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128

抑制剂 & 化合物

17

天然产物

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化合物库

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4

同位素标记化合物

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Cat. No.	Product Name
L1200	表观遗传库		953 compounds
	953 种表观遗传学研究相关的生物活性小分子的特有集合，用于表观遗传学研究及其相关的检测和高通量、高内涵筛选；

化合物库

表观遗传库

Cat.No: L1200

Compounds: 953

Cat. No.	Product Name	Target	Signaling Pathways
T14057	6-CFDA 6-羧基荧光素二醋酸,6-Carboxyfluorescein diacetate	Others	Others
	6-CFDA (6-Carboxyfluorescein diacetate) 是可用于流式细胞术和荧光显微镜的荧光探针，也可以用于活体多光子显微镜研究动物肝胆代谢。
T18894	5(6)-CFDA CFDA,5-(6)-Carboxyfluorescein diacetate,5(6)-羧基荧光素二乙酸酯	Others	Others
	5(6)-CFDA (5-(6)-Carboxyfluorescein diacetate) 是具有细胞渗透性的胺反应型绿色荧光探针(λex: 492 nm; λem: 517 nm)，可用于细胞染色分析。
T21231	Almotriptan 阿莫曲坦,LAS 31416,阿莫曲普坦	5-HT Receptor	GPCR/G Protein; Neuroscience
	Almotriptan (LAS 31416) 是一种用于研究偏头痛的5-HT1B/1D 受体激动剂。
T18993	Fluorescein di-beta-D-galactopyranoside FDG,Fluorescein di(β-D-galactopyranoside)	Others	Others
	Fluorescein di-beta-D-galactopyranoside (FDG) 是通过流式细胞术检测动植物中β-半乳糖苷酶的荧光底物，λex=485 nm，λem=535 nm。
T3616	Carbazochrome AC-17,Adrenostazin,Cromadrenal,Adona,Adchnon,卡巴克络,Adedolon	Others; Phospholipase	Metabolism; Others
	Carbazochrome (Adchnon) 是毛细管稳定剂，是抗出血剂，用于研究出血。
T6273	Vadimezan DMXAA,伐地美生,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404	Influenza Virus; VDA; STING; IFNAR	Angiogenesis; Immunology/Inflammation; Microbiology/Virology
	Vadimezan (DMXAA) 是一种血管破坏剂，一种鼠 STING 激动剂，也是一种细胞因子如 I 型 IFN 的诱导剂。Vadimezan 具有抗肿瘤活性，可以诱导肿瘤中的血流快速停止，但不影响正常组织中的血流。
T5039	Aminohippurate sodium Sodium 4-aminohippurate Hydrate,Sodium p-aminohippurate,4-氨基马尿酸钠盐,p-Aminohippuric acid sodium salt	Others	Others
	Aminohippurate sodium (Sodium p-aminohippurate) 是能够利用肾血浆流量测量肾脏医学测试的诊断剂。
T18896	5(6)-FITC Fluorescein 5(6)-isothiocyanate,异硫氰酸荧光素,Fluorescein isothiocyanate	Others	Others
	5(6)-FITC (Fluorescein isothiocyanate), or Fluorescein 5(6)-isothiocyanate, is a versatile amine-reactive derivative of fluorescein dye. It serves as an effective label for antibodies and other probes, finding utility in fluorescence microscopy, flow cytometry, and immunofluorescence-based assays such as ELISA and Western blotting.
T23535L	Xanthine amine congener trihydrochloride Xanthine amine congener trihydrochloride (96865-92-8 Free base)	Adenosine Receptor	GPCR/G Protein; Neuroscience
	Xanthine amine congener trihydrochloride 是一种有效的腺苷拮抗剂，可逆转由腺苷激动剂 N6-环己基腺苷产生的尿流量、钠排泄和心率的减少。
T9376	Nitroarginine N'-硝基-L-精氨酸,N'-Nitro-L-arginine	NO Synthase	Immunology/Inflammation
	Nitroarginine (N'-Nitro-L-arginine) 是一氧化氮合酶的竞争性抑制剂，可选择性减少流向肿瘤细胞的血流。
T13830	Propoxycaine hydrochloride Propoxycaine HCl	Sodium Channel	Membrane transporter/Ion channel
	Propoxycaine hydrochloride 是一种酯类局部麻醉剂，抑制电压门控的钠通道，可调节神经冲动，可诱导感觉丧失。Propoxycaine hydrochloride 可调节SPMVs脂质双层的流动。
T11318	Dopexamine hydrochloride 盐酸多培沙明,FPL60278AR	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Dopexamine hydrochloride (FPL60278AR) 是β2肾上腺素能受体激动剂。
T21263	Amlodipine maleate Amlodipine (+-)-form maleate,Amvaz	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Amlodipine maleate (Amvaz) 是一种具有口服活性的二氢吡啶类钙通道阻滞剂，通过阻滞电压依赖性 L 型钙通道，从而抑制钙离子内流。Amlodipine maleate 可用于研究高血压和癌症。
T39027	PKH 26 PKH26,PKH-26
	PKH 26 是一种有红荧光的膜染料，Ex/Em=551/567 nm。PKH 26 常用于流式细胞术，可测定 T 细胞介导的细胞毒性活性。
T77767L1	GLF16 HCl	Others	Others
	GLF16 HCl 是一种荧光团偶联的苏丹黑 B 类似物，可通过通过荧光显微镜和流式细胞术快速检测、分离和实时跟踪衰老细胞。
T78263	Anti-Mouse IFNAR1 Antibody (MAR1-5A3)	Antibiotic	Microbiology/Virology
	Anti-Mouse IFNAR1 Antibody (MAR1-5A3) 是一种中和 IFNAR1 的抗体，可与IFNAR1结合并阻断信号传导，可用于蛋白质印迹、免疫组化、流式细胞术、免疫细胞化学和 ELISA。
T14875	Indocyanine green Cardiogreen,IC Green,Foxgreen,吲哚菁绿	Others	Others
	Indocyanine green (Cardiogreen) 是低毒性荧光剂，普遍用于医学诊断，包括确定心输出量，肝功能和肝血流量，以及用于眼科血管造影。
T78393	C12FDG 5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside
	C12FDG (5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside) 作为一种亲脂性用于检测β-半乳糖活性的绿色荧光底物，是一种衰老标志物，常与流式细胞仪连用。
T22361	Mepivacaine Carbocaine	Sodium Channel	Membrane transporter/Ion channel
	Mepivacaine (Carbocaine) 是一种可用于局部麻醉的酰胺类化合物，可使人或动物短暂的失去自知觉。Mepivacaine 通过与神经细胞膜上特定的电压门控钠离子通道结合，抑制钠离子内流和膜去极化来发挥作用。Mepivacaine 适用于神经阻滞和硬膜外麻醉。
T36958	BODIPY 505/515
	BODIPY 505/515 是一种亲脂性荧光探针，可定位到细胞内的脂质体，已被用于标记脂滴。BODIPY 505/515 已被用于电子显微镜、外荧光显微镜、共聚焦显微镜以及各种藻类物种的流式细胞仪应用中。
T39518	PFB-FDGlu	Others	Others
	PFB-FDGlu 是一种溶酶体葡糖脑苷脂酶（GCase）底物，具有细胞渗透特异性，裂解后产生荧光素。PFB-FDGlu 通常与流式细胞仪结合使用，以单个细胞为基础测量活细胞中 GCase 的活性。
T40194	MeAIB α-(Methylamino)isobutyric acid	Others	Others
	MeAIB 是一种n -乙酰转移酶抑制剂，抑制SNAT2相关信号通路。MeAIB 是氨基酸转运系统a (ATA1)的特异性底物。氨基酸转运系统a (ATA1）以Na+流动调控短链中性氨基酸的摄取。
T15609	JC-1 CBIC2	Others	Others
	JC-1 (CBIC2) 是一种荧光亲脂性羰花青染料，用于测量线粒体膜电位。线粒体膜电位较高时，它在基质中汇聚形成聚合物，可以产生红色荧光(λex=585 nm，λem=590 nm)。线粒体膜电位较低时，它不能聚集在线粒体基质中，以单体形式存在产生绿色荧光(λex=510 nm，λem=527 nm)。
T2090	Lexibulin CYT-997	Apoptosis; Reactive Oxygen Species; Microtubule Associated	Apoptosis; Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB
	Lexibulin (CYT-997) 是一种微管蛋白聚集强效抑制剂，可诱导细胞凋亡，并诱导 GC 细胞中的线粒体ROS 生成。它对多种癌细胞的 IC50 值为 10-100n M，在体内外具有高细胞毒性和血管增生阻断作用。
T63980	BODIPY FL prazosin	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	BODIPY FL prazosin 是一种高效的 α1-肾上腺素拮抗剂，抑制 α1a-AR 和 α1b-AR. BODIPY FL prazosin 是一种荧光配体（λEx(nm)/ λEm (nm)： 485/535），常与流式细胞术或共聚焦激光扫描显微镜一起研究α1-肾上腺素亚型和细胞成像。
T0957	Isradipine PN 200-110,伊拉地平	Calcium Channel; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism
	Isradipine (PN 200-110) 是一种二氢吡啶类钙通道阻滞剂，具有抗高血压和血管扩张活性。它是一种具有口服活性的 L 型钙通道阻滞剂，也是一种潜在可行的帕金森病神经保护剂。
T2535	Ivabradine hydrochloride 盐酸伊伐布雷定,S 16257-2,Ivabradine HCl	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Ivabradine hydrochloride (S 16257-2) 是一种可口服的，超极化激活的环核苷酸门控离子通道通道阻滞剂。
T4433	6-CFDA N-succinimidyl ester Carboxyfluorescein diacetate succinimidyl	Others	Others
	6-CFDA N-succinimidyl ester (Carboxyfluorescein diacetate succinimidyl) 能够自发且不可逆地与游离胺结合。在流式细胞术实验中用于追踪哺乳动物细胞和细菌的细胞分裂。与多种细胞透化剂结合使用，作为一种有效的、非破坏性的荧光染料，可快速检测细菌细胞。
T2130	Propidium Iodide PI,碘化丙啶,碘化丙啶（PI）	Others	Others
	Propidium Iodide (PI) 是一种可用于细胞染色的红色荧光染料，适用于荧光显微镜、共聚焦显微镜、流式细胞仪以及荧光计分析。在水溶液中，Propidium Iodide 的 Ex/Em 为 493/636 nm；与核酸结合后，PI-核酸的 Ex/Em 变为 535/617 nm，同时荧光信号增强 20-30 倍。
T3536	AZD1283	P2Y Receptor	GPCR/G Protein; Neuroscience
	AZD1283是P2Y12受体拮抗剂，EC50为3.0 ug/kg/min，结合的IC50为11 nM。它剂量依赖性地诱导血流量增加和抑制 ADP 诱导的血小板聚集，抗血栓形成的 ED50 值分别为 3.0 和 10 μg/kg/min。
T31206	Darexaban YM 150,Darexaban, Tanexaban,YM150	Factor Xa	Metabolism
	Darexaban (Tanexaban, YM-150) 是选择性的、口服具有活力的 Xa 因子 (FXa) 抑制剂，IC50=54.6 nM。它对其他相关丝氨酸蛋白酶(如胰蛋白酶、凝血酶和激肽释放酶)具有高选择性。它具有抗凝和抗血栓形成作用。
T2671	Regadenoson CVT-3146,瑞加德松,Lexiscan	Adenosine Receptor	GPCR/G Protein; Neuroscience
	Regadenoson (CVT-3146) 是一种腺苷衍生物和选择性 A2A 腺苷受体激动剂，具有冠状动脉舒张活性，对大鼠和猪腺苷 A2A 受体的Ki 分别为 290 和 1120 nM。它是血管扩张剂，可增加啮齿动物血脑屏障的通透性。
T0096	Vardenafil 伐地那非,Vivanza,Levitra,Vardenafil hydrochloride	PDE	Metabolism
	Vardenafil (Vivanza) 是选择性、高效的、具有口服活性的磷酸二酯酶5抑制剂，IC50=0.7 nM。它能够非竞争性地抑制环磷酸鸟苷水解，从而提高 cGMP 水平。它对 PDE1 (180 nM)，PDE6 (11 nM)，PDE2，PDE3，PDE4 (>1000 nM) 具有选择性。它可用于研究勃起功能障碍。
T14017	2-NBDG 2-(N-7-硝基-2,1,3-苯并恶二唑-4-氨基)-2-脱氧-D-葡萄糖	Others	Others
	2-NBDG 是一种荧光指示剂 (λex=467 nm，λem=542 nm)，是一种荧光 D-葡萄糖类似物。2-NBDG 可用于监测活细胞和组织中的葡萄糖吸收，可以通过实时共聚焦、高分辨率或宽视场荧光显微镜和流式细胞术进行监测。
T27015	Cicrotoic acid	Others	Others
	Cicrotoic acid, a biochemical drug, acts on bile flow and liquid composition of human bile.
T32426	KT 1 KT-1,KT1	Others	Others
	KT 1 decreased aortic pressure, renal blood flow, left ventricular enddiastolic pressure and resistances of total peripheral, vertebral, coronary and renal vasculatures and increased aortic blood flow, vertebral blood flow, coronary blood flow, peak posit
T30907	Chromonar hydrochloride Antiangor,chromonar HCl,Karbokromen	Others	Others
	Chromonar Hydrochloride is a coronary vasodilator that increases transwall blood flow.
T27351	Fostedil KB-944,KB944,A 53986,KB 944,A-53986,BRN 3626546	Others	Others
	Fostedil is a calcium channel antagonist. KB-944 increased regional segment function in normal and ischemic regions and maintained distal coronary artery perfusion pressure, coronary flow and transmural regional myocardial blood flow during partial corona
T30602	Bts 39542 Bts-39542,Bts39542	Others	Others
	Bts 39542 is a diuretic that plays a major role in the Henle circulation and increases renal blood flow without affecting glomerular filtration rate.
T14058	6-FITC 6-异硫氰酸荧光素,6-Fluorescein Isothiocyanate	Others	Others
	6-Fluorescein Isothiocyanate (6-FITC) is a fluorescein derivative widely employed in applications such as flow cytometry.
T30444	Bicisate dihydrochloride Bicisate HCl	Others	Others
	Bicisate dihydrochloride is usually complex with technetium Tc99m to measure cerebral blood flow with single-photon emission computed tomography (SPECT).
T34895	Tocamphyl Tocanfil,Biliphorin,Gallogen	Others	Others
	Tocamphyl is a cholagogic agent that stimulates pancreatic exocrine and bile flow when administered in the duodenum.
T29792	AK-135	Others	Others
	AK-135 is a derivative of 1,4-naphthoquinone (Menadione). AK-135 has been shown to restore the electron flow in defective respiratory chain (hypoxia or rotenone) systems more effectively than Menadione.
T30444L	Bicisate (Free base) Bicisate	Others	Others
	Bicisate is usually complex with technetium Tc99m for its usage as a tracer to measure cerebral blood flow with single-photon emission computed tomography (SPECT).
T21185	CEP03 CEP 03,CEP-03	Others	Others
	CEP03 enhances EC/EPC proliferation, tubelike formation, and wound-healing efficiency, leading to promote angiogenesis and significantly improve blood flow perfusion recovery in the ischemic hind limbs of mice.
T39795	Tricarbonyldichlororuthenium(II) dimer CORM-2	Others	Others
	Tricarbonyldichlororuthenium(II) dimer, a pharmacological CO donor, prevents ischemia/reperfusion (I/R)-induced oxidative damage to the gastric mucosa by enhancing gastric blood flow (GBF) and reducing DNA oxidation and systemic inflammatory response.
T37317	Fluo-3 (sodium salt)
	Fluo-3 is a fluorescent calcium indicator commonly used in flow cytometry and cell-based experiments to detect changes in intracellular calcium levels. Its absorption maximum at 506 nm makes it compatible with excitation at 488 nm by argon-ion laser sources. Fluo-3 provides intense fluorescence upon binding calcium, detected at a maximum emission at 526 nm which can be monitored by FL1 (green, 525 nm band pass) sensors in flow cytometry.
T24690	Pyrromecaine HCl Bumecaine hydrochloride,Pyrromecaine	Others	Others
	Pyrromecaine is a local anesthetic used for surface anesthesia. Pyromecaine has a wide spectrum of antiarrhythmic action, exerts a favorable effect on the contractility of the left ventricle, and on the myocardial blood flow following the ligation of the
T71988	Moxaverine hydrochloride	Others	Others
	Moxaverine hydrochloride is a derivative of papaverine, a phosphodiesterase inhibitor. Moxaverine has been studied in phase III of a clinical trial for the treatment of ocular blood flow in patients with age- related macular degeneration and primary open angle glaucoma.
T39546	Fluorescein tyramide	Others	Others
	Fluorescein tyramide is a widely utilized green fluorescent reagent (λ abs : 494 nm; λ em : 517 nm), primarily employed for tyramide signal amplification (TSA) in low-abundance IHC, ICC, in situ hybridization (FISH), and flow cytometry (FCM) applications.

化合物

Cat.No: T14057

Synonym: 6-羧基荧光素二醋酸,6-Carboxyfluorescein diacetate

Target: Others

Cat.No: T18894

Synonym: CFDA,5-(6)-Carboxyfluorescein diacetate,5(6)-羧基荧光素二乙酸酯

Target: Others

Cat.No: T21231

Synonym: 阿莫曲坦,LAS 31416,阿莫曲普坦

Target: 5-HT Receptor

Fluorescein di-beta-D-galactopyranoside

Cat.No: T18993

Synonym: FDG,Fluorescein di(β-D-galactopyranoside)

Target: Others

Cat.No: T3616

Synonym: AC-17,Adrenostazin,Cromadrenal,Adona,Adchnon,卡巴克络,Adedolon

Target: Others, Phospholipase

Cat.No: T6273

Synonym: DMXAA,伐地美生,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404

Target: Influenza Virus, VDA, STING, IFNAR

Aminohippurate sodium

Cat.No: T5039

Synonym: Sodium 4-aminohippurate Hydrate,Sodium p-aminohippurate,4-氨基马尿酸钠盐,p-Aminohippuric acid sodium salt

Target: Others

Cat.No: T18896

Synonym: Fluorescein 5(6)-isothiocyanate,异硫氰酸荧光素,Fluorescein isothiocyanate

Target: Others

Xanthine amine congener trihydrochloride

Cat.No: T23535L

Synonym: Xanthine amine congener trihydrochloride (96865-92-8 Free base)

Target: Adenosine Receptor

Cat.No: T9376

Synonym: N'-硝基-L-精氨酸,N'-Nitro-L-arginine

Target: NO Synthase

Propoxycaine hydrochloride

Cat.No: T13830

Synonym: Propoxycaine HCl

Target: Sodium Channel

Dopexamine hydrochloride

Cat.No: T11318

Synonym: 盐酸多培沙明,FPL60278AR

Target: Adrenergic Receptor

Amlodipine maleate

Cat.No: T21263

Synonym: Amlodipine (+-)-form maleate,Amvaz

Target: Calcium Channel

Cat.No: T39027

Synonym: PKH26,PKH-26

Cat.No: T77767L1

Target: Others

Anti-Mouse IFNAR1 Antibody (MAR1-5A3)

Cat.No: T78263

Target: Antibiotic

Indocyanine green

Cat.No: T14875

Synonym: Cardiogreen,IC Green,Foxgreen,吲哚菁绿

Target: Others

Cat.No: T78393

Synonym: 5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside

Cat.No: T22361

Synonym: Carbocaine

Target: Sodium Channel

Cat.No: T36958

Cat.No: T39518

Target: Others

Cat.No: T40194

Synonym: α-(Methylamino)isobutyric acid

Target: Others

Cat.No: T15609

Synonym: CBIC2

Target: Others

Cat.No: T2090

Synonym: CYT-997

Target: Apoptosis, Reactive Oxygen Species, Microtubule Associated

BODIPY FL prazosin

Cat.No: T63980

Target: Adrenergic Receptor

Cat.No: T0957

Synonym: PN 200-110,伊拉地平

Target: Calcium Channel, Autophagy

Ivabradine hydrochloride

Cat.No: T2535

Synonym: 盐酸伊伐布雷定,S 16257-2,Ivabradine HCl

Target: Adrenergic Receptor

6-CFDA N-succinimidyl ester

Cat.No: T4433

Synonym: Carboxyfluorescein diacetate succinimidyl

Target: Others

Propidium Iodide

Cat.No: T2130

Synonym: PI,碘化丙啶,碘化丙啶（PI）

Target: Others

Cat.No: T3536

Target: P2Y Receptor

Cat.No: T31206

Synonym: YM 150,Darexaban, Tanexaban,YM150

Target: Factor Xa

Cat.No: T2671

Synonym: CVT-3146,瑞加德松,Lexiscan

Target: Adenosine Receptor

Cat.No: T0096

Synonym: 伐地那非,Vivanza,Levitra,Vardenafil hydrochloride

Target: PDE

Cat.No: T14017

Synonym: 2-(N-7-硝基-2,1,3-苯并恶二唑-4-氨基)-2-脱氧-D-葡萄糖

Target: Others

Cat.No: T27015

Target: Others

Cat.No: T32426

Synonym: KT-1,KT1

Target: Others

Chromonar hydrochloride

Cat.No: T30907

Synonym: Antiangor,chromonar HCl,Karbokromen

Target: Others

Cat.No: T27351

Synonym: KB-944,KB944,A 53986,KB 944,A-53986,BRN 3626546

Target: Others

Cat.No: T30602

Synonym: Bts-39542,Bts39542

Target: Others

Cat.No: T14058

Synonym: 6-异硫氰酸荧光素,6-Fluorescein Isothiocyanate

Target: Others

Bicisate dihydrochloride

Cat.No: T30444

Synonym: Bicisate HCl

Target: Others

Cat.No: T34895

Synonym: Tocanfil,Biliphorin,Gallogen

Target: Others

Cat.No: T29792

Target: Others

Bicisate (Free base)

Cat.No: T30444L

Synonym: Bicisate

Target: Others

Cat.No: T21185

Synonym: CEP 03,CEP-03

Target: Others

Tricarbonyldichlororuthenium(II) dimer

Cat.No: T39795

Synonym: CORM-2

Target: Others

Fluo-3 (sodium salt)

Cat.No: T37317

Pyrromecaine HCl

Cat.No: T24690

Synonym: Bumecaine hydrochloride,Pyrromecaine

Target: Others

Moxaverine hydrochloride

Cat.No: T71988

Target: Others

Fluorescein tyramide

Cat.No: T39546

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T13302	Viquidil hydrochloride Quinotoxine hydrochloride	Others	Others
	Viquidil hydrochloride (Quinotoxine hydrochloride) 是奎尼丁的同分异构体，是一种脑血管扩张剂，具有抗血栓作用。
T3S1534	Secoxyloganin 断氧化马钱苷,幼枝含断氧化马钱子甙,金银花	Anti-infection	Microbiology/Virology
	Secoxyloganin 是从Lonicera japonicaThunb 提取得到，能够抑制血流量减少，具有抗过敏活性。
TN1328	7-Amino-4-methylcoumarin-3-acetic acid 7-氨基-4-甲基-3-香豆素醋酸,7-Amino-4-methylcoumarin	Others	Others
	7-Amino-4-methylcoumarin-3-acetic acid (7-Amino-4-methylcoumarin) 是荧光蛋白质标记剂，能够被紫外光(350 nm) 激活，可在蓝色区域 (440-460 nm) 发光。
T6263	Safflower-yellow	Others	Others
	Safflower-yellow 是从植物红花（Carthamus tinctorius）的花中提取的，作为中药已广泛用于治疗心脑血管疾病。
T19056	Safflower yellow Saffron powder,Carthamas yellow,红花黄	Others	Others
	Safflower yellow (Saffron powder) 是提取自植物红花的花中，可用于研究心脑血管疾病。
T7975	Rhodamine B 罗丹明B,Rhodamine B,罗丹明 B,Tetraethylrhodamine,Brilliant Pink B,Basic Violet 1,Rhodamine O	Others	Others
	Rhodamine B (Brilliant Pink B) 是荧光染料，常用于染色纺织品、肥皂、纸张、皮革和药品。
T1436	4-Aminohippuric Acid p-Aminohippuric acid,对氨基马尿酸	Amino Acids and Derivatives; Endogenous Metabolite	Metabolism
	4-Aminohippuric Acid 是诊断剂，能够用于肾脏检测，在肾血浆流量的测定中使用。
T2S2335	Dehydroevodiamine DHED,去氢吴茱萸碱	Others; NF-κB; COX; PGE Synthase; NO Synthase	Immunology/Inflammation; Neuroscience; NF-κB; Others
	Dehydroevodiamine (DHED) 是从吴茱萸中分离出的一种喹唑啉生物碱，可抑制 LPS 诱导的小鼠巨噬细胞中iNOS、COX-2、PGE2和NF-κB 的表达，对豚鼠心室肌细胞具有抗心律失常作用。
T0070	Pentoxifylline Oxpentifylline,PTX,己酮可可碱,BL-191	HIV Protease; PDE; Adenosine Receptor; Autophagy	Autophagy; GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Pentoxifylline (PTX) 是一种具有口服活性的磷酸二酯酶非选择性抑制剂，具有免疫调节、抗炎、抗纤溶、抗增殖和血液流变学改善作用。它可研究周围血管疾病、脑血管疾病和其他一些涉及局部微循环缺陷的疾病。
TN2080	Pinoresinol 松脂酚，松脂素,(+)-Pinoresinol	Apoptosis; NF-κB; CDK; p53	Apoptosis; Cell Cycle/Checkpoint; NF-κB
	Pinoresinol ((+)-Pinoresinol) 是一种植物来源的木质素，具有抗炎、保肝和杀真菌活性。它导致 CDK 抑制剂 p21(WAF1/Cip1) 在 mRNA 和蛋白质水平上调，抑制 NF-kappaB 和激活蛋白 1 。
T38248	2-Ethylpyrazine	Endogenous Metabolite; NO Synthase	Immunology/Inflammation; Metabolism
	2-Ethylpyrazine 存在与烘焙后的咖啡豆中，是一种挥发性化合物。2-Ethylpyrazine 通过内皮衍生的松弛因子的活动诱导血管舒张。2-Ethylpyrazine 通过内皮内皮NO 合酶的作用激活NO 合成。2-Ethylpyrazine 通过诱导NO 释放和增加外周血流量来诱导血管舒张。
T1626	Prostaglandin E1 前列地尔,PGE1,列腺素E1,Alprostadil	Endogenous Metabolite; Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation; Metabolism
	Prostaglandin E1 (Alprostadil) 是一种前列腺素受体配体，对小鼠 EP1、EP2、EP3、EP4和 IP 的 Ki 值分别为 36、10、1.1、2.1 和 33 nM。它诱导血管舒张并抑制血小板聚集，可作为血管扩张剂用于外周血管疾病的研究。
TN1367	Alismol 泽泻醇	Potassium Channel; Calcium Channel; PI3K	Membrane transporter/Ion channel; Metabolism; PI3K/Akt/mTOR signaling
	Alismol has antihypertensive action, it decreases cardiac output, heart rate and left ventricular pressure, but it increases coronary flow, it has been used for the prevention of anginal attacks.
TN4616	N-Methyltaxol C	Others	Others
	N-methyltaxol C and paclitaxel can produce a positive inotropic effect in papillary muscle, without alterations in the action potential. They can induced conduction arrhythmias and reduce coronary flow and left ventricular systolic pressure in the isolate
TN4277	Isocupressic acid	cAMP; P450; PKA	GPCR/G Protein; Metabolism; Tyrosine Kinase/Adaptors
	Isocupressic acid induces abortion in pregnant cows when ingested primarily during the last trimester, it decrease affects the angiogenesis of the female reproductive system, the decrease in blood flow and apoptosis of corpus luteum-derived endothelial ce
T74193	(R)-IDHP	Others	Others
	(R)-IDHP为IDHP异构体，属于丹参代谢物。该化合物能通过抑制血管平滑肌细胞电压依赖性钙通道与受体操作钙通道的Ca2+释放和Ca2+内流，发挥血管松弛作用，适用于心脑血管疾病研究。
T37770	Taurohyodeoxycholic acid	Others	Others
	Taurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid .1THDCA decreases the size and weight of human gallstonesin vitro. It increases bile flow, biliary cholesterol secretion, and biliary lipid secretion in rats.2Co-administration of THDCA with taurochenodeoxycholic acid prevents TCDCA-induced hepatotoxicity, increasing bile flow as well as biliary acid and phospholipid secretion in rats.3THDCA also reduces myeloperoxidase activity, expressi...

天然产物

Viquidil hydrochloride

Cat.No: T13302

Synonym: Quinotoxine hydrochloride

Target: Others

Cat.No: T3S1534

Synonym: 断氧化马钱苷,幼枝含断氧化马钱子甙,金银花

Target: Anti-infection

7-Amino-4-methylcoumarin-3-acetic acid

Cat.No: TN1328

Synonym: 7-氨基-4-甲基-3-香豆素醋酸,7-Amino-4-methylcoumarin

Target: Others

Safflower-yellow

Cat.No: T6263

Target: Others

Safflower yellow

Cat.No: T19056

Synonym: Saffron powder,Carthamas yellow,红花黄

Target: Others

Cat.No: T7975

Synonym: 罗丹明B,Rhodamine B,罗丹明 B,Tetraethylrhodamine,Brilliant Pink B,Basic Violet 1,Rhodamine O

Target: Others

4-Aminohippuric Acid

Cat.No: T1436

Synonym: p-Aminohippuric acid,对氨基马尿酸

Target: Amino Acids and Derivatives, Endogenous Metabolite

Dehydroevodiamine

Cat.No: T2S2335

Synonym: DHED,去氢吴茱萸碱

Target: Others, NF-κB, COX, PGE Synthase, NO Synthase

Cat.No: T0070

Synonym: Oxpentifylline,PTX,己酮可可碱,BL-191

Target: HIV Protease, PDE, Adenosine Receptor, Autophagy

Cat.No: TN2080

Synonym: 松脂酚，松脂素,(+)-Pinoresinol

Target: Apoptosis, NF-κB, CDK, p53

2-Ethylpyrazine

Cat.No: T38248

Target: Endogenous Metabolite, NO Synthase

Prostaglandin E1

Cat.No: T1626

Synonym: 前列地尔,PGE1,列腺素E1,Alprostadil

Target: Endogenous Metabolite, Prostaglandin Receptor

Cat.No: TN1367

Synonym: 泽泻醇

Target: Potassium Channel, Calcium Channel, PI3K

N-Methyltaxol C

Cat.No: TN4616

Target: Others

Isocupressic acid

Cat.No: TN4277

Target: cAMP, P450, PKA

Cat.No: T74193

Target: Others

Taurohyodeoxycholic acid

Cat.No: T37770

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-00807	Osteopontin Protein, Mouse, Recombinant (His) ETA-1,SPP1,OPN,Bone sialoprotein 1,BNSP,SPP-1,Osteopontin,Ne...	Mouse	HEK293 Cells
	Secreted phosphoprotein 1 (SPP1) expression in TAMs isolated from lung adenocarcinoma tissues and PMA-treated THP-1 cells were measured. Macrophage polarization was identified by flow cytometric analysis. Cell migration and apoptosis were assessed by Transwell migration assays and flow cytometric analysis, respectively. SPP1 is highly expressed in tumor tissues and TAMs isolated from patients with an advanced TNM stage, and also in PMA-treated THP-1 cells.
TMPY-04830	GAS6 Protein, Mouse, Recombinant (His) growth arrest-specific 6,Gas-6	Mouse	HEK293 Cells
	The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin K-dependent protein, plays a role in the survival, proliferation, migration, differentiation, adhesion, and apoptosis of cells. The growth arrest-specific 6 (GAS6) has been implicated in systemic inflammation and coagulation. Growth arrest-specific 6 (GAS6), plays a role in tumor...
TMPJ-00989	MTHFS Protein, Human, Recombinant (His) 5-formyltetrahydrofolate cyclo-ligase,10-methenyl-tetrahydro...	Human	E. coli
	5-formyltetrahydrofolate cyclo-ligase (MTHFS) belongs to the 5-formyltetrahydrofolate cyclo-ligase family. It is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, contributes to tetrahydrofolate metabolism. MTHFS helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. An increased activity of the encoded protein can result in an increas...
TMPK-00359	Endoglin/CD105 Protein, Human, Recombinant (His & Avi) CD105,ORW,ORW1,ENG,END,Endoglin,HHT1	Human	HEK293 Cells
	Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins. Endoglin is a vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature (PubMed:7894484). Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response...
TMPY-02640	FAM3B Protein, Human, Recombinant (hFc) PANDER,ORF9,PRED44,C21orf11,C21orf76,42056,family with seque...	Human	HEK293 Cells
	Pancreatic derived factor, also known as FAM3B, is an islet-specific secreted cytokine specifically expressed at high levels in the islets of Langerhans of the endocrine pancreas. FAM3B protein is present in alpha- and beta- cells of pancreatic islets, insulin-secreting beta-TC3 cells, and glucagon-secreting alpha-TC cells. FAM3B causes apoptosis of beta-cells as assessed by electron microscopy, annexin Ⅴ fluorescent staining, and flow-cytometric terminal deoxynucleotidyl transferase-mediated dU...
TMPJ-00605	GPVI Protein, Mouse, Recombinant (His) Glycoprotein 6,GP6,glycoprotein VI (platelet),GPVI,GPIV,MGC1...	Mouse	HEK293 Cells
	Glycoprotein VI (GPVI) is a 63 kDa platelet/megakaryocyte-specific type I transmembrane glycoprotein of the immunoglobulin superfamily that is an important collagen receptor and initiator of platelet activation, aggregation and thrombin generation. GPVI is also a secondary receptor required for platelet spreading on laminin. GPVI associates with the Fc receptor gamma -chain via charged aa in the TM domains of GPVI (arginine) and the FcR gamma (aspartic acid). Collagen binding by the GPVI Ig-like...

重组蛋白

Osteopontin Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00807

Species: Mouse

Expression System: HEK293 Cells

GAS6 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04830

Species: Mouse

Expression System: HEK293 Cells

MTHFS Protein, Human, Recombinant (His)

Cat.No: TMPJ-00989

Species: Human

Expression System: E. coli

Endoglin/CD105 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00359

Species: Human

Expression System: HEK293 Cells

FAM3B Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02640

Species: Human

Expression System: HEK293 Cells

GPVI Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00605

Species: Mouse

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
TMIH-0087	Amlodipine-d4 Maleate (Racemic)
	Amlodipine-d4 Maleate (Racemic) 是 Amlodipine Maleate (Racemic) 的氘代化合物。Amlodipine Maleate (Racemic) 的 CAS 号为 88150-47-4。Amlodipine maleate是一种具有口服活性的二氢吡啶类钙通道阻滞剂，通过阻滞电压依赖性L型钙通道，从而抑制钙离子内流。Amlodipine maleate可用于研究高血压和癌症。
TMIJ-0042	Metoprolol-d7 Hydrochloride
	Metoprolol-d7 Hydrochloride 是 Metoprolol Hydrochloride 的氘代化合物。Metoprolol Hydrochloride 的 CAS 号为 56392-18-8。Metoprolol 是一种选择性 β1 受体阻滞剂。Metoprolol 用于治疗高血压、因心脏血流不畅而引起的胸痛以及许多心率异常快的疾病。
T70186	Methazolamide-d6
	Methazolamide-d6 is intended for use as an internal standard for the quantification of methazolamide by GC- or LC-MS. Methazolamide is a carbonic anhydrase inhibitor. It reduces intraocular pressure and cerebrospinal fluid flow in a rat model of glaucoma. Methazolamide reduces electroshock-induced seizures in rats with an ED50 value of 19.2 mg/kg. It also inhibits production of reactive oxygen species (ROS) in a primary cortical neuron (PCN) cellular model of subarachnoid hemorrhage (SAH) and re...
TMIJ-0114	Vardenafil-d5
	Vardenafil-d5 是 Vardenafil 的氘代化合物。Vardenafil 的 CAS 号为 224785-90-4。Vardenafil 是选择性、高效的、具有口服活性的磷酸二酯酶5抑制剂，IC50=0.7 nM。它能够非竞争性地抑制环磷酸鸟苷水解，从而提高 cGMP 水平。它对 PDE1 (180 nM)，PDE6 (11 nM)，PDE2，PDE3，PDE4 (>1000 nM) 具有选择性。它可用于研究勃起功能障碍。

同位素标记化合物

Amlodipine-d4 Maleate (Racemic)

Cat.No: TMIH-0087

Metoprolol-d7 Hydrochloride

Cat.No: TMIJ-0042

Methazolamide-d6

Cat.No: T70186

Cat.No: TMIJ-0114

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