5 (EphA5) expression and its clinicopathological significance in gastric cancer. Gastric cancer tissues were analyzed by immunohistochemistry. The association between EphA5 expression and clinicopathological parameters, human epidermal growth factor receptor 2 (HER2) status and Ki-67 proliferation index was statistically analyzed. |
|
TMPH-00800
|
UreA Protein, Helicobacter pylori, Recombinant (His)
ureA,Urea amidohydrolase subunit alpha,Urease subunit alpha
|
Helicobacter pylori
|
P. pastoris (Yeast)
|
|
Ammonia produced by ureolysis increases the gastric pH thereby providing an environment permissive for colonization of the stomach. |
|
TMPK-01160
|
GPA34/VSIG1 Protein, Mouse, Recombinant (His)
dJ889N15.1,Glycoprotein A34,VSIG1,MGC44287,1700062D20Rik,Gpa...
|
Mouse
|
HEK293 Cells
|
|
VSIG1, a cell adhesion protein of the immunoglobulin superfamily, is preferentially expressed in stomach, testis, and certain gastric, esophageal and ovarian cancers. Here, we describe the expression patterns of three alternatively spliced isoforms of mouse Vsig1 during pre- and postnatal development of stomach and potential function of Vsig1 in differentiation of gastric epithelia. VSIG1 is required for the establishment of glandular versus squamous epithelia in the stomach. GPA34/VSIG1 Protein... |
|
TMPK-01076
|
GPA34/VSIG1 Protein, Human, Recombinant (His)
MGC44287,1700062D20Rik,Glycoprotein A34,VSIG1,Gpa34,dJ889N15...
|
Human
|
HEK293 Cells
|
|
VSIG1, a cell adhesion protein of the immunoglobulin superfamily, is preferentially expressed in stomach, testis, and certain gastric, esophageal and ovarian cancers. Here, we describe the expression patterns of three alternatively spliced isoforms of mouse Vsig1 during pre- and postnatal development of stomach and potential function of Vsig1 in differentiation of gastric epithelia. VSIG1 is required for the establishment of glandular versus squamous epithelia in the stomach. GPA34/VSIG1 Protein... |
|
TMPH-02298
|
Urocortin-3 Protein, Human, Recombinant (His & SUMO)
UCN3,Stresscopin,Urocortin III,Urocortin-3
|
Human
|
E. coli
|
|
Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress. |
|
TMPY-03979
|
ARHI Protein, Human, Recombinant (mFc)
DIRAS3,DIRAS family, GTP-binding RAS-like 3,ARHI,RHOI,NOEY2
|
Human
|
HEK293 Cells
|
|
ARHI, also known as DIRAS3, belongs to the small GTPase superfamily, Di-Ras family. ARHI gene is a novel tumor suppressor gene located on chromosome 1p31. Downregulation of ARHI expression has been detected in many types of cancer. ARHI is expressed in normal ovarian and breast epithelial cells but not in ovarian and breast cancers. As a suppressor, ARHI is not only an important factor in the pathogenesis of gastric cancer, but also a potential factor for tumor aggravation. ARHI expression in ga... |
|
TMPK-01093
|
Kremen-2 Protein, Mouse, Recombinant (His)
KRM2,KREMEN2,Dickkopf receptor 2,Kremen-2
|
Mouse
|
HEK293 Cells
|
|
Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/β-catenin signaling pathway. Compared to para-cancerous tissues, Krm2 was significantly up-regulated in gastric cancer tissues and was positively correlated with the pathological grade of gastric cancer patients. Krm2 can be a potent candidate for designing of targeted therapy. Kremen-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells ... |
|
TMPK-01106
|
Kremen-2 Protein, Human, Recombinant (His)
KRM2,KREMEN2,Kremen-2,Dickkopf receptor 2
|
Human
|
HEK293 Cells
|
|
Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/β-catenin signaling pathway. Compared to para-cancerous tissues, Krm2 was significantly up-regulated in gastric cancer tissues and was positively correlated with the pathological grade of gastric cancer patients. Krm2 can be a potent candidate for designing of targeted therapy. Kremen-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells ... |
|
TMPJ-01078
|
TFF2 Protein, Human, Recombinant (His)
SP,TFF2,Spasmolytic Polypeptide,Spasmolysin,SML1,Trefoil Fac...
|
Human
|
HEK293 Cells
|
|
Trefoil Factor 2 (TFF2) is a member of the trefoil family and contains two P-type (trefoil) domains. Members of this family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. TFF2 is a secreted protein and specifically expressed in the stomach. TFF2 inhibits gastrointestinal motility and gastric acid secretion. TFF2 could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in ... |
|
TMPH-00802
|
vacA Protein, Helicobacter pylori, Recombinant (His & SUMO)
Vacuolating cytotoxin autotransporter,vacA
|
Helicobacter pylori
|
E. coli
|
|
Induces vacuolation of eukaryotic cells. Causes ulceration and gastric lesions. vacA Protein, Helicobacter pylori, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 45.7 kDa and the accession number is Q48253. |
|
TMPJ-01089
|
TFF1 Protein, Mouse, Recombinant (His)
Bcei,Protein pS2,Ps2,Trefoil factor 1,Tff1
|
Mouse
|
HEK293 Cells
|
|
Trefoil Factor 1 (TFF1) belongs to the three structurally related secreted proteins that contain trefoil domains.TFF1 is an approximately peptide that has an important effect in epithelial regeneration and wound healing.It originates from musculus and highly expressed by goblet cells of the gastric and intestinal mucosa and by conjunctival goblet cells. TFF1 is a copper-binding protein that can form disulfide-linked homodimers, associate into disulfide-linked complexes with Gastrokine 2, and fo... |
|
TMPH-02522
|
GHRL Protein, Mouse, Recombinant (His)
Motilin-related peptide,Growth hormone-releasing peptide,Gro...
|
Mouse
|
E. coli
|
|
Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.; Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility. GHRL Protein, Mouse, Recombinant (His) is expressed in E. coli expre... |
|
TMPK-01304
|
Kremen-2 Protein, Cynomolgus, Recombinant (His)
KREMEN2,KRM2,Dickkopf receptor 2,Kremen-2
|
Cynomolgus
|
HEK293 Cells
|
|
Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/β-catenin signaling pathway. Compared to para-cancerous tissues, Krm2 was significantly up-regulated in gastric cancer tissues and was positively correlated with the pathological grade of gastric cancer patients. Krm2 can be a potent candidate for designing of targeted therapy. Kremen-2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian c... |
|
TMPH-00801
|
UreB Protein, Helicobacter pylori, Recombinant (His)
Urease subunit beta,Urea amidohydrolase subunit beta,ureB
|
Helicobacter pylori
|
E. coli
|
|
Ammonia produced by ureolysis increases the gastric pH thereby providing an environment permissive for colonization of the stomach. UreB Protein, Helicobacter pylori, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 65.7 kDa and the accession number is P69996. |
|
TMPH-00799
|
UreA Protein, Helicobacter pylori, Recombinant (E. coli, His)
Urea amidohydrolase subunit alpha,ureA,Urease subunit alpha
|
Helicobacter pylori
|
E. coli
|
|
Ammonia produced by ureolysis increases the gastric pH thereby providing an environment permissive for colonization of the stomach. UreA Protein, Helicobacter pylori, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 30.5 kDa and the accession number is P14916. |
|
TMPY-02581
|
STAT4 Protein, Human, Recombinant (His)
signal transducer and activator of transcription 4,SLEB11
|
Human
|
Baculovirus Insect Cells
|
|
High expression of STAT4 in gastric cancer predicted a better clinical outcome. STAT4 might be a useful biomarker to identify patients at high risk of recurrence after gastrectomy. Genetic variants in the transcription factor STAT4 are associated with increased susceptibility to systemic lupus erythematosus (SLE) and a more severe disease phenotype. |
|
TMPJ-00265
|
Serpin F1 Protein, Mouse, Recombinant
Pedf,Caspin,Stromal cell-derived factor 3,Sdf3,Pigment epith...
|
Mouse
|
E. coli
|
|
Serpin F1 is secreted Neurotrophic protein and belongs to the serpin family. Serpin F1 Highly expressed in the liver, gastric glandular mucosa and renal tubules. It is also expressed in the brain, heart, lung retina and testes. It induces extensive neuronal differentiation in retinoblastoma cells. It is potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, exhibits no serine protease inhibitory activi... |
|
TMPK-00743
|
LGR-5 Protein, Human, Recombinant (hFc)
G-protein coupled receptor HG38,G-protein coupled receptor 4...
|
Human
|
HEK293 Cells
|
|
G protein-coupled receptor 5 (LGR5), known as a stem cell marker for colon cancer and gastric cancer, can serve as a novel GSC marker involved in EMT and a therapeutic target in glioma.LGR5 is a new functional GSC marker and prognostic indicator that can promote EMT by activating the Wnt/β-catenin pathway and would thus be a novel therapeutic target for glioma. |
|
TMPJ-01028
|
Claudin-18.2 Protein, Human, Recombinant (Twin strep & Flag)
Claudin 18.2,CLDN18,Claudin-18,CLDN18.2,Claudin-18.2
|
Human
|
HEK293 Cells
|
|
Claudin-18 (CLDN18) is a protein that in humans is encoded by the CLDN18 gene. It belongs to the group of claudins. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. CLDN18 plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. CLDN18 has two isoform A1 and isoform A2. Human CLDN18.2 is highly expressed in a signifcant proportion of gastric and pancreat... |
|
TMPK-01152
|
CHRDL1 Protein, Human, Recombinant (His)
VOPT,Ventroptin,Neuralin-1,dA141H5.1,CHL,Chordin-like 1,CRDL...
|
Human
|
E. coli
|
|
CHRDL1 (Chordin-like 1) is a secreted protein that acts as an antagonist of bone morphogenetic protein (BMP). BMP plays a role as an activator of BMP receptor II (BMPR II), which mediates extracellular to intracellular signal transmission and is involved in carcinogenesis and metastasis.The hypermethylation of the CHRDL1 promoter in gastric cancer, which induced low expression of CHRDL1 and decreased its secretion to the supernatant. |
|
TMPK-00891
|
GIP Protein, Mouse, Recombinant (His)
GIP,Incretin
|
Mouse
|
HEK293 Cells
|
|
The potential application of glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide, GIP) in the management of obesity and type 2 diabetes has been controversial. Initial interest in the therapeutic use of GIP was dampened by evidence that its insulinotropic activity was reduced in type 2 diabetes and by reports that it increased glucagon secretion and adipose deposition in non-diabetic individuals. GIP Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cell... |
|
TMPK-00036
|
GIP Protein, Human, Recombinant (His)
Incretin,GIP
|
Human
|
HEK293 Cells
|
|
The potential application of glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide, GIP) in the management of obesity and type 2 diabetes has been controversial. Initial interest in the therapeutic use of GIP was dampened by evidence that its insulinotropic activity was reduced in type 2 diabetes and by reports that it increased glucagon secretion and adipose deposition in non-diabetic individuals. GIP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cell... |
|
TMPK-00890
|
GIP Protein, Mouse, Recombinant (hFc)
Incretin,GIP
|
Mouse
|
HEK293 Cells
|
|
The potential application of glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide, GIP) in the management of obesity and type 2 diabetes has been controversial. Initial interest in the therapeutic use of GIP was dampened by evidence that its insulinotropic activity was reduced in type 2 diabetes and by reports that it increased glucagon secretion and adipose deposition in non-diabetic individuals. GIP Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cell... |
|
TMPY-03795
|
EIF5A2 Protein, Human, Recombinant (His)
eIF5AII,eukaryotic translation initiation factor 5A2,EIF-5A2
|
Human
|
E. coli
|
|
Eukaryotic translation initiation factor 5A2 (EIF5A2) has been demonstrated to be upregulated in numerous types of human cancer and is associated with cancer progression. Silencing of EIF5A2 in the NSCLC cells resulted in the downregulation of the tumorigenic proteins, apoptosis regulator Bcl-2 and myc proto-oncogene protein, and upregulation of E-cadherin, suggesting that EIF5A2 promotes proliferation and metastasis through these proteins. EIF5A2 may therefore serve as a novel therapeutic targe... |
|
TMPK-00906
|
PSCA Protein, Mouse, Recombinant (hFc)
UNQ206,PSCA,PRO232
|
Mouse
|
HEK293 Cells
|
|
Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell surface protein widely expressed in bladder, prostate, and pancreatic cancers. Existing studies have thoroughly recognized the availability of utilizing anti-PSCA CAR-T cells in the treatment of metastatic prostate cancer and non-small-cell lung cancer. PSCA Protein, Mouse, Recomb... |
|
TMPK-00728
|
PSCA Protein, Human, Recombinant (hFc)
UNQ206,PRO232,PSCA
|
Human
|
HEK293 Cells
|
|
Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell surface protein widely expressed in bladder, prostate, and pancreatic cancers. Existing studies have thoroughly recognized the availability of utilizing anti-PSCA CAR-T cells in the treatment of metastatic prostate cancer and non-small-cell lung cancer. PSCA Protein, Human, Recomb... |
|
TMPJ-01288
|
KLF6 Protein, Human, Recombinant
CPBP,GC-Rich Sites-Binding Factor GBF,Suppressor of Tumorige...
|
Human
|
E. coli
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Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will resul... |
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TMPJ-01456
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Mucin-17/MUC17 Protein, Human, Recombinant (His)
Mucin-17, MUC-17, MUC17, MUC3, MUC-3
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Human
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HEK293 Cells
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Mucins are key components of the mucosal barrier in the stomach that protects epithelia from carcinogenic effects of chronic inflammation. Analysis of The Cancer Genome Atlas database indicated that mucin17 (MUC17) was more highly expressed in gastric cancer (GC) specimens, with favourable prognosis for patients. And that p38 signalling is a key factor involved in MUC17-mediated inhibition of GC cell proliferation and protection against inflammatory stimulation, MUC17 upregulates the expression ... |
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TMPJ-00500
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Kappa-Casein Protein, Human, Recombinant (His)
CSNK,Kappa-Casein,κ-Casein,CSN10,CASK,CSN3
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Human
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HEK293 Cells
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Kappa-Casein (CSN3) is a secreted protein that belongs to the Kappa-Casein family. CSN3 exists in heteromultimers that are composed of alpha-s 1casein and kappa casein linked by disulfide bonds. CSN3 is involved in a number of important physiological processes. In the gut, CSN3 protein is split into an insoluble peptide (para kappa-casein) and a soluble hydrophilic glycopeptide (caseinomacropeptide). Caseinomacropeptide is responsible for increased efficiency of digestion, prevention of neonat... |
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