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Targets Recommended: Integrin

157

抑制剂 & 化合物

137

天然产物

4

化合物库

65

重组蛋白

1

同位素标记化合物

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Cat. No. Product Name
L2640 神经保护化合物库

990 compounds
L6710 中药抗炎分子库

1246 compounds
1246 种具有抗炎活性或靶向炎症相关靶点的中药单体集合,是药物开发、药理研究的有效工具;
L6120 黄酮类天然产物库

514 compounds
514 种黄酮类天然产物的独特集合,可用于高通量筛选和高内涵筛选;
L7110 抗高血压化合物库

678 compounds
678 种高血压相关的小分子,用于高通量和高内涵筛选;

化合物库

神经保护化合物库
Cat.No: L2640
Compounds: 990
中药抗炎分子库
Cat.No: L6710
Compounds: 1246
黄酮类天然产物库
Cat.No: L6120
Compounds: 514
抗高血压化合物库
Cat.No: L7110
Compounds: 678
Cat. No. Product Name Target Signaling Pathways
T16695 Pyrintegrin

Integrin Cytoskeletal Signaling
Pyrintegrin 是一种 β1 整合素激动剂,也是 2,4-二取代的嘧啶,可促进胚胎干细胞存活。它可用作足细胞保护剂,能增强细胞-细胞外基质 (ECM) 粘附介导的整联蛋白信号传导,具有强大的成脂作用。
T2519 Lercanidipine

乐卡地平,Masnidipine

Calcium Channel Membrane transporter/Ion channel; Metabolism
Lercanidipine (Masnidipine) 是二氢吡啶类的钙通道阻滞剂,具有持久的降压作用和肾脏保护作用。
T5336 Zacopride hydrochloride

Potassium Channel; 5-HT Receptor GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
Zacopride hydrochloride 是5-HT3受体拮抗剂 (Ki:0.38 nM),也是5-HT4受体激动剂 (Ki:373 nM),具有抗焦虑作用。它对精神分裂症具有潜在的研究价值。
T0412 Idebenone

艾地苯醌,CV-2619

Apoptosis; Antioxidant; Mitochondrial Metabolism Apoptosis; Metabolism; oxidation-reduction
Idebenone (CV-2619) 是一种线粒体保护剂,具有神经保护功效,可用于研究阿尔茨海默病、亨廷顿舞蹈病,可透过血脑屏障,诱导细胞凋亡。
T0081 Lafutidine

拉呋替丁,FRG-8813

5-HT Receptor; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Lafutidine (FRG-8813) 是一种组胺受体 H2RA 拮抗剂,可抑制胃酸分泌,具有胃粘膜保护作用,可用于研究胃食管反流疾病。
T16812 RWJ-67657

JNJ 3026582

p38 MAPK MAPK
RWJ-67657 (JNJ 3026582) 是一种可口服的选择性p38α和p38β抑制剂,IC50分别为 1 和 11 μM。它是心脏保护剂,具有抗炎和抗肿瘤活性。
T6874 Lercanidipine hydrochloride

Corifeo,Carmen,Cardiovasc,乐卡地平盐酸盐,盐酸乐卡地平

Calcium Channel Membrane transporter/Ion channel; Metabolism
Lercanidipine hydrochloride (Corifeo) 是亲脂性二氢吡啶-钙通道阻滞剂,具有持久的降压作用和保护肾脏作用。
T6374 Alfacalcidol

Bondiol,Etalpha,阿法骨化醇,1-hydroxy Vitamin D3,1.alpha.-Hydroxyvitamin D3,1-hydroxycholecalciferol

Others Others
Alfacalcidol (Etalpha) 是一种维生素 D3 衍生物,是非选择性的维生素 D 受体活化剂,有用于骨质疏松研究的潜力。
T50107 Neuroprotective agent 1

Others Others
ethyl 2-[3,5-bis(trifluoromethyl)phenyl]-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate 是一种合成化合物,属于姜黄素家族。它通过抑制NF-κB 信号通路参与免疫反应和炎症的调节,通过激活Nrf2信号通路参与抗氧化反应的调节,通过抑制Akt 信号通路参与细胞存活和增殖的调节。
T6467 Cardioxane

ADR-529 Hydrochloride,ICRF-187 hydrochloride,ADR-529,右雷佐生盐酸盐,Dexrazoxane HCl,Cardioxane hydrochloride,ICRF-187

Topoisomerase DNA Damage/DNA Repair
Cardioxane (ADR-529) 是一种心脏保护剂。
T24840 STS-E412

STS E412,STSE412

Others Others
STS-E412 是一种具有组织保护性和选择性的 EPOR/CD131 受体激活剂,可用于研究神经系统疾病。
T21252 DHMB

2,3-Dihydroxy-4-Methoxybenzaldehyde

Others Others
DHMB (2,3-Dihydroxy-4-Methoxybenzaldehyde) 对肠上皮细胞发挥保护作用。 DHMB 具有抗炎和抗真菌能力。
T24821 Spizofurone

Espizofurona,AG-629

Others Others
Spizofurone (Espizofurona) 具有抗溃疡活性,对大鼠胃黏膜具有保护作用,可增加分离的牛蛙十二指肠粘膜中的碱性分泌。
T0259 Chromocarb

Chromone-2-carboxylic acid,色烯卡,Chromocarbe

Others Others
Chromocarb (Chromone-2-carboxylic acid) 是合成的血管保护剂。
T20109 Cystamine dihydrochloride

Others Others
Cystamine dihydrochloride 是一种辐射防护剂。它还可以防止四氯化碳肝损伤。
T31675 Esaprazole

C/63

Others Others
Esaprazole (C/63) 对人胃黏膜具有剂量依赖性的细胞保护作用。
T28655 Sabeluzole

R 58735,R58735,R-58735

Microtubule Associated Cytoskeletal Signaling
Sabeluzole (R-58735) 具有抗癫痫和增强认知的作用,抑制神经毒素诱导的tau表达和细胞死亡。Sabeluzole 对氯氮卓诱导的习惯障碍有保护作用,可用于研究阿尔茨海默症。
T1812 KX1-004

KX1 004,KX1004

Src Angiogenesis; Tyrosine Kinase/Adaptors
KX1-004 是非 ATP 竞争性 Src-PTK 抑制剂,IC50=40 μM。它能够保护耳蜗,使其免受有害噪音的影响,并防止噪音引起的听力损失 (NIHL)。
T26647 AR420626

AR 420626,AR-420626

Others Others
AR420626 是一种选择性脂肪酸 3 受体 (FA3R) 激动剂,对被选择性 FA3R 拮抗剂 β-羟基丁酸酯 (BHB) 完全阻断的猪甲酚 (SALS) 提供保护作用。
T20843 Aplodan

Nergize,Creatinolfosfate,磷酸肌肉醇,creatinol-O-phosphate,Creatinolfosfate, Creatinol Phosphate

Others Others
Aplodan (creatinol-O-phosphate) 表现出抗缺血和抗心律失常的能力以及对细胞膜的保护作用。 Aplodan 可用于缺血性心脏病或伴有持续性室性早搏的缺血性心脏病的研究。
T65816 Prolyl-4-hydroxylase Inhibitor 11

Others Others
Prolyl-4-hydroxylase Inhibitor 11 是一种新型脯氨酸4-羟化酶抑制剂,对普通小球藻(Chlorella vulgaris)氧化应激和 Cu(II)毒性的保护作用。
T8982 RH01687

Others Others
RH01687 是可以保护胰腺 β 细胞免受内质网应激诱导的细胞死亡的化合物。它对糖尿病具有潜在的研究价值。
T15049 Daltroban

BM-13505,SKF 96148

PPAR DNA Damage/DNA Repair; Metabolism
Daltroban (SKF 96148) (BM-13505) 是选择性和特异性的血栓素 A2 (TXA2) 受体拮抗剂。Daltroban 可以增加血管平滑肌细胞内钙。Daltroban 显示对再灌注损伤的保护作用。
T3102 NS-1619

Apoptosis; Potassium Channel Apoptosis; Membrane transporter/Ion channel
NS 1619 是 Ca2+激活的 K+(BK) 通道的激活剂,是一种高效的松弛剂,在血管和其他组织的几个平滑肌中的 EC50约为 10 – 30 μM。它抑制A2780卵巢癌细胞增殖并诱导细胞凋亡。
T4510 Polaprezinc

Zinc L-carnosine,聚普瑞锌,L-肌肽锌

Others Others
Polaprezinc是一种含有锌和L-carnosine的生物可用螯合物,以其胃肠保护性能、抗溃疡、抗氧化和抗炎效果而闻名。
T14061 EMCS

6-Maleimidohexanoic acid N-hydroxysuccinimide ester

Others; ADC Linker Antibody-drug Conjugate/ADC Related; Others
EMCS (6-Maleimidohexanoic acid N-hydroxysuccinimide ester) 是一种异双官能团交联剂,是一种制备半抗原结合物和酶免疫偶联物的化合物,是抗体药物偶联物中一种有效的保护基团。
T72059 S1R agonist 2

Sigma receptor; ROS; NMDAR GPCR/G Protein; Immunology/Inflammation; Neuroscience
S1R agonist 2 是一种具有选择性的 S1R 激动剂,对 S2R 和 S1R 的 Ki 分别为88 nM 和 1.1 nM, 对 ROS 和 NMDA 诱导的神经毒性具有保护作用。
T21470L Davunetide acetate

Davunetide acetate(211439-12-2 Free base)

Beta Amyloid; Microtubule Associated Cytoskeletal Signaling; Neuroscience
Davunetide acetate 源自哺乳动物 CNS 中存在的活性依赖性神经保护蛋白。 Davunetide acetate 是一种微管稳定肽,可抑制 Aβ 聚集和 Aβ 诱导的神经毒性。 Davunetide acetate 具有神经保护、神经营养和认知保护特性。
T5672 2,4-Diaminophenoxyethanol HCl

Others Others
2,4-Diaminophenoxyethanol HCl 是一种单萜,以及结构相关的 1,8-桉树脑和樟脑,已显示出对癌症的保护作用,对多种微生物的生物活性,和抗氧化特性。
T32105 Cipepofol

HSK3486,HSK-3486,CS-0064163,HSK 3486

Apoptosis; GABA Receptor Apoptosis; Membrane transporter/Ion channel; Neuroscience
Cipepofol (HSK3486) 是一种 GABAA 受体激动剂,具有镇静作用,在多种心血管疾病中起保护作用。Cipepofol 可激活 Sirtuin1 (Sirt1)/Nrf2 通路,可诱导心肌细胞凋亡,可用于研究心肌梗塞、心肌缺血再灌注损伤和章鱼壶综合征。
T67717L Questiomycin A derivatives 18 TFA

Others Others
Questiomycin A derivatives 18 TFA 是一种Questiomycin A 衍生物,Questiomycin A 具有抗菌和抗癌活性 ,对细胞保护性 ER 伴侣蛋白 GRP78 的表达具有抑制作用。
T9180 LUF6096

CF-602

Adenosine Receptor GPCR/G Protein; Neuroscience
LUF6096 (CF-602) 是一种有效的腺苷 A3 受体 (adenosine A3 receptor) 变构增强剂。LUF6096 对任何腺苷受体显示出低正构亲和力。LUF6096 在心肌缺血/再灌注损伤中显示出保护作用。
T28248 Ono-3307 mesylate

Ono-3307,Ono3307,Ono 3307

Protease Proteases/Proteasome
Ono-3307 mesylate 是一种蛋白酶抑制剂,对多种蛋白酶均具有抑制作用。Ono-3307 mesylate 对大鼠的肝损伤具有显着的保护作用,抑制放射性纤维蛋白在肾脏和肺部的沉积 ,可用于研究胰腺炎。
T16724 Razuprotafib

AKB-9778

Phosphatase; Others Metabolism; Others
Razuprotafib (AKB-9778) 是一种 VE-PTP (HPTPß)催化活性的有效选择性抑制剂,抑制结构相关磷酸酶 PTP1B。除 HPTPη 和 HPTPγ 外,它对 VE-PTP 具有良好的选择性。它能够促进 TIE2 活化,增强 ANG1 诱导的 TIE2 活化,并刺激 TIE2 通路中信号分子的磷酸化。
T77245 Mannan

Endogenous Metabolite Metabolism
Mannan 是从藻类、蘑菇、酵母和高等植物中分离出的,可作为免疫调节剂。Mannan 抑制肝脏巨噬细胞(M1谱系)的促炎活性对许多肝脏病变(例如坏死或脂肪变性)具有保护作用。
T22905 L748337

L-748,337

Adrenergic Receptor GPCR/G Protein; Neuroscience
L748337是一种具有竞争性和高效性的 β3-肾上腺素受体拮抗剂,抑制 β3-、β2- 和 β1-肾上腺素受体发挥作用,激活 MAPK 信号传导,促进 Erk1/2 的磷酸化,抑制CL316243 的保护作用,可用于研究和β3-肾上腺素受体异常引起的疾病。
T13416 ZX-29

ALK Angiogenesis; Tyrosine Kinase/Adaptors
ZX-29 是一种选择性ALK 抑制剂,对ALK、ALK L1196M 和ALK G1202R 的IC50分别为 2.1 nM、1.3 nM 和 3.9 nM。它还可诱导保护性自噬并具有抗肿瘤作用。它通过诱导内质网应激来诱导细胞凋亡,并克服了由ALK 突变引起的细胞抗性。
T67908 ThioLox

Lipoxygenase Metabolism
ThioLox 是一种竞争性 15-脂氧合酶-1 (15-LOX-1) 抑制剂(IC50值为12 μM)。ThioLox 显示抗炎和神经保护特性。具有抗炎和神经保护作用,对谷氨酸毒性有很强的保护作用。
T36619 Aligeron

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Aligeron 是一种非选择性的prostaglandin (PG)拮抗剂,对PGF2α和PGE2诱导的猫血压下降有抑制作用,可用于抑制PGF2α诱导的小鼠腹泻和PGE2诱导的大鼠爪水肿。Aligeron 对血管并发症具有抗氧化保护作用。
T13396 Zinc Protoporphyrin

Zinc Protoporphyrin-9,锌原卟啉,ZnPP,Zn(II)-protoporphyrin IX

Apoptosis; Reactive Oxygen Species; Endogenous Metabolite Apoptosis; Immunology/Inflammation; Metabolism; NF-κB
Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) 是一种具有口服活性的,竞争性血红素加氧酶-1 抑制剂,显著减弱间苯三酚对 H2O2 的保护作用,具有抗癌活性。它用于评估人群铁状态与血红蛋白浓度的组合,也可用作个体孕妇和儿童缺铁的筛查标志物。
T20681 Estramustine

NSC-89201,NSC 89201,LEO 275,LEO275,雌莫司汀,NSC89201,LEO-275

Microtubule Associated Cytoskeletal Signaling
Estramustine (LEO-275) 是一种与雌二醇相连的氮芥,通常为磷酸盐。它已被用于治疗前列腺肿瘤;还具有防辐射功能。它被前列腺细胞选择性吸收,并通过干扰微管动力学和降低血浆睾酮水平发挥抗肿瘤作用。
T37436 C12-Ceramide

N-Laurylsphingosine,C12 Ceramide (d18:1/12:0),N-Lauroyl-D-erythro-sphingosine

C12-Ceramide (C12 Ceramide (d18:1/12:0)) 是一种存在于先兆子痫妇女所生婴儿围绕脐带血管的保护膜的神经酰胺,是 C12 鞘磷脂被酸性鞘磷脂酶(ASM)水解后形成的,可用于评估 A 型或 B 型尼曼-皮克病患者血浆中的 ASM 活性水平。
T16031 McMMAF

Maleimidocaproyl monomethylauristatin F

Microtubule Associated; Drug-Linker Conjugates for ADC Antibody-drug Conjugate/ADC Related; Cytoskeletal Signaling
McMMAF 是一种保护基团共轭的 MMAF。它是一种具有马来酰亚胺基己酰基接头(MC 接头)的 MMAF 衍生物, MMAF 是一种有效的微管蛋白聚合抑制剂。它可与抗体或其他蛋白质或生物聚合物结合。
T7072 Pitavastatin

Others Others
Pitavastatin (NK-104) 是有效的羟甲基戊二酰-CoA(HMG-CoA)还原酶抑制剂。Pitavastatin 抑制乙酸合成胆固醇,在 HepG2 细胞中的IC50为 5.8 nM。Pitavastatin 是一种高效的肝细胞低密度脂蛋白胆固醇 (LDL-C) 受体诱导剂。Pitavastatin 具有抗动脉粥样硬化、抗哮喘、抗骨关节炎、抗肿瘤、神经保护、肝保护和肾保护等作用。
T50032 5-(2-furyl)-N-propylisoxazole-3-carboxamide

Others Others
5-(2-furyl)-N-propylisoxazole-3-carboxamide 是一种用作分子结构单元的化合物,被认为是 NMDA 受体的调节剂,已被证明对神经元细胞中谷氨酸诱导的兴奋性毒性和氧化应激具有保护作用。它也被发现具有抗炎活性,使其成为阿尔茨海默病和帕金森病等疾病的潜在治疗剂。
T11518L GW274150

NOS Immunology/Inflammation
GW274150 是一种具有口服活性,选择性和高效性的 NADPH 依赖型人一氧化氮合成酶 (iNOS) (Kd=40 nM) 和大鼠诱导型一氧化氮合酶 (iNOS) 双重抑制剂。GW274150 对人和大鼠的内皮一氧化氮合酶 (eNOS) 和神经元一氧化氮合酶 (nNOS) 活性较低。在急性肺损伤炎症模型中,GW274150 表现出保护作用。
T1880 P7C3

Others Others
P7C3 是一种 aminopropyl carbazole 类化合物,具有口服活性,可透过血脑屏障,具有神经保护作用。它可用于神经退行性疾病,如帕金森病的研究。
T21967 MEG hemisulfate

Mercaptoethylguanidine hemisulfate

NOS Immunology/Inflammation
MEG hemisulfate (Mercaptoethylguanidine hemisulfate) 是一种有效和选择性的诱导型 NO 合酶 (iNOS) 的抑制剂,在组织匀浆中抑制 iNOS,ecNOS 和 bNOS 的 EC50 值分别为 11.5,110 和 60 μM。MEG hemisulfate 也有效的过氧亚硝酸盐清除剂,可抑制过氧亚硝酸盐诱导的氧化过程。MEG hemisulfate 在许多炎症实验模型中具有保护作用,包括缺血/再灌注损伤,牙周炎,失血性休克,炎性肠病以及内毒素和败血性休克。
T9948 NecroX-7

LC-280126,LC28-0126,LC28 0126

NADPH-oxidase Immunology/Inflammation
NecroX-7 (LC-280126) 是一种有效的自由基清除剂和 HMGB1(高迁移率族蛋白 1) 抑制剂。NecroX-7 可以作为对乙酰氨基酚毒性的解毒剂。NecroX-7 通过抑制缺血/再灌注损伤中 HMGB1 的释放发挥保护作用。NecroX-7 抑制 HMGB1 诱导的 TNF 和 IL-6的释放,以及TLR-4和晚期糖基化终产物受体的表达,用于移植物抗宿主病 (GVHD) 研究。
T23709 alphaSYN-IN-NAB2

alphaSYN inhibitor NAB2,alphaSYNINNAB2,alphaSYN-IN-NAB2,NAB2,alphaSYN inhibitor-NAB2

Others Others
alphaSYN-IN-NAB2 是一种神经元保护剂,是一种由 NAB2基因编码的蛋白质。NAB2 高效且具有选择性地保护多种细胞免受 α-syn 毒性。NAB2 对依赖于 E3 泛素连接酶 Rsp5/Nedd4 的内体转运具有促进作用。NAB2 确定 α-syn 生物学中的一个可活性分子节点,该节点可以纠正其潜在病理学的多个方面,包括功能失调的内体和内质网到高尔基体囊泡的运输。NAB2参与细胞分化、凋亡和应激反应等细胞过程,可用来研究癌症、神经发育和神经元活动。

化合物

Pyrintegrin
Cat.No: T16695
Synonym:
Target: Integrin
Lercanidipine
Cat.No: T2519
Synonym: 乐卡地平,Masnidipine
Target: Calcium Channel
Zacopride hydrochloride
Cat.No: T5336
Synonym:
Target: Potassium Channel, 5-HT Receptor
Idebenone
Cat.No: T0412
Synonym: 艾地苯醌,CV-2619
Target: Apoptosis, Antioxidant, Mitochondrial Metabolism
Lafutidine
Cat.No: T0081
Synonym: 拉呋替丁,FRG-8813
Target: 5-HT Receptor, Histamine Receptor
RWJ-67657
Cat.No: T16812
Synonym: JNJ 3026582
Target: p38 MAPK
Lercanidipine hydrochloride
Cat.No: T6874
Synonym: Corifeo,Carmen,Cardiovasc,乐卡地平盐酸盐,盐酸乐卡地平
Target: Calcium Channel
Alfacalcidol
Cat.No: T6374
Synonym: Bondiol,Etalpha,阿法骨化醇,1-hydroxy Vitamin D3,1.alpha.-Hydroxyvitamin D3,1-hydroxycholecalciferol
Target: Others
Neuroprotective agent 1
Cat.No: T50107
Synonym:
Target: Others
Cardioxane
Cat.No: T6467
Synonym: ADR-529 Hydrochloride,ICRF-187 hydrochloride,ADR-529,右雷佐生盐酸盐,Dexrazoxane HCl,Cardioxane hydrochloride,ICRF-187
Target: Topoisomerase
STS-E412
Cat.No: T24840
Synonym: STS E412,STSE412
Target: Others
DHMB
Cat.No: T21252
Synonym: 2,3-Dihydroxy-4-Methoxybenzaldehyde
Target: Others
Spizofurone
Cat.No: T24821
Synonym: Espizofurona,AG-629
Target: Others
Chromocarb
Cat.No: T0259
Synonym: Chromone-2-carboxylic acid,色烯卡,Chromocarbe
Target: Others
Cystamine dihydrochloride
Cat.No: T20109
Synonym:
Target: Others
Esaprazole
Cat.No: T31675
Synonym: C/63
Target: Others
Sabeluzole
Cat.No: T28655
Synonym: R 58735,R58735,R-58735
Target: Microtubule Associated
KX1-004
Cat.No: T1812
Synonym: KX1 004,KX1004
Target: Src
AR420626
Cat.No: T26647
Synonym: AR 420626,AR-420626
Target: Others
Aplodan
Cat.No: T20843
Synonym: Nergize,Creatinolfosfate,磷酸肌肉醇,creatinol-O-phosphate,Creatinolfosfate, Creatinol Phosphate
Target: Others
Prolyl-4-hydroxylase Inhibitor 11
Cat.No: T65816
Synonym:
Target: Others
RH01687
Cat.No: T8982
Synonym:
Target: Others
Daltroban
Cat.No: T15049
Synonym: BM-13505,SKF 96148
Target: PPAR
NS-1619
Cat.No: T3102
Synonym:
Target: Apoptosis, Potassium Channel
Polaprezinc
Cat.No: T4510
Synonym: Zinc L-carnosine,聚普瑞锌,L-肌肽锌
Target: Others
EMCS
Cat.No: T14061
Synonym: 6-Maleimidohexanoic acid N-hydroxysuccinimide ester
Target: Others, ADC Linker
S1R agonist 2
Cat.No: T72059
Synonym:
Target: Sigma receptor, ROS, NMDAR
Davunetide acetate
Cat.No: T21470L
Synonym: Davunetide acetate(211439-12-2 Free base)
Target: Beta Amyloid, Microtubule Associated
2,4-Diaminophenoxyethanol HCl
Cat.No: T5672
Synonym:
Target: Others
Cipepofol
Cat.No: T32105
Synonym: HSK3486,HSK-3486,CS-0064163,HSK 3486
Target: Apoptosis, GABA Receptor
Questiomycin A derivatives 18 TFA
Cat.No: T67717L
Synonym:
Target: Others
LUF6096
Cat.No: T9180
Synonym: CF-602
Target: Adenosine Receptor
Ono-3307 mesylate
Cat.No: T28248
Synonym: Ono-3307,Ono3307,Ono 3307
Target: Protease
Razuprotafib
Cat.No: T16724
Synonym: AKB-9778
Target: Phosphatase, Others
Mannan
Cat.No: T77245
Synonym:
Target: Endogenous Metabolite
L748337
Cat.No: T22905
Synonym: L-748,337
Target: Adrenergic Receptor
ZX-29
Cat.No: T13416
Synonym:
Target: ALK
ThioLox
Cat.No: T67908
Synonym:
Target: Lipoxygenase
Aligeron
Cat.No: T36619
Synonym:
Target: Prostaglandin Receptor
Zinc Protoporphyrin
Cat.No: T13396
Synonym: Zinc Protoporphyrin-9,锌原卟啉,ZnPP,Zn(II)-protoporphyrin IX
Target: Apoptosis, Reactive Oxygen Species, Endogenous Metabolite
Estramustine
Cat.No: T20681
Synonym: NSC-89201,NSC 89201,LEO 275,LEO275,雌莫司汀,NSC89201,LEO-275
Target: Microtubule Associated
C12-Ceramide
Cat.No: T37436
Synonym: N-Laurylsphingosine,C12 Ceramide (d18:1/12:0),N-Lauroyl-D-erythro-sphingosine
Target:
McMMAF
Cat.No: T16031
Synonym: Maleimidocaproyl monomethylauristatin F
Target: Microtubule Associated, Drug-Linker Conjugates for ADC
Pitavastatin
Cat.No: T7072
Synonym:
Target: Others
5-(2-furyl)-N-propylisoxazole-3-carboxamide
Cat.No: T50032
Synonym:
Target: Others
GW274150
Cat.No: T11518L
Synonym:
Target: NOS
P7C3
Cat.No: T1880
Synonym:
Target: Others
MEG hemisulfate
Cat.No: T21967
Synonym: Mercaptoethylguanidine hemisulfate
Target: NOS
NecroX-7
Cat.No: T9948
Synonym: LC-280126,LC28-0126,LC28 0126
Target: NADPH-oxidase
alphaSYN-IN-NAB2
Cat.No: T23709
Synonym: alphaSYN inhibitor NAB2,alphaSYNINNAB2,alphaSYN-IN-NAB2,NAB2,alphaSYN inhibitor-NAB2
Target: Others
Cat. No. Product Name Target Signaling Pathways
T8158 Tilianin

香清兰苷,田蓟苷

Others Others
Tilianin 是一种广泛存在于多种药用植物中的活性黄酮类苷,具有降压、保护心肌、降血脂、抗糖尿病、抗炎、抗氧化等作用。
T2808 Bilobalide

白果内酯,银杏内酯,(-)-Bilobalide

Apoptosis; Endogenous Metabolite; Autophagy Apoptosis; Autophagy; Metabolism
Bilobalide ((-)-Bilobalide) 是银杏叶中的的一种倍半萜三内酯成分,抑制 NMDA 诱导的胆碱流出,IC50值为 2.3 µM。它通过激活 SH-SY5Y 细胞中的 PI3K/Akt 通路来防止细胞凋亡。对神经元发挥保护和营养作用。
T2S1200 Sinapine

Antioxidant; P-gp; AChE Membrane transporter/Ion channel; Neuroscience; oxidation-reduction
Sinapine 是萝卜中分离出来的一种生物碱,具有抗炎、抗氧化、抗肿瘤、抗血管生成和放射防护作用。它还是乙酰胆碱酯酶抑制剂,可用于研究阿尔茨海默症,共济失调,重症肌无力和帕金森氏病。
TN6774 Emodin 6-O-β-D-glucoside

大黄素-6-O-β-D-葡萄糖苷,Glucoemodin

Others Others
Emodin 6-O-β-D-glucoside (Glucoemodin) 是一种从 Reynoutria japonica 中提取的活性化合物。它具有显著的抗炎和屏障保护活性,可用于研究动脉粥样硬化及糖尿病并发症。
T6S1525 3,4-Dicaffeoylquinic acid

Isochlorogenic acid B,金银花,异绿原酸B

Apoptosis; Antioxidant; Influenza Virus; Endogenous Metabolite Apoptosis; Metabolism; Microbiology/Virology; oxidation-reduction
3,4-Dicaffeoylquinic acid (Isochlorogenic acid B) 是一种天然产物,具有α-葡萄糖苷酶抑制作用和凋亡介导的细胞毒性 。它还具有抗病毒、抗氧化、DNA 保护、神经保护和肝保护特性。
T3392 Sinapine thiocyanate

P-gp; AChE Membrane transporter/Ion channel; Neuroscience
Sinapine thiocyanate 是萝卜中分离出来的一种生物碱,具有抗炎、抗氧化、抗肿瘤、抗血管生成和放射防护作用。它还是乙酰胆碱酯酶抑制剂,可用于研究阿尔茨海默症,共济失调,重症肌无力和帕金森氏病。
T5145 Oxytocin acetate

Oxytocic hormone acetate,α-Hypophamine acetate,Oxytocin acetate (50-56-6 free base),醋酸催产素

Oxytocin Receptor Endocrinology/Hormones; GPCR/G Protein
Oxytocin acetate (α-Hypophamine acetate) 是哺乳动物的神经垂体激素,是多效的下丘脑肽,是催产素受体的配体,有助于分娩、哺乳和亲社会行为。它可作为一种压力应对分子,具有抗炎、抗氧化剂和保护作用。
T6S1917 Schisandrol B

Gomisin A,TJN-101,Besigomsin,五味子醇乙,Gamma-Schisandrin,戈米辛A,Schizandrol B,Wuweizi alcohol-B

P450; Reactive Oxygen Species; Autophagy Autophagy; Immunology/Inflammation; Metabolism; NF-κB
Schisandrol B (Besigomsin) 是华中五味子的主要活性成分,具有保肝、抗炎、抗糖尿病和抗氧化的作用。它抑制活性氧的产生,也抑制 P-糖蛋白和CYP3A 的活性。
T80778 weak Hepatoprotective agent-1

Weak Hepatoprotective agent-1 (Compound 11),一种从Arctium lappa L. 分离得到的天然产物,在10 μM浓度下具有弱肝保护活性。
T3S1534 Secoxyloganin

断氧化马钱苷,幼枝含断氧化马钱子甙,金银花

Anti-infection Microbiology/Virology
Secoxyloganin 是从Lonicera japonicaThunb 提取得到,能够抑制血流量减少,具有抗过敏活性。
TN4973 Sculponeatin O

Others Others
Sculponeatin O 是一种 ent-kaurane 二萜衍生物,分离自 Isodon sculponeata 植物。
T5760 (-​)​-​Salutaridine

清风藤碱,SINOACUTINE

Others Others
(-​)​-​Salutaridine 是一种生物碱。
T3S0289 Araloside X

Calcium Channel Membrane transporter/Ion channel; Metabolism
Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the amelioration of FFA metabolic deterioration and membrane peroxidation induced by oxygen free radi
T6S1367 Procyanidin B2

原花青素 B2,Proanthocyanidin B2

Reactive Oxygen Species; NOD Immunology/Inflammation; Metabolism; NF-κB
Procyanidin B2 (Proanthocyanidin B2) 是天然黄酮类物质,具有抗肿瘤,抗氧化等活性。
T5S1632 Barlerin

8-O-乙酰山栀苷甲酯,8-O-Acetylshanzhiside methyl ester,ND01

VEGFR; TNF; NF-κB; Akt; Caspase Angiogenesis; Apoptosis; Cytoskeletal Signaling; NF-κB; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Tyrosine Kinase/Adaptors
Barlerin (8-O-Acetylshanzhiside methyl ester) 是一种环孢菌素葡萄糖苷,从中国西藏民间药用植物中分离得到,能够抑制NF-κB 活性。
TN1494 Cimicifugoside H-1

黑升麻苷H-1

Others Others
Cimicifugoside H1 是C. foetidaL.C 提取物的主要成分,是一种环甾烷醇木糖苷。它对骨吸收及卵巢切除术引起的骨质流失具有抑制作用。
T6S2246 Alisol B 23-acetate

Alisol B Acetate,Alisol B monoacetate,23-O-Acetylalisol B,23-Acetylalismol B,泽泻醇B乙酸酯

Others Others
Alisol B 23-acetate (Alisol B Acetate) 是三萜类化合物,能够激活法尼醇受体,诱导受损的肝脏再生。
T5665 Geraniol

Others; Endogenous Metabolite; Antifungal Metabolism; Microbiology/Virology; Others
Geraniol 对糖尿病引起的心脏功能障碍起保护作用,抑制氧化应激。
TN1058 Pelargonidin chloride

NOS; Reactive Oxygen Species; Nrf2; NO Synthase Immunology/Inflammation; Metabolism; NF-κB
Pelargonidin chloride 是一种氧化氮自由基的清除剂,具有抗氧化作用。
TN1274 4-Allylcatechol

2-羟基胡椒酚,4-Allylpyrocatechol,Hydroxychavicol

Others Others
4-Allylcatechol (Hydroxychavicol) 是合成黄樟素的一种中间体。
T8200 Ginkgolide K

银杏内酯 K,银杏内酯K

AMPK; Autophagy Autophagy; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
Ginkgolide K 是从银杏中分离得到的一种二萜类天然产物,有神经保护活性,可通过 AMPK/mTOR/ULK1信号通路诱导保护性自噬。
T4S0217 HOMOPLANTAGININ

TNF; NF-κB Apoptosis; NF-κB
Homoplantaginin 是来自中药荔枝草的一种类黄酮,具有抗炎和抗氧化活性。
TN1650 Friedelin

软木三萜酮,无羁萜

P450; NOS; Caspase; Prostaglandin Receptor Apoptosis; GPCR/G Protein; Immunology/Inflammation; Metabolism; Proteases/Proteasome
Friedelin 是分离自 Maytenus ilicifolia(Mart) 的叶子。它是 CYP3A4的非竞争性抑制剂,其 IC50和 Ki 分别为10.79 μM 和 6.16 μM,也是 CYP2E1的竞争性抑制剂,其 IC50和 Ki 分别为 22.54 μM 和 18.02 μM。
TN4661 Nodosin

IL Receptor; Autophagy Autophagy; Immunology/Inflammation
Nodosin 是一种二萜化合物,从Isodon trichocarpusKudo 和I. JaponicusHARA 中提取得到。
T4S1983 Periplogenin

5-beta-Hydroxydigitoxigenin,Desoxostrophanthidin,杠柳苷元

Others Others
Periplogenin (Desoxostrophanthidin) 是一种天然呋喃香豆素,存在于白芷根中,可以诱导脂肪细胞分化,具有高抗银屑病作用。
T4829 3-Hydroxyphenylacetic acid

Others; Endogenous Metabolite Metabolism; Others
3-Hydroxyphenylacetic acid 是内源性代谢产物的一种。
T1391 4-Methylumbelliferone

Hymecromone,4-MU,胆通

Others Others
4-Methylumbelliferone (Hymecromone) 是透明质酸生物合成抑制剂,显示出抗肿瘤和抗转移活性。
T6S1294 Nicotiflorin

Nictoflorin,Kaempferol-3-O-Rutinoside,山奈酚-3-O-芸香糖苷,Nicotifloroside

Others Others
Nicotiflorin (Kaempferol-3-O-Rutinoside) 是一种黄酮苷,从传统中药Flos Carthami 中提取得到。它有抗糖化活性和神经保护作用。
T5S0045 Isofraxidin

6,8-Dimethoxyumbelliferone,异秦皮啶,Phytodolor,异嗪皮啶

MMP; ERK; p38 MAPK; TLR; COX Immunology/Inflammation; MAPK; Neuroscience; Proteases/Proteasome
Isofraxidin (Phytodolor) 是来自刺五加的香豆素成分,抑制MMP-7表达和人肝癌细胞侵袭。它作用于肝癌细胞,抑制ERK1/2磷酸化。它减弱iNOS 和COX-2表达,还抑制TLR4/髓样分化蛋白 2 复合物的形成。
T3405 [6]-Gingerol

6-Gingerol,gingerol,(S)-(+)-[6]Gingerol,6-姜酚

Apoptosis; AMPK Apoptosis; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
[6]-Gingerol ((S)-(+)-[6]Gingerol) 是一种从生姜中分离的活性物质,具有抗癌,抗炎和抗氧化活性。
T36818 Questiomycin A

GPR; Antibacterial Endocrinology/Hormones; GPCR/G Protein; Microbiology/Virology
Questiomycin A 是一种在鲜奶油中生产的抗生素,具有抗菌和抗癌活性。 Questiomycin A 抑制细胞保护性 ER 伴侣蛋白 GRP78 的表达。
TN7134 Magnoloside B

Glucosidase Metabolism
Magnoloside B 是一种来自木兰果实的苯乙醇糖苷,是一种 α-glucosidase 抑制剂,对自由基诱导的氧化损伤的保护作用,可用于研究癌症。
T19792 1,3,7-Trimethyluric acid

Others Others
1,3,7-Trimethyluric acid 是咖啡因的代谢产物。其与咖啡因的代谢比可以反映 CYP3A 活性的变化情况。
TN1238 3,4-O-Isopropylidene-shikimic acid

3,4-O-异亚丙基莽草酸,3,4-O-Isopropylidene shikimic acid

NOS; NO Synthase Immunology/Inflammation
3,4-O-Isopropylidene-shikimic acid (3,4-O-Isopropylidene shikimic acid) 是一种从Hypericum wightianum 中提取得到的天然产物。它具有抗炎症和抗氧化作用。
T5751 Tigogenin

Others Others
Tigogenin 是甾体皂甙元,普遍用于甾体类药物的合成。它能够阻碍小鼠骨髓基质细胞脂肪细胞分化,促使成骨细胞的分化。
T2S0500 Ilexsaponin A

毛冬青皂苷A,毛冬青皂苷甲,Ilexsaponin A1

Others Others
Ilexsaponin A (Ilexsaponin A1)1 是分离自冬凌草的根中,利用抗凋亡途径减轻缺血再灌注引起的心肌损伤。它能够减少心肌梗塞的大小,减少 LDH,AST 和 CK-MB 的血清水平,促进细胞活力并抑制缺氧/复氧心肌细胞的凋亡。
T4454 Traumatic Acid

Dodec-2-Enedioic Acid,2E-Dodecenedioic Acid,愈伤酸,Trans-2-Dodecenedioic Acid

Antioxidant oxidation-reduction
Traumatic Acid (Dodec-2-Enedioic Acid) 是一种单不饱和二元羧酸,从菜豆中分离得到。它可减少膜磷脂的过氧化,并表现出抗氧化和对胶原生物合成的刺激作用。它可用于许多与胶原蛋白生物合成障碍和氧化应激有关的皮肤疾病的研究。
T19866 Indican

NSC-87517,3-Indoxyl-beta-D-glucopyranoside,3-吲哚基-beta-D-吡喃葡萄糖苷,NSC 87517,NSC87517,Indoxyl-β-D-glucoside

OAT; MRP Immunology/Inflammation; Membrane transporter/Ion channel
Indican (Indoxyl-β-D-glucoside) 是吲哚酚的一种糖苷,染料靛蓝和靛玉红的前体。它的主要代谢物是硫酸吲哚酚 (IS)。其中 IS 是尿毒症毒素,是有机阴离子转运蛋白1 (OAT 1)、OAT 3 和多药耐药相关蛋白4 (MRP 4) 的底物/抑制剂。
TMS2180 Zeaxanthin

Anchovyxanthin,All-Trans-Zeaxanthin,玉米

Antioxidant; Endogenous Metabolite Metabolism; oxidation-reduction
Zeaxanthin (All-Trans-Zeaxanthin) 是食物获得类胡萝卜素,存在于眼睛的黄斑部,具有抗氧化活性。
T25253 Cinnamtannin B-1

Cinnamtannin B1 (constituent of cinnamomum verum bark),LDN 0022358,LDN-0022358,LDN0022358,肉桂单宁B-1

Antioxidant; COX Immunology/Inflammation; Neuroscience; oxidation-reduction
Cinnamtannin B-1 (LDN 0022358) 是一种 A 型原花青素,包含在多种植物中,如越桔、桂树、泽兰肉桂和猪苓。它是一种有效的抗氧化剂和保护剂,可对抗人类血小板的氧化应激和凋亡。它是一种 Cox-2抑制剂。
T4953 Neotuberostemonine

NOS Immunology/Inflammation
Neotuberostemonine 是一种结核分枝杆菌根中主要的止咳生物碱,能够阻碍巨噬细胞的募集和活化,从而减轻博来霉素 (Bleomycin) 诱导的肺纤维化。
T5S0285 Cistanoside A

肉苁蓉苷 A,肉苁蓉苷A

Others Others
Cistanoside A 是一种肉苁蓉中的苯丙素类化合物,能够抑制 NO 的聚集,但不影响诱导型一氧化氮合酶 iNOS 的 mRNA 和蛋白水平及其活性。它具有抗炎作用。
TN2173 Salvianolic acid D

(R,E)-2-((3-(2-(carboxymethyl)-3,4-dihydroxyphenyl)acryloyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid,丹酚酸D,丹酚酸 D

Others Others
Salvianolic acid D ((R,E)-2-((3-(2-(carboxymethyl)-3,4-dihydroxyphenyl)acryloyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid) 是一种分离自Salvia miltiorrhiza 中的化合物,有潜在抗血小板作用。
T2S0690 Ecliptasaponin A

早莲苷 A,旱莲苷A,Echinocystic acid-3-o-glucoside

Others Others
Ecliptasaponin A (Echinocystic acid-3-o-glucoside) 是一种墨旱莲 (Eclipta prostrate) 中分离得到的五环三萜皂苷。其中墨旱莲是一种具有多效作用的滋补草药,如抗炎、保肝、抗氧化和免疫调节。
TWS1563 Incensole

Others Others
Incensole 是一种 14-membered 二萜类化合物,分离自烯属植物的香精油和乳香树脂中。它能够激活脑中离子通道,并可以缓解焦虑或抑郁,从而显示出抗炎和抗抑郁的特性。
T5S1285 (+)-(3R,8S)-Falcarindiol

Falcarindiol,镰叶芹二醇

Others Others
(+)-(3R,8S)-Falcarindiol 是一种从胡萝卜中得到的聚乙炔,有抗炎、抗肿瘤和抗脂质过氧化活性。它具有抗分歧杆菌作用,对Mycobacterium tuberculosisH37Ra 的 MIC 和 IC50值分别为 24 μM 和 6 μM。
T15705 Laminaran

β-1,3-Glucan

Laminaran 是一种从褐藻中分离出来的 β-1-3-葡聚糖,常作为 Dectin-1 的典型配体,具有抗癌、免疫调节和辐射防护作用。 Laminaran 可被葡糖酶催化。Laminaran 在体内外实验中显示出抗肿瘤活性,可用于预防和治疗癌症。
T3920 Pseudoginsenoside F11

Ginsenoside A1,拟人参皂苷 F11,拟人参皂苷F11

Others; Endogenous Metabolite Metabolism; Others
Pseudoginsenoside F11 (Ginsenoside A1) 从人参根和叶中分离得到。PF11在一系列心血管和中枢神经系统疾病中具有广泛的保护作用。
TN1921 Meloside A

异牡荆素-2''-O-葡萄糖苷,Isovitexin 2''-O-glucoside,Isovitexin 2''-O-β-D-glucoside

Others Others
Meloside A (Isovitexin 2''-O-β-D-glucoside) 是一种从大麦中提取的苯丙烷类天然产物。 Meloside A 对过量的 UV-B 辐射具有抗氧化和保护作用,并与对病原体的抵抗力有关。
TN1722 Hamamelitannin

Antifection Microbiology/Virology
Hamamelitannin 是分离自 Hamamelis virginiana 树皮的一种多酚,是群体感应抑制剂。它通过影响肽聚糖生物合成和 eDNA 释放增加金黄色葡萄球菌生物膜的抗生素敏感性。
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天然产物

Tilianin
Cat.No: T8158
Synonym: 香清兰苷,田蓟苷
Target: Others
Bilobalide
Cat.No: T2808
Synonym: 白果内酯,银杏内酯,(-)-Bilobalide
Target: Apoptosis, Endogenous Metabolite, Autophagy
Sinapine
Cat.No: T2S1200
Synonym:
Target: Antioxidant, P-gp, AChE
Emodin 6-O-β-D-glucoside
Cat.No: TN6774
Synonym: 大黄素-6-O-β-D-葡萄糖苷,Glucoemodin
Target: Others
3,4-Dicaffeoylquinic acid
Cat.No: T6S1525
Synonym: Isochlorogenic acid B,金银花,异绿原酸B
Target: Apoptosis, Antioxidant, Influenza Virus, Endogenous Metabolite
Sinapine thiocyanate
Cat.No: T3392
Synonym:
Target: P-gp, AChE
Oxytocin acetate
Cat.No: T5145
Synonym: Oxytocic hormone acetate,α-Hypophamine acetate,Oxytocin acetate (50-56-6 free base),醋酸催产素
Target: Oxytocin Receptor
Schisandrol B
Cat.No: T6S1917
Synonym: Gomisin A,TJN-101,Besigomsin,五味子醇乙,Gamma-Schisandrin,戈米辛A,Schizandrol B,Wuweizi alcohol-B
Target: P450, Reactive Oxygen Species, Autophagy
weak Hepatoprotective agent-1
Cat.No: T80778
Synonym:
Target:
Secoxyloganin
Cat.No: T3S1534
Synonym: 断氧化马钱苷,幼枝含断氧化马钱子甙,金银花
Target: Anti-infection
Sculponeatin O
Cat.No: TN4973
Synonym:
Target: Others
(-​)​-​Salutaridine
Cat.No: T5760
Synonym: 清风藤碱,SINOACUTINE
Target: Others
Araloside X
Cat.No: T3S0289
Synonym:
Target: Calcium Channel
Procyanidin B2
Cat.No: T6S1367
Synonym: 原花青素 B2,Proanthocyanidin B2
Target: Reactive Oxygen Species, NOD
Barlerin
Cat.No: T5S1632
Synonym: 8-O-乙酰山栀苷甲酯,8-O-Acetylshanzhiside methyl ester,ND01
Target: VEGFR, TNF, NF-κB, Akt, Caspase
Cimicifugoside H-1
Cat.No: TN1494
Synonym: 黑升麻苷H-1
Target: Others
Alisol B 23-acetate
Cat.No: T6S2246
Synonym: Alisol B Acetate,Alisol B monoacetate,23-O-Acetylalisol B,23-Acetylalismol B,泽泻醇B乙酸酯
Target: Others
Geraniol
Cat.No: T5665
Synonym:
Target: Others, Endogenous Metabolite, Antifungal
Pelargonidin chloride
Cat.No: TN1058
Synonym:
Target: NOS, Reactive Oxygen Species, Nrf2, NO Synthase
4-Allylcatechol
Cat.No: TN1274
Synonym: 2-羟基胡椒酚,4-Allylpyrocatechol,Hydroxychavicol
Target: Others
Ginkgolide K
Cat.No: T8200
Synonym: 银杏内酯 K,银杏内酯K
Target: AMPK, Autophagy
HOMOPLANTAGININ
Cat.No: T4S0217
Synonym:
Target: TNF, NF-κB
Friedelin
Cat.No: TN1650
Synonym: 软木三萜酮,无羁萜
Target: P450, NOS, Caspase, Prostaglandin Receptor
Nodosin
Cat.No: TN4661
Synonym:
Target: IL Receptor, Autophagy
Periplogenin
Cat.No: T4S1983
Synonym: 5-beta-Hydroxydigitoxigenin,Desoxostrophanthidin,杠柳苷元
Target: Others
3-Hydroxyphenylacetic acid
Cat.No: T4829
Synonym:
Target: Others, Endogenous Metabolite
4-Methylumbelliferone
Cat.No: T1391
Synonym: Hymecromone,4-MU,胆通
Target: Others
Nicotiflorin
Cat.No: T6S1294
Synonym: Nictoflorin,Kaempferol-3-O-Rutinoside,山奈酚-3-O-芸香糖苷,Nicotifloroside
Target: Others
Isofraxidin
Cat.No: T5S0045
Synonym: 6,8-Dimethoxyumbelliferone,异秦皮啶,Phytodolor,异嗪皮啶
Target: MMP, ERK, p38 MAPK, TLR, COX
[6]-Gingerol
Cat.No: T3405
Synonym: 6-Gingerol,gingerol,(S)-(+)-[6]Gingerol,6-姜酚
Target: Apoptosis, AMPK
Questiomycin A
Cat.No: T36818
Synonym:
Target: GPR, Antibacterial
Magnoloside B
Cat.No: TN7134
Synonym:
Target: Glucosidase
1,3,7-Trimethyluric acid
Cat.No: T19792
Synonym:
Target: Others
3,4-O-Isopropylidene-shikimic acid
Cat.No: TN1238
Synonym: 3,4-O-异亚丙基莽草酸,3,4-O-Isopropylidene shikimic acid
Target: NOS, NO Synthase
Tigogenin
Cat.No: T5751
Synonym:
Target: Others
Ilexsaponin A
Cat.No: T2S0500
Synonym: 毛冬青皂苷A,毛冬青皂苷甲,Ilexsaponin A1
Target: Others
Traumatic Acid
Cat.No: T4454
Synonym: Dodec-2-Enedioic Acid,2E-Dodecenedioic Acid,愈伤酸,Trans-2-Dodecenedioic Acid
Target: Antioxidant
Indican
Cat.No: T19866
Synonym: NSC-87517,3-Indoxyl-beta-D-glucopyranoside,3-吲哚基-beta-D-吡喃葡萄糖苷,NSC 87517,NSC87517,Indoxyl-β-D-glucoside
Target: OAT, MRP
Zeaxanthin
Cat.No: TMS2180
Synonym: Anchovyxanthin,All-Trans-Zeaxanthin,玉米
Target: Antioxidant, Endogenous Metabolite
Cinnamtannin B-1
Cat.No: T25253
Synonym: Cinnamtannin B1 (constituent of cinnamomum verum bark),LDN 0022358,LDN-0022358,LDN0022358,肉桂单宁B-1
Target: Antioxidant, COX
Neotuberostemonine
Cat.No: T4953
Synonym:
Target: NOS
Cistanoside A
Cat.No: T5S0285
Synonym: 肉苁蓉苷 A,肉苁蓉苷A
Target: Others
Salvianolic acid D
Cat.No: TN2173
Synonym: (R,E)-2-((3-(2-(carboxymethyl)-3,4-dihydroxyphenyl)acryloyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid,丹酚酸D,丹酚酸 D
Target: Others
Ecliptasaponin A
Cat.No: T2S0690
Synonym: 早莲苷 A,旱莲苷A,Echinocystic acid-3-o-glucoside
Target: Others
Incensole
Cat.No: TWS1563
Synonym:
Target: Others
(+)-(3R,8S)-Falcarindiol
Cat.No: T5S1285
Synonym: Falcarindiol,镰叶芹二醇
Target: Others
Laminaran
Cat.No: T15705
Synonym: β-1,3-Glucan
Target:
Pseudoginsenoside F11
Cat.No: T3920
Synonym: Ginsenoside A1,拟人参皂苷 F11,拟人参皂苷F11
Target: Others, Endogenous Metabolite
Meloside A
Cat.No: TN1921
Synonym: 异牡荆素-2''-O-葡萄糖苷,Isovitexin 2''-O-glucoside,Isovitexin 2''-O-β-D-glucoside
Target: Others
Hamamelitannin
Cat.No: TN1722
Synonym:
Target: Antifection
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Cat. No. Product Name Species Expression System
TMPK-01246 GDF-15 Protein, Mouse, Recombinant (His)

MIC1,Placental TGF-beta,Placental TGF-β,PTGF-beta,PTGFBPTGF-...

Mouse E. coli
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Mouse, Rec...
TMPJ-01172 IL-17 Protein, Mouse, Recombinant (His)

CTLA8,IL-17,IL-17A,Interleukin-17A,CTLA-8,Cytotoxic T-Lympho...

Mouse HEK293 Cells
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid sequence identity with human and rat IL-17A, respectively. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumato...
TMPK-00564 TNFR1/CD120a/TNFRSF1A Protein, Cynomolgus, Recombinant (His)

TBP1,TNF-RI,TNFAR,p55,p60,p55-R,TNF-R55,FPF,TNF-R1,TNFR1-d2,...

Cynomolgus HEK293 Cells
Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2. In the setting of acute injury, selective inhibition of TNFR1 is predicted to attenuate the cell death and inflammation associated with TNF-α, while sparing or potentiating the protective effects of TNFR2 signalling.
TMPH-03275 Cytoglobin Protein, Rat, Recombinant (His & Myc)

Stellate cell activation-associated protein,Stap,CYGB,Cytogl...

Rat E. coli
May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer. Plays a role in the development of liver fibrosis. Has a peroxidase activity.
TMPH-03109 GPX5 Protein, Pig, Recombinant (His & Myc)

GPX5,Epididymis-specific glutathione peroxidase-like protein...

Sus scrofa (Pig) P. pastoris (Yeast)
May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. Since the purified porcine enzyme has very little activity towards hydrogen peroxide or organic hydroperoxides the protective effect is not likely to be exerted by its enzymatic activity. Instead, may protect sperm from premature acrosome reaction in the epididymis by binding to lipid peroxides, which might otherwise interact with phospholipase A2 and induce the acrosome reaction. GPX...
TMPH-01296 GPX5 Protein, Human, Recombinant (GST & His)

GPX5,Glutathione peroxidase 5,Epididymal secretory glutathio...

Human E. coli
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids.
TMPH-01706 Mucin-16/MUC16 Protein, Human, Recombinant (His)

Ovarian carcinoma antigen CA125,Ovarian cancer-related tumor...

Human HEK293 Cells
Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Mucin-16/MUC16 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 30.5 kDa and the accession number is Q8WXI7.
TMPH-03108 GPX5 Protein, Pig, Recombinant (E. coli, His & Myc)

GPX5,Glutathione peroxidase 5,Epididymis-specific glutathion...

Sus scrofa (Pig) E. coli
May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. Since the purified porcine enzyme has very little activity towards hydrogen peroxide or organic hydroperoxides the protective effect is not likely to be exerted by its enzymatic activity. Instead, may protect sperm from premature acrosome reaction in the epididymis by binding to lipid peroxides, which might otherwise interact with phospholipase A2 and induce the acrosome reaction. GPX...
TMPK-00444 SARS-COV-2 Spike S1 NTD Protein (His & Flag)

S1 protein NTD,Spike glycoprotein Subunit1 NTD,S glycoprotei...

SARS-CoV-2 HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike S1 NTD Protein (His & Flag) is expressed in HEK293 mammalian cells with C-His-Flag tag. The predicted molecular weight is 35 kDa and the accession number is A...
TMPK-00910 SARS Spike S1 Protein (His & Avi)

S1 protein,S glycoprotein Subunit1,Spike protein S1,Spike,S1...

SARS HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS Spike S1 Protein (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 75.9 kDa and the accession number is P59594.
TMPK-00437 SARS-COV-2 Spike RBD Protein (His & Avi)

S glycoprotein RBD,Spike protein RBD,S protein RBD

SARS-CoV-2 HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike RBD Protein (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27 kDa and the accession number is A0A6G7...
TMPK-00433 SARS-COV-2 Spike S1 Protein (hFc & Avi), Biotinylated

S1 protein,Spike,S1 protein,Spike protein S1,S glycoprotein ...

SARS-CoV-2 HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike S1 Protein (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 102.6 kDa and the accession ...
TMPH-02587 CIRBP Protein, Mouse, Recombinant (His)

CIRP,A18 hnRNP,Glycine-rich RNA-binding protein CIRP,CIRBP,C...

Mouse E. coli
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Promotes assembly of stress granules (SGs), when overexpressed. Seems to play an essential role in cold-induced suppression of cell proliferation. Acts as a translational repressor. Acts as a translational activator. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN.
TMPK-00438 SARS-COV-2 Spike S Trimer Protein (His & Avi)

COVID-19,S protein,S glycoprotein,Spike glycoprotein

SARS-CoV-2 HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike S Trimer Protein (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 136.6 kDa and the accession number i...
TMPY-02128 Serpin B1 Protein, Human, Recombinant (His)

HEL57,serpin peptidase inhibitor, clade B (ovalbumin), membe...

Human Baculovirus Insect Cells
SerpinB1 is an endogenous inhibitor of serine proteases recognized for its anti-inflammatory and host-protective properties. Serum SerpinB1 levels are elevated in patients with type 2 diabetes compared with that in healthy subjects and are negatively correlated with serum LDL-C. serpinB1 as an endogenous protein that can potentially be harnessed to enhance functional beta cell mass in patients with diabetes.
TMPJ-01076 FKBP4 Protein, Human, Recombinant (His)

FKBP4,HSP-binding immunophilin,immunophilin FKBP52,FK506-bin...

Human E. coli
FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.
TMPJ-00155 Mucin-1/MUC1 Protein, Human, Recombinant (hFc&Avi), Biotinylated

Polymorphic epithelial mucin,KL-6,Cancer antigen 15-3,PEMT,P...

Human HEK293 Cells
Mucin-1, is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. MUC-1 exclusively located in the apical domain of the plasma membrane ...
TMPK-00432 SARS-COV-2 Spike S1 Protein (hFc & Avi)

Spike protein S1,S glycoprotein Subunit1,S1 protein,Spike,S1...

SARS-CoV-2 HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike S1 Protein (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 102.6 kDa and the accession number is A0A6...
TMPK-00434 SARS-COV-2 Spike RBD Protein (hFc & Avi), Biotinylated

S protein RBD,S glycoprotein RBD,Spike protein RBD

SARS-CoV-2 HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike RBD Protein (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 51.7 kDa and the accession ...
TMPK-00911 SARS Spike RBD Protein (His & Avi)

S protein RBD,Spike protein RBD,S glycoprotein RBD

SARS HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS Spike RBD Protein (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27.9 kDa and the accession number is P59594.
TMPK-00442 SARS-COV-2 (Omicron B.1.1.529) Spike S Trimer Protein (His & Avi), Biotinylated

S glycoprotein,COVID-19,S protein,Spike glycoprotein

SARS-CoV-2 HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 (Omicron B.1.1.529) Spike S Trimer Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 13...
TMPH-01708 Mucin-2/MUC2 Protein, Human, Recombinant (His)

MUC2,Mucin-2,Intestinal mucin-2

Human E. coli
Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer. Mucin-2/MUC2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 28.8 kDa an...
TMPK-01244 GDF-15 Protein, Mouse, Recombinant (hFc)

PTGFBPTGF-beta,PTGFB,PLAB,NAG-1,Placental TGF-β,RG-1,GDF15,G...

Mouse HEK293 Cells
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Mouse, Rec...
TMPK-00439 SARS-COV-2 Spike RBD Protein (His & Avi), Biotinylated

S protein RBD,S glycoprotein RBD,Spike protein RBD

SARS-CoV-2 HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike RBD Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27 kDa and the accession nu...
TMPK-00912 SARS Spike RBD Protein (His & Avi), Biotinylated

S glycoprotein RBD,S protein RBD,Spike protein RBD

SARS HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS Spike RBD Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27.9 kDa and the accession number...
TMPK-00908 SARS Spike S1 Protein (hFc & Avi)

Spike protein S1,S1 protein,Spike,S1 protein,S glycoprotein ...

SARS HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS Spike S1 Protein (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 100.6 kDa and the accession number is P59594.
TMPK-00913 SARS Spike S1 Protein (His & Avi), Biotinylated

Spike protein S1,S glycoprotein Subunit1,S1 protein,Spike,S1...

SARS HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS Spike S1 Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 75.9 kDa and the accession number ...
TMPK-00440 SARS-COV-2 Spike S1 Protein (His & Avi), Biotinylated

S1 protein,S glycoprotein Subunit1,Spike,S1 protein,Spike pr...

SARS-CoV-2 HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike S1 Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 77.9 kDa and the accession n...
TMPK-00909 SARS Spike S1 Protein (hFc & Avi), Biotinylated

Spike protein S1,S glycoprotein Subunit1,Spike,S1 protein,S1...

SARS HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS Spike S1 Protein (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 100.6 kDa and the accession number...
TMPH-03158 PAD Protein, Porphyromonas gingivalis, Recombinant (His)

Peptidylarginine deiminase

Porphyromonas gingivalis E. coli
Deiminates the guanidino group of C-terminal arginine residues on a variety of peptides, including the vasoregulatory peptide-hormone bradykinin, to yield ammonia and a citrulline residue. May promote the growth of the pathogen in the periodontal pocket by producing ammonia, ammonia having a protective effect during acidic cleaning cycles in the mouth. PAD Protein, Porphyromonas gingivalis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weig...
TMPY-04398 MST1 Protein, Human, Recombinant (His)

serine/threonine kinase 4,KRS2,MST1,TIIAC,YSK3

Human Baculovirus Insect Cells
Dysregulation of MST1/STK4, a key kinase component of the Hippo-YAP pathway, is linked to the etiology of many cancers with poor prognosis. STK4/Hippo pathway may have important therapeutic implications for cancer. The tumor suppressor serine/threonine-protein kinase 4 (STK4) differentially regulates TLR3/4/9-mediated inflammatory responses in macrophages and thereby is protective against chronic inflammation-associated Hepatocellular carcinoma (HCC). STK4 has potential as a diagnostic biomarker...
TMPJ-00860 HTN3 Protein, Human, Recombinant

HTN3,Histidine-rich protein 3,Histatin-3,Basic histidine-ric...

Human E. coli
HTN3 belongs to the histatin/statherin family. Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities. Post-translational proteolytic processing results in many histatins: e.g., histatins 4-6 are derived from histatin 3 by proteolysis. Histatins 1 and 3 are primary products of HIS1and HIS2 alleles, respectively. Histatins are be...
TMPK-00665 GDF-15 Protein, Cynomolgus, Recombinant (His)

PTGFBPTGF-beta,PTGFBPTGF-β,MIC-1,NAG-1,MIC1,PTGF-beta,PTGF-β...

Cynomolgus E. coli
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Cynomolgus...
TMPK-00663 GDF-15 Protein, Cynomolgus, Recombinant (hFc)

PTGF-β,GDF-15,NAG-1,PTGF-beta,PDF,PTGFBPTGF-beta,GDF15,Place...

Cynomolgus HEK293 Cells
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Cynomolgus...
TMPY-02201 Peroxiredoxin 6 Protein, Human, Recombinant (His)

p29,PRX,1-Cys,HEL-S-128m,peroxiredoxin 6,NSGPx,AOP2,aiPLA2

Human E. coli
PRDX6, a member of antioxidant protein superfamily, plays an important role in oxidative stress, catabolism of lipids and phospholipid lipisomes. Peroxiredoxin 6 (PRDX6) is involved in redox regulation of the cell and is thought to be protective against oxidant injury. Peroxiredoxin 6 (PRDX6) is a bifunctional protein with both glutathione peroxidase (GPx) and iPLA2 activities,which are concomitantly increased with the expression of PRDX6. PRDX6 promoted lung tumor growth in an in vivo allograft...
TMPK-00191 PILRA Protein, Mouse, Recombinant (hFc)

PILR-α,FDF03,PILRA,PILR-alpha,PILRalpha,PILRα

Mouse HEK293 Cells
Alzheimer's disease (AD) is a neurodegenerative disease characterized by a progressive decline in cognitive performance; Mild Cognitive Impairment (MCI) is instead an objective decline in cognitive performance that does not reach pathology. Paired immunoglobulin-like type 2 receptor alpha (PILRA) is a cell surface inhibitory receptor that was recently suggested to be involved in AD pathogenesis. In particular, the arginine-to-glycine substitution in position 78 (R78, rs1859788) was shown to be p...
TMPK-00441 SARS-COV-2 Spike S Trimer Protein (His & Avi), Biotinylated

Spike glycoprotein,S glycoprotein,S protein,COVID-19

SARS-CoV-2 HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike S Trimer Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 136.6 kDa and the acce...
TMPK-00443 SARS-COV-2 (Omicron B.1.1.529) Spike S1 Protein (His & Avi), Biotinylated

Spike,S1 protein,S glycoprotein Subunit1,S1 protein,Spike pr...

SARS-CoV-2 HEK293 Cells
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 (Omicron B.1.1.529) Spike S1 Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 77.94 kD...
TMPY-00554 CHRNB3 Protein, Human, Recombinant (His)

cholinergic receptor, nicotinic, beta 3 (neuronal),cholinerg...

Human HEK293 Cells
Cholinergic nicotinic receptor (CHRN) gene family has been known to mediate the highly additive effects of nicotine in the body, and implicated nicotine dependence (ND) and related phenotypes. Cigarette smoking is protective in Parkinson's disease (PD), possibly because of nicotine action on brain nicotinic-acetylcholine receptors. The beta3 nicotinic-acetylcholine receptor subunit (encoded by CHRNB3) is depleted in the striatum of PD patients and associated with nicotine dependence. CHRNB3 Prot...
TMPY-04195 CHRNB3 Protein, Human, Recombinant (hFc)

cholinergic receptor, nicotinic, β 3 (neuronal),cholinergic ...

Human HEK293 Cells
Cholinergic nicotinic receptor (CHRN) gene family has been known to mediate the highly additive effects of nicotine in the body, and implicated nicotine dependence (ND) and related phenotypes. Cigarette smoking is protective in Parkinson's disease (PD), possibly because of nicotine action on brain nicotinic-acetylcholine receptors. The beta3 nicotinic-acetylcholine receptor subunit (encoded by CHRNB3) is depleted in the striatum of PD patients and associated with nicotine dependence. CHRNB3 Prot...
TMPY-02924 RGS1 Protein, Human, Recombinant (His)

1R20,IER1,BL34,HEL-S-87,regulator of G-protein signaling 1,I...

Human E. coli
RGS1 (regulator of G-protein signaling 1) has been associated with multiple autoimmune disorders including type I diabetes. RGS1 desensitizes the chemokine receptors CCR7 and CXCR4 that are critical to the localization of T and B cells in lymphoid organs. RGS1 expression may be a prognostic marker for risk stratification and a promising target for the development of a new Multiple myeloma (MM) therapy. The markers in the RGS1 gene might be in linkage disequilibrium with a protective allele that ...
TMPK-01245 GDF-15 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated

RG-1,GDF15,Placental TGF-beta,GDF-15,PTGFBPTGF-beta,NAG-1,PT...

Mouse HEK293 Cells
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am...
TMPK-00197 GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (H202D, hFc), Biotinylated

Placental TGF-β,GDF15,RG-1,MIC-1,PTGFB,PTGF-beta,PDF,PTGF-β,...

Human HEK293 Cells
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am...
TMPY-03983 CIRBP Protein, Human, Recombinant (His)

cold inducible RNA binding protein,CIRP

Human E. coli
CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a wide array of cellular stresses, including short wavelength ultraviolet light (UVC), at the transcriptional and post-translational level. It acts as a translational activator.CIRBP can bind the 3 translated region of specific transcripts to stabilize them and facilitate their transport to ribosomes for...
TMPY-03122 GBP2 Protein, Human, Recombinant (His)

guanylate binding protein 2,GBP2

Human HEK293 Cells
GBP-2 belongs to the guanylate-binding protein (GBP) family. GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). As GTPases induced by IFN-gamma (Interferon-inducible GTPase), they are key to the protective immunity against microbial and viral pathogens. GBP-2 is a GTPase that converts GTP to GDP and GMP. It binds GTP, GDP and GMP. GBP-2 hydrolyzes GTP very efficiently. GDP rather than GMP is the major reaction product. GBP-2 is induced by interf...
TMPJ-00859 AREG Protein, Human, Recombinant

AR,CRDGF,Amphiregulin,Colorectum Cell-Derived Growth Factor,...

Human E. coli
Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is expressed in a variety of tissues including ovary, placenta, lung, kidney, stomach, colon, and breast. It is related to Epidermal Growth Factor (EGF) and Transforming Growth Factor Alpha (TGF-alpha). As an EGF-related growth factor, AREG interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits...
TMPJ-01287 Sialidase-1 Protein, Human, Recombinant (His)

NEU1,NANH,Lysosomal Sialidase,G9 Sialidase,Sialidase-1,N-Ace...

Human HEK293 Cells
Sialidase-1 belongs to the N-acetyl-a neuraminidase family. Sialidase-1 is expressed in many tissues; it is highly expressed in the pancreas, and weakly expressed in the brain. Sialidase-1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. Deficiencies in the human enzyme Sialidase-1 leads to sialidosis, a rare lysosomal storage disease. Sialidase-1 has been shown to interact with Cathepsin A (protective protein), β-galactosi...
TMPK-00664 GDF-15 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated

Placental TGF-beta,PTGFBPTGF-β,PLAB,MIC-1,GDF15,NAG-1,RG-1,P...

Cynomolgus HEK293 Cells
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am...
TMPK-00198 GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated

MIC-1,PTGFBPTGF-β,GDF15,PTGF-β,GDF-15,PTGF-beta,Placental TG...

Human HEK293 Cells
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am...
TMPY-03653 CTRL Protein, Human, Recombinant (His)

CTRL1,chymotrypsin-like

Human HEK293 Cells
CTRL-1, also known as chymotrypsin-like protease, belongs to thepeptidase S1 family. CTRL-1 contains 1peptidase S1 domain. Its expression is increased in preeclampsia (PE). Placental-derived chymotrypsin-like protease is responsible for inducing endothelial inflammatory phenotypic changes possibly by upregulation of cell adhesion molecule expressions, activation of cellular protease, and induction of extracellular regulated kinase phosphorylation. Activated microglia have been observed in variou...
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重组蛋白

GDF-15 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01246
Species: Mouse
Expression System: E. coli
IL-17 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01172
Species: Mouse
Expression System: HEK293 Cells
TNFR1/CD120a/TNFRSF1A Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00564
Species: Cynomolgus
Expression System: HEK293 Cells
Cytoglobin Protein, Rat, Recombinant (His & Myc)
Cat.No: TMPH-03275
Species: Rat
Expression System: E. coli
GPX5 Protein, Pig, Recombinant (His & Myc)
Cat.No: TMPH-03109
Species: Sus scrofa (Pig)
Expression System: P. pastoris (Yeast)
GPX5 Protein, Human, Recombinant (GST & His)
Cat.No: TMPH-01296
Species: Human
Expression System: E. coli
Mucin-16/MUC16 Protein, Human, Recombinant (His)
Cat.No: TMPH-01706
Species: Human
Expression System: HEK293 Cells
GPX5 Protein, Pig, Recombinant (E. coli, His & Myc)
Cat.No: TMPH-03108
Species: Sus scrofa (Pig)
Expression System: E. coli
SARS-COV-2 Spike S1 NTD Protein (His & Flag)
Cat.No: TMPK-00444
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS Spike S1 Protein (His & Avi)
Cat.No: TMPK-00910
Species: SARS
Expression System: HEK293 Cells
SARS-COV-2 Spike RBD Protein (His & Avi)
Cat.No: TMPK-00437
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-COV-2 Spike S1 Protein (hFc & Avi), Biotinylated
Cat.No: TMPK-00433
Species: SARS-CoV-2
Expression System: HEK293 Cells
CIRBP Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02587
Species: Mouse
Expression System: E. coli
SARS-COV-2 Spike S Trimer Protein (His & Avi)
Cat.No: TMPK-00438
Species: SARS-CoV-2
Expression System: HEK293 Cells
Serpin B1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02128
Species: Human
Expression System: Baculovirus Insect Cells
FKBP4 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01076
Species: Human
Expression System: E. coli
Mucin-1/MUC1 Protein, Human, Recombinant (hFc&Avi), Biotinylated
Cat.No: TMPJ-00155
Species: Human
Expression System: HEK293 Cells
SARS-COV-2 Spike S1 Protein (hFc & Avi)
Cat.No: TMPK-00432
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-COV-2 Spike RBD Protein (hFc & Avi), Biotinylated
Cat.No: TMPK-00434
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS Spike RBD Protein (His & Avi)
Cat.No: TMPK-00911
Species: SARS
Expression System: HEK293 Cells
SARS-COV-2 (Omicron B.1.1.529) Spike S Trimer Protein (His & Avi), Biotinylated
Cat.No: TMPK-00442
Species: SARS-CoV-2
Expression System: HEK293 Cells
Mucin-2/MUC2 Protein, Human, Recombinant (His)
Cat.No: TMPH-01708
Species: Human
Expression System: E. coli
GDF-15 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-01244
Species: Mouse
Expression System: HEK293 Cells
SARS-COV-2 Spike RBD Protein (His & Avi), Biotinylated
Cat.No: TMPK-00439
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS Spike RBD Protein (His & Avi), Biotinylated
Cat.No: TMPK-00912
Species: SARS
Expression System: HEK293 Cells
SARS Spike S1 Protein (hFc & Avi)
Cat.No: TMPK-00908
Species: SARS
Expression System: HEK293 Cells
SARS Spike S1 Protein (His & Avi), Biotinylated
Cat.No: TMPK-00913
Species: SARS
Expression System: HEK293 Cells
SARS-COV-2 Spike S1 Protein (His & Avi), Biotinylated
Cat.No: TMPK-00440
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS Spike S1 Protein (hFc & Avi), Biotinylated
Cat.No: TMPK-00909
Species: SARS
Expression System: HEK293 Cells
PAD Protein, Porphyromonas gingivalis, Recombinant (His)
Cat.No: TMPH-03158
Species: Porphyromonas gingivalis
Expression System: E. coli
MST1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04398
Species: Human
Expression System: Baculovirus Insect Cells
HTN3 Protein, Human, Recombinant
Cat.No: TMPJ-00860
Species: Human
Expression System: E. coli
GDF-15 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00665
Species: Cynomolgus
Expression System: E. coli
GDF-15 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPK-00663
Species: Cynomolgus
Expression System: HEK293 Cells
Peroxiredoxin 6 Protein, Human, Recombinant (His)
Cat.No: TMPY-02201
Species: Human
Expression System: E. coli
PILRA Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-00191
Species: Mouse
Expression System: HEK293 Cells
SARS-COV-2 Spike S Trimer Protein (His & Avi), Biotinylated
Cat.No: TMPK-00441
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-COV-2 (Omicron B.1.1.529) Spike S1 Protein (His & Avi), Biotinylated
Cat.No: TMPK-00443
Species: SARS-CoV-2
Expression System: HEK293 Cells
CHRNB3 Protein, Human, Recombinant (His)
Cat.No: TMPY-00554
Species: Human
Expression System: HEK293 Cells
CHRNB3 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04195
Species: Human
Expression System: HEK293 Cells
RGS1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02924
Species: Human
Expression System: E. coli
GDF-15 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated
Cat.No: TMPK-01245
Species: Mouse
Expression System: HEK293 Cells
GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (H202D, hFc), Biotinylated
Cat.No: TMPK-00197
Species: Human
Expression System: HEK293 Cells
CIRBP Protein, Human, Recombinant (His)
Cat.No: TMPY-03983
Species: Human
Expression System: E. coli
GBP2 Protein, Human, Recombinant (His)
Cat.No: TMPY-03122
Species: Human
Expression System: HEK293 Cells
AREG Protein, Human, Recombinant
Cat.No: TMPJ-00859
Species: Human
Expression System: E. coli
Sialidase-1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01287
Species: Human
Expression System: HEK293 Cells
GDF-15 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated
Cat.No: TMPK-00664
Species: Cynomolgus
Expression System: HEK293 Cells
GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
Cat.No: TMPK-00198
Species: Human
Expression System: HEK293 Cells
CTRL Protein, Human, Recombinant (His)
Cat.No: TMPY-03653
Species: Human
Expression System: HEK293 Cells
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Cat. No. Product Name Target Signaling Pathways
TMIJ-0119 Pitavastatin-d4 Sodium Salt

Pitavastatin-d4 Sodium Salt 是 Pitavastatin Sodium Salt 的氘代化合物。Pitavastatin Sodium Salt 的 CAS 号为 574705-92-3。

同位素标记化合物

Pitavastatin-d4 Sodium Salt
Cat.No: TMIJ-0119
Synonym:
Target:
TargetMol Loading
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